Matsumura Yasuhiro 松村保広

… Alternative Names

松村保広マツムラヤスヒロ

MATSUMURA Yasuhiro 松村保広

松村保宏マツムラヤスヒロ

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Researcher Number	90209619
Other IDs
Affiliation (Current)	2025: 株式会社凜研究所, 研究部門, 取締役 2025: 株式会社凜研究所, コーポレート部門, 取締役 2025: 国立研究開発法人国立がん研究センター, 研究所, 客員研究員
Affiliation (based on the past Project Information) *help	2024: 株式会社凜研究所, 研究部門, 取締役 2019 – 2022: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 分野長 2017: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 分野長 2014: 国立がん研究センター、臨床開発センター, 新薬開発分野, 分野長 2012: 独立行政法人国立がん研究センター, 臨床開発センター, 分野長 … More 2011: 独立行政法人国立がんセンター, がん治療開発部, 部長 2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, がん治療開発部, 部長 2008 – 2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, がん治療開発部, 部長 2007: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 国立がんセンター(研究所及び東病院臨床開発センターがん治療開発部, 部長 2006: 国立がんセンター(研究所及び東病院臨床開発センター), がん治療開発部), 部長 2005: 国立がんセンター(研究所及び東病院臨床開発センター), がん治療開発部, 部長 2004: 国立がんセンター研究所, 支所・がん治療開発部, 部長 1997 – 1998: 国立ガンセンター, 内科, 医員 1988 – 1989: 熊本大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Laboratory medicine / Biological Sciences Except Principal Investigator Basic Section 90120:Biomaterials-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Tumor therapeutics / Gastroenterology / Otorhinolaryngology / Gastroenterology / Cerebral neurosurgery / General surgery / Biological Sciences
Keywords	Principal Investigator イムノビーズ / 遺伝子診断 / 便潜血反応 / スクリーニング / 大腸がん / CPR-11 / CPT-11 / 遺伝子デリバリー / NK102 / NK105 … More / VEGF / CPT-1 / SN-38 / タキソール / ミセル / 薬理学 / 癌 / 医療・福祉 / 分子認識 / ナノ材料 … More Except Principal Investigator 抗体 / CD44 / 幹細胞 / 膵臓がん / 間質バリア / DDS / ADC / 融合タンパク / アルツハイマー病 / 急性期脳梗塞 / 薬物ターゲティング / 血栓溶解 / リンカー / ENGase / FcγR / 抗体薬物複合体 / 糖鎖 / ドラッグデリバリー / 間質 / 癌 / ドラッグイメージング / 分子イメージング / がん間質 / Liver function / Hepatitis / Fluminant hepatitis / Polyethylene glycol conjugate / Bilirubin oxidase / Kernicterus / Jaundice / Bilirubin / PEG結合酵素 / ポリエチレングリコール結合型酵素製剤 / 減黄療法 / 新生児核黄疸 / 肝不全 / ポリエチレングリコ-ル結合型酵素 / 肝硬変 / 黄疽 / 激症肝炎 / 核黄疸 / 肝機能 / ポリエチレングリコ-ル結合酵素 / ビリルビン分解酵素 / 肝炎 / 黄疸 / ビリルビン / CELL ADHESION MOLECULE / HEAD AND NECK CANCER / 細胞接着分子 / 頭頸部癌 / 癌性腹水 / 高分子型制癌剤 / 腫瘍の脈管特性 / ヒドロプロリルブラジキニン / ブラジキニン / 血管透過性因子 / 腫瘍血管の透過性 / 腫瘍血管 / 5-FU耐性 / バイオインフォマティクス / トランスポーター / 造血幹細胞 / がん幹細胞 / 抗がん剤耐性 / ５－ＦＵ / SLC6A6 / 大腸がん / ラジオアイソトープ / 動物実験モデル / GSC移植 / 幹細胞樹立 / GSC薬剤耐性 / GSC特異的抗体 / プロテオミクス / 抗体付加ミセル / 薬物内包ミセル / グリオーマ / 分子標的薬剤 / テモゾロマイド / ヌードマウス / GSC特異的細胞表面分子 / 薬剤内包ミセル / グリオーマ癌幹細胞(GSC) / 抗体インターナリゼーション / 悪性リンパ腫 / 抗体インタナリゼーション / in vivoイメージング / SN-38 / 悪性リンパ種 / 抗体デリバリー / siRNA / レセプター / トランスフェリン / 遺伝子デリバリー / がん Less

New frontiers of thrombolytic agents: Applications of a novel thrombolytic agent to acute and chronic cranial nerve diseases.
- Principal Investigator
  
  横山昌幸
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Jikei University School of Medicine
Investigation on relationship between glycan structure and antibody-drug conjugate function
- Principal Investigator
  
  Manabe Shino
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Hoshi University
  Institute of Physical and Chemical Research
Elucidation of the chemoresistance in pancreatic cancer and development of its tumor stroma targeting ADCs
- Principal Investigator
  
  Yasunaga Masahiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  National Cancer Center Japan
5-FU resistance mechanism between hematopoietic stem cells and colon cancer stem cells
- Principal Investigator
  
  YASUNAGA Masahiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  National Cancer Center Japan
Development of new anti-tumor therapy for malignant glioma using a drug incorporating polymeric micelle attached with a specific antibody for glioma cancer stem cell
- Principal Investigator
  
  KURATSU Jun-ichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kumamoto University
Analysis of the tumor biological factor regulating the antibody-delivery
- Principal Investigator
  
  YASUNAGA Masahiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Cancer Center Japan
Development of drug or gene delivery system for clinical application.Principal Investigator
- Principal Investigator
  
  松村保広
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
自然排出便中からの大腸がん細胞の分離法の開発とその大腸がん遺伝子診断への応用Principal Investigator
- Principal Investigator
  
  松村保広
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
臨床試験導入を目指した肝がん用in vivo高発現型人工遺伝子ベクターの開発
- Principal Investigator
  
  原島秀吉
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
PROGNOSTIC SIGNIFICANCE OF EXPRESSION OF CD44 VARIANTS IN HEAD AND NECK CANCER
- Principal Investigator
  
  FUJII Masato
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  KEIO UNIVERSITY
固型腫瘍における血管透過性亢進とキニン産生系の活性化
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
Preparation of Polymer Conjugated Bilirubin Oxidase and Development of Therapeatic Method for Jaundice.
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B).
- Research Field
  
  Gastroenterology
- Research Institution
  Kumamoto University

[Book] BIO Clinica2015
- Author(s)
  安永正浩、眞鍋史乃、松村保広
- Total Pages
  6
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-15H04316
[Book] ドラッグデリバリーシステムの新展開II2012
- Author(s)
  安永正浩、真鍋史乃、松村保広
- Total Pages
  278
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-22591447
[Book] 間質抗体を利用したがん標的治療ドラッグデリバリーシステムの新展開II2012
- Author(s)
  安永正浩、松村保広
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-22591447
[Journal Article] Contribution from Synthetic Organic Chemistry and Glycoscience to ADC Development: Homogeneous ADC Preparation and Development of Cancer Stromal Targeting Therapy2020
- Author(s)
  Manabe Shino、Yamaguchi Yoshiki、Matsumura Yasuhiro
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan
  
  Volume: 78 Issue: 5 Pages: 485-494
- DOI
  10.5059/yukigoseikyokaishi.78.485
- NAID
  130007841847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03362, KAKENHI-PROJECT-19H03357
[Journal Article] Imaging mass spectrometry for the precise design of antibody-drug conjugates.2016
- Author(s)
  1.Fujiwara Y, Furuta M, Manabe S, Koga Y, Yasunaga M, Matsumura Y
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 24954-24954
- DOI
  10.1038/srep24954
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04316
[Journal Article] Feasibility study of the Fab fragment of a monoclonal antibody against tissue factor as a diagnostic tool.2016
- Author(s)
  Tsumura R, Sato R, Furuya F, Koga Y, Yamamoto Y, Fujiwara Y, Yasunaga M, Matsumura Y.
- Journal Title
  
  Int J Oncol.
  
  Volume: 47 Issue: 6 Pages: 2107-2114
- DOI
  10.3892/ijo.2015.3210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04316
[Journal Article] Tumour imaging by the detection of fibrin clots in tumour stroma using an anti-fibrin Fab fragment.2016
- Author(s)
  Obonai T, Fuchigami H, Furuya F, Kozuka N, Yasunaga M, Matsumura Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 23613-23613
- DOI
  10.1038/srep23613
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04316
[Journal Article] Antitumor effect of antitissue factor antibody-MMAE conjugate in human pancreatic tumor xenografts.2015
- Author(s)
  Koga Y, Manabe S, Aihara Y, Sato R, Tsumura R, Iwafuji H, Furuya F, Fuchigami H, Fujiwara Y, Hisada Y, Yamamoto Y, Yasunaga M, Matsumura Y.
- Journal Title
  
  Int J Cancer.
  
  Volume: 137 Issue: 6 Pages: 1457-1466
- DOI
  10.1002/ijc.29492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04316
[Journal Article] Effect of combined treatment with the epirubicin-incorporating micelles (NC-6300) and 1,2-diaminocyclohexane platinum (II)-incorporating micelles (NC-4016) on a human gastric cancer model.2014
- Author(s)
  Yamamoto Y, Hyodo I, Takigahira M, Koga Y, Yasunaga M, Harada M, Hayashi T, Kato Y, Matsumua Y
- Journal Title
  
  International Journal of Cancer
  
  Volume: 135 Issue: 1 Pages: 214-223
- DOI
  10.1002/ijc.28651
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24650282, KAKENHI-PROJECT-25670376
[Journal Article] Role of SLC6A6 in promoting the survival and multidrug resistance of colorectal cancer2014
- Author(s)
  Yasunaga M, Matsumura Y
- Journal Title
  
  Sci Rep
  
  Volume: 4 Issue: 1 Pages: 4852-4852
- DOI
  10.1038/srep04852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650282, KAKENHI-PROJECT-25670376
[Journal Article] Tailored immunoconjugate therapy depending on a quantity of tumor stroma2013
- Author(s)
  Yasunaga M, Manabe S, Tarin D, Matsumura Y
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 231-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591447
[Journal Article] New concept of cytotoxic immunoconjugate therapy targeting cancer-induced fibrin clots.2011
- Author(s)
  Yasunaga M, Manabe S, Matsumura Y
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 1396-402
- NAID
  10029295613
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591447
[Journal Article] Cancer-stroma targeting therapy by cytotoxic immunoconjugate bound to the collagen 4 network in the tumor tissue.2011
- Author(s)
  Yasunaga M, Manabe S, Tarin D, Matsumura Y
- Journal Title
  
  Bioconjug Chem
  
  Volume: 22 Pages: 1776-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591447
[Journal Article] New concept of cytotoxic immunoconjugate therapy targeting cancer-induced fibrin clots2011
- Author(s)
  Yasunaga M, Manabe S, Matsumura Y
- Journal Title
  
  Cancer Science
  
  Volume: 102 Issue: 7 Pages: 1396-1402
- DOI
  10.1111/j.1349-7006.2011.01954.x
- NAID
  10029295613
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591447
[Journal Article] Cancer-stroma targeting therapy by cytotoxic immunoconjugate bound to the collagen 4 network in the tumor tissue2011
- Author(s)
  Yasunaga M, Manabe S, Tarin D, Matsumura Y
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 22 Issue: 9 Pages: 1776-1783
- DOI
  10.1021/bc200158j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591447
[Journal Article] The antitumor activity of NK012, a SN-38 incorporating micelle, in combination with bevacizumab against lung cancer xenografts.2010
- Author(s)
  H Kenmotsu, Y Matsumura, et al.
- Journal Title
  
  Cancer. (in press)
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Synergistic Antitumor Activity of the SN-38-Incorporating Polymeric Micelles NK012 with S-1 in a Mouse Model of Non-Small Cell Lung Cancer.2010
- Author(s)
  T Nagano, Y Matsumura, et al.
- Journal Title
  
  Int J Cancer. (in press.)
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Antitumor Effect of NK012, SN-38 Incorporating Polymeric Micelle on U87MG Orthotopic Glioblastoma in Mice Compared with Irinotecan in Combination with Bevacizumab.2010
- Author(s)
  J Kuroda, Y Matsumura, et al.
- Journal Title
  
  Clin Cancer Res. 16(2)
  
  Pages: 521-9
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Antitumor activity of NK012 combined with cisplatin against small-cell lung cancer and intestinal mucosal changes in tumor-bearing mouse after treatment.2009
- Author(s)
  T Nagano, Y Matsumura, et al.
- Journal Title
  
  Clin Cancer Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] NK012.2009
- Author(s)
  Y Matsumura.
- Journal Title
  
  Drugs of the Future. (Thomson Reuters) 34(4)
  
  Pages: 276-281
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Preclinical and clinical studies of anticancer agent-incorporating polymer micelles.2009
- Author(s)
  Y Matsumura, K Kataoka.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 572-579
- NAID
  10025143892
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Preclinical and clinical studies of anticancer agent-incorprating polymer micelles2009
- Author(s)
  Y Matsumura.
- Journal Title
  
  Cancer Sci 100
  
  Pages: 572-579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Detection of the DNA point mutation of colorectal cancer cells isolated from feces stored under different conditions.2009
- Author(s)
  Y Koga, Y Matsumura, et al.
- Journal Title
  
  Jpn J Clin Oncol. 39
  
  Pages: 62-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Potent antitumor effect of SN-38-incorporating polymeric micelle, NK012, against malignant glioma.2009
- Author(s)
  J Kuroda, Y Matsumura, et al.
- Journal Title
  
  Int J Cancer. 124
  
  Pages: 2505-2511
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Preclinical and clinical studies of anticancer agent-incorporating polymer micelles.2009
- Author(s)
  Y Matsumura, K Kataoka.
- Journal Title
  
  Cancer Sci 100
  
  Pages: 572-579
- NAID
  10025143892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Antitumor activity of NK012 combined with cisplatin against small-cell lung cancer and intestinal mucosal changes in tumor-bearing mouse after treatment.2009
- Author(s)
  T Nagano, Y Matsumura, et al.
- Journal Title
  
  Clin Cancer Res 15(13)
  
  Pages: 4348-4355
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Potent antitumor effect of SN-38-incorporating polymeric micelle, NK012, against malignant glioma.2009
- Author(s)
  J Kuroda, Y Matsumura, et al.
- Journal Title
  
  Int J Cancer 124
  
  Pages: 2505-2511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Antitumour activity of NK012, SN-38-Incorporating Polymeric Micelles, in Hypovascular Orthotopic Pancreatic Tumour.2009
- Author(s)
  Y Saito, Y Matsumura, et al.
- Journal Title
  
  Eur J Cancer 46
  
  Pages: 650-658
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] NK0122009
- Author(s)
  Y Matsumura.
- Journal Title
  
  Drugs of the Future. (Thomson Reuters) 34(4)
  
  Pages: 276-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Improved recovery of exfoliated colonocytes from feces using newly developed immuno-magnetic beads.2008
- Author(s)
  Y Koga, Y Matsumura, et al.
- Journal Title
  
  Gastroenterology Res Practice.
  
  Pages: 605273-605273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Polymeric micellar delivery systems in Oncology.2008
- Author(s)
  Y Matsumura.
- Journal Title
  
  Jpn J Clin Oncol. 38(12)
  
  Pages: 793-802
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Tumor specific ultrasound enhanced gene transfer in vivo with novel liposomal bubbles.2008
- Author(s)
  R Suzuki, Y Matsumura, et al.
- Journal Title
  
  Journal of controlled release. 125
  
  Pages: 137-144
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Novel SN-38-incorparated polymeric micelles,NKO12,stronglysupperss renal cancer progression2008
- Author(s)
  M, Sumitomo., Y, Matsumura., et. al.
- Journal Title
  
  Cancer Res 68
  
  Pages: 1631-1635
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Enhanced distribution of NKO12 and prolonged sustahled-release of SN-38 within tumors are the key strategic point for a hypovascular tumor2008
- Author(s)
  Y Saito, Y Matsumura, et. al.
- Journal Title
  
  Can Science
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Polymeric micellar delivery systems in Oncology.2008
- Author(s)
  Y Matsumura.
- Journal Title
  
  Jpn J Clin Oncol 38(12)
  
  Pages: 793-802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Detection of colorectal cancer cells from feces using quantitative real-time RT-PCR for colorectal cancer diagnosis.2008
- Author(s)
  Y Koga, Y Matsumura, et al.
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 1977-1983
- NAID
  10024011960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Genetic Variations and Haplotypes of ABCC2 encoding MRP2 in a Japanese population.2008
- Author(s)
  K Sai, Y Matsumura, et al.
- Journal Title
  
  Drug Metab. 23
  
  Pages: 139-147
- NAID
  10024188073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Enhanced distribution of NK012, a polymeric micelle-encapsulated SN-38, and sustained release of SN-38 within tumors can beat a hypovascular tumor.2008
- Author(s)
  Y Saito, Y Matsumura, et al.
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1258-1264
- NAID
  10024007743
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Synergistic antitumor activity of the novel SN-38-incorporating polymeric micelles, NK012, combined with 5-fluorouracil in a mouse model of colorectal cancer, as compared with that of irinotecan plus 5-fluorouracil.2008
- Author(s)
  Nakajima, T. E., Y Matsumura, et al.
- Journal Title
  
  Int J Cancer 122
  
  Pages: 2148-2153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Poly (amino acid) micelle nanocarriers in preclinical and clinical studies.2008
- Author(s)
  Y Matsumura.
- Journal Title
  
  Adv Drug Deliv Rev 60
  
  Pages: 899-914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Novel SN-38-incorporated polymeric micelle, NK012, strongly suppresses renal cancer progression.2008
- Author(s)
  M Sumitomo, Y Matsumura, et al.
- Journal Title
  
  Cancer Res 68
  
  Pages: 1631-1635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan.2008
- Author(s)
  Nakajima-Eguchi T, Y Matsumura, et al.
- Journal Title
  
  Cancer Res. 68(22)
  
  Pages: 9318-9322
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Tumor specific ultrasound enhanced gene transfer in vivo with novel liposomal bubbles.2008
- Author(s)
  R Suzuki, Y Matsumura, et al.
- Journal Title
  
  J Control Release 125
  
  Pages: 137-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan.2008
- Author(s)
  Nakajima, T. E., Y Matsumura, et al.
- Journal Title
  
  Cancer Res 68
  
  Pages: 9318-9322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Syneragistic antitumor activity of the novel SN-38 incorporating polymeric micelles, NK012, combined with 5-fluorouracil in a mouse model of colorectal cancer, as compared with that of irinotecan plus 5-fluorouracil.2008
- Author(s)
  T Nakajima, Y Matsumura, et al.
- Journal Title
  
  Int J Cancer. 122
  
  Pages: 2148-2153
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Syneragistic antitumor activity of the novel SN-38 incorporating polymeric micelles,NKO12,combined with 5-fluorouracil in a mouse model of colorectal cancer,as compared with that of irinotecan plus 5-fluorouracil2008
- Author(s)
  T, Nakajima, . Y, Matsumura., et. al.
- Journal Title
  
  Int J Cancer 122
  
  Pages: 2148-2153
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Novel SN-38-incorporated polymeric micelles, NK012, strongly suppress renal cancer progression.2008
- Author(s)
  M Sumitomo, Y Matsumura, et al.
- Journal Title
  
  Cancer Res. 68(6)
  
  Pages: 1631-1635
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Poly (amino acid) micelle nanocarriers in preclinical and clinical studies.2008
- Author(s)
  Y Matsumura.
- Journal Title
  
  In Advanced Drug Delivery Reviews (eds. VHL Lee, MK Forrest, and GS Kwon)(Elsevier B.V.V.) 60/8
  
  Pages: 899-914
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Low-intensity ultrasound and microbubbles enhance the antitumor effect of cisplatin.2008
- Author(s)
  Y Watanabe, Y Matsumura, et al.
- Journal Title
  
  Cancer Sci 99
  
  Pages: 2525-2531
- NAID
  10024014712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Polymeric micellar delivery systems in oncology.2008
- Author(s)
  Y Matsumura.
- Journal Title
  
  Jpn J Clin Oncol 60
  
  Pages: 793-802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Enhanced distribution of NK012 and prolonged sustained-release of SN-38 within tumors are the key strategic point for a hypovascular tumor.2008
- Author(s)
  Y Saito, Y Matsumura, et al.
- Journal Title
  
  Cancer Sci 99;6
  
  Pages: 1258-1264
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] A Phase I and Pharmacokinetic Study of NK105, a Paclitaxel-incorporating Micellar Nanoparticle Formulation.2007
- Author(s)
  T Hamaguchi, Y Matsumura, et al.
- Journal Title
  
  Brit J Cancer. 97
  
  Pages: 170-176
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Genetic variations and haplotype structures of the DPYDgene encoding dihydropyrimidine dehydrogenase in Japanese and their ethnic differences2007
- Author(s)
  K, Maekawa., Matsumura, Y., et. al.
- Journal Title
  
  J Hum Genet 52
  
  Pages: 804-819
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] A Phase I and Pharmacokinetic Study of NK105,a Paclitaxel-incorporating Micellar Nanoparticle Formulation2007
- Author(s)
  T, Hamaguchi., K, Kato., Y, Matsumura., et. al.
- Journal Title
  
  Brit J Cancer 97
  
  Pages: 170-176
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Preclinical and clinical studies of anticancer drug-incorporated polymeric micelles.2007
- Author(s)
  Y Matsumura.
- Journal Title
  
  J Drug Targeting 15(7-8)
  
  Pages: 507-517
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Expression profiling of fecal colonocytes for RNA-based screening of colorectal cancer2007
- Author(s)
  S, Yajima, . Y Matsumura., et. al.
- Journal Title
  
  Int J Oncol 31
  
  Pages: 1029-1037
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Prechnical and clinical studies of anticancer drug-incorporatedpolymeric micelles2007
- Author(s)
  Y, Matsumura.
- Journal Title
  
  J Drug Targeting 15
  
  Pages: 507-517
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitizing agent compared to free paclitaxel.2006
- Author(s)
  T Negishi, Y Matsumura, et al.
- Journal Title
  
  Brit J Cancer. 95
  
  Pages: 601-606
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitizing agent compared to free paclitaxel.2006
- Author(s)
  T Negishi, Y Matsumura
- Journal Title
  
  Brit J Cancer 95
  
  Pages: 601-606
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Novel SN-38-incorporated polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors.2006
- Author(s)
  F Koizumi, Y Matsumura, et al.
- Journal Title
  
  Cancer Res 66
  
  Pages: 10048-10056
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Novel SN-38-incorporated polymeric micelles, NK012, eradicate vascular endothelial growth factor- secreting bulky tumors.2006
- Author(s)
  F Koizumi, Y Matsumura
- Journal Title
  
  Cancer Res 66
  
  Pages: 10048-10056
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-Triggered Drug Release property : tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy.2005
- Author(s)
  Y Bae, Y Matsumura, et al.
- Journal Title
  
  Bioconjugate Chem. 16
  
  Pages: 122-130
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Cisplatin-Incorporating Polymeric Micelles (NC-6004) Can Reduce Nephrotoxicity and Neurotoxicity of Cisplatin in Rats.2005
- Author(s)
  H Uchino, Y Matsumura
- Journal Title
  
  Brit J Cancer 93
  
  Pages: 678-687
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel.2005
- Author(s)
  T Hamaguchi, Y Matsumura, et al.
- Journal Title
  
  Brit J Cancer. 92
  
  Pages: 1240-1246
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Cisplatin-Incorporating Polymeric Micelles (NC-6004) Can Reduce Nephrotoxicity and Neurotoxicity of Cisplatin in Rats.2005
- Author(s)
  H Uchino, Y Matsumura, et al.
- Journal Title
  
  Brit J Cancer. 93
  
  Pages: 678-687
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] A new methodology for isolating colonocytes from naturally evacuated feces and its clinical application to colorectal cancer diagnosis.2005
- Author(s)
  H Matushita, Y Matsumura et al.
- Journal Title
  
  Gastroenterology 129
  
  Pages: 1918-1927
- Data Source
  KAKENHI-PROJECT-17659172
[Journal Article] Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-Triggered Drug Release property: tumor permeability, controlled subcellular drug distribution, and enhanced in vivo antitumor efficacy.2005
- Author(s)
  Y Bae, Y Matsumura, et al.
- Journal Title
  
  Bioconjugate Chem. 16
  
  Pages: 122-130
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] NK105,a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumor activity and reduce the neurotoxicity of paclitaxel.2005
- Author(s)
  T hamaguchi, Y Matsumura
- Journal Title
  
  Brit J Cancer 92
  
  Pages: 1240-1246
- Data Source
  KAKENHI-PROJECT-17016087
[Journal Article] Phase I and Pharmacokinetic Study of MCC-465, a doxorubicin (DXR) encapsulated in PEG-immunoliposome, in patients with metastatic stomach cancer.2004
- Author(s)
  Y.Matsumura
- Journal Title
  
  Annals Oncol 15
  
  Pages: 517-525
- Data Source
  KAKENHI-PROJECT-16023201
[Journal Article] A phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin.2004
- Author(s)
  Y.Matsumura
- Journal Title
  
  British Journal of Cancer 91
  
  Pages: 1775-1781
- Data Source
  KAKENHI-PROJECT-16023201
[Patent] 大腸がんマーカーに対する抗体2010
- Inventor(s)
  松村保広、安永正浩、里深博幸、岡部洋子
- Industrial Property Rights Holder
  国立がん研究センター・株式会社バイオマトリックス研究所
- Industrial Property Number
  2010-195962
- Filing Date
  2010-09-01
- Data Source
  KAKENHI-PROJECT-22591447
[Patent] 抗フィブリン抗体・薬剤複合体による新規DDS製剤2010
- Inventor(s)
  松村保広、安永正浩、眞鍋史乃
- Industrial Property Rights Holder
  国立がん研究センター・理学研究所
- Industrial Property Number
  2010-139572
- Filing Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-22591447
[Patent] 癌間質の構成因子に対して特異的結合能を有する物質と抗腫瘍性化合物との複合体による新規の癌ターゲティング治療2008
- Inventor(s)
  松村保広, ら
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団独立行政法人理化学研究所
- Filing Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-17016087
[Patent] 癌間質の構成因子に対して特異的結合能を有する物質と抗腫瘍性化合物との複合体による新規の癌ターゲティング治療2008
- Inventor(s)
  松村保広, ら
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団, 独立行政法人理化学研究所
- Industrial Property Number
  2008-293930
- Filing Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-17016087
[Patent] 新規な抗フィブリン抗体
- Inventor(s)
  松村保広, ら
- Industrial Property Rights Holder
  (財)ヒューマンサイエンス振興財団独立行政法人理化学研究所
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] アルファ線放出核種アスタチン-211結合抗体の前臨床試験2022
- Author(s)
  高島大輝、眞鍋史乃、大貫和信、古賀宣勝、津村遼、安西高廣、Wang Yang, Yin Xiaojie, 佐藤望、重河優大、南部明弘、臼田祥子、羽場宏光、藤井博史、松村保広、安永正浩
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03357
[Presentation] 分子イメージングを駆使した難治性がんに対するantibody-drug conjugateの開発2016
- Author(s)
  安永正浩、眞鍋史乃、辻厚至、古田大、緒方是嗣、高島大輝、藤原悠起、古賀宣勝、佐賀恒夫、松村保広
- Organizer
  日本分子イメージング学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-15H04316
[Presentation] Development of antibody-drug conjugate against refractory cancer by utilizing molecular imaging2016
- Author(s)
  安永正浩、松村保広
- Organizer
  日本微小循環学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-15H04316
[Presentation] Development of ADC utilizing molecular imaging2016
- Author(s)
  Masahhiro Yasunaga, Shino Manabe, Atushi Tsuji, Masaru Furuta, Koretsugu Ogata, Yuki Fujiwara, Yoshikazu Koga, Yasuhiro Matsumura
- Organizer
  Antibody Engineering & Therapeutics
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-12-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04316
[Presentation] 難治性がんに対するantibody-drug conjugate（ADC)の開発2016
- Author(s)
  安永正浩、眞鍋史乃、辻厚至、古田大、緒方是嗣、高島大輝、藤原悠起、古賀宣勝、佐賀恒夫、松村保広
- Organizer
  日本DDS学会学術集会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-15H04316
[Presentation] Development of CAST therapy by utilizing molecular imaging2016
- Author(s)
  Masahhiro Yasunaga, Shino Manabe, Atushi Tsuji, Masaru Furuta, Koretsugu Ogata, Yuki Fujiwara, Yoshikazu Koga, Yasuhiro Matsumura.
- Organizer
  World Molecular Imaging Congress
- Place of Presentation
  New York, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04316
[Presentation] Visualisation of drug delivery and EPR effect by using microscopic mass spectrometry2015
- Author(s)
  安永正浩、古田大、緒方是嗣、藤原悠起、古賀宣勝、松村保広
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15H04316
[Presentation] Developmental strategy of CAST (Cancer stromal targeting) therapy2015
- Author(s)
  Yasunaga M, Manabe S, Matsumura Y.
- Organizer
  Antibody Engineering & Therapeutics
- Place of Presentation
  USA・San Diego
- Year and Date
  2015-12-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04316
[Presentation] Molecular imaging of drug delivery by using high resolution microscopic mass spectrometry2015
- Author(s)
  Yasunaga M, Furuta M, Ogata K, Fujiwara Y, Koga Y, Matsumura Y.
- Organizer
  World Molecular Imaging Congress
- Place of Presentation
  USA・Honolulu
- Year and Date
  2015-09-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04316
[Presentation] The prosurvival role of the taurine transporter SLC6A6 in multidrug resistance of colorectal cancer.2014
- Author(s)
  安永正浩、松村保広
- Organizer
  日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-25670376
[Presentation] Development of CAST (Cancer stromal targeting) diagnosis and therapy using anti-fibrin monoclonal antibody2013
- Author(s)
  安永正浩、杉野隆、辻厚至、佐賀恒夫、眞鍋史乃、松村保広
- Organizer
  第38回日本微小循環学会総会
- Place of Presentation
  東京慈恵会医科大学
- Year and Date
  2013-02-09
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] CAST(Cancer stromal targeting)療法による腫瘍微小循環の制御2012
- Author(s)
  安永正浩、眞鍋史乃、松村保広
- Organizer
  第37回日本微小循環学会
- Place of Presentation
  盛岡グランドホテル
- Year and Date
  2012-03-17
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] フィブリンを標的にしたPET・CTイメージングとがん診断への応用2012
- Author(s)
  安永正浩、辻厚至、杉野隆、佐賀恒夫、眞鍋史乃、松村保広
- Organizer
  第7回日本分子イメージング学会
- Place of Presentation
  アクトシティ浜松中ホール・コングレスセンター
- Year and Date
  2012-05-25
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] Development of fibrin-targeting CAST (Cancer stromal targeting) diagnosis and therapy2012
- Author(s)
  安永正浩、杉野隆、辻厚至、佐賀恒夫、眞鍋史乃、松村保広
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] Developmental strategy of CAST (Cancer stromal targeting) therapy using DDS (Drug delivery system) and Imaging technology2012
- Author(s)
  安永正浩、杉野隆、辻厚至、佐賀恒夫、眞鍋史乃、松村保広
- Organizer
  The Chemo-Bio Informatics Society Annual Meeting 2012
- Place of Presentation
  東京・タワーホール船堀
- Year and Date
  2012-10-15
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] 抗フィブリン抗体を用いたCancer Stroma targeting(CAST)診断法の開発2012
- Author(s)
  安永正浩、杉野隆、辻厚至、佐賀恒夫、真鍋史乃、松村保広
- Organizer
  第28回日本DDS学会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2012-07-05
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] 間質抗体を利用したがん標的治療法の開発2011
- Author(s)
  安永正浩、眞鍋史乃、松村保広
- Organizer
  第27回日本DDS学会
- Place of Presentation
  東京大学本郷キャンパス
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] in vivoイメージングを用いたがん間質ターゲットCAST療法の開発2011
- Author(s)
  安永正浩、久田洋平、眞鍋史乃、松村保広
- Organizer
  20回日本バイオイメージング学会
- Place of Presentation
  千歳科学技術大学
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] Development of Cancer Stromal Targeting (CAST) Therapy by Utlizing in vivo Imaging2011
- Author(s)
  安永正浩、眞鍋史乃、松村保広
- Organizer
  日本情報計算化学生物学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2011-11-09
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] in vivoイメージングによる腫瘍微小循環における抗体動態の解析2011
- Author(s)
  安永正浩、久田洋平、中村彰吾、松村保広
- Organizer
  第36回日本微小循環学会
- Place of Presentation
  名古屋市立大学病院
- Year and Date
  2011-02-12
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] In vivoイメージングを用いた抗体DDS製剤開発戦略2011
- Author(s)
  安永正浩、眞鍋史乃、久田洋平、中村彰吾、松村保広
- Organizer
  第6回日本分子イメージング学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] 腫瘍組織成分と細胞特性に応じた抗体抗がん剤複合体の治療戦略2011
- Author(s)
  安永正浩、眞鍋史乃、松村保広
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] 間質ターゲット2010
- Author(s)
  安永正浩、眞鍋史乃、松村保広
- Organizer
  日本生体医工学学会ナノメディシンフォーラム
- Place of Presentation
  東京慈恵会医科大学
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] エコメディシンをめざすDDS2010
- Author(s)
  松村保広
- Organizer
  第8回抗悪性腫瘍薬開発フオーラム
- Place of Presentation
  吉田富三記念講堂
- Year and Date
  2010-02-21
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] 特別講演がん治療におけるDDS2010
- Author(s)
  松村保広
- Organizer
  第24回冬季札幌がんセミナー
- Place of Presentation
  ロイトン札幌
- Year and Date
  2010-02-07
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] 間質バリア克服のための抗体DDS製剤の開発戦略2010
- Author(s)
  安永正浩、眞鍋史乃、松村保広
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  リーガロイヤルホテル大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22591447
[Presentation] がん治療におけるドラッグデリバリーシステム(DDS)2009
- Author(s)
  松村保広
- Organizer
  第7回茨城膵腫瘍研究会(IPOG)学術講演会
- Place of Presentation
  グランドホテル東雲
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] 臨床から学ぶDDSの新しい治療戦略2009
- Author(s)
  松村保広
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京ドームホテル
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Anticancer agents-incorporated micelle carrier systems under clinical evaluation2009
- Author(s)
  Y Matsumura.
- Organizer
  14th International Symposium on Recent Advances in Drug Delivery Systems
- Place of Presentation
  Salt Lake
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Anticancer agents-incorporated micelle carrier systems under clinical evaluation.2009
- Author(s)
  Y Matsumura
- Organizer
  The 14th International Symposium on Recent Advances in Drug Delivery Systems.
- Place of Presentation
  Salt Lake City, Utah, USA.
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Anticancer agents-incorporated micelle carrier systems underclinical evaluation.2009
- Author(s)
  Y Matsumura
- Organizer
  The 14^<th> International Symposium on Recent Advances in Drug Delivery Systems.
- Place of Presentation
  Salt Lake City, Utah, USA.
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] 教育講演「DDSの基礎から臨床」2009
- Author(s)
  松村保広
- Organizer
  第47回日本婦人科腫瘍学会学術集会
- Place of Presentation
  都市センター
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] A preclinical, clinical, and translational study on micelle carrier system in oncology.2008
- Author(s)
  Y. Matsumura
- Organizer
  6th International Nanomedicine and Drug Delivery Symposium.
- Place of Presentation
  Toronto, Canada.
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] NK012, a polymeric micelle formation containing SN-38, markedly enhanced the antitumor activity of SN-38 against orthotopic glioblastoma multiforme tumors in a mouse model.2008
- Author(s)
  J. Kuroda, M. Yasunaga, J. Kuratsu, Y. Matsumura.
- Organizer
  AACR Annual Meeting 2008.
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Clinical Development of Polymer Therapeutics in Japan.2008
- Author(s)
  Y. Matsumura.
- Organizer
  7th International Symposium on Polymer Therapeutics from Laboratory to Clinical Practice 27th.
- Place of Presentation
  Valencia, Spain
- Year and Date
  2008-05-27
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] SN-38内包高分子ミセル(NK012)の臨床第I相試験-中間報告2008
- Author(s)
  加藤健、松村保広, 他
- Organizer
  第24回日本DDS学会
- Place of Presentation
  六本木アカデミーヒルズ
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Novel SN-38-incorporated polymeric micelles, NK012, eradicate lung metastases and increase survival in the murine renal cancer model.2008
- Author(s)
  M Sumitomo, Y Matsumura, et al.
- Organizer
  American Urological Association Annual Meeting 2008
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] 胃癌同所移植腹膜播種マウスモデルにおけるSN-38内包ミセルNK012の抗腫瘍効果の検討2008
- Author(s)
  中島貴子、松村保広, 他
- Organizer
  第24回日本DDS学会
- Place of Presentation
  六本木アカデミーヒルズ
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] SN38 incorporating micelle, NK012, enhance the antitumor activity of SN38 in orthotopic glioblastoma compared to CPT-112008
- Author(s)
  J Kuroda, Y Matsumura, et al.
- Organizer
  第67回日本がん学会総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Preclinical, clinical, and translational studies of DDS.2008
- Author(s)
  Y Matsumura.
- Organizer
  第67回日本がん学会総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Antitumor activity of polymeric micelles incorporating SN-38 (NK012) in mouse models of orthotopically planted gastric carcinoma progressing peritoneal dissemination.2008
- Author(s)
  T E Nakajima, Y Matsumura, et al.
- Organizer
  99th AACR Annual meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Importance of enhanced distribution of NK012 and long-term, sustained-release of SN-38 for the treatment of hypovascular tumors.2008
- Author(s)
  Y Saito, Y Matsumura, et al.
- Organizer
  99th AACR Annual meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] The effect of NK012, SN-38-incorporating micelles against orthotopic pancreatic tumor xenografts.2008
- Author(s)
  Y Saito, Y Matsumura, et al.
- Organizer
  第67回日本がん学会総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Clinical Development of Polymer Therapeutics in Japan.2008
- Author(s)
  Y Matsumura
- Organizer
  International Symposium on Polymer Therapeutics From Laboratory to Clinical Practice 27^<th>.
- Place of Presentation
  Valencia, Spain
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] NK012, a polymeric micelle formulation containing SN-38, markedly enhanced the antitumor activity of SN-38 against orthotopic glioblastoma multiforme tumors in a mouse model.2008
- Author(s)
  J Kuroda, Y Matsumura, et al.
- Organizer
  99th AACR Annual meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Comparative study of new immuno-magnetic beads for isolation of exfoliated cells from feces as a non-invasive method for diagnosing colorectal cancer2008
- Author(s)
  Y. Koga, M. Yasunaga, H. Baba, Y. Matsumura.
- Organizer
  2008 AACR Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2008-04-13
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Local gene delivery combined with ultrasound and bubble-liposome against superficial bladder cancer.2008
- Author(s)
  Suguru Fujisawa, Yasuhiro Matsumura
- Organizer
  2008 AACR Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2008-04-13
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] AACR Annual Meeting2008. Importance of enhanced distribution of NK012 and long-term, sustained-release of SN-38 for the treatment of hypovascular tumors.2008
- Author(s)
  Yohei Saito, Masahiro Yasunaga, Junichiro Kuroda, Yoshikatsu Koga, Yasuhiro Matsumura.
- Organizer
  2008 AACR Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2008-04-13
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] 腫瘍血管の乏しい同所すい臓がんモデルに対するNK012の抗腫瘍効果2008
- Author(s)
  齋藤洋平、松村保広, 他
- Organizer
  第24回日本DDS学会
- Place of Presentation
  六本木アカデミーヒルズ
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Polymeric micellar delivery systems in preclinical and clinical and trials.2007
- Author(s)
  Y. Matsumura.
- Organizer
  38th International symposium of the princess Takamatsu cancer research fund.
- Place of Presentation
  Tokyo.
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] がん化学療法におけるミセルキャリアシステム2007
- Author(s)
  松村保広
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフイゴ横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Improved isolation of exfoliated cells from feces for noninvasive diagnosis of colorectal cancer: A comparative study of new immuno-magnetic beads.2007
- Author(s)
  Y. Koga, H. Matsushita, M. Yasunaga, H. Baba, Y. Matsumura
- Organizer
  2007 AACR Annual Meeting
- Place of Presentation
  Los Angeles
- Year and Date
  2007-04-15
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] NKO12,SN-38-incorprating micelles can eradicate pancreatic solid tumor with abundant stroma2007
- Author(s)
  齋藤洋平、安永正浩、松村保広
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] SN-38内包ミセルNKO12と5Fuとの併用療法はヒト大腸癌HT-29皮下腫瘍を完全に消滅させる2007
- Author(s)
  中島貴子、荒萌万里、小池浩代、三江直子、宮武浩子、金井智恵子、安永正浩、松村保広
- Organizer
  第23回日本DDS学会
- Place of Presentation
  ホテル日航熊本
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] SN38内包ミセル製剤NKO12の5Fuとの併用療法による大腸癌皮下腫瘍マウスにおける抗腫瘍効果の検討2007
- Author(s)
  中島貴子、松村保広、安永正浩、小泉史明、加藤健、濱口哲弥、山田康秀、白尾国昭、安田安博
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Arterial infusion of nucleic acids through rat carotid artery as an experimental local gene delivery system: Looking ahead to future clinical trials. Los Angels Convention Center. Los Angels Convention Center.2007
- Author(s)
  J. Kuroda, J. Kuratsu, Y. Matsumura.
- Organizer
  AACR Annual Meeting 2007.
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors2007
- Author(s)
  F. Koizumi, Y. Matsumura.
- Organizer
  98th AACR Annual meeting
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Micelle carrier system in cancer chemotherapy2007
- Author(s)
  松村保広
- Organizer
  第9回日米DDSシンポジウム
- Place of Presentation
  ハワイ州、マウイ
- Year and Date
  2007-12-18
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Micelle carrier system in cancer chemotherapy.2007
- Author(s)
  Y. Matsumura.
- Organizer
  9th US-Japan DDS symposium.
- Place of Presentation
  Maui.
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Synergistic antitumor activity of novel polymeric micelles incorporating SN-38(NK012)in combination with 5-fluorouracil (5-FU)in mouse model of colon cancer2007
- Author(s)
  中島貴子、松村保広、安永正浩、小泉史明、加藤健、濱口哲弥、山田康秀、白尾国昭、安田安博
- Organizer
  2007年アメリカがん学会年次総会
- Place of Presentation
  Los Angels Convention Center
- Year and Date
  2007-04-17
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Experimental Local Gene Delivery System: Looking Ahead to a Future Clinical Trial.2006
- Author(s)
  Y. Matsumura
- Organizer
  The 1st FIP-APSTJ joint Workshop on Gene Delivery Committee.
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Phase I study of NK105, a paclitaxel-incorporating micellar nanoparticle, in patients with advanced cancer.2006
- Author(s)
  K Kato, T Hamaguchi, H Yasui, T Okusaka, H Ueno, M Ikeda, K Shirao, Y Shimada, H Nakahama, K Muro, Y Matsumura.
- Organizer
  2006 ASCO.
- Place of Presentation
  Atlanta
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Novel SN-38-incorporating polymeric micelles, NK012, eradicate vascular endothelial growth factor-secreting bulky tumors.2006
- Author(s)
  F. Koizumi, Y. Matsumura
- Organizer
  The Joint Meeting of The 3rd ISC International Conference on Cancer Therapeutics The 11th International Symposium on Cancer Chemotherapy.
- Place of Presentation
  Tokyo.
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Novel SN-38-incorporated polymeric micelles, NK012 eradicate vascular endothelial growth factor-secreting bulky tumors.2006
- Author(s)
  F. Koizumi, Y. Matsumura
- Organizer
  97th AACR
- Place of Presentation
  Washington.
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] The cytotoxicity and intracellular distributions of MCC-465, pegylated liposomal doxorubicin tagged with newly developed monoclonal antibody GAH, in ovarian cancer cell lines.2005
- Author(s)
  K Shimada, T Kasamatsu, T Hasegawa, Y Kanai, H Niki, T Tagawa, Y Matsumura.
- Organizer
  96th AACR
- Place of Presentation
  Anaheim, California.
- Data Source
  KAKENHI-PROJECT-17016087
[Presentation] Preclinical and clinical study of NK105, a paclitaxel-incorporating micellar nanoparticle formation.2005
- Author(s)
  Y. Matsumura
- Organizer
  The 32th Controlled Release Society.
- Place of Presentation
  Miami.
- Data Source
  KAKENHI-PROJECT-17016087

1. MANABE Shino (60300901)

# of Collaborated Projects: 4 results

# of Collaborated Products: 26 results
2. YASUNAGA Masahiro (80450576)

# of Collaborated Projects: 4 results

# of Collaborated Products: 38 results
3. MAEDA Hiroshi (90004613)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KURATSU Jun-ichi (20145296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAKAMURA Hideo (30359963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MAKINO Keishi (90381011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HIDE Takuichiro (40421820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ARAKI Norie (80253722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KURODA Jun-ichiro (90536731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FUJII Masato (70129633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. IMANISHI Yorihisa (80255538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TOKUMARU Yutaka (60245579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TOMITA Toshiki (30276357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KANKE Minoru (20255540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KOJIMA Yuichiro (50215258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 原島秀吉 (00183567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 山本哲郎 (60112405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 加藤久雄 (80029959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 川口隆憲 (10045685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 鈴木磨郎 (90006081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 井上正康 (80040278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 小田達也 (60145307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 羽場宏光 (60360624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. 佐々木秀 (00459968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 横山昌幸 (20220577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 小松鉄平 (60723856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 石井源一郎 (00270869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 佐々木征治

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 山口芳樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsumura Yasuhiro 松村 保広

松村 保広 マツムラ ヤスヒロ

MATSUMURA Yasuhiro 松村 保広

松村 保宏 マツムラ ヤスヒロ

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Development of drug or gene delivery system for clinical application.Principal Investigator

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自然排出便中からの大腸がん細胞の分離法の開発とその大腸がん遺伝子診断への応用Principal Investigator

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[Book] BIO Clinica2015

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[Book] ドラッグデリバリーシステムの新展開II2012

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[Book] 間質抗体を利用したがん標的治療 ドラッグデリバリーシステムの新展開II2012

Author(s)

Matsumura Yasuhiro 松村保広

松村保広マツムラヤスヒロ

MATSUMURA Yasuhiro 松村保広

松村保宏マツムラヤスヒロ

[Book] 間質抗体を利用したがん標的治療ドラッグデリバリーシステムの新展開II2012