Ozaki Hiroaki 尾崎広明

… Alternative Names

OZAKI Hiroaki 尾崎広明

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Researcher Number	90211820
Other IDs
External Links
Affiliation (Current)	2025: 群馬大学, 大学院理工学府, 教授
Affiliation (based on the past Project Information) *help	2009 – 2010: Gunma University, 大学院・工学研究科, 教授 2008: Gunma University, 大学院・工学研究科, 准教授 2001 – 2004: 群馬大学, 工学部, 助教授 1997 – 2000: 群馬大学, 工学部, 助手
Review Section/Research Field	Principal Investigator Chemistry related to living body / Bioorganic chemistry Except Principal Investigator Bioorganic chemistry / Science and Engineering / Synthetic chemistry
Keywords	Principal Investigator ncRNA / 修飾核酸 / mRNA / アンセンス / siRNA / アンチセンス / 核酸 / RNA切断 / Tm / 機能性基 / 糖部2'位修飾 / DNA / ヌクレオシド … More Except Principal Investigator … More DNA / PCR / 機能性DNA / 生体機能利用 / DNAポリメラーゼ / 核酸 / 5-Substituted 2'-Deoxyuridines / Modified Nucleic Acids / 5-Substituted 2'-Deoxycytidines / Enzymatic reaction / DNA Catalyst / DNA Polymerase / 5位置換チミヂン / 化学合成 / オリゴヌクレオチド / 5位置換チミジン / 生体機能 / 酵素合成 / Aptamer / Molecular Recognition / Enzymatic Reaction / Modified Substrate / DNA polymerase / Modified DNA / Nucleic Acid / 試験管内選択 / DNA触媒 / DNAアプタマー / 糖鎖 / アプタマー / 分子認識 / 酵素反応 / 修飾基質 / 修飾DNA / Labeled DNA / Tris-Amine / RNA Cleaving Activity / 2-Substituted Deoxyuanosine Derivatives / 2'-Modiifed Nucleosides / 標識化 / アンチセンス核酸 / α-ヌクレオシド / 2'デオキシウリジン誘導体 / 2重鎖形成能 / 2'-位置換スクレオシド / トリスアシン / 標識化DNA / トリスアミン / RNA分解活性 / 2位置換グアノシン誘導体 / 2'-位置換ヌクレオシド / 2'-デオキシウリジン誘導体 / 修飾核酸 Less

Study on functional antisense nucleic acids for ncRNAPrincipal Investigator
- Principal Investigator
  
  OZAKI Hiroaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Gunma University
Enzymatic Synthesis of Modified DNAs by PCR, and Their Application
- Principal Investigator
  
  SAWAI Hiroaki
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Gunma University
Preparation of Novel Modified Oligonucleotides by Chemic-Enzymatic Method and Their Application for the production of New DNA Catalyst
- Principal Investigator
  
  SAWAI Hiroaki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Gunma University
2'位置換ヌクレオシドによる核酸二重鎖マイナーグルーブ内への機能性基の導入Principal Investigator
- Principal Investigator
  
  尾崎広明
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Gunma University
Preparation of Novel Modified Oligonucleotides and Their Application to Man-made Enzymes with Sequence-Specific RNA-Cleaving Activity
- Principal Investigator
  
  SAWAI Hiroaki
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Synthetic chemistry
- Research Institution
  Gunma University

All 2011 2010 2009 2004

All Journal Article Presentation

[Journal Article] Synthesis of modified siRNA bearing C-5 polyamine-substituted pyrimidine nucleoside in their 3'-overhang regions and its RNAi activity2011
- Author(s)
  Mohammad Mehedi Masud, Tomokazu Masuda, Yusuke Inoue, Masayasu Kuwahara, Hiroaki Sawai, Hiroaki Ozaki
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters Vol.21, No.2
  
  Pages: 715-717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20550147
[Journal Article] Synthesis and properties of oligodeoxyribonucleotides bearing a polyaminogroup at the 2' position via 2'-O-carbamoylmethyl and 2'-S-carbamoylmethyl groups2009
- Author(s)
  Hiroaki Ozaki
- Journal Title
  
  Nucleosides, Nucleotides & Nucleic Acids 28
  
  Pages: 943-952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20550147
[Journal Article] Selective Binding and Cleavage of DNA by Stereoisomers of N,N'-Bis(phenanthrolin-2-yl)-1,2-cycolhexanediamine Conjugate, and their Copper Complexes2004
- Author(s)
  K.Hyashi, R.Nakjima, I.Kiyosawa, H.Ozaki, H.Sawai
- Journal Title
  
  Chem.Lett. 33
  
  Pages: 684-685
- Data Source
  KAKENHI-PROJECT-13132202
[Journal Article] Bis(phenanthroline)-ethylenediamine conjugate displays excimer fluorescence upon binding with DNA2004
- Author(s)
  K.Hatashi, H.Akutsu, H.Ozaki, H.Sawai
- Journal Title
  
  Chem.Comm.
  
  Pages: 1386-1387
- Data Source
  KAKENHI-PROJECT-13132202
[Journal Article] Screening of modified DNA aptamers that recognize DNA secondary structure2004
- Author(s)
  M.Kuwahara, T.Kasamatsu, M.Hasgawa, A.Shoji, H.Ozaki, H.Sawai
- Journal Title
  
  Nucleic Acids Symp.Ser. 48
  
  Pages: 265-266
- Data Source
  KAKENHI-PROJECT-13132202
[Journal Article] Sialllyllactose-binding modified DNa aptamer bearing additional functionality by SELEX2004
- Author(s)
  M.M.Masud, M, M.Kuwahara, H.Ozaki, H.Sawai
- Journal Title
  
  Bioorg.Med.Chem. 12
  
  Pages: 1111-1120
- Data Source
  KAKENHI-PROJECT-13132202
[Journal Article] Detection of biomolecule by aotamer beacon2004
- Author(s)
  A.Nishihira, H.Ozaki, M.Wakabayashiu, M.Kuwahara, H.Sawai
- Journal Title
  
  Nucleic Acids Symp.Ser. 48
  
  Pages: 135-136
- Data Source
  KAKENHI-PROJECT-13132202
[Journal Article] 5位置換ピリミヂンヌクレオシドを含むオリゴヌクレオチドの合成とその性質2004
- Author(s)
  尾崎宏明, 桑原正靖, 澤井宏明
- Journal Title
  
  有機合成化学協会誌 62
  
  Pages: 1238-1248
- Data Source
  KAKENHI-PROJECT-13132202
[Journal Article] 5位置換ピリミヂンヌクレオシドを含むオリゴヌクレオチドの合成とその性質2004
- Author(s)
  尾崎宏明ほか
- Journal Title
  
  有機合成化学協会誌 62
  
  Pages: 1238-1248
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13132202
[Journal Article] 5位置換ピリミヂンヌクレオシドを含むオリゴヌクレオチドの合成とその性質2004
- Author(s)
  尾崎宏明ほか
- Journal Title
  
  有機合成化学協会誌 62
  
  Pages: 1238-1248
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13132202
[Presentation] Synthesis of modified siRNA and its activity for gene regulation2010
- Author(s)
  Mohammad Mehedi Masud, Tomokazu Masuda, Yusuke Inoue, Hiroaki Ozaki
- Organizer
  The 37th International symposium on Nucleic Acid Chemistry 2010
- Place of Presentation
  Hamagin Hall (Yokohama).
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-20550147
[Presentation] 3'オーバーハング領域に修飾ヌクレオシドを導入したsiRNAの合成とそのRNAi活性の検討2010
- Author(s)
  増田知和、Mohammad Mehedi Masud、井上裕介、桑原正靖、澤井宏明、尾崎広明
- Organizer
  日本化学会関東支部群馬地区地域懇談会
- Place of Presentation
  日本原子力研究開発機構(群馬県)
- Year and Date
  2010-11-22
- Data Source
  KAKENHI-PROJECT-20550147
[Presentation] 1,10-フェナンスロリン-ポリアミン複合体の開発と核酸の切断活性の検討2010
- Author(s)
  増田知和、Mohammad Mehedi Mohammad Mehedi、尾崎広明
- Organizer
  日本化学会第4回関東支部大会
- Place of Presentation
  筑波大学(筑波)
- Year and Date
  2010-08-30
- Data Source
  KAKENHI-PROJECT-20550147
[Presentation] 5位置換ピリミジンヌクレオシドを含む機能性核酸の合成とアンチセンス法への利用2009
- Author(s)
  増田知和、尾崎広明、Mohammad Mehedi Mohammad Mehedi、〓原正靖、澤井宏明
- Organizer
  日本化学会第3回関東支部大会
- Place of Presentation
  早稲田大学(東京)
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-20550147

1. SAWAI Hiroaki (70012648)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. INOUE Yusuke (90304302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. KUWAHARA Masayasu (40334130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 篠塚和夫 (20206105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 沢井宏明

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results

Ozaki Hiroaki 尾崎 広明

OZAKI Hiroaki 尾崎 広明

Research Projects

Research Products

Co-Researchers

Study on functional antisense nucleic acids for ncRNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Enzymatic Synthesis of Modified DNAs by PCR, and Their Application

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Preparation of Novel Modified Oligonucleotides by Chemic-Enzymatic Method and Their Application for the production of New DNA Catalyst

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

2'位置換ヌクレオシドによる核酸二重鎖マイナーグルーブ内への機能性基の導入Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Preparation of Novel Modified Oligonucleotides and Their Application to Man-made Enzymes with Sequence-Specific RNA-Cleaving Activity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Synthesis of modified siRNA bearing C-5 polyamine-substituted pyrimidine nucleoside in their 3'-overhang regions and its RNAi activity2011

Author(s)

Journal Title

Data Source

[Journal Article] Synthesis and properties of oligodeoxyribonucleotides bearing a polyaminogroup at the 2' position via 2'-O-carbamoylmethyl and 2'-S-carbamoylmethyl groups2009

Author(s)

Journal Title

Data Source

[Journal Article] Selective Binding and Cleavage of DNA by Stereoisomers of N,N'-Bis(phenanthrolin-2-yl)-1,2-cycolhexanediamine Conjugate, and their Copper Complexes2004

Author(s)

Journal Title

Data Source

[Journal Article] Bis(phenanthroline)-ethylenediamine conjugate displays excimer fluorescence upon binding with DNA2004

Author(s)

Journal Title

Data Source

[Journal Article] Screening of modified DNA aptamers that recognize DNA secondary structure2004

Author(s)

Journal Title

Data Source

[Journal Article] Sialllyllactose-binding modified DNa aptamer bearing additional functionality by SELEX2004

Author(s)

Journal Title

Data Source

[Journal Article] Detection of biomolecule by aotamer beacon2004

Author(s)

Journal Title

Data Source

[Journal Article] 5位置換ピリミヂンヌクレオシドを含むオリゴヌクレオチドの合成とその性質2004

Author(s)

Journal Title

Data Source

[Journal Article] 5位置換ピリミヂンヌクレオシドを含むオリゴヌクレオチドの合成とその性質2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] 5位置換ピリミヂンヌクレオシドを含むオリゴヌクレオチドの合成とその性質2004

Author(s)

Journal Title

Description

Data Source

[Presentation] Synthesis of modified siRNA and its activity for gene regulation2010

Author(s)

Organizer

Ozaki Hiroaki 尾崎広明

OZAKI Hiroaki 尾崎広明