Doi Takayuki 土井隆行

… Alternative Names

DOI Takayuki 土井隆行

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Researcher Number	90212076
Other IDs
External Links
Affiliation (Current)	2025: 東北大学, 薬学研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 東北大学, 薬学研究科, 教授 2015 – 2019: 東北大学, 薬学研究科, 教授 2017: 東北大学, 大学院薬学研究科, 教授 2012 – 2016: 東北大学, 薬学研究科(研究院), 教授 2009 – 2011: 東北大学, 大学院・薬学研究科, 教授 … More 2007: Tokyo Institute of Technology, 大学院・理工学研究科, 准教授 2006: Tokyo Institute of Technology, Department of Applied Chemistry, Graduate School of Science and Engineering, Associate Professor, 大学院理工学研究科, 助教授 2006: 東京工業大学, 理工学研究科, 助教授 2000 – 2005: 東京工業大学, 大学院・理工学研究科, 助教授 1999: 東京工業大学, 大学院・理工学研究科, 助手 1994 – 1999: T.I.T., Chem.Eng., Assistant Professor, 工学部, 助手 Less
Review Section/Research Field	Principal Investigator Science and Engineering / Synthetic chemistry / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Transformative Research Areas, Section (II) / Science and Engineering / Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Synthetic chemistry / Biomolecular chemistry / Living organism molecular science … More Except Principal Investigator … More Synthetic chemistry / Endocrinology / Science and Engineering / Bioorganic chemistry / Synthetic chemistry / Living organism molecular science Less
Keywords	Principal Investigator 環状ペプチド / フロー合成 / 固相合成 / HIVプロテアーゼ阻害剤 / 不斉水素化 / 均一系触媒 / コンビナトリアル合成 / 環状デプシペプチド / ルテニウム触媒 / デジタル有機合成 … More / 不斉合成 / 中分子 / 細胞毒性 / 全合成 / 有機合成 / 天然物 / 立体配座解析 / 非天然型アミノ酸 / 環化反応 / フラボン / マイクロリアクター / ヘテロ環 / テロメスタチン / 不斉配位子 / ロジウム触媒 / 環状デプチペプチド / 天然物合成 / ペプチド / 不斉アルドール反応 / 光反応 / 機械学習 / エノラート / 反応集積化 / polyazamacrocycles / cyclic peptides / cyclic amines / intramolecular Diels-Alder reaction / solid phase synthesis / theoretical calculation / combinatorial synthesis / 位置選択的合成 / 立体選択的合成 / 計算科学 / ペプチドテザー / N-アルキル化 / 開環反応 / アジリジン / パラジウム触媒 / カルポニル化 / ポリアザ環状化合物 / 環状アミン / 分子内Diels-Alder反応 / 理論計算 / Cyclic Peptides / Peptide Mimetics / Combinatorial Synthesis / Solid-phase Synthesis / Carbonylation / Mizoroki-Heck Reaction / Asymmetric Hydrogenation / Homogeneous Catalyzed Reaction / 10員環 / 分子力場計算 / 環状ジアミド / コンビナトリアルライブラリー / 非天然型ペプチド / ペプチドミメティック / カルボニル化 / 溝呂木-Heck反応 / 均一系触媒反応 / 三次元構造 / 創薬 / ミメティクス / 構造活性相関 / 三次元構造解析 / ケムバイオケム / インシリコ / ケモバイオケム / 部分還元 / 化合物ライブラリー / マクロラクタム化 / 生物活性天然物 / ペプチドミメティクス / 生物活性分子の合成 / フラボノイド / フェノール / アシル転位 / イノン / テロメアーゼ阻害剤 / デロメアーゼ阻害剤 / ライブラリー / スタチン / C_2対称分子 / C_2対称 … More Except Principal Investigator ヒドロホルミル化 / 化合物ライブラリー / Combinatorial Chemistry / ファイトアレキシンエリシター / オリゴ糖 / 固相合成 / コンビナトリアルケミストリー / Capnellene / 創薬 / π-アリルパラジウム / bite angle / ロジウム(I)触媒 / スクリーニング / 糖質応答転写因子 / ハイスループットスクリーニング / 糖尿病性腎症 / ChREBP / CRISPR/Cas9システム / マイクロフロー / 複合化 / 機能集積 / 反応集積化 / 生物機能制御 / 反応集積 / 中分子 / Cyclic Compounds / One-Pot Glycosylation / Solid-Phase Synthesis / Compound Libraries / Chemical Probes / Natural Products / 自動合成 / 並列合成装置 / パラジウム / クラボロン / シリルエーテル / フッ化糖 / ワンポットグリコシル化反応 / コア2 / 糖アミノ酸 / 天然有機化合物 / ライブラリー / アルドール反応 / パラジウム反応 / プロスタノイド / 固相合成法 / コンビトリアルケミストリー / 異常アミノ酸 / アミド結合 / 環状化合物 / ワンポットグリコシル化 / ケミカルプローブ / 天然物 / Sulfonate linker / Glycosylation / Orthogonality / oligosaccharides / Vitamin D_3 / Combinatorial library / solid-phase synthesis / アルキル化 / Wittig反応 / トリエン / グリコシリル化 / シリルリンカー / グリコシル化 / スルフォナートリンカー / ライブラリー構築 / スルホン酸エステルリンカー / グリコシル化反応 / オルソゴナル / ビタミンD_3 / コンビナトリアルライブラリー / Domino / Five-membered ring / Allene insertion / Carbin-carbon bond / Carbonylation / π-Allylpalladium / Palladium Catalyst / 一酸化炭素 / Domino型 / 5員環形成 / アレン挿入 / 炭素-炭素結合形成 / カルボニル化 / π-アリルパラジウム中間体 / パラジウム触媒 / 12-membered ring / intramolecular alkylation / moleculer mechanics / molecular design / biosynthesis / transannular reaction / antitumor / taxol / 12員環化合物 / 分子内アルキル化 / 分子力場計算 / 分子設計 / タキソ-ル生合成 / 渡環反応 / 抗ガン剤 / タキソ-ル / Conjugate addition / Organozincate / 1,3-Chirality transmission / Cyclization / pi-Allylpalladium / Bite-Angle / Hydroformylation / Rh(I)-Complex / 均一系触媒 / 触媒活性 / ジホスフィン / 二座配位子 / turnover frequency / 光学活性 / 位置選択性 / 官能基配向性 / CAChe計算 / ビナフトール / ホスファイト配位子 / 共役付加反応 / 有機亜鉛アート錯体 / 不斉移転 / 環化反応 / バイトアングル / ロジウム(I)錯体 / 分子プローブ / 生理活性 / 脳・神経 / 癌 / モノテルペン / 1,2-ジエン(アレン) / 環化-カルボニル化 / パラジウム(0)触媒 / ジアステレオ選択性 / 不斉合成 / スチレン / 5配位錯体 Less

中分子ペプチド創薬を支える高難度ペプチド天然物の全合成技術開発Principal Investigator
- Principal Investigator
  
  土井隆行
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
  Sections That Are Subject to Joint Review: Basic Section47010:Pharmaceutical chemistry and drug development sciences-related , Basic Section47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Tohoku University
Optimization of flow synthesis reaction conditions and database construction for autonomous organic synthesisPrincipal Investigator
- Principal Investigator
  
  土井隆行
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Tohoku University
Optimization of flow synthesis and application to diversed synthesisPrincipal Investigator
- Principal Investigator
  
  土井隆行
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Tohoku University
Total Synthesis and Drug Discovery Research of Middle Molecular Peptidic Natural ProductsPrincipal Investigator
- Principal Investigator
  
  土井隆行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tohoku University
Innovation of novel therapeutics against diabetic nephropathy targeting ChREBP
- Principal Investigator
  
  Sugawara Akira
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Endocrinology
- Research Institution
  Tohoku University
Middle molecular strategy: Creation of higher bio-functional molecules by integrated synthesis
- Principal Investigator
  
  Fukase Koichi
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
Middle-size cyclic peptides containing unnatural amino acids enable the control of higher cell functionPrincipal Investigator
- Principal Investigator
  
  DOI TAKAYUKI
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
ヒストン脱アセチル化酵素阻害剤の創製研究Principal Investigator
- Principal Investigator
  
  土井隆行
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
Development of drug discovery chemistry centered on cyclodepsipeptide natural productsPrincipal Investigator
- Principal Investigator
  
  Doi Takayuki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Tohoku University
フロー系を用いる骨格形成反応の開発と有機合成の効率化Principal Investigator
- Principal Investigator
  
  土井隆行
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
Synthesis of biologically acitive natural product cyclodepsipeptides and their analoguesPrincipal Investigator
- Principal Investigator
  
  DOI TAKAYUKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Tohoku University
フロー系を用いる骨格形成反応の開発研究Principal Investigator
- Principal Investigator
  
  土井隆行
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tohoku University
抗癌剤テロメスタチンを母骨格とするヒ合物ライブラリーの合成研究Principal Investigator
- Principal Investigator
  
  土井隆行
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
Chemical biology targeting the brain : Molecular design of anticancer agents that efficiently attack brain tumors
- Principal Investigator
  
  ISHIKAWA Toshihisa
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Living organism molecular science
- Research Institution
  Tokyo Institute of Technology
抗癌剤テロメスタチンを母骨格とする化合物ライブラリーの合成研究Principal Investigator
- Principal Investigator
  
  土井隆行
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
Design of Peptide-based Reaction Field and Molecular Recognition Site and Their SynthesisPrincipal Investigator
- Principal Investigator
  
  DOI Takayuki
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Tokyo Insitute of Technology
Solid-and Solution-Phase Synthesis of Natural Product-Based Libraries
- Principal Investigator
  
  TAKAHASHI Takashi
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Tokyo Institute of Technology
Development of solid-phase methodology for the synthesis of combinatorial library
- Principal Investigator
  
  TAKAHASHI Takashi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Tokyo Institute of Technology
Combinatorial Synthesis of Peptide Mimetics Containing Unnatural Amino Acid Utilizing Homogeneous Catalyzed ReactionsPrincipal Investigator
- Principal Investigator
  
  DOI Takayuki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Tokyo Institute of Technology
CYCLIZATION BY AN INTRAMOLECULAR ALLENE INSERTION INTO π-ALLYLIC PALLADIUMS AND BY CARBONYLATION
- Principal Investigator
  
  YAMAMOTO Kenji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Synthetic chemistry
- Research Institution
  SCIENCE UNIVERSITY OF TOKYO IN YAMAGUCHI
2重の不斉水素化を用いるHIVプロテアーゼ阻害剤コア部位の合成研究Principal Investigator
- Principal Investigator
  
  土井隆行
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Tokyo Institute of Technology
2度の不斉水素化を用いるHIVプロテアーゼ阻害剤コア部位の合成研究Principal Investigator
- Principal Investigator
  
  土井隆行
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Tokyo Institute of Technology
ロジウム(I)錯体の新規補助配位子の開発とヒドロホルミル化における選択性の研究
- Principal Investigator
  
  山本經二
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Institute of Technology
π-アリルパラジウム中間体を経るアルキン、ジエンの分子内挿入-カルボニル化の研究
- Principal Investigator
  
  山元經二
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Tokyo Institute of Technology
Design and Synthesis of Taxol Skeleton on the Basis of Molecular Mechanics Calculations
- Principal Investigator
  
  TAKAHASHI Takashi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Tokyo Institute of Technology
ロジウム(I)錯体の新規補助配位子の開発とヒドロホルミル化における選択性の研究
- Principal Investigator
  
  YAMAMOTO Keiji
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Institute of Technology
不斉水素化反応によるHIV逆転写酵素阻害剤の合成研究Principal Investigator
- Principal Investigator
  
  土井隆行
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Tokyo Institute of Technology
Study of the correlation between the structure of auxiliary ligands for transition metal complexes as catalysts and the selectivity in homogeneous catalytic reactions
- Principal Investigator
  
  YAMAMOTO Keiji
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Tokyo Institute of Technology

[Book] 遺伝子医学MOOK21号最新ペプチド合成技術とその創薬研究への応用2012
- Author(s)
  木曽良明, 土井隆行, 他
- Publisher
  株式会社メディカルドゥ
- Data Source
  KAKENHI-PROJECT-23310145
[Book] 「生物活性天然有機化合物環状デプシペプチド(-)-アプラトキシンA の全合成,固相合成,類縁体合成」,遺伝子医学MOOK21 最新ペプチド合成技術とその創薬研究への応用,木曽良明・向井秀仁編2012
- Author(s)
  土井隆行
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-23310145
[Book] 天然物合成で活躍した反応実験のコツとポイント2011
- Author(s)
  菅敏幸, 林雄二郎, 土井隆行, 他
- Publisher
  株式会社化学同人
- Data Source
  KAKENHI-PROJECT-23310145
[Journal Article] Synthesis and Biological Evaluation of Lysophosphatidic Acid Analogues Using Conformational Restriction and Bioisosteric Replacement Strategies2023
- Author(s)
  Abdelwahid Mazin A. S.、Ohsawa Kosuke、Uwamizu Akiharu、Kano Kuniyuki、Aoki Junken、Doi Takayuki
- Journal Title
  
  ACS Omega
  
  Volume: 8 Issue: 51 Pages: 49278-49288
- DOI
  10.1021/acsomega.3c07668
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-22H05336, KAKENHI-PROJECT-22H00438
[Journal Article] Synthetic studies for destruxins and biological evaluation for osteoclast-like multinucleated cells: a review2022
- Author(s)
  Yoshida Masahito、Nakagawa Hiroshi、Doi Takayuki
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 75 Issue: 8 Pages: 420-431
- DOI
  10.1038/s41429-022-00540-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24003
[Journal Article] The Concise Synthesis of a tert-Butoxycarbonyl Derivative of (3R,4S)-4-Amino-3-hydroxy-7-(N-nitrosohydroxyamino)-2,2-dimethylheptanoate, a Component of JBIR-1412022
- Author(s)
 Yasoshima Kotaro、Yoshida Masahito、Doi Takayuki
- Journal Title
 
 Bulletin of the Chemical Society of Japan
 
 Volume: 95 Issue: 5 Pages: 830-832
- DOI
 10.1246/bcsj.20220035
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-23K24003, KAKENHI-PROJECT-21J10337
[Journal Article] Photocatalyzed Oxidative Decarboxylation Forming Aminovinylcysteine Containing Peptides2022
- Author(s)
  Kumashiro Masaya、Ohsawa Kosuke、Doi Takayuki
- Journal Title
  
  Catalysts
  
  Volume: 12 Issue: 12 Pages: 1615-1615
- DOI
  10.3390/catal12121615
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15216, KAKENHI-PUBLICLY-22H05336, KAKENHI-PROJECT-23K24003
[Journal Article] Total Synthesis and Structural Determination of Cyclodepsipeptide Decatransin2022
- Author(s)
  Ohsawa Kosuke、Fukaya Sakiko、Doi Takayuki
- Journal Title
  
  Organic Letters
  
  Volume: 24 Issue: 30 Pages: 5552-5556
- DOI
  10.1021/acs.orglett.2c02085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24003
[Journal Article] Synthesis of a Biphenylalanine Analogue of Apratoxin A Displaying Substantially Enhanced Cytotoxicity2020
- Author(s)
  Doi Takayuki、Onda Yuichi、Fukushi Kazuki、Ohsawa Kosuke、Yoshida Masahito、Masuda Yuichi
- Journal Title
  
  HETEROCYCLES
  
  Volume: 101 Issue: 2 Pages: 679-691
- DOI
  10.3987/com-19-s(f)35
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Scalable Total Syntheses and Structure‐Activity Relationships of Haouamine A, B, and their Derivatives as Stable Formate Salts2020
- Author(s)
  Hirokazu Tsukamoto, Saki Nakamura, Akito Tomida, Takayuki Doi
- Journal Title
  
  Chemistry A European Journal
  
  Volume: 26 Issue: 55 Pages: 12528-12532
- DOI
  10.1002/chem.202001756
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Stereoselective Synthesis of Protected l-allo-Enduracididine and l-Enduracididine via Asymmetric Nitroaldol Reaction2020
- Author(s)
  Ohsawa Kosuke、Zhao Hongbin、Tokunaga Takuya、Thomas Carys、Ganesan A.、Masuda Yuichi、Doi Takayuki
- Journal Title
  
  Synthesis
  
  Volume: 52 Issue: 06 Pages: 942-948
- DOI
  10.1055/s-0039-1691522
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Structure–Activity Relationship Study on Col-003, a Protein–Protein Interaction Inhibitor between Collagen and Hsp472020
- Author(s)
  Yoshida Masahito、Saito Masazumi、Ito Shinya、Ogawa Koji、Goshima Naoki、Nagata Kazuhiro、Doi Takayuki
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 68 Issue: 3 Pages: 220-226
- DOI
  10.1248/cpb.c19-00634
- NAID
  130007804070
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2020-03-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Key Factors for High Diastereo- and Enantioselectivity of Umpolung Cyclizations of Aldehyde-Containing Allylpalladium Intermediates2019
- Author(s)
  Tsukamoto Hirokazu、Kawase Ayumu、Omura Hirotaka、Doi Takayuki
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 92 Issue: 10 Pages: 1743-1753
- DOI
  10.1246/bcsj.20190167
- NAID
  130007728663
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Palladium‐Catalyzed Umpolung Type‐II Cyclization of Allylic Carbonate‐Aldehydes Leading to 3‐Methylenecycloalkanol Derivatives2019
- Author(s)
  Tsukamoto Hirokazu、Kawase Ayumu、Doi Takayuki
- Journal Title
  
  Advanced Synthesis & Catalysis
  
  Volume: 361 Issue: 16 Pages: 3733-3738
- DOI
  10.1002/adsc.201900450
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Palladium(0)－Lithium Iodide Cocatalyzed Asymmetric Hydroalkylation of Conjugated Enynes with Pronucleophiles Leading to 1,3-Disubstituted Allenes2019
- Author(s)
  Hirokazu Tsukamoto, Tatsuya Konno, Kazuya Ito, and Takayuki Doi
- Journal Title
  
  Organic Letters
  
  Volume: 21 Issue: 17 Pages: 6811-6814
- DOI
  10.1021/acs.orglett.9b02439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06966, KAKENHI-PLANNED-15H05837
[Journal Article] Total Synthesis and Structural Revision of Cyclotetrapeptide Asperterrestide A2019
- Author(s)
  Ohsawa Kosuke、Sugai Masato、Zhang Linnan、Masuda Yuichi、Yoshida Masahito、Doi Takayuki
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 84 Issue: 11 Pages: 6765-6779
- DOI
  10.1021/acs.joc.9b00526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05841, KAKENHI-PLANNED-15H05837
[Journal Article] First Total Synthesis of Palmarumycin C6 based on Double Oxa-Michael Addition of 1,8-Dihydroxynaphthalene to 3-Bromo-1-indenone2019
- Author(s)
  Doi Takayuki、Tsukamoto Hirokazu、Nomura Yumi
- Journal Title
  
  HETEROCYCLES
  
  Volume: 99 Issue: 1 Pages: 549-565
- DOI
  10.3987/com-18-s(f)52
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Palladium(0)-catalyzed [4+2] Annulation of Salicylaldehydes and Propargyl Carbonates to Produce 3,4-Dihydro-2-methylene-2H-1-benzopyran-4-ols2019
- Author(s)
  Kawase Ayumu、Omura Hirotaka、Doi Takayuki、Tsukamoto Hirokazu
- Journal Title
  
  Chemistry Letters
  
  Volume: 48 Issue: 11 Pages: 1402-1405
- DOI
  10.1246/cl.190642
- NAID
  130007741835
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Cyclodepsipeptide Natural Products Apratoxins A and C and Their Analogs2018
- Author(s)
  T. Doi, Y. Masuda, M. Yoshida
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan
  
  Volume: 76 Issue: 11 Pages: 1170-1175
- DOI
  10.5059/yukigoseikyokaishi.76.1170
- NAID
  130007503326
- ISSN
  0037-9980, 1883-6526
- Year and Date
  2018-11-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Total Synthesis of Spiromamakone A and Structure Revision of Spiropreussione A2018
- Author(s)
  H. Tsukamoto, S.Hanada, Y. Nomura, T. Doi
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 86 Issue: 16 Pages: 9430-9441
- DOI
  10.1021/acs.joc.8b01075
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] onjugate Addition to Acylketene Acetals Derived from 1,8-Dihydroxynaphthalene and Its Application To Synthesize the Proposed Structure of Spiropreussione A2018
- Author(s)
  H. Tsukamoto, Y. Nomura, K. Fujiwara, S. Hanada, T. Doi
- Journal Title
  
  Organic Letters
  
  Volume: 20 Issue: 10 Pages: 3140-3143
- DOI
  10.1021/acs.orglett.8b01259
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] A total synthesis and biological evaluation of siladenoserinol A and its analogues2018
- Author(s)
  M. Yoshida, K. Saito, H. Kato, S. Tsukamoto, T. Doi
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 印刷中 Issue: 18 Pages: 5147-5150
- DOI
  10.1002/anie.201801659
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03994, KAKENHI-PROJECT-17H04646, KAKENHI-PLANNED-15H05837
[Journal Article] Conformation-Based Design and Synthesis of Apratoxin A Mimetics Modified at the α,β-Unsaturated Thiazoline Moiety2017
- Author(s)
  Onda Yuichi、Masuda Yuichi、Yoshida Masahito、Doi Takayuki
- Journal Title
  
  J. Med. Chem.
  
  Volume: 60 Issue: 15 Pages: 6751-6765
- DOI
  10.1021/acs.jmedchem.7b00833
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07707, KAKENHI-PROJECT-26282208, KAKENHI-PLANNED-15H05837
[Journal Article] Systematic Analysis of the Relationship among 3D Structure, Bioactivity, and Membrane Permeability of PF1171F, a Cyclic Hexapeptide with Paralyzing Effects on Silkworms2017
- Author(s)
  Masuda Yuichi、Tanaka Ren、Ganesan A.、Doi Takayuki
- Journal Title
  
  J. Org. Chem.
  
  Volume: 82 Issue: 21 Pages: 11447-11463
- DOI
  10.1021/acs.joc.7b01975
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07707, KAKENHI-PLANNED-15H05837
[Journal Article] Stereoselective Synthesis of beta-Amino Acid Derivatives by Asymmetric Mannich Reaction in Flow2017
- Author(s)
  M. Yoshida, K. Umeda, T. Doi
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 90 Issue: 10 Pages: 1157-1163
- DOI
  10.1246/bcsj.20170194
- NAID
  130006770674
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05837
[Journal Article] Selective inhibition of sterolO-acyltransferase 1 isozyme by beauveriolide III in intact cells2017
- Author(s)
  T. Ohshiro, K. Kobayashi, M. Ohba, D. Matsuda, L. L. Rudel, T. Takahashi, T. Doi, H. Tomoda
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 4163-4163
- DOI
  10.1038/s41598-017-04177-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05837, KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-16K18900
[Journal Article] Design, Synthesis, and Biological Evaluation of Beauveriolide Analogues Bearing Photoreactive Amino Acids2016
- Author(s)
  Masuda Y, Aoyama K, Yoshida M, Kobayashi K, Ohshiro T, Tomoda H, Doi T.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 64 Issue: 7 Pages: 754-765
- DOI
  10.1248/cpb.c16-00095
- NAID
  130005160040
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26253009, KAKENHI-PROJECT-26282208, KAKENHI-PROJECT-26850068, KAKENHI-PROJECT-16K07707, KAKENHI-PROJECT-16K18900
[Journal Article] Potent oxazoline analogue of apratoxin C: synthesis, biological evaluation, and conformational analysis.2016
- Author(s)
  Yoshida, M., Onda, Y., Masuda, Y., Doi, T.
- Journal Title
  
  Biopolymers (Peptide Science)
  
  Volume: 未定 Issue: 4 Pages: 404-414
- DOI
  10.1002/bip.22781
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26850068, KAKENHI-PROJECT-26282208
[Journal Article] Combinatorial Solid-Phase Synthesis and Biological Evaluation of Cyclodepsipeptide Destruxin B as a Negative Regulator for Osteoclast Morphology2016
- Author(s)
  H. Sato, M. Yoshida, H. Murase, H. Nakagawa, T. Doi
- Journal Title
  
  ACS Combinatorial Science
  
  Volume: 18 Issue: 9 Pages: 590-595
- DOI
  10.1021/acscombsci.6b00076
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-15H05837, KAKENHI-PROJECT-26282208
[Journal Article] Structure revision of similanamide to PF1171C by total synthesis.2015
- Author(s)
  Masuda, Y., Tanaka, R., Ganesan, A., Doi, T.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 78 Issue: 9 Pages: 2286-2291
- DOI
  10.1021/acs.jnatprod.5b00643
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26850068, KAKENHI-PROJECT-26282208
[Journal Article] Study for diastereoselective aldol reaction in flow: Synthesis of (E)-(S)-3-hydroxy-7-tritylthio-4-heptenoic acid, a key component of cyclodepsipeptide HDAC inhibitors2015
- Author(s)
  T. Doi, H. Otaka, K. Umeda, M. Yoshida
- Journal Title
  
  Tetrahedron
  
  Volume: 71 Issue: 37 Pages: 6463-6470
- DOI
  10.1016/j.tet.2015.05.051
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-26102709
[Journal Article] Solid-Phase Combinatorial Synthesis and Biological Evaluation of Destruxin E Analogues2015
- Author(s)
  M. Yoshida, Y. Ishida, K. Adachi, H. Murase, H. Nakagawa. T. Doi
- Journal Title
  
  Chemistry A European Journal
  
  Volume: 21 Issue: 50 Pages: 18417-18430
- DOI
  10.1002/chem.201502970
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26282208
[Journal Article] Total synthesis of cyclodepsipeptide spiruchostatin A on silyl-linked polymer-support2015
- Author(s)
  M. Yoshida, K. Sasahara, and T. Doi
- Journal Title
  
  Tetrahedron
  
  Volume: 71 Issue: 40 Pages: 7647-7653
- DOI
  10.1016/j.tet.2015.07.064
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26102709
[Journal Article] Synthesis of the Biologically Active Natural Product Cyclodepsipeptides Apratoxin A and Its Analogues2014
- Author(s)
  T. Doi
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 62 Issue: 8 Pages: 735-743
- DOI
  10.1248/cpb.c14-00268
- NAID
  130004677390
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-26102709
[Journal Article] Scalable Solution-Phase Synthesis of the Biologically Active Cyclodepsipeptide Destruxin E, a Potent Negative Regulator of Osteoclast Morphology2014
- Author(s)
  M. Yoshida, H. Sato, Y. Ishida, H. Nakagawa, T. Doi
- Journal Title
  
  J. Org. Chem
  
  Volume: 79(1) Issue: 1 Pages: 296-306
- DOI
  10.1021/jo402437z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310145, KAKENHI-PROJECT-24592822
[Journal Article] Total Synthesis and Characterization of Thielocin B1 as a Protein-Protein Interaction Inhibitor of PAC3 Homodimer2014
- Author(s)
  T. Doi, M. Yoshida, K. Ohsawa, K. Shin-ya, M. Takagi, Y. Uekusa, T. Yamaguchi, K. Kato, T. Hirokawa, T. Natsume
- Journal Title
  
  Chem. Sci
  
  Volume: 5 Issue: 5 Pages: 1860-1868
- DOI
  10.1039/c3sc53237b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310145, KAKENHI-PROJECT-24657113, KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008
[Journal Article] Total Synthesis and Conformational Analysis of Apratoxin C2014
- Author(s)
  Y. Masuda, J. Suzuki, Y. Onda, Y. Fujino, M. Yoshida, T. Doi
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 79 Issue: 17 Pages: 8000-8009
- DOI
  10.1021/jo501130b
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26282208, KAKENHI-PROJECT-26850068
[Journal Article] A concise total synthesis of biologically active frutinones via tributylphosphine-catalyzed tandem acyl transfer-cyclization2014
- Author(s)
  Masahito Yoshida, Koya Saito, Yuta Fujino, Takayuki Doi
- Journal Title
  
  Tetrahedron
  
  Volume: 70 Issue: 21 Pages: 3452-3458
- DOI
  10.1016/j.tet.2014.03.073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J05610, KAKENHI-PUBLICLY-24106703
[Journal Article] Synthesis of Hepta-oxazole Macrocyclic Analogues of Telomestatin and Evaluation of Their Telomerase Inhibitory Activities2013
- Author(s)
  K. Shibata, M. Yoshida, T. Takahashi, M. Takagi, K. Shin-ya, T. Doi
- Journal Title
  
  Bull. Chem. Soc. Jpn
  
  Volume: 86(12) Issue: 12 Pages: 1453-1465
- DOI
  10.1246/bcsj.20130198
- NAID
  130004153172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310145
[Journal Article] Design and synthesis of 2-phenyl-1,4-dioxa-spiro [4.5]deca-6,9-dien-8-ones as potential anticancer agents starting from cytotoxic spiromamakone A2013
- Author(s)
  S. Fuse, K. Inaba, M. Takagi, M. Tanaka, T. Hirokawa, K. Johmoto, H. Uekusa, K. Shin-ya, T. Takahashi, T. Doi
- Journal Title
  
  Eur. J. Med. Chem
  
  Volume: 66 Pages: 180-184
- DOI
  10.1016/j.ejmech.2013.05.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310145
[Journal Article] A Direct and Mild Formylation Method for Substituted Benzenes Utilizing Dichloromethyl Methyl Ether - Silver Trifluoromethanesulfonate2013
- Author(s)
  K. Ohsawa, M. Yoshida, T. Doi
- Journal Title
  
  J. Org. Chem
  
  Volume: 78(7) Issue: 7 Pages: 3438-3444
- DOI
  10.1021/jo400056k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310145
[Journal Article] Development of a Near Infrared Fluorescence Labeling Reagent : Synthesis of Indole-Functionalized Indocyanine Green Derivatives2012
- Author(s)
  T. Doi, K. Oikawa, J. Suzuki, M. Yoshida, N. Iki
- Journal Title
  
  Synlett
  
  Volume: 2 Issue: 02 Pages: 306-310
- DOI
  10.1055/s-0031-1290139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310145, KAKENHI-PROJECT-23655060
[Journal Article] Conformationally Restricted Analog and Biotin-Labeled Probe Based on Beauveriolide III2012
- Author(s)
  T. Doi. T. Muraoka, D. Ohshiro, D. Matsuda, M. Yoshida, T. Takahashi, S. Omura, H. Tomoda
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 22(1) Issue: 1 Pages: 696-699
- DOI
  10.1016/j.bmcl.2011.10.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310145
[Journal Article] Comprehensive Predictions of Target Proteins Based on Protein-Chemical Interaction Using Virtual Screening and Experimental Verifications.2012
- Author(s)
  Kobayashi H, et al Imoto M and Sakakibara Y.
- Journal Title
  
  BMC Chemical Biology
  
  Volume: 12 Issue: 1 Pages: 2-2
- DOI
  10.1186/1472-6769-12-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310140, KAKENHI-PROJECT-23310145
[Journal Article] 9-アザジュロリジンを触媒として用いる3-アロイルフラボン類の簡便合成2012
- Author(s)
  吉田将人,齋藤虹矢,藤野雄太,土井隆行
- Journal Title
  
  Chemical Communications
  
  Volume: 48巻 Issue: 96 Pages: 11796-11798
- DOI
  10.1039/c2cc37015h
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23710264, KAKENHI-PUBLICLY-24106703
[Journal Article] Tandem-type Pd(II)-catalyzed oxidative Heck reaction/intramolecular C-H amidation sequence : a novel route to 4-aryl-2-quinolinones2012
- Author(s)
  Kiyofumi Inamoto, Junpei Kawasaki, Kou Hiroya, Yoshinori Kondo, Takayuki Doi
- Journal Title
  
  Chemical Communications
  
  Volume: 48 Issue: 36 Pages: 4332-4334
- DOI
  10.1039/c2cc30600j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590001, KAKENHI-PUBLICLY-22106503, KAKENHI-PROJECT-23310145, KAKENHI-PROJECT-23790002, KAKENHI-PROJECT-24590029
[Journal Article] Use of Dimethyl Carbonate as a Solvent Greatly Enhances the Biaryl Coupling of Aryl Iodides and Organoboron Reagents without Adding Any Transition Metal Catalysts2012
- Author(s)
  K.Inamoto, C.Hasegawa, K.Hiroya, Y.Kondo, T.Osako, Y.Uozumi, T.Doi
- Journal Title
  
  Chemical Communications
  
  Volume: 48 Issue: 23 Pages: 2912-2914
- DOI
  10.1039/c2cc17401d
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22106503, KAKENHI-PROJECT-22750141, KAKENHI-PROJECT-23790002, KAKENHI-PUBLICLY-24106703
[Journal Article] Synthesis of γ-Benzopyranone by TfOH-Promoted Regioselective Cyclization of o-Alkynoylphenols2011
- Author(s)
  M.Yoshida, Y.Fujino, T.Doi
- Journal Title
  
  Organic Letters
  
  Volume: 13 Issue: 17 Pages: 4526-4529
- DOI
  10.1021/ol2016934
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22106503, KAKENHI-PROJECT-23710264
[Journal Article] Total Synthesis of Spiruchostatin B Aided by an Automated Synthesizer2011
- Author(s)
  S.Fuse, K.Okada, Y.Iijima, A.Munakata, K.Machida, T.Takahashi, M.Takagi, K.Shin-ya, T.Doi
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 9 Issue: 10 Pages: 3825-3833
- DOI
  10.1039/c0ob01169j
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22106503, KAKENHI-PROJECT-23310145
[Journal Article] Total Synthesis of Optically Active Lycopladine A by Utilizing Diastereoselective Protection of Carbonyl Group in a 1,3-Cyclohexanedione Derivative2011
- Author(s)
  Kou Hiroya, Yoshihiro Suwa, Yusuke Ichihashi, Kiyofumi Inamoto, Takayuki Doi
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 76 Issue: 11 Pages: 4522-4532
- DOI
  10.1021/jo200418y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590001, KAKENHI-PROJECT-23310145
[Journal Article] Shin-ya, Isolation of New Hexapeptides -JBIR-39 and JBIR-40- from a Marine Sponge-Derived Streptomyces sp. Sp080513SC-242011
- Author(s)
  I. Kozone, M. Izumikawa, K. Motohashi, A. Nagai, M. Yoshida, T. Doi, M. Takagi, K
- Journal Title
  
  J. Marine Sci. Res. Development
  
  Volume: 1(1) Pages: 1000101-1000101
- URL
  http://www.omicsonline.org/2155-9910/2155-9910-1-101.php
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310145
[Journal Article] Regioselective Synthesis of Flavone Derivatives via DMAP-catalyzed Cyclization of o-Alkynoylphenols2011
- Author(s)
  M.Yoshida, Y.Fujino, K.Saito, T.Doi
- Journal Title
  
  Tetrahedron
  
  Volume: 67 Issue: 51 Pages: 9993-9997
- DOI
  10.1016/j.tet.2011.09.063
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22106503, KAKENHI-PROJECT-23710264
[Journal Article] Use of Molecular Oxygen as a Reoxidant in the Synthesis of 2-Substituted Benzothiazoles via Palladium-Catalyzed C-H Functionalization/Intramolecular C-S Bond Formation2010
- Author(s)
  吉田将人, 土井隆行
- Journal Title
  
  Advanced Synthesis & Catalysis
  
  Volume: 352 Pages: 2643-2655
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22106503
[Journal Article] Continuous-How Synthesis of Vitamin D_32010
- Author(s)
  布施新一郎, 土井隆行
- Journal Title
  
  Chemical Communications
  
  Volume: 46 Pages: 8722-8724
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22106503
[Journal Article] Synthesis, Structure Determination and Biological Evaluation of Destruxin E2010
- Author(s)
  吉田将人, 土井隆行
- Journal Title
  
  Organic Letters
  
  Volume: 12 Pages: 3792-3795
- NAID
  110009757785
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22106503
[Journal Article] Sequential Palladiurn-catalyzed Coupling Reactions on Solid-phase2008
- Author(s)
  Takayuki Doi
- Journal Title
  
  J. Comb. Chem. 10(1)
  
  Pages: 135-141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18032028
[Journal Article] Donor-bound Glycosylation for Various Glycosyl Acceptors : Bidirectional Solid-phase Semisynthesis of Vancomycin and Its Derivatives.2007
- Author(s)
  Takayuki Doi, Atsushi Kinbara, Hitoshi Inoue, Takashi Takahashi
- Journal Title
  
  Chem.Asian J. 1
  
  Pages: 188-198
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14103013
[Journal Article] Synthesis of Dimethyl Gloiosiphone A by Way of Palladium-catalyzed Domino Cycylization2007
- Author(s)
  Takayuki Doi
- Journal Title
  
  J. Org. Chem. 72(1)
  
  Pages: 3667-3671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18032028
[Journal Article] Donor-bound Glycosylation for Various Glycosyl Acceptors : Bidirectional Solid-phase Semisynthesis of Vancomycin and Its Derivatives.2007
- Author(s)
  Takayuki Doi
- Journal Title
  
  Chem. Asian J. 2(1)
  
  Pages: 188-198
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14103013
[Journal Article] A Total Synthesis of Apratoxin A,2006
- Author(s)
  Takayuki Doi
- Journal Title
  
  Org. Lett. 8(3)
  
  Pages: 531-534
- NAID
  10021906534
- Data Source
  KAKENHI-PROJECT-16350051
[Journal Article] A Total Synthesis of Spiruchostatin A2006
- Author(s)
  Takayuki Doi
- Journal Title
  
  Tetrahedron Lett. 47(7)
  
  Pages: 1177-1180
- NAID
  10020528667
- Data Source
  KAKENHI-PROJECT-18032028
[Journal Article] A Formal Total Synthesis of Taxol Aided by an Automated Synthesizer,2006
- Author(s)
  Takayuki Doi
- Journal Title
  
  Chemistry- An Asian Journal 1(3)
  
  Pages: 370-383
- Data Source
  KAKENHI-PROJECT-16350051
[Journal Article] Solid-phase Combinatorial Synthesis of Aeruginosin Derivatives and Their Biological Evaluation.2006
- Author(s)
  Takayuki Doi
- Journal Title
  
  J. Comb. Chem. 8
  
  Pages: 571-582
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14103013
[Journal Article] A total synthesis of spiruchostatin A.2006
- Author(s)
  Takayuki Doi
- Journal Title
  
  Tetrahedron Lett. 47
  
  Pages: 1177-1180
- NAID
  10020528667
- Data Source
  KAKENHI-PROJECT-16350051
[Journal Article] A Total Synthesis of Spiruchostatin A2006
- Author(s)
  Takayuki Doi
- Journal Title
  
  Tetrahedron Lett. 47(7)
  
  Pages: 1177-1180
- NAID
  10020528667
- Data Source
  KAKENHI-PROJECT-17035026
[Journal Article] A total synthesis of apratoxin A2006
- Author(s)
  Takayuki Doi
- Journal Title
  
  Organic Letters 8(3)
  
  Pages: 531-534
- NAID
  10021906534
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16350051
[Journal Article] Solid-Phase Combinatorial Synthesis of Aeruginosin Derivatives and Their Biological Evaluation,2006
- Author(s)
  Takayuki Doi
- Journal Title
  
  J. Comb. Chem. 8(4)
  
  Pages: 571-582
- Data Source
  KAKENHI-PROJECT-16350051
[Journal Article] A total synthesis of apratoxin A2006
- Author(s)
  Doi, Takayuki
- Journal Title
  
  Organic Letters 8・3
  
  Pages: 531-534
- NAID
  10021906534
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16350051
[Journal Article] Total Synthesis of (R)-Telomestatin2006
- Author(s)
  Takayuki Doi
- Journal Title
  
  Organic Letters 8(18)
  
  Pages: 4165-4167
- Data Source
  KAKENHI-PROJECT-18032028
[Journal Article] A Total Synthesis of Apratoxin A.2006
- Author(s)
  Takayuki Doi
- Journal Title
  
  Org.Lett. 8(3)
  
  Pages: 531-534
- NAID
  10021906534
- Data Source
  KAKENHI-PROJECT-14103013
[Journal Article] Solid-phase Combinatorial Synthesis of Aeruginosin Derivatives and Their Biological Evaluation.2006
- Author(s)
  Takayuki Doi, Yoichiro Hoshina, Hiroyuki Mogi, Yoshifumi Yamada, Takashi Takahashi
- Journal Title
  
  J.Comb.Chem. 8
  
  Pages: 571-582
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14103013
[Journal Article] Regio- and stereocontrolled Diels-Alder reaction tethered by Asp-Thr dipeptide2005
- Author(s)
  Doi, Takayuki
- Journal Title
  
  Chemical Communications 2005・39
  
  Pages: 4908-4910
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16350051
[Journal Article] Regio- and Stereo-controlled Diels-Alder Reaction Tethered by Asp-Thr Dipeptide.2005
- Author(s)
  Takayuki Doi
- Journal Title
  
  Chem.Commun. (39)
  
  Pages: 4908-4910
- Data Source
  KAKENHI-PROJECT-16350051
[Journal Article] Regio-and stereocontrolled Diels-Alder reaction tethered by Asp-Thr dipeptide2005
- Author(s)
  Takayuki Doi
- Journal Title
  
  Chemical Communications (39)
  
  Pages: 4908-4910
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16350051
[Journal Article] コンビナトリアルケミストリーの手法と液晶合成への応用2004
- Author(s)
  土井隆行
- Journal Title
  
  液晶 8・4
  
  Pages: 235-242
- NAID
  10013718232
- Data Source
  KAKENHI-PROJECT-16350051
[Journal Article] Selective Capture of 1-α,25-(OH)_2-Previtamin D_3 Utilizing Polymer-supported Trialkylsilvl Triflate in the Synthesis of 1-α-25-(OH)_2-Vitamin D_32004
- Author(s)
  Takayuki DOI
- Journal Title
  
  Tetrahedron Lett. 45・29
  
  Pages: 5727-5729
- Data Source
  KAKENHI-PROJECT-16350051
[Journal Article] An Efficient Synthesis of Polymer-supported Silyl Linkers Using a di-Grignard Reagent2004
- Author(s)
  Takayuki DOI
- Journal Title
  
  Tetrahedron Lett. 45・29
  
  Pages: 5723-5726
- Data Source
  KAKENHI-PROJECT-16350051
[Journal Article] A Combinatorial Synthesis of a Macrosphelide Library Utilizing a Palladium-Catalyzed Carbonylation on a Polymer Support.2003
- Author(s)
  Takashi Takahashi, Shin-ichi Kusaka, Takayuki Doi, Toshiaki Sunazuka, Satoshi Omura
- Journal Title
  
  Angew.Chem.Int. 42
  
  Pages: 5230-5234
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14103013
[Journal Article] Solid Phase Library Synthesis of Cyclic Depsipeptides : Aurilide and Aurilide Analogues.2003
- Author(s)
  Takashi Takahashi, Hiroyuki Nagamiya, Takayuki Doi, Peter G.Griffiths, Andrew M.Bray
- Journal Title
  
  J.Comb.Chem. 5
  
  Pages: 414-428
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14103013
[Patent] 環状デプシペプチド化合物2016
- Inventor(s)
  土井隆行，吉田将人，増田裕一，恩田勇一
- Industrial Property Rights Holder
  土井隆行，吉田将人，増田裕一，恩田勇一
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-027262
- Filing Date
  2016-02-16
- Data Source
  KAKENHI-PROJECT-26282208
[Patent] 環状デプシペプチドの新規使用方法2012
- Inventor(s)
  中尾洋一、前島寛、土井隆行、山下潤、魚崎英毅、福島弘之
- Industrial Property Rights Holder
  中尾洋一、前島寛、土井隆行、山下潤、魚崎英毅、福島弘之
- Industrial Property Rights Type
  特許
- Filing Date
  2012-09-03
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] ベイズ最適化を利用したマイクロフロー合成による不斉アルドール反応の開発2024
- Author(s)
  菅原勇真、大澤宏祐、土井隆行
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PUBLICLY-22H05336
[Presentation] 分枝ペプチド抗生物質Stalobacin Iに含まれるシクロプロパン含有α-ヒドロキシカルボン酸の立体選択的合成2023
- Author(s)
  大澤宏祐、稲垣達也、土井隆行
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K24003
[Presentation] Development of S-[2-Aminovinyl]-3-methylcystein Construction Using Photoreaction2023
- Author(s)
  Masaya Kumashiro, Kosuke Ohsawa, Takayuki Doi
- Organizer
  The 2nd International Symposium on Digitalization-driven Transformative Organic Synthesis
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H05336
[Presentation] Total Synthesis of Decatransin, Cyclodepsipeptide Natural Product2023
- Author(s)
  Takayuki Doi
- Organizer
  The 17th Chinese International Peptide Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H05336
[Presentation] Development of S-[2-aminovinyl]-3-methylcysteine construction using photoreaction2023
- Author(s)
  Masaya Kumashiro, Kosuke Ohsawa, Takayuki Doi
- Organizer
  The 60th Japanese Peptide Symposium
- Data Source
  KAKENHI-PUBLICLY-22H05336
[Presentation] Investigation of asymmetric aldol reaction in flow using Bayesian optimization2023
- Author(s)
  Yuma Sugawara, Kosuke Ohsawa, Takayuki Doi
- Organizer
  The 3rd International Conference on Automated Flow and Microreactor Synthesis
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H05336
[Presentation] 光反応を用いたAviMeCys構築法の開発2023
- Author(s)
  神代格也、大澤宏祐、土井隆行
- Organizer
  第52回複素環化学討論会
- Data Source
  KAKENHI-PUBLICLY-22H05336
[Presentation] オキサゾリン・N-ニトロソヒドロキシルアミン・3-アシルテトラミン酸を含有するJBIR-141の全合成研究2022
- Author(s)
  八十島浩太郎、吉田将人、河原哲平、橋本拓哉、新家一男、土井隆行
- Organizer
  第64回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-23K24003
[Presentation] 三次元構造に基づいたα-ヘリックス Apratoxin A ミメティクスの創製研究2022
- Author(s)
  大澤宏祐, 菅原勇真, 福士和希, 道上雅孝, 藤井郁雄, 広川貴次, 土井隆行
- Organizer
  第61回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-23K24003
[Presentation] シデロフォア構造をもつ環状ペプチド ASP2397 の全合成研究2022
- Author(s)
  大澤宏祐, 杜雨桐, 八十島浩太郎, 土井隆行
- Organizer
  第39回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-23K24003
[Presentation] Total synthesis and structural determination of cyclodepsipeptide decatransin2022
- Author(s)
  Kosuke Ohsawa, Sakiko Fukaya, Takayuki Doi
- Organizer
  The 59th Japanese Peptide Symposium
- Data Source
  KAKENHI-PROJECT-23K24003
[Presentation] オキサゾリン・N-ニトロソヒドロキシルアミン・3-アシルテトラミン酸を含有するJBIR-141の全合成研究2022
- Author(s)
  八十島浩太郎、吉田将人、河原哲平、橋本拓哉、新家一男、土井隆行
- Organizer
  第64回天然有機化合物討論会
- Data Source
  KAKENHI-PUBLICLY-22H05336
[Presentation] フォトレドックス反応を用いた新規AviMeCys構築法の開発2022
- Author(s)
  神代格也、大澤宏祐、土井隆行
- Organizer
  第121回有機合成シンポジウム
- Data Source
  KAKENHI-PUBLICLY-22H05336
[Presentation] フォトレドックス反応を用いた新規AviMeCys構築法の開発2022
- Author(s)
  神代格也、大澤宏祐、土井隆行
- Organizer
  第121回有機合成シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24003
[Presentation] Synthesis and Biological Evaluation of 3D Structure-Mimicked Apratoxin A Analogues2019
- Author(s)
  Takayuki Doi, Kazuki Fukushi, Yuichi Onda, Masahito Yoshida
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 光学活性なシクロヘキセノンのβ脱離を利用したhaouamine類の全合成研究2019
- Author(s)
  塚本裕一、富田昂仁、中村早希、土井隆行
- Organizer
  第116回有機合成シンポジウム
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 構造活性相関研究を指向した生物活性新奇鎖状ペプチドJBIR-126の全合成2019
- Author(s)
  大山皓介、吉田将人、新家一男、土井隆行
- Organizer
  第115回有機合成シンポジウム
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 環状テトラペプチドAsperterrestide A の全合成および構造訂正2019
- Author(s)
  大澤宏祐、菅井柾人、張林楠、増田裕一、吉田将人、土井隆行
- Organizer
  第61回天然有機化合物討論会
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 中分子環状ペプチドの合成、生物活性、三次元構造2019
- Author(s)
  土井隆行
- Organizer
  日本化学会第99春季年会
- Invited
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 三次元構造を模倣したapratoxin A誘導体の合成と生物活性評価2019
- Author(s)
  土井隆行，福士和希，恩田勇一，吉田将人
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] Synthetic study for novel Foxo3a inhibitor JBIR-1412019
- Author(s)
  Kotaro Yasoshima, Masahito Yoshida, Teppei Kawahara, Kazuo Shin-ya, and Takayuki Doi
- Organizer
  The 56th Japanese Peptide Symposium
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 生物活性をもつ中分子環状ペプチドの合成と三次元構造解析2019
- Author(s)
  土井隆行
- Organizer
  第9回CSJ化学フェスタ2019
- Invited
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 0価パラジウム触媒を用いた共役エンインのヒドロアルキル化反応による光学活性アレン合成法の開発2019
- Author(s)
  伊藤和也，金野達也，土井隆行，塚本裕一
- Organizer
  第45回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 光学活性アジリジンに対する連続アルキル化反応を鍵としたカルノサジン類の効率的合成法の開発2018
- Author(s)
  大澤宏祐，窪田準也，土井隆行
- Organizer
  第114回有機合成シンポジウム
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 新規抗菌活性を有するTeixobactin の合成研究2018
- Author(s)
  大澤宏祐, 徳永拓野, Thomas Carys, A. Ganesan, 増田裕一, 土井隆行
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] Synthesis, 3D Structure Analysis, and Biological Evaluation of Apratoxin A and Its Analogues2018
- Author(s)
  Takayuki Doi
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 抗腫瘍活性を有するAsperterrestide A の合成研究2018
- Author(s)
  大澤宏祐, 菅井柾人, 張林楠, 増田裕一, 吉田将人, 土井隆行
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] デストラキシンB ラクタム誘導体の全合成と生物活性評価2018
- Author(s)
  吉田将人, 今野源, 丹羽悠菜, 中川大, 土井隆行
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 創薬展開を指向した中分子環状ペプチドdestruxin 類の合成を基盤とする機能評価と高活性分子プローブの創製2017
- Author(s)
  吉田将人，佐藤寛，安達謙太, 今野源, 石田恵崇，村瀬隼人，丹羽悠菜，中川大，土井隆行
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] Teixobactinの合成研究2017
- Author(s)
  大澤宏祐，徳永拓野，増田裕一，土井隆行
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内キャンパス，仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] Synthetic study for teixobactin2017
- Author(s)
  K. Ohsawa, T. Tokunaga, C. Thomas, A. Ganesan, Y. Masuda, T. Doi
- Organizer
  The 54rd Japanese Peptide Symposium
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 3D structure-based design and synthesis of apratoxin A mimetics2017
- Author(s)
  Y. Onda, Y. Masusa, M. Yoshida, T. Doi
- Organizer
  12th Australian Peptide Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] Spiropreussione A提唱構造の全合成2017
- Author(s)
  塚本裕一，野村友美，藤原広一，土井隆行
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] Piperidamycin F誘導体の合成研究2017
- Author(s)
  吉田将人，高橋優輔，関岡直樹，新家一男，土井隆行
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内キャンパス，仙台
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] Teixobactinの合成研究2017
- Author(s)
  大澤宏祐，徳永拓野，Carys Thomas, A. Ganesan, 増田裕一，土井隆行
- Organizer
  第35回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] スピロママコンAおよび類縁体の合成研究2017
- Author(s)
  塚本裕一，花田祥吾，熊坂幸一，土井隆行
- Organizer
  第43回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] Protein－Protein Interaction Inhibitor Thielocin B12016
- Author(s)
  T. Doi, M. Yoshida, K. Ohsawa, K. Shin-ya, M. Takagi, Y. Uekusa, T. Yamaguchi, K.i Kato, T. Hirokawa, T. Natsume
- Organizer
  Symposium on Foldamers 2016
- Place of Presentation
  IECB, Bordeaux-Pessac, France
- Year and Date
  2016-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] Synthesis and Biological Evaluation of Cyclodepsipeptide Natural Products2016
- Author(s)
  T. Doi
- Organizer
  The 10th International Symposium on Integrated Synthesis (ISONIS-10)
- Place of Presentation
  Awaji Yumebutai International Conference
- Year and Date
  2016-11-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26282208
[Presentation] 環状デプシペプチド天然物の全合成と生物活性評価2016
- Author(s)
  土井隆行
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-27
- Invited
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 海洋シアノバクテリア由来の心筋分化誘導活性物質2016
- Author(s)
  福島弘之，前島寛，魚崎英毅，松尾武彦，吉田将人，恩田勇一，鈴木淳，藤野雄太，増田裕一，八田知久，夏目徹，神平梨絵，坂本匠，新井大祐，堀越直樹，鯨井智也，胡桃坂仁志，伏谷伸宏，土井隆行，山下潤，中尾洋一
- Organizer
  第58回天然有機化合物討論会
- Place of Presentation
  東北大学川内萩ホール
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-26282208
[Presentation] Total Synthesis of Biologically Active Cyclodepsipeptide Natural Product2016
- Author(s)
  Takayuki Doi
- Organizer
  The 12th International Symposium on Organic Reactions (ISOR-12)
- Place of Presentation
  Kyoto Terrsa, Kyoto
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] Synthesis and Biological Evaluation of Cyclodepsipeptide Natural Products2016
- Author(s)
  Takayuki Doi
- Organizer
  The 10th International Symposium on Integrated Synthesis (ISONIS-10)
- Place of Presentation
  Awaji Yumebutai International Conference Center, Hyogo
- Year and Date
  2016-11-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 三次元構造に基づいたApratoxin A ミメティクスの創製2016
- Author(s)
  恩田勇一，増田裕一，吉田将人，土井隆行
- Organizer
  第34回メディシナルケミストリーシンポジウム
- Place of Presentation
  つくば国際会議場
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26282208
[Presentation] Synthetic study for spiruchostatin analogues2015
- Author(s)
  Masahito Yoshida, Koji Umeda, and Takayuki Doi
- Organizer
  平成２７年度化学系学協会東北大会
- Place of Presentation
  弘前大学文京キャンパス
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PUBLICLY-26102709
[Presentation] Total synthesis of cyclodepsipeptide natural products and their biological evaluation2015
- Author(s)
  T. Doi
- Organizer
  PACIFICHEM2015
- Place of Presentation
  Honolulu, Hawai, U.S.A.
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26282208
[Presentation] Combinatorial synthesis and biological evaluation of cyclodepsipeptide destruxin E analogues2015
- Author(s)
  M. Yoshida, Y. Ishida, H. Sato, K. Adachi, H. Murase, H. Nakagawa, T. Doi
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  平塚市中央公民館
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-26282208
[Presentation] 骨吸収抑制作用を示すdestruxin E 類縁体の合成と生物活性評価2015
- Author(s)
  佐藤寛，安達謙太，石田恵崇，村瀬隼人，中川大，吉田将人，土井隆行
- Organizer
  第107回有機合成シンポジウム
- Place of Presentation
  慶應義塾大学薬学部，東京
- Year and Date
  2015-06-09
- Data Source
  KAKENHI-PROJECT-26282208
[Presentation] カイコ麻痺活性を示す環状ペプチドPF1171類の全合成と三次元構造ー活性相関2015
- Author(s)
  増田裕一，田中錬，土井隆行
- Organizer
  第57回天然有機化合物討論会
- Place of Presentation
  神奈川県民ホール
- Year and Date
  2015-09-09
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] Total synthesis of cyclodepsipeptide natural products and their biological evaluation2015
- Author(s)
  T. Doi
- Organizer
  PACIFICHEM2015
- Place of Presentation
  Honolulu, Hawaii
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-15H05837
[Presentation] 骨吸収抑制作用を示す19員環デプシペプチドデストラキシンEの液相全合成2014
- Author(s)
  吉田将人，佐藤寛，石田恵崇，中川大，土井隆行
- Organizer
  日本薬学会第１３４年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] Apratoxin C オキサゾリン誘導体の全合成2014
- Author(s)
  恩田勇一，鈴木淳，吉田将人，増田裕一，土井隆行
- Organizer
  第５３回日本薬学会東北支部大会
- Place of Presentation
  いわき明星大学、福島
- Year and Date
  2014-10-05
- Data Source
  KAKENHI-PROJECT-26282208
[Presentation] アプラトキシンCの活性コンホメーションに着目した構造活性相関研究2014
- Author(s)
  増田裕一，鈴木淳，吉田将人，土井隆行
- Organizer
  日本薬学会第１３４年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] 骨吸収抑制作用を有するデストラキシンEの全合成と構造活性相関研究2013
- Author(s)
  吉田将人，石田恵崇，佐藤寛，竹内久征，村瀬隼人，中川大，土井隆行
- Organizer
  第３９回反応と合成の進歩シンポジウム
- Place of Presentation
  九州大学
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] Synthetic Study of 3-Acyl-4-Quinolones via Lewis base-Catalyzed Tandem Acyl Transfer-Cyclization2013
- Author(s)
  M. Yoshida, K. Saito, T. Doi
- Organizer
  International Conference on the Chemistry of Antibiotics and Other Bioactive Compounds
- Place of Presentation
  Yamanashi
- Data Source
  KAKENHI-PUBLICLY-24106703
[Presentation] 天然物の全合成と機能解明に向けたアプローチ2013
- Author(s)
  土井隆行
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] 生物活性環状デプシペプチド天然物の全合成，誘導体合成，活性評価、機能構造解析2013
- Author(s)
  土井隆行
- Organizer
  第３０回有機合成化学セミナー
- Place of Presentation
  せとうち児島ホテル，岡山
- Invited
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] A Pratial Reduction of α,β-Unsaturated Esters to Aldehydes in Flow2013
- Author(s)
  M. Yoshida, H. Otaka, T. Doi
- Organizer
  International Symposium on Integrated Synthesis 8
- Place of Presentation
  Nara
- Data Source
  KAKENHI-PUBLICLY-24106703
[Presentation] A Selective DIBAL Reduction of α,β-Unsaturated Esters to Aldehydes in Flow2013
- Author(s)
  M. Yoshida, H. Otaka, T. Doi
- Organizer
  International Symposium for the 70th Anniversary of the Tohoku Branch of the Chemical Society of Japan
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PUBLICLY-24106703
[Presentation] Solid-Phase Total Synthesis of Spiruchostatin A2013
- Author(s)
  T. Doi
- Organizer
  International Symposium on Integrated Synthesis 8
- Place of Presentation
  Nara
- Invited
- Data Source
  KAKENHI-PUBLICLY-24106703
[Presentation] 骨吸収抑制作用を有するデストラキシンE の全合成と構造活性相関研究2013
- Author(s)
  吉田将人, 石田恵崇, 佐藤寛, 竹内久征, 村瀬隼人, 中川大, 土井隆行
- Organizer
  第39回反応と合成の進歩シンポジウム
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] Total Synthesis and Conformational Analysis of Apratoxin C2013
- Author(s)
  Y. Masuda, J. Suzuki, M. Yoshida, T. Doi
- Organizer
  APIPS 2013: 4th Asia-Pacific International Peptide Symposium, 50th Japanese Peptide Symposium
- Place of Presentation
  Hotel Hankyu Expo Park, Osaka
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] 生物活性環状デプシペプチド天然物の合成，誘導体合成，活性評価，機能構造解析2013
- Author(s)
  土井隆行
- Organizer
  第30回有機合成セミナー
- Place of Presentation
  岡山
- Invited
- Data Source
  KAKENHI-PUBLICLY-24106703
[Presentation] Solid-phase Total Synthesis od Spiruchostatin A2013
- Author(s)
  Takayuki Doi
- Organizer
  International Symposium on Integrated Synthesis 8
- Place of Presentation
  Nara
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] 天然物の全合成と機能解明に向けたアプローチ2013
- Author(s)
  土井隆行
- Organizer
  日本薬学会第133年会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] Piperidamycin類の全合成研究2012
- Author(s)
  関岡直樹, 高木基樹, 新家一男, 土井隆行
- Organizer
  日本薬学会132年会
- Place of Presentation
  北海道
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] デストラキシンEおよびその誘導体の全合成と生物活性評価2012
- Author(s)
  吉田将人，石田恵崇，竹内久征，中川大，八代田陽子，吉田稔，高木基樹，新家一男，土井隆行
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] 分子内アシル基転位-位置選択的付加による3位アシル置換型フラボノイド類の骨格構築2012
- Author(s)
  吉田将人, 齋藤虹矢, 藤野雄太, 土井隆行
- Organizer
  日本薬学会132年会
- Place of Presentation
  北海道
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PUBLICLY-22106503
[Presentation] デストラキシンE およびその誘導体の全合成と生物活性評価2012
- Author(s)
  吉田将人, 石田恵崇, 竹内久征, 中川大, 八代田陽子, 吉田稔, 高木基樹, 新家一男, 土井隆行
- Organizer
  第49回ペプチド討論会プログラム
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] Development of Lewis Base-Catalyzed Tandem Acyl Transfer-Cyclization: Synthesis of 3-Acylflavone Derivatives2012
- Author(s)
  M. Yoshida, K. Saito, Y. Fujino, T. Doi
- Organizer
  The Twelfth International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-12)
- Place of Presentation
  Kyoto
- Year and Date
  2012-11-12
- Data Source
  KAKENHI-PUBLICLY-24106703
[Presentation] 分子プローブを指向したDestruxin E類縁体の全合成研究および生物活性評価2011
- Author(s)
  吉田将人, 石田恵崇, 竹内久征, 八代田陽子, 吉田稔, 中川大, 高木基樹, 新家一男, 土井隆行
- Organizer
  第50回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] タンパク質間相互作用阻害活性を示すThielocin B1の全合成と相互作用解析2011
- Author(s)
  吉田将人, 大澤宏祐, 高木基樹, 広川貴次, 植草義徳, 加藤晃一, 新家一男, 夏目徹, 土井隆行
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪
- Year and Date
  2011-09-29
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] Total Synthesis of Cyclicdepsipeptide Destruxin E and its Derivatives as a Potent V-ATPase Inhibitor2011
- Author(s)
  M.Yoshida, Y.Ishida, H.Takeuchi, Y.Yashiroda, M.Yoshida, H.Nakagawa, M.Takagi, K.Shinya, T.Doi
- Organizer
  AIMECS11
- Place of Presentation
  東京
- Year and Date
  2011-11-30
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] フラボノイド類の多様性指向型合成(1):o-アルキノイルフェノールに対する位置選択的環化反応の開発2011
- Author(s)
  吉田将人, 藤野雄太, 齋藤虹矢, 土井隆行
- Organizer
  第50回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PUBLICLY-22106503
[Presentation] 位置選択的環化反応を利用したフラボノイド類縁体の合成研究2011
- Author(s)
  吉田将人, 藤野雄太, 齋藤虹矢, 土井隆行
- Organizer
  第100回有機合成シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PUBLICLY-22106503
[Presentation] フラボノイド類の多様性指向型合成(2):連続的転移-環化反応による3位置換型フラボノイド類の骨格構築2011
- Author(s)
  吉田将人, 齋藤虹矢, 藤野雄太, 土井隆行
- Organizer
  第50回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PUBLICLY-22106503
[Presentation] Total Synthesis of Cyclicdepsipeptide Destruxin E and its Derivatives as a Potent V-ATPase Inhibitor2011
- Author(s)
  Masahito Yoshida, Yoshitaka Ishida, Hisayuki Takeuchi, Yoko Yashiroda, Minoru Yoshida, Hiroshi Nakagawa, Motoki Takagi, Kazuo Shin-ya, Takayuki Doi
- Organizer
  AIMECS11
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] 位置選択的環化反応を利用したフラボノイド類の合成研究とフロー合成への応用2011
- Author(s)
  吉田将人, 藤野雄太, 土井隆行
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PUBLICLY-22106503
[Presentation] 遷移金属触媒を用いた分子内炭素-水素結合官能基化プロセスを経由する2-キノロン環構築法の開発2011
- Author(s)
  稲本浄文, 川崎順平, 齋藤孔隆, 廣谷功, 土井隆行
- Organizer
  第50回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2011-10-29
- Data Source
  KAKENHI-PUBLICLY-22106503
[Presentation] タンパク質間相互作用阻害活性を示すThielocin B1 の全合成と相互作用解析2011
- Author(s)
  吉田将人, 大澤宏祐, 高木基樹, 広川貴次, 植草義徳, 加藤晃一 ,新家一男, 夏目徹, 土井隆行
- Organizer
  第53回天然有機化合物討論会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23310145
[Presentation] 環状構造改変型デストラキシンE誘導体の合成と生物活性評価
- Author(s)
  吉田将人，安達謙太，佐藤寛，村瀬隼人，中川大，土井隆行
- Organizer
  日本薬学会第１３５年会
- Place of Presentation
  神戸学院大学、神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26282208
[Presentation] 生物活性環状デプシペプチド天然物の全合成，誘導体合成，活性評価，機能構造解析
- Author(s)
  土井隆行
- Organizer
  平成２６年度化学系学協会東北大会
- Place of Presentation
  山形大学米沢キャンパス、米沢
- Year and Date
  2014-09-20 – 2014-09-21
- Invited
- Data Source
  KAKENHI-PROJECT-26282208
[Presentation] 生物活性環状デプシペプチド天然物の全合成，誘導体合成，活性評価，機能構造解析
- Author(s)
  土井隆行
- Organizer
  平成２６年度化学系学協会東北大会
- Place of Presentation
  山形大学米沢キャンパス、米沢
- Year and Date
  2014-09-20 – 2014-09-21
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102709

1. YAMAMOTO Keiji (80025999)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. TAKAHASHI Takashi (80110724)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
3. YAMADA Haruo (10175664)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SAKURAI Minoru (50162342)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NAKAGAWA Hiroshi (40397039)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ISHIKAWA Toshihisa (60193281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MIYAZAWA Masahiro (70209899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAWAMAMI Yukio (50289302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TANAKA Hiroshi (40334544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Fukase Koichi (80192722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Sugawara Akira (90270834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SAWATUBASHI Shun (70535103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TAKEMOTO Tatsuya (30443899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YAMAMOTO Yasuhiko (20313637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TAKAGI Kiyoshi (80595562)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Sato Horoshi (60215829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Yokoyama Atsushi (20572332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. ITO Ryo (80733815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 安田誠 (40273601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 中田雅久 (50198131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 松原誠二郎 (90190496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 塚本裕一 (70323037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
23. TANAKA Ren

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 増田裕一

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
25. 廣谷功

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. 大澤宏祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 井本正哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 吉田将人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 塚本佐知子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Doi Takayuki 土井 隆行

DOI Takayuki 土井 隆行

Research Projects

Research Products

Co-Researchers

中分子ペプチド創薬を支える高難度ペプチド天然物の全合成技術開発Principal Investigator

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Optimization of flow synthesis reaction conditions and database construction for autonomous organic synthesisPrincipal Investigator

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Optimization of flow synthesis and application to diversed synthesisPrincipal Investigator

Principal Investigator

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Total Synthesis and Drug Discovery Research of Middle Molecular Peptidic Natural ProductsPrincipal Investigator

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Principal Investigator

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Middle-size cyclic peptides containing unnatural amino acids enable the control of higher cell functionPrincipal Investigator

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ヒストン脱アセチル化酵素阻害剤の創製研究Principal Investigator

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Development of drug discovery chemistry centered on cyclodepsipeptide natural productsPrincipal Investigator

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フロー系を用いる骨格形成反応の開発と有機合成の効率化Principal Investigator

Principal Investigator

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Synthesis of biologically acitive natural product cyclodepsipeptides and their analoguesPrincipal Investigator

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フロー系を用いる骨格形成反応の開発研究Principal Investigator

Principal Investigator

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Research Institution

抗癌剤テロメスタチンを母骨格とするヒ合物ライブラリーの合成研究Principal Investigator

Principal Investigator

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Review Section

Doi Takayuki 土井隆行

DOI Takayuki 土井隆行