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HORIUCHI Takahiko  堀内 孝彦

ORCIDConnect your ORCID iD *help
… Alternative Names

堀内 孝彦  ホリウチ タカヒコ

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Researcher Number 90219212
Other IDs
Affiliation (based on the past Project Information) *help 2013 – 2022: 九州大学, 大学病院, 教授
2011 – 2012: 九州大学, 医学(系)研究科(研究院), 准教授
2008 – 2012: Kyushu University, 大学院・医学研究院, 准教授
2009 – 2011: Kyushu University, 医学研究院, 准教授
2008 – 2009: 九州大学, 大学病院, 准教授 … More
2007: 九州大学, 大学院・医学研究院, 講師
2003 – 2007: KYUSHU UNIVERSITY, University Hospital, Assistant Professor, 大学病院, 講師
2006: 九州大学, 大学院医学研究院, 講師
2000 – 2002: 九州大学, 大学院・医学研究院, 助手
1999: Dept of Medicine and Biosystemic Science, Kyushu University, Research associate, 大学院・医学系研究科, 助手
1996 – 1998: 九州大学, 医学部, 助手
1994: 九州大学, 医学部, 助手
1993: 愛媛大学, 医学部, 助手
1991: Ehime University School of Medicine, Assistant Professor, 医学部, 助手
1990: 愛媛大学, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / 内科学一般 / 膠原病・アレルギー・感染症内科学 / Basic Section 52010:General internal medicine-related / General internal medicine(including psychosomatic medicine)
Except Principal Investigator
膠原病・アレルギー・感染症内科学 / 内科学一般 / Basic Section 53020:Cardiology-related / Hygiene / General internal medicine(including psychosomatic medicine) / Epidemiology and preventive medicine / Biological Sciences
Keywords
Principal Investigator
遺伝子解析 / サイトカイン / アポトーシス / TNF / TNF-α / 全身性エリテマトーデス / 補体 / C1インヒビター / 遺伝性血管性浮腫 / プラスミノーゲン … More / 血管性浮腫 / 関節リウマチ / 抗TNF療法 / 細胞内シグナル伝達 / 自己免疫疾患 / DNA / methylation / 抗ウイルス抗体 / 新型コロナ / 高齢者 / DNAメチル化 / COVID-19 / 凝固線溶系 / 接触系 / 全国調査 / ブラジキニン / 窒息 / 浮腫 / 患者レジストリー / cell-cycle arrest / apoptosis / rheumatoid arthritis / anti-TNF therapy / Cytokine / シグナル伝達 / 細胞周期 / Rheumatoid arthritis / Crohn's disease / anti-TNF-αtherapy / cytokine / クローン病 / CD4+ T cell / E-selectm / 炎症 / CD4+ T cells / E-selectin / 膜型TNF-α / deficiency / cgtokine / Complement / 輸送 / 内向きシグナル / cDNA array / 増殖 / TNF阻害薬 / 可溶型TNF / 膜型TNF / CDC / ADCC / 一塩基多型 / 一塩基多型(SNP) / caspase-8 / がん / SLE / 慢性関節リウマチ / SNP / B因子分解産物 / B因子 / トランスジェニック マウス … More
Except Principal Investigator
遺伝子多型 / BAFF / APRIL / BR3 / SLE / 自己免疫疾患 / 関節リウマチ / 国際共同研究 / 交互作用 / 肺がん / polymorphism / TNF family / 疾患感受性遺伝子 / B細胞 / TNFファミリー / 全身性エリテマトーデス / HTLV-1 / TNF-α / 炎症 / 喫煙 / ゲノム疫学 / TNFα / 一塩基多型(SNP) / 一塩基多型 / ドラッグリポジショニング / 金ナノ粒子 / トランスジェニックマウス / ナノテクノロジー / 心不全 / ジスルフィラム / 腹部動脈瘤 / 温熱療法 / 下肢虚血 / 金ナノロッド / 血管新生 / 低酸素 / DNA / 温熱 / 老化 / 生物学的老化 / テロメア / rheumatoid arthritis / svnovial fibroblast-like cells / autoimmune disease / 共刺激 / Furin転換酵素 / 滑膜細胞 / susceptible gene / B cell / cytokine / single nucleotide polymorphisims / genetic analysis / Rheumatoid arthritis / Systemic lupus erythematosus / 慢性関節リウマチ / サイトカイン / 遺伝子解析 / T cell-B cell interaction / TNF-alpha / Okadaic acid / Protein kinase C / Phosphorylation / T cell activation / CD3 / 活性化 / 蛋白リン酸化 / Tリンパ球 / 細胞内Ca^<2+> / シグナル伝達 / Bリンパ球 / 活性化Tリンパ球 / 膜型TNF-α / IgM産生 / オカダ酸 / PMA / リン酸化 / T細胞活性化 / signal transduction / Cytotoxicity / T-cell receptor / Retrovirus / Immunodeficiency / 細胞内カルシウムイオン / 細胞障害性 / HTLVーI / 細胞内情報伝達 / 細胞障害活性 / T細胞受容体 / レトロウイルス / 免疫不全症 / ゲノム疫学 / エストロゲン関連遺伝子 / エストロゲン / TACE / TNF変換酵素 / TNF / 細胞内ドメイン / SPPL / TNF-α変換酵素 / 膜内蛋白分解酵素 / 間葉系幹細胞 / 制御性T細胞 / 強皮症 / 遺伝子発現プロファイル / 移植 / 造血幹細胞 / 純化 / 免疫再構築 / CD34陽性細胞 / 造血幹細胞移植 / Tacrolimus(FK506) / 筋膜炎 / TNFR1 / 周期熱 / TRAPS / DNA除去修復 / 薬物代謝 / 分子疫学 / 社会医学 / 全身性エリテマトーデス(SLE) / ゲノムワイドな関連解析 / ゲノムワイドな確定ハプロタイプ / 胞状奇胎 / ソフトウェア「QSNP lite」 / 高精度アレル頻度決定 / SSCP解析 / CpGアイランド / 家族性滲出性硝子体網膜症 / DHaploDB / 日本人確定ハプロタイプ / プールDNAによるゲノムワイド関連解析 / QSNPlite / 全胞状奇胎 / 確定ハプロタイプ / PLACE-SSCP / 関連解析 / データベース / ハプロタイプ / SSCP / 疾患関連解析 / SNP Less
  • Research Projects

    (33 results)
  • Research Products

    (213 results)
  • Co-Researchers

    (41 People)
  •  Reduction of immunogenicity of SARS-CoV-2 vaccine in the elderly people: analysis by DNA methylationPrincipal Investigator

    • Principal Investigator
      堀内 孝彦
    • Project Period (FY)
      2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Kyushu University
  •  Clarification of the pathogenesis of angioedemaPrincipal Investigator

    • Principal Investigator
      Horiuchi Takahiko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Kyushu University
  •  抗酒癖剤ジスルフィラム含有ナノ粒子による炎症性心不全治療の研究

    • Principal Investigator
      樋口 義洋
    • Project Period (FY)
      2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kyushu University
  •  Local hyperthermia treatment for peripheral arterial disease by using gold nano-rods

    • Principal Investigator
      TOKUNOU Tomotake
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Kyushu University
  •  Clarification of the pathophysiology of hereditary and non-hereditary angioedema by using patient registryPrincipal Investigator

    • Principal Investigator
      Horiuchi Takahiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Kyushu University
  •  The development of aging parameters by serum telomere DNA analysis

    • Principal Investigator
      Maeda Toyoki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Kyushu University
  •  Genome epidemiologic study on lung cancer and estrogen-related genes.

    • Principal Investigator
      Kiyohara Chikako
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Epidemiology and preventive medicine
    • Research Institution
      Kyushu University
  •  Identification of the new function of TNF induced by intramembrane proteases and the application to regulate inflammatory diseases.

    • Principal Investigator
      TSUKAMOTO Hiroshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Kyushu University
  •  Clarification of the mechanisms of intracellular trafficking of TNFPrincipal Investigator

    • Principal Investigator
      HORIUCHI Takahiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Kyushu University
  •  Genome epidemiologic study on lung cancer and inflammation-related genes

    • Principal Investigator
      KIYOHARA Chikako
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Kyushu University
  •  Development of a new stem cell transplantation regimen in the treatment of refractory autoimmune diseases

    • Principal Investigator
      TSUKAMOTO Hiroshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Kyushu University
  •  Immunological function of transmembrane TNF-alphaPrincipal Investigator

    • Principal Investigator
      HORIUCHI Takahiko
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Kyushu University
  •  Functional analysis of BAFF, APRIL and their receptors, and the study of their role in the pathogenesis of autoimmune disease

    • Principal Investigator
      TSUKAMOTO Hiroshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Kyushu University
  •  DEVELOPMENT OF QUANTITATIVE METHODS FOR SINGLE NUCLEOTIDE POLYMORPHISMS ANALYSIS AND ITS APPLICATION IN MEDICAL GENETICS

    • Principal Investigator
      TAHIRA Tomoko, 林 健志
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  Molecular epidemiologic study of lung cancer on interaction between smoking and genetic factors

    • Principal Investigator
      KIYOHARA Chikako
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Kyushu University
  •  本邦初のTRAPS患者の全国大規模疫学調査と診断基準の作成に関する研究

    • Principal Investigator
      井田 弘明
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Nagasaki University
  •  Functional analyses for transmembrane TNF-alphaPrincipal Investigator

    • Principal Investigator
      HORIUCHI Takahiko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      KYUSHU UNIVERCITY
  •  (DNAプール)PLACE‐SSCP法による自己免疫疾患の病因遺伝子の網羅的探索Principal Investigator

    • Principal Investigator
      堀内 孝彦
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  Functional analysis of APRIL and BAFF, and the study of their role in the pathogenesis of autoimmune disease

    • Principal Investigator
      TSUKAMOTO Hiroshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      KYUSHU UNIVERSITY
  •  (DNAプール)PLACE-SSCP法による自己免疫疾患の病因遺伝子の網羅的探索Principal Investigator

    • Principal Investigator
      堀内 孝彦
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  (DNAプール)PLACE-SSCP法による自己免疫疾患の病因遺伝子の網羅的探索Principal Investigator

    • Principal Investigator
      堀内 孝彦
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  The association of the gene polymorphism of APRIL and BAFF with autoimmune diseases : Functional analysis

    • Principal Investigator
      TSUKAINOTO Hiroshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  Analysis of the function of membrane TNF-αPrincipal Investigator

    • Principal Investigator
      HORIUCHI Takahiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Kyushu University
  •  新しい遺伝子多型検出システムを用いた免疫・アレルギー疾患の病因遺伝子の探索Principal Investigator

    • Principal Investigator
      堀内 孝彦
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  がん化におけるcaspase-8機能異常の解析Principal Investigator

    • Principal Investigator
      堀内 孝彦
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  新しい遺伝子多型検出システムによる免疫・アレルギー性疾患の病因遺伝子の解析Principal Investigator

    • Principal Investigator
      堀内 孝彦
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  Functional analysis of membrane TNF-αPrincipal Investigator

    • Principal Investigator
      HORIUCHI Takahiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  Functional analysis of membrane TNF-α on activated T cellsPrincipal Investigator

    • Principal Investigator
      HORIUCHI Takahiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  Biological activity of complement fragment BaPrincipal Investigator

    • Principal Investigator
      HORIUCHI Takahiko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  補体活性化産物Baの自己免疫疾患の発症・進展に及ぼす役割の解析Principal Investigator

    • Principal Investigator
      堀内 孝彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      内科学一般
    • Research Institution
      Kyushu University
  •  補体活性化産物Bbの免疫機構における役割-トランスジェニックマウスによる解析-Principal Investigator

    • Principal Investigator
      堀内 孝彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      内科学一般
    • Research Institution
      Ehime University
  •  Association of the functional impairement of T cells from patients with systemic lupus erythematosus with protein phosphorylation

    • Principal Investigator
      NAGASAWA Kohei
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Saga Medical School
      Kyushu University
  •  Abnormality of signal Transduction via T-cell receptors mediated by retrovirus infection

    • Principal Investigator
      YASUKAWA Masaki
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内科学一般
    • Research Institution
      Ehime University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] リウマチ病学テキスト改訂第3版2022

    • Author(s)
      冨田哲也、堀内孝彦
    • Total Pages
      608
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Book] 小児疾患診療のための病態生理2改訂第6版2021

    • Author(s)
      日浦惇貴, 堀内孝彦
    • Total Pages
      1112
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Book] 原発性免疫不全症候群 最新の疾患分類と新規疾患を中心に2020

    • Author(s)
      堀内孝彦
    • Total Pages
      537
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Book] 小児感染免疫学2020

    • Author(s)
      堀内孝彦
    • Total Pages
      792
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Book] 膠原病・リウマチ・アレルギー 研修ノート2016

    • Author(s)
      塚本浩、堀内孝彦
    • Total Pages
      574
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-16K09246
  • [Book] 補体への招待2011

    • Author(s)
      大井洋之、木下タロウ、松下操、塚本浩堀内孝彦、他
    • Total Pages
      232
    • Publisher
      メジカルレビュー社
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Journal Article] A Missense Mutation of the Plasminogen Gene in a Japanese Family with Hereditary Angioedema with Normal C1 Inhibitor: Third Family Survey in Asia2023

    • Author(s)
      Yakushiji H, Yamagami K, Hashimura C, Iwasaki H, Horiuchi T
    • Journal Title

      Intern. Med.

      Volume: 62 Issue: 13 Pages: 2005-2008

    • DOI

      10.2169/internalmedicine.0645-22

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2023-07-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Journal Article] Immunosuppressive therapy and humoral response to second and third mRNA COVID-19 vaccination in patients with autoimmune rheumatic diseases2023

    • Author(s)
      Kashiwado Y, Kimoto Y, Ohshima S, Sawabe T, Irino K, Nakano S, Hiura J, Yonekawa A, Wang Q, Doi G, Ayano M, Mitoma H, Ono N, Arinobu Y, Niiro H, Hotta T, Kang D, Shimono N, Akashi K, Takeuchi T, Horiuchi T
    • Journal Title

      Rheumatology (Oxford)

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07447
  • [Journal Article] Risk factors for hospitalization or mortality for COVID-19 in patients with rheumatic diseases: Results of a nationwide JCR COVID-19 registry in Japan2022

    • Author(s)
      Oku Kenji、Kimoto Yasutaka、Horiuchi Takahiko、Yamamoto Mari、Kondo Yasushi、Okamoto Masashi、Atsumi Tatsuya、Takeuchi Tsutomu
    • Journal Title

      Modern Rheumatology

      Volume: online ahead Issue: 4 Pages: 768-776

    • DOI

      10.1093/mr/roac104

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08792, KAKENHI-PROJECT-22K07447
  • [Journal Article] The complement system and ANCA associated vasculitis in the era of anti-complement drugs2022

    • Author(s)
      Kimoto Y, Horiuchi T
    • Journal Title

      Front. Immunol.

      Volume: 23

    • DOI

      10.3389/fimmu.2022.926044

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Journal Article] Antibody response to SARS-CoV-2 mRNA vaccines in patients with rheumatic diseases in Japan: Interim analysis of a multicentre cohort study2022

    • Author(s)
      Kashiwado Yusuke、Kimoto Yasutaka、Sawabe Takuya、Irino Kensuke、Nakano Shota、Hiura Junki、Wang Qiaolei、Kawano Shotaro、Ayano Masahiro、Mitoma Hiroki、Ono Nobuyuki、Arinobu Yojiro、Niiro Hiroaki、Hotta Taeko、Kang Dongchon、Akashi Koichi、Ohshima Shiro、Takeuchi Tsutomu、Horiuchi Takahiko
    • Journal Title

      Modern Rheumatology

      Volume: 33 Issue: 2 Pages: 367-372

    • DOI

      10.1093/mr/roac030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07447
  • [Journal Article] Clinical course of patients with rheumatoid arthritis who continue or discontinue biologic therapy after hospitalization for infection: a retrospective observational study2022

    • Author(s)
      Kashiwado Y, Kiyohara C, Kimoto Y, Nagano S, Sawabe T, Oryoji K, Mizuki S, Nishizaka H, Yoshizawa S, Yoshizawa S, Tsuru T, Inoue Y, Ueda N, Ota SI, Suenaga Y, Miyamura T, Tada Y, Niiro H, Akashi K, Horiuchi T
    • Journal Title

      Arthritis Res. Ther.

      Volume: 24 Issue: 1

    • DOI

      10.1186/s13075-022-02820-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Journal Article] COVID-19と補体2022

    • Author(s)
      日浦淳貴、堀内孝彦
    • Journal Title

      日本臨牀

      Volume: 80 Pages: 1854-1858

    • Data Source
      KAKENHI-PROJECT-22K07447
  • [Journal Article] Hot spring bathing is associated with a lower prevalence of hypertension among Japanese older adults: a cross-sectional study in Beppu.2022

    • Author(s)
      Yamasaki S, Tokunou T, Maeda T, Horiuchi T.
    • Journal Title

      Sci Rep.

      Volume: 12 Issue: 1 Pages: 19462-19462

    • DOI

      10.1038/s41598-022-24062-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K12887, KAKENHI-PROJECT-18K08041
  • [Journal Article] Clinical and genetic features of hereditary angioedema with and without C1-inhibitor (C1-INH) deficiency in Japan2021

    • Author(s)
      Hashimura C, Kiyohara C, Fukushi J-I, Hirose T, Ohsawa I, Tahira T, Horiuchi T
    • Journal Title

      Allergy

      Volume: 76 Issue: 11 Pages: 3529-3534

    • DOI

      10.1111/all.15034

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Journal Article] Methotrexate Enhances Apoptosis of Transmembrane TNF-Expressing Cells Treated With Anti-TNF Agents2020

    • Author(s)
      Wang Q, Oryoji D, Mitoma H, Kimoto Y, Koyanagi M, Yokoyama K, Ayano M, Akahoshi M, Arinobu Y, Niiro H, Akashi K, Horiuchi T.
    • Journal Title

      Front Immunol.

      Volume: 14 Pages: 2042-2042

    • DOI

      10.3389/fimmu.2020.02042

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17887, KAKENHI-PROJECT-19H03564
  • [Journal Article] Shoulder ultrasound and serum lactate dehydrogenase predict inadequate response to glucocorticoid treatment in patients with polymyalgia rheumatica.2020

    • Author(s)
      Ayano M, Arinobu Y, Tsukamoto H, Ota SI, Misaki K, Nishimura K, Kimoto Y, Mitoma H, Akahoshi M, Akashi K, Horiuchi T, Niiro H.
    • Journal Title

      Rheumatology International

      Volume: - Issue: 7 Pages: 1101-1109

    • DOI

      10.1007/s00296-020-04512-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K19599, KAKENHI-PROJECT-19K08910, KAKENHI-PROJECT-19K17887, KAKENHI-PROJECT-19H03564
  • [Journal Article] Generation of a novel CD30 + B cell subset producing GM-CSF and its possible link to the pathogenesis of systemic sclerosis2020

    • Author(s)
      Higashioka K, Kikushige Y, Ayano M, Kimoto Y, Mitoma H, Kikukawa M, Akahoshi M, Arinobu Y, Horiuchi T, Akashi K, Niiro H.
    • Journal Title

      Clin Exp Immunol.

      Volume: 201 Issue: 3 Pages: 233-243

    • DOI

      10.1111/cei.13477

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K17887, KAKENHI-PROJECT-16H06391, KAKENHI-PROJECT-19H03687, KAKENHI-PROJECT-18K08410, KAKENHI-PROJECT-19H03564
  • [Journal Article] A novel C1 inhibitor gene mutation in a family with hereditary angioedema: Use of genetic analysis to facilitate early diagnosis2020

    • Author(s)
      Yokoyama K, Horiuchi T, Hashimura C, Yoshida A
    • Journal Title

      Allergol. Int.

      Volume: 69 Issue: 1 Pages: 148-149

    • DOI

      10.1016/j.alit.2019.07.005

    • NAID

      130007788671

    • ISSN
      1323-8930, 1440-1592
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Journal Article] Homeostatic Milieu Induces Production of Deoxyribonuclease 1-like 3 from Myeloid Cells.2020

    • Author(s)
      Inokuchi S, Mitoma H, Kawano S, et. al.
    • Journal Title

      J Immunol.

      Volume: 204 Issue: 8 Pages: 2088-2097

    • DOI

      10.4049/jimmunol.1901304

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08910, KAKENHI-PROJECT-19K17887, KAKENHI-PROJECT-19H03564
  • [Journal Article] Hereditary Angioedema Type 1 with Recurrent Dizziness2019

    • Author(s)
      Ando T, Torii R, Kazuta T, Endo T, Araki A, Horiuchi T, Terao S, Katsuno M
    • Journal Title

      Intern. Med.

      Volume: 58 Issue: 13 Pages: 1961-1963

    • DOI

      10.2169/internalmedicine.2015-18

    • NAID

      130007672114

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2019-07-01
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Journal Article] Functional analysis of a novel G87V TNFRSF1A mutation in patients with TNF receptor-associated periodic syndrome2019

    • Author(s)
      Tsuji, S. Matsuzaki, H. Iseki, M. Nagasu, A. Hirano, H. Ishihara, K. Ueda, N. Honda, Y. Horiuchi, T. Nishikomori, R. Morita, Y. Mukai, T.
    • Journal Title

      Clin Exp Immunol

      Volume: 198 Issue: 3 Pages: 416-429

    • DOI

      10.1111/cei.13365

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08299, KAKENHI-PROJECT-19K08923, KAKENHI-PROJECT-19K08943, KAKENHI-PROJECT-19H03564
  • [Journal Article] Accumulation of gold nano-rods in the failing heart of transgenic mice with the cardiac-specific expression of TNF-α2019

    • Author(s)
      Yoshihiro Higuchi, Takuro Niidome, Yuji Miyamoto, Yoshihiro Komohara, Tomotake Tokunou, Toru Kubota, Takahiko Horiuchi
    • Journal Title

      Heart and Vessels

      Volume: 34 Issue: 3 Pages: 538-544

    • DOI

      10.1007/s00380-018-1241-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08041
  • [Journal Article] CCR6+ group 3 innate lymphoid cells accumulate in inflamed joints in rheumatoid arthritis and produce Th17 cytokines2019

    • Author(s)
      Takaki-Kuwahara Ayako、Arinobu Yojiro、Miyawaki Kohta、Yamada Hisakata、Tsuzuki Hirofumi、Irino Kensuke、Ayano Masahiro、Kimoto Yasutaka、Mitoma Hiroki、Akahoshi Mitsuteru、Tsukamoto Hiroshi、Horiuchi Takahiko、Niiro Hiroaki、Akashi Koichi
    • Journal Title

      Arthritis Research & Therapy

      Volume: 21 Issue: 1 Pages: 198-198

    • DOI

      10.1186/s13075-019-1984-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08410, KAKENHI-PROJECT-19K08910, KAKENHI-PROJECT-19K17887, KAKENHI-PROJECT-19H03564
  • [Journal Article] Hereditary angioedema: Repeated attacks in a 10-year-old boy.2019

    • Author(s)
      Ando T, Torii R, Kazuta T, Endo T, Araki A, Horiuchi T, Terao S, Katsuno M
    • Journal Title

      Pediatr. Int.

      Volume: 61 Issue: 1 Pages: 101-103

    • DOI

      10.1111/ped.13729

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Journal Article] CD34-selected versus unmanipulated autologous hematopoietic stem cell transplantation in the treatment of severe systemic sclerosis: a post hoc analysis of a phase I/II clinical trial conducted in Japan.2019

    • Author(s)
      Ayano M, Tsukamoto H, Mitoma H, Kimoto Y, Akahoshi M, Arinobu Y, Miyamoto T, Horiuchi T, Niiro H, Nagafuji K, Harada M, Akashi K
    • Journal Title

      Arthritis Res Ther.

      Volume: 21 Issue: 1 Pages: 30-30

    • DOI

      10.1186/s13075-019-1823-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09897, KAKENHI-PROJECT-16K09898, KAKENHI-PROJECT-16K19603, KAKENHI-PROJECT-18K08410, KAKENHI-PROJECT-19H03564
  • [Journal Article] Hereditary angioedema from 1888 to 2018;Progress and Problems2018

    • Author(s)
      Horiuchi T
    • Journal Title

      Intern Med

      Volume: 57 Pages: 3065-3066

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09246
  • [Journal Article] A missense mutation of the plasminogen gene in hereditary angioedema with normal C1 inhibitor in Japan2018

    • Author(s)
      Yakushiji H, Hashimura C, Fukuoka K, Kaji A, Miyahara H, Kaname S, Horiuchi T
    • Journal Title

      Allergy

      Volume: 73 Pages: 2244-2247

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09246
  • [Journal Article] Molecular mechanisms of action of anti-TNF-α agents - Comparison among therapeutic TNF-α antagonists.2018

    • Author(s)
      Mitoma H, Horiuchi T, Tsukamoto H, Ueda N
    • Journal Title

      Cytokine

      Volume: 101 Pages: 56-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09246
  • [Journal Article] Preventive and promotive effects of habitual hot spa-bathing on the elderly in Japan2017

    • Author(s)
      Maeda T, Mimori K, Suzuki S, Horiuchi T, Makino N.
    • Journal Title

      Sci Rep

      Volume: 8 Issue: 1 Pages: 133-141

    • DOI

      10.1038/s41598-017-18488-3

    • NAID

      130007664970

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08919
  • [Journal Article] A novel scoring system based on common laboratory tests predicts the efficacy of TNF-inhibitor and IL-6 targeted therapy in patients with rheumatoid arthritis: a retrospective, multicenter observational study2017

    • Author(s)
      Nakagawa J, Koyama Y, Kawakami A, Ueki Y, Tsukamoto H, Horiuchi T, Nagano S, Uchino A, Ota T, Akahoshi M, Akashi K
    • Journal Title

      Arthritis Res. Ther

      Volume: 19 Pages: 185-185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09246
  • [Journal Article] クインケ浮腫(血管性浮腫)の診断と治療2017

    • Author(s)
      前田豊樹、堀内孝彦
    • Journal Title

      呼吸器内科

      Volume: 31 Pages: 214-220

    • Data Source
      KAKENHI-PROJECT-16K09246
  • [Journal Article] Clinical and anti-aging effect of mud-bathing therapy for patients with fibromyalgia2017

    • Author(s)
      Maeda T, Kudo Y, Horiuchi T, Makino N.
    • Journal Title

      Mol Cell Biochem

      Volume: - Issue: 1-2 Pages: 87-92

    • DOI

      10.1007/s11010-017-3233-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08919
  • [Journal Article] The epigenetic status of subtelomere of peripheral leukocytes corresponds to cardiographic parameters with a gender association.2017

    • Author(s)
      Maeda T, Horiuchi T, Makino N.
    • Journal Title

      Geriatr Gerontol Int 印刷中

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08919
  • [Journal Article] 線維筋痛症患者の自宅人工炭酸浴による臨床検査値変化の検討2016

    • Author(s)
      前田豊樹、牧野直樹、前川真貴子、木本泰孝、堀内孝彦
    • Journal Title

      九州リウマチ

      Volume: 36 Pages: 83-89

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08919
  • [Journal Article] CYP2E1 rs2031920, COMT rs4680 polymorphisms, cigarette smoking, alcohol use, and lung cancer risk in a Japanese population.2016

    • Author(s)
      Kakino K, Kiyohara C, Horiuchi T, Nakanishi Y
    • Journal Title

      Asian Pac J Cancer Prev

      Volume: 17 Pages: 4063-4070

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293143
  • [Journal Article] Clinical and regulatory perspectives on biosimilar therapies and intended copies of biologics in rheumatology.2016

    • Author(s)
      Mysler E, Pineda C, Horiuchi T, Singh E, Mahgoub E, Coindreau J, Jacobs I
    • Journal Title

      Rheumatol. Int.

      Volume: 36 Pages: 613-625

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09246
  • [Journal Article] Complement-targeted therapy: development of C5- and C5a-targeted inhibition.2016

    • Author(s)
      Horiuchi T, Tsukamoto H
    • Journal Title

      Inflammation Regeneration

      Volume: 36 Pages: 11-11

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K09246
  • [Journal Article] Clinical and genetic features of patients with TNFRSF1A variants in Japan: Findings of a nationwide survey.2016

    • Author(s)
      Ueda N, Ida H, Washio M, Miyahara H, Tokunaga S, Tanaka F, Takahashi H, Kusuhara K, Ohmura K, Nakayama M, Ohara O, Nishikomori R, Minota S, Takei S, Fujii T, Ishigatsubo Y, Tsukamoto H, Tahira T, Horiuchi T
    • Journal Title

      Arthritis Rheumatol.

      Volume: 68 Pages: 2760-2771

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09246
  • [Journal Article] Molecular mechanisms of action of anti-TNF-α agents - Comparison among therapeutic TNF-α antagonists.2016

    • Author(s)
      Mitoma H, Horiuchi T, Tsukamoto H, Ueda N
    • Journal Title

      Cytokine

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09246
  • [Journal Article] Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis.2015

    • Author(s)
      Tanaka A, Tsukamoto H, Mitoma H, Kiyohara C, Ueda N, Ayano M, Ohta S, Kimoto Y, Akahoshi M, Arinobu Y, Niiro H, Tada Y, Horiuchi T and Akashi K.
    • Journal Title

      Arthritis research & therapy

      Volume: 17 Issue: 1 Pages: 27-27

    • DOI

      10.1186/s13075-015-0547-z

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591465, KAKENHI-PROJECT-15K09527, KAKENHI-PROJECT-15K09528
  • [Journal Article] Genetic polymorphisms involved in the inflammatory response and lung cancer risk : a case-control study in Japan2014

    • Author(s)
      Kiyohara C, Horiuchi T, Takayama K, Nakanishi Y
    • Journal Title

      Cytokine

      Volume: 65(1) Pages: 88-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] the Kyushu Sapporo SLE (KYSS) Study Group : The modifying effect of NAT2 genotype on the association between systemic lupus erythematosus and consumption of alcohol and caffeine-rich beverages2014

    • Author(s)
      Kiyohara C, Washio M, Horiuchi T, Asami T, Ide S, Atsumi T, Kobashi G, Takahashi H, Tada Y
    • Journal Title

      Arthritis Care Res(Hoboken)

      Volume: (Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Genetic polymorphisms involved in the inflammatory response and lung cancer risk: a case-control study in Japan2014

    • Author(s)
      Kiyohara C, Horiuchi T, Takayama K, Nakanishi Y
    • Journal Title

      Cytokine

      Volume: 65 Issue: 1 Pages: 88-94

    • DOI

      10.1016/j.cyto.2013.09.015

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591464, KAKENHI-PROJECT-25293143
  • [Journal Article] Reduced carotid intima-media thickness in systemic lupus erythematosus patients treated with cyclosporine A2014

    • Author(s)
      Oryoji K, Kiyohara C, Horiuchi T, Tsukamoto H, Niiro H, Shimoda T, Akashi K, Yanase T
    • Journal Title

      Mod Rheumatol

      Volume: 24 Pages: 86-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Evaluation of the extent of ground-glass opacity on high-resolution CT in patients with interstitial pneumonia associated with systemic sclerosis: Comparison between quantitative and qualitative analysis.2014

    • Author(s)
      Yabuuchi H, Matsuo Y, Tsukamoto H, Horiuchi T, Sunami S, Kamitani T, Jinnouchi M, Nagao M, Akashi K and Honda H.
    • Journal Title

      Clinical radiology

      Volume: 69 Issue: 7 Pages: 758-64

    • DOI

      10.1016/j.crad.2014.03.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591465
  • [Journal Article] Prevalence and risk factors of vertebral fracture in Japanese females with systemic lupus erythematosus2013

    • Author(s)
      Furukawa M, Kiyohara C, Horiuchi T, Tsukamoto H, Mitoma H, Kimoto Y, Uchino A, Nakagawa M, Oryoji K, Shimoda T, Harada M, Akashi K
    • Journal Title

      Mod. Rheumatol

      Volume: 23 Issue: 4 Pages: 765-773

    • DOI

      10.1007/s10165-012-0735-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464, KAKENHI-PROJECT-24591465
  • [Journal Article] Prevalence and risk factors of vertebral fracture in Japanese females with systemic lupus erythematosus2013

    • Author(s)
      Furukawa M, Kiyohara C, Horiuchi T, Tsukamoto H, Mitoma H, Kimoto Y, Uchino A, Nakagawa M, Oryoji K, Shimoda T, Harada M, Akashi K
    • Journal Title

      Mod. Rheumatol

      Volume: 23(4) Pages: 765-773

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in Japan: a review of the literature.2013

    • Author(s)
      Washio M, Nakano T, Kawaguchi Y, Takagi K, Kiyohara C, Tsukamoto H, Tokunaga S, Horiuchi T.
    • Journal Title

      Mod Rheumatol

      Volume: 23 Pages: 210-7

    • DOI

      10.1007/s10165-012-0737-3

    • NAID

      10031167691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591465
  • [Journal Article] The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factor α.2013

    • Author(s)
      Ueda N, Tsukamoto H, Mitoma H, Ayano M, Tanaka A, Ohta S, Inoue Y, Arinobu Y, Niiro H, Akashi K, Horiuchi T.
    • Journal Title

      Inflamm Bowel Dis.

      Volume: 19 Issue: 6 Pages: 1224-1231

    • DOI

      10.1097/mib.0b013e318280b169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591463, KAKENHI-PROJECT-23591464, KAKENHI-PROJECT-24591450, KAKENHI-PROJECT-24591465
  • [Journal Article] The cytotoxic effects of certolizumab pegol and golimumab mediated by transmembrane tumor necrosis factorα2013

    • Author(s)
      Ueda N, Tsukamoto H, Mitoma H, Ayano M, Tanaka A, Ohta S-I, Inoue Y, Arinobu Y, Niiro H, Akashi K, Horiuchi T
    • Journal Title

      Inflamm. Bowel Dis

      Volume: 19(6) Pages: 1224-1231

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] FCGR3A-158 polymorphism influences the biological response to infliximab in Crohn's disease through affecting the ADCC activity2013

    • Author(s)
      Moroi R, Endo K, Kinouchi Y, Shiga H, Kakuta Y, Kuroha M, Kanazawa Y, Shimodaira Y, Horiuchi T,Takahashi S, Shimosegawa T
    • Journal Title

      Immunogenetics

      Volume: 65(4) Pages: 265-271

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] FCGR3A-158 polymorphism influences the biological response to infliximab in Crohn’s disease through affecting the ADCC activity2013

    • Author(s)
      Moroi R, Endo K, Kinouchi Y, Shiga H, Kakuta Y, Kuroha M, Kanazawa Y, Shimodaira Y, Horiuchi T, Takahashi S, Shimosegawa T
    • Journal Title

      Immunogenetics

      Volume: 65 Issue: 4 Pages: 265-271

    • DOI

      10.1007/s00251-013-0679-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Reduced carotid intima-media thickness in systemic lupus erythematosus patients treated with cyclosporine A.2013

    • Author(s)
      Oryoji K, Kiyohara C, Horiuchi T, Tsukamoto H, Niiro H, Shimoda T, Akashi K, Yanase T
    • Journal Title

      Mod Rheumatol

      Volume: 24 Issue: 1 Pages: 86-92

    • DOI

      10.3109/14397595.2013.852838

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591450, KAKENHI-PROJECT-24591465
  • [Journal Article] Sorting nexin 19 regulates the number of sense core vesicles in pancreatic ss-cells2012

    • Author(s)
      Harashima S-I, Horiuchi T, et al.
    • Journal Title

      J Diabetes Invest

      Volume: 3 Pages: 52-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Serum progranulin levels are elevated in patients with systemic lupus erythematosus,reflecting disease activity2012

    • Author(s)
      Tanaka A, Tsukamoto H, Mitoma H, Kiyohara C, Ueda N, Ayano M, Ohta SI, Inoue Y, Arinobu Y, Niiro H, Horiuchi T, Akashi K
    • Journal Title

      Arthritis Res. Ther

      Volume: (Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Risk modification by CYP1A1 and GSTM1 polymorphisms in the association of cigarette smoking and systemic lupus erythematosus in a Japanese population2012

    • Author(s)
      Kiyohara C, Washio M, Horiuchi T, et al.
    • Journal Title

      Scand J Rheumatol

      Volume: 41 Pages: 103-109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells2012

    • Author(s)
      Niiro H,…, Tsukamoto H, et al(16名中12番目)
    • Journal Title

      Blood

      Volume: 119 Issue: 10 Pages: 2263-2273

    • DOI

      10.1182/blood-2011-04-351965

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266, KAKENHI-PROJECT-24590944, KAKENHI-PROJECT-24591450, KAKENHI-PROJECT-24591465
  • [Journal Article] Cigarette smoking, alcohol consumption and the risk of systemic lupus erythematosus: a case-control study in a Japanese population2012

    • Author(s)
      Kiyohara C, Washio M, Horiuchi T, et al.
    • Journal Title

      J Rheumatol

      Volume: 39 Pages: 1367-1370

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Risk modification by CYP1A1 and GSTM1 polymorphisms in the association of cigarette smoking and systemic lupus erythematosus in a Japanese population2012

    • Author(s)
      Kiyohara C, Washio M, Horiuchi T, Tada Y, Asami T, Ide S, Atsumi T, Kobashi G, Takahashi H, and the Kyushu Sapporo SLE (KYSS) Study Group
    • Journal Title

      Scand. J. Rheumatol

      Volume: 41(2) Pages: 103-109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Guideline for Hereditary Angioedema (HAE) 2010 by the Japanese Association for Complement Research2012

    • Author(s)
      Horiuchi T, Ohi H, Ohsawa I, Fujita T, Matsushita M, Okada N, Seya T, Yamamoto T, Endo Y, Hatanaka M, Wakamiya N, Mizuno M, Nakao M, Okada H, Tsukamoto H, Matsumoto M, Inoue N, Nonaka M, Kinoshita T
    • Journal Title

      Allergol. Int

      Volume: 61(4) Pages: 559-562

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells2012

    • Author(s)
      Niiro H, Jabbarzadeh-Tabrizi S, Kikushige Y, Shima T, Noda K, Ota S-I, Tsuzuki H, Inoue Y, Arinobu Y, Iwasaki H, Shimoda S, Baba E, Tsukamoto H, Horiuchi T, Taniyama T, Akashi K
    • Journal Title

      Blood

      Volume: 119(10) Pages: 2263-2273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Clinical factors to predict a poor prognosis and refractory disease in patients with polymyositis and dermatomyositis associated with interstitial lung disease2012

    • Author(s)
      Tada Y, Suematsu E, Ueda A, Nagano S, Sawabe T, Nishizaka H, and Horiuchi T
    • Journal Title

      Clin. Exp. Rheumatol

      Volume: 30(3) Pages: 450-450

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] CIN8s is required for Cbl-mediated regulation of antigen receptor signaling in human B cells2012

    • Author(s)
      Niiro H, JabbarzadehTabrizi S, Kikushige Y, Shima T, Neda K, eta S, Tsuzuki H, Inoue Y, Arinobu Y, Iwasaki H, Shimoda S, Baba E, Tsukamoto H, Horiuchi T, Taniyama T, and Akashi K.
    • Journal Title

      Blood

      Volume: 119 Pages: 2263-2273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Journal Article] Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity.2012

    • Author(s)
      Tanaka A, Tsukamoto H, Mitoma H, Kiyohara C, Ueda N, Ayano M, Ohta SI, Inoue Y, Arinobu Y, Niiro H, Horiuchi T, Akashi K.
    • Journal Title

      Arthritis Res Ther.

      Volume: 14 Issue: 6

    • DOI

      10.1186/ar4087

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591463, KAKENHI-PROJECT-24591465
  • [Journal Article] A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese2012

    • Author(s)
      Okada Y, Shimane K, Kochi Y, Tahira T, Suzuki A, Higasa K, Takahashi A, Horita T, Atsumi T, Ishii T, Okamoto A, Fujio K, Hirakata M, Amano H, Kondo Y, Ito S, Takada K, Mimori A, Saito K, Kamachi M, Kawaguchi Y, Ikari K, Mohammed OW, Matsuda K, Terao C, Ohmura K, Myouzen K, Hosono N, Tsunoda T, Nishimoto N, Mimori T, Matsuda F, Tanaka Y, Sumida T, Jamanaka H, Takasaki Y, Koike T, Horiuchi T, Hayashi K, Kubo M, Kamatani N, Yamada R, Nakamura Y, Yamamoto K
    • Journal Title

      PLoS Genetics

      Volume: 8(1)

    • NAID

      120005906866

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells2012

    • Author(s)
      Niiro H, Jabbarzadeh-Tabrizi S, Horiuchi T, et al.
    • Journal Title

      Blood

      Volume: 119 Pages: 2263-2273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Hereditary angioedema in Japan: Genetic analysis of 13 unrelated cases2012

    • Author(s)
      Yamamoto T, Horiuchi T, et al.
    • Journal Title

      Am J Med Sci

      Volume: 343 Pages: 210-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Genetic polymorphisms involved in carcinogen metabolism and DNA repair and lung cancer risk in a Japanese population2012

    • Author(s)
      Kiyohara C, Horiuchi T, Takayama K, Nakanishi Y
    • Journal Title

      J Thorac Oncol

      Volume: 7 Issue: 6 Pages: 954-962

    • DOI

      10.1097/jto.0b013e31824de30f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390190
  • [Journal Article] Cigarette smoking, alcohol consumption and the risk of systemic lupus erythematosus : a case-control study in a Japanese population2012

    • Author(s)
      Kiyohara C, Washio M, Horiuchi T, Tada Y, Asami T, Ide S, Atsumi T, Kobashi G, Takahashi H, and the Kyushu Sapporo SLE (KYSS) Study Group
    • Journal Title

      J. Rheumatol

      Volume: 39(7) Pages: 1367-1370

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Hereditary angioedema in Japan : Genetic analysis of 13 unrelated cases2012

    • Author(s)
      Yam amoto T, Horiuchi T, Miyahara H, Yoshizawa S, Maehara J, Shono E, Takamura K, Machida H, Tsujioka K, Kaneko T, Uemura N, Suzawa K, Inagaki N, Umegaki N, Kasamatsu Y, Hara A, Arinobu Y, Inoue Y, Niiro H, Kashiwagi Y, Harashima SI, Tahira T, Tsukamoto H, Akashi K
    • Journal Title

      Am. J. Med. Sci

      Volume: 343(3) Pages: 210-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Hereditary Angioedema in Japan: Genetic Analysis of 13 Unrelated Cases2012

    • Author(s)
      Yamamoto, T. Horiuchi, T. Miyahara, H. Yoshizawa, S. Inagaki, N. Umegaki, N. Kasamatsu, Y. Hara, A. Arinobu, Y. Inoue, Y. Niiro, H. Tsukamoto, H. Akashi, K.
    • Journal Title

      Am J Med Sci

      Volume: 343 Issue: 3 Pages: 210-214

    • DOI

      10.1097/maj.0b013e31822bdb65

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591465
  • [Journal Article] Therapeutic response of patients with adult Still's disease to biologic agents; multicenter results in Japan2012

    • Author(s)
      Suematsu R, Ohta A, Matsuura E, Takahashi H, Fujii T, Horiuchi T, Minota S, Ishigatsubo Y, Ota T, Takei S, Soejima S, Inoue H, Koarada S, Tada Y, Nagasawa K
    • Journal Title

      Mod. Rheumatol

      Volume: 22(5) Pages: 712-719

    • NAID

      10031027786

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Hereditary Angioedema in Japan : Genetic Analysis of 13 Unrelated Cases2011

    • Author(s)
      Yamamoto T, Horiuchi T, Miyahara H, Yoshizawa S, Maehara J, Shono E, Takamura K, Machida H, Tsujioka K, Kaneko T, Uemura N, Suzawa K, Inagaki N, Umegaki N, Kasamatsu Y, Hara A, Arinobu Y, Inoue Y, Niiro H, Kashiwagai Y, Harashima SI, Tahira T, Tsukamoto H
    • Journal Title

      Am J Med Sci

      Volume: 342 Pages: 210-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Journal Article] Prevalence of and risk factors for low bone mineral density in Japanese female patients with systemic lupus erythematosus2011

    • Author(s)
      Furukawa M, Kiyohara C, Tsukamoto H, Mitoma H, Kimoto Y, Uchino A, Nakagawa M, Oryoji K, Shimoda T, Akashi K, Harada M, Horiuchi T.
    • Journal Title

      Rheumatol Int

      Volume: 31 Pages: 365-76

    • NAID

      120004951587

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Journal Article] PCP 4 regulates neurite outgrowth2011

    • Author(s)
      Harashima S, Wang Y, Horiuchi T, et al.
    • Journal Title

      J. Neurosci. Res.

      Volume: 89 Pages: 1519-1530

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Role of the MICA polymorphism in systemic lupus erythematosus2011

    • Author(s)
      Yoshida K, Komai K, Shiozawa K, Mashida A, Horiuchi T, Tanaka Y, Nose M, Hashiramoto A, Shiozawa S
    • Journal Title

      Arthritis Rheum

      Volume: 63(10) Pages: 3058-3066

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Analysis of immune re constitution after autologous CD34+ stem/progenitor cell transplantation for systemic sclerosis2011

    • Author(s)
      Tsukamoto H, Nagafuji K, Horiuchi T, Mitoma H, Niiro H, Arinobu Y, Inoue Y, To K, Miyamoto T, Iwasaki H, Teshima T, Harada M, Akashi K.
    • Journal Title

      predominant reconstitution of Th1 CD4+ T cells. Rheumatology

      Volume: 50 Pages: 944-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Journal Article] Immune reconstitution after PBSCT for SSc2011

    • Author(s)
      Tsukamoto H, Nagafuji K, Horiuchi T, et al.
    • Journal Title

      Rheumatology

      Volume: 50 Pages: 944-952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Methylenetetrahydrofolate reductase polymorphisms and interaction with smoking and alcohol consumption in lung cancer risk : a case-control study in a Japanese population2011

    • Author(s)
      Kiyohara C, Horiuchi T, Takayama K, Nakanishi Y
    • Journal Title

      BMC Cancer

      Volume: 11 Pages: 459-468

    • NAID

      120005133102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Correlation between pretreatment or follow-up CT findings and therapeutic effect of autologous peripheral blood stem cell transplantation for interstitial pneumonia associated with systemic sclerosis2011

    • Author(s)
      Yabuuchi H, Matsuo Y, Tsukamoto H, Sunami S, Kamitani T, Sakai S, Hatakenaka M, Nagafuji K, Horiuchi T, Harada M, Akashi K, Honda H
    • Journal Title

      Eur. J. Radiol

      Volume: 79(2)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Analysis of immune reconstitution after autologous CD34+ stem/progenitor cell transplantation for systemic sclerosis : predominant reconstitution of Th1 CD4+ T cells2011

    • Author(s)
      Tsukamoto H, Nagafuji K, Horiuchi T, et al
    • Journal Title

      Rheumatology

      Volume: 50 Pages: 944-952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Journal Article] MTHF reductase polymorphism2011

    • Author(s)
      Kiyohara C, Horiuchi T, et al.
    • Journal Title

      BMC Cancer

      Volume: 11 Pages: 459-468

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Correlation between pretreatment or follow-up CT findings and therapeutic effect of autologous peripheral blood stem cell transplantation for interstitial pneumonia associated with systemic sclerosis2011

    • Author(s)
      Yabuuchi H, Matsuo Y, Tsukamoto H, Sunami S, Kamitani T, Sakai S, Hatakenaka M, Nagafuji K, Horiuchi T, Harada M, Akashi K, Honda H.
    • Journal Title

      Eur J Radiol

      Volume: 79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Journal Article] CT findings of AutoPBSCT for SSc2011

    • Author(s)
      Yabuuchi H, Matsuo Y, Horiuchi T, et al.
    • Journal Title

      Eur. J. Radiol.

      Volume: 79 Pages: 74-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Prevalence of and risk factors for low BMD in SLE2011

    • Author(s)
      Furukawa M, Horiuchi T, et al.
    • Journal Title

      Rheumatol. Int.

      Volume: 31 Pages: 365-376

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Purkinje cell protein 4 positively regulates neurite outgrowth and neurotransmitter release2011

    • Author(s)
      Harashima S, Wang Y, Horiuchi T, Seino Y, Inagaki N
    • Journal Title

      J. Neurosci. Res

      Volume: 89(10) Pages: 1519-1530

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Analysis of immune reconstitution after autologous CD34+ stem/progenitor cell transplantation for systemic sclerosis : predominant reconstitution of Th1 CD4+ T cells2011

    • Author(s)
      Tsukamoto H, Nagafuji K, Horiuchi T, Mitoma H, Niiro H, Arinobu Y, Inoue Y, To K, Miyamoto T, Iwasaki H, Teshima T, Harada M, Akashi K
    • Journal Title

      Rheumatology (Oxford)

      Volume: 50(5) Pages: 944-952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] Methylenetetrahydrofolate reductase polymorphisms and interaction with smoking and alcohol consumption in lung cancer risk: a case-control study in a Japanese population2011

    • Author(s)
      Kiyohara C, Horiuchi T, Takayama K, Nakanishi Y
    • Journal Title

      BMC Cancer

      Volume: 11 Issue: 1 Pages: 459-459

    • DOI

      10.1186/1471-2407-11-459

    • NAID

      120005133102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390190
  • [Journal Article] Prevalence of and risk factors for low bone mineral density in Japanese female patients with systemic lupus erythematosus2011

    • Author(s)
      Furukawa M, Kiyohara C, Tsukamoto H, Mitoma H, Kimoto Y, Uchino A, Nakagawa M, Oryoji K, Nakashima H, Akashi K, Harada M, Horiuchi T
    • Journal Title

      Rheumatol. Int

      Volume: 31(3) Pages: 365-376

    • NAID

      120004951587

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Journal Article] IL1B rs1143634 polymorphism, cigarette smoking, alcohol use, and lung cancer risk in a Japanese population.2010

    • Author(s)
      Kiyohara C, Horiuchi T, Takayama K, Nakanishi Y.
    • Journal Title

      Journal of Thoracic Oncology 5

      Pages: 299-304

    • NAID

      120005227456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390190
  • [Journal Article] IL1B rs1143634 polymorphism, cigarette smoking, alcohol use, and lung cancer risk in a Japanese population2010

    • Author(s)
      Kiyohara C, Horiuchi T, Takayama K, Nakanishi Y
    • Journal Title

      J Thorac Oncol

      Volume: 5 Issue: 3 Pages: 299-304

    • DOI

      10.1097/jto.0b013e3181c8cae3

    • NAID

      120005227456

    • Data Source
      KAKENHI-PROJECT-21390190
  • [Journal Article] Association of killer cell immunoglobulin-like receptoi 2DL5 with systemic lupus erythematosus and accompanying infections2010

    • Author(s)
      Kimoto Y, Horiuchi T, Tsukamoto H, Kiyohara C, Mitoma H, Uchino A, Furugo I, Yoshizawa S, Ueda A, Harashima S, Sawabe T, Tahira T, Hayashi K, Yoshizawa S, Shimoda T, Akashi K, Harada M.
    • Journal Title

      Rheumatology

      Volume: 49 Pages: 1346-1353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Journal Article] Transmembrane TNF-α. Structure, function and interaction with anti-TNF agents.2010

    • Author(s)
      Horiuchi T, Mitoma H, et al.
    • Journal Title

      Rheumatology (Oxford)

      Volume: 49(7) Pages: 1225-1228

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591172
  • [Journal Article] Cigarette smoking, TP53 Arg72Pro, TP53BP1 Asp353Glu, and the risk of lung cancer in a Japanese population2010

    • Author(s)
      Kiyohara C, Horiuchi T, Miyake Y, Takayama K, Nakanishi Y
    • Journal Title

      Oncol Rep

      Volume: 23 Pages: 1361-1368

    • Data Source
      KAKENHI-PROJECT-21390190
  • [Journal Article] Association study of TRAF1-C5 polymorphisms with susceptibility to rheumatoid arthritis and systemic lupus erythematosus in Japanese.2010

    • Author(s)
      Nishimoto K, Horiuchi T, et al.
    • Journal Title

      Ann.Rheum.Dis.

      Volume: 69(2) Pages: 363-373

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591172
  • [Journal Article] Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.2010

    • Author(s)
      Kimoto Y, Horiuchi T, et al.
    • Journal Title

      Rheumatology (Oxford)

      Volume: 49(7) Pages: 1346-1353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591172
  • [Journal Article] Cigarette smoking, TP53 Arg72Pro, TP53BP1 Asp353Glu, and the risk of lung cancer in a Japanese population.2010

    • Author(s)
      Kiyohara C, Horiuchi T, Miyake Y, Takayama K, Nakanishi Y
    • Journal Title

      Oncology Report

      Volume: 23 Pages: 1361-1368

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390190
  • [Journal Article] Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.2010

    • Author(s)
      Kimoto Y, Horiuchi T, Tsukamoto H, et al.
    • Journal Title

      Rheumatology

      Volume: 49 Pages: 1346-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Journal Article] Tacrolimus is effective for lupus nephritis patients with persistent proteinuria2010

    • Author(s)
      Uchino A, Tsukamoto H, Nakashima H, Yoshizawa S, Furugo I, Mitoma H, Oryoji K, Shimoda T, Niiro H, Tada Y, Yano T, Nonaka T, Oishi R, Akashi K, Horiuchi T.
    • Journal Title

      Clin Exp Rheumatol

      Volume: 28 Pages: 6-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Journal Article] Infectious complications in patients receiving autologous CD34selected hematopoietic stem cell transplantation for severe autoimmune diseases2009

    • Author(s)
      Kohno K, Nagafuji K, Tsukamoto H, Horiuchi T, Takase K, Aoki K, Henzan H, Kamezaki K, Takenaka K, Miyamoto T, Teshima T, Harada M, Akashi K.
    • Journal Title

      Transpl Infect Dis

      Volume: 11 Pages: 318-323

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Journal Article] Combination of TNF-RII, CYP1A1 and GSTM1 polymorphisms and risk of Japanese SLE : findings from the KYSS study2009

    • Author(s)
      Horiuchi T, Washio M, Kiyohara C, Tsukmaoto H, et al.
    • Journal Title

      Rheumatology 48

      Pages: 1045-1049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Journal Article] Combination of TNF-RII, CYP1A1and GSTM1 polymorphisms and the risk of Japanese SLE : findings from the KYSS study2009

    • Author(s)
      Horiuchi T, et al.
    • Journal Title

      Rheumatology(Oxford) 48

      Pages: 1045-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591172
  • [Journal Article] Kyushu Sapporo SLE Study Group. Combination of TNF-RII, CYP1A1 and GSTM1 polymorphisms and the risk of Japanese SLE : findings from the KYSS study2009

    • Author(s)
      Horiuchi T, Washio M, Kiyohara C, Tsukamoto H, Tada Y, Asami T, Ide S, Kobashi G, Takahashi H
    • Journal Title

      Rheumatology

      Volume: 48 Pages: 1045-1049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Journal Article] Association of polymorphisms in complement component C3 gene with susceptibility to systemiclupus erythematosus.2008

    • Author(s)
      Miyagawa H, Horiuchi T, et al.
    • Journal Title

      Rheumatology (Oxford) 47

      Pages: 158-164

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591172
  • [Journal Article] Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus.2008

    • Author(s)
      Miyagawa H, Yamai M, Sakaguchi D, Kiyohara C, Tsukamoto H, Kimoto Y, Nakamura T, Lee J-H, Tsai C-Y, Chiang B-L, Nagasawa K, Harada M, Tahira T, Hayashi K, Horiuchi T.
    • Journal Title

      Rheumatology 47(2)

      Pages: 158-164

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019051
  • [Journal Article] Mechanism for cytotoxic effects of anti-TNF-a agents on transmembrane TNF-expressing cells:comparison among infliximab,etanercept and adalibmab2008

    • Author(s)
      Mitoma H, Horiuchi T, Tsukamoto H, et. al.
    • Journal Title

      Arthritis Rheum (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] Mechanisms for cytotoxic effects of anti-tumor necrosis factor agents on transmembrane tumor necrosis factor alpha-expressing cells: Comparison among infliximab,etanercept,and adalimumab2008

    • Author(s)
      Mitoma H, Horiuchi T, Tsukamoto H, et. al.
    • Journal Title

      Arthritis Rheum 58

      Pages: 1248-57

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus2008

    • Author(s)
      Miyagawa, H, Yamai, M, Kiyohara, C, Tsukamoto, H, Kimoto, Y, Nakamura, T, Lee, J-H., Tsai, C-Y., Tsai, C-Y, Chiang, B-L, Shimoda, T, Harada, M, Tahira, T, Hayashi, K, Horiuchi, T
    • Journal Title

      Rheumatology 47

      Pages: 158-64

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] A dose-escalation study of rituximab for treatment of systemic lupus erythematosus and Evans' syndrome : Immunological analysis of B cells, T cells and cytokines.2008

    • Author(s)
      Tamimoto Y, Horiuchi T, et al.
    • Journal Title

      Rheumatology (Oxford) 47

      Pages: 821-827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591172
  • [Journal Article] Mechanisms for cytotoxic effects of anti-TNF agents on transmembrane TNF-expressing cells : comparison among infliximab, etanercept and adalimumab.2008

    • Author(s)
      Mitoma H, Horiuchi T, et al.
    • Journal Title

      Arthritis Rheum 58(5)

      Pages: 1248-1257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591172
  • [Journal Article] Mechanism for cytotoxic effects of anti-TNF-α agents on transmembrane TNF-expressing cells : comparison among infliximab, etanercept and adalibmab2008

    • Author(s)
      Mitoma, H, Horiuchi, T, Tsukamoto, H, Tamimoto, Y, Kimoto, Y, Uchino, A, To, K, Harashima, S, Hatta, N, Harada, M
    • Journal Title

      Arthritis Rheum 58

      Pages: 1248-57

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] A dose-escalation study of rituximab for treatment of systemic lupus erythematosus and Evans' syndrome : Immunological analysis of B cells, T cells and cytokines2008

    • Author(s)
      Tamimoto, Y, Horiuchi, T, Tsukamoto, H, Kiyohara, C, Niro, H, Miyagawa, H, Nakasone, A, Mitoma, H, Kimoto, Y, Uchino, A, Muta, K, Abe, Y, Inoue, Y, Ueda, A, Nakashima, H, Tada, Y, Nagasawa, K, Yoshizawa, S, Shimoda, T, Harada, M
    • Journal Title

      Rheumatology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] A functional M196R polymorphism of TNF receptor type 2 is associated with SLE : a case control study and a meta-analysis2007

    • Author(s)
      Horiuchi T, Kiyohara C, Tsukamoto H et al.
    • Journal Title

      Ann Rheum Dis 66(3)

      Pages: 320-324

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] A functional M196R polymorphism of tumor necrosis factor receptor type 2 is associated with systemic lupus erythematosus : a case-control study and a meta-analysis.2007

    • Author(s)
      Horiuchi T, Kiyohara C, Tsukamoto H, Okamura S, Nagasawa K, Harada M., et al.
    • Journal Title

      Ann.Rheum.Dis. 66(3)

      Pages: 320-324

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019051
  • [Journal Article] A functional M196R polymorphism of tumor necrosis factor receptor type 2 is associated with systemic lupus erythematosus : A case-control study and a meta-analysis.2007

    • Author(s)
      Horiuchi T, Kiyohara C, Tsukamoto H, et al.
    • Journal Title

      Ann Rheum Dis 66

      Pages: 320-324

    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] A functional M196R polymorphism of tumor necrosis factor receptor type 2 is associated with systemic lupus erythematosus : A case-control study and a meta-analysis2007

    • Author(s)
      Horiuchi, T, Kiyohara, C, Tsukamoto, H, Sawabe, T, Furugo, I, Yoshizawa, S, Ueda, A, Nakamura, Y, Tada, Y, Kimoto, Y, Mitoma, H, Harashima, SI, Yoshizawa, S, Shimoda, T, Okamura, S, Nagasawa, K, Harada, M
    • Journal Title

      Ann Rheum Dis 66

      Pages: 320-324

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] A functional M196R polymorphism of tumor necrosis factor receptortype 2 is associated with systemic lupus erythematosus:A case-control study and a meta-analysis2007

    • Author(s)
      Horiuchi T, Kiyohara C, Tsukamoto H, et. al.
    • Journal Title

      Ann Rheum Dis 66

      Pages: 320-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] A functional M196R polymorphism of tumor necrosis factor receptor type 2 is associated with systemic lupus erythematosus : a case-control study and a meta-analysis.2007

    • Author(s)
      Horiuchi T, et al.
    • Journal Title

      Ann. Rheum. Dis. 66

      Pages: 320-324

    • Data Source
      KAKENHI-PROJECT-17019051
  • [Journal Article] A functional M196R polymorphism of tumor necrosis factor receptor type 2 is associated with systemic lupus erythematosus: A case-control study and a meta-analysis2007

    • Author(s)
      Horiuchi T, Kiyohara C, Tsukamoto H, et. al.
    • Journal Title

      Ann Rheum Dis 66

      Pages: 320-4

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] A functional M196R polymorphism of TNF receptor type 2 is associated with SLE : a case control study and a meta-analysis2007

    • Author(s)
      Horiuchi T, Kiyohara C, et al.
    • Journal Title

      Ann Rheum Dis 66(3)

      Pages: 320-324

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] Increased expression of membrane TNF-alpha on activated peripheral CD8+ T cells in systemic lupus erythematosus.2006

    • Author(s)
      Horiuchi T, Morita C, Tsukamoto H et al.
    • Journal Title

      Int J Mol Med 17

      Pages: 875-879

    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] Prevention of steroid-induced osteonecrosis of femoral head in systemic lupus erythematosus by anti-coagulant2006

    • Author(s)
      Nagasawa K, Tada Y, Horiuchi T et al.
    • Journal Title

      Lupus 15

      Pages: 354-357

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] Smoking, drinking, sleeping habits and other lifestyle factors and the risk of systemic lupus erythematosus (SLE) in Japanese females : findings from the KYSS study2006

    • Author(s)
      Washio M, Horiuchi T, et al.
    • Journal Title

      Mod Rheumatol 16

      Pages: 143-150

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] A Phase I-II Trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease2006

    • Author(s)
      Tsukamoto H, Nagafuji K, Horiuchi T, et al.
    • Journal Title

      Ann Rheum Dis 65(4)

      Pages: 508-514

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] Prevention of steroid-induced osteonecrosis of femoral head in systemic lupus erythematosus by anti-coagulant2006

    • Author(s)
      Nagasawa K, Tada Y, Horiuchi T, et al.
    • Journal Title

      Lupus 15

      Pages: 354-357

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] Prevention of steroid-induced osteonecrosis of femoral head in systemic lupus erythematosus by anti-coagulant2006

    • Author(s)
      Nagasawa K, Tada Y, Horiuchi T
    • Journal Title

      Lupus 15

      Pages: 354-357

    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] A Phase I-II trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease.2006

    • Author(s)
      Tsukamoto H, Nagafuji K, Horiuchi T, Miyamoto T, Aoki K, Takase K, Henzan H, Himeji D, Koyama T, Miyake K, Inoue Y, Nakashima H, Otsuka T, Tanaka Y, Nagasawa K, Harada M
    • Journal Title

      Ann Rheum Dis 65

      Pages: 508-514

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Increased expression of membrane TNF-alpha on activated peripheral CD8+ T cells in systemic lupus erythematosus2006

    • Author(s)
      Horiuchi, T, Morita, C, Tsukamoto, H, Mitoma, H, Sawabe, T, Harashima, S, Kashiwagi, Y, Okamura, S
    • Journal Title

      Int J Mol Med 17

      Pages: 875-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] A Phase I-II trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease2006

    • Author(s)
      Tsukamoto, H, Nagafuji, K, Horiuchi, T, Miyamoto, T, Aoki, K, Takase, K, Henzan, H, Himeji, D, Koyama, T, Miyake, K, Inoue, Y, Nakashima, H, Otsuka, T, Tanaka, Y, Nagasawa, K, Harada, M
    • Journal Title

      Ann Rheum Dis 65

      Pages: 508-14

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] Increased expression of membrane TNF-□ on activated peripheral CD8+ T cells in systemic lupus erythematosus2006

    • Author(s)
      Horiuchi T, et al.
    • Journal Title

      Int J Mol Med 17 (5)

      Pages: 875-879

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] A phaseI-II trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease2006

    • Author(s)
      Tsukamoto H, Nagafuji K, Horiuchi T, et. al.
    • Journal Title

      Ann Rheum Dis 65

      Pages: 508-14

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] Increased expression of membrane TNF-α on activated peripheral CD8+ T cells in systemic lupus erythematosus2006

    • Author(s)
      Horiuchi T, et al.
    • Journal Title

      Int J Mol Med 17(5)

      Pages: 875-879

    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] Smoking, drinking, sleeping habits and other lifestyle factors and the risk of systemic lupus erythematosus (SLE) in Japanese females : findings from the KYSS study2006

    • Author(s)
      Washio M, Horiuchi T, Kiyohara C et al.
    • Journal Title

      Mod Rheumatol 16

      Pages: 143-150

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] Increased expression of membrane TNF-alpha on activated peripheral CD8+ T cells in systemic lupus erythematosus2006

    • Author(s)
      Horiuchi T, Morita C, Tsukamoto H et al.
    • Journal Title

      Int J Mol Med 17(5)

      Pages: 875-879

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] Smoking, drinking, sleeping habits, and other lifestyle factors and the risk of systemic lupus erythematosus in Japanese females : findings from the KYSS study.2006

    • Author(s)
      Washio M, Horiuchi T, Kiyohara C, et al.
    • Journal Title

      Mod Rheumatol 16

      Pages: 143-150

    • NAID

      10017608637

    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] A phase I-II trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease.2006

    • Author(s)
      Tsukamoto H, Nagafuji K, Horiuchi T, et al.
    • Journal Title

      Ann Rheum Dis 65

      Pages: 508-514

    • Data Source
      KAKENHI-PROJECT-18591113
  • [Journal Article] A Phase I-II Trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease2006

    • Author(s)
      Tsukamoto H, Nagafuji K, Horiuchi T, et al.
    • Journal Title

      Ann Rheum Dis 65 (4)

      Pages: 508-514

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] A Phase I-II trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease2006

    • Author(s)
      Tsukamoto H, Nagafuji K, Horiuchi T et al.
    • Journal Title

      Ann Rheum Dis 65

      Pages: 508-514

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus.2005

    • Author(s)
      Mitoma H, Horiuchi T, Kimoto Y, Tsukamoto H, Uchino A, Tamimoto Y, Miyagi Y, Harada M
    • Journal Title

      Int J Mol Med 16

      Pages: 609-615

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha.2005

    • Author(s)
      Mitoma H, Horiuchi T, Hatta N, Tsukamoto H, Harashima S, Kikuchi Y, Otsuka J, Okamura S, Fujita S, Harada M
    • Journal Title

      Gastroenterology 128

      Pages: 376-392

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus2005

    • Author(s)
      Mitoma H, Horiuchi T, Kimoto Y, Tsukamoto H et al.
    • Journal Title

      Int J Mol Med 16

      Pages: 609-615

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Molecular analysis of a novel hereditary C3 deficienc with systemic lupus erythematosus2005

    • Author(s)
      Tsukamoto H, Horiuchi T et al.
    • Journal Title

      Biochem Biophys Res Commun 330

      Pages: 298-304

    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] Association of MBL gene polymorphisms with major bacterial infection in patients treated with high-dose chemotherapy and autologous PBSCT.2005

    • Author(s)
      Horiuchi T, Gondo H, Miyagawa H, Otsuka J, Inaba S, Nagafuji K, Takase K, Tsukamoto H, Koyama T, Mitoma H, Tamimoto Y, Miyagi Y, Tahira T, Hayashi K, Hashimura C, Okamura S, Harada M
    • Journal Title

      Genes Immun 6

      Pages: 162-166

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus eryhtematosus2005

    • Author(s)
      Mitoma H Horiuchi T et al.
    • Journal Title

      Int J Mol Med 16

      Pages: 609-614

    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] Association of MBL gene polymorphisms with major bacterial infection in patients treated with high-dose chemotherapy and autologous PBSCT2005

    • Author(s)
      Horiuchi T, Gondo H, Miyagawa H, et al.
    • Journal Title

      Genes Immun 6

      Pages: 162-166

    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Molecular analysis of a novel hereditary C3 deficiency with systemic lupus erythematosus.2005

    • Author(s)
      Tsukamoto H, Horiuchi T, Kokubo H et al.
    • Journal Title

      Biochem Biophys Res Commun 330

      Pages: 298-304

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Association of MBL gene polymorphisms with major bacterial infection in patients treated with high-dose chemotherapy and autologous PBSCT2005

    • Author(s)
      Horiuchi T, et al.
    • Journal Title

      Genes Immun 6

      Pages: 162-166

    • Data Source
      KAKENHI-PROJECT-17019051
  • [Journal Article] Decreased expression of interleukin-21 receptor on peripheral B lymphocytes in systemic lupus erythematosus2005

    • Author(s)
      Mitoma H, Horiuchi T, Kimoto Y, Tsukamoto H, et al.
    • Journal Title

      Int J Mol Med 16

      Pages: 609-615

    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Molecular Analysis of A Novel Hereditary C3 Deficiency with Systemic Lupus Erythematosus.2005

    • Author(s)
      Tsukamoto H, Horiuchi T, Kokuba H, Nagae S, Nishizaka H, Sawabe T, Harashima S, Himeji D, Koyama T, Otsuka J, Mitoma H, Kimoto Y, Hashimura C, Kitano E, Kitamura H, Furue H, Harada M
    • Journal Title

      Biochem.Biophys.Res.Commun 330

      Pages: 298-304

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha2005

    • Author(s)
      Mitoma H, Horiuchi T, Hatta N, Tsukamoto H, et al.
    • Journal Title

      Gastroenterology 128

      Pages: 376-392

    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF2005

    • Author(s)
      Mitoma H Horiuchi T, et al.
    • Journal Title

      Gastroenterology 128

      Pages: 376-392

    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha2005

    • Author(s)
      Mitoma H, Horiuchi T, Hatta N, Tsukamoto H et al.
    • Journal Title

      Gastroenterology 128

      Pages: 376-92

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Molecular analysis of a novel hereditary C3 deficiency with systemic lupus erythematosus.2005

    • Author(s)
      Tsukamoto H, Horiuchi T, Kokuba H et al.
    • Journal Title

      Biochem Biophys Res Commun 330

      Pages: 298-304

    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Association of MBL gene polymorphisms with major bacterial infection in patients treated with high-dose chemotherapy and autologous PBSCT2005

    • Author(s)
      Horiuchi T, Gondo H, et al.
    • Journal Title

      Genes Immun 6

      Pages: 162-166

    • Data Source
      KAKENHI-PROJECT-17591048
  • [Journal Article] Association of MBL gene polymorphisms with major bacterial infection in patients treated with high-dose chemotherapy and autologous PBSCT.2005

    • Author(s)
      Horiuchi T, Gondo H, Miyagawa H, Otsuka J, Inaba S, Nagafuji K, Takase K, Tsukamoto H, Koyama T, Mitoma H, Tamimoto Y, Miyagi Y, Tahira T, Hayashi K, Hashimura C, Okamura S, Harada M.
    • Journal Title

      Gene Immun 6(2)

      Pages: 162-166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019051
  • [Journal Article] Association of MBL gene polymorphisms with major bacterial infection in patients treated with high-dose chemotherapy and autologous PBSCT2005

    • Author(s)
      Horiuchi T, Gondo H, Miyagawa H et al.
    • Journal Title

      Genes Immun 6

      Pages: 162-166

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Association of a four-amino acid residue insertion polymorphism of the HS1 gene with systemic lupus erythematosus : molecular and functional analysis.2004

    • Author(s)
      Otsuka J, Horiuchi T, Yoshizawa S, Tsukamoto H, Sawabe T, Kikuchi Y, Himeji D, Koyama T, Mitoma H, Watanabe T, Harada M
    • Journal Title

      Arthritis Rheum 50

      Pages: 871-881

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Binding activities of infliximab and etanercept to transmembrane tumor necrosis factor-alpha2004

    • Author(s)
      Mitoma H, Horiuchi T, Tsukamoto H et al.
    • Journal Title

      Gastroenterology 126

      Pages: 934-935

    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Novel mutations in TNFRSF1A in patients with typical tumor necrosis factor receptor-associated periodic syndrome and with SLE2004

    • Author(s)
      Horiuchi T, Tsukamoto H, et al.
    • Journal Title

      Int.J.Mol.Med. 14

      Pages: 813-818

    • Data Source
      KAKENHI-PROJECT-16012247
  • [Journal Article] Novel mutations in TNFRSF1A in patients with typical tumor necrosis factor receptor-associated periodic syndrome and with systemic lupus erythematosus in Japanese.2004

    • Author(s)
      Horiuchi T, Tsukamoto H, Mitoma H, Miyagawa H, Tamimoto Y, Yoshizawa S, Harada M, Hayashi K, Hashimura C, Oribe M, Okamura S
    • Journal Title

      Int J Mol Med 14

      Pages: 813-818

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Novel mutations in TNFRSF1A in patients with typical tumor necrosis factor receptor-associated periodic syndrome and with systemic lupus erythematosus in Japanese2004

    • Author(s)
      Horiuchi T, Tsukamoto H, Mitoma H et al.
    • Journal Title

      Int J Mol Med 14

      Pages: 813-818

    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] OPGand RANKL expression in the fibroblast-like synoviocytes from RA and OA patients2004

    • Author(s)
      Harashima S, Horiuchi T, et al.
    • Journal Title

      Rheumatology(Oxford) 43

      Pages: 396-397

    • Data Source
      KAKENHI-PROJECT-16012247
  • [Journal Article] Binding activities of infliximab and etanercept to transmembrane TNF-α2004

    • Author(s)
      Mitoma H, Horiuchi T, et al.
    • Journal Title

      Gastroenterology 126

      Pages: 934-935

    • Data Source
      KAKENHI-PROJECT-16012247
  • [Journal Article] Association of a four-amino-acid-residue-insertion polymorphism of the HS1 gene with systemic lupus erythematosus2004

    • Author(s)
      Otsuka J, Horiuchi T, et al.
    • Journal Title

      Arthritis Rheum. 50

      Pages: 871-881

    • Data Source
      KAKENHI-PROJECT-16012247
  • [Journal Article] Association of a four-amino acid residue insertion polymorphism of the HS1 gene with systemic lupus erythematosus : molecular and functional analysis2004

    • Author(s)
      Otsuka J, Horiuchi T, Yoshizawa S, Tsukamoto H et al.
    • Journal Title

      Arthritis Rheum 50

      Pages: 871-881

    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Molecular analysis of a novel hereditary C3 deficiency with systemic lupus erythematosus.

    • Author(s)
      Tsukamoto H, Horiuchi T, Kokuba H et al.
    • Journal Title

      Biochem Biophys Res Commun (in press)

    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Genetic polymorphisms involved in carcinogen metabolism and DNA repair and lung cancer risk in a Japanese population

    • Author(s)
      Kiyohara C, Horiuchi T, Takayama K, Nakanishi Y
    • Journal Title

      J Thorac Oncol

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390190
  • [Journal Article] A Phase I-II trial of autologous peripheral blood stem cell transplantation in the treatment of refractory autoimmune disease

    • Author(s)
      Tsukamoto H, Nagafuji K, Horiuchi T, et al.
    • Journal Title

      Ann Rheum Dis (印刷中)

    • Data Source
      KAKENHI-PROJECT-16590984
  • [Journal Article] Analysis of immune reconstitution after autologous CD34+ stem/progenitor cell transplantation for systemic sclerosis : predominant reconstitution of Th1 CD4+ T cells.

    • Author(s)
      Tsukamoto H, Nagafuji K, Horiuchi T, et al
    • Journal Title

      Rheumatology

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Presentation] リウマチ膠原病患者におけるCOVID-19の動向:JCR COVID-19レジストリ2023

    • Author(s)
      柏戸佑介、木本泰孝、奥健志、堀内孝彦
    • Organizer
      第67回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-22K07447
  • [Presentation] リウマチ医が知っておきたい補体学2023

    • Author(s)
      堀内孝彦
    • Organizer
      第67回日本リウマチ学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Presentation] 新時代を迎えた補体学~知っておきたい臨床への展開2020

    • Author(s)
      堀内孝彦、井上徳光、若宮伸隆
    • Organizer
      第64回日本リウマチ学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Presentation] 内科医が知っておきたい補体関連疾患2020

    • Author(s)
      堀内孝彦
    • Organizer
      第117回日本内科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Presentation] Telomere shortening is accelerated in a gender-differential manner in patients with insomnia receiving sleep medication.2019

    • Author(s)
      Tomotake Tokunou, Toyoki Maeda, Takahiko Horiuchi, Naoki Makino
    • Organizer
      5th Asean Sleep Federation Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08041
  • [Presentation] Accumulation of Gold Nano-rods in the Failing Heart of Transgenic Mice with the Cardiac-specific Expression of TNF-α2019

    • Author(s)
      樋口義洋、得能智武、久保田徹、堀内孝彦
    • Organizer
      第83回日本循環器学会
    • Data Source
      KAKENHI-PROJECT-18K08041
  • [Presentation] A Missense Mutation Of The Plasminogen Gene In Hereditary Angioedema With Normal C1 Inhibitor In Japan2019

    • Author(s)
      Horiuchi T, Yakushiji H, Fukuoka K, Miyahara H, Hashimura C
    • Organizer
      European Academy of Allergy and Clinical Immunology June 01-05, 2019 Lisboa, Portugal
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03564
  • [Presentation] 遺伝性血管性浮腫の最近の話題2018

    • Author(s)
      堀内孝彦
    • Organizer
      第1回日本免疫不全・自己炎症学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09246
  • [Presentation] 遺伝性血管性浮腫(HAE)における最近の進歩2018

    • Author(s)
      堀内孝彦
    • Organizer
      第67回日本アレルギー学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09246
  • [Presentation] Japanese internet-based patient registration system for hereditary angioedema: results of clinical characteristics2016

    • Author(s)
      Horiuchi T, Harashima S-I, Kiyohara C, Nomura K, Hashimura C
    • Organizer
      26th International Complement Workshop
    • Place of Presentation
      Kanazawa
    • Year and Date
      2016-09-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09246
  • [Presentation] 難治性自己免疫疾患に対する 造血幹細胞移植療法 ーその基礎と臨床ー2013

    • Author(s)
      塚本 浩、堀内孝彦
    • Organizer
      第41回日本臨床免疫学会
    • Place of Presentation
      下関
    • Data Source
      KAKENHI-PROJECT-24591465
  • [Presentation] 難治性自己免疫疾患に対する造血幹細胞移植療法-その基礎と臨床-2013

    • Author(s)
      塚本浩、堀内孝彦
    • Organizer
      第41回日本臨床免疫学会総会
    • Place of Presentation
      下関
    • Year and Date
      2013-11-29
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Presentation] 全身性硬化症に対するCD34陽性細胞純化及び非純化自己造血幹細胞移植 :4年間の比較2013

    • Author(s)
      塚本 浩、堀内孝彦、綾野雅宏、新納宏昭、有信洋二郎1、赤星光輝、上田尚靖、田中 淳、大田俊一郎、植木尚子、久本仁美、上田 彰、廣崎友里、押領司大助、赤司浩一
    • Organizer
      第58回日本リウマチ学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24591465
  • [Presentation] Seven-year follow-up of autologous hematopoietic stem cell transplantation for severe systemic sclerosis2013

    • Author(s)
      Tsukamoto H, Horiuchi H, Miyamoto T, Niiro H, Arinobu Y, Akahosh Mi, Masahiro Ayano, Atsushi Tanaka, Naoyasu Ueda, Koichi Akashi
    • Organizer
      Annual European Congress of Rheumatology 2013
    • Place of Presentation
      Madrid, Spain
    • Data Source
      KAKENHI-PROJECT-24591465
  • [Presentation] 我が国におけるTRAPS(TNF受容体関連周期性症候群)の特徴2013

    • Author(s)
      堀内孝彦
    • Organizer
      第116回日本小児科学会学術集会
    • Place of Presentation
      広島
    • Year and Date
      2013-04-20
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Presentation] 全身性硬化症に対する自己造血幹細胞移植の長期成績2012

    • Author(s)
      塚本 浩、堀内孝彦、綾野雅宏、新納宏昭、有信洋二郎1、井上 靖、上田尚靖、田中 淳、大田俊一郎、植木尚子、久本仁美、上田 彰、古川牧緒、原田実根2、赤司浩一
    • Organizer
      第57回日本リウマチ学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24591465
  • [Presentation] Long-term follow-up of autologous hematopoietic stem cell transplantation for severe systemic sclerosis2012

    • Author(s)
      Hiroshi Tsukamoto, Takahiko Horiuchi, Toshihiro Miyamoto, Hiroaki Niiro, Yojiro Arinobu, Yasushi Inoue, Masahiro Ayano, Atsushi Tanaka, Naoyasu Ueda, Mine Harada1, Koichi Akashi
    • Organizer
      Annual European Congress of Rheumatology 2012
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-24591465
  • [Presentation] 全身性エリテマトーデス―病態解明と治療の最近の進歩―2012

    • Author(s)
      堀内孝彦
    • Organizer
      第27回日本臨床リウマチ学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2012-11-24
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Presentation] Influence of genetic polymorphisms of TP53 Arg72Pro and TP53BP1 Asp353Glu and smoking on lung cancer risk2011

    • Author(s)
      Kiyohara C, Horiuchi T, Nakanishi Y
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21390190
  • [Presentation] 全身性硬化症に対するCD34陽性細胞純化及び非純化自己造血幹細胞移植2011

    • Author(s)
      塚本浩、堀内孝彦、新納宏昭、他
    • Organizer
      第55回日本リウマチ学会総会
    • Place of Presentation
      神戸市
    • Year and Date
      2011-07-20
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Presentation] 難治性炎症性疾患の画期的治療薬-抗TNF製剤の基礎と臨床-2011

    • Author(s)
      堀内孝彦
    • Organizer
      第40回日本免疫学会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2011-11-29
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Presentation] CD34-selected and unmanipulated autologous hematopoietic stem cell transplantation for severe systemic sclerosis2011

    • Author(s)
      Tsukamoto H, Horiuchi T, Miyamoto T, et al
    • Organizer
      Annual European Congress of Rheumatology
    • Place of Presentation
      London, UK
    • Year and Date
      2011-05-27
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Presentation] 抗TNF製剤の作用機序:その共通点と相違点2010

    • Author(s)
      堀内孝彦
    • Organizer
      第54回日本リウマチ学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-20591172
  • [Presentation] 全身性硬化症に対する大量免疫抑制療法と自己造血幹細胞移植2010

    • Author(s)
      塚本浩、堀内孝彦、三苫弘喜、他
    • Organizer
      第54回日本リウマチ学会総会
    • Place of Presentation
      神戸市
    • Year and Date
      2010-04-24
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Presentation] Autologous hematopoietic stem cell transplantation for severe systemic sclerosis2010

    • Author(s)
      Tsukamoto H, Horiuchi T, Miyamoto T, et al
    • Organizer
      long-term follow-up analysis of immune reconstitution. Annual European Congress of Rheumatology
    • Place of Presentation
      Rome. Italy
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Presentation] 全身性硬化症に対する大量免疫抑制療法と自己末梢血純化CD34陽性細胞移植:術後5年間の臨床成績と免疫学的検討2009

    • Author(s)
      塚本浩、堀内孝彦、三苫弘喜、他
    • Organizer
      第53回日本リウマチ学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-24
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Presentation] ループス腎炎に対する宅ロリムすの有効性と安全性-投与開始後1年経過した29例の解析-2009

    • Author(s)
      堀内孝彦
    • Organizer
      日本リウマチ学会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-24
    • Data Source
      KAKENHI-PROJECT-20591172
  • [Presentation] 全身性硬化症に対する大量免疫抑制療法と非純化自己末梢血細胞移植の短期成績2009

    • Author(s)
      塚本浩、堀内孝彦、三苫弘喜、他
    • Organizer
      第53回日本リウマチ学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-24
    • Data Source
      KAKENHI-PROJECT-21591266
  • [Presentation] ループス腎炎の維持療法としてのタクロリムスの有効性と安全既2008

    • Author(s)
      堀内孝彦
    • Organizer
      第23回日本臨床リウマチ学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-11-29
    • Data Source
      KAKENHI-PROJECT-20591172
  • [Presentation] 滑膜線維芽細胞におけるAPRIL発現2007

    • Author(s)
      高橋 美聡、塚本 浩、堀内 孝彦, 他
    • Organizer
      第51回日本リウマチ学会総会
    • Place of Presentation
      東京
    • Year and Date
      2007-04-26
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Presentation] 滑膜線維芽細胞におけるAPRIL発現2007

    • Author(s)
      高橋 美聡, 塚本 浩, 堀内 孝彦, 他
    • Organizer
      第51回日本リウマチ学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-04-26
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Presentation] High-dose immune suppressive therapy and autologous peripheral blood stem cell transplantation in systemic sclerosis : analysis of immune reconstitution2006

    • Author(s)
      Tsukamoto, H, Nagafuji, K, Horiuchi, T, Nakashima, H, Harada, M
    • Organizer
      Annual meeting of American college of rheumatology
    • Place of Presentation
      Washington, DC
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Presentation] 全身性エリテマトーデス ―病態解明と治療の最近の進歩―

    • Author(s)
      堀内孝彦
    • Organizer
      第27回日本臨床リウマチ学会総会
    • Place of Presentation
      神戸
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Presentation] TNF阻害薬の登場から10年たって -その現状と未来-

    • Author(s)
      堀内孝彦
    • Organizer
      第32回日本炎症・再生医学会(招待講演)
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Presentation] 難治性自己免疫疾患に対する造血幹細胞移植療法 -その基礎と臨床-

    • Author(s)
      塚本浩、堀内孝彦
    • Organizer
      第41回日本臨床免疫学会シンポジウム
    • Place of Presentation
      下関
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Presentation] Role of BAFF and APRIL in differentiation to plasmablast from human peripheral B cells

    • Author(s)
      Uchino, A, Tsukamoto, H, Horiuchi, T, Mitoma, H, Taminoto, Y, Kimoto, Y, Oryoji, K, Furukawa, M, To, K, Harada, M
    • Organizer
      The 51th Annual meeting of Japan college of rheumatology
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Presentation] 難治性炎症性疾患の画期的治療薬-抗TNF製剤の基礎と臨床-

    • Author(s)
      堀内孝彦
    • Organizer
      第40回日本免疫学会学術集会(招待講演)
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Presentation] 感染を繰り返した先天性補体C3欠損症の遺伝子解析

    • Author(s)
      塚本 浩、藤健太郎、三苫弘喜、新納宏昭、有信洋二郎、赤星光輝、赤司浩一、北野悦子、畑中道代、北村 肇、堀内孝彦
    • Organizer
      第51回補体シンポジウム
    • Place of Presentation
      神戸
    • Year and Date
      2014-08-21 – 2014-08-22
    • Data Source
      KAKENHI-PROJECT-24591465
  • [Presentation] 全身性エリテマトーデスの病態解明と治療-最近の進歩-

    • Author(s)
      堀内孝彦
    • Organizer
      第55回日本リウマチ学会総会
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Presentation] 我が国におけるTRAPS(TNF受容体関連周期性症候群)の特徴

    • Author(s)
      堀内孝彦
    • Organizer
      第116回小児科学会シンポジウム
    • Place of Presentation
      広島
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Presentation] High-dose cyclophosphamide and autologous peripheral blood stem cell transplantation for severe scleroderma clinical results and analysis of immune reconstitution

    • Author(s)
      Tsukamoto, H, Nagafuji, K, Horiuchi, T, Harada, M
    • Organizer
      International workshop on scleroderma
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591113
  • [Presentation] TNF阻害薬の作用機序 ―共通点と相違点、そして臨床効果との関連―

    • Author(s)
      堀内孝彦
    • Organizer
      第22回日本脊椎関節炎学会総会
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591464
  • [Presentation] Expression of APRIL in svnovial fibroblast-like cells

    • Author(s)
      Takahashi, M, Tsukamoto, H, Horiuchi, T, Mitoma, H, Uchino, A, Kimoto, Y, Oryoji, K, Furukawa, M, To, K, Harada, M
    • Organizer
      The 51th Annual meeting of Japan college of rheumatology
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591113
  • 1.  TSUKAMOTO Hiroshi (70304772)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 88 results
  • 2.  HAYASHI Kenshi (00019671)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 2 results
  • 3.  TAHIRA Tomoko (50155230)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 5 results
  • 4.  KIYOHARA Chikako (00169963)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 5.  NAKANISHI Yoichi (20172356)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 6.  TAKAYAMA Koichi (50274444)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 7.  YOSHIZAWA Shigeru (20191562)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  TOKUNOU Tomotake (50567378)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 9.  木本 泰孝 (40735487)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 10.  樋口 義洋 (40404032)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 11.  KUKITA Yoji (60372744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  HIGASA Koichiro (10419583)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  YASUKAWA Masaki (60127917)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NAGASAWA Kohei (00108721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  USHIYAMA Osamu (40253596)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  Maeda Toyoki (30264112)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 17.  三宅 吉博 (50330246)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  井田 弘明 (60363496)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  田中 良哉 (30248562)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  山村 昌弘 (80252956)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  田村 直人 (20227284)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  熊谷 俊一 (00153346)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  真弓 武仁 (70219541)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  小柳 雅孔 (00325474)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  宮原 寿明 (10209934)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 26.  宮田 敏行 (90183970)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  新留 琢郎 (20264210)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  柏戸 佑介 (80761014)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 29.  INATSUKI Akira
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  IKEDA Kei
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  NISHIZAKA Hiroaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  上田 良輝
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  都留 智巳
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  ARINOBU Yojiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 35.  NIIRO Hiroaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 36.  奥 健志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  綾野 雅宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 38.  西村 啓佑
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  西小森 隆太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  赤司 浩一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 41.  山崎 聡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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