Miyajima Hiroaki 宮嶋裕明

… Alternative Names

MIYAJIMA Hiroaki 宮嶋裕明

MITAJIMA Hiroaki 宮嶋裕明

宮崎裕明ミヤザキヒロアキ

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Researcher Number	90221613
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2014 – 2016: 浜松医科大学, 医学部, 教授 2010 – 2012: 浜松医科大学, 医学部, 教授 2010: 浜松医科大学, 医学部, 准教授 1999 – 2005: HAMAMATSU UNIV. SCH. OF MED., FIRST DEPARTMENT OF MEDICINE, ASSOCIATE PROFESSOR, 医学部, 助教授 1997 – 1998: HAMAMATSU UNIV.SCH.OF MED., FIRST DEPARTMENI OF MEDICINE,ASSISTANT PROFESSOR, 医学部附属病院, 講師 1996 – 1997: 浜松医科大学, 医学部・附属病院, 講師 1994 – 1995: 浜松医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Neurology / Neurology Except Principal Investigator Neurology / Radiation science
Keywords	Principal Investigator セルロプラスミン / 鉄 / 脂質過酸化 / FREE RADICAL / IRON / LIPID PEROXIDATION / CERULOPLASMIN / フリーラジカル / 遺伝子異常 / 無セルロプラスミン血症 … More / 遺伝子発現 / 鉄代謝 / フェロオキシダーゼ / 小胞体 / 小胞体ストレス / 銅 / フェロオキシダーゼ活性 / 極長鎖脂肪酸 / 封入体 / アストロサイト / ヘプシジン / ミトコンドリア / トランスフェリン / フェロポルチン / 神経変性症 / Ferroxidase / Neuronal cell death / Gene expression / Endplasmic reticulum / Loss-of-function / Gene mutation / Iron metabolism / Ceruloplasmin / 蛋白分解 / ミスセンス変換 / ヘテロ接合体 / 神経細胞死 / loss-of-function / 遺伝子変異 / SECRETORY PATHWAY / FERROXIDASE / MITOCHONDRIA / MISSENSE MUTATION / タエロオキシダーゼ / エネルギー産生系 / 銅抱合能 / 蛋白発現 / ミスセンス変異 / TRUNCATION / MUTATION / CEREBROSPINAL FLUID / GENE FREQUENCY / 遺伝子頻度 / スーパーオキシドジスムターゼ / 髄液 / IRON CHELATOR / GENE MUTATION / PEROXISOME / VERY LONG-CHAIN FATTY ACID / セルロプラスミン欠損症 / プルオキシゾーム / 鉄キレート剤 / lipid peroxidation / thiobarbituric acid-reactive substance / gene mutation / iron / ceruloplasmin / チオバルビツール酸反応物質 / アポセルロプラスミン欠損症 / チオバルビツール酸反応-陽性物質 / チオバルビツール酸反応陽性物質 / ヘファエスチン / 神経変性 / 酸化ストレス / 鉄酸化作用 / マンガン / 亜鉛トランスポーター / 亜鉛 / 肝細胞 / ライソゾーム / セラミド / 脳内鉄蓄積症 / 脂質代謝 / βアミロイド前駆体蛋白質 / アルツハイマー病 / 神経難病 … More Except Principal Investigator SLC19A3遺伝子 / ビタミンB1 / チアミントランスポーター / SLC19A3 遺伝子 / ウエルニッケ様脳症 / ビタミン B1 / 磁性 / MRI / 神経変性疾患 / 生体鉄 / ヒト脳 / 横緩和速度 / 高磁場MRI Less

Zinc effect for iron efflux from the neuronal cellsPrincipal Investigator
- Principal Investigator
  
  Miyajima Hiroaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hamamatsu University School of Medicine
Relationship between bioiron and neurodegenerative disease investigated through the proton relaxation rate by MRI
- Principal Investigator
  
  MITSUMORI Fumiyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  National Institute for Environmental Studies
Regulations on the brain iron cycle in the neurodegenerativedisordersPrincipal Investigator
- Principal Investigator
  
  MIYAJIMA Hiroaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hamamatsu University School of Medicine
Pathological mechanism in Wernicke's-like encephalopathy using SLC19A3 transgenic mouse
- Principal Investigator
  
  KONO Satoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hamamatsu University School of Medicine
Molecular basis of aceruloplasminemia : Expression of the ceruloplasmin gene in aceruloplasminemiaPrincipal Investigator
- Principal Investigator
  
  MIYAJIMA Hiroaki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hamamatsu University School of Medicine
CHARACTERIZATION OF MISSENSE MUTATIONS AND BIOCHEMICAL ANALYSIS OF INCREASED LIPID PEROXIDATION AND MITOCHONDRIAL DYSFUNCTION IN ACERULOPLASMINEMIAPrincipal Investigator
- Principal Investigator
  
  MIYAJIMA Hiroaki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
GENE ANALYSIS AND LIPID PEROXIDATION ASSOCIATED WITH INCREASED IRON IN PATIENTS WITH ACERULOPLASMINEMIAPrincipal Investigator
- Principal Investigator
  
  MIYAJIMA Hiroaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  HAMAMATU UNIVERSITY SCHOOL OF MEDECINE
INCREASED LIPID PEROXIDATION IN PATIENTS WITH ACERULOPLASMINEMIAPrincipal Investigator
- Principal Investigator
  
  MIYAJIMA Hiroaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
A mutation in the ceruloplasmin gene and increased lipid peroxidation in patients with familial apoceruloplasmin deficiencyPrincipal Investigator
- Principal Investigator
  
  MITAJIMA Hiroaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Hamamatsu University School of Medicine

All 2017 2016 2015 2014 2013 2012 2011 2010 2006 2005 2004 2003 Other

All Journal Article Presentation Book

[Book] Annual Review 神経 20172017
- Author(s)
  河野智、宮嶋裕明
- Total Pages
  281
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-26461291
[Book] 鉄剤の適正使用による貧血治療指針. 改訂[第３版]2015
- Author(s)
  林久男、宮嶋裕明
- Total Pages
  96
- Publisher
  響文社
- Data Source
  KAKENHI-PROJECT-26461291
[Book] Rosenberg’s Molecular and Genetic Basis of Neurological and Psychiatric Disease.2015
- Author(s)
  Kono S, Miyajima H
- Publisher
  Elsevier, Academic Press
- Data Source
  KAKENHI-PROJECT-26461291
[Book] 無セルロプラスミン血症の鉄過剰とその特徴. 「慢性肝炎における鉄毒性と除鉄治療..C 型慢性肝炎を中心に.日本鉄バイオサイエンス学会(編)」2012
- Author(s)
  河野智, 宮嶋裕明
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-22390238
[Book] 無セルロプラスミン血症の鉄過剰とその特徴.日本鉄バイオサイエンス学会(編)慢性肝炎における鉄毒性と除鉄治療.~C 型慢性肝炎を中心に~2012
- Author(s)
  河野智、宮嶋裕明
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-22590926
[Book] Neurodegenerative Diseases2005
- Author(s)
  Kono S., Miyajima H., Gitlin JD.
- Total Pages
  985
- Publisher
  Cambridge University Press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590885
[Book] Brain iron disorders, Neurodegenerative Diseases (Beal MF et al. (Editors))2005
- Author(s)
  Kono S., Miyajima H., Gitlin JD.
- Publisher
  Cambridge Univ.Press
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] Direct comparison of manganese detoxification/efflux proteins and molecular characterization of ZnT10 protein as a manganese transporter.2016
- Author(s)
  Nishito Y, Tsuji N, Fujishiro H, Takeda TA, Yamazaki T, Teranishi F, Okazaki F, Matsunaga A, Tuschl K, Rao R, Kono S, Miyajima H, Narita H, Himeno S, Kambe T.
- Journal Title
  
  J Biol Chem
  
  Volume: 291 Pages: 14773-14787
- NAID
  120006376011
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461291
[Journal Article] Aceruloplasminemia2015
- Author(s)
  Miyajima H
- Journal Title
  
  Neuropathol
  
  Volume: 35 Pages: 83-90
- NAID
  10008311253
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461291
[Journal Article] Copper accumulates in hemosiderins in livers of patients with iron overload syndromes.2015
- Author(s)
  Ono Y, Ishigami M, Hayashi K, Wakusawa S, Hayashi H, Kumagai K, Morotomi N, Yamashita T, Kawanaka M, Watanabe M, Ozawa H, Tai M, Miyajima H, Yoshioka K, Hirooka Y, Goto H.
- Journal Title
  
  J Clin Transl Hepatol
  
  Volume: 3 Pages: 85-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461291
[Journal Article] Investigated and available therapeutic options for treating aceruloplasminemia.2015
- Author(s)
  Miyajima H
- Journal Title
  
  Expert Opinion on Orphan Drugs
  
  Volume: 3 Issue: 9 Pages: 1011-1020
- DOI
  10.1517/21678707.2015.1067137
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461291
[Journal Article] Case of presymptomatic aceruloplasminemia treated with deferasirox2014
- Author(s)
  Tai M, Matsuhashi N, Ichii O, Suzuki T, Ejiri Y, Kono S, Terada T, Miyajima H, Harada M
- Journal Title
  
  Hepatol Res
  
  Volume: 44 Pages: 1253-1258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461291
[Journal Article] SPG3A-linked hereditary spastic paraplegia associated with cerebral glucose hypometabolism.2013
- Author(s)
  Terada T, Kono S, Ouchi Y, Yoshida K, Hamaya Y, Kanaoka S, Miyajima H
- Journal Title
  
  Ann Nucl Med
  
  Volume: 27(3) Issue: 3 Pages: 303-8
- DOI
  10.1007/s12149-012-0673-5
- NAID
  10031168098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590927, KAKENHI-PROJECT-23390287, KAKENHI-PROJECT-23659562
[Journal Article] Benign hereditary chorea: dopaminergic brain imaging in patients with a novel intronic NKX2.1 gene mutation2013
- Author(s)
  Konishi T, Kono S, Fujimoto M, Terada T, Matsushita K, Ouchi Y, Miyajima H
- Journal Title
  
  J Neurol
  
  Volume: 260(1) Issue: 1 Pages: 207-13
- DOI
  10.1007/s00415-012-6618-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590927
[Journal Article] チアミントランスポーター変異とWernicke encephalopathy2012
- Author(s)
  宮嶋裕明
- Journal Title
  
  ビタミン
  
  Volume: 86 Pages: 337-338
- Data Source
  KAKENHI-PROJECT-22590927
[Journal Article] Vitamin B1 と神経疾患 Wernicke 様脳症2012
- Author(s)
  河野智,白川健太郎,宮嶋裕明
- Journal Title
  
  (thiamine transporter gene mutation)神経内科
  
  Volume: 76 Pages: 248-254
- URL
  http://www.kahyo.com/item/S201203-763
- Data Source
  KAKENHI-PROJECT-22590927
[Journal Article] Subacute progressive ophthalmoplegia associated with dermatomyositis2012
- Author(s)
  Kono S, Bunai T, Terada T, Shimoyama K, Konishi T, Shirakawa K, MiyajimaH
- Journal Title
  
  J Neurol
  
  Volume: 259 Pages: 1982-1984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590926
[Journal Article] Editorial, Neurodegeneration with brain iron accumulation.2012
- Author(s)
  H. Miyajima
- Journal Title
  
  Curr. Drug Targets
  
  Volume: 13 Pages: 1181-1181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390238
[Journal Article] Combined FDG and raclopride PET study in a case of ALS with the R521C FUS gene mutation2012
- Author(s)
  Kono S, Ouchi Y, Terada T, Suzuki M, Yagi S, Miyajima H.
- Journal Title
  
  J Neurol
  
  Volume: 259 Pages: 367-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590926
[Journal Article] 脳内の鉄動態2012
- Author(s)
  宮嶋裕明
- Journal Title
  
  細胞
  
  Volume: 44 Pages: 5-7
- Data Source
  KAKENHI-PROJECT-22590926
[Journal Article] Neurodegeneration with brain iron accumulation2012
- Author(s)
  Miyajima H Editorial
- Journal Title
  
  Curr. Drug Targets
  
  Volume: 13 Pages: 1181-1181
- NAID
  40021622422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390238
[Journal Article] ビタミン学と神経疾患2012
- Author(s)
  宮嶋裕明
- Journal Title
  
  神経治療学
  
  Volume: 29 Pages: 155-159
- Data Source
  KAKENHI-PROJECT-22590927
[Journal Article] Combined FDG and raclopride PET study in a case of ALS with the R521C FUS gene mutation2012
- Author(s)
  Kono S, Ouchi Y, Terada T, Suzuki M, Yagi S, Miyajima H.
- Journal Title
  
  J Neurol
  
  Volume: 259(2) Issue: 2 Pages: 367-9
- DOI
  10.1007/s00415-011-6168-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590927
[Journal Article] Clinicopathological study of Japanese patients with genetic iron overload syndromes2012
- Author(s)
  Hattori A, Miyajima H, Tomosugi N, Tatsumi Y, Hayashi H, Wakusawa S
- Journal Title
  
  Pathol Int
  
  Volume: 62 Pages: 612-618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590926
[Journal Article] Clinicopathological study of Japanese patients with genetic iron overload syndromes2012
- Author(s)
  Hattori A, Miyajima H, Tomosugi N, Tatsumi Y, Hayashi H, Wakusawa S
- Journal Title
  
  Pathol
  
  Volume: 62 Pages: 612-618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390238
[Journal Article] A case of Epstein-Barr virus associated post-transplant lymphoproliferative disorder with CNS involvement: pathological findings at both biopsy and autopsy2011
- Author(s)
  Suzuki M, Kosugi I, Terada T, Shirakawa K, Suzuki H, Kono S, Miyajima H
- Journal Title
  
  Neuropathol
  
  Volume: 31 Pages: 440-445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390238
[Journal Article] Frontal lobe-mediated behavioral changes in amyotrophic lateral sclerosis: Are they independent of physical disabilities?2011
- Author(s)
  Terada T, Obi T, Yoshizumi M, Murai T, Miyajima H, Mizoguchi K
- Journal Title
  
  J Neurol Sci
  
  Volume: 309 Pages: 136-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590926
[Journal Article] A case of Epstein-Barr virus associated post-transplant lymphoproliferative disorder with CNS involvement: pathological findings at both biopsy and autopsy.2011
- Author(s)
  Suzuki M, Kosugi I, Terada T, Shirakawa K, Suzuki H, Kono S, Miyajima H
- Journal Title
  
  Neuropathol
  
  Volume: 31 Pages: 440-445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590926
[Journal Article] チアミントランスポーター変異と Wernicke encephalopathy(Wernicke encephalopathy に関する最近の話題」-ビタミン B1 による認知症の予防・治療-2011
- Author(s)
  宮嶋裕明
- Journal Title
  
  シンポジウム(平成 23 年度),ビタミン B研究委員会
  
  Volume: 86 Pages: 337-338
- Data Source
  KAKENHI-PROJECT-22590927
[Journal Article] 家族性ウェルニッケ類似脳症におけるチアミントランスポーターの遺伝子変異2011
- Author(s)
  宮嶋裕明
- Journal Title
  
  医学のあゆみ
  
  Volume: 237(12) Pages: 1132-1133
- URL
  http://www.de-hon.ne.jp/digital/bin/product.asp?sku=3030000000135800900P
- Data Source
  KAKENHI-PROJECT-22590927
[Journal Article] Functional brain imaging in glucocerebrosidase mutation carriers with and without parkinsonism2010
- Author(s)
  Kono S, Ouchi Y, Terada T, Ida H, Suzuki M, Miyajima H
- Journal Title
  
  Mov Disord
  
  Volume: 25 Pages: 1823-1829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590926
[Journal Article] Biological effects of mutant ceruloplasmin on hepcidin-mediated internalization of ferroportin2010
- Author(s)
  Kono S, Yoshida K, Tomosugi N, Terada T, Hamaya Y, Kanaoka S, Miyajima H
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1802(11) Issue: 11 Pages: 968-75
- DOI
  10.1016/j.bbadis.2010.07.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590927
[Journal Article] Functional brain imaging in glucocerebrosidase mutation carriers with and without parkinsonism.2010
- Author(s)
  Kono S, Ouchi Y, Terada T, Ida H, Suzuki M, Miyajima H.
- Journal Title
  
  Movement Disorders
  
  Volume: 49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590927
[Journal Article] Functional brain imaging in glucocerebrosidase mutation carriers with and without parkinsonism.2010
- Author(s)
  Kono S, Ouchi Y, Terada T, Ida H, Suzuki M, Miyajima H
- Journal Title
  
  Mov Disord.
  
  Volume: 25(12) Issue: 12 Pages: 1823-9
- DOI
  10.1002/mds.23213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590927
[Journal Article] 家族性 Wernicke 類似脳症2010
- Author(s)
  宮嶋裕明河野智
- Journal Title
  
  臨床神経
  
  Volume: 50 Pages: 855-857
- URL
  http://www.neurology-jp.org/Journal/public_pdf/050110855.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590927
[Journal Article] セルロプラスミンと鉄代謝調節.2010
- Author(s)
  宮嶋裕明
- Journal Title
  
  日本医師会雑誌
  
  Volume: 139 Pages: 306-306
- Data Source
  KAKENHI-PROJECT-22590926
[Journal Article] Biological effects of mutant ceruloplasmin on hepcidin-mediated internalization of ferroportin.2010
- Author(s)
  Kono S, Yoshida K, Tomosugi N, Terada T, Hamaya Y, Kanaoka S, Miyajima H.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1802 Pages: 968-975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590927
[Journal Article] Central diabetes insipidus and hypothalamic hypothyroidism associated with aceruloplasminemia2010
- Author(s)
  Watanabe M, Asai C, Ishikawa K, Kiyota A, Terada T, Kono S, Miyajima H, Okumura A.
- Journal Title
  
  Intern Med
  
  Volume: 49 Pages: 1581-1585
- NAID
  130000299583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590926
[Journal Article] Measurement of serum hepcidin-25 levels as a potential test for diagnosing hemochromatosis and related disorders2010
- Author(s)
  Kaneko Y, Miyajima H, Piperno A, Tomosugi N, Hayashi H, Morotomi N, Tsuchida KI, Ikeda T, Ishikawa A, Ota Y, Wakusawa S, Yoshioka K, Kono S, Pelucchi S, Hattori A, Tatsumi Y, Okada T, Yamagishi M
- Journal Title
  
  J Gastroenterol
  
  Volume: 45 Pages: 1163-1171
- NAID
  10027699891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590926
[Journal Article] Predominant ataxia, low ceruloplasmin, and absent K-F rings: hypoceruloplasminemia or Wilson's disease.2010
- Author(s)
  Mehta SH, Parekh SM, Prakash R, Morgan JC, Miyajima H, Sethi KD
- Journal Title
  
  Mov Disord
  
  Volume: 25 Pages: 2260-2261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590926
[Journal Article] Biological effects of mutant ceruloplasmin on hepcidin-mediated internalization of ferroportin.2010
- Author(s)
  Kono S, Yoshida K, Tomosugi N, Terada T, Hamaya Y, Kanaoka S, Miyajima H
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1802 Pages: 968-975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590926
[Journal Article] Biological effects of mutant ceruloplasmin on hepcidin-mediated internalization of ferroportin2010
- Author(s)
  Kono S, Yoshida K, Tomosugi N, Terada T, Hamaya Y, Kanaoka S, Miyajima H
- Journal Title
  
  Biochim. Biophys
  
  Volume: 1802 Pages: 968-975
- Data Source
  KAKENHI-PROJECT-22390238
[Journal Article] Measurement of serum hepcidin-25 levels as a potential test for diagnosing hemochromatosis and related disorders.2010
- Author(s)
  Kaneko Y, Miyajima H, et al.
- Journal Title
  
  J Gastroenterol
  
  Volume: 45 Pages: 1163-1171
- NAID
  10027699891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590926
[Journal Article] Molecular and pathological basis of aceruloplasminemia.2006
- Author(s)
  Kono S., Miyajima H
- Journal Title
  
  Biol. Res. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] Molecular and pathological basis of aceruloplasminemia2006
- Author(s)
  Kono S., Miyajima H
- Journal Title
  
  Biol.Res. (In press)
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] Extrapyramidal and cerebellar movement disorder in association with heterozygous ceruloplasmin gene mutation.2005
- Author(s)
  Kuhn J., Miyajima H., Takahashi Y., Kunath B., Hartmann-Klosterkoetter U., Copper-Mahkorn D., Schaefer M., Bewermeyer H
- Journal Title
  
  J.Neurol. 252(1)
  
  Pages: 111-113
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] Extrapyramidal and cerebellar movement disorder in association with heterozygous ceruloplasmin gene mutation.2005
- Author(s)
  Kuhn J., Miyajima H., Takahashi Y., et al.
- Journal Title
  
  J.Neurol. 252・1
  
  Pages: 111-113
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] Frontal lobe dysfunction associated with glucose hypometabolism in aceruloplasminemia.2005
- Author(s)
  Miyajima H., Takahashi Y., Kono S., et al.
- Journal Title
  
  J. Neurol. 252・8
  
  Pages: 996-997
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] Frontal lobe dysfunction associated with glucose hypometabolism in aceruloplasminemia.2005
- Author(s)
  Miyajima H., Takahashi Y., Kono S., Hishida A., Ishikawa K., Sakamoto M.
- Journal Title
  
  J.Neurol. 252(8)
  
  Pages: 996-997
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] セルロプラスミンとそのホモログ2005
- Author(s)
  宮嶋裕明
- Journal Title
  
  細胞 37・10
  
  Pages: 395-398
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] Extrapyramidal and cerebellar movement disorder in association with heterozygous ceruloplasmin gene mutation.2005
- Author(s)
  Kuhn J., Miyajima H., Takahashi Y., et al.
- Journal Title
  
  J. Neurol. 252・1
  
  Pages: 111-113
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] Molecular and pathological basis of aceruloplasminemia.2005
- Author(s)
  Kono S., Miyajima H.
- Journal Title
  
  Biol.Res. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] Biolchemical features of ceruloplasmin gene mutations linked to aceruloplasminemia.2005
- Author(s)
  Kono S., Suzuki H., Oda T., Miyajima H., Takahashi Y., Shirakawa K., Ishikawa K., Kitagawa M.
- Journal Title
  
  Neuromol.Med. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] Frontal lobe dysfunction associated with glucose hypometabolism in aceruloplasminemia.2005
- Author(s)
  Miyajima H., Takahashi Y., Kono S., et al.
- Journal Title
  
  J.Neurol. 252・8
  
  Pages: 996-997
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] セルロプラスミン遺伝子異常との関係,神経症状2004
- Author(s)
  宮嶋裕明
- Journal Title
  
  日本内科学会雑誌 93・8
  
  Pages: 1579-1584
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] セルロプラスミンと銅、鉄代謝2004
- Author(s)
  宮嶋裕明他
- Journal Title
  
  神経内科 61・2
  
  Pages: 130-139
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] 無セルロプラスミン血症.臨床医のための神経病理2004
- Author(s)
  宮嶋裕明
- Journal Title
  
  Clin Neurosci 22・4
  
  Pages: 368-369
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] Aceruloplasminemia, an inherited disorder of iron metabolism.2003
- Author(s)
  Miyajima H., Takahashi Y., Kono S
- Journal Title
  
  Biometals 16(1)
  
  Pages: 205-213
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] Aceruloplasminemia, an iron metabolic disorder.2003
- Author(s)
  Miyajima H.
- Journal Title
  
  Neuropathology 23(4)
  
  Pages: 345-350
- NAID
  10013405066
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] (Month of publication 2005): Aceruloplasminemia.
- Author(s)
  Miyajima H.
- Journal Title
  
  Gene Reviews at Gene Tests : Available at http://www.genetests.org.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590885
[Journal Article] ビタミン学と神経疾患
- Author(s)
  宮嶋裕明
- Journal Title
  
  神経治療学
- URL
  http://jglobal.jst.go.jp/public/20090422/201102260771318942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590927
[Presentation] 鉄代謝の解明に向けて～新たな創薬のターゲット～2015
- Author(s)
  宮嶋裕明
- Organizer
  第33回日本神経治療学会総会
- Place of Presentation
  名古屋
- Year and Date
  2015-11-26
- Invited
- Data Source
  KAKENHI-PROJECT-26461291
[Presentation] Iron mapping in human brain using apparent transverse relaxation rate and macromolecular mass-fraction obtained by multiecho adiabatic spin echo measurements2013
- Author(s)
  Mitsumori F, Watanabe H, Takaya N, Miyajima H
- Organizer
  ENC2013 (招待講演)
- Place of Presentation
  Asilomar
- Year and Date
  2013-04-16
- Data Source
  KAKENHI-PROJECT-22390238
[Presentation] 神経変性症における微量金属の役割 = 鉄蓄積性脳症、無セルロプラスミン血症を中心に=2012
- Author(s)
  宮嶋裕明
- Organizer
  第5回近畿亜鉛栄養治療研究会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-22590926
[Presentation] 神経変性疾患における鉄代謝2012
- Author(s)
  宮嶋裕明
- Organizer
  第36回日本鉄バイオサイエンス学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22390238
[Presentation] 神経変性疾患における鉄代謝2012
- Author(s)
  宮嶋裕明
- Organizer
  第36回日本鉄バイオサイエンス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2012-09-01
- Data Source
  KAKENHI-PROJECT-22590926
[Presentation] 神経変性症における微量金属の役割 = 鉄蓄積性脳症、無セルロプラスミン血症を中心に=2012
- Author(s)
  宮嶋裕明
- Organizer
  第5回近畿亜鉛栄養治療研究会.
- Place of Presentation
  大阪
- Year and Date
  2012-08-04
- Data Source
  KAKENHI-PROJECT-22590926
[Presentation] 神経変性症における微量金属の役割鉄蓄積性脳症、無セルロプラスミン血症を中心に2012
- Author(s)
  宮嶋裕明
- Organizer
  第5回近畿亜鉛栄養治療研究会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-22390238
[Presentation] 神経変性疾患無セルロプラスミン血症患者脳の鉄分布画像2012
- Author(s)
  三森文行, 渡邉英宏, 高屋展宏, 宮嶋裕明
- Organizer
  第40回日本磁気共鳴医学会大会
- Place of Presentation
  京都
- Year and Date
  2012-09-07
- Data Source
  KAKENHI-PROJECT-22390238
[Presentation] 脳内鉄と線維状タンパクの変性脳内疾病の原因ー2012
- Author(s)
  宮嶋裕明
- Organizer
  第42回繊維学会夏季セミナー「感動繊維の独創と共創」
- Place of Presentation
  浜松
- Year and Date
  2012-08-29
- Data Source
  KAKENHI-PROJECT-22590926
[Presentation] 脳と大脳基底核2011
- Author(s)
  宮嶋裕明
- Organizer
  第26回日本大脳基底核研究会
- Place of Presentation
  箱根
- Year and Date
  2011-07-02
- Data Source
  KAKENHI-PROJECT-22590926
[Presentation] 脳内鉄と線維状タンパクの変性2011
- Author(s)
  宮嶋裕明
- Organizer
  第42回繊維学会夏季セミナー「感動繊維の独創と共創」
- Place of Presentation
  浜松
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-22590926
[Presentation] 脳の鉄代謝調節とその破綻による神経変性症2011
- Author(s)
  宮嶋裕明
- Organizer
  第15回日本適応医学学会学術集会(招待講演)
- Place of Presentation
  浜松
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-22390238
[Presentation] 脳の鉄代謝調節とその破綻による神経変性症2011
- Author(s)
  宮嶋裕明
- Organizer
  第15回日本適応医学学会学術集会
- Place of Presentation
  浜松
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-22590926
[Presentation] 遺伝性dystonia-parkinsonism2011
- Author(s)
  宮嶋裕明
- Organizer
  Movement Disorder Society, Japan (MDSJ)第5回学術集会
- Place of Presentation
  東京
- Year and Date
  2011-10-06
- Data Source
  KAKENHI-PROJECT-22590926
[Presentation] 脳の鉄代謝調節とその破綻による神経変性症2011
- Author(s)
  宮嶋裕明
- Organizer
  第15回日本適応医学学会学術集会
- Place of Presentation
  浜松
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-22590926
[Presentation] ビタミン学と神経疾患2011
- Author(s)
  宮嶋裕明
- Organizer
  第29回日本神経治療学会総会
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-22590927
[Presentation] 単一遺伝子異常による遺伝性神経疾患:家族性ウエルニッケ様脳症2010
- Author(s)
  宮嶋裕明
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-22590927
[Presentation] 単一遺伝子異常による遺伝性神経疾患:家族性ウエルニッケ様脳症2010
- Author(s)
  宮嶋裕明
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  日東京国際フォーラム
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-22590927
[Presentation] Aceruloplasminemia
- Author(s)
  Miyajima H
- Organizer
  55th Annual Meeting of JSNP
- Place of Presentation
  Tokyo
- Year and Date
  2014-06-05 – 2014-06-07
- Invited
- Data Source
  KAKENHI-PROJECT-26461291

1. KONO Satoshi (40397386)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
2. TAKAHASHI Yoshitomo (90303560)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
3. SUZUKI Makiko (60549278)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. SHIMIZU Hideaki (70270981)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MITSUMORI Fumiyuki (90125229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. WATANABE Hidehiro (60370269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. SEYAMA Haruhiko (40142096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 米村克彦 (40252176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 清水貴子 (90206201)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Miyajima Hiroaki 宮嶋 裕明

MIYAJIMA Hiroaki 宮嶋 裕明

MITAJIMA Hiroaki 宮嶋 裕明

宮崎 裕明 ミヤザキ ヒロアキ

Research Projects

Research Products

Co-Researchers

Zinc effect for iron efflux from the neuronal cellsPrincipal Investigator

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Relationship between bioiron and neurodegenerative disease investigated through the proton relaxation rate by MRI

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Regulations on the brain iron cycle in the neurodegenerativedisordersPrincipal Investigator

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Pathological mechanism in Wernicke's-like encephalopathy using SLC19A3 transgenic mouse

Principal Investigator

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Molecular basis of aceruloplasminemia : Expression of the ceruloplasmin gene in aceruloplasminemiaPrincipal Investigator

Principal Investigator

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Research Institution

CHARACTERIZATION OF MISSENSE MUTATIONS AND BIOCHEMICAL ANALYSIS OF INCREASED LIPID PEROXIDATION AND MITOCHONDRIAL DYSFUNCTION IN ACERULOPLASMINEMIAPrincipal Investigator

Principal Investigator

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Research Institution

GENE ANALYSIS AND LIPID PEROXIDATION ASSOCIATED WITH INCREASED IRON IN PATIENTS WITH ACERULOPLASMINEMIAPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

INCREASED LIPID PEROXIDATION IN PATIENTS WITH ACERULOPLASMINEMIAPrincipal Investigator

Principal Investigator

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Research Institution

A mutation in the ceruloplasmin gene and increased lipid peroxidation in patients with familial apoceruloplasmin deficiencyPrincipal Investigator

Principal Investigator

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[Book] Annual Review 神経 20172017

Author(s)

Total Pages

Publisher

Data Source

[Book] 鉄剤の適正使用による貧血治療指針. 改訂[第３版]2015

Author(s)

Total Pages

Publisher

Data Source

[Book] Rosenberg’s Molecular and Genetic Basis of Neurological and Psychiatric Disease.2015

Author(s)

Publisher

Data Source

[Book] 無セルロプラスミン 血症の鉄過剰とその特徴. 「慢性肝炎に おける鉄毒性と除鉄治療..C 型慢性肝 炎を中心に.日本鉄バイオサイエンス 学会(編)」2012

Author(s)

Publisher

Data Source

[Book] 無セルロプラスミン血症の鉄過剰とその特徴.日本鉄バイオサイエンス学会(編)慢性肝炎における鉄毒性と除鉄治療.~C 型慢性肝炎を中心に~2012

Miyajima Hiroaki 宮嶋裕明

MIYAJIMA Hiroaki 宮嶋裕明

MITAJIMA Hiroaki 宮嶋裕明

宮崎裕明ミヤザキヒロアキ

[Book] 無セルロプラスミン血症の鉄過剰とその特徴. 「慢性肝炎における鉄毒性と除鉄治療..C 型慢性肝炎を中心に.日本鉄バイオサイエンス学会(編)」2012