NISHIMURA Junji 西村淳二

Researcher Number	90237727
Other IDs
Affiliation (based on the past Project Information) *help	2006: 九大, 医学(系)研究科(研究院), 助教授 2000 – 2005: KYUSHU UNIVERSITY, Graduate School of Medical Sciences, Ass Professor, 大学院・医学研究院, 助教授 1999: 九州大学, 大学院・医学系研究科, 助教授 1996 – 1998: KYUSHU UNIVERSITY,FACULTY OF MEDICINE,ASSOCIATE PROFESSOR, 医学部, 助教授 1992 – 1995: 九州大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / 血管生物学 / General pharmacology Except Principal Investigator Circulatory organs internal medicine / Urology / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator 血管平滑筋 / カルシウム / 低分子量G蛋白 / Molecular Biology / Calcium Ion / 分子生物学 / Cell culture / RhoA / Collagen gel / Virus vector … More / Contraction / Vascular smooth muscle / ウイルスベクター / コラーゲンゲル / 細胞培養 / 収縮 / MYOSIN PHOSPHATASE / CALCIUM / VASCULAR TONE / CALCIUM SENSITIVITY / SMALL GPROTEIN / VASCULAR SMOOTH MUSCLE / ミオシン軽鎖脱リン酸化酵素 / 血管緊張 / カルシウム感受性 / Endothelin / Adrenomedullin / Autocrine / Biologically active peptides / 血管増殖 / エンドセリン / アドレノメジュリン / オートクリン / 生理活性ペプチド / Cell Proliferation / Muscle Contraction / Vascular Smooth Muscle / 細胞増殖 / 筋収縮 / カルシウムイオン / 交換機構 / ナトリウム / 平滑筋 / 血管 … More Except Principal Investigator 血管平滑筋細胞 / 血管内皮細胞 / fura-2 / 血管平滑筋 / BCECF / vascular smooth muscle cells / 内皮細胞 / Protein kinase C / Rho kinase / Ca^<2+> signaling / トロンビン / Ca^<2+>シグナリング / Ca^<2+>感受性 / 細胞シグナル伝達 / endothelial cells / 細胞増殖 / ミオシン脱燐酸化酵素 / vascular smooth muscle / カルシウム感受性 / 血管緊張 / フラ-2 / 細胞質カルシウム / 細胞周期 / エンドセリン / 細胞カルシウム濃度 / Human prostate / Carbachol / Ca sensitization / Human detrusor smooth muscle / Intracellular Ca concentration / 過活動膀胱 / ヒト前立腺 / カルバコール / ヒト排尿筋 / 細胞内カルシウム / Broncheal asthma / Cell culture / Collagen gel / Small G protein / Contraction / Airway smooth muscle / 培養細胞 / 気管支喘息 / 低分子量G蛋白 / ウイルスベクター / コラーゲンゲル / 細胞培養 / 収縮 / 気道平滑筋 / (pH)I / intracellular signalings / Na^+ / 〔pH〕i / HMG-CoA還元酵素 / [pH]i / myosin phosphatase / myosin phosphorylation / subarachnoid hemorrhage / thrombin / vasospasm / Ca^<2+> sensitization / Y27632 / Rho-Kinase / MYPT1 / TAT-Protein / 細胞質Ca^<2+>濃度 / ミオシン軽鎖燐酸化 / 細胞質[Ca^<++>]i / トロンビン受容体 / Protease-actvated receptors / ミオシン燐酸化 / クモ膜下出血 / 血管攣縮 / CYTOSKELETON / CELL PROLIFERATION / Ca^<2+> SENSITIVITY / VASCULAR ENDOTHELIAL CELL / VASCULAR SMOOTH MUSCLE / REGULATORY SUBUNIT / PROTEIN PHOSPHATASE / MYOSIN / 血管構築 / 細胞骨格 / 調節サブユニット / 脱リン酸化酵素 / ミオシン / regulation of vascular tonus / optical fibers / vascular sooth muscle cells / intracellular signaling network / 容量依存性性カルシウム流入 / タプシガルギン / 血管緊張調節 / 光学線維束 / intracellular signal transduction networks / cell cycle / calcium signaling / intimal thickening / coronary spasm / 細胞情報伝達 / 冠血管形成術 / 細胞増殖接触抑制 / 血管管腔形成 / 細胞情報伝達網 / カルシウムシグナリング / 内膜肥厚 / 冠動脈攣縮 / cytosolic calcium concentration / measurements in vivo / Vascular endothelial cells / フラ-ス / 生体計測 / 血管内皮 / calcium sensitivity / vasorelaxation / vasoconstriction / cell calcium / 血管〓縮 / cyclic AMP / エンドセリン受容体 / 細胞質カルシウム濃度 / 血管拡張 / 血管拡張薬 / 細胞カルシウム / Endothelium-derived relaxing factor(EDRF) / Endothelin / GTP-binding protein / Ethanol / Myocardial cells / Endothelial cells in situ / Vascular smooth muscle cells / Fura-2 / 細胞膜Ca^<++>濃度 / カプトリル / フラー2 / EDRF / G蛋白質 / 内皮由来弛緩因子(EDRF) / GTP結合蛋白質 / エタノール / 心筋細胞 / 血管拘縮 / Protein kinase A / 血管リモデリング / GF10920X / CPI-17 / Protein inase C / Rho-kinase / NIH3T3細胞 / 血管モデル / 線維芽細胞 / チロシンリン酸化 / カルシウムチャネル / 百日咳毒素 / G蛋白 Less

血管平滑筋におけるNa-Ca交換機構の役割:過剰発現マウスを用いた解析Principal Investigator
- Principal Investigator
  
  西村淳二
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kyushu University
Ca^<2+> sensitization of human and rabbit urinary bladder smooth muscle
- Principal Investigator
  
  SEKI Narihito
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  KYUSHU UNIVERSITY
内皮・平滑筋・繊維芽細胞の三次元共培養による血管構築を摸した血管モデルの作製
- Principal Investigator
  
  金出英夫
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Molecular mechanisms of vasospasm : Intracellular signaling network underlying the Ca^<2+> of smooth muscle cells.
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Development of a system for the continuous and simultaneous measurement of vascular intracellular signalings and metabolism
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
The assessment of the contractility of the proliferating airway smooth muscle.
- Principal Investigator
  
  SETOGUCHI Hidekazu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kyushu University
The assessment of the contractility of the proliferating vascular smooth musclePrincipal Investigator
- Principal Investigator
  
  NISHIMURA Junji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  Kyushu University
Elucidation of the physiological role of myosin phosphatase in vascular endothelial cells and smooth muscle cells
- Principal Investigator
  
  HIRANO Katsuya, 周応畢
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
The role of the small GTP binding protein, rho, in the vascular smooth muscle.Principal Investigator
- Principal Investigator
  
  NISHIMURA Junji
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  KYUSHU UNIVERSITY
Development of the optical system for continuous and multi-factorial monitoring of the intracellular signaling network in endothelial and smooth muscle cells in vascular strips.
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
AUTOCRINE AND PARACRINE REGULATION OF VASCULAR SMOOTH MUSCLE PROLIFERATION AND TONE BY THE BIOLOGICALLY ACTIVE PEPTIDES.Principal Investigator
- Principal Investigator
  
  NISIMURA Junji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Studies on molecular cell biology of the inhibition of coronary vasoconstriction and intimal thickening.
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
細胞周期制御におけるカルシウム情報伝達系の意義:特に血管内皮・平滑筋細胞について
- Principal Investigator
  
  小林誠
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
TO DEVELOP A NEW SYSTEM TO CONTIMUOUSLY MONITOR THE FUNCTIONS AT THE CELLULAR AND MOLECULAR LEVELS OF THE VASCULAR ENDOTHELIAL AND SMOOTH MUSCLE CELLS IN VIVO.
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
MECHANISMS FOR THE ACTION OF VASOACTIVE SUBSTANCES AND GROWTH FACTORS.Principal Investigator
- Principal Investigator
  
  NISHIMURA Junji
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  血管生物学
- Research Institution
  KYUSHU UNIVERSITY
血管機能の調節における内皮および平滑筋細胞情報伝達系の相互作用
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
THE PATHOGENESIS OF AN INCREASE IN VASCULAR TONUS : THE DEVELOPMENT OF NEW VASODILATORS.
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
THE DEVELOPMENT AND THE CLINICAL APPLICATION OF AN OPTICAL SYSTEM FOR THE SIMULTANEOUS DETERMINATION OF METABOLIC AND FUNCTIONAL CHANGES IN THE HEART AND BLOOD VESSELS.
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY

All 2004 2003

All Journal Article

[Journal Article] Ca^<2+> sensitization in contraction of human bladder smooth muscle.2004
- Author(s)
  Takahashi R, Nishimura J, Hirano K, Seki N, Naito S, Kanaide H
- Journal Title
  
  J Urol 172
  
  Pages: 748-752
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591694
[Journal Article] The modulation of Ca^<2+> sensitivity regulates contractility of rabbit corpus cavernosum smooth muscle.2003
- Author(s)
  Takahashi R, Nishimura J, Hirano K, Naito S, Kanaide H
- Journal Title
  
  J.Urol 169
  
  Pages: 2412-2416
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591694
[Journal Article] Protein kinase network in the regulation of phosphorylation and dephosphorylation of smooth muscle myosin light chain.2003
- Author(s)
  J.Nishimura et al.
- Journal Title
  
  Mol.Cell.Biochem. 248
  
  Pages: 105-114
- Data Source
  KAKENHI-PROJECT-15591694
[Journal Article] The modulation of Ca^<2+> sensitivity fegulates contractility of rabbit corpus cavernosum smooth muscle.2003
- Author(s)
  J.Nishimura et al.
- Journal Title
  
  J.Urol. 169
  
  Pages: 2412-2416
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591694
[Journal Article] The modulation of Ca^<2+> sensitivity regulates contractility of rabbit corpus2003
- Author(s)
  J.Nishimura et al.
- Journal Title
  
  J.Urol. 169
  
  Pages: 2412-2416
- Data Source
  KAKENHI-PROJECT-15591694

1. KANAIDE Hideo (80038851)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. HIRANO Katsuya (80291516)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
3. KOBAYASHI Sei (80225515)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. SETOGUCHI Hidekazu (20325525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SEKI Narihito (90294941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 周応畢 (80294916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NISHIMURA Junji 西村 淳二

Research Projects

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Co-Researchers

血管平滑筋におけるNa-Ca交換機構の役割:過剰発現マウスを用いた解析Principal Investigator

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The assessment of the contractility of the proliferating vascular smooth musclePrincipal Investigator

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The role of the small GTP binding protein, rho, in the vascular smooth muscle.Principal Investigator

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AUTOCRINE AND PARACRINE REGULATION OF VASCULAR SMOOTH MUSCLE PROLIFERATION AND TONE BY THE BIOLOGICALLY ACTIVE PEPTIDES.Principal Investigator

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MECHANISMS FOR THE ACTION OF VASOACTIVE SUBSTANCES AND GROWTH FACTORS.Principal Investigator

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NISHIMURA Junji 西村淳二