• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

NAWA Akihiro  那波 明宏

ORCIDConnect your ORCID iD *help
… Alternative Names

那波 明宏  ナワ アキヒロ

Less
Researcher Number 90242859
Affiliation (based on the past Project Information) *help 2018 – 2021: 名古屋大学, 医学系研究科, 特任教授
2017: 名古屋大学, 医学(系)研究科(研究院), 特任教授
2016: 名古屋大学, 医学系研究科, 特任教授
2015: 名古屋大学, 医学(系)研究科(研究院), 教授
2015: 名古屋大学, 医学(系)研究科(研究院), 特任教授 … More
2012 – 2014: 愛媛大学, 医学(系)研究科(研究院), 教授
2013: 愛媛大学, 大学院医学系研究科, 教授
2011 – 2012: 愛媛大学, 医学系研究科, 教授
2011: 愛媛大学, 大学院・医学系研究科, 教授
2010: 名古屋大学, 医学系研究科, 准教授
2009: 名古屋大学, 大学院・医学系研究科, 教授
2007 – 2009: Nagoya University, 大学院・医学系研究科, 准教授
2005: Nagoya University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授
2001 – 2004: 愛知県がんセンター, 研究所, 研究員
1997 – 1998: 名古屋大学, 医学部, 助手
1993: 名古屋大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology / Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related
Except Principal Investigator
Obstetrics and gynecology
Keywords
Principal Investigator
卵巣癌 / 腫瘍溶解性ウイルス / 葉酸受容体 / PCFT / パクリタキセル / 分子標的薬 / シクロデキストリン / syncytial formation / 葉酸 / 腫瘍溶解性ヘルペスウイルス … More / FOLR1 / 卵巣癌腹膜播種 / ovarian cancer / がん幹細胞 / carrier cell / 腫瘍溶解性ウイルス療法 / HSVアンプリコン / 化学療法抵抗性 / 癌微小環境 / FRα / SLCO2B1 / 尿毒素 / 腎毒性 / 抗がん剤 / 1型単純ヘルペスウイルス / シスプラチン / プロトン-葉酸共輸送担体 / 化学療法 / インドキシル硫酸 / 抗癌剤 / 人工エンベロープ被覆技術 / 人口エンベロープ被膜技術 / がん-間質クロストーク / 卵巣がん腹膜播種 / 機能性腫瘍溶解性ウイルス / R3616 / HSV-1 / clear cell carcinoma cells of the ovary / MDR expressing cells / taxol prodrug / rabbit-carboxyl esterase / HSV amplicon / Rabbit Carboxylesterase / タキソール プロドラッグ / MDR / Rabbit carboxylesterase / アンプリコン / タキソール ブロドラック / HSV / rabbit-carboxlesterase / 卵巣clear cell carcinoma細胞 / MDR発現細胞 / タキソールプロドラッグ / rabbit-carboxylesterase / apoptosis / mouse model / peritoneally disseminated neoplasm / herpes simplexvirus type1 mutant / replication-competent / 増殖型HSVI変異株 / immuno-competent mouse / アポトーシス / 同系移植マウスモデル / ヌードマウスモデル / 腹膜播種 / 増殖型HSV1型変異株 / 葉酸ーFITC / 葉酸レセプターα / 高分子ポリマー修飾 / 腹膜播種卵巣癌 / ナノコーティング / 腹膜播種モデルマウス / 葉酸レセプター / HF10 / ナノポリマー修飾 / intraperitoneal therapy / cell-to-cell / herpes simplex virus / dissemination / oncolytic virotherapy / OATP8siRNA / Lenti virus vector / h-TERT-promoter / realtime RT-PCR / Taxol / OATP8 / 薬剤耐性 / タキソール / OATP8遺伝子 / CD133陽性細胞 / 抗腫瘍性増強 / 卵巣癌腹膜播種病変 / VEGF / アバスチン / 大網中皮細胞 / HSV HF10 / ウイスル療法 / 抗VEGF療法 / Carrier Cell / GM-CSF / ウイルス療法 / phosphorothioate antisense oligo / MMP-9 / インテグリン-FAK-Ras path way / MAPK / dominant-negative Ras / FAK / MMP9 / フィブロネクチン / 卵巣癌細胞株 / HLA typing / リンパ節転移 / HPV / 外陰癌 / 子宮頸癌 … More
Except Principal Investigator
CD133 / 癌幹細胞 / 腹膜播種 / TGF-β / 上皮間葉転換 / 卵巣癌 / トランスジェニックマウス / 動物モデル / 子宮頸癌 / 腫瘍発生学 / マウス / トロホブラスト / HMGA1 / 高血圧 / 絨毛細胞 / 血管内皮 / 妊娠高血圧症候群 / Lgr4 / 雌生殖器分化 / 性分化 / glypican3 / 臨床試験 / ペプチドワクチン / 卵巣明細胞腺癌 / 卵巣がん幹細胞 / Glypican-3 / 免疫療法 / CXCR-4 / 腹膜中皮 / CXCR4 / ニッチ / α-SAM / がん幹細胞 / 幹細胞ニッチ / 腹膜中皮細胞 / タキソール / 薬剤耐性 / RNA-i / 形態変化 / RNA-干渉 / TWIST / 上皮間葉転換(EMT) / paclitaxel / 転移 / 抗がん剤 / 耐性化 / 再発・再燃 / 抗癌剤耐性 / 転移浸潤 / 上皮間葉転換現象 / 上皮性卵巣癌 Less
  • Research Projects

    (15 results)
  • Research Products

    (68 results)
  • Co-Researchers

    (22 People)
  •  Development of modified oncolytic virus targeting refractory relapsed ovarian tumorPrincipal Investigator

    • Principal Investigator
      Nawa Akihiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Nagoya University
  •  Development of new strategic oncolytic virotherapy for advanced ovarian cancerPrincipal Investigator

    • Principal Investigator
      Nawa Akihiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Nagoya University
  •  Role of HMGA1 on the pathogenesis of preeclampsia

    • Principal Investigator
      Matsubara Keiichi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Ehime University
  •  Roles of growth factors and oncogenes on cervical carcinogenesis in transgenic mice

    • Principal Investigator
      Takashi Matsumoto
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Ehime University
  •  Establishment of polymer-equipped oncolytic virotherapeutics against ovarian cancer.Principal Investigator

    • Principal Investigator
      NAWA Akihiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Nagoya University
      Ehime University
  •  Analysis of Lgr4 function and development of anti-LGR4 antibody drug in gynecology

    • Principal Investigator
      KOIZUMI MASAE
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Ehime University
  •  Combination of stem cell research and immunotherapy in gynecologic cancer

    • Principal Investigator
      KIKKAWA Fumitaka
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Nagoya University
  •  The development of the new cancer virus, cell therapy for ovarian cancer and the analysis of immune system responsePrincipal Investigator

    • Principal Investigator
      NAWA Akihiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Ehime University
      Nagoya University
  •  Characteristic of gynecologic cancer stem cell and Epithelial-Mesenchymal Transition

    • Principal Investigator
      KIKKAWA Fumitaka
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Nagoya University
  •  New strategy for the enhanced chemosensitivity and less metastatic potential of ovarian cancer targeting EMT inducible transcriptional factor

    • Principal Investigator
      KIKKAWA Fumitaka
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Nagoya University
  •  Development of a novel oncolytic virotherapy for ovarian cancer and primary peritoneal serous carcinomaPrincipal Investigator

    • Principal Investigator
      NAWA Akihiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Nagoya University
  •  The development of a novel genetherapy for pelitoneal dissemination of ovarian cancer using HSV-1 and its amplicon system.Principal Investigator

    • Principal Investigator
      NAWA Akihiro
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Nagoya University
      Aichi Cancer Center Research Institute
  •  Oncolytic viral therapy for disseminated peritoneal ovarian cancer using a novel replication-competent herpes simplex virus type 1 mutant in mice.Principal Investigator

    • Principal Investigator
      NAWA Akihiro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Aichi Cancer Center
  •  卵巣癌の浸潤促進に関与する接着分子を介した細胞内情報伝達機構の解析Principal Investigator

    • Principal Investigator
      那波 明宏
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Nagoya University
  •  婦人科癌でのリンパ節転移評価におけるHPV遺伝子検索の臨床的意義の解明Principal Investigator

    • Principal Investigator
      那波 明宏
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Nagoya University

All 2022 2021 2020 2019 2018 2016 2015 2012 2011 2010 2009 2008 2007 2005 2003

All Journal Article Presentation

  • [Journal Article] Peritoneal restoration by repurposing vitamin D inhibits ovarian cancer dissemination via blockade of the TGF-β1/thrombospondin-1 axis2022

    • Author(s)
      Kitami Kazuhisa、Yoshihara Masato、Tamauchi Satoshi、Sugiyama Mai、Koya Yoshihiro、Yamakita Yoshihiko、Fujimoto Hiroki、Iyoshi Shohei、Uno Kaname、Mogi Kazumasa、Ikeda Yoshiki、Yokoi Akira、Yoshikawa Nobuhisa、Nishino Kimihiro、Niimi Kaoru、Nawa Akihiro、Enomoto Atsushi、Kajiyama Hiroaki
    • Journal Title

      Matrix Biology

      Volume: 109 Pages: 70-90

    • DOI

      10.1016/j.matbio.2022.03.003

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09751, KAKENHI-PROJECT-19K18693, KAKENHI-PROJECT-20K22806, KAKENHI-PROJECT-19H03797, KAKENHI-PROJECT-21H03075, KAKENHI-PROJECT-21K09492, KAKENHI-PROJECT-21K19562, KAKENHI-PROJECT-21K16788, KAKENHI-PROJECT-22K20801, KAKENHI-PROJECT-21KK0296, KAKENHI-PROJECT-21KK0157, KAKENHI-PROJECT-20H03824, KAKENHI-PROJECT-23K24110
  • [Journal Article] Metastatic Voyage of Ovarian Cancer Cells in Ascites with the Assistance of Various Cellular Components2022

    • Author(s)
      Uno Kaname、Iyoshi Shohei、Yoshihara Masato、Kitami Kazuhisa、Mogi Kazumasa、Fujimoto Hiroki、Sugiyama Mai、Koya Yoshihiro、Yamakita Yoshihiko、Nawa Akihiro、Kanayama Tomohiro、Tomita Hiroyuki、Enomoto Atsushi、Kajiyama Hiroaki
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 8 Pages: 4383-4383

    • DOI

      10.3390/ijms23084383

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09751, KAKENHI-PROJECT-21K09492, KAKENHI-PROJECT-22K18390, KAKENHI-PROJECT-21K19562, KAKENHI-PROJECT-21K16788, KAKENHI-PROJECT-22K20801, KAKENHI-PROJECT-21KK0296, KAKENHI-PROJECT-21KK0157, KAKENHI-PROJECT-20H03824
  • [Journal Article] Ovarian Cancer-Associated Mesothelial Cells: Transdifferentiation to Minions of Cancer and Orchestrate Developing Peritoneal Dissemination2021

    • Author(s)
      Mogi K, Yoshihara M, Iyoshi S, Kitami K, Uno K, Tano S, Koya Y, Sugiyama M, Yamakita Y, Nawa A, Tomita H, Kajiyama H.
    • Journal Title

      Cancers (Basel).

      Volume: 13 Issue: 6 Pages: 1352-1352

    • DOI

      10.3390/cancers13061352

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03824, KAKENHI-PROJECT-19K09751, KAKENHI-PROJECT-21K09492
  • [Journal Article] Pro‐tumoral behavior of omental adipocyte‐derived fibroblasts in tumor microenvironment at the metastatic site of ovarian cancer2021

    • Author(s)
      Iyoshi Shohei、Yoshihara Masato、Nakamura Kae、Sugiyama Mai、Koya Yoshihiro、Kitami Kazuhisa、Uno Kaname、Mogi Kazumasa、Tano Sho、Tomita Hiroyuki、Kajiwara Keiji、Taki Masayasu、Yamaguchi Shigehiro、Nawa Akihiro、Kajiyama Hiroaki
    • Journal Title

      International Journal of Cancer

      Volume: 149 Issue: 11 Pages: 1961-1972

    • DOI

      10.1002/ijc.33770

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09751, KAKENHI-PROJECT-19H02849, KAKENHI-PROJECT-20H03824, KAKENHI-PROJECT-20K09640, KAKENHI-PROJECT-21K09492, KAKENHI-PROJECT-21K19562, KAKENHI-PROJECT-21K16788, KAKENHI-PROJECT-21KK0157
  • [Journal Article] Filopodia play an important role in the trans-mesothelial migration of ovarian cancer cells2020

    • Author(s)
      Masato Yoshihara, Yoshihiko Yamakita, Hiroaki Kajiyama, Takeshi Sengae,Yoshihiro Koya, Mamoru Yamashita, Akihiro Nawa, Fumitaka Kikkawa
    • Journal Title

      Experimental Cell Research

      Volume: 392 Issue: 2 Pages: 112011-112011

    • DOI

      10.1016/j.yexcr.2020.112011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09751, KAKENHI-PROJECT-19H03797
  • [Journal Article] A folate‐appended cyclodextrin carrier targets ovarian cancer cells expressing the proton‐coupled folate transporter2020

    • Author(s)
      Saito Shinichi、Koya Yoshihiro、Kajiyama Hiroaki、Yamashita Mamoru、Kikkawa Fumitaka、Nawa Akihiro
    • Journal Title

      Cancer Science

      Volume: N/A Issue: 5 Pages: 1794-1804

    • DOI

      10.1111/cas.14379

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H05462, KAKENHI-PROJECT-19K09751
  • [Journal Article] Ovarian cancer-associated mesothelial cells induce acquired platinum-resistance in peritoneal metastasis via the FN1/Akt signaling pathway.2020

    • Author(s)
      Yoshihara M, Kajiyama H, Yokoi A, Sugiyama M, Koya Y, Yamakita Y, Liu W, Nakamura K, Moriyama Y, Yasui H, Suzuki S, Yamamoto Y, Ricciardelli C, Nawa A, Shibata K, Kikkawa F
    • Journal Title

      Int J Cancer

      Volume: 146 Issue: 8 Pages: 2268-2280

    • DOI

      10.1002/ijc.32854

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04338, KAKENHI-PROJECT-19K09751, KAKENHI-PROJECT-20K22806, KAKENHI-PROJECT-19H03797, KAKENHI-PROJECT-20H03824
  • [Journal Article] Hematopoietic lineage cell-specific protein 1 (HS1), a hidden player in migration, invasion, and tumor formation, is over-expressed in ovarian carcinoma cells2018

    • Author(s)
      Koya Yoshihiro, Liu Wenting, Yamakita Yoshihiko, Senga Takeshi, Shibata Kiyosumi, Yamashita Mamoru, Nawa Akihiro, Kikkawa Fumitaka, Kajiyama Hiroaki
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 66 Pages: 32609-32623

    • DOI

      10.18632/oncotarget.25975

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15705
  • [Journal Article] Clinical investigation of the safety and efficacy of a cervical intraepithelial neoplasia treatment using a hyperthermia device that uses heat induced by alternating magnetic fields.2016

    • Author(s)
      Koji Koizumi, Toru Fujioka, Toshiaki Yasuoka, Aya Inoue, Yuka Uchikura, Hiroki Tanaka, Katsuko Takagi, Miki Mori, Masae Koizumi, Hisashi Hashimoto, Takashi Matsumoto, Yuko Matsubara, Keiichi Matsubara, Akihiro Nawa
    • Journal Title

      Molecular and Clinical Oncology

      Volume: 13 Issue: 2 Pages: 310-316

    • DOI

      10.3892/mco.2016.929

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462528
  • [Journal Article] Lgr4 Controls Specialization of Female Gonads in Mice2015

    • Author(s)
      Koizumi, M. Oyama,K, Yamakami,Y, Kida,T, Satoh,R, Kato,S, Hidema,S, Oe,T, Goto,T, Clevers,H, Nawa,A, Nishimori,K
    • Journal Title

      Biol Reprod

      Volume: 93 Issue: 4 Pages: 1-11

    • DOI

      10.1095/biolreprod.114.123638

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H02442, KAKENHI-PROJECT-25462597
  • [Journal Article] Compensatory increase of left atrial external work to left ventricular dysfunction caused by afterload increase2015

    • Author(s)
      Inoue K, Asanuma T, Masuda K, Sakurai D, Higaki J, Nakatani S
    • Journal Title

      Am J Physiol Heart Circ Physiol.

      Volume: 308 Issue: 3 Pages: 4600-4614

    • DOI

      10.3390/ijms16034600

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461112, KAKENHI-PROJECT-26462493, KAKENHI-PROJECT-25462597
  • [Journal Article] Spectrin αII and ssII tetramers contribute to platinum anticancer drug resistance in ovarian serous adenocarcinoma2012

    • Author(s)
      Maeda O, Shibata K, Hosono S, Fujiwara S, Kajiyama H, Ino K, Nawa A, Tamakoshi K, Kikkawa F
    • Journal Title

      Int J Cancer

      Volume: 130 Pages: 113-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592128
  • [Journal Article] Carrier cell-based delivery of replication-competent HSV-1 mutants enhances antitumor effect for ovarian cancer.2011

    • Author(s)
      Fujiwara S, Nawa A, Luo CH, Kamakura M, Goshima F, Kondo C, Kiyono T, Kikkawa F, Nishiyama Y.
    • Journal Title

      Cancer Gene Ther.

      Volume: 18 Pages: 77-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592128
  • [Journal Article] Establishment of cisplatin-resistant ovarian yolk sac tumor cells and investigation, of the mechanism of cisplatin resistance using this cell line2011

    • Author(s)
      Shibata K, Umezu T, Sakurai M, Kajiyama H, Yamamoto E, Ino K, Nawa A, Kikkawa F
    • Journal Title

      Gynecol Obstet Invest

      Volume: 71 Pages: 104-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592128
  • [Journal Article]2010

    • Author(s)
      藤原多子、那波明宏、五島典、西山幸廣
    • Journal Title

      Medical Bio(Ohmusha)

      Pages: 40-46

    • Data Source
      KAKENHI-PROJECT-21592128
  • [Journal Article] Fertility-sparing surgery in young women with invasive epithelial ovarian cancer2010

    • Author(s)
      Kajiyama H, Shibata K, Suzuki S, Ino K, Nawa A, Kawai M, Nagasaka T, Kikkawa F
    • Journal Title

      Eur J Surg Oncol (in press)

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Identification and characterization of cancer stem cells in ovarian yolk sac tumors2010

    • Author(s)
      Suzuki S, Terauchi M, Umezu T, Kajiyama H, Shibata K, Nawa A, Kikkawa F
    • Journal Title

      Cancer Sci

      Volume: 101(10) Pages: 2179-85

    • NAID

      10027832399

    • Data Source
      KAKENHI-PROJECT-21659383
  • [Journal Article] Thyroid transcription factor 1 expression in ovarian carcinomas is an independent prognostic factor2010

    • Author(s)
      Fujiwara S, Nawa A, Nakanishi T, Shimoyama Y, Kajiyama H, Shibata K, Ino K, Nakamura S, Kikkawa F, Yatabe Y
    • Journal Title

      Hum Pathol (in press)

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Thyroid transcription factor 1 expression in ovarian carcinomas is an independent prognostic factor.2010

    • Author(s)
      Fujiwara S, Nawa A, Nakanishi T, Shimoyama Y, Kajiyama H, Shibata K, Ino K, Nakamura S, Kikkawa F, Yatabe Y.
    • Journal Title

      Hum Pathol. 41

      Pages: 560-565

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592128
  • [Journal Article] Thyroid transcription factor 1 expression in ovarian carcinomas is an independent prognostic factor.2010

    • Author(s)
      Fujiwara S, Nawa A, Nakanishi T, Shimoyama Y, Kajiyama H, Shibata K, Ino K, Nakamura S, Kikkawa F, Yatabe Y.
    • Journal Title

      Hum Pathol.

      Volume: 41 Pages: 560-565

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592128
  • [Journal Article] Gene silencing of glypican-3 in clear cell carcinoma of the ovary renders it more sensitive to the apoptotic agent paclitaxel in vitro and in vivo2010

    • Author(s)
      Umezu T, Shibata K, Shimaoka M, Kajiyama H, Yamamoto E, Ino K, Nawa A, Senga T, Kikkawa F
    • Journal Title

      Cancer Sci 101(1)

      Pages: 143-8

    • NAID

      10027199881

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Enhanced cytotoxicity with a novel system combining the paclitaxel-2'-ethylcarbonate prodrug and an HSV amplicon with an attenuated replication-competent virus, HF10 as a helper virus.2009

    • Author(s)
      Ishida D, Nawa A, Tanino T, Goshima F, Luo CH, Iwaki M, Kajiyama H, Shibata K, Yamamoto E, Ino K, Tsurumi T, Nishiyama Y, Kikkawa F.
    • Journal Title

      Cancer Lett. 288

      Pages: 17-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592128
  • [Journal Article] The expression of dipeptidyl peptidase IV (DPPIV/CD26) is associated with enhanced chemosensitivity to paclitaxel in epithelial ovarian carcinoma cells2009

    • Author(s)
      Kajiyama H, Shibata K, Ino K, Mizutani S, Nawa A, Kikkawa F
    • Journal Title

      Cancer Sci 101(2)

      Pages: 347-54

    • NAID

      10026587626

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Enhanced cytotoxicity with a novel system combining the paclitaxel-2'-ethylcarbonate prodrug and an HSV amplicon with an attenuated replication-competent virus, HF10 as a helper virus2009

    • Author(s)
      Ishida D, Nawa A, Tanino T, Goshima F, Luo CH, Iwaki M, Kajiyama H, Shibata K, Yamamoto E, Ino K, Tsurumi T, Nishiyama Y, Kikkawa F
    • Journal Title

      Cancer Lett 288(1

      Pages: 17-27

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] N-acetylglucosaminyltransferase V regulatesextravillous trophoblast invasion through glycosylation of alpha5beta1 integrin2009

    • Author(s)
      Yamamoto E, Ino K, Miyoshi E, Inamori K, Abe A, Sumigama S, Iwase A, Kajiyama H, Shibata K, Nawa A, Kikkawa F
    • Journal Title

      Endocrinology 150(2)

      Pages: 990-9

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Role of the immunosuppressive enzyme indoleamine 2, 3-dioxygenase in the progression of ovarian carcinoma2009

    • Author(s)
      Inaba T, Ino K, Kajiyama H, Yamamoto E, Shibata K, Nawa A, Nagasaka T, Akimoto H, Takikawa O, Kikkawa F
    • Journal Title

      Gynecol Oncol 115(2)

      Pages: 185-92

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] High expression of N-acetylglucosaminyltransferase V in mucinous tumors of the ovary2009

    • Author(s)
      Takahashi N, Yamamoto E, Ino K, Miyoshi E, Nagasaka T, Kajiyama H, Shibata K, Nawa A, Kikkawa F
    • Journal Title

      Oncol Rep 22(5)

      Pages: 1027-32

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Inverse correlation between tumoral indoleamine 2, 3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival2008

    • Author(s)
      Ino K, Yamamoto E, Shibata K, Kajiyama H, Yoshida N, Terauchi M, Nawa A, Nagasaka T, Takikawa O, Kikkawa F
    • Journal Title

      Clin Cancer Res 14(8)

      Pages: 2310-7

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Gene directed enzyme prodrug therapy for ovarian cancer : Could GDEPT become a promising treatment against ovarian cancer2008

    • Author(s)
      Nawa A., Tanino T., Lou C., Iwaki M, Kajiyama H, Shibata K, Yamamoto E, Ino K, Nishiyama Y, Kikkawa F
    • Journal Title

      Anti-Cancer Agents Med Chem 8

      Pages: 232-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591930
  • [Journal Article] Non-engineered, naturally oncolytic herpes simplex virus HSVl HF-10 : applications for cancer gene therapy.2008

    • Author(s)
      Nawa A, Lou C, Zhang L, et al.
    • Journal Title

      Curr Gene Ther 8

      Pages: 208-210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591930
  • [Journal Article] Establishment and characterization of an ovarian yolk sac tumor cell line reveals possible involvement of Nkx2. 5 in tumor development2008

    • Author(s)
      Shibata K, Kajiyama H, Yamamoto E, Terauchi M, Ino K, Nawa A, Kikkawa F
    • Journal Title

      Oncology 74(1-2)

      Pages: 104-11

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Gene directed enzyme prodrug therapy for ovarian cancer: Could GDEPT become a promising treatment against ovarian cancer?2008

    • Author(s)
      Akihiro Nawa
    • Journal Title

      Anticancer Agents Med Chem 8

      Pages: 232-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591930
  • [Journal Article] Twist expression in patients with cervical cancer is associated with poor disease outcome2008

    • Author(s)
      Shibata K, Kajiyama H, Ino K, Terauchi M, Yamamoto E, Nawa A, Nomura S, Kikkawa F
    • Journal Title

      Ann Oncol 19(1)

      Pages: 81-5

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Involvement of SDF-1alpha/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma2008

    • Author(s)
      Kajiyama H, Shibata K, Terauchi M, Ino K, Nawa A, Kikkawa F
    • Journal Title

      Int J Cancer 122(1)

      Pages: 91-9

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Overexpression of indoleamine 2, 3-dioxygenase in human endometrial carcinoma cells induces rapid tumor growth in a mouse xenograft model2008

    • Author(s)
      Yoshida N, Ino K, Ishida Y, Kajiyama H, Yamamoto E, Shibata K, Terauchi M, Nawa A, Akimoto H, Takikawa O, Isobe K, Kikkawa F
    • Journal Title

      Clin Cancer Res 14(22)

      Pages: 7251-9

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer2008

    • Author(s)
      Tsukamoto H, Shibata K, Kajiyama H, Terauchi M, Nawa A, Kikkawa F
    • Journal Title

      BMC Cancer 19,8

      Pages: 74-74

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Gene directed enzyme prodrug therapy for ovarian cancer : could GDEPT become a promising treatment against ovarian cancer?2008

    • Author(s)
      Nawa A., Tanino T., Lou C, et al
    • Journal Title

      Anti-Cancer Agents Med Chem 8

      Pages: 232-239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591930
  • [Journal Article] Non-engineered, naturally oncolytic herpes simplex virus HSV1 HF10 : Applicationsfor cancer gene therapy2008

    • Author(s)
      Nawa A, Lou C, Zhang L, Ushijima Y, Ishida D, Kamakura M, Fujimoto Y, Goshima F, Kikkawa F, Nishiyama Y
    • Journal Title

      Curr Gene Ther 8

      Pages: 208-210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591930
  • [Journal Article] Taxol resistance among the different histological subtypes of ovarian cancer may be associated with the expression of class III beta-tubulin2008

    • Author(s)
      Umezu T, Shibata K, Kajiyama H, Terauchi M, Ino K, Nawa A, Kikkawa F
    • Journal Title

      Int J Gynecol Pathol 27(2)

      Pages: 207-12

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Involvement of SDF-lalpha/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma.2008

    • Author(s)
      Kajiyama H, Shibata K, Terauchi M, Ino K, Nawa A, Kikkawa F.
    • Journal Title

      Int J Cancer. 122(1)

      Pages: 91-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Inhibition of APN/CD13 leads to suppressed progressive potential in ovarian carcinoma cells2007

    • Author(s)
      Terauchi M, Kajiyama H, Shibata K, Ino K, Nawa A, Mizutani S, Kikkawa F
    • Journal Title

      BMC Cancer 27;7

      Pages: 140-140

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Carbon beam therapy in recurrent ovarian cancer.2007

    • Author(s)
      Akihiro Nawa
    • Journal Title

      Ann Oncol 19

      Pages: 192-194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591930
  • [Journal Article] Irradiation-induced epithelial-mesenchymal transition (EMT) related to invasive potential in endometrial carcinoma cells2007

    • Author(s)
      Tsukamoto H, Shibata K, Kajiyama H, Terauchi M, Nawa A, Kikkawa F
    • Journal Title

      Gynecol Oncol 107(3)

      Pages: 500-4

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Involvement of aminopeptidase N in enhanced chemosensitivity to paclitaxel in ovarian carcinoma in vitro and in vivo2007

    • Author(s)
      Yamashita M, Kajiyama H, Terauchi M, Shibata K, Ino K, Nawa A, Mizutani S, Kikkawa F
    • Journal Title

      Int J Cancer 120(10)

      Pages: 2243-50

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells.2007

    • Author(s)
      Kajiyama H, Shibata K, Terauchi M, Yamashita M, Ino K, Nawa A, Kikkawa F.
    • Journal Title

      Int J Oncol. 31(2)

      Pages: 277-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Possible involvement of TWIST in enhanced peritoneal metastasis of epithelial ovarian carcinoma2007

    • Author(s)
      Terauchi M, Kajiyama H, Yamashita M, Kato M, Tsukamoto H, Umezu T, Hosono S, Yamamoto E, Shibata K, Ino K, Nawa A, Nagasaka T, Kikkawa F
    • Journal Title

      Clin Exp Metastasis 24(5)

      Pages: 329-39

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Possible involvement of SDF-1alpha/CXCR4-DPPIV axis in TGF-beta1-induced enhancement of migratory potential in human peritoneal mesothelial cells2007

    • Author(s)
      Kajiyama H, Shibata K, Ino K, Nawa A, Mizutani S, Kikkawa F
    • Journal Title

      Cell Tissue Res 330(2)

      Pages: 221-9

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Uterine smooth muscle cells increase invasive ability of endometrial carcinoma cells through tumor-stromal interaction2007

    • Author(s)
      Tsukamoto H, Shibata K, Kajiyama H, Terauchi M, Nawa A, Kikkawa F
    • Journal Title

      Clin Exp Metastasis 24(6)

      Pages: 423-9

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients2007

    • Author(s)
      Hosono S, Kajiyama H, Terauchi M, Shibata K, Ino K, Nawa A, Kikkawa F
    • Journal Title

      Br J Cancer 96(2)

      Pages: 314-20

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Possible involvement of SDF-lalpha/CXCR4-DPPIV axis in TGF-betal-induced enhancement of migratory potential in human peritoneal mesothelial cells.2007

    • Author(s)
      Kajiyama H, Shibata K, Ino K, Nawa A, Mizutani S, Kikkawa F.
    • Journal Title

      Cell Tissue Res. 330(2)

      Pages: 221-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells2007

    • Author(s)
      Kajiyama H, Shibata K, Terauchi M, Yamashita M, Ino K, Nawa A, Kikkawa F
    • Journal Title

      nt J Oncol 31(2)

      Pages: 277-83

    • Data Source
      KAKENHI-PROJECT-19390427
  • [Journal Article] Retroviral vector backbone immunogenicity : identification of cytotoxic T-cell epitopes in retroviral vector-packaging sequences2005

    • Author(s)
      Kondo E, Akatsuka Y, Nawa A et al.
    • Journal Title

      Gene Therapy 12

      Pages: 252-258

    • Data Source
      KAKENHI-PROJECT-15591791
  • [Journal Article] Oncolytic viral therapy for human ovarian cancer using a novel replication-competent herpes simplex virus type I mutant in a mouse model.2003

    • Author(s)
      Akihiro Nawa
    • Journal Title

      Gynecol Oncol 91

      Pages: 81-8

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591791
  • [Journal Article] Oncolytic viral therapy for human ovarian cancer using a novel replication-competent herpes simplex virus type 1 mutant in a mouse model.2003

    • Author(s)
      Akihiro Nawa
    • Journal Title

      Gynecol Oncol 91

      Pages: 81-88

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591791
  • [Presentation] 葉酸修飾シクロデキストリンによるFOLR1陽性卵巣癌細胞の標的化2019

    • Author(s)
      斉藤伸一、小屋美博、梶山広明、山下守、吉川史隆、那波明宏
    • Organizer
      第71回日本産婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-19K09751
  • [Presentation] 腹膜播種巣における腹膜中皮細胞による浸潤フロンティア形成2018

    • Author(s)
      伊吉 祥平、梶山 広明、吉原 雅人、杉山 麻衣、小屋 美博、山北 由彦、那波 明宏、吉川 史隆
    • Organizer
      第17回 日本婦人科がん分子標的研究会
    • Data Source
      KAKENHI-PROJECT-16K15705
  • [Presentation] Notch経路を介したS1PレセプターのスイッチがEVTの浸潤を制御する2018

    • Author(s)
      三木 梨可、小谷 友美、澤田 雅子、小屋 美博、山下 守、伊藤 由美子、牛田 貴文、今井 健史、中野 知子、炭 誠二、吉川 史隆、那波 明宏
    • Organizer
      第70回 日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-16K15705
  • [Presentation] 卵巣癌腹膜播種巣における多様性の創出:癌関連腹膜中皮細胞とNotchシグナルの役割2018

    • Author(s)
      吉原 雅人、梶山 広明、杉山 麻衣、小屋 美博、山北 由彦、伊吉 祥平、那波 明宏、吉川 史隆
    • Organizer
      第17回 日本婦人科がん分子標的研究会
    • Data Source
      KAKENHI-PROJECT-16K15705
  • [Presentation] 表層上皮性卵巣癌におけるNotchシグナルを介した腹膜中皮細胞の役割2018

    • Author(s)
      杉山 麻衣、梶山 広明、吉原 雅人、小屋 美博、横井 暁、山下 守、那波 明宏、吉川 史隆
    • Organizer
      第70回 日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-16K15705
  • [Presentation] 卵巣癌においてCSPG4は細胞浸潤に大きく寄与している2018

    • Author(s)
      小屋 美博、吉原 雅人、梶山 広明、山下 守、吉川 史隆、那波 明宏
    • Organizer
      第70回 日本産科婦人科学会学術講演会
    • Data Source
      KAKENHI-PROJECT-16K15705
  • [Presentation] MITFは卵巣癌細胞において浸潤に寄与している2018

    • Author(s)
      小屋 美博、劉 文亭、杉山 麻衣、吉原 雅人、千賀 威、那波 明宏、吉川 史隆、梶山 広明
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K15705
  • [Presentation] 卵巣がん幹細胞と腹膜中皮細胞の相互作用2010

    • Author(s)
      松村寛子、柴田清住、梅津朋和、梶山広明、那波明宏、吉川史隆
    • Organizer
      第48回日本婦人科腫瘍学会、筑波
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2010-07-08
    • Data Source
      KAKENHI-PROJECT-22390311
  • [Presentation] 卵巣がん幹細胞と腹膜中皮細胞の相互作用2010

    • Author(s)
      松村寛子、柴田清住、梅津朋和、梶山広明、那波明宏、吉川史隆
    • Organizer
      第48回日本婦人科腫瘍学会
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2010-07-08
    • Data Source
      KAKENHI-PROJECT-21659383
  • [Presentation] 卵巣癌に対するウイルス療法2009

    • Author(s)
      那波明宏
    • Organizer
      日本癌治療学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-21592128
  • [Presentation] 変異型単純ヘルペスウイルス(HSV)を用いた卵巣癌に対する治療戦略2009

    • Author(s)
      那波明宏
    • Organizer
      日本産科婦人科学会(シンポジウム)
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2009-04-04
    • Data Source
      KAKENHI-PROJECT-21592128
  • [Presentation] Non-engineered, replication competent oncolytic herpes simplex virus HSV HF10 : Its unique pathogenity and Enhancement of cancer treatment in combination with an HSV amplicon system expressing granulocyte macrophage colony stimulation factor.2008

    • Author(s)
      那波明宏
    • Organizer
      ASGT
    • Place of Presentation
      BOSTON
    • Year and Date
      2008-05-30
    • Data Source
      KAKENHI-PROJECT-19591930
  • [Presentation] Non-Engineered, replication competent oncolytic herpes simplex virus HSV-1 HFIO : unique pathogenicity and enhancement of cancer treatment in combination with an HSV amplicon system expressing granulocyte-macrophage colony-stimulation factor (GM-CSF)2008

    • Author(s)
      NAWA Akihiro
    • Organizer
      第11回米国遺伝子治療学会
    • Year and Date
      2008-05-30
    • Data Source
      KAKENHI-PROJECT-19591930
  • [Presentation] 拡大するウイルス性感染症とその対策2008

    • Author(s)
      那波明宏
    • Organizer
      第49回日本臨床ウイルス学会シンポジゥム
    • Place of Presentation
      犬山
    • Year and Date
      2008-06-14
    • Data Source
      KAKENHI-PROJECT-19591930
  • 1.  KIKKAWA Fumitaka (40224985)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 36 results
  • 2.  NISHIYAMA Yukihiro (60115615)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  SHIBATA Kiyosumi (90335026)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 29 results
  • 4.  KAJIYAMA Hiroaki (00345886)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 30 results
  • 5.  KOIZUMI MASAE (60583028)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 6.  MUTO Yoshifumi
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  KOYA Yoshihiro
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 8.  NAKATSURA Tetsuya (30343354)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  YASUKAWA Masaki (60127917)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  Matsubara Keiichi (80263937)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Takashi Matsumoto (20346670)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  TSURUMI Tatsuya (90172072)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  水野 公雄 (40252241)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  井箟 一彦 (60303640)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  松原 裕子 (60403820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  Yamamoto Sawa
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  YAMAKITA Yoshihiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 18.  吉原 雅人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  西森 克彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  伊藤 昌文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  桧垣 実男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  鈴木 史朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi