Nawa Akihiro 那波明宏

… Alternative Names

Researcher Number	90242859
Affiliation (Current)	2019: 名古屋大学, 医学系研究科, 特任教授
Affiliation (based on the past Project Information) *help	2018 – 2019: 名古屋大学, 医学系研究科, 特任教授 2017: 名古屋大学, 医学(系)研究科(研究院), 特任教授 2016: 名古屋大学, 医学系研究科, 特任教授 2015: 名古屋大学, 医学(系)研究科(研究院), 教授 2015: 名古屋大学, 医学(系)研究科(研究院), 特任教授 … More
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator 腫瘍溶解性ウイルス / 卵巣癌 / HSVアンプリコン / 腫瘍溶解性ウイルス療法 / carrier cell / がん幹細胞 / ovarian cancer / 卵巣癌腹膜播種 / FOLR1 / 腫瘍溶解性ヘルペスウイルス … More Except Principal Investigator 卵巣癌 / 上皮間葉転換 / TGF-β / 腹膜播種 / 癌幹細胞 / CD133 / 上皮性卵巣癌 / 上皮間葉転換現象 / 転移浸潤 / 抗癌剤耐性 / 再発・再燃 / 耐性化 / 抗がん剤 / 転移 / paclitaxel / 上皮間葉転換(EMT) / TWIST / RNA-干渉 / 形態変化 / RNA-i / 薬剤耐性 / タキソール / 腹膜中皮細胞 / 幹細胞ニッチ / がん幹細胞 / α-SAM / ニッチ / CXCR4 / 腹膜中皮 / CXCR-4 / 免疫療法 / Glypican-3 / 卵巣がん幹細胞 / 卵巣明細胞腺癌 / ペプチドワクチン / 臨床試験 / glypican3 / 性分化 / 雌生殖器分化 / Lgr4 / 妊娠高血圧症候群 / 血管内皮 / 絨毛細胞 / 高血圧 / HMGA1 / トロホブラスト / マウス / 腫瘍発生学 / 子宮頸癌 / 動物モデル / トランスジェニックマウス Less

難治性再発卵巣腫瘍を標的とした改変型腫瘍溶解性ウイルスの開発Principal InvestigatorOngoing
- Principal Investigator
  
  那波明宏
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Nagoya University
Development of new strategic oncolytic virotherapy for advanced ovarian cancerPrincipal Investigator
- Principal Investigator
  
  那波明宏
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nagoya University
Role of HMGA1 on the pathogenesis of preeclampsia
- Principal Investigator
  
  Matsubara Keiichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Ehime University
Roles of growth factors and oncogenes on cervical carcinogenesis in transgenic mice
- Principal Investigator
  
  Takashi Matsumoto
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Ehime University
Establishment of polymer-equipped oncolytic virotherapeutics against ovarian cancer.Principal Investigator
- Principal Investigator
  
  NAWA Akihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nagoya University
  Ehime University
Analysis of Lgr4 function and development of anti-LGR4 antibody drug in gynecology
- Principal Investigator
  
  KOIZUMI MASAE
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Ehime University
Combination of stem cell research and immunotherapy in gynecologic cancer
- Principal Investigator
  
  KIKKAWA Fumitaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nagoya University
The development of the new cancer virus, cell therapy for ovarian cancer and the analysis of immune system responsePrincipal Investigator
- Principal Investigator
  
  NAWA Akihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Ehime University
  Nagoya University
Characteristic of gynecologic cancer stem cell and Epithelial-Mesenchymal Transition
- Principal Investigator
  
  KIKKAWA Fumitaka
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nagoya University
New strategy for the enhanced chemosensitivity and less metastatic potential of ovarian cancer targeting EMT inducible transcriptional factor
- Principal Investigator
  
  KIKKAWA Fumitaka
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nagoya University
Development of a novel oncolytic virotherapy for ovarian cancer and primary peritoneal serous carcinomaPrincipal Investigator
- Principal Investigator
  
  NAWA Akihiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nagoya University
The development of a novel genetherapy for pelitoneal dissemination of ovarian cancer using HSV-1 and its amplicon system.Principal Investigator
- Principal Investigator
  
  NAWA Akihiro
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nagoya University
  Aichi Cancer Center Research Institute
Oncolytic viral therapy for disseminated peritoneal ovarian cancer using a novel replication-competent herpes simplex virus type 1 mutant in mice.Principal Investigator
- Principal Investigator
  
  NAWA Akihiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Aichi Cancer Center
卵巣癌の浸潤促進に関与する接着分子を介した細胞内情報伝達機構の解析Principal Investigator
- Principal Investigator
  
  那波明宏
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nagoya University
婦人科癌でのリンパ節転移評価におけるHPV遺伝子検索の臨床的意義の解明Principal Investigator
- Principal Investigator
  
  那波明宏
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nagoya University

All 2018 2016 2015 2012 2011 2010 2009 2008 2007 2005 2003

All Journal Article Presentation

[Journal Article] Hematopoietic lineage cell-specific protein 1 (HS1), a hidden player in migration, invasion, and tumor formation, is over-expressed in ovarian carcinoma cells2018
- Author(s)
  Koya Yoshihiro, Liu Wenting, Yamakita Yoshihiko, Senga Takeshi, Shibata Kiyosumi, Yamashita Mamoru, Nawa Akihiro, Kikkawa Fumitaka, Kajiyama Hiroaki
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 32609-32623
- DOI
  10.18632/oncotarget.25975
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15705
[Journal Article] Clinical investigation of the safety and efficacy of a cervical intraepithelial neoplasia treatment using a hyperthermia device that uses heat induced by alternating magnetic fields.2016
- Author(s)
  Koji Koizumi, Toru Fujioka, Toshiaki Yasuoka, Aya Inoue, Yuka Uchikura, Hiroki Tanaka, Katsuko Takagi, Miki Mori, Masae Koizumi, Hisashi Hashimoto, Takashi Matsumoto, Yuko Matsubara, Keiichi Matsubara, Akihiro Nawa
- Journal Title
  
  Molecular and Clinical Oncology
  
  Volume: 13 Pages: 310-316
- DOI
  10.3892/mco.2016.929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462528
[Journal Article] Lgr4 controls specialization of female gonads in mice.2015
- Author(s)
  Koizumi, M. Oyama,K, Yamakami,Y, Kida,T, Satoh,R, Kato,S, Hidema,S, Oe,T, Goto,T, Clevers,H, Nawa,A, Nishimori,K
- Journal Title
  
  Biol Reprod.
  
  Volume: 93 Pages: 1-11
- DOI
  10.1095/biolreprod.114.123638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02442, KAKENHI-PROJECT-25462597
[Journal Article] Nitric oxide and reactive oxygen species in the pathogenesis of preeclampsia.2015
- Author(s)
  Inoue K, Asanuma T, Masuda K, Sakurai D, Higaki J, Nakatani S
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 308 Pages: 4600-16
- DOI
  10.3390/ijms16034600
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461112, KAKENHI-PROJECT-26462493, KAKENHI-PROJECT-25462597
[Journal Article] Spectrin αII and ssII tetramers contribute to platinum anticancer drug resistance in ovarian serous adenocarcinoma2012
- Author(s)
  Maeda O, Shibata K, Hosono S, Fujiwara S, Kajiyama H, Ino K, Nawa A, Tamakoshi K, Kikkawa F
- Journal Title
  
  Int J Cancer
  
  Volume: 130 Pages: 113-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592128
[Journal Article] Carrier cell-based delivery of replication-competent HSV-1 mutants enhances antitumor effect for ovarian cancer.2011
- Author(s)
  Fujiwara S, Nawa A, Luo CH, Kamakura M, Goshima F, Kondo C, Kiyono T, Kikkawa F, Nishiyama Y.
- Journal Title
  
  Cancer Gene Ther.
  
  Volume: 18 Pages: 77-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592128
[Journal Article] Establishment of cisplatin-resistant ovarian yolk sac tumor cells and investigation, of the mechanism of cisplatin resistance using this cell line2011
- Author(s)
  Shibata K, Umezu T, Sakurai M, Kajiyama H, Yamamoto E, Ino K, Nawa A, Kikkawa F
- Journal Title
  
  Gynecol Obstet Invest
  
  Volume: 71 Pages: 104-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592128
[Journal Article]2010
- Author(s)
  藤原多子、那波明宏、五島典、西山幸廣
- Journal Title
  
  Medical Bio(Ohmusha)
  
  Pages: 40-46
- Data Source
  KAKENHI-PROJECT-21592128
[Journal Article] Fertility-sparing surgery in young women with invasive epithelial ovarian cancer2010
- Author(s)
  Kajiyama H, Shibata K, Suzuki S, Ino K, Nawa A, Kawai M, Nagasaka T, Kikkawa F
- Journal Title
  
  Eur J Surg Oncol (in press)
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Identification and characterization of cancer stem cells in ovarian yolk sac tumors2010
- Author(s)
  Suzuki S, Terauchi M, Umezu T, Kajiyama H, Shibata K, Nawa A, Kikkawa F
- Journal Title
  
  Cancer Sci
  
  Volume: 101(10) Pages: 2179-85
- NAID
  10027832399
- Data Source
  KAKENHI-PROJECT-21659383
[Journal Article] Thyroid transcription factor 1 expression in ovarian carcinomas is an independent prognostic factor2010
- Author(s)
  Fujiwara S, Nawa A, Nakanishi T, Shimoyama Y, Kajiyama H, Shibata K, Ino K, Nakamura S, Kikkawa F, Yatabe Y
- Journal Title
  
  Hum Pathol (in press)
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Thyroid transcription factor 1 expression in ovarian carcinomas is an independent prognostic factor.2010
- Author(s)
  Fujiwara S, Nawa A, Nakanishi T, Shimoyama Y, Kajiyama H, Shibata K, Ino K, Nakamura S, Kikkawa F, Yatabe Y.
- Journal Title
  
  Hum Pathol. 41
  
  Pages: 560-565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592128
[Journal Article] Thyroid transcription factor 1 expression in ovarian carcinomas is an independent prognostic factor.2010
- Author(s)
  Fujiwara S, Nawa A, Nakanishi T, Shimoyama Y, Kajiyama H, Shibata K, Ino K, Nakamura S, Kikkawa F, Yatabe Y.
- Journal Title
  
  Hum Pathol.
  
  Volume: 41 Pages: 560-565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592128
[Journal Article] Gene silencing of glypican-3 in clear cell carcinoma of the ovary renders it more sensitive to the apoptotic agent paclitaxel in vitro and in vivo2010
- Author(s)
  Umezu T, Shibata K, Shimaoka M, Kajiyama H, Yamamoto E, Ino K, Nawa A, Senga T, Kikkawa F
- Journal Title
  
  Cancer Sci 101(1)
  
  Pages: 143-8
- NAID
  10027199881
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Enhanced cytotoxicity with a novel system combining the paclitaxel-2'-ethylcarbonate prodrug and an HSV amplicon with an attenuated replication-competent virus, HF10 as a helper virus.2009
- Author(s)
  Ishida D, Nawa A, Tanino T, Goshima F, Luo CH, Iwaki M, Kajiyama H, Shibata K, Yamamoto E, Ino K, Tsurumi T, Nishiyama Y, Kikkawa F.
- Journal Title
  
  Cancer Lett. 288
  
  Pages: 17-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592128
[Journal Article] The expression of dipeptidyl peptidase IV (DPPIV/CD26) is associated with enhanced chemosensitivity to paclitaxel in epithelial ovarian carcinoma cells2009
- Author(s)
  Kajiyama H, Shibata K, Ino K, Mizutani S, Nawa A, Kikkawa F
- Journal Title
  
  Cancer Sci 101(2)
  
  Pages: 347-54
- NAID
  10026587626
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Enhanced cytotoxicity with a novel system combining the paclitaxel-2'-ethylcarbonate prodrug and an HSV amplicon with an attenuated replication-competent virus, HF10 as a helper virus2009
- Author(s)
  Ishida D, Nawa A, Tanino T, Goshima F, Luo CH, Iwaki M, Kajiyama H, Shibata K, Yamamoto E, Ino K, Tsurumi T, Nishiyama Y, Kikkawa F
- Journal Title
  
  Cancer Lett 288(1
  
  Pages: 17-27
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] N-acetylglucosaminyltransferase V regulatesextravillous trophoblast invasion through glycosylation of alpha5beta1 integrin2009
- Author(s)
  Yamamoto E, Ino K, Miyoshi E, Inamori K, Abe A, Sumigama S, Iwase A, Kajiyama H, Shibata K, Nawa A, Kikkawa F
- Journal Title
  
  Endocrinology 150(2)
  
  Pages: 990-9
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Role of the immunosuppressive enzyme indoleamine 2, 3-dioxygenase in the progression of ovarian carcinoma2009
- Author(s)
  Inaba T, Ino K, Kajiyama H, Yamamoto E, Shibata K, Nawa A, Nagasaka T, Akimoto H, Takikawa O, Kikkawa F
- Journal Title
  
  Gynecol Oncol 115(2)
  
  Pages: 185-92
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] High expression of N-acetylglucosaminyltransferase V in mucinous tumors of the ovary2009
- Author(s)
  Takahashi N, Yamamoto E, Ino K, Miyoshi E, Nagasaka T, Kajiyama H, Shibata K, Nawa A, Kikkawa F
- Journal Title
  
  Oncol Rep 22(5)
  
  Pages: 1027-32
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Inverse correlation between tumoral indoleamine 2, 3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: its association with disease progression and survival2008
- Author(s)
  Ino K, Yamamoto E, Shibata K, Kajiyama H, Yoshida N, Terauchi M, Nawa A, Nagasaka T, Takikawa O, Kikkawa F
- Journal Title
  
  Clin Cancer Res 14(8)
  
  Pages: 2310-7
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Gene directed enzyme prodrug therapy for ovarian cancer : Could GDEPT become a promising treatment against ovarian cancer2008
- Author(s)
  Nawa A., Tanino T., Lou C., Iwaki M, Kajiyama H, Shibata K, Yamamoto E, Ino K, Nishiyama Y, Kikkawa F
- Journal Title
  
  Anti-Cancer Agents Med Chem 8
  
  Pages: 232-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591930
[Journal Article] Non-engineered, naturally oncolytic herpes simplex virus HSVl HF-10 : applications for cancer gene therapy.2008
- Author(s)
  Nawa A, Lou C, Zhang L, et al.
- Journal Title
  
  Curr Gene Ther 8
  
  Pages: 208-210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591930
[Journal Article] Establishment and characterization of an ovarian yolk sac tumor cell line reveals possible involvement of Nkx2. 5 in tumor development2008
- Author(s)
  Shibata K, Kajiyama H, Yamamoto E, Terauchi M, Ino K, Nawa A, Kikkawa F
- Journal Title
  
  Oncology 74(1-2)
  
  Pages: 104-11
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Gene directed enzyme prodrug therapy for ovarian cancer: Could GDEPT become a promising treatment against ovarian cancer?2008
- Author(s)
  Akihiro Nawa
- Journal Title
  
  Anticancer Agents Med Chem 8
  
  Pages: 232-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591930
[Journal Article] Twist expression in patients with cervical cancer is associated with poor disease outcome2008
- Author(s)
  Shibata K, Kajiyama H, Ino K, Terauchi M, Yamamoto E, Nawa A, Nomura S, Kikkawa F
- Journal Title
  
  Ann Oncol 19(1)
  
  Pages: 81-5
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Involvement of SDF-1alpha/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma2008
- Author(s)
  Kajiyama H, Shibata K, Terauchi M, Ino K, Nawa A, Kikkawa F
- Journal Title
  
  Int J Cancer 122(1)
  
  Pages: 91-9
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Overexpression of indoleamine 2, 3-dioxygenase in human endometrial carcinoma cells induces rapid tumor growth in a mouse xenograft model2008
- Author(s)
  Yoshida N, Ino K, Ishida Y, Kajiyama H, Yamamoto E, Shibata K, Terauchi M, Nawa A, Akimoto H, Takikawa O, Isobe K, Kikkawa F
- Journal Title
  
  Clin Cancer Res 14(22)
  
  Pages: 7251-9
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer2008
- Author(s)
  Tsukamoto H, Shibata K, Kajiyama H, Terauchi M, Nawa A, Kikkawa F
- Journal Title
  
  BMC Cancer 19,8
  
  Pages: 74-74
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Gene directed enzyme prodrug therapy for ovarian cancer : could GDEPT become a promising treatment against ovarian cancer?2008
- Author(s)
  Nawa A., Tanino T., Lou C, et al
- Journal Title
  
  Anti-Cancer Agents Med Chem 8
  
  Pages: 232-239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591930
[Journal Article] Non-engineered, naturally oncolytic herpes simplex virus HSV1 HF10 : Applicationsfor cancer gene therapy2008
- Author(s)
  Nawa A, Lou C, Zhang L, Ushijima Y, Ishida D, Kamakura M, Fujimoto Y, Goshima F, Kikkawa F, Nishiyama Y
- Journal Title
  
  Curr Gene Ther 8
  
  Pages: 208-210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591930
[Journal Article] Taxol resistance among the different histological subtypes of ovarian cancer may be associated with the expression of class III beta-tubulin2008
- Author(s)
  Umezu T, Shibata K, Kajiyama H, Terauchi M, Ino K, Nawa A, Kikkawa F
- Journal Title
  
  Int J Gynecol Pathol 27(2)
  
  Pages: 207-12
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Involvement of SDF-lalpha/CXCR4 axis in the enhanced peritoneal metastasis of epithelial ovarian carcinoma.2008
- Author(s)
  Kajiyama H, Shibata K, Terauchi M, Ino K, Nawa A, Kikkawa F.
- Journal Title
  
  Int J Cancer. 122(1)
  
  Pages: 91-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Inhibition of APN/CD13 leads to suppressed progressive potential in ovarian carcinoma cells2007
- Author(s)
  Terauchi M, Kajiyama H, Shibata K, Ino K, Nawa A, Mizutani S, Kikkawa F
- Journal Title
  
  BMC Cancer 27;7
  
  Pages: 140-140
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Carbon beam therapy in recurrent ovarian cancer.2007
- Author(s)
  Akihiro Nawa
- Journal Title
  
  Ann Oncol 19
  
  Pages: 192-194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591930
[Journal Article] Irradiation-induced epithelial-mesenchymal transition (EMT) related to invasive potential in endometrial carcinoma cells2007
- Author(s)
  Tsukamoto H, Shibata K, Kajiyama H, Terauchi M, Nawa A, Kikkawa F
- Journal Title
  
  Gynecol Oncol 107(3)
  
  Pages: 500-4
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Involvement of aminopeptidase N in enhanced chemosensitivity to paclitaxel in ovarian carcinoma in vitro and in vivo2007
- Author(s)
  Yamashita M, Kajiyama H, Terauchi M, Shibata K, Ino K, Nawa A, Mizutani S, Kikkawa F
- Journal Title
  
  Int J Cancer 120(10)
  
  Pages: 2243-50
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells.2007
- Author(s)
  Kajiyama H, Shibata K, Terauchi M, Yamashita M, Ino K, Nawa A, Kikkawa F.
- Journal Title
  
  Int J Oncol. 31(2)
  
  Pages: 277-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Possible involvement of TWIST in enhanced peritoneal metastasis of epithelial ovarian carcinoma2007
- Author(s)
  Terauchi M, Kajiyama H, Yamashita M, Kato M, Tsukamoto H, Umezu T, Hosono S, Yamamoto E, Shibata K, Ino K, Nawa A, Nagasaka T, Kikkawa F
- Journal Title
  
  Clin Exp Metastasis 24(5)
  
  Pages: 329-39
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Possible involvement of SDF-1alpha/CXCR4-DPPIV axis in TGF-beta1-induced enhancement of migratory potential in human peritoneal mesothelial cells2007
- Author(s)
  Kajiyama H, Shibata K, Ino K, Nawa A, Mizutani S, Kikkawa F
- Journal Title
  
  Cell Tissue Res 330(2)
  
  Pages: 221-9
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Uterine smooth muscle cells increase invasive ability of endometrial carcinoma cells through tumor-stromal interaction2007
- Author(s)
  Tsukamoto H, Shibata K, Kajiyama H, Terauchi M, Nawa A, Kikkawa F
- Journal Title
  
  Clin Exp Metastasis 24(6)
  
  Pages: 423-9
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients2007
- Author(s)
  Hosono S, Kajiyama H, Terauchi M, Shibata K, Ino K, Nawa A, Kikkawa F
- Journal Title
  
  Br J Cancer 96(2)
  
  Pages: 314-20
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Possible involvement of SDF-lalpha/CXCR4-DPPIV axis in TGF-betal-induced enhancement of migratory potential in human peritoneal mesothelial cells.2007
- Author(s)
  Kajiyama H, Shibata K, Ino K, Nawa A, Mizutani S, Kikkawa F.
- Journal Title
  
  Cell Tissue Res. 330(2)
  
  Pages: 221-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells2007
- Author(s)
  Kajiyama H, Shibata K, Terauchi M, Yamashita M, Ino K, Nawa A, Kikkawa F
- Journal Title
  
  nt J Oncol 31(2)
  
  Pages: 277-83
- Data Source
  KAKENHI-PROJECT-19390427
[Journal Article] Retroviral vector backbone immunogenicity : identification of cytotoxic T-cell epitopes in retroviral vector-packaging sequences2005
- Author(s)
  Kondo E, Akatsuka Y, Nawa A et al.
- Journal Title
  
  Gene Therapy 12
  
  Pages: 252-258
- Data Source
  KAKENHI-PROJECT-15591791
[Journal Article] Oncolytic viral therapy for human ovarian cancer using a novel replication-competent herpes simplex virus type I mutant in a mouse model.2003
- Author(s)
  Akihiro Nawa
- Journal Title
  
  Gynecol Oncol 91
  
  Pages: 81-8
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591791
[Journal Article] Oncolytic viral therapy for human ovarian cancer using a novel replication-competent herpes simplex virus type 1 mutant in a mouse model.2003
- Author(s)
  Akihiro Nawa
- Journal Title
  
  Gynecol Oncol 91
  
  Pages: 81-88
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591791
[Presentation] 腹膜播種巣における腹膜中皮細胞による浸潤フロンティア形成2018
- Author(s)
  伊吉祥平、梶山広明、吉原雅人、杉山麻衣、小屋美博、山北由彦、那波明宏、吉川史隆
- Organizer
  第17回日本婦人科がん分子標的研究会
- Data Source
  KAKENHI-PROJECT-16K15705
[Presentation] Notch経路を介したS1PレセプターのスイッチがEVTの浸潤を制御する2018
- Author(s)
  三木梨可、小谷友美、澤田雅子、小屋美博、山下守、伊藤由美子、牛田貴文、今井健史、中野知子、炭誠二、吉川史隆、那波明宏
- Organizer
  第70回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K15705
[Presentation] 卵巣癌腹膜播種巣における多様性の創出：癌関連腹膜中皮細胞とNotchシグナルの役割2018
- Author(s)
  吉原雅人、梶山広明、杉山麻衣、小屋美博、山北由彦、伊吉祥平、那波明宏、吉川史隆
- Organizer
  第17回日本婦人科がん分子標的研究会
- Data Source
  KAKENHI-PROJECT-16K15705
[Presentation] 表層上皮性卵巣癌におけるNotchシグナルを介した腹膜中皮細胞の役割2018
- Author(s)
  杉山麻衣、梶山広明、吉原雅人、小屋美博、横井暁、山下守、那波明宏、吉川史隆
- Organizer
  第70回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K15705
[Presentation] 卵巣癌においてCSPG4は細胞浸潤に大きく寄与している2018
- Author(s)
  小屋美博、吉原雅人、梶山広明、山下守、吉川史隆、那波明宏
- Organizer
  第70回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K15705
[Presentation] MITFは卵巣癌細胞において浸潤に寄与している2018
- Author(s)
  小屋美博、劉文亭、杉山麻衣、吉原雅人、千賀威、那波明宏、吉川史隆、梶山広明
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15705
[Presentation] 卵巣がん幹細胞と腹膜中皮細胞の相互作用2010
- Author(s)
  松村寛子、柴田清住、梅津朋和、梶山広明、那波明宏、吉川史隆
- Organizer
  第48回日本婦人科腫瘍学会、筑波
- Place of Presentation
  つくば国際会議場
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-22390311
[Presentation] 卵巣がん幹細胞と腹膜中皮細胞の相互作用2010
- Author(s)
  松村寛子、柴田清住、梅津朋和、梶山広明、那波明宏、吉川史隆
- Organizer
  第48回日本婦人科腫瘍学会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21659383
[Presentation] 卵巣癌に対するウイルス療法2009
- Author(s)
  那波明宏
- Organizer
  日本癌治療学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21592128
[Presentation] 変異型単純ヘルペスウイルス(HSV)を用いた卵巣癌に対する治療戦略2009
- Author(s)
  那波明宏
- Organizer
  日本産科婦人科学会(シンポジウム)
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-04-04
- Data Source
  KAKENHI-PROJECT-21592128
[Presentation] Non-engineered, replication competent oncolytic herpes simplex virus HSV HF10 : Its unique pathogenity and Enhancement of cancer treatment in combination with an HSV amplicon system expressing granulocyte macrophage colony stimulation factor.2008
- Author(s)
  那波明宏
- Organizer
  ASGT
- Place of Presentation
  BOSTON
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-19591930
[Presentation] Non-Engineered, replication competent oncolytic herpes simplex virus HSV-1 HFIO : unique pathogenicity and enhancement of cancer treatment in combination with an HSV amplicon system expressing granulocyte-macrophage colony-stimulation factor (GM-CSF)2008
- Author(s)
  NAWA Akihiro
- Organizer
  第11回米国遺伝子治療学会
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-19591930
[Presentation] 拡大するウイルス性感染症とその対策2008
- Author(s)
  那波明宏
- Organizer
  第49回日本臨床ウイルス学会シンポジゥム
- Place of Presentation
  犬山
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-19591930

1. KIKKAWA Fumitaka (40224985)

# of Collaborated Projects: 4 results

# of Collaborated Products: 35 results
2. NISHIYAMA Yukihiro (60115615)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. SHIBATA Kiyosumi (90335026)

# of Collaborated Projects: 3 results

# of Collaborated Products: 29 results
4. KAJIYAMA Hiroaki (00345886)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
5. KOIZUMI MASAE (60583028)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. NAKATSURA Tetsuya (30343354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YASUKAWA Masaki (60127917)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Matsubara Keiichi (80263937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. Takashi Matsumoto (20346670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. TSURUMI Tatsuya (90172072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 水野公雄 (40252241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 井箟一彦 (60303640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 松原裕子 (60403820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MUTO Yoshifumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KOYA Yoshihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Yamamoto Sawa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 西森克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 桧垣実男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nawa Akihiro 那波 明宏

NAWA Akihiro 那波 明宏

那波 明宏 ナワ アキヒロ

Research Projects

Research Products

Co-Researchers

難治性再発卵巣腫瘍を標的とした改変型腫瘍溶解性ウイルスの開発Principal InvestigatorOngoing

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Development of new strategic oncolytic virotherapy for advanced ovarian cancerPrincipal Investigator

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Role of HMGA1 on the pathogenesis of preeclampsia

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Roles of growth factors and oncogenes on cervical carcinogenesis in transgenic mice

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Establishment of polymer-equipped oncolytic virotherapeutics against ovarian cancer.Principal Investigator

Principal Investigator

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Analysis of Lgr4 function and development of anti-LGR4 antibody drug in gynecology

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Combination of stem cell research and immunotherapy in gynecologic cancer

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The development of the new cancer virus, cell therapy for ovarian cancer and the analysis of immune system responsePrincipal Investigator

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Characteristic of gynecologic cancer stem cell and Epithelial-Mesenchymal Transition

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New strategy for the enhanced chemosensitivity and less metastatic potential of ovarian cancer targeting EMT inducible transcriptional factor

Principal Investigator

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Development of a novel oncolytic virotherapy for ovarian cancer and primary peritoneal serous carcinomaPrincipal Investigator

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The development of a novel genetherapy for pelitoneal dissemination of ovarian cancer using HSV-1 and its amplicon system.Principal Investigator

Principal Investigator

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Oncolytic viral therapy for disseminated peritoneal ovarian cancer using a novel replication-competent herpes simplex virus type 1 mutant in mice.Principal Investigator

Principal Investigator

Nawa Akihiro 那波明宏

NAWA Akihiro 那波明宏

那波明宏ナワアキヒロ