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YAGINUMA Yuji
柳沼 裕二
…
Alternative Names
柳沼 裕二 ヤギヌマ ユウジ
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Researcher Number
90250571
Other IDs
https://orcid.org/0000-0002-3293-3484
Affiliation (based on the past Project Information)
*help
2019 – 2023: 熊本大学, 大学院生命科学研究部(保), 教授
2008 – 2009: 旭川医科大学, 医学部, 准教授
1993 – 1999: 旭川医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology
Except Principal Investigator
Obstetrics and gynecology
/
Basic Section 48030:Pharmacology-related
/
Experimental pathology
Keywords
Principal Investigator
卵巣癌 / 癌抑制遺伝子 / HPV / テロメラーゼ / 子宮頚癌 / Rb / P16 / P15 / IGF-II / 子宮体癌
…
More
/ 細胞診 / 遺伝子治療 / 細胞株 / 点突然変異 / 絨毛癌 / 子宮癌 / p53遺伝子 / 発癌 / 婦人科腫瘍 / SSCP / LOH / 癌遺伝子
…
More
Except Principal Investigator
IGF-II / 卵巣癌 / 子宮体癌 / 子宮頚癌 / 食道扁平上皮癌 / 免疫組織化学染色法 / 遺伝子発現量 / トランスフェリン受容体 / 分子標的治療薬 / 食道癌 / PTEN / p16 / p15 / cancer / ovary / uterine / Rb / P16 / P15 / 発癌 / Differential Display法 / 癌抑制遺伝子 / 癌遺伝子 / Ovarian carcinoma / Endometrial carcinoma / Cervical carcinoma / Insulin-like growth factor 2 (IGF2) / Imprinting / 弛緩現象 / 刷り込み遺伝子 / IGF2 / 遺伝子刷り込み現象 / ラパマイシン / HIF-1 / ラバマイシン / マウス / 肝発癌 / 蛋白翻訳 / 蛋白合成 / 肝癌 / IRES
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Research Projects
(
9
results)
Research Products
(
10
results)
Co-Researchers
(
7
People)
Project Start Year (Newest)
Project Start Year (Oldest)
食道癌におけるトランスフェリン受容体の機能解明と分子標的薬の探索
Principal Investigator
山本 裕之
Project Period (FY)
2019 – 2024
Research Category
Grant-in-Aid for Scientific Research (C)
Review Section
Basic Section 48030:Pharmacology-related
Research Institution
Junshin Gakuen University
Mechanism of rapamycin-resistant translation in mouse hepatocellular carcinoma cells
Principal Investigator
OGAWA Katsuhiro
Project Period (FY)
2008 – 2010
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Experimental pathology
Research Institution
Asahikawa Medical College
細胞老化,不死化に関与する遺伝子の探索
Principal Investigator
Principal Investigator
柳沼 裕二
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field
Obstetrics and gynecology
Research Institution
Asahikawa Medical College
Molecular cloning of candidate gene for human ovarian carcinogenesis
Principal Investigator
ISHIKAWA Mutsuo
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
ASAHIKAWA MEDICAL COLLEGE
婦人科腫瘍におけるテロメラーゼ活性の意義に関する研究
Principal Investigator
Principal Investigator
柳沼 裕二
Project Period (FY)
1996
Research Category
Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field
Obstetrics and gynecology
Research Institution
Asahikawa Medical College
Relaxation of IGF2 Imprinting in Human Gynecologic Tumors
Principal Investigator
YOSHIDA Toshiaki
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Obstetrics and gynecology
Research Institution
Asahikawa medical college
卵巣腫瘍の遺伝子治療に関する基礎的検討
Principal Investigator
Principal Investigator
柳沼 裕二
Project Period (FY)
1995
Research Category
Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field
Obstetrics and gynecology
Research Institution
Asahikawa Medical College
婦人科腫瘍の発生メカニズムの分子生物的解析
Principal Investigator
Principal Investigator
柳沼 裕二
Project Period (FY)
1994
Research Category
Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field
Obstetrics and gynecology
Research Institution
Asahikawa Medical College
婦人科腫瘍の発癌過程における癌抑制遺伝子の不活性化メカニズムに関する検討
Principal Investigator
Principal Investigator
柳沼 裕二
Project Period (FY)
1993
Research Category
Grant-in-Aid for Encouragement of Young Scientists (A)
Research Field
Obstetrics and gynecology
Research Institution
Asahikawa Medical College
All
2009
2008
2007
2006
2005
All
Journal Article
Presentation
[Journal Article] Hypoxia-independent overexpression of hypoxia-inducible factor 1α as an early change in mouse hepatocarcinognesis.
2006
Author(s)
Tanaka H, Yamamoto M, Hashimoto N, Miyakoshi M, Tamakawa S, Yoshie M, Tokusashi Y, Yokoyama K, Yaginuma Y, Ogawa K.
Journal Title
Cancer Res 66
Pages
: 11263-11270
Data Source
KAKENHI-PROJECT-20590392
[Presentation] Rapamycin induces necrosis in mouse hepatocellular carcinomas by antiangiogenic activity, but also activates cap-independent translation of HIF-1α in hepatocellular carcinoma cells.
2009
Author(s)
Tanaka H,, Yamamoto M, Hashimoto N, Miyakoshi M, Tamakawa S, Yoshie M, Tokusashi Y, Yokoyama K, Yaginuma Y, Ogawa K.
Organizer
American Association for Cancer Research Annual Meeting
Place of Presentation
Denver, CO
Data Source
KAKENHI-PROJECT-20590392
[Presentation] Rapamycin activates cap-independent translation of HIF-1α in hepatocellular carcinoma cells.
2009
Author(s)
Tanaka H, Yamamoto M, Miyakoshi M, Tamakawa S, Yaginuma Y, Ogawa K.
Organizer
日本癌学会
Data Source
KAKENHI-PROJECT-20590392
[Presentation] Rapamycin処理マウス肝癌細胞におけるIRES依存的HIF-1α蛋白翻訳の活性化
2008
Author(s)
田中宏樹、山本雅大、宮腰昌明、玉川進、吉江真澄、徳差良彦、柳沼裕二、小川勝洋
Organizer
分子生物学会
Data Source
KAKENHI-PROJECT-20590392
[Presentation] HPVI8型E7蛋白とセントロメア蛋白の結合領域の同定とその機能解析
2008
Author(s)
柳沼裕二
Organizer
第97回日本病理学会総会
Place of Presentation
もてなしドーム地下広場(石川県金沢市)
Year and Date
2008-05-16
Data Source
KAKENHI-PROJECT-20590392
[Presentation] Functional interaction between human papillomavirus type 18 E7 protein and centromere protein that is essentrial for chromosome segregation
2008
Author(s)
柳沼裕二
Organizer
AACR年次会合2008
Place of Presentation
サンディエゴコンベンションセンター(カリフォルニア州サンディエゴ)
Year and Date
2008-04-12
Data Source
KAKENHI-PROJECT-20590392
[Presentation] Angiotoxic effect of rapamycin in mouse HCC cells and rapamycin-resistant mechanism of HCC cells.
2008
Author(s)
Tanaka H, Yamamoto M, Miyakoshi M, Tamakawa S, Yoshie M, Tokusashi Y, Yaginuma Y, Ogawa K.
Organizer
日本癌学会
Data Source
KAKENHI-PROJECT-20590392
[Presentation] Reciprocal activation of PI3K/Akt signaling and HIF-1α in progression of mouse hepatocarcinogenesis.
2007
Author(s)
Tanaka H, Yamamoto M, Hashimoto N, Miyakoshi M, Tamakawa S, Yoshie M, Tokusashi Y, Yokoyama K, Yaginuma Y, Ogawa K.
Organizer
American Association for Cancer Research Annual Meeting
Place of Presentation
Los Angeles, CA
Data Source
KAKENHI-PROJECT-20590392
[Presentation] Hypoxia-independent overexpression of hypoxia-inducible factor 1α as an early change in mouse hepatocarcinogenesis.
2006
Author(s)
Tanaka H, Yamamoto M, Hashimoto N, Miyakoshi M, Tamakawa S, Yoshie M, Tokusashi Y, Yokoyama K, Yaginuma Y, Ogawa K.
Organizer
American Association for Cancer Research Annual Meeting
Place of Presentation
Washington DC
Data Source
KAKENHI-PROJECT-20590392
[Presentation] Expression of hypoxia-inducible factor 1α in the early step of hepatic carcinogenesis.
2005
Author(s)
Tanaka H, Yamamoto M, Hashimoto N, Miyakoshi M, Tamakawa S, Yoshie M, Tokusashi Y, Yokoyama K, Yaginuma Y, Ogawa K.
Organizer
American Association for Cancer Research Annual Meeting
Place of Presentation
Anaheim, CA
Data Source
KAKENHI-PROJECT-20590392
# of Projects (Dsc)
# of Projects (Asc)
1.
OGAWA Katsuhiro
(50045514)
# of Collaborated Projects:
1 results
# of Collaborated Products:
8 results
2.
YOSHIDA Toshiaki
(80271782)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
3.
ISHIKAWA Mutsuo
(20002131)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
4.
HAYASHI Hiroaki
(20164957)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
5.
玉川 進
(70188415)
# of Collaborated Projects:
1 results
# of Collaborated Products:
1 results
6.
山本 雅大
(30431399)
# of Collaborated Projects:
1 results
# of Collaborated Products:
8 results
7.
山本 裕之
(10466295)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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