SHIMOTAKE Takashi 下竹孝志

Researcher Number	90254341
External Links
Affiliation (based on the past Project Information) *help	2003 – 2005: KYOTO PREFECTURAL UNIVERSITY OF MEDICINE, CHILDREN RESEARCH HOSPITAL, DIVISION OF SURGERY, ASSISTANT, 医学研究科, 助手 1994 – 2002: 京都府立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Pediatric surgery / 小児外科 Except Principal Investigator 小児外科 / Pediatric surgery / Pediatric surgery
Keywords	Principal Investigator 消化管神経叢 / 神経堤細胞 / ヒルシュスプルング病 / PELVIC FLOOR MUSCLE / 骨盤底筋群 / ENTERIC NERVOUS SYSTEM / NEURAL CREST CELL / HIRSCHSPRUNG DISEASE / 分化誘導 / 発生学 … More / ヒルシュスプリング病 / 神経提細胞 / EMBRYOGENESIS / DEVELOPMENT / ANORECTAL MALFORMATIONS / 発生 / 筋細胞 / 骨盤底 / 再生 / 神経筋接合 / 直腸肛門奇形 / gene expression / somite / embryology / gut anomaly / 消化管 / 先天性奇形 / 体軸 / 遣伝子 / 遺伝子 / 体節 / 胎生学 / 消化管奇形 / MEN syndrome / hypoganglionosis / RET gene / Hirschsprung / 分子遺伝学 / RET遺伝子 / 臨床遺伝学 / アポトーシス / ABR / 聴覚反応 / 神経発生 … More Except Principal Investigator Shh / 胎生学 / 直腸肛門奇形 / 形態学 / Morphology / Receptor / Embryology / Anorectal malformations / tethered cord syndrome / シグナル伝達系 / レセプター / 発生学 / PELVIC FLOOR MUSCLE / NEURAL DEVELOPMENT / RETINOIC ACID / ANORECTAL MALFORMATION / 骨盤底筋 / 神経発生 / レチノイン酸 / maturation / enteric ganglia / neural cell / Hirschsprung / 神経栄養因子 / ヒルシュスプリング病類縁疾患 / 消化管神経叢 / 分化誘導 / 消化管神経業 / 神経堤細胞 / ヒルシュスプルング病 / 胆道 / 胆道閉鎖症 / アポトーシス / 胆迫閉鎖症 Less

Dynamic analysis of Shh and specific receptor in embryologic process of anorectal malformations.
- Principal Investigator
  
  IWAI Naomi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatric surgery
- Research Institution
  Kyoto Prefectural University of Mdicine
DEVELOPMENTAL STUDY OF PELVIC FLOOR MUSCLES IN ANORECTAL MALFORMATIONSPrincipal Investigator
- Principal Investigator
  
  SHIMOTAKE Takashi
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatric surgery
- Research Institution
  KYOTO PREFECTURAL UNIVERSITY OF MEDICINE
DEVELOPMENTAL STUDY OF ENTERIC NERVOUS SYSTEM BY NEURAL CREST CELLS FOR CONGENITAL AGANGLIONOSISPrincipal Investigator
- Principal Investigator
  
  SHIMOTAKE Takashi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Kyoto Prefectural University of Medicine
EMBRYOLOGICAL STUDY OF RETINOIC ACID RECEPTORS IN ANIMAL MODEL FOR ANORECTAL MALFORMATION
- Principal Investigator
  
  IWAI Naomi
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatric surgery
- Research Institution
  KYOTO PREFECTURAL UNIVERSITY OF MEDICINE
Embryological study of gastrointestinal tract in pediatric surgical diseasesPrincipal Investigator
- Principal Investigator
  
  SHIMOTAKE Takashi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Kyoto Prefectural University of Medicine
胆道閉鎖症の胆管変性におけるアポトーシスの関与とその治療法の確立に関する基礎研究
- Principal Investigator
  
  YANAGIHARA Jun
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  小児外科
- Research Institution
  Kyoto Prefectural University of Medicine
Mutational analysis of Hirschsprung's disease and its related disorders.Principal Investigator
- Principal Investigator
  
  SHIMOTAKE Takashi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  小児外科
- Research Institution
  Kyoto Prefectural University of Medicine
消化管壁内神経叢の病態発生における神経堤細胞の増殖と自然死に関する形態学的研究Principal Investigator
- Principal Investigator
  
  下竹孝志
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  小児外科
- Research Institution
  Kyoto Prefectural University of Medicine
Maturation therapy of enteric ganglia for pseudo-Hirschsprung's disease.
- Principal Investigator
  
  IWAI Naomi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  小児外科
- Research Institution
  Kyoto prefectural University of Medicine
ヒルシュスプルング病及び同類縁疾患の全身病変に関する胎生学的研究Principal Investigator
- Principal Investigator
  
  下竹孝志
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  小児外科
- Research Institution
  Kyoto Prefectural University of Medicine

All 2006 2005 2004 Other

All Journal Article Book

[Book] Anorectal malformations in children2006
- Author(s)
  IwaiN, Deguchi E, Shimotake T, Kimura O
- Publisher
  Springer, Heidelberg, Germany
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390534
[Book] Anorectal malformations in children2006
- Author(s)
  Iwai N, Deguchi E, Shimotake T, Kimura O
- Publisher
  Springer, Heidelherg, Germany
- Data Source
  KAKENHI-PROJECT-15390534
[Book] Postoperative electromanometrical, myographical and imaging evaluations. Anorectmations in children(AM Holschneider ed)2006
- Author(s)
  Iwai N, Deguchi E, Shimotake T, Kimura O
- Publisher
  Springer(In press)
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Infrared spectrophotometry of intraluminal meconiumcalculi in a neonate with imperforate anus and rectal fistula2006
- Author(s)
  Shimotake T, Higuchi K, Tsuda T, Aoi S, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery 41-6
  
  Pages: 1173-1176
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Morphology of the enteric nervous system in the hindgut of an infant with cloacal extrophy2006
- Author(s)
  Shimotake T, Tsuda T, Aoi S, Tomiyama H, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery 41-12
  
  Pages: 1957-1961
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Infrared spectrophotometry of intraluminal meconium calculi in a neonate with imperforate anus and rectal fistula2006
- Author(s)
  Shimotake T, Higuchi K, Tsuda T, Aoi S, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery 41・6
  
  Pages: 1173-1176
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Morphology of the enteric nervous system in the hindgut of an infant with cloacal extrophy2006
- Author(s)
  Shimotake T, TsudaT, Aoi S, Tomiyama H, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery 41・12
  
  Pages: 1957-1961
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Infrared spectrophotometry of intraluminal meconiumcalculi in a neonate with imperforate anus and rectal fistula2006
- Author(s)
  Shimotake T, HiguchiK, TsudaT, Aoi S, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery 41・6
  
  Pages: 1173-1176
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Morphology of the enteric nervous system in the hindgut of an infant with cloacal extrophy2006
- Author(s)
  Shimotake T, Tsuda T, Aoi S, Tomiyama H, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery 41・12
  
  Pages: 1957-1961
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Postoperative electromanometric, myographic, and anal endosonographic evaluations2006
- Author(s)
  Iwai N, Deguchi E, Shimotake T, Kimura 0
- Journal Title
  
  Anorectal malformations in children, Springer, Heidelberg, Germany
  
  Pages: 345-349
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Impaired expression of myogenic regulatory molecules in the pelvic floor muscles of murine embryos with anorectal malformations2005
- Author(s)
  Aoi S, Shimotake T, Tsuda T, Deguchi E, Iwai N
- Journal Title
  
  J Pediatr Surg (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Neuricutaneus melanosis associated with Hirschsprung's disease in a male neonate2005
- Author(s)
  Iwabuchi T, Shimotake T, Furukawa T, Tsuda T, Aoi S, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery 40(8)
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] ^<123>I-MIBG radio-guided navigation surgery for recurrent medullary thyroid carcinoma in a girl with multiple endocrine neoplasia type 2B.2005
- Author(s)
  Shimotake T, Aoi S, Fumino S, Iwai N
- Journal Title
  
  J Pediatr Surg (in press)
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Respiratory insufficiency in a newborn with mesenchymal hamartoma of the chest wall2005
- Author(s)
  Shimotake T, Fumino S, Aoi S, Tsuda T, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery 40(4)
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Impaired expression of myogenic regulatory molecules in the pelvic floor muscles of murine embryos with anorectal malformations.2005
- Author(s)
  Aoi S, Shimotake T, Tsuda T, Deguchi E, Iwai N
- Journal Title
  
  J Pediatr Surg (in press)
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Infrared spectrophotometry of intraluminal meconium calculi in a neonate with imperforate anus and rectourethral fistula2005
- Author(s)
  Shimotake T, Higuchi, K, Tsuda T, Aoi S, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery (in press)
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Intestinal malrotation with midgut volvulus in a 10-year-old girl.2005
- Author(s)
  Kume Y, Fumino S, Shimotake T, Iwai N
- Journal Title
  
  J Pediatr Surg (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Neurocutaneous melanosis associated with Hirschsprung's disease in a male neonate2005
- Author(s)
  Iwabuchi T, Shimotake T, Furukawa T, Tsuda T, Aoi S, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery (in press)
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Neurocutaneous melanosis associated with Hirschsprung's disease in a male neonate.2005
- Author(s)
  Iwabuchi T, Shimotake T, Furukawa T, Tsuda T, Aoi S, Iwai N
- Journal Title
  
  J Pediatr Surg (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Morphology of the Enteric Nervous System in the Hindgut of an Infant With Cloacal Exstrophy : A Preliminary Report.2005
- Author(s)
  Shimotake T, Tsuda T, Aoi S, Tomiyama H, Iwai N
- Journal Title
  
  Eur J Pediatr Surg (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Developmental study of the tethered spinal cord in murine embryos with anorectal malformations2005
- Author(s)
  Tsuda T, Shimotake T, Aoi S, Kume Y, Deguchi E, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery 40(12)
  
  Pages: 1927-1930
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Impaired expression of myogenic regulatory molecules in the pelvic floor muscles of murine embryos with anorectal malformations2005
- Author(s)
  Aoi S, Shimotake T, Tsuda T, Deguchi E, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery (in press)
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Morphology of the enteric nervous system in the hindgut of an infant with cloacal exstrophy2005
- Author(s)
  Shimotake T, Tsuda T, Aoi S, Tomiyama H, Iwai N
- Journal Title
  
  European Journal of Pediatric Surgery (in press)
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Mucoepidermal carcinoma of the lung detected by positron emission tomography in a 5-year-old girl.2005
- Author(s)
  Kinoshita H, Shimotake T, Furukawa T, Deguchi B, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery (in press)
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] ^<123>I-MIBG radio-guided navigation surgery for recurrent medullary thyroid carcinoma in a girl with multiple endocrine neoplasia type 2B2005
- Author(s)
  Shimotake T, Aoi S, Fumino S, Iwai N
- Journal Title
  
  J Pediatr Surg (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Infrared spectrophotometry of intraluminal meconium calculi in a neonate with imperforate anus and rectourethral fistula.2005
- Author(s)
  Shimotake T, Tsuda T, Aoi S, Kohji Higuchi, Iwai N
- Journal Title
  
  J Pediatr Surg (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Impaired expression of myogenic regulatory molecules in the pelvic floor muscles of murine embryos with anorectal malformations.2005
- Author(s)
  Aoi S, Shimotake T, Tsuda T, Deguchi E, Iwai N
- Journal Title
  
  Journal of Pediatric Surgery 40(5)
  
  Pages: 805-809
- Data Source
  KAKENHI-PROJECT-15390534
[Journal Article] Intestinal malrotation with midgut volvulus in a 10-year-old girl..2004
- Author(s)
  Kume Y, Fumino S, Shimotake T, Iwai N
- Journal Title
  
  J Pediatr Surg 39
  
  Pages: 783-784
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Infrared spectrophotometry of intraluminal meconium calculi in a neonate with imperforate anus and rectourethral fistula
- Author(s)
  Shimotake T, Tsuda T, Aoi S, Kohji Higuchi, Iwai N.
- Journal Title
  
  J Pediatr Surg (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Impaired expression of myogenic regulatory molecules in the pelvic floor muscles of murine embryos with anorectal malformations.
- Author(s)
  Aoi S, Shimotake T, Tsuda T, Deguchi E, Iwai N
- Journal Title
  
  J Pediatr Surg (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Mucoepidermal carcinoma of the lung detected by positron emission tomography in a 5-year-old girl
- Author(s)
  Kinoshita H, Shimotake T, Furukawa T, Deguchi E, Iwai N
- Journal Title
  
  J Pediatr Surg (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Morphology of the Enteric Nervous System in the Hindgut of an Infant With Cloacal Exstrophy : A Preliminary Report..
- Author(s)
  Shimotake T, Tsuda T, Aoi S, Kohji Higuchi, Iwai N.
- Journal Title
  
  Euro J Pediatr Surg (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] ^<123>I-MIBG radio-guided navigation surgery for recurrent medullary thyroid carcinoma in a girl with multiple endocrine neoplasia type 2B...
- Author(s)
  Shimotake T, Aoi S, Fumino S, Iwai N
- Journal Title
  
  J Pediatr Surg (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Respiratory insufficiency in a newborn patient with mesenchymal hamartoma of the chest wall occupying the thoracic cavity
- Author(s)
  Shimotake T, Fumino S, Aoi S, Tsuda T, Iwai N
- Journal Title
  
  J Pediatr Surg (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557146
[Journal Article] Neurocutaneous melanosis associated with Hirschsprung's disease in a male neonate..
- Author(s)
  Iwabuchi T, Shimotake T, Furukawa T, Tsuda T, Aoi S, Iwai N
- Journal Title
  
  J Pediatr Surg (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557146

1. IWAI Naomi (90128695)

# of Collaborated Projects: 4 results

# of Collaborated Products: 35 results
2. YANAGIHARA Jun (30158026)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KIMURA Osamu (10315963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

SHIMOTAKE Takashi 下竹 孝志

Research Projects

Research Products

Co-Researchers

Dynamic analysis of Shh and specific receptor in embryologic process of anorectal malformations.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DEVELOPMENTAL STUDY OF PELVIC FLOOR MUSCLES IN ANORECTAL MALFORMATIONSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DEVELOPMENTAL STUDY OF ENTERIC NERVOUS SYSTEM BY NEURAL CREST CELLS FOR CONGENITAL AGANGLIONOSISPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

EMBRYOLOGICAL STUDY OF RETINOIC ACID RECEPTORS IN ANIMAL MODEL FOR ANORECTAL MALFORMATION

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Embryological study of gastrointestinal tract in pediatric surgical diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

胆道閉鎖症の胆管変性におけるアポトーシスの関与とその治療法の確立に関する基礎研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mutational analysis of Hirschsprung's disease and its related disorders.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

消化管壁内神経叢の病態発生における神経堤細胞の増殖と自然死に関する形態学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Maturation therapy of enteric ganglia for pseudo-Hirschsprung's disease.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒルシュスプルング病及び同類縁疾患の全身病変に関する胎生学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Anorectal malformations in children2006

Author(s)

Publisher

Description

Data Source

[Book] Anorectal malformations in children2006

Author(s)

Publisher

Data Source

[Book] Postoperative electromanometrical, myographical and imaging evaluations. Anorectmations in children(AM Holschneider ed)2006

Author(s)

Publisher

Data Source

[Journal Article] Infrared spectrophotometry of intraluminal meconiumcalculi in a neonate with imperforate anus and rectal fistula2006

Author(s)

Journal Title

SHIMOTAKE Takashi 下竹孝志