fujiwara tomonori 藤原智徳

… Alternative Names

Fujiwara Tomonori 藤原智徳

FUJIWARA Tomonori 藤原智徳

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Researcher Number	90255399
Other IDs
Affiliation (Current)	2025: 埼玉医科大学, 保健医療学部, 教授
Affiliation (based on the past Project Information) *help	2024: 埼玉医科大学, 保健医療学部, 教授 2018 – 2019: 埼玉医科大学, 保健医療学部, 教授 2016 – 2017: 杏林大学, 医学部, 准教授 2014: 杏林大学, 医学部, 准教授 2011 – 2012: 杏林大学, 医学部, 准教授 … More 2004 – 2010: 杏林大学, 医学部, 講師 2007: Kyorin University, 医子部, 講師 2003: 杏林大学, 医学部, 助手 1995 – 1998: 杏林大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Basic Section 52030:Psychiatry-related / Basic / Social brain science / Neurochemistry/Neuropharmacology Except Principal Investigator Neurophysiology and muscle physiology / Neuroscience in general / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator 開口放出 / シンタキシン / HPC-1 / オキシトシン / ドパミン / 社会行動 / シナプス / SNARE蛋白質 / ノックアウトマウス / syntaxin … More / 行動学 / 神経科学 / シナプス関連分子 / シナプス関連 / シナプス関連蛋白質 / シナプス関連タンパク質 / 遺伝子組み換えマウス / 行動異常 / 遺伝子改変マウス / 遺伝子欠損マウス / 痙攣 / シナプス伝達 / 異常行動 / 行動解析 / マウス / シンタキシシ / 条件付け恐怖記憶 / SNARE / Syntaxin / 蛋白質リン酸化 / Tubulin … More Except Principal Investigator 開口放出 / シナプス伝達 / HPC-1 / シンタキシン1 / syntaxin1A / syntaxin1B / 遺伝子ノックアウトマウス / シンタキシン1B / シンタキシン1A / カイニン酸 / 最初期遺伝子 / 海馬 / 神経可塑性 / REGULATED SECRETION / NEURITE SPROUTING / EXOCYTOSIS / SYNTAXIN 1A / 長期増強 / 制御性分泌 / 神経発芽 / シンタキシン１ / シナプス / 海馬神経細胞 / シンタキシン / SNARE / syntaxin1 / ノックアウトマウス / 神経成長因子 / シンタキシン１B / haploid / 自閉性障害 / 遅い神経伝達物質放出過程 / 速い神経伝達物質放出過程 / シンタキシン１Ｂ / シンタキシン１A / BDNF / グリア細胞 / 機能分化 / 神経伝達 / 疾患モデル / 自閉症 / 運動障害 / 痙攣発作 / 致死 / 遅い神経伝達 / 速い神経伝達 / 行動異常 / シナプス伝達制御因子 / シナプス機能分化 / 疾患モデル動物 / ノックアウトマウス自閉性障害 / LTP Less

Regulation of DA homeostasis by OXTPrincipal Investigator
- Principal Investigator
  
  藤原智徳
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Saitama Medical University
Regulation of social behavior by reciprocal interaction between OXTergic and DAergic systemPrincipal Investigator
- Principal Investigator
  
  Fujiwara Tomonori
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic / Social brain science
- Research Institution
  Saitama Medical University
  Kyorin University
Functional difference between syntaxin1 isoforms in synaptic transmission
- Principal Investigator
  
  AKAGAWA kimio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Kyorin University
Functional role of syntaxin 1B in the regulation of synaptic vesicle exocytosis and of the readily releasable pool at central synapses
- Principal Investigator
  
  MISHIMA Tatsuya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Kyorin University
Studies for the functional difference of STX1A and STX1B in vivoPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Tomonori
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyorin University
Analysis of syntaxin 1 gene knockout mice as an animal model for autistic disorder
- Principal Investigator
  
  AKAGAWA Kimio
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyorin University
Behavioral analysis of syntaxin knockout micePrincipal Investigator
- Principal Investigator
  
  FUJIWARA Tomonori
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyorin University
シンタキシン1Aノックアウトマウスを用いた行動学的解析Principal Investigator
- Principal Investigator
  
  藤原智徳
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyorin University
開口放出関連蛋白質HPC-1の活性制御機構に関する研究Principal Investigator
- Principal Investigator
  
  藤原智徳
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyorin University
神経特異的蛋白失HPC-1の機能調節に関する解析Principal Investigator
- Principal Investigator
  
  藤原智徳
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyorin University
神経可塑性に関わる神経特異蛋白質HPC-1の研究
- Principal Investigator
  
  AKAGAWA Kimio
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyorin University
神経発芽におけるHPC-1の機能に関する研究Principal Investigator
- Principal Investigator
  
  藤原智徳
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kyorin University
STUDY OF A NEURON-SPECIFIC PROTEIN,HPC-1, WHICH REGULATES NEURONAL SPROUTING.
- Principal Investigator
  
  AKAGAWA Kimio
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  KYORIN UNIVERSITY

[Book] Recent Research Developments in Cell Science2004
- Author(s)
  T.Fujiwara
- Total Pages
  11
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-15700292
[Journal Article] A part of patients with autism spectrum disorder has haploidy of HPC-1/syntaxin1A gene that possibly caused behavioral disturbance as in experimentally gene ablated mice.2017
- Author(s)
  Kofuji T, Hayashi Y, Fujiwara T, Sanada M, Tamaru M, Akagawa K
- Journal Title
  
  Neuroscience letters
  
  Volume: 644 Pages: 5-9
- DOI
  10.1016/j.neulet.2017.02.052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07064, KAKENHI-PROJECT-16K01954
[Journal Article] A part of patients with autism spectrum disorder has haploidy of HPC-1/syntaxin1A gene that possibly causes behavioral disturbance as in experimentally gene ablated mice.2017
- Author(s)
  Kofuji T, Hayashi Y, Fujiwara T, Sanada M, Tamaru M, Akagawa K.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 644 Pages: 5-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01954
[Journal Article] Syntaxin 1B contributes to regulation of the dopaminergic system through GABA transmission in the CNS.2017
- Author(s)
  Fujiwara T, Kofuji T, Mishima T, Akagawa K
- Journal Title
  
  Eur J Neurosci.
  
  Volume: 46 Issue: 12 Pages: 2867-2874
- DOI
  10.1111/ejn.13779
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01954, KAKENHI-PROJECT-16K07064
[Journal Article] Unusual social behavior in HPC-1/syntaxin1A knockout mice is caused by disruption of the oxytocinergic neural system2016
- Author(s)
  T Fujiwara, M Sanada, T Kofuj and K Akagawa
- Journal Title
  
  J Neurochem
  
  Volume: 138 Issue: 1 Pages: 117-23
- DOI
  10.1111/jnc.13634
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K01954, KAKENHI-PROJECT-16K07064
[Journal Article] Presynaptic inhibitory actions of pregabalin on excitatory transmission in superficial dorsal horn of mouse spinal cord: further characterization of presynaptic mechanisms2014
- Author(s)
  Matsuzawa R, Fujiwara T, Nemoto K, Fukushima T, Yamaguchi S, Akagawa K, Hori Y
- Journal Title
  
  Neuroscience Letters
  
  Volume: 558 Pages: 186-191
- DOI
  10.1016/j.neulet.2013.11.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500468, KAKENHI-PROJECT-24300142
[Journal Article] Syntaxin 1B, but Not Syntaxin 1A, is Necessary for the Regulation of Synaptic Vesicle Exocytosis and of the Readily Releasable Pool at Central Synapses2014
- Author(s)
  T.Mishima, T.fujiwara, M.Sanada, T.Kofuji ,M.Kanai &K.Akagawa
- Journal Title
  
  PLoS ONE.
  
  Volume: 9 Issue: 2 Pages: e90004-e90004
- DOI
  10.1371/journal.pone.0090004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24300142, KAKENHI-PROJECT-24500462
[Journal Article] ＨＰＣ－１ｓｙntaxin1A and syntaxin1B play distinct roles in neuronal survival.2014
- Author(s)
  Ｔ．Ｋｏｆｕｊｉ，Ｔ．Ｆｕｊｉｗａｒａ，　Ｍ．Ｓａｎａｄａ，　Ｔ．Ｍｉｓｈｉｍａ　＆　Ｋ．Ａｋａｇａｗａ
- Journal Title
  
  J. Neurochemistry
  
  Volume: 129 Issue: 4 Pages: 514-525
- DOI
  10.1111/jnc.12722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300142, KAKENHI-PROJECT-24500462
[Journal Article] Oligomerised lychee fruit-derived polyphenol attenuates cognitive impairment in senescence-accelerated mice and endoplasmic reticulum stress in neuronal cells2013
- Author(s)
  Sakurai T, Kitadate K, Nishioka H, Fujii H, Ogasawara J, Kizaki T, Sato S, Fujiwara T, Akagawa K, Izawa T, Ohno H
- Journal Title
  
  Br J Nutr
  
  Volume: 28 Pages: 1-10
- Data Source
  KAKENHI-PROJECT-22500338
[Journal Article] Exercise training and the promotion of neurogenesis and neurite outgrowth in the hippocampus2012
- Author(s)
  Sakurai T, Ogasawara J, Kizaki T, Ishibashi Y, Fujiwara T, Akagawa K, Izawa T, Radak Z, Ohno H
- Journal Title
  
  J Phys Fitness Sports Med
  
  Volume: 1(2) Pages: 333-337
- NAID
  10031158961
- Data Source
  KAKENHI-PROJECT-22500338
[Journal Article] Impairment of Catecholamine Systems during Induction of Long-Term Potentiation at Hippocampal CA1 Synapses in HPC-1/Syntaxin 1A Knock-out MiceJ2012
- Author(s)
  T Mishima T Fujiwara T Kofuji and K Akagawa
- Journal Title
  
  Neurosci
  
  Volume: 32 Pages: 381-389
- Data Source
  KAKENHI-PROJECT-22500338
[Journal Article] Impairment of Catecholamine Systems during Induction of Long-Term Potentiation at Hippocampal CA1 Synapses in HPC-1/Syntaxin 1A Knock-out Mice2011
- Author(s)
  T Mishima, T Fujiwara, T Kofuji, K Akagawa
- Journal Title
  
  J.Neurosci
  
  Volume: 32 Pages: 381-389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500338
[Journal Article] LOSS OF GRANUPHILIN AND OF SYNTAXIN-1A CAUSE DIFFERENTIAL EFFECTS ON INSULIN GRANULE DOCKING AND FUSION2011
- Author(s)
  H Wang, R Ishizaki, E Kobayashi, T Fujiwara, K Akagawa, T Izumi
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 32244-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500338
[Journal Article] Involvement of leucine zipper transcription factor-like protein 1 (Lztfl1) in the attenuation of cognitive impairment by exercise training2011
- Author(s)
  T Sakurai, J Ogasawara, T Kizaki, Y Ishibashi, T Fujiwara, K Akagawa, T Izawa, S Oh-ishi, S Haga, H Ohno
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 416 Pages: 125-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500338
[Journal Article] Dysfunction of the Hypothalamic-Pituitary-Adrenal axis in STX1A KO mice2011
- Author(s)
  Fujiwara T, Kofuji T, Akagawa K
- Journal Title
  
  J Neuroendocrinol
  
  Volume: 23 Pages: 1222-1230
- Data Source
  KAKENHI-PROJECT-22500338
[Journal Article] LOSS OF GRANUPHILIN AND OF SYNTAXIN-1A CAUSE DIFFERENTIAL EFFECTS ON INSULIN GRANULE DOCKING AND FUSIONHPC-1/syntaxin 1A gene knockout mice show abnormal behavior possibly related to a disruption in 5-HTergic systems2011
- Author(s)
  H Wang, R Ishizaki, E Kobayashi, T Fujiwara, K Akagawa and T Izumi
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 32244-50
- Data Source
  KAKENHI-PROJECT-22500338
[Journal Article] Unusual retinal layer organization in HPC-1/syntaxin 1A knockout mice2011
- Author(s)
  Kaneko Y, Suge R, Fujiwara T, Akagawa K, Watanabe SI
- Journal Title
  
  J Mol Histol
  
  Volume: 42 Pages: 483-9
- Data Source
  KAKENHI-PROJECT-22500338
[Journal Article] Involvement of leucine zipper transcription factor-like protein 1 (Lztfl1)in the attenuation of cognitive impairment by exercise training2011
- Author(s)
  T Sakurai, J Ogasawara, T Kizaki, Y Ishibashi, T Fujiwara, K Akagawa, T Izawa, S Oh-ishi, S Haga, H Ohno
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 416 Pages: 125-129
- Data Source
  KAKENHI-PROJECT-22500338
[Journal Article] HPC-1/syntaxin 1A gene knockout mice show abnormal behavior possibly related to a disruption in 5-HTergic systems2010
- Author(s)
  Fujiwara, et al
- Journal Title
  
  Eur.J.Neurosci.
  
  Volume: 32 Pages: 99-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500338
[Journal Article] J. Neurosci2010
- Author(s)
  T Fujiwara, M Snada, T Kofuji, T Yoshikawa and K Akagawa
- Journal Title
  
  Eur
  
  Volume: 32 Pages: 99-107
- Data Source
  KAKENHI-PROJECT-22500338
[Journal Article] Transient silencing of synaptic transmitter release from specific neuronal types by recombinant tetanus toxin light chain fused to antibody variable region.2008
- Author(s)
  Kobayashi T, Kai N, Kobayashi K, Fujiwara T, Akagawa K, Onda M, Kobayashi K.
- Journal Title
  
  J Neurosci Methods 177
  
  Pages: 125-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18700368
[Journal Article] Transient silencing of synaptic transmitter release from specific neuronal types by recombinant tetanus toxin light chain fused to antibody variable region2008
- Author(s)
  T. Kobayashi, N. Kai, K. Kobayashi, T. Fujiwara, K. Akagawa, M. Onda, K. Kobayashi
- Journal Title
  
  J. Neurosci. Methods vol.175
  
  Pages: 125-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300133
[Journal Article] Imaging analysis reveals mechanistic differences between first- and se cond- phase insulin exocytosis.2007
- Author(s)
  Ohara-Imaizumi M, Fujiwara T, et. al.
- Journal Title
  
  J Cell Biol. 177
  
  Pages: 695-705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18700368
[Journal Article] Enhancement of synaptic transmission and nociceptive behaviour in HPC-1/syntaxin 1A knockout mice following peripheral nerve injury.2007
- Author(s)
  Takasusuki T. Fujiwara T., et al.
- Journal Title
  
  Eur. J. Neurosci. 26
  
  Pages: 2179-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18700368
[Journal Article] Enhancement of synaptic transmission and nociceptive behaviour in HPC-l/suntaxin 1A knockout mice following peripheral nerve injury.2007
- Author(s)
  Takasusuki T, Fujiwara T, et. al.
- Journal Title
  
  Eur. J. Neurosci. 26
  
  Pages: 2179-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18700368
[Journal Article] Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis.2007
- Author(s)
  Ohara-Imaizumi M, Fujiwara T, Nakamichi Y, Okamura T, Akimoto Y, Kawai J, Matsushima S, Kawakami H, Watanabe T, Akagawa K, Nagamatsu S.
- Journal Title
  
  J Cell Biol 177(4)
  
  Pages: 695-705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18700368
[Journal Article] Analysis of knockout mice to determine the role of HPC-1/syntaxin 1A in expressing synaptic plasticity2006
- Author(s)
  T.Fujiwara, et al.
- Journal Title
  
  J.Neurosience (submitted)
- Data Source
  KAKENHI-PROJECT-15700292
[Journal Article] Analysis of knockout mice to determine the role of HPC-1/syntaxin 1A in expressing synaptic plasticity2006
- Author(s)
  T.Fujiwara, et al.
- Journal Title
  
  J. Neurosience 26 (21)
  
  Pages: 5767-5776
- Data Source
  KAKENHI-PROJECT-18700368
[Journal Article] Analysis of Knock-Out Mice to Determine the Role of HPC-1/Syntaxin 1A in Expressing Synaptic Plasticity2006
- Author(s)
  Tomonori Fujiwara, Tatsuya Mishima, Takefumi Kofuji, Tomoki Chiba, Keiji Tanaka, Akitsugu Yamamoto, and Kimio Akagawa
- Journal Title
  
  The Journal of Neuroscience 26(21)
  
  Pages: 5767-5776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18700368
[Journal Article] HPC-1/syntaxin 1A gene knockout mice show abnormal behavior possibly related to a disruption in 5-HTergic systems.
- Author(s)
  T. Fujiwara, M. Sanada, T. Kofuji, T. Yoshikawa, K. Akagawa
- Journal Title
  
  Eur. J. Neurosci (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300133
[Journal Article] HPC-1/syntaxin 1A gene knockout mice show abnormal behavior possibly related to a disruption in 5-HTergic systems.
- Author(s)
  T.Fujiwara, et al.
- Journal Title
  
  Eur.J.Neuroscience (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300133
[Presentation] Syntaxin1A knockout mice showed unusual social behavior in their homecage.2020
- Author(s)
  T Fujiwara, T Kofuji, T Furukawa and K Akagawa
- Organizer
  FENS2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01954
[Presentation] Seizure phenotype in syntaxin1B gene knockout mice was caused by impaired GABAergic system2019
- Author(s)
  Kofuji T, Mishima T, Fujiwara T, A Saito, Terao Y, Akagawa K
- Organizer
  日本神経科学
- Data Source
  KAKENHI-PROJECT-16K01954
[Presentation] Role of syntaxin1B in GABA-mediated regulation of network activities:　Behavioral and neuronal analysis of fever-associated epilepsy syndromes in syntaxin1B gene-ablated mice2019
- Author(s)
  T Mishima, T Fujiwara, T Kofuji, A Saito, Y Terao and K Akagawa
- Organizer
  日本神経科学
- Data Source
  KAKENHI-PROJECT-16K01954
[Presentation] Syntaxin1B contributes to regulation of the dopaminergic system through GABA transmission in the CNS.2018
- Author(s)
  T Fujiwara, T Kofuji, T Mishima, Y Terao and K Akagawa
- Organizer
  11th FENS Forum of Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01954
[Presentation] Unusual social behavior in HPC-1/syntaxin1A knockout mice2018
- Author(s)
  T Fujiwara, T Kofuji, T Mishima, Y Terao and K Akagawa
- Organizer
  日本生理学会
- Data Source
  KAKENHI-PROJECT-16K01954
[Presentation] HPC-1/syntaxin 1A regulates the cortical signal propagation by affecting the GABAergic transmission.2018
- Author(s)
  Osanai M, Matsumura A, Fujiwara T, Kikuta S, Yagi T, Akagawa K.
- Organizer
  11th FENS Forum of Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01954
[Presentation] A study on the seizure phenotype of syntaxin 1B gene-ablated mice2017
- Author(s)
  Mishima T, Fujiwara T, Kofuji T, Terao Y and Akagawa K
- Organizer
  日本生理学会
- Data Source
  KAKENHI-PROJECT-16K01954
[Presentation] A study on the behavioral and neuronal phenotype of syntaxin 1B gene-ablated mice: involvement of syntaxin 1B in the fever-associated epilepsy syndromes2017
- Author(s)
  Mishima T, Fujiwara T, Kofuji T, Terao Y and Akagawa K
- Organizer
  日本神経科学会
- Data Source
  KAKENHI-PROJECT-16K01954
[Presentation] シンタキシン1B遺伝子欠損マウスのけいれん表現型の解析2017
- Author(s)
  T Mishima, T Fujiwara, T Kofuji and K Akagawa
- Organizer
  日本生理学会
- Place of Presentation
  浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K01954
[Presentation] Five Cases of Autism Spectrum Disorder with Syntaxin1A Gene Haploidy2017
- Author(s)
  Kofuji T, Hayashi Y, Fujiwara T, Sanada M, Tamaru M, and Akagawa K
- Organizer
  AOCCN
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01954
[Presentation] HPC-1/syntaxin1A is one of causative gene for autistic spectrum disorder.2016
- Author(s)
  T Fujiwara, T Kofuji, T Mishima, Y Hayashi, M Tamaru, K Akagawa
- Organizer
  日本神経科学会
- Place of Presentation
  横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16K01954
[Presentation] HPC-1/STX1AおよびSTX1Bによる社会行動の制御2014
- Author(s)
  藤原智徳、小藤剛史、三嶋竜弥、赤川公朗
- Organizer
  日本生理学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24500462
[Presentation] シナプス伝達におけるシンタキシン1Bの生理機能2014
- Author(s)
  三嶋竜弥、藤原智徳、真田ますみ、小藤剛史、赤川公朗
- Organizer
  日本生理学会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-24500462
[Presentation] 神経細胞の生存に対するHPC-1/シンタキシン1Aとシンタキシン1Bの異なる役割2013
- Author(s)
  小藤剛史、藤原智徳、真田ますみ、三嶋竜弥、赤川公朗
- Organizer
  日本神経科学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24500462
[Presentation] STX1A, STX1B欠損マウスにおける行動異常の比較2013
- Author(s)
  藤原智徳、小藤剛史、三嶋竜也、赤川公朗
- Organizer
  日本神経科学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24300142
[Presentation] 神経細胞の生存に対するHPC-1/シンタキシン１Ａとシンタキシン１Ｂの異なる役割2013
- Author(s)
  小藤剛史、藤原智徳、真田ますみ、三嶋竜也、赤川公朗
- Organizer
  日本神経科学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24300142
[Presentation] STX1A、STX1B欠損マウスにおける行動異常の比較2013
- Author(s)
  藤原智徳、小藤剛史、三嶋竜弥、赤川公朗
- Organizer
  日本神経科学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24500462
[Presentation] STX1A and STX1B knockout mice exhibited autistic disorder and schizophrenia like neuropsychological abnormalities, respectively.2013
- Author(s)
  Tomonori Fujiwara
- Organizer
  日本神経科学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] DA release in STX1B heterozygous mutant mice was increased in vivo, but not in vitro2012
- Author(s)
  T Fujiwara, T Kofuji, T Mishima and K Akagawa
- Organizer
  日本神経科学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] Diminishment of the cortical signal propagation in HPC-1 / syntaxin 1A knockout mice2012
- Author(s)
  M Osanai, A Matsumura, T Fujiwara, I Mori, K Akagawa, T Yagi
- Organizer
  日本生理学会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] Functional differences between syntaxin1A and syntaxin1B in fast synaptic transmission2012
- Author(s)
  T Mishima, T Fujiwara, M Sanada T Kofuji, and K Akagawa
- Organizer
  日本神経科学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] DA release in STX 1B heterozygous mutant mice was increased in vivo, but not in vitro.2012
- Author(s)
  T. Fujiwara
- Organizer
  日本神経科学会
- Place of Presentation
  名古屋
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-24300142
[Presentation] シナプス伝達におけるシンタキシン1Aとシンタキシン1Bの機能的差異2012
- Author(s)
  三嶋竜弥、藤原智徳、真田ますみ、小藤剛史、赤川公朗
- Organizer
  日本神経科学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24500462
[Presentation] DA release in STX1B heterozygous mutant mice was increased in vivo, but not in vitro.2012
- Author(s)
  Tomonori Fujiwara
- Organizer
  日本神経科学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] Glial cells from STX1B-KO mice were less effective on neuronal survival than WT2012
- Author(s)
  T Kofuji, T Fujiwara, T Mishima and K Akagawa
- Organizer
  日本神経化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] A study on the neuronal phenotype of swtaxin1B knockout mice : implication of differential role of syntaxin1A and syntaxin1B in synaptic transmission2011
- Author(s)
  T Mishima, T Fujiwara, M Sanada, T Kofuji, K Akagawa
- Organizer
  日本神経科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] oligonolの老化促進モデルマウスの認知機能障害に対する予防効果と海馬におけるターゲト分子の同定2011
- Author(s)
  櫻井拓也、北舘健太郎、西岡浩、若命浩二、藤井創、小笠原準悦、木崎節子、石橋義永、藤原智徳、赤川公朗、中野法彦、井澤鉄也、大野秀樹
- Organizer
  統合医療機能性食品国際会議
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] Analyses of insulin-granule docking and fusion in Granuphilin- and/or Syntaxin-1a-knockout mice2011
- Author(s)
  R Ishizaki, H Wang, T Fujiwara, K Akagawa, T Izumi
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] The genetic analysis of HPC-1/STX1A and STX1B revealed the distinctive functions in vivo2011
- Author(s)
  T Fujiwara, T Kofuji, T Mishima, K Akagawa
- Organizer
  日本生理学会
- Place of Presentation
  横浜(誌上開催)
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] oligonolは神経細胞において小胞体ストレスを減弱させる2011
- Author(s)
  櫻井拓也、北舘健太郎、西岡浩、若命浩二、藤井創、小笠原準悦、石橋義永、木崎節子、藤原智徳、赤川公郎、炭谷由計、石田均、芳賀脩光、大野秀樹
- Organizer
  日本予防医学学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] oligonolは神経細胞において小胞体ストレスを減弱させる2011
- Author(s)
  櫻井拓也、北舘健太郎、西岡浩、若命浩二、藤井創、小笠原準悦、石橋義永、木崎節子、藤原智徳、赤川公朗、炭谷由計、石田均、芳賀脩光、大野秀樹
- Organizer
  日本予防医学学会
- Place of Presentation
  東京東京
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] A study on the neuronal phenotype of syntaxin1B knockout mice: implication of differential role of syntaxin1A and syntaxin1B in synaptic transmission2011
- Author(s)
  T Mishima, T Fujiwara, M Sanada, T Kofuji, K Akagawa
- Organizer
  日本神経科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] Diminishment of the cortical signal propagation in HPC-1 / syntaxin 1A knockout mice2011
- Author(s)
  M Osanai, A Matsumura, T Fujiwara, I Mori, K Akagawa, T Yagi
- Organizer
  日本神経科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] Distinct roles of HPC-1/STX1A and STX1B in neuronal survival2011
- Author(s)
  T Kofuji, T Fujiwara, M Sanada, T Mishima, K Akagawa
- Organizer
  日本神経科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] Analyses of insulin-granule docking and fusion in Granuphilin- and/or Syntaxin-1aknockout mice2011
- Author(s)
  R Ishizaki, H Wang, T Fujiwara, K Akagawa, and T Izumi
- Organizer
  日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] Diminishment of the cortical signal propagation in HPC-1/syntaxin 1A knockout mice2011
- Author(s)
  M Osanai, A Matsumura, T Fujiwara, I Mori, K Akagawa, T Yagi
- Organizer
  日本神経科学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] The genetic analysis of HPC-1/STX1A and STX1B revealed the distinctive functions in vivo2011
- Author(s)
  T Fujiwara, T Kofuji, T Mishima and K Akagawa
- Organizer
  日本生理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] A study on the phenotype of syntaxin1B knockout mice2010
- Author(s)
  T Fujiwara, M Sanada, T Kofuji, T Mishima and K Akagawa
- Organizer
  日本神経科学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] 老化促進モデルマウスの認知機能障害に対してoligonolは運動と同様に予防効果を持つ2010
- Author(s)
  櫻井拓也、北舘健太郎、西岡浩、若命浩二、藤井創、小笠原準悦、木崎節子、石橋義永、藤原智徳、赤川公朗、中野法彦、斉藤大蔵、根本浩一郎、芳賀脩光、大野秀樹
- Organizer
  統合医療機能性食品国際会議
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] HPC-1/STX1A and STX1B might have distinct roles in neuronal function2010
- Author(s)
  T Fujiwara, T Kofuji, T Mishima, MKanai-Azuma and K Akagawa
- Organizer
  日本生理学会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] Impaired induction of long-term potentiation in HPC-1/syntaxin 1A knockout mice may be due to altered catecholaminergic system2010
- Author(s)
  T Mishima, T Fujiwara, T Kofuji, K Akagawa
- Organizer
  日本神経科学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] HPC-1/STX1A and STX1B might have distinct roles in neuronal function.2010
- Author(s)
  Fujiwara, et al
- Organizer
  日本生理学会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-22500338
[Presentation] Phenotype analysis of syntaxin1B knockout mice2009
- Author(s)
  T. Fujiwara
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-19300133
[Presentation] Genetic Analysis of syntaxinl function.2009
- Author(s)
  T.Fujiwara, et al.
- Organizer
  International Congress of Physiological Science.
- Place of Presentation
  Kyoto Japan
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-19300133
[Presentation] Genetic analysis of syntaxin 1 function2009
- Author(s)
  T. Fujiwara
- Organizer
  36th International Union of Physiological Science
- Place of Presentation
  Kyoto
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-19300133
[Presentation] Phenotype analysis of syntaxin1B knockout mice.2009
- Author(s)
  T.Fujiwara, et al.
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-19300133
[Presentation] A case of peripheral nervous system abnormality in HPC-1/syntaxin1A knockout mice2008
- Author(s)
  Yuko Kaneko, Rie Suge, Tomonori Fujiwara, Kimio Akagawa and Shu-Ichi Watanabe
- Organizer
  日本生理学会
- Place of Presentation
  京王プラザ
- Data Source
  KAKENHI-PROJECT-18700368
[Presentation] KOBAYASHI Functional analysis of the striatopallidal neural pathway by conditional transmission silencing2008
- Author(s)
  T. KOBAYASHI, N. KAI, K. KOBAYASHI, T. FUJIWARA, K. AKAGAWA, M. ONDA, I. PASTAN, K.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Washington, DC.
- Data Source
  KAKENHI-PROJECT-18700368
[Presentation] Functional analysis of the striatopallidal neural pathway by conditional transmission silencing2008
- Author(s)
  T. KOBAYASHI, N. KAI, K. KOBAYASHI, T. FUJIWARA, K. AKAGAWA, M. ONDA, I. PASTAN, K. KOBAYASHI
- Organizer
  神経科学会
- Place of Presentation
  東京ビックサイト
- Data Source
  KAKENHI-PROJECT-18700368
[Presentation] Effects of 5-HT signaling on cultured hippocampal neurons of HPC-1 /syntaxinl A knock-out mouse2008
- Author(s)
  T. Fujiwara, et. al.
- Organizer
  日本生理学会
- Place of Presentation
  京王プラザ
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18700368
[Presentation] HPC-1/syntaxin1Aノックアウトマウスの培養海馬神経細胞に対する5HTシグナルの影響ナノレの影響2008
- Author(s)
  T.Fujiwara
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京
- Year and Date
  2008-03-25
- Data Source
  KAKENHI-PROJECT-19300133
[Presentation] Effects of 5-HT signaling on cultured hippocampal neurons of HPC-1/syntaxin1A knock-out mouse2008
- Author(s)
  Tomonori Fujiwara, Takefumi Kofuji, Tatsuya Mishima and Kimio Akagawa
- Organizer
  日本生理学会
- Place of Presentation
  京王プラザ
- Data Source
  KAKENHI-PROJECT-18700368
[Presentation] Masumi Sanada and Kimio Akagawa Impairment of HPA-axis in HPC-1/syntaxin1A knockout mice2008
- Author(s)
  Takefumi Kofuji, Tomonori Fujiwara
- Organizer
  日本神経化学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-18700368
[Presentation] Deletion of HPC-1/syntaxinlA gene causes autistic behavior in mice2007
- Author(s)
  T. Fujiwara, et. al.
- Organizer
  神経科学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-18700368
[Presentation] Deletion of HPC-1/syntaxin1A gene causes autistic behavior in mice2007
- Author(s)
  Tomonori Fujiwara, Takefumi Kofuji, Tatsuya Mishima, Takeo Yoshikawa and Kimio Akagawa
- Organizer
  神経科学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18700368
[Presentation] Deletion of HPC-1/syntaxin1A gene causes autistic behavior in mice.2007
- Author(s)
  T.Fujiwara
- Organizer
  第30回日本神経料学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19300133
[Presentation] Autistic-behavior in HPC-1/syntaxin1A knockout mice2007
- Author(s)
  Tomonori Fujiwara, Rie Suge, Takefumi Kofuji, Tatsuya Mishima, Akiko Watanabe, Takeo Yoshikawa, Masahiko Nomura and Kimio Akagawa
- Organizer
  日本生理学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18700368
[Presentation] Deletion of HPC-1/syntaxin1A gene causes autistic behavior in mice2007
- Author(s)
  T. Fujiwara
- Organizer
  第30回神経科学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19300133
[Presentation] Behavioral analysis of HPC-1/syntaxin1A knock-out mouse2006
- Author(s)
  Tomonori Fujiwara, Tatsuya Mishima, Takefumi Kofuji and Kimio Akagawa
- Organizer
  日本神経科学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18700368
[Presentation] HPC-1/syntaxin1A knockout mice exhibit autistic-like behavior2006
- Author(s)
  Takefumi Kofuji, Tomonori Fujiwara, Tatsuya Mishima, Akiko Watanabe, Takeo Yoshikawa and Kimio Akagawa
- Organizer
  日本神経化学会
- Place of Presentation
  名古屋
- Year and Date
  2006-09-14
- Data Source
  KAKENHI-PROJECT-18700368
[Presentation] 自閉症スペクトラム障害とHPC-1/syntaxinA遺伝子発現異常の関連性の検討
- Author(s)
  小藤剛史、林優子、藤原智徳、真田ますみ、田丸政男、赤川公朗
- Organizer
  日本神経化学会大会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-24300142

1. MISHIMA Tatsuya (40317095)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
2. AKAGAWA Kimio (80129303)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. SAITOU Ayako (80424109)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. FUJINO Ichiro (30265764)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SUGA Kei (30306675)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KOFUJI Takefumi (40365200)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. SANADA Masumi (70424108)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. NAKAYAMA Takahiro (90342823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OSANAI Makoto (90286419)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMAGUCHI Kazuhiko (00191221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 九島洋一 (30255400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 堀雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

fujiwara tomonori 藤原 智徳

Fujiwara Tomonori 藤原 智徳

FUJIWARA Tomonori 藤原 智徳

Research Projects

Research Products

Co-Researchers

Regulation of DA homeostasis by OXTPrincipal Investigator

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Review Section

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Regulation of social behavior by reciprocal interaction between OXTergic and DAergic systemPrincipal Investigator

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Functional difference between syntaxin1 isoforms in synaptic transmission

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Functional role of syntaxin 1B in the regulation of synaptic vesicle exocytosis and of the readily releasable pool at central synapses

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Studies for the functional difference of STX1A and STX1B in vivoPrincipal Investigator

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Analysis of syntaxin 1 gene knockout mice as an animal model for autistic disorder

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Behavioral analysis of syntaxin knockout micePrincipal Investigator

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シンタキシン1Aノックアウトマウスを用いた行動学的解析Principal Investigator

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開口放出関連蛋白質HPC-1の活性制御機構に関する研究Principal Investigator

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神経特異的蛋白失HPC-1の機能調節に関する解析Principal Investigator

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神経可塑性に関わる神経特異蛋白質HPC-1の研究

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神経発芽におけるHPC-1の機能に関する研究Principal Investigator

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STUDY OF A NEURON-SPECIFIC PROTEIN,HPC-1, WHICH REGULATES NEURONAL SPROUTING.

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fujiwara tomonori 藤原智徳

Fujiwara Tomonori 藤原智徳

FUJIWARA Tomonori 藤原智徳