NAGAYASU HIROKI 永易裕樹

… Alternative Names

NAGAYASU Hiroki 永易裕樹

永易裕樹ナガヤスヒロキ

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Researcher Number	90265075
Other IDs
External Links
Affiliation (Current)	2025: 北海道医療大学, 歯学部, 教授
Affiliation (based on the past Project Information) *help	2016 – 2025: 北海道医療大学, 歯学部, 教授 2011 – 2013: 北海道医療大学, 歯学部, 教授 2010: 北海道医療大学, 個体差医療科学センター, 教授 2009: 北海道医療大学, 個体差医療科学センター, 准教授 2007: 北海道医療大学, 個体差医療科学センター, 準教授 … More 2006 – 2007: Health Sciences University of Hokkaido, Department of Dental Science, Institute of Personalized Medical Science, Associate Professor, 個体差医療科学センター, 准教授 2005: 北海道医療大学, 個体差医療科学センター, 助教授 2002 – 2004: HEALTH SCL. UNIV. OF HOKKAIDO, SCHOOL OF DENT., ASSOCIATE PROFESSOR, 歯学部, 助教授 2001 – 2002: Health Sciences University of Hokkaido, School of dentistry, Lecturer, 歯学部, 講師 1997 – 2001: 北海道医療大学, 歯学部, 助手 1995: 北海道医療大学, 歯学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry / Surgical dentistry / 病態科学系歯学(含放射線系歯学) Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Surgical dentistry / Pathobiological dentistry/Dental radiology / Surgical dentistry
Keywords	Principal Investigator gap junction / metastasis / invasion / 口腔がん / anticancer drug / oral cancer / EGF / connexin43 / 転移 / DNAメチル化剤 … More / DNA脱メチル化剤 / エピゲノム / エピジェネティクス / 噛みタバコ / SIRT1 / アレコリン / betel quid / genomic instability / cell motility / malignant pehenotype / 活性酸素 / 遺伝子不安定性 / 悪性化進展 / 運動能 / 浸潤能 / 遺伝的不安定性 / 細胞運動能 / 悪性形質 / 浸潤 / lung metastasis / cell to cell adhesion / vascular endothelial cell / 肺転移 / 細胞間結合装置 / 血管内皮細胞 / 悪性化形質 / 浸油 / 上皮成長因子(EGF) … More Except Principal Investigator INVASION / EGF / ORAL CANCER / SCC / HUMAN / MATASTASIS / METASTASIS / 唾液腺内視鏡 / 溶解療法 / クエン酸 / 唾石 / 唾石摘出 / オルガノイド / 化合物スクリーニング / ゲノム編集 / 口腔潜在的悪性疾患 / CTGF / 転移 / 浸潤 / トランスクリプトーム / プロテオーム / 被包化 / 被膜化 / 口腔扁平上皮癌 / 肝細胞癌 / 破砕術 / 次亜塩素酸ナトリウム水溶液 / クエン酸水溶液 / 次亜塩素酸ナトリウム / 唾液腺内視鏡下唾石溶解療法 / 内視鏡 / 唾液腺 / 唾石摘出術 / 併用療法 / 唾石溶解術 / 溶解剤 / 唾石溶解療法 / 唾石破砕術 / Lymphoma / Squamous cell carcinoma / DNA vaccine / Gene therapy / Antitumor / Beta-defensin / CCR6 / 遺伝子導入 / 樹状細胞 / リンパ腫 / 扁平上皮癌 / DNAワクチン / 遺伝子治療 / 抗腫瘍性 / βディフェンシン / METASTAIZS / INVASIN / 破砕 / 把持 / 低侵襲 / adrenomedullin / HIF-1 / 口腔癌 / アポトーシス / pim-1 / セリンスレオニンカイネース / アドレノメジュリン阻害 / アドレノメジュリン / 遺伝子発現 / 腫瘍増殖 / 血管新生阻害剤 / 血管新生 / 低酸素 Less

薬剤耐性口腔扁平上皮癌に対するドライバー遺伝子変異を標的とした治療法の開発Principal Investigator
- Principal Investigator
  
  永易裕樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
Development of Oral Epithelial Dysplasia Inhibitors Focusing on CTGF
- Principal Investigator
  
  堀江尚弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
口腔扁平上皮癌の浸潤・転移を防ぐための腫瘍組織被包化の開発
- Principal Investigator
  
  藏滿保宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
Comprehensive analysis of epigenomic aberrant genes in oral cancer and verification of tumor suppressive effect by epigenomic drugs.Principal Investigator
- Principal Investigator
  
  NAGAYASU Hiroki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
Basic study on the development of combination therapy with the lithotripsy and double litholysis using protein and calcic dissolution liquid under sialendoscopy
- Principal Investigator
  
  NAKAYAMA Eiji
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Health Sciences University of Hokkaido
Elucidation of the carcinogenic mechanism for the prevention of oral cancer caused by betel quid chewingPrincipal Investigator
- Principal Investigator
  
  NAGAYASU Hiroki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Health Sciences University of Hokkaido
Basic study on development of the sialendoscopic dissolution therapy for sialolith: Analysis of the solubilizers
- Principal Investigator
  
  NAKAYAMA EIJI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Health Sciences University of Hokkaido
Fundamental study on the reduction of invasiveness for the sialoendoscopic laser sialolithotripsy in the combination with forceps removal method
- Principal Investigator
  
  NAKAYAMA Eiji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Health Sciences University of Hokkaido
Establishment of optimal anti-angiogenic therapy against cancer of oral cavity
- Principal Investigator
  
  KOBAYASHI Masanobu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Health Sciences University of Hokkaido
Study of the inhibitory effects on malignant progression and anticancer drug sensitivity of human squamous cell carcinoma by intensifying cell to cell communicationPrincipal Investigator
- Principal Investigator
  
  NAGAYASU Hiroki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Health Sciences University of Hokkaido, Institute of Personalized Medical Science
Antitumor effect of gene transfection and DNA vacccine of beta-defensins
- Principal Investigator
  
  ABIKO Yoshihiro
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Health Sciences University of Hokkaido
Study of the effects of epidermal growth factor on genomic instability and malignant phenotype of oral squamous cell carcinoma cellsPrincipal Investigator
- Principal Investigator
  
  NAGAYASU Hiroki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Health Sciences University of Hokkaido
Study of the inhibitory effects on invasion and metastasis of human squamous cell carcinoma by intensifying endothelial cell to cell adhesionPrincipal Investigator
- Principal Investigator
  
  NAGAYASU Hiroki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Health Sciences University of Hokkaido, School of dentistry
ANALYSIS OF THE SIGNAL TRANSDUCTION OF CELL MOTILITY INDUCED BY EGF STIMULATION IN HUMAN ORAL CANCER CELLS
- Principal Investigator
  
  SHIBATA Tohiyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  GIFU UNIVERSITY
ANALYSIS OF SIGNAL TRANSDUCTION OF CELL MOTILITY INDUCED BY EGF STIMULATION IN HUMAN ORAL SQUAMOUS CELL CARCINOMA
- Principal Investigator
  
  SHIBATA Toshiyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  HEALTH SCIENCES UNIVERSITY OF HOKKAIDO
ENHANCING EFFECTS OF EPIDERMAL GROWTHFACTOR ON HUMAN ORAL SQUAMOUS CELL CARCINOMA CELL MOTILITY AND ANALYSIS OF INTERCELLULER SIGNAL TRANSDUCTION
- Principal Investigator
  
  SHIBATA Toshiyuki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  HEALTH SCIENCES UNIVERSITY OF HOKKAIDO
上皮成長因子(ESF)が癌細胞の悪性化形質獲得および遺伝的不安定性に与える影響Principal Investigator
- Principal Investigator
  
  永易裕樹
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Health Sciences University of Hokkaido

All 2023 2022 2021 2020 2019 2017 2013 2012 2011 2007 2006

All Journal Article Presentation

[Journal Article] Downregulating effect of a standardized extract of cultured Lentinula edodes mycelia on cortactin in prostate cancer cells is depended on malignant potential.2023
- Author(s)
  Yamashita S, Tanaka Y, Kitagawa T, Baron B, Tokuda K, Paudel D, Nakagawa K, Ohta T, Hamada J, Kobayashi M, Nagayasu H, Kuramitsu Y.
- Journal Title
  
  Anticancer Reserch
  
  Volume: 43 Issue: 3 Pages: 1159-1166
- DOI
  10.21873/anticanres.16261
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K10229, KAKENHI-PROJECT-20K09790
[Journal Article] Medial clavicle fracture with bone destruction after radical neck dissection combined with postoperative chemotherapy for secondary cervical lymph node metastasis of tongue cancer: a case report2021
- Author(s)
  Tashiro Masayasu、Sano Tomoaki、Sugiura Kazutaka、Minamida Yasuhito、Abiko Yoshihiro、Nagayasu Hiroki、Nakayama Eiji
- Journal Title
  
  Oral Radiology
  
  Volume: 37 Issue: 4 Pages: 1-5
- DOI
  10.1007/s11282-021-00515-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10273
[Journal Article] Intraosseous clear cell mucoepidermoid carcinoma in the maxilla: A case report and review of literature.2021
- Author(s)
  Harada Fumiya, Abiko Yoshihiro, Khurelchuluun Ariuntsetseg, Yoshida Koki, Takeda Shigehiro, Nakayama Eiji, Shimo Tsuyoshi, Nagayasu Hiroki
- Journal Title
  
  Clinical Case Reports
  
  Volume: 9 Issue: 7 Pages: 1-7
- DOI
  10.1002/ccr3.4447
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10273
[Journal Article] A challenging diagnosis of a mucocele in the maxillary gingiva: Case report and literature review.2021
- Author(s)
  Nagwan Elsayed, Tsuyoshi Shimo, Fumiya Harada, Daichi Hiraki, Masayasu Tashiro, Eiji Nakayama, Yoshihiro Abiko, Hiroki Nagayasu
- Journal Title
  
  International Journal of Surgery Case Reports
  
  Volume: 84 Pages: 1-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10273
[Journal Article] Tooth extraction in a patient with juvenile osteoporosis and cardiovascular disease2020
- Author(s)
  Tsuyoshi Shimo, Fumiya Harada, Kazuhiro Miyamoto, Tatsuji Odachi, Masahiro Ishikawa, Karnoon Shamsoon, Tomofumi Kawakami, Yoshihiro Abiko, Eiji Nakayama, Hiroki Nagayasu
- Journal Title
  
  Surgery and Rehabilitation
  
  Volume: 4 Pages: 1-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10273
[Journal Article] Asymptomatic submandibular giant calculus left for 24 years: A case report2020
- Author(s)
  Karnoon Shamsoon, Fumiya Harada, Shintaro Yodogawa, Shigehiro Takeda, Saki Fujii, Yoshihiro Abiko, Eiji Nakayama, Takashi, Saito, Hiroki Nagayasu, Tsuyoshi Shimo
- Journal Title
  
  Surgery and Rehabilitation
  
  Volume: 4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10273
[Journal Article] Masticatory Muscle Tendon-Aponeurosis Hyperplasia That Was Difficult to Diagnose Preoperatively2020
- Author(s)
  Nagwan Elsayed, Tsuyoshi Shimo, Fumiya Harada, Shigehiro Takeda,Yasuhito Minamida, Daichi Hiraki, Marie Wakabayashi, Kohei Sato, Yoshihiro Abiko, Masayasu Tashiro, Eiji Nakayama,Tomofumi Kawakami,Hiroki Nagayasu
- Journal Title
  
  Surgery and Rehabilitation
  
  Volume: 4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10273
[Journal Article] Disuse atrophy of masticatory muscles after intracranial trigeminal schwannoma resection: A case report and review of literature2020
- Author(s)
  Elsayed Nagwan、Shimo Tsuyoshi、Tashiro Masayasu、Nakayama Eiji、Nagayasu Hiroki
- Journal Title
  
  International Journal of Surgery Case Reports
  
  Volume: 75 Pages: 23-28
- DOI
  10.1016/j.ijscr.2020.08.059
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10273
[Journal Article] Asymptomatic submandibular giant calculus left for 24 years: A case report2020
- Author(s)
  Shamsoon Karnoon、Harada Fumiya、Yodogawa Shintaro、Takeda Shigehiro、Fujii Saki、Abiko Yoshihiro、Nakayama Eiji、Saito Takashi、Nagayasu Hiroki、Shimo Tsuyoshi
- Journal Title
  
  Surgery and Rehabilitation
  
  Volume: 4 Issue: 1 Pages: 1-4
- DOI
  10.15761/srj.1000163
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10273
[Journal Article] DNA hypermethylation of sirtuin 1 (SIRT1) caused by betal quid chewing　-a possible predictive biomarker for malignant transformation.2020
- Author(s)
  Islam S, Uehara O, Matsuoka H, Kuramitsu Y, Adhikari BR, Hiraki D, Toraya S, Jayawardena A, Saito I, Muthumala M, Nagayasu H, Abiko Y, I Chiba.
- Journal Title
  
  Clinical Epigenetics
  
  Volume: 12 Issue: 1 Pages: 12-12
- DOI
  10.1186/s13148-019-0806-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07218, KAKENHI-PROJECT-17K11916
[Journal Article] A rare case of peripheral odontogenic keratocyst in the buccal space: A case report2019
- Author(s)
  Adhikari BR, Paudel D, Harada F, Morikawa T, Nakayama E, Shimo T, Nagayasu H, Abiko Y
- Journal Title
  
  The Dental Journal of Health Sciences University of Hokkaido
  
  Volume: 38 Pages: 29-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10273
[Journal Article] 導帯管による低位埋伏智歯が疑われた1例2019
- Author(s)
  若林茉梨絵、原田文也、Nagwan Ali Saeed Elsayed、南田康人、石川昌洋、関　姫乃、淀川慎太郎、田代真康、中山英二、志茂　剛、村田　勝、安彦善裕、Berthold H. HELL、永易裕樹
- Journal Title
  
  北海道医療大学歯学雑誌
  
  Volume: 38 Pages: 53-58
- NAID
  120006821073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10273
[Journal Article] クルクミンがアレコリン誘発性マトリックスプロテアーゼに与える影響2019
- Author(s)
  森川哲郎、植原　治、平木大地、虎谷斉子、Puja Neopane、Durga Paudel、原田文也、髙井理衣、吉田光希、永易裕樹、千葉逸朗、安彦善裕
- Journal Title
  
  日本口腔検査学会雑誌
  
  Volume: 11 Pages: 25-30
- NAID
  120006605695
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11916
[Journal Article] Upregulated expression of MMP-9 in gingival epithelial cells induced by prolonged stimulation with arecoline2017
- Author(s)
  Uehara Osamu、Takimoto Kousuke、Morikawa Tetsuro、Harada Fumiya、Takai Rie、Adhikari Bhoj Raj、Itatsu Ryoko、Nakamura Tomohisa、Yoshida Koki、Matsuoka Hirofumi、Nagayasu Hiroki、Saito Ichiro、Muthumala Malsantha、Chiba Itsuo、Abiko Yoshihiro
- Journal Title
  
  Oncology Letters
  
  Volume: 14 Issue: 1 Pages: 1186-1192
- DOI
  10.3892/ol.2017.6194
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11916
[Journal Article] 術後開口訓練に山形大学式歯科用開口器 ( かいくん) を試用した両側筋突起過長症の一例2013
- Author(s)
  金澤　香, 中山英二, 柴田考典, 永易裕樹, 有末　眞, 淀川慎太郎, 飯野光喜
- Journal Title
  
  日顎誌
  
  Volume: 25 Pages: 92-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592937
[Journal Article]2013
- Author(s)
  金澤香,中山英二,柴田考典,永易裕樹,有末眞,淀川慎太郎,飯野光喜
- Journal Title
  
  術後開口訓練に山形大学式歯科用開口器(かいくん^®)を試用した両側筋突起過長症の一例日顎誌
  
  Volume: 25 Pages: 92-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592937
[Journal Article] ,唾液腺腫瘍の画像診断について2011
- Author(s)
  中山英二, 大内知之, 賀来亨, 柴田考典, 有末眞, 永易裕樹, 安彦善裕, 上野繭美, 河津俊幸, 吉浦一紀, 浅香雄一郎, 上田倫弘, 山下徹郎, 仲盛健治, 平塚博義, 針谷靖史, 関口隆
- Journal Title
  
  日本口腔腫瘍学会誌
  
  Volume: 23 Pages: 59-68
- NAID
  10030795939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592937
[Journal Article]2011
- Author(s)
  中山英二,大内知之,賀来亨,柴田考典,有末眞,永易裕樹,安彦善裕,上野繭美,河津俊幸,吉浦一紀,浅香雄一郎,上田倫弘,山下徹郎,仲盛健治,平塚博義,針谷靖史,関口隆
- Journal Title
  
  唾液腺腫瘍の画像診断について口腔腫瘍
  
  Volume: 23 Pages: 59-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592937
[Journal Article] Ameloblastic carcinoma ex ameloblastoma : report of a case-possible involvement of CpG island hypermethylation of the p16 gene in malignant transformation.2007
- Author(s)
  Abiko Y, Nagayasu H, Takeshima M, Yamazaki M, Nishimura M, Kusano K, Kitajo H, Saitoh M, Kawakami T, Chiba I, Kaku T
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103
  
  Pages: 72-76
- Data Source
  KAKENHI-PROJECT-16591894
[Journal Article] Ameloblastic carcinoma ex ameloblastoma : report of a case possible involvement of CpG island hypermethylation of the p16 gene in malignant transformation2007
- Author(s)
  Y.Abiko, H.Nagayasu, M.Takashima, M.Yamazaki, M.Nishimura, K.Kusano, H.Kitajo, M.Saitoh, et al.
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral adiol Endod 103
  
  Pages: 72-76
- Data Source
  KAKENHI-PROJECT-17592100
[Journal Article] 「口腔内科相談外来」と「診療内科・医療心理室」との連携による口腔心身症患者へのアプローチ2007
- Author(s)
  齋藤正人, 安彦善裕, 川上智史, 池田和博, 永易裕樹, 木下憲治, 宮崎友香, 志賀満江, 佐々木直, 坂野雄二
- Journal Title
  
  日本歯科医療管理学会雑誌 41・3
  
  Pages: 175-179
- Data Source
  KAKENHI-PROJECT-17592100
[Journal Article] Ameloblastic carcinoma ex ameloblastoma : report of a case possible involvement of CpG island hypermethylation of the p16 gene in malignant transformation2007
- Author(s)
  Y.Abiko, H.Nagayasu, M.Takeshima, M.Yamazaki, M.Nishimura, K.Kusano, H.Kitajo, M.Saitoh, et al.
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103
  
  Pages: 72-76
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592100
[Journal Article] 「口腔内科相談外来」と「心療内科・医療心理室」との連携による口腔心身症患者へのアプローチ2007
- Author(s)
  齋藤正人, 安彦善裕, 川上智史, 池田和博, 永易裕樹, 木下憲治, 宮崎友香, 志賀満江, 佐々木直, 坂野雄二
- Journal Title
  
  日本歯科医療管理学会雑誌 41・3
  
  Pages: 175-179
- NAID
  10019266767
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592100
[Journal Article] Ameloblastic carcinoma ex ameloblastoma : report of a case possible involvement of CpG island hypermethylation of the p16 gene in malignant transformation2007
- Author(s)
  Y.Abiko, H.Nagayasu, M.Takeshima, M, Yamazaki, M.Nishimura, K.Kusano, H.Kitajo, M.Saitoh, et al.
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103
  
  Pages: 72-76
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17592100
[Journal Article] Management of Oral Psychosomatic Disorders in Oral Medicine Consultatin Clinics in Cooperation with Psychosomatic Medicine and Medical Psychology Clinics2006
- Author(s)
  M.Saitoh, Y.Abiko, T.Kawakami, Y.Ikeda, H.Nagayasu, et al.
- Journal Title
  
  Japanese Journal of Practice Administration 41(3)
  
  Pages: 175-179
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17592100
[Journal Article] Inhibitory effects of fermented brown rice and rice bran on the development of acute hepatitis in Long-evans Cinamon rats2006
- Author(s)
  T.Shibata, H.Nagayasu, H, Kitajyo, M, Arisue, T Yamashita, D.Hatakeyama, T.Iwasaki, H.Kbayashi
- Journal Title
  
  Oncology reports 15
  
  Pages: 869-874
- Data Source
  KAKENHI-PROJECT-17592100
[Presentation] A standardized extract of cultured Lentinula edodes mycelia (AHCC) down-regulated cortactin expression in prostate cancer cells.2023
- Author(s)
  Tanaka Y, Yamashita SN, Kitagawa T, Baron B, Tokuda K, Paudel D, Nakagawa K, Ohta T, Hamada JI, Kobayashi M, Nagayasu H, Kuramitsu Y.
- Organizer
  The 31st Annual Meeting of International Congress on Nutrition and Integrative Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K10229
[Presentation] Inhibition of pancreatic cancer cell migration by AHCC2022
- Author(s)
  Kuhara K, Islam S, Kitagawa T, Shimo T, Nagayasu H, Kuramitsu Y.
- Organizer
  The 30th Annual Meeting of International Congress on Nutrition and Integrative Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K10229
[Presentation] Demethylation effect of 5-Azacytidine on oral squamous cell carcinoma2021
- Author(s)
  Koki Yoshida, Shuhei Takahashi, Fumiya Harada, Dedy Ariwansa, Ariuntsetseg Khurelchuluun, Durga Paudel, Daichi Hiraki, Tetsuro Morikawa, Osamu Uehara, Jun Sato, Yoshihiro Abiko, Hiroki Nagayasu
- Organizer
  第34回日本口腔診断学会、31回日本口腔内科学会合同開催学会
- Data Source
  KAKENHI-PROJECT-21K10121
[Presentation] 口腔扁平上皮癌におけるエピゲノム薬の腫瘍抑制効果の検討2021
- Author(s)
  高橋周平、吉田光希、原田文也、Ariwansa Dedy、Khurelchuluun Ariuntsetseg、Paudel Durga、平木大地、森川哲郎、植原治、佐藤惇、永易裕樹、安彦善裕
- Organizer
  第53回日本臨床分子形態学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-21K10121
[Presentation] ３D造形支援システムを用いて精密再建を行った下顎歯肉癌の1例2021
- Author(s)
  原田文也、平木大地、若林茉梨絵、関　姫乃、南田康人、石川昌洋、佐々木智也、淀川慎太郎、中山英二、志茂　剛、安彦善裕、永易裕樹
- Organizer
  北海道医療大学歯学会第39回学術大会
- Data Source
  KAKENHI-PROJECT-19K10273
[Presentation] Osteoma of the maxillary sinus: A case report2020
- Author(s)
  Ariuntsetseg Khurelchuluun, Durga Paudel, Koki Yoshida, Teysuro Morikawa, Fumiya Harada, Jun Sato, Tomoaki Sano, Eiji Nakayama, Tsuyoshi Shimo, Hiroki Nagayasu, Yoshihiro Abiko
- Organizer
  北海道医療大学歯学会第38回学術大会
- Data Source
  KAKENHI-PROJECT-19K10273
[Presentation] 診断に苦慮した咀嚼筋腱・腱膜過形成症の１例2020
- Author(s)
  Nagwan Ali Saeed Elsayed 、志茂　剛、原田文也、武田成浩、南田康人、若林茉梨絵、佐藤幸平、Karnoon Shamsoon、斎藤隆史、安彦善裕、田代真康、中山英二、川上智史、永易裕樹
- Organizer
  北海道医療大学歯学会第38回学術大会
- Data Source
  KAKENHI-PROJECT-19K10273
[Presentation] 口腔外より摘出した低位埋伏智歯の1例2020
- Author(s)
  久原啓資、原田史也、佐野聖子、南田康人、武田成浩、中山英二、奥村一彦、志茂剛、安彦善裕、永易裕樹
- Organizer
  第46回公益社団法人日本口腔外科学会北日本支部学術集会
- Data Source
  KAKENHI-PROJECT-19K10273
[Presentation] Tooth extraction in a patient with juvenile osteoporosis and cardiovascular disease2020
- Author(s)
  N Karnoon Shamsoon,Tsuyoshi Shimo,Fumiya Harada,Kazuhiro Miyamoto,Tatsuji Odachi,Masahiro Ishikawa,Tomofumi Kawakami,Takashi Saito, Yoshihiro Abiko, Eiji Nakayama, Hiroki Nagayasu
- Organizer
  北海道医療大学歯学会第38回学術大会
- Data Source
  KAKENHI-PROJECT-19K10273
[Presentation] 咀嚼筋腱・腱膜過形成症2例-画像所見の差について2020
- Author(s)
  中山英二、田代真康、南田康人、武田成浩、佐野友昭、杉浦一考、飯嶋雅弘、吉田光希、志茂　剛、永易裕樹
- Organizer
  日本歯科放射線学会第1回秋季学術大会
- Data Source
  KAKENHI-PROJECT-19K10273
[Presentation] 炎症性肉芽を伴う導帯管に関連した下顎低位埋伏智歯の２例2019
- Author(s)
  中山英二、田代真康、若林茉梨絵、原田文也、佐野友昭、杉浦一考、安彦善裕、志茂　剛、永易裕樹
- Organizer
  日本歯科放射線学会第229回関東地方会・第40回北日本地方会・第27回合同地方会
- Data Source
  KAKENHI-PROJECT-19K10273
[Presentation] DNA methylation of sirtuin-1 gene could be a novel biomarker for early prediction of betel quidinduced oral cancer2019
- Author(s)
  Islam Shajedul, Uehara Osamu, Kuramitsu Yasuhiro, Nagayasu Hiroki, Chiba Itsuo
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-17K11916
[Presentation] モデルサージェリーを用いて再建を行ったエナメル上皮腫の1例2019
- Author(s)
  原田文也、武田成浩、Nagwan Ali Saeed Elsayed、若林茉梨絵、関　姫乃、南田康人、石川昌洋、佐々木智也、淀川慎太郎、中山英二、奥村一彦、村田　勝、安彦善裕、志茂　剛、永易裕樹
- Organizer
  第38回日本口腔腫瘍学会総会
- Data Source
  KAKENHI-PROJECT-19K10273
[Presentation] ベテル噛みの口腔粘膜への影響2019
- Author(s)
  原田文也，植原　治，志茂　剛，安彦善裕，永易裕樹
- Organizer
  第73回日本口腔科学会
- Data Source
  KAKENHI-PROJECT-17K11916
[Presentation] 頸部郭清術後に生じた鎖骨骨折の１例2017
- Author(s)
  田代真康、佐野友昭、杉浦一考、瀧本紘佑、西村学子、永易裕樹、安彦善裕、中山英二
- Organizer
  北海道医療大学歯学会第36回学術大会
- Data Source
  KAKENHI-PROJECT-16K11515
[Presentation] 前歯部まで波及した術後性上顎嚢胞における内部性状の画像所見2017
- Author(s)
  中山英二、佐野友昭、草野　薫、松沢史宏、西村学子、杉浦一考、田代真康、安彦善裕、永易裕樹
- Organizer
  日本歯科放射線学会第225回関東地方会・第37回北日本地方会・第25回合同地方会
- Data Source
  KAKENHI-PROJECT-16K11515
[Presentation] 上顎に発生した骨巨細胞腫の一例2013
- Author(s)
  植村太輔、永易裕樹、北所弘行、淀川慎太郎、田崎純一、佐野聖子、鬼頭秀和、安彦善裕、中山英二、柴田考典、有末眞
- Organizer
  北海道医療大学歯学会第31回学術大会
- Place of Presentation
  札幌
- Year and Date
  2013-03-09
- Data Source
  KAKENHI-PROJECT-23592937
[Presentation] 特異的な画像所見を呈した上顎の骨巨細胞腫の一例2013
- Author(s)
  佐藤健彦、田崎純一、淀川慎太郎、北所弘行、永易裕樹、中山英二、安彦善裕、柴田考典、有末眞
- Organizer
  第39回公益社団法人日本口腔外科学会北日本支部学術集会
- Place of Presentation
  盛岡
- Year and Date
  2013-06-28
- Data Source
  KAKENHI-PROJECT-23592937
[Presentation] 術後訓練に山形大学式開口訓練器(シェル型)(かいくん®)を試用した両側筋突起過長症の一例2012
- Author(s)
  金澤香、中山英二、柴田考典、永易裕樹、有末眞、淀川慎太郎
- Organizer
  第25回日本顎関節学会総会・学術大会
- Place of Presentation
  札幌
- Year and Date
  2012-07-14
- Data Source
  KAKENHI-PROJECT-23592937
[Presentation] 内部に高CT値領域が認められた下顎骨病変の２例2012
- Author(s)
  中山英二、草野　薫、鬼頭秀和、安彦善裕、杉浦一考、佐野友昭、大西　隆、永易裕樹、柴田考典、有末　眞
- Organizer
  日本歯科放射線学会第17回臨床画像大会
- Place of Presentation
  盛岡市
- Data Source
  KAKENHI-PROJECT-23592937
[Presentation] 下顎骨中心性神経鞘腫の1例2012
- Author(s)
  鬼頭秀和、吉本良太、中山英二、安彦善裕、永易裕樹、柴田考典、有末眞
- Organizer
  第38回社団法人日本口腔外科学会北日本地方会
- Place of Presentation
  札幌
- Year and Date
  2012-06-23
- Data Source
  KAKENHI-PROJECT-23592937
[Presentation] 下顎骨中心性神経鞘腫の1例2012
- Author(s)
  鬼頭秀和、吉本良太、佐野友昭、中山英二、安彦善裕、永易裕樹、柴田考典、有末眞
- Organizer
  北海道医療大学歯学会第30回学術大会
- Place of Presentation
  札幌
- Year and Date
  2012-03-03
- Data Source
  KAKENHI-PROJECT-23592937
[Presentation] 内部に高CT値領域が認められた下顎骨病変の2例2012
- Author(s)
  中山英二、草野薫、鬼頭秀和、安彦善裕、杉浦一考、佐野友昭、大西隆、永易裕樹、柴田考典、有末眞
- Organizer
  日本歯科放射線学会第17回臨床画像大会
- Place of Presentation
  大阪
- Year and Date
  2012-10-27
- Data Source
  KAKENHI-PROJECT-23592937
[Presentation] 骨形成を伴った上顎洞炎の1例2012
- Author(s)
  淀川慎太郎、植村太輔、北所弘行、佐野聖子、鬼頭秀和、西村学子、有末眞、柴田考典、中山英二、安彦善裕、永易裕樹
- Organizer
  第4回北海道口腔内科研究会
- Place of Presentation
  札幌
- Year and Date
  2012-04-06
- Data Source
  KAKENHI-PROJECT-23592937
[Presentation] 中枢性開口障害を疑わせた1例2011
- Author(s)
  柴田考典、淀川慎太郎、中山英二、永易裕樹、有末眞
- Organizer
  第24回日本顎関節学会
- Place of Presentation
  広島
- Year and Date
  2011-07-23
- Data Source
  KAKENHI-PROJECT-23592937

1. SHIBATA Toshiyuki (50226172)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
2. ARISUE Makoto (20091407)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
3. ABIKO Yoshihiro (90260819)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
4. KITAJYO Hiroyuki (00347775)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
5. NAKAYAMA Eiji (60172467)

# of Collaborated Projects: 3 results

# of Collaborated Products: 33 results
6. SANO Tomoaki (20244866)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
7. SUGIURA Kazutaka (90529398)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
8. KAWANO Takashi (00285537)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 田代真康 (20758338)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
10. 植原治 (00709248)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
11. 志茂剛 (40362991)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
12. KOBAYASHI Masanobu (80241321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. OHNISHI Takashi (10183237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. YOSHIMOTO Ryota (10364259)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. KATO Yukihiro (30293567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TOIDA Makoto (90313890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. YAMASHITA Tomomi (80345793)

# of Collaborated Projects: 1 results

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18. KAKU Tohru (60133253)

# of Collaborated Projects: 1 results

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19. ARAKAWA Toshiya (40306254)

# of Collaborated Projects: 1 results

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20. OKUMURA Kazuhiko (60194510)

# of Collaborated Projects: 1 results

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21. 遠藤一彦 (70168821)

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22. 高井理衣 (50781085)

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23. 根津尚史 (40264056)

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24. 吉田光希 (30453260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
25. 原田文也 (30824205)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
26. 藏滿保宏 (50281811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 良沢昭銘 (60363123)

# of Collaborated Projects: 1 results

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28. 堀江尚弘 (30802318)

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29. 北川孝雄 (20614928)

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30. 星和人 (30344451)

# of Collaborated Projects: 1 results

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31. 江草宏 (30379078)

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32. 疋田温彦 (60443397)

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33. 蔵満保宏

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# of Collaborated Products: 4 results

NAGAYASU HIROKI 永易 裕樹

NAGAYASU Hiroki 永易 裕樹

永易 裕樹 ナガヤス ヒロキ

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薬剤耐性口腔扁平上皮癌に対するドライバー遺伝子変異を標的とした治療法の開発Principal Investigator

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Comprehensive analysis of epigenomic aberrant genes in oral cancer and verification of tumor suppressive effect by epigenomic drugs.Principal Investigator

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Elucidation of the carcinogenic mechanism for the prevention of oral cancer caused by betel quid chewingPrincipal Investigator

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Study of the inhibitory effects on malignant progression and anticancer drug sensitivity of human squamous cell carcinoma by intensifying cell to cell communicationPrincipal Investigator

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Study of the effects of epidermal growth factor on genomic instability and malignant phenotype of oral squamous cell carcinoma cellsPrincipal Investigator

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Study of the inhibitory effects on invasion and metastasis of human squamous cell carcinoma by intensifying endothelial cell to cell adhesionPrincipal Investigator

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NAGAYASU HIROKI 永易裕樹

NAGAYASU Hiroki 永易裕樹

永易裕樹ナガヤスヒロキ

[Journal Article] DNA hypermethylation of sirtuin 1 (SIRT1) caused by betal quid chewing　-a possible predictive biomarker for malignant transformation.2020