Sekiguchi Fumiko 関口富美子

… Alternative Names

SEKIGUCHI Fumiko 関口富美子

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Researcher Number	90271410
Other IDs
Affiliation (Current)	2025: 近畿大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2008 – 2024: Kinki University, 薬学部, 准教授 2006 – 2007: 近畿大学, 薬学部, 講師 2005: 薬学部, 講師 2005: 近畿大, 薬学部, 講師 2004: 近畿大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Pharmacology in pharmacy / Biological pharmacy / Basic Section 48030:Pharmacology-related / Basic Section 47040:Pharmacology-related / General pharmacology Except Principal Investigator Basic Section 47040:Pharmacology-related / Pain science / General pharmacology / 疼痛学
Keywords	Principal Investigator トロンビン / HMGB1 / 神経障害性疼痛 / T型カルシウムチャネル / 硫化水素合成酵素 / 細胞・組織 / 血液凝固系因子 / ＨＭＧＢ１ / 血液凝固因子 / シュワン細胞 … More / D-カルビドパ / 抗がん剤抵抗性獲得 / 化学療法誘起末梢神経障害 / cystathionine-β-synthase / CBS阻害薬 / がん増殖抑制 / カルビドパ / 芳香族L-アミノ酸脱炭酸酵素阻害薬 / 多発性骨髄腫 / シスタチオニン-β-シンターゼ（CBS） / 神経再生 / Angiopoietin-1 / トロンボモジュリン / angiopoiethin-1 / 神経損傷 / RAGE / thrombin / thrombomodulin / 神経突起伸長 / Cav3.2 T型Ca2+チャネル / 後根神経節 / Cav3.2 T型カルシウムチャネル / 一次知覚神経 / USP5 / Egr-1 / シグナル伝達 / 酵素 / アポトーシス / 細胞増殖 / 胃粘膜傷害 / 抗アポトーシス因子 / 胃癌細胞増殖 / 炎症 / ヘリコバクター・ピロリ / Proteinase-activated receptor / 癌 / 細菌 / 感染症 / 受容体発現 / 薬理学 / PAR-2-knockout mouse / Apamin-sensitive K^+ channels / Relaxation / Contraction / Gastrointestinal smooth muscle / Intestine / Stomach / Proteinase (protease)-activated receptor (PAR) … More Except Principal Investigator 痛み / トロンボモジュリン / HMGB1 / 神経障害性疼痛 / 化学療法誘発性末梢神経障害 / 内臓痛 / カルシウムチャネル / 硫化水素 / 難治性疼痛 / 血小板 / 内蔵痛 / マクロファージ / 抗血小板薬 / 血液凝固 / 過敏性腸症候群 / 糖尿病性末梢神経障害 / 結腸過敏 / トロンビン / 抗凝固薬 / inflammation / redox / calcium channel / sensory nerve / messenger / gas / pain / hydrogen sulfide / 炎症 / 還元 / 知覚神経 / メッセンジャー / ガス / 結腸痛 / 神経症障害性疼痛 / TLR4 / 膀胱痛 / ＨＭＧＢ１ / 膵臓痛 / Toll-like receptor 4 / CXCR4 / RAGE / 疼痛制御 / プロテインキナーゼA / カルシウム / イオンチャネル / 神経突起 / PKA / 薬理学 / 神経突起伸長 / カルシニューリン / ＰＫＡ / T型Ca^<2+>チャネル / siRNA / 神経因性疼痛 / T型カルシウムチャネル / 生体内ガス / ニューロパチー Less

巨核球・血小板系由来HMGB1の各種難治性疼痛への関与
- Principal Investigator
  
  川畑篤史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kindai University
The role of change in expression levels of coagulation factors in Schwann cells in the neuropathic painPrincipal Investigator
- Principal Investigator
  
  関口富美子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kindai University
Study on pain modulation by the interaction of coagulation factors with HMGB1 and its clinical relevance
- Principal Investigator
  
  Kawabata Atsufumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kindai University
Possibility for increase in efficacy and alleviation in adverse effect of anti-cancer drugs by inhibition of endogenous hydrogen sulfide synthesisPrincipal Investigator
- Principal Investigator
  
  SEKIGUCHI Fumiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kindai University
Roles of HMGB1, a nuclear protein, in axonal regeneration after nerve injuryPrincipal Investigator
- Principal Investigator
  
  Sekiguchi Fumiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kindai University
Roles of T-type calcium channels and calcineurin in inflammatory or neuropathic painPrincipal Investigator
- Principal Investigator
  
  SEKIGUCHI Fumiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kindai University
Prevention and treatment of chemotherapy-induced neuropathic pain and visceral pain by targeting HMBG1, a nuclear protein
- Principal Investigator
  
  KAWABATA Atsufumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Kindai University
Study of roles of endogenous hydrogen sulfide in stomach with mucosal injuryPrincipal Investigator
- Principal Investigator
  
  SEKIGUCHI Fumiko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kinki University
Pain regulation by PKA and calcineurin through functional modulation of T-type calcium channels
- Principal Investigator
  
  KAWABATA Atsufumi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Kinki University
Study on effects of Helicobacter pylori infection on expression and function of proteinase-activated receptors in gastric mucosal epithelium.Principal Investigator
- Principal Investigator
  
  SEKIGUCHI Fumiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kinki University
Involvement of the gasotransmitter hydrogen sulfide in neurogenic pain
- Principal Investigator
  
  KAWABATA Atsufumi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  疼痛学
- Research Institution
  Kinki University
Roles for hydrogen sulfide, a novel endogenous gasotransmitter, in nociceptive processing
- Principal Investigator
  
  KAWABATA Atsufumi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kinki University
G蛋白共役型プロテアーゼ受容体による消化管運動調節メカニズムの解析Principal Investigator
- Principal Investigator
  
  関口富美子
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kinki University

[Journal Article] Opioid modulation of T-type Ca^<2+> channel-dependent neuritogenesis/neurite outgrowth through the prostaglandin E_2EP_4 receptor/proteinkinase A pathway in mouse dorsal root ganglion neurons2023
- Author(s)
  Takashi Maeda, Fumiko Sekiguchi, Kenji Mitani, Ryosuke Yamagata, Maho Tsubota, Shigeru Yoshida, Atsufumi Kawabata
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 639 Pages: 142-149
- DOI
  10.1016/j.bbrc.2022.11.108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08325
[Journal Article] Development of hepatic impairment aggravates chemotherapy-induced peripheral neuropathy following oxaliplatin treatment: Evidence from clinical and preclinical studies2022
- Author(s)
  Miyamoto Tomoyoshi、Domoto Risa、Sekiguchi Fumiko、Kamaguchi Riki、Nishimura Rika、Matsuno Misato、Tsubota Maho、Fujitani Masanori、Hatanaka Shigekatsu、Koizumi Yuichi、Wang Dengli、Nishibori Masahiro、Kawabata Atsufumi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 148 Issue: 3 Pages: 315-325
- DOI
  10.1016/j.jphs.2022.01.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06608
[Journal Article] Role of neuron-derived ATP in paclitaxel-induced HMGB1 release from macrophages and peripheral neuropathy2022
- Author(s)
  Domoto Risa、Sekiguchi Fumiko、Kamaguchi Riki、Iemura Maiko、Yamanishi Hiroki、Tsubota Maho、Wang Dengli、Nishibori Masahiro、Kawabata Atsufumi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 148 Issue: 1 Pages: 156-161
- DOI
  10.1016/j.jphs.2021.11.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-21K06608
[Journal Article] Caspase-Dependent HMGB1 Release from Macrophages Participates in Peripheral Neuropathy Caused by Bortezomib, a Proteasome-Inhibiting Chemotherapeutic Agent, in Mice2021
- Author(s)
  Tsubota Maho、Miyazaki Takaya、Ikeda Yuya、Hayashi Yusuke、Aokiba Yui、Tomita Shiori、Sekiguchi Fumiko、Wang Dengli、Nishibori Masahiro、Kawabata Atsufumi
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 10 Pages: 2550-2550
- DOI
  10.3390/cells10102550
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-21K06608
[Journal Article] Peripheral HMGB1-induced hyperalgesia in mice: redox state-dependent distinct roles of RAGE and TLR42016
- Author(s)
  Yamasoba, D., Tsubota, M., Domoto, R., Sekiguchi, F., Nishikawa, H., Liu, K., Nishibori, M., Ishikura, H., Yamamoto, T., Taga, A., Kawabata, A.
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 130 Issue: 2 Pages: 139-142
- DOI
  10.1016/j.jphs.2016.01.005
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460710, KAKENHI-PROJECT-16K08909
[Journal Article] Endogenous Hydrogen Sulfide Enhances Cell Proliferation of Human Gastric Cancer AGS Cells2016
- Author(s)
  Fumiko Sekiguchi, Teruki Sekimoto, Ayaka Ogura and Atsufumi Kawabata
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 39 Issue: 5 Pages: 887-890
- DOI
  10.1248/bpb.b15-01015
- NAID
  130005149260
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590122
[Journal Article] Involvement of high mobility group box 1 in the development and maintenance of chemotherapy-induced peripheral neuropathy in rats2016
- Author(s)
  Nishida, T., Tsubota, M., Kawaishi, Y., Yamanishi, H., Kawakami, N., Sekiguchi, F., Ishikura, H., Liu, K., Nishibori, M., Kawabata, A.
- Journal Title
  
  Toxocology
  
  Volume: 365 Pages: 48-58
- DOI
  10.1016/j.tox.2016.07.016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460710, KAKENHI-PROJECT-16K08909
[Journal Article] Therapeutic potential of RQ-00311651, a novel T-type Ca2+ channel blocker, in distinct rodent models for neuropathic and visceral pain.2016
- Author(s)
  Sekiguchi F, Kawara Y, Tsubota M, Kawakami E, Ozaki T, Kawaishi Y, Tomita S, Kanaoka D, Yoshida S, Ohkubo T, Kawabata A.
- Journal Title
  
  Pain
  
  Volume: 157 Issue: 8 Pages: 1655-1665
- DOI
  10.1097/j.pain.0000000000000565
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460112
[Journal Article] AKAP-dependent sensitization of Cav3.2 channels via the EP4 receptor/cyclic AMP pathway mediates prostaglandin E2-induced mechanical hyperalgesia.2013
- Author(s)
  Sekiguchi, F., Matsumoto, Y., Maeda, Y., Tsubota-Matsunami, M., Nishikawa, H. and Kawabata, A.
- Journal Title
  
  Br. J. Pharmacol.
  
  Volume: 168 Issue: 3 Pages: 734-745
- DOI
  10.1111/j.1476-5381.2012.02174.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590729
[Journal Article] T-type Calcium Channels: Functional Regulation and Implication in Pain Signaling2013
- Author(s)
  Sekiguchi, F., Kawabata, A.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 122 Issue: 4 Pages: 244-250
- DOI
  10.1254/jphs.13R05CP
- NAID
  10031196197
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590729
[Journal Article] Endogenous hydrogen sulfide contributes to cell proliferation in gastric cancer cells2012
- Author(s)
  Fumiko Sekiguchi, Teruki Sekimoto, Atsufumi Kawabata
- Journal Title
  
  J Pharmacol. Sci
  
  Volume: vol. 118 (Suppl. 1) Pages: 122-122
- Data Source
  KAKENHI-PROJECT-23590122
[Journal Article] Biological activity of Helicobacter pylori components in mammalian cells : is it independent of proteinase-activated receptors?2012
- Author(s)
  SEKIGUCHI, F, MATSUMOTO, Y, MAEDA, Y, TSUBOTA-MATSUNAMI, M, NISHIKAWA, H, and KAWABATA, A.
- Journal Title
  
  Journal of Physiology and Pharmacology.
  
  Volume: 63 Pages: 571-576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590097
[Journal Article] Upregulation of Ca_v3.2 T-type calcium channels targeted by endogenous hydrogen sulfide contributes to maintenance of neuropathic pain2010
- Author(s)
  Takahashi T., Aoki T., Okubo K., Maeda Y., Sekiguchi F., Mitani K., Nishikawa H., Kawabata A.
- Journal Title
  
  Pain Vol.150
  
  Pages: 183-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20602016
[Journal Article] Hyperalgesia induced by spinal and peripheral hydrogen sulfide: Evidence for involvement of Cav3.2 T-type calcium channels2009
- Author(s)
  Maeda Y., Aoki Y., Sekiguchi F., Matsunami M., Takahashi T., Nishikawa H., Kawabata A.
- Journal Title
  
  Pain Vol.142
  
  Pages: 127-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20602016
[Journal Article] Hydrogen sulfide as a novel nociceptive messenger2007
- Author(s)
  Kawabata, A., Ishiki, T., Nagasawa, K., Yoshida, H., Maeda, Y., Takahashi, T., Sekiguchi, F., Wada, T., Ichida, S., Nishikawa, H.
- Journal Title
  
  Pain 132
  
  Pages: 74-81
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590233
[Presentation] Chemotherapy-induced peripheral neuropathy caused by vincristine involves high mobility group box 1 (HMGB1) released from macrophages and Schwann cells2024
- Author(s)
  Fumiko Sekiguchi, Yui Aokiba, Kenta Yatsu, Momoko Sako, Maho Tsubota, Yasuko Tomono, Masahiro Nishibori, Atsufumi Kawabata
- Organizer
  FENS Forum 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06372
[Presentation] 抗がん剤vincristine誘起末梢神経障害の発現におけるマクロファージおよびSchwann細胞由来HMGB1と局所血液凝固系の相反する役割2024
- Author(s)
  迫桃子，青木葉優衣，谷津健太，関口富美子，坪田真帆，Wang Dengli，西堀正洋，川畑篤史
- Organizer
  第144回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K06608
[Presentation] 抗がん剤vincristine誘起末梢神経障害の発現におけるマクロファージおよびSchwann細胞由来HMGB1と局所血液凝固系の相反する役割2024
- Author(s)
  迫　桃子、青木葉優衣、谷津健太、関口富美子、坪田真帆、友野靖子、西堀正洋、川畑篤史
- Organizer
  第144回　日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-23K06372
[Presentation] プチン受容体遺伝子欠損および高脂肪食摂取による2型糖尿病モデルマウスの有痛性末梢神経障害へのHMGB1とアナフィラトキシンC5aの関与について2024
- Author(s)
  佐久間海地、中野遥、岩根詩織、坪田真帆、関口富美子、友野靖子、西堀正洋、川畑篤史
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06608
[Presentation] 遺伝性および高脂肪食摂取による2型糖尿病モデルマウスにおける有痛性末梢神経障害に対するthrombomodulin alfa の抑制効果：HMGB1と補体C5aの不活性化が関与する可能性について2023
- Author(s)
  佐久間海地、中野遥、大東麻哉、岩根詩織、坪田真帆、関口富美子、友野靖子、西堀正洋、川畑篤史
- Organizer
  第73回日本薬学会関西支部大会
- Data Source
  KAKENHI-PROJECT-21K06608
[Presentation] 過敏性腸症候群モデルマウスの結腸過敏に関与するHMGB1の由来細胞の同定とRAGE拮抗薬azeliragonおよび関節炎・腸炎治療薬sulfasalazineを用いた予防的介入2023
- Author(s)
  坪田真帆、佐々木花菜、Shin Eunkyung、岡村悠太、堂本莉紗、関口富美子、岡田卓哉、豊岡尚樹、友野靖子、西堀正洋、川畑篤史
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06608
[Presentation] Butyrate誘起結腸過敏へのマクロファージおよび腸グリア細胞由来HMGB1の関与とRAGE拮抗薬azeliragonおよびリウマチ・炎症性腸疾患治療薬sulfasalazineの効果2023
- Author(s)
  坪田真帆、佐々木花菜、Shin Eunkyung、岡村悠太、堂本莉紗、関口富美子、岡田卓哉、豊岡尚樹、川畑篤史
- Organizer
  第143回日本薬理学会近畿部会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06608
[Presentation] 抗血小板薬はオキサリプラチン誘起末梢神経障害（OIPN）を抑制する：OIPN発症における血小板由来HMGB1の役割2023
- Author(s)
  岸本彩野、堂本莉紗、関千咲斗、松永浩明、松本亜紗菜、坪田真帆、関口富美子、友野靖子、西堀正洋、川畑篤史
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06608
[Presentation] Thrombomodulin/thrombin系で産生されるTAFIa/carboxypeptidase Bは補体成分C5aを不活性化することでoxaliplatin誘発性末梢神経障害を抑制する2022
- Author(s)
  圓尾賢悟、坪田真帆、田島和樹、関口富美子、西堀正洋、南　達郎、伊藤彰敏、川畑篤史
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06608
[Presentation] 内因性H2S産生阻害による多発性骨髄腫細胞の生存抑制: カルビドパとベンセラジドのcystathionine-β-synthase阻害活性とボルテゾミブ耐性多発性骨髄腫治療への応用について2022
- Author(s)
  関口富美子，森口晴香，福島志歩，井場祐里子，坪田真帆，平本志於里，岡田卓哉，豊岡尚樹，田中宏和，芦田隆司，松村到，川畑篤史
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07079
[Presentation] Oxaliplatin誘起末梢神経障害には血小板由来HMGB1が関与する2022
- Author(s)
  岸本彩野、堂本莉紗、松永浩明、松本亜紗菜、坪田真帆、関口富美子、王登莉、西堀正洋、川畑篤史
- Organizer
  第141回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K06608
[Presentation] オキサリプラチン誘起末梢神経障害（OIPN）への血小板由来HMGB1の関与：抗血小板薬のOIPN予防効果について2022
- Author(s)
  岸本彩野、堂本莉紗、松永浩明、松本亜紗菜、坪田真帆、関口富美子、王登莉、西堀正洋、川畑篤史
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06608
[Presentation] 芳香族Lアミノ酸脱炭酸酵素阻害薬カルビドパとベンセラジドは多発性骨髄腫細胞の生存・増殖を抑制する：H2S産生阻害作用の関与について2021
- Author(s)
  森口晴香、関口富美子、福島志歩、本夛泉侑、井場祐里子、坪田真帆、平本志於里、田中宏和、芦田隆司、松村到、川畑篤史
- Organizer
  第71回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-20K07079
[Presentation] 坐骨神経損傷マウスから摘出した後根神経節神経細胞の突起伸長促進にはマクロファージ由来HMGB1が関与する2021
- Author(s)
  関口富美子, 中武ゆい, 坪田真帆、西堀正洋、川畑篤史
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K08325
[Presentation] H2S産生酵素cystathionine-β-synthaseの阻害薬はボルテゾミブ耐性を獲得した多発性骨髄腫細胞の生存・増殖を抑制する2021
- Author(s)
  関口富美子、福島志歩、森口晴香、平本志於里、田中宏和、芦田隆司、松村到、川畑篤史
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20K07079
[Presentation] Thrombomodulin alfaのoxaliplatin誘発性末梢神経障害抑制作用発現におけるHMGB1不活性化とprotein C及びTAFI活性化の相対的重要性と下流シグナル分子の解析2021
- Author(s)
  圓尾賢悟、坪田真帆、田島和樹、関口富美子、西堀正洋、南　達郎、伊藤彰敏、川畑篤史
- Organizer
  第140回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K06608
[Presentation] Effect of extracellular HMGB1 on neuritogenesis in mouse dorsal root ganglion neurons and its inhibition by thrombomodulin alfa.2018
- Author(s)
  Nakatake, Y., Sekiguchi, F., Tsubota, M., Tsujita, R., Honda, G., Kawabata, A.
- Organizer
  11th FENS Forum of Neuroscience. 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08325
[Presentation] Effect of extracellular HMGB1 on neuritogenesis in mouse dorsal root ganglion neurons and its inhibition by thrombomodulin alfa.2018
- Author(s)
  Nakatake, Y., Sekiguchi, F., Tsubota, M., Tsujita, R., Honda, G., Kawabata, A.
- Organizer
  11th FENS Forum of Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08325
[Presentation] HMGB1-induced neurite outgrowth in mouse dorsal root ganglion neurons and its inhibition by thrombomodulin.2017
- Author(s)
  Nakatake, Y., Sekiguchi, F., Tsubota, M., Tsujita, R., Honda, G., Kawabata, A.
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08325
[Presentation] 抗がん薬ボルテゾミブにより誘起される神経障害性疼痛にはCav3.2 T型カルシムチャネルの発現増加が関与する．2017
- Author(s)
  冨田詩織、出口智代、関口富美子、坪田真帆、川畑篤史
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460112
[Presentation] マウス脊髄後根神経節細胞におけるHMGB1誘起神経突起伸長とそれに対する遺伝子組み換えヒト可溶性thrombomodulinの効果2017
- Author(s)
  中武ゆい、関口富美子、坪田真帆、辻田隆一、本田剛一、川畑篤史．
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-17K08325
[Presentation] マウス後根神経節細胞においてthrombomodulin alfaは還元型HMGB1により誘起される神経突起伸長をトロンビン依存的および非依存的に抑制する2017
- Author(s)
  中武ゆい、関口富美子、坪田真帆、辻田隆一、本田剛一、川畑篤史
- Organizer
  生体機能と創薬シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17K08325
[Presentation] マウスの坐骨神経部分結紮誘起神経障害性疼痛には知覚神経におけるCav3.2 T型カルシウムチャネルの発現増加が関与する：転写因子Egr-1および脱ユビキチン化酵素USP5の役割2016
- Author(s)
  式見仕勇、冨田詩織、関口富美子、坪田真帆、岸岡史郎、川畑篤史
- Organizer
  第66回日本薬学会近畿支部総会・大会
- Place of Presentation
  摂南大学薬学部（高槻市）
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-26460112
[Presentation] High mobility group box 1 mediates pancreatic pain in mice2016
- Author(s)
  Kawabata, A., Irie, Y., Tsubota, M., Sekiguchi, F., Ishikura, H., Nishibori, M.
- Organizer
  Physiology 2016
- Place of Presentation
  Convention Centre Dublin（ダブリン）
- Year and Date
  2016-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460710
[Presentation] Molecular mechanisms for the upregulation of Cav3.2 T-type calcium channels in the neuropathic pain.2016
- Author(s)
  Tomita, S., Sekiguchi, F., Tsubota, M., Kawabata, A.
- Organizer
  The 12th International Conference on Protein Phosphatase
- Place of Presentation
  近畿大学（東大阪市）
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460112
[Presentation] ラットあるいはマウスの神経障害性疼痛に関与する一次知覚神経におけるCav3.2 T型Ca2+チャネルの発現誘導メカニズム2016
- Author(s)
  冨田詩織，式見志勇，関口富美子，坪田真帆，川畑篤史
- Organizer
  44)第38回日本疼痛学会
- Place of Presentation
  北海道立道民活動センターかでる2・7（札幌市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-26460112
[Presentation] 第5腰神経切断誘起神経障害性疼痛ラットの後根神経節におけるCav3.2の発現量増加機序の解析：転写促進因子Egr-1による発現誘導と脱ユビキチン化酵素USP5によるプロテアソーム分解抑制2015
- Author(s)
  冨田詩織、関口富美子、坪田真帆、川畑篤史
- Organizer
  次世代を担う創薬・医療薬理シンポジウム 2015
- Place of Presentation
  東京大学薬学部（東京）
- Year and Date
  2015-08-29
- Data Source
  KAKENHI-PROJECT-26460112
[Presentation] Molecular mechanisms for the upregulation of Cav3.2 T-type calcium channels in the dorsal root ganglion of rats with spinal nerve injury-induced neuropathy: involvement of Egr-1 and USP5.2015
- Author(s)
  Tomita, S., Sekiguchi, F., Tsubota, M., Kawabata, A.
- Organizer
  Neuroscience 2015
- Place of Presentation
  McCormick Place (Chicago, IL)
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460112
[Presentation] ラット第5腰神経切断により誘起される神経障害性疼痛および脊髄後根神経節におけるCav3.2 T型Ca2+チャネル発現増加への転写調節因子Egr-1と脱ユビキチン化酵素USP5の関与2015
- Author(s)
  冨田詩織、関口富美子、坪田真帆、川畑篤史
- Organizer
  生体機能と創薬シンポジウム2015
- Place of Presentation
  日本大学薬学部（船橋）
- Year and Date
  2015-08-27
- Data Source
  KAKENHI-PROJECT-26460112
[Presentation] Macrophage-derived high mobility group box 1 participates in the development and maintenance of pancreatic pain through the activation of RAGE and CXCR4 in mice with cerulein-induced acute pancreatitis.2015
- Author(s)
  Irie, Y., Tsubota, M., Sekiguchi, F., Ishikura, H., Nishibori, M., Kawabata, A.
- Organizer
  Neuroscience 2015
- Place of Presentation
  シカゴ、アメリカ
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460710
[Presentation] Bladder pain accompanying cyclophosphamide-induced mouse cystitis involves HMGB1 release upstream of the cystathionine-gamma-lyase/H2S/Cav3.2 pathway in the bladder tissue2015
- Author(s)
  Kawabata, A., Tsubota, M., Yamaguchi, K., Hiramoto, S., Sekiguchi, F., Tanaka, J., Ishikura, H., Nishibori, M.
- Organizer
  Neuroscience 2015
- Place of Presentation
  シカゴ、アメリカ
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460710
[Presentation] カルシニューリン阻害薬タクロリムスはカプサイシン誘起結腸痛を増強する2014
- Author(s)
  寺田侑加, 坪田真帆, 関口富美子, 和田恭一, 桒原健, 髙田充隆, 川畑篤史
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] カルシニューリン阻害薬タクロリムスはカプサイシン誘起結腸痛を増強する2014
- Author(s)
  寺田侑加, 坪田真帆, 関口富美子, 和田恭一, 桒原　健, 髙田充隆, 川畑篤史
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター、仙台
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] ヒト胃癌由来AGS細胞における内因性硫化水素の細胞増殖への関与とその下流シグナルの解析2014
- Author(s)
  小椋彩加、関本晃己、関口富美子、川畑篤史
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山(ポスター発表)
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-23590122
[Presentation] ヒト胃癌由来AGS細胞における内因性硫化水素の細胞増殖への関与とその下流シグナルの解析2014
- Author(s)
  小椋彩加、関本晃己、関口富美子、川畑篤史
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター（岡山市）
- Data Source
  KAKENHI-PROJECT-23590122
[Presentation] 第5腰神経切断神経障害性疼痛ラットにおけるCav3.2 T型Ca2+チャネル発現増加機序の解析：転写調節因子Egr-1と脱ユビキチン化酵素USP5の挙動について2014
- Author(s)
  冨田詩織、関口富美子、坪田真帆、川畑篤史
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県JAビル（和歌山市）
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-26460112
[Presentation] NG108-15細胞におけるdibutyryl cyclic AMP誘起神経分化への内因性硫化水素とCa_v3.2 T型Ca^<2+>チャネルの関与2013
- Author(s)
  竹田優希, 金岡大樹, 関口富美子, 吉田繁, 川畑篤史
- Organizer
  生体機能と創薬シンポジウム2013
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] マウスにおいてprostaglandin E2により誘起されるT型Ca^<2+>チャネルを介する機械的痛覚過敏の特徴:EP2/PKA経路における足場タンパクAKAP150の重要性とEP1/PKC経路の関与について2013
- Author(s)
  竹中秀, 中村早織, 坪田真帆, 関口富美子, 川畑篤史
- Organizer
  第124回日本薬理学会近畿部会
- Place of Presentation
  京都
- Year and Date
  2013-11-01
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] NG108-15細胞におけるdibutyryl cyclic AMP誘起神経分化への内因性硫化水素とCav3.2 T型Ca2+チャネルの関与2013
- Author(s)
  竹田優希、金岡大樹、関口富美子、吉田繁、川畑篤史
- Organizer
  生体機能と創薬シンポジウム2013
- Place of Presentation
  九州大学病院キャンパス、福岡
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] NG108-15細胞のcyclic AMPを介した神経分化への内因性硫化水素の役割2012
- Author(s)
  金岡大樹, 竹田優希, 関口富美子, 吉田繁, 川畑篤史
- Organizer
  第121回日本薬理学会近畿部会
- Place of Presentation
  徳島
- Year and Date
  2012-06-29
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] Roles of endogenous hydrogen sulfide in prolife- ration of gastric cancer cells2012
- Author(s)
  Fumiko Sekiguchi, Teruki Sekimoto, Ayaka Ogura, Atsufumi Kawabata
- Organizer
  7th International Symposium on Cell/Tissue Injury and Cyotoprotection/Organo- protection
- Place of Presentation
  Honolulu(口頭発表)
- Data Source
  KAKENHI-PROJECT-23590122
[Presentation] 知覚神経細胞におけるcyclic AMP誘起神経突起伸長に対するT型Ca^<2+>チャネルおよびK^+チャネルの関与2012
- Author(s)
  前田貴史, 山縣亮介, 三谷健治, 田中友香里, 関口富美子, 川畑篤史
- Organizer
  第122回日本薬理学会近畿部会
- Place of Presentation
  豊中
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] Prostaglandin E_2-induced sensitization of T-type Ca^<2+> channels : a mechanism for mechanical hyperalgesia2012
- Author(s)
  Kanaoka, D., Sekiguchi, F., Nakagawa, M., Aoki Y., Nishimoto Y., Yoshida, S., Tsubota-Matsunami, M, Kawabata, A
- Organizer
  A Satellite Symposium of IUPHAR-GI Section, International Ulcer Week 2012
- Place of Presentation
  東京
- Year and Date
  2012-07-12
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] Roles of endogenous hydrogen sulfide in proliferation of gastric cancer cells2012
- Author(s)
  Sekiguchi, F., Sekimoto, T., Ogura, A., Kawabata, A.
- Organizer
  7th International Symposium on Cell/Tissue Injury and Cyotoprotection/Organoprotection
- Place of Presentation
  Honolulu, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-23590122
[Presentation] 胃癌細胞において内因性に産生される硫化水素は癌細胞増殖に関与する2012
- Author(s)
  関口富美子、関本晃己、川畑篤史
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都(口頭発表)
- Data Source
  KAKENHI-PROJECT-23590122
[Presentation] NG108-15細胞とラット後根神経節細胞におけるCa_v3.2 T型Ca^<2+>チャネル機能のcyclic AMP依存性増強メカニズムの解析2012
- Author(s)
  金岡大樹, 山中瑠美, 関口富美子, 吉田繁, 川畑篤史
- Organizer
  第122回日本薬理学会近畿部会
- Place of Presentation
  豊中
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] マウス脊髄後根神経節培養細胞のプロスタグランジンE_2/cyclic AMP系を介する神経突起伸長におけるT型Ca^<2+>チャネルおよびK^+チャネルの役割2012
- Author(s)
  山縣亮介, 前田貴史, 三谷健治, 関口富美子, 川畑篤史
- Organizer
  生体機能と創薬シンポジウム2012
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] 胃癌細胞における内因性硫化水素の細胞増殖促進作用について2012
- Author(s)
  関本晃己、関口富美子、川畑篤史
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌(ポスター発表)
- Data Source
  KAKENHI-PROJECT-23590122
[Presentation] Roles of endogenous hydrogen sulfide in the cyclic AMP-induced neuronal differentiation in NG108-15 cells2012
- Author(s)
  Kanaoka, D., Takeda, Y., Sekiguchi, F., Yoshida, S., Kawabata, A.
- Organizer
  Neuroscience 2012
- Place of Presentation
  Morial Convention Center (アメリカ・ニューオリンズ)
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] Roles of endogenous hydrogen sulfide in the cyclic AMP-induced neuronal differentiation in NG108-15 cells2012
- Author(s)
  Kanaoka, D., Takeda, Y., Sekiguchi, F., Yoshida, S., Kawabata, A
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] Molecular mechanisms for the neurite outgrowth caused by prostaglandin E2 in mouse dorsal root ganglion cells.2012
- Author(s)
  Maeda, T., Mitani, K., Yamagata, R., Sekiguchi, F., Kawabata, A.
- Organizer
  Neuroscience 2012
- Place of Presentation
  Morial Convention Center (アメリカ・ニューオリンズ)
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] マウス脊髄後根神経節培養細胞のプロスタグランジンE2/cyclic AMP系を介する神経突起伸長におけるT型Ca2+チャネルおよびK+チャネルの役割2012
- Author(s)
  山縣亮介，前田貴史，三谷健治，関口富美子，川畑篤史
- Organizer
  生体機能と創薬シンポジウム2012
- Place of Presentation
  神戸学院大学（兵庫県）
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] Molecular mechanisms for the neurite outgrowth caused by prostaglandin E_2 in mouse dorsal root ganglion cells2012
- Author(s)
  Maeda, T., Mitani, K., Yamagata, R., Sekiguchi, F., Kawabata, A
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] PGE2誘起機械的痛覚過敏にはEP4受容体／PKA系によるCav3.2 T型Ca2+チャネルのAKAP依存性リン酸化が寄与する2011
- Author(s)
  関口富美子、松波真帆、川畑篤史
- Organizer
  第33回日本疼痛学会
- Place of Presentation
  愛媛県県民文化会館（松山）
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] PGE_2誘起機械的痛覚過敏にはEP4受容体/PKA系によるCa_v3.2 T型Ca^<2+>チャネルのAKAP依存性リン酸化が寄与する2011
- Author(s)
  関口富美子, 松波真帆, 川畑篤史
- Organizer
  第33回日本疼痛学会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] Sensitization of T-type calcium channels by prostaglandin E2 via the EP4 receptor/cyclic AMP/protein kinase A pathway: a possible mechanism for mechanical hyperalgesia.2011
- Author(s)
  Kanaoka, D., Sekiguchi, F., Nakagawa, M., Aoki, Y., Nishimoto, Y., Yoshida, S., Matsunami, M., Kawabata, A.
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] AKAP-dependent modulation of phosphorylation levels of Cav3.2 T-type calcium channels by protein kinase A and calcineurin: implications for mechanical pain sensitivity2011
- Author(s)
  Sekiguchi, F., Kanaoka, D., Nakagawa, M., Aoki, Y., Nishimoto, Y., Yoshida, S., Matsunami, M., Kawabata, A.
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] AKAP-dependent modulation of phosphorylation levels of Ca_v3.2 T-type calcium channels by protein kinase A and calcineurin : implications for mechanical pain sensitivity2011
- Author(s)
  Sekiguchi, F., Kanaoka, D., Nakagawa, M., Aoki, Y., Nishimoto, Y., Yoshida, S., Matsunami, M., Kawabata, A
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] Sensitization of T-type calcium channels by prostaglandin E_2 via the EP4 receptor/cyclic AMP/protein kinase A pathway : a possible mechanism for mechanical hyperalgesia2011
- Author(s)
  Kanaoka, D., Sekiguchi, F., Nakagawa, M., Aoki, Y., Nishimoto, Y., Yoshida, S., Matsunami, M., Kawabata, A
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] Analysis of various biological responses induced by Helicobacter pylori extract : independent of proteinase-activated receptors?2010
- Author(s)
  Sekiguchi F, et al.
- Organizer
  16th World Congress on Basic and Clinical Pharmacology
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2010-07-20
- Data Source
  KAKENHI-PROJECT-20590097
[Presentation] サイクリックAMPにより誘起される痛覚過敏へのT型カルシウムチャネルの関与2010
- Author(s)
  青木優佳、中川舞子、関口富美子、川畑篤史
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20602016
[Presentation] 内因性硫化水素の標的分子Ca_v3.2T型カルシウムチャネルは神経因性疼痛の保持において重要な役割を示す2009
- Author(s)
  高橋知子、三谷健治、竹村元秀、関口富美子、川畑篤史
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20602016
[Presentation] Helicobacter pylori 抽出液により誘起される種々の細胞反応: Proteinase-activated receptor関与の有無について2009
- Author(s)
  関口富美子,前田優磨,松本裕喜,松波真帆,西川裕之,川畑篤史
- Organizer
  第116回日本薬理学会近畿部会
- Place of Presentation
  滋賀(口頭発表)
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-20590097
[Presentation] Effect of Helicobacter pylori extracts on prostaglandin E_2 production in human lung alveolar epithelial A549 cells. XXXVI2009
- Author(s)
  Maeda Y, Sekiguchi R. Matsumoto Y. Nishikawa H. Kawabata A.
- Organizer
  International Congress of Physiological Sciences
- Place of Presentation
  Kyoto(ポスター発表)
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PROJECT-20590097
[Presentation] Relationship between expression of PARS and infection with H. pylori in the stomach of gastric cancer patients.2009
- Author(s)
  FkmiKmi K., Sekiguchi, F., Takaoka, K Miyake K Yamamoto T., Tanaka S., Ohno K., Ishikura H., Naruse M., Kawabata A.
- Organizer
  Experimental Biology 2009
- Place of Presentation
  New Orleans(ポスター発表)
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-20590097
[Presentation] Relationship between expression of PARs and infection with H.pylori in the stomach of gastric cancer patients2009
- Author(s)
  Fukami A, Sekiguchi F, et al.
- Organizer
  Experimental Biology 2009
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-20590097
[Presentation] Effect of Helicobacter pylori extracts on prostaglandin E_2 production in human lung alveolar epithelial A549 cells2009
- Author(s)
  Maeda Y, Sekiguchi F, et al.
- Organizer
  XXXVI International Congress of Physiological Sciences
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2009-07-27
- Data Source
  KAKENHI-PROJECT-20590097
[Presentation] Helicobacter pylori 抽出液により誘起される種々の細胞反応:Proteinase-activated receptor 関与の有無について2009
- Author(s)
  関口富美子, 他
- Organizer
  第116回日本薬理学会近畿部会
- Place of Presentation
  大津
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-20590097
[Presentation] 胃癌患者より摘出した胃組織のヘリコバクター・ピロリ由来ウレアーゼ蛋白量とPAR1あるいはPAR2発現量の相関性について2009
- Author(s)
  関口富美子,深海和樹,高岡香保理,三宅建作,山本隆嗣,田中肖吾,大野耕一,石倉宏恭,成瀬光栄,川畑篤史
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜(ポスター発表)
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20590097
[Presentation] 胃癌患者より摘出した胃組織のヘリコバクター・ピロリ由来ウレアーゼ蛋白量とPAR1あるいはPAR2発現量の相関性について2009
- Author(s)
  関口富美子
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20590097
[Presentation] 胃癌細胞における内因性硫化水素の細胞増殖促進作用について．
- Author(s)
  関本晃己、関口富美子、川畑篤史．
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学（札幌）
- Data Source
  KAKENHI-PROJECT-23590122
[Presentation] NG108-15細胞とラット後根神経節細胞におけるCav3.2 T型Ca2+チャネル機能のcyclic AMP依存性増強メカニズムの解析
- Author(s)
  金岡大樹、山中瑠美、関口富美子、吉田繁、川畑篤史
- Organizer
  第122回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府）
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] Prostaglandin E2-induced sensitization of T-type Ca2+ channels: a mechanism for mechanical hyperalgesia.
- Author(s)
  Kanaoka, D., Sekiguchi, F., Nakagawa, M., Aoki Y., Nishimoto Y., Yoshida, S., Tsubota-Matsunami, M, Kawabata, A.
- Organizer
  A Satellite Symposium of IUPHAR-GI Section, International Ulcer Week 2012
- Place of Presentation
  京王プラザホテル東京（東京都）
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] 神経障害性疼痛ラットの知覚神経におけるCav3.2 T型Ca2+チャネル発現誘導には転写因子Egr-1および脱ユビキチン化酵素USP5が関与する
- Author(s)
  冨田詩織、関口富美子、坪田真帆、川畑篤史
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26460112
[Presentation] High mobility group box 1 as a target for prevention and therapeutic treatment of chemotherapy-induced neuropathic pain.
- Author(s)
  Kawabata, A., Kawaishi, Y., Nishida, T., Yamanishi, H., Kamitani, N., Tsubota, M., Sekiguchi, F., Ishikura, H., Nishibori, M.
- Organizer
  Pharmacology 2014
- Place of Presentation
  Queen Elizabeth II Conference Centre (イギリス・ロンドン)
- Year and Date
  2014-12-16 – 2014-12-18
- Data Source
  KAKENHI-PROJECT-26460710
[Presentation] 胃癌細胞において内因性に産生される硫化水素は癌細胞増殖に関与する．
- Author(s)
  関口富美子、関本晃己、川畑篤史．
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-23590122
[Presentation] 知覚神経細胞におけるcyclic AMP誘起神経突起伸長に対するT型Ca2+チャネルおよびK+チャネルの関与
- Author(s)
  前田貴史、山縣亮介、三谷健治、田中友香里、関口富美子、川畑篤史
- Organizer
  第122回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府）
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] Prevention and reversal of chemotherapy-induced neuropathic pain by HMGB1 neutralization in rodents
- Author(s)
  Kawabata, A., Kawaishi, Y., Nishida, T., Yamanishi, H., Kamitani, N., Tsubota, M., Ishikura, H., Sekiguchi, F., Nishibori, M
- Organizer
  9th FENS Forum of European Neuroscience
- Place of Presentation
  Mico - Milano Congressi (イタリア・ミラノ)
- Year and Date
  2014-07-05 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-26460710
[Presentation] マウスにおいてprostaglandin E2により誘起されるT型Ca2+チャネルを介する機械的痛覚過敏の特徴：EP2/PKA経路における足場タンパクAKAP150の重要性とEP1/PKC経路の関与について
- Author(s)
  竹中秀、中村早織、坪田真帆、関口富美子、川畑篤史
- Organizer
  第124回日本薬理学会近畿部会
- Place of Presentation
  京都ガーデンパレス、京都
- Data Source
  KAKENHI-PROJECT-23590729
[Presentation] NG108-15細胞のcyclic AMPを介した神経分化への内因性硫化水素の役割
- Author(s)
  金岡大樹、竹田優希、関口富美子、吉田繁、川畑篤史
- Organizer
  第121回日本薬理学会近畿部会
- Place of Presentation
  あわぎんホール（徳島県）
- Data Source
  KAKENHI-PROJECT-23590729

1. KAWABATA Atsufumi (20177728)

# of Collaborated Projects: 11 results

# of Collaborated Products: 79 results
2. TSUBOTA Maho (90510123)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. YOSHIDA Shigeru (60145224)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. MATSUNAMI Maho

# of Collaborated Projects: 0 results

# of Collaborated Products: 35 results
5. 西堀正洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 王登莉

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Sekiguchi Fumiko 関口 富美子

SEKIGUCHI Fumiko 関口 富美子

Research Projects

Research Products

Co-Researchers

巨核球・血小板系由来HMGB1の各種難治性疼痛への関与

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The role of change in expression levels of coagulation factors in Schwann cells in the neuropathic painPrincipal Investigator

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Study on pain modulation by the interaction of coagulation factors with HMGB1 and its clinical relevance

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Possibility for increase in efficacy and alleviation in adverse effect of anti-cancer drugs by inhibition of endogenous hydrogen sulfide synthesisPrincipal Investigator

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Roles of HMGB1, a nuclear protein, in axonal regeneration after nerve injuryPrincipal Investigator

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Roles of T-type calcium channels and calcineurin in inflammatory or neuropathic painPrincipal Investigator

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Prevention and treatment of chemotherapy-induced neuropathic pain and visceral pain by targeting HMBG1, a nuclear protein

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Study of roles of endogenous hydrogen sulfide in stomach with mucosal injuryPrincipal Investigator

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Pain regulation by PKA and calcineurin through functional modulation of T-type calcium channels

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Study on effects of Helicobacter pylori infection on expression and function of proteinase-activated receptors in gastric mucosal epithelium.Principal Investigator

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Involvement of the gasotransmitter hydrogen sulfide in neurogenic pain

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Roles for hydrogen sulfide, a novel endogenous gasotransmitter, in nociceptive processing

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G蛋白共役型プロテアーゼ受容体による消化管運動調節メカニズムの解析Principal Investigator

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Sekiguchi Fumiko 関口富美子

SEKIGUCHI Fumiko 関口富美子