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FUJIWARA Tamaki  藤原 環

ORCIDConnect your ORCID iD *help
Researcher Number 90274092
Other IDs
Affiliation (based on the past Project Information) *help 2007 – 2008: Hiroshima University, 大学院・医歯薬学総合研究科, 助教
2005 – 2006: 広島大学, 大学院医歯薬学総合研究科, 助手
2002 – 2005: 広島大学, 大学院・医歯薬学総合研究科, 助手
1996 – 2001: 広島大学, 歯学部, 助手
Review Section/Research Field
Principal Investigator
Morphological basic dentistry / Bacteriology (including Mycology)
Except Principal Investigator
Biological Sciences / Bacteriology (including Mycology) / Bacteriology (including Mycology) / Morphological basic dentistry / Morphological basic dentistry
Keywords
Principal Investigator
溶菌酵素 / う蝕 / 基質特異性 / 口腔レンサ球菌 / レンサ球菌 / コアグラーゼ陰性 / MRSA / ブドウ球菌 / 抗MRSA / 結晶構造解析 … More / 細胞壁ペプチドグリカン / コアグラーゼ陰性ブドウ球菌 / D-Ala-Gly endopeptidase / endopeptidase resistance / lysostaphin / epr / Staphylococcus aureus … More
Except Principal Investigator
黄色ブドウ球菌 / MRSA / Staphylococcus aureus / 抗菌ペプチド / Exfoliative toxin / Cdt / ET / mecA / PFGE / antibiotic resistance / transglycosylase / 薬剤耐性 / CDT / 細胞膨化致死毒素 / apoptosis / lipoptrotein / Cytolethal distending toxin / ATL / 先天性免疫 / デスモグレイン / ETD / 細胞壁 / 溶菌酵素 / 伝染性膿痂疹 / 表皮剥脱毒素 / defensin / antimicrobial peptide / Cytolethal Distending Toxin / Periodontopathogenic / 細胞膨化壊死毒素 / 歯周病細菌 / Omp / A.actinomycetemcomitans / ディフェンシン / 歯周病原菌 / ribozyme / Microarray / sugar metabolism / リボザイム / マイクロアレイ / 糖代謝 / 微生物ゲノム / とびひ / ETB / ETA / バクテリオファージ / transposon / cell wall / moenomycin / methicillin / vancomycin / 細胞膜 / 細胞壁合成 / トランスポゾン / モエノマイシン / メチシリン / バンコマイシン / CDTABC complex / ctinibacillus actinomycetemcomitams / 細胞周期 / 歯周病 / 毒素 / cell cycle / Actinobacillus actinomycetemcomitans / Mブロック / G2 / CDTABC複合体 / A ctinibacillus actinomycetemcomitarns / STAPHYLOCOCCUS AUREUS / AUTOLYSIN / BACTERIOLYTIC ENZYME / PCG / LTA / オートリシン / 細菌感染 / 上皮細胞 / 抗菌性ペプチド / 感染症 / 歯周病原因菌 / 化学療法剤 / 発現調節機序 / 発現調節性因子 / 病原性因子 / 血清 / 表皮 / プロテアーゼ / セリンプロテアーゼ / 結晶構造解析 / S. sobrinus / S. mutans / 口腔内レンサ球菌 / S.sobrinus / S.mutans / 細胞壁ペプチドグリカン / 口腔レンサ球菌 / デスモゾーム蛋白 / EDIN-B / desmoglein / exfoliative toxin / dnaQ49 / Cdc42 / CNF / Rac / Rho / Small G protein Less
  • Research Projects

    (18 results)
  • Research Products

    (8 results)
  • Co-Researchers

    (6 People)
  •  黄色ブドウ球菌の病原性因子発現に影響を及ぼす外来性因子に関する研究

    • Principal Investigator
      小松澤 均
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kagoshima University
      Hiroshima University
  •  Study on the interaction between periodontal bacteria and human antimicrobial peptides

    • Principal Investigator
      KOMATSUZAWA Hitoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Kagoshima University
      Hiroshima University
  •  Research on autolytic enzyme produced by oral streptococciPrincipal Investigator

    • Principal Investigator
      FUJIWARA Tamaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  表皮剥脱毒素スーパーファミリーの作用機構に関する研究

    • Principal Investigator
      菅井 基行
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hiroshima University
  •  口腔レンサ球菌の産生する自己溶解酵素Amlに関する研究Principal Investigator

    • Principal Investigator
      藤原 環
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  Interaction of sugar metabolism with antibiotic susceptibility in Staphylococcus aureus

    • Principal Investigator
      KOMATSUZAWA Hitoshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Integrated Research on pathogenic factors of periodontal pathogens

    • Principal Investigator
      SUGAI Motoyuki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  表皮剥脱毒素スーパーファミリーの作用機構に関する研究

    • Principal Investigator
      菅井 基行
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hiroshima University
  •  Genomics and post-genomics of Staphylococcus aureus causing bullous impetigo

    • Principal Investigator
      SUGAI Motoyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  表皮剥脱毒素遺伝子スーパーファミリーの作用機構に関する研究

    • Principal Investigator
      菅井 基行
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hiroshima University
  •  S.mutans,S.sobrinusを選択的に溶解する溶菌酵素の研究

    • Principal Investigator
      菅井 基行
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  抗MRSA作用を持つコアグラーゼ陰性ブドウ球菌が産生する溶菌酵素に関する研究Principal Investigator

    • Principal Investigator
      藤原 環
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Hiroshima University
  •  Investigation of antibiotic resistance by total analysis of cell wall biosynthesis in methicillin-resistant

    • Principal Investigator
      KOMATSUZAWA Hitoshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  致死活性を有する新奇表皮剥脱毒素の作用機構に関する研究

    • Principal Investigator
      菅井 基行
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Hiroshima University
  •  A study on the function of cell-cycle specific inhibitor, CDT

    • Principal Investigator
      SUGAI Motoyuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  病原大腸菌が産生する毒素CNFの基質特異性についての研究

    • Principal Investigator
      SUGAI Motoyuki
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Hiroshima University
  •  黄色ブドウ球菌ペプチドグリカン架橋形式の分子機序Principal Investigator

    • Principal Investigator
      藤原 環
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Hiroshima University
  •  REGULATION MECHANISM OF STAPHYLOCOCCUS AUREUS LYTIC ENZYME

    • Principal Investigator
      SUGINAKA Hidekazu
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      HIROSHIMA UNIVERSITY

All 2009 2005 2004 2003

All Journal Article

  • [Journal Article] Automutanolysin disrupts clinical isolates of cariogenic streptococci in biofilms and ploanktonic cells.2009

    • Author(s)
      Panida Thanyasrisung, Hitoshi Komatsuzawa, Goh Yoshimura, Tamaki Fujiwara, Sakuo Yamada, Katsuyuki Kosai, Kazuhiro Eto, Yuichi Izumi, Motoyuki Sugai.
    • Journal Title

      Oral Microbiology and Immunology (in press)

    • Data Source
      KAKENHI-PROJECT-19791345
  • [Journal Article] Mutation analysis of the residues in the glycylglycine endopeptidase ALE-12005

    • Author(s)
      T.Fujiwara et al.
    • Journal Title

      Journal of Bacteriology 187-2

      Pages: 480-487

    • Data Source
      KAKENHI-PROJECT-16017268
  • [Journal Article] Mutation analysis of the histidine residues in the glycyl-glycine endopeptidase ALE-12005

    • Author(s)
      Tamaki Fujiwara et al.
    • Journal Title

      Journal of Bacteriology 187

      Pages: 480-487

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390143
  • [Journal Article] Mutation analysis of the Histidine residues in the glycylglycine endopeptidase ALE-1.2005

    • Author(s)
      Tamaki Fujiwara, Shin Aoki, Hitoshi Komatsuzawa, Tetsuya Nishida, Masaru Ohara, Hidekazu Suginaka, Motoyuki Sugai
    • Journal Title

      Journal of Bacteriology 187

      Pages: 480-487

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390143
  • [Journal Article] The gate controlling cell wall synthesis in Staphylococcus aureus.2004

    • Author(s)
      H.Komatsuzawa, T.Fujiwara, H.Nishi, S.Yamada, M.Ohara, N.McCallum, B.Berger-Baechi, M.Sugai
    • Journal Title

      Molecular Microbiology 53

      Pages: 1221-1231

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390143
  • [Journal Article] Reduced content of lysyl-phosphatidylglycerol in the cytoplasmic membrane affects susceptibility to moenomycin, together with vancomycin, gentamycin and other antimicrobial peptides in Staphylococcus aureus.2004

    • Author(s)
      Hiromi Nishi, Hitoshi Komatsuzawa, Tamaki Fujiwara, Nadine McCallum, Motoyuki Sugai
    • Journal Title

      Antimicrobial Agents and Chemotherapy 48

      Pages: 4800-4807

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390143
  • [Journal Article] Moenomycin-resistance is associated with vancomycin-intermediate susceptibility in Staphylococcus aureus.2003

    • Author(s)
      Hiromi Nishi, Hitoshi Komatsuzawa, Sakuo Yamada, Tamaki Fujiwara, Masaru Ohara, Kouji Ohta, Masaru Sugiyama, Takenori Ishikawa, Motoyuki Sugai
    • Journal Title

      Microbiology and Immunology 47

      Pages: 927-935

    • NAID

      10012547869

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390143
  • [Journal Article] Staphylococcus aureus susceptibility to innate antimicrobial peptides, beta-defensins and CAP 18 expressed by human keratinocytes.2003

    • Author(s)
      Kazushige Midorikawa, Kazuhisa Ouhara, Hitoshi Komatsuzawa, Toshihisa Kawai, Sakuo Yamada, Tamaki Fujiwara, Kenshi Yamazaki, Koji Sayama, Martin A.Taubman, Hidemi Kurihara, Koji Hashimoto, Motoyuki Sugai
    • Journal Title

      Infection and Immunity 71

      Pages: 3730-3739

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390143
  • 1.  SUGAI Motoyuki (10201568)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 5 results
  • 2.  KOMATSUZAWA Hitoshi (90253088)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 5 results
  • 3.  OHARA Masaru (80253095)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 3 results
  • 4.  KANBARA Kenji (60305141)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  OOGAI Yuichi (40511259)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  SUGINAKA Hidekazu (70028736)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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