FURUSE MIKIO 古瀬幹夫

… Alternative Names

Researcher Number	90281089
Other IDs
Affiliation (Current)	2019: 生理学研究所, 生体機能調節研究領域, 教授
Affiliation (based on the past Project Information) *help	2016 – 2019: 生理学研究所, 生体機能調節研究領域, 教授 2017: 自然科学研究機構, 生理学研究所・細胞構造研究部門, 教授 2016: 自然科学研究機構生理学研究所, 脳形態解析研究部門, 教授 2015: 生理学研究所, 大脳皮質機能研究系, 教授 2014: 神戸大学, 医学(系)研究科(研究院), 教授 … More
Review Section/Research Field	Principal Investigator Cell biology / Cell biology / General medical chemistry / Biological Sciences / Pathological medical chemistry / Basic Section 44010:Cell biology-related Except Principal Investigator Pathological medical chemistry / Biological Sciences / General medical chemistry / Kidney internal medicine / Structural biochemistry
Keywords	Principal Investigator タイトジャンクション / 上皮細胞 / クローディン / 細胞接着 / 細胞間接着 / オクルディン / ZO-1 / 上皮バリア機能 / GFP / 皮膚 … More Except Principal Investigator タイトジャンクション / クローディン / オクルディン / ノックアウト / 上皮細胞 / ZO-1 / claudin / tight junction / occludin / 細胞間接着 / ドラッグデリバリー / ZO-2 / ノックアウトマウス / PDZドメイン / ターゲッティング / カドヘリン / アドヘレンスジャンクション / 内皮細胞 / ES細胞 / 細胞接着 / 相同組換え / 極性 / intercellular junction / cell adhesion / knockout / epithelial cells / 細胞間接着装置 / 裏打ち蛋白質 / バリアー / GFP / MUPP1 / CLAUDIN / TIGHT JUNCTION / 電子顕微鏡 / 上皮間バリアー / 血液脳関門 / cell-cell adhesion / epidermal barrier / knockout mouse / Sカテニン / 蛋白分解 / Wntシグナル / APC / GSK3β / アキシン / アドへレンスジャンクション / 細胞極性 / 自己抗体 / 接着分子 / 骨 / 脳 / 胃 / ドミナントネガティブ / 阻害ペプチド / embryonic stem cell / embryoid body / paracellular pathway / drug delivery / barrier / 重合 / ストランド / FRAP / オフルディン / ZO-3 / MAGUK / KNOCK-OUT / UNDERLYSING PROTEINS / PDZ DOMAIN / CELL ADHESION / BARRIER / コネキシン / ギャンプジャンクション / キメラ分子 / 二次元結晶 / 遺伝子発現 / ギャップジャンクション / 膜蛋白質 / 結晶化 / OCCLUDIN / CONNEXIN / GAP JUNCTION / CHIMERIC MOLECULE / CRYSTALIZATION / GENE FAMILY / Paracellular pathway / ネフロン / 腸管病原性大腸菌 / ウェルシュ菌 / 上皮細胞バリアー / 3型分泌機構 / インチミン / Tir / 水分蒸散 / EPEC / Caco2 / 上皮細胞間電気抵抗 / tight iunction / 13 aracellular pathway / nephron / enteropathogenic E. coli / ERM蛋白質 / 細胞増殖 / Snail / がん / 上皮間葉転換 / 転移浸潤 / メルリン / 大腸癌 / ラディキシン / α-カテニン / β-カテニン / ERM / ERM proteins / cell proliferation / コンパートメント / 血管 / Zo-1 / blood-brain barrier / compartment / イメージング / 光学顕微鏡 / 磁気共鳴画像 / 画像解析 / トレーニング / 支援活動 / 科研費 / 機能的磁気共鳴画像 / 細胞間短絡路 / 近位尿細管 / 集合管 / 腎臓血管内皮細胞 / claudin-2 / 腎近位尿細管 / ネフロン内不均一性 / claudin-15 / 腎血管内皮細胞 / claudin-8 / 腎集合管 / 傍細胞経路 / Na/Cl輸送 / タンパク質間相互作用阻害薬 / ケミカルバイオロジー / アントラニル酸 / フラボノイド / グリチルリチン / 医薬品吸収促進剤 / バリア強化剤 / Wntシグナル伝達系 / Dishevelled阻害剤 / トリプルネガティブ乳がん / 細胞形態変化 / DVL阻害剤 / タンパク質間相互作用 / NMRスクリーニング / インシリコスクリーニング / LIMキナーゼ / 細胞骨格制御 / アクチン / 細胞骨格 / タンパク質間相互作用阻害剤 / 中分子創薬 Less

３細胞結合領域の細胞間隙バリアの分子機構と生理的意義の解明Principal InvestigatorOngoing
- Principal Investigator
  
  古瀬幹夫
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  National Institute for Physiological Sciences
先端バイオイメージング支援プラットフォームOngoing
- Principal Investigator(Support)
  
  狩野方伸
- Project Period (FY)
  2016 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
- Research Institution
  National Institute for Physiological Sciences
Reconstitution of paracellular transport by establishment of a claudin-deficient epithelial cell line.Principal Investigator
- Principal Investigator
  
  古瀬幹夫
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  National Institute for Physiological Sciences
Dynamic mechanisms of regurating cell-cell junction and cell shape of epithelial cells unravelled by protein structure information
- Principal Investigator
  
  HIROAKI Hidekazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Nagoya University
The molecular mechanism underlying the epithelial barrier formation by tricellular tight junctionsPrincipal Investigator
- Principal Investigator
  
  Furuse Mikio
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  National Institute for Physiological Sciences
  Kobe University
Roles of claudins in kidney water and electrolyte transport
- Principal Investigator
  
  MUTO SHIGEAKI
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Jichi Medical University
Identification and functional analyses of novel proteins involved in the regulation of epithelial cell-cell adhesionPrincipal Investigator
- Principal Investigator
  
  FURUSE Mikio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Kobe University
Molecular mechanisms of cell-cell adhesion in cancer cellsPrincipal Investigator
- Principal Investigator
  
  FURUSE Mikio
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
  Kyoto University
Identification and characterication of novel proteins involved in epithelial morphogenesisPrincipal Investigator
- Principal Investigator
  
  FURUSE Mikio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Claudins in the epithelium/endothelium barrier dysfucrition
- Principal Investigator
  
  TSUKITA Shoichiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY
個体におけるタイトジャンクションの機能解析Principal Investigator
- Principal Investigator
  
  古瀬幹夫
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
Regulation of the tight junction barrier by synthetic peptides: Towards the development of a new drug delivery methodPrincipal Investigator
- Principal Investigator
  
  FURUSE Mikio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY
Mechanism of the paracellular molecular transport
- Principal Investigator
  
  HORIGUCHI Yasuhiko
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Molecular mechanism for cell-cell adhesion in canceration and metastasis
- Principal Investigator
  
  TSUKITA Shoichiro
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  KYOTO UNIVERSITY
タイトジャンクションの膜タンパク質クローディンの機能解析Principal Investigator
- Principal Investigator
  
  古瀬幹夫
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
The claudin family : Its involvement in interecellular sealing and epithelial polarity
- Principal Investigator
  
  TSUKITA Shoichiro
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY
CLAUDINS AND OCCLUDIN : COMPARISON WITH CONNEXIN
- Principal Investigator
  
  TSUKITA Shoichiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY
βカテニンの分解によるシグナル伝達機構
- Principal Investigator
  
  NAGAFUCHI Akira
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
Development of a new drug delivery method by the use of occludin molecules
- Principal Investigator
  
  TSUKITA Shoichiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  KYOTO UNIVERSITY
タイトジャンクションの構成分子オクルディンの高次構造と結合タンパク質の研究Principal Investigator
- Principal Investigator
  
  古瀬幹夫
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
Structure and function of occludin in tight junctions : comparison with connexin gap junctions
- Principal Investigator
  
  TSUKITA Shoichiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY
オクルディンの機能阻害によるタイトジャンクション機能の解析Principal Investigator
- Principal Investigator
  
  古瀬幹夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
The structure and functions of occludin
- Principal Investigator
  
  TSUKITA Shoichiro
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY

[Book] Cell-Cell Junctions(Fuchs E and Nelson WJ, ed., Molecular basis of the core structure of tight junctions. A Cold Spring Harbor Perspective in Biology Collection)2010
- Author(s)
  Furuse M.
- Publisher
  Cold Spring Harbor Laboratory Press.
- Data Source
  KAKENHI-PROJECT-17014044
[Book] Introduction: Claudins, Tight Junctions, and the Paracellular Barrier. Current Topics in Membranes, Vol. 65 "Claudins".(Yu A, ed. )
- Author(s)
  Furuse M.
- Publisher
  Elsevier(in press)
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Claudin-3-deficient C57BL/6J mice display intact brain barriers2019
- Author(s)
  Castro DM、Coisne C、Lazarevic I、Baden P、Hata M、Iwamoto N、Francisco DMF、Vanlandewijck Mi、He L、Baier FA.、Stroka D、Bruggmann R、Lyck R、Enzmann G、Deutsch U、Betsholtz C、Furuse M、Tsukita Sh、Engelhardt B
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Pages: 36731-3
- DOI
  10.1038/s41598-018-36731-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02440, KAKENHI-PROJECT-16K15226
[Journal Article] A tetraspanin regulates septate junction formation in Drosophila midgut.2016
- Author(s)
  Yasushi Izumi, Minako Motoishi, Kyoko Furuse and Mikio Furuse
- Journal Title
  
  J Cell Sci
  
  Volume: 129 Pages: 1155-1164
- DOI
  10.1242/jcs.180448
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07048, KAKENHI-PROJECT-26291043
[Journal Article] Effects of Osmolality on Paracellular Transport in MDCK II Cells2016
- Author(s)
  Tokuda S, Hirai, T, Furuse, M
- Journal Title
  
  PLoS One
  
  Volume: 11
- DOI
  10.1371/journal.pone.0166904
- NAID
  120005980913
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26291043
[Journal Article] Epidermal cell turnover across tight junctions based on Kelvin’s tetrakaidecahedron cell shape2016
- Author(s)
  Yokouchi M, Atsugi T, Logtestijn MV, Tanaka RJ, Kajimura M, Suematsu M, Furuse M, Amagai M, Kubo A
- Journal Title
  
  eLife
  
  Volume: 5
- DOI
  10.7554/elife.19593
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291043, KAKENHI-PROJECT-26293259, KAKENHI-PROJECT-15K15422, KAKENHI-PROJECT-16K07066
[Journal Article] Deficiency of angulin-2/ILDR1, a tricellular tight junction-associated membrane protein, causes deafness with cochlear hair cell degeneration in mice.2015
- Author(s)
  Higashi T, Katsuno T, Furuse M, Kitajiri S
- Journal Title
  
  PLoS One
  
  Volume: 10
- DOI
  10.1371/journal.pone.0120674
- NAID
  120005745674
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293369, KAKENHI-PROJECT-26291043
[Journal Article] Effects of Hydrostatic Pressure on Carcinogenic Properties of Epithelia.2015
- Author(s)
  Tokuda S, Kim YH, Matsumoto H, Muro S, Hirai T, Mishima M, Furuse M.
- Journal Title
  
  PLoS One
  
  Volume: 10(12)
- DOI
  10.1371/journal.pone.0145522
- NAID
  120005753860
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461156, KAKENHI-PROJECT-26291043
[Journal Article] Claudin-2 Knockout by TALEN-Mediated Gene Targeting in MDCK Cells: Claudin-2 Independently Determines the Leaky Property of Tight Junctions in MDCK Cells2015
- Author(s)
  Tokuda S, Furuse M
- Journal Title
  
  PLoS One
  
  Volume: 10
- DOI
  10.1371/journal.pone.0119869
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26291043
[Journal Article] Molecular organization and function of invertebrate occluding junctions2014
- Author(s)
  Izumi Y, Furuse M.
- Journal Title
  
  Semin Cell Dev Biol
  
  Volume: 36 Pages: 186-193
- DOI
  10.1016/j.semcdb.2014.09.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26291043
[Journal Article] Molecular organization of tricellular tight junctions2014
- Author(s)
  Furuse M, Izumi Y, Oda Y, Higashi T, Iwamoto N
- Journal Title
  
  Tissue Barriers
  
  Volume: 2
- DOI
  10.4161/tisb.28960
- NAID
  130004756433
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26291043
[Journal Article] Tricellulin regulates junctional tension of epithelial cells at tricellular contacts via Cdc422014
- Author(s)
  Oda Y, Otani T, Ikenouchi J, Furuse M.
- Journal Title
  
  J Cell Sci
  
  Volume: 127 Pages: 4201-12
- DOI
  10.1242/jcs.150607
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24657131, KAKENHI-PROJECT-24770197, KAKENHI-PROJECT-25711012, KAKENHI-PUBLICLY-26112713, KAKENHI-PROJECT-26291043
[Journal Article] ZO-1 Knockout by TALEN-mediated gene targeting in MDCK Cells: involvement of ZO-1 in the regulation of cytoskeleton and cell shape2014
- Author(s)
  Tokuda S, Higashi T, Furuse, M
- Journal Title
  
  PLoS One
  
  Volume: 9
- DOI
  10.1371/journal.pone.0104994
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26291043
[Journal Article] Flightless-I (Fli-I) regulates the actin assembly activity of diaphanous-related formins (DRFs) Daam1 and mDia1 in cooperation with active Rho GTPase.2010
- Author(s)
  Higashi T, Ikeda T, Murakami T, Shirakawa R, Kawato M, Okawa K, Furuse M, Kimura T, Kita T, Horiuchi H.
- Journal Title
  
  J Biol Chem 285
  
  Pages: 16231-16238
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Molecular basis of the core structure of tight junctions2010
- Author(s)
  Furuse M
- Journal Title
  
  Cold Spring Harb Perspect Biol 2(online)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Claudin-2-deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules.2010
- Author(s)
  Muto S, Hata M, Taniguchi J, Tsuruoka S, Moriwaki K, Saitou M, Furuse K, Sasaki H, Fujimura A, Imai M, Kusano E, Tsukita S, Furuse M.
- Journal Title
  
  Proc Natl Acad Sci U S A 107
  
  Pages: 8011-8016
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells2009
- Author(s)
  Takahashi S, Iwamoto N, Sasaki H, Ohashi M, Oda Y, Tsukita S, Furuse M.
- Journal Title
  
  J Cell Sci 122
  
  Pages: 985-994
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Generation of transgenic medaka expressing claudin7-EGFP for imaging of tight junctions in living medaka embryos2009
- Author(s)
  Miyamoto T, Momoi A, Kato K, Kondoh H, Tsukita S. Furuse M, Furutani-Seiki M
- Journal Title
  
  Cell Tissue Res 335
  
  Pages: 465-471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Similar and distinct properties of MUPP1 and PaTJ, two homologous PDZ domain-containing tight-junction proteins.2009
- Author(s)
  Adachi M, Hamazaki Y, Kobayashi Y, Itoh M, Tsukita S, Furuse M, Tsukita S.
- Journal Title
  
  Mol Cell Biol 29
  
  Pages: 2372-2389
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] The role of claudin-based tight junctions in morphogenesis.2009
- Author(s)
  Furuse M, Moriwaki K.
- Journal Title
  
  Ann N Y Acad Sci 1165
  
  Pages: 58-61
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Generation of transgenic medaka expressing claudin7-EGFP for imaging of tight junctions in living medaka embryos.2009
- Author(s)
  Miyamoto T, Momoi A, Kato K, Kondoh H, Tsukita S, Furuse M, Furutani-Seiki M.
- Journal Title
  
  Cell Tissue Res 335
  
  Pages: 465-471
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] The role of claudin-based tight junctions in morphogenesis2009
- Author(s)
  Furuse M
- Journal Title
  
  Ann N Y Acad Sci 1165(昨年度報告書で印刷中と記載したもの)
  
  Pages: 58-61
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Knockout animals and natural mutations as experimental and diagnostic tool for studying tight junction functions in vivo2009
- Author(s)
  Furuse M
- Journal Title
  
  Biochim Biophys Acta 1788(昨年度報告書で印刷中と記載したもの)
  
  Pages: 813-819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Knockout animals and natural mutations as experimental and diagnostic tool for studying tight junction functions in vivo.2009
- Author(s)
  Furuse M.
- Journal Title
  
  Biochim Biophys Acta 1788
  
  Pages: 813-819
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Loss of occludin affects tricellular localization of tricellulin2008
- Author(s)
  Ikenouchi J, Sasaki H, Tsukita S, Furuse M, Tsukita S
- Journal Title
  
  Mol Biol Cell 19
  
  Pages: 4687-4693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Megaintestine in claudin-15-deficient mice2008
- Author(s)
  Tamura, A., Kitano, Y., Hata, M., Katsuno, T., Moriwaki, K., Sasaki, H., Hayashi, H., Suzuki, Y, Noda, T., Furuse, M., Tsukita, S., Tsukita, S.
- Journal Title
  
  Gastroenterology 134
  
  Pages: 523-534
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370078
[Journal Article] Loss of occludin affects tricellular localization of tricellulin.2008
- Author(s)
  Ikenouchi J, Sasaki H, Tsukita S, Furuse M, Tsukita S.
- Journal Title
  
  Mol Biol Cell 19
  
  Pages: 4687-4693
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Identification of adherens junction-associated GTPase activating proteins by the fluorescence localization-based expression cloning.2008
- Author(s)
  Matsuda M, Kobayashi Y, Masuda S, Adachi M, Watanabe T, Yamashita JK, Nishi E, Tsukita S, Furuse M.
- Journal Title
  
  Exp Cell Res 314
  
  Pages: 939-949
- NAID
  120001384679
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Identification of adherens junction-associated GTPase activating proteinsby the fluorescence localization-based expression cloning2008
- Author(s)
  Matsuda, M., Kobayashi, Y., Masuda, S., Adachi, M., Watanabe, T., Yamashita, JK., Nishi, E., Tsukita, S., Furuse, M.
- Journal Title
  
  Exp. Cell Res. 314
  
  Pages: 939-949
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370078
[Journal Article] Megaintestine in claudin-15-deficient mice2008
- Author(s)
  Tamura A, Kitano Y, Hata M, Katsuno T, Moriwaki K, Sasaki H, Hayashi H, Suzuki Y, Noda T, Furuse M, Tsukita S, Tsukita S.
- Journal Title
  
  Gastroenterology 134
  
  Pages: 523-534
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Molecular characterization of angiomotin/JEAP family proteins : interaction with MUPP1/Patj and their endogenous properties.2007
- Author(s)
  Sugihara-Mizuno, Y., Adachi, M., Kobayashi, Y, Hamazaki, Y, Nishimura, M., Imai, T., Furuse, M., Tsukita, S.
- Journal Title
  
  Genes Cells 12
  
  Pages: 473-486
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370078
[Journal Article] Tight junctions containing claudin 4 and 6 are essential for blastocyst formation in preimplantation mouse embryos.2007
- Author(s)
  Moriwaki K, Tsukita S, Furuse M.
- Journal Title
  
  Dev Biol 312
  
  Pages: 509-522
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization2007
- Author(s)
  Ikenouchi, J., Umeda, K., Tsukita, S., Furuse, M., Tsukita, S.
- Journal Title
  
  J. Cell Biol. 176
  
  Pages: 779-786
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370078
[Journal Article] Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization.2007
- Author(s)
  Ikenouchi J, Umeda K, Tsukita S, Furuse M, Tsukita S.
- Journal Title
  
  J Cell Biol 176
  
  Pages: 779-786
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/PaTJ and their endogenous properties.2007
- Author(s)
  Sugihara-Mizuno Y, Adachi M, Kobayashi Y, Hamazaki Y, Nishimura M, Imai T, Furuse M, Tsukita S.
- Journal Title
  
  Genes Cells 12
  
  Pages: 473-486
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Tight junctions containing claudin 4 and 5 are essential for blastocyst formation in preimplantation mouse embryos2007
- Author(s)
  Moriwaki, K., Tsukita, S., Furuse, M.
- Journal Title
  
  Dev. Biol. 312
  
  Pages: 509-522
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370078
[Journal Article] Claudins in occluding junctions of humans and flies2006
- Author(s)
  Furuse, M.
- Journal Title
  
  Trend Cell Biol. 181
  
  Pages: 181-188
- Data Source
  KAKENHI-PROJECT-18370078
[Journal Article] Claudins in occluding junctions of humans and flies.2006
- Author(s)
  Furuse, M., Tsukita, S.
- Journal Title
  
  Trend Cell Biol. 16
  
  Pages: 181-188
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370078
[Journal Article] Claudins in occluding junctions of humans and flies.2006
- Author(s)
  Furuse, M.
- Journal Title
  
  Trends Cell Biol. 16
  
  Pages: 181-188
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Claudins in occluding junctions of humans and flies.2006
- Author(s)
  Furuse M, Tsukita S.
- Journal Title
  
  Trends Cell Biol 16
  
  Pages: 181-188
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Claudins in occluding junctions of humans and flies2006
- Author(s)
  Furuse, M., Tuskita, S.
- Journal Title
  
  Trend Cell Biol. 16
  
  Pages: 181-188
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370078
[Journal Article] ZO-1 and ZO-2 independently determine where claudins are polymerized in tight junction strand formation.2006
- Author(s)
  Umeda, K., Ikenouchi, J., Katahira-Tayama, S., Furuse, K., Sasaki, H., Nakayama, M., Matsui, T., Tsukita, S., Furuse, M., Tsukita, S.
- Journal Title
  
  Cell 126
  
  Pages: 741-754
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370078
[Journal Article] ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation.2006
- Author(s)
  Umeda K, Ikenouchi J, Katahira-Tayama S, Furuse K, Sasaki H, Nakayama M, Matsui T, Tsukita S, Furuse M, Tsukita S.
- Journal Title
  
  Cell 126
  
  Pages: 741-754
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Normal establishment of epithelial tight junctions in mice and cultured cells lacking expression of ZO-3, a tight-junction MAGUK protein.2006
- Author(s)
  Adachi M, Inoko A, Hata M, Furuse K, Umeda K, Itoh M, Tsukita S.
- Journal Title
  
  Mol Cell Biol 26
  
  Pages: 9003-9015
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells.2005
- Author(s)
  Ikenouchi J, Furuse M, Furuse K, Sasaki H, Tsukita S, Tsukita S.
- Journal Title
  
  J Cell Biol 171
  
  Pages: 939-945
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice.2005
- Author(s)
  Miyamoto T, Morita K, Takemoto D, Takeuchi K, Kitano Y, Miyakawa T, Nakayama K, Okamura Y, Sasaki H, Miyachi Y, Furuse M, Tsukita S.
- Journal Title
  
  J Cell Biol 169
  
  Pages: 527-538
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Expression patterns of claudin family of tight junction membrane proteins in developipa mouse submandibular gland2004
- Author(s)
  Hashizume A., Ueno T., Furuse M., Tsukita S., Nakanishi Y., Hieda Y.
- Journal Title
  
  Dev.Dyn. 231
  
  Pages: 425-431
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] JACOP, a novel plaque protein localizing at the apical junctional complex with sequence similarity to cinaulin2004
- Author(s)
  Ohnishi H., Nakahara T., Furuse K., Sasaki H., Tsukita S., Furuse M
- Journal Title
  
  J.Biol.Chem 279
  
  Pages: 46014-46022
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] JACOP, a novel plaque protein localizing at the apical junctional complex with sequence similarity to cingulin2004
- Author(s)
  Ohnishi H, Nakahara T, Furuse K, Sasaki H, Tsukita Sh, Furuse M
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 46014-46022
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] Expression patterns of claudins, tight junction adhesion molecules, in the inner ear.2004
- Author(s)
  Kitajiri, S., Furuse, M., Morita, K., Saishin-Kiuchi, Y., Kido, H., Ito, J., Tsukita, Sh.
- Journal Title
  
  Hear.Res. 187
  
  Pages: 25-34
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] JACOP, a novel plaque protein localizing at the apical junctional complex with sequence similarity to cingulin.2004
- Author(s)
  Ohnishi, H., Nakahara, T., Furuse, K., Sasaki, H., Tsukita, S., Furuse, M.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 46014-46022
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] Establishment and characterization of cultured epithelial cells lacking expression of ZO-12004
- Author(s)
  Umeda K., Matsui T., Nakayama M., Furuse K., Sasaki H., Furuse M., Tsukita S.
- Journal Title
  
  J.Biol.Chem. 43
  
  Pages: 44785-44794
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] A peculiar internalization of claudins, tight junction-apecific adhesion molecules, during the intercellular movement of epithelial cells2004
- Author(s)
  Matsuda M., Kubo A., Furuse M., Tsukita S.
- Journal Title
  
  J.Cell Sci. 117
  
  Pages: 1247-1257
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] Establishment and characterization of cultured epithelial cells lacking expression of ZO-1.2004
- Author(s)
  Umeda, K., Matsui, T., Nakayama, M., Furuse, K., Sasaki, H., Furuse, M., Tsukita, Sh.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 44785-44794
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] Expression patterns of claudins, tight junction adhesion molecules, in the inner ear2004
- Author(s)
  Kitajiri S, Furuse M, Morita K, Saishin-Kiuchi Y, Kido H, Ito J, Tsukita Sh
- Journal Title
  
  Hear.Res 187
  
  Pages: 25-34
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] Establishment and characterization of cultured epithelial cells lacking expression of ZO-12004
- Author(s)
  Umeda K, Matsui T, Nakayama M, Furuse K, Sasaki H, Furuse M, Tsukita Sh
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 44785-44794
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] Expression and distribution of ZO-3, a tight junction MAGUK protein, in mouse tissues.2003
- Author(s)
  Inoko A, Itoh M, Tamura A, Matsuda M, Furuse M, Tsukita Sh
- Journal Title
  
  Genes Cells 8
  
  Pages: 837-845
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] Dynamic behavior of paired claudin strands within apposing plasma membranes2003
- Author(s)
  Sasaki H, Matsui C, Furuse K, Mimori-Kiyosue Y, Furuse M, Tsukita Sh
- Journal Title
  
  PNAS 100
  
  Pages: 3971-3976
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice.2003
- Author(s)
  Nitta, T., Hata, M., Gotoh, S., Seo, Y., Sasaki, H., Hashimoto, N., Furuse, M., Tsukita, Sh.
- Journal Title
  
  J.Cell Biol. 161
  
  Pages: 653-660
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice.2003
- Author(s)
  Nitta T, Hata M, Gotoh S, Seo Y, Sasaki H, Hashimoto N, Furuse M, Tsukita Sh
- Journal Title
  
  J.Cell Biol. 161
  
  Pages: 653-660
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] Expression and distribution of ZO-3, a tight junction MAGUK protein, in mouse tissues.2003
- Author(s)
  Inoko, A., Itoh, M., Tamura, A., Matsuda, M., Furuse, M., Tsukita, Sh.
- Journal Title
  
  Genes Cells 8
  
  Pages: 837-845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] Dynamic behavior of paired claudin strands within apposing plasma membranes.2003
- Author(s)
  Sasaki, H., Matsui, C., Furuse, K., Mimori-Kiyosue, Y., Furuse, M., Tsukita, Sh.
- Journal Title
  
  PNAS 100
  
  Pages: 3971-3976
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390090
[Journal Article] Claudin-based tight junctions are crucial for the mammalian epidermal barrier : a lesson from claudin-1-deficient mice.2002
- Author(s)
  Furuse M., et al.
- Journal Title
  
  J.Cell Biol. 156
  
  Pages: 1099-1111
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12144208
[Journal Article] Claudin-based tight junctions are crucial for the mammalian epidermal barrier : A lesson from claudin-1-deficient mice.2002
- Author(s)
  Furuse, M. et al.
- Journal Title
  
  J. Cell Biol. 156
  
  Pages: 1099-1111
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219210
[Journal Article] Claudin-based tight junctions are crucial for the mammalian epidermal barrier : A lesson from claudin-1-deficient mice2002
- Author(s)
  Furuse, M.et al.
- Journal Title
  
  Journal of Cell Biology 156
  
  Pages: 1099-1111
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207008
[Journal Article] Claudin-based tight junctions are crucial for the mammalian epidermal barrier : A lesson from claudin-1-deficient mice.2002
- Author(s)
  Furuse, M. et al.
- Journal Title
  
  J.Cell Biol. 156
  
  Pages: 1099-1111
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219210
[Journal Article] Claudin-based tight junctions are crucial for the mammalian epidermal barrier : a lesson from claudin-1-deficient mice.2002
- Author(s)
  Furuse M, et al.
- Journal Title
  
  J. Cell Biol. 156
  
  Pages: 1099-1111
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12144208
[Journal Article] Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells.2001
- Author(s)
  Furuse M, et al.
- Journal Title
  
  J.Cell Biol. 153
  
  Pages: 263-272
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12144208
[Journal Article] Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells.2001
- Author(s)
  Furuse M., et al.
- Journal Title
  
  J.Cell Biol. 153
  
  Pages: 263-272
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12144208
[Journal Article] The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells
- Author(s)
  Takahashi S, Iwamoto N, Sasaki H, Ohashi M, Oda Y, Tsukita S, Furuse M
- Journal Title
  
  J Cell Sci (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] The Drosophila Claudin Kune-kune is Required for Septate Junction Organization and Tracheal Tube Size Control.
- Author(s)
  Nelson KS, Furuse M, Beitel GJ.
- Journal Title
  
  Genetics. (in press)
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] The role of claudin-based tight junctions in morphogenesis
- Author(s)
  Furuse. M
- Journal Title
  
  Ann N Y Acad Sci (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Claudins, tight junctions and the paracellular barrier
- Author(s)
  Furuse M.
- Journal Title
  
  Current Topics in Membranes (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Similar and Distinct Properties of MUPP1 and Patj, Two Homologous PDZ Domain-Containing Tight Junction Proteins
- Author(s)
  Adachi M, Hamazaki Y, Kobayashi Y, Itoh M, Tsukita S, Furuse M, Tsukita S
- Journal Title
  
  Mol Cell Biol (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014044
[Journal Article] Knockout animals and natural mutations as experimental and diagnostic tool for studying tight junction functions in vivo
- Author(s)
  Furuse M
- Journal Title
  
  Biochim Biophys Acta (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Establishment of a tight junction-deficient epithelial cell line by genome editing of claudin genes2019
- Author(s)
  Mikio Furuse, Tetsuaki Otani, Taichi Sugawara, Shinsaku Tokuda, Mika Watanabe, Kyoko Furuse, Osamu Nagata
- Organizer
  9th Federation of the Asian and Oceanian Physiological Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02440
[Presentation] Establishment of a tight junction-deficient epithelial cell line by genome editing of claudin genes2019
- Author(s)
  Mikio Furuse, Tetsuaki Otani, Taichi Sugawara, Shinsaku Tokuda, Mika Watanabe, Kyoko Furuse, Osamu Nagata
- Organizer
  9th Federation of the Asian and Oceanian Physiological Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15226
[Presentation] ZO family proteins regulate epithelial polarity independent of tight junction strand assembly2019
- Author(s)
  Tetsuhisa Otani, Shinsaku Tokuda, Mikio Furuse
- Organizer
  9th Federation of the Asian and Oceanian Physiological Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15226
[Presentation] ZO family proteins regulate epithelial polarity independent of tight junction strand assembly2019
- Author(s)
  Tetsuhisa Otani, Shinsaku Tokuda, Mikio Furuse
- Organizer
  9th Federation of the Asian and Oceanian Physiological Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02440
[Presentation] The role of tight junction-associated plaque proteins ZO-1 and ZO-2 in epithelial polarity2018
- Author(s)
  古瀬幹夫、大谷哲久
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K15226
[Presentation] Angulin-1 regulates vertical elongation of tricellular tight junction by interacting with scaffolding proteins2018
- Author(s)
  Taichi Sugawara, Mikio Furuse
- Organizer
  第70回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-16K15226
[Presentation] ZO family proteins regulate epithelial polarity independent of Tight Junction strand assembly2018
- Author(s)
  Tetsuhisa Otani, Shinsaku Tokuda, Mikio Furuse
- Organizer
  第70回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-16K15226
[Presentation] Angulin-1 regulates vertical elongation of tricellular tight junction by interacting with scaffolding proteins2018
- Author(s)
  Taichi Sugawara, Mikio Furuse
- Organizer
  第70回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-18H02440
[Presentation] ZO family proteins regulate epithelial polarity independent of Tight Junction strand assembly2018
- Author(s)
  Tetsuhisa Otani, Shinsaku Tokuda, Mikio Furuse
- Organizer
  第70回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-18H02440
[Presentation] Tricellular tight junction and its associated proteins2016
- Author(s)
  Furuse M
- Organizer
  TJ Conference in Berlin 2016
- Place of Presentation
  Berlin, Germany
- Year and Date
  2016-09-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291043
[Presentation] Hydrostatic pressure gradient induces stratification of simple epithelial cells2016
- Author(s)
  Tokuda S, Furuse M
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ、京都府京都市
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26291043
[Presentation] Revisiting the roles of Tight Junctions in epithelial polarity2016
- Author(s)
  Otani T, Tokuda S, Watanabe M, Furuse M
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ、京都府京都市
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-26291043
[Presentation] Molecular organization of tricellular tight junctions2015
- Author(s)
  Furuse M
- Organizer
  The American Physiological Society at Experimental Biology 2015
- Place of Presentation
  Boston, USA
- Year and Date
  2015-04-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291043
[Presentation] Molecular dissection of septate junctions in the insect midgut and malpighian tubules2015
- Author(s)
  Furuse M, Izumi Y
- Organizer
  Society for Experimental Biology Annual Main Meeting
- Place of Presentation
  Prague, Czech Republic
- Year and Date
  2015-06-30
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291043
[Presentation] The angulin-tricellulin system at epithelial and endothelial tricellular tight junctions2015
- Author(s)
  Mikio Furuse
- Organizer
  The 18th International Symposium on Signal Transduction at the Blood-Brain and Blood-Retina Barriers
- Place of Presentation
  Paris, France
- Year and Date
  2015-07-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291043
[Presentation] PDZ-RhoGEFは細胞間接着部位に局在しアピカル面張力を制御する2010
- Author(s)
  東智仁、明石昌也、古瀬幹夫
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] 新規血管内皮Cell-cell junction関連分子はCdc42を介してアクチンフィラメントを調節する2010
- Author(s)
  明石昌也、古瀬幹夫
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Claudin downregulation by an E3 ligase2009
- Author(s)
  Furuse M
- Organizer
  Gordon research conference "Cell Contact & Adhesion"
- Place of Presentation
  Waterville Valley Resort, Waterville Valley, NH, USA
- Year and Date
  2009-06-30
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Scribbleのリン酸化修飾は、そのアドヘレンスジャンクションへの局在およびe-カドヘリンーカテニン複合体との結合を制御する2009
- Author(s)
  吉原賢、池ノ内順一、月田承一郎、古瀬幹夫.
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Tricellulin regulates actin-myosin organization at tricellular contacts2009
- Author(s)
  小田裕香子、池ノ内順一、古瀬幹夫
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] 血管内皮細胞におけるタイトジャンクションの分子構築2009
- Author(s)
  古瀬幹夫
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] 3細胞結合領域に局在する新規膜内在性タンパク質の同定と解析2009
- Author(s)
  増田小百合、佐々木博之、池ノ内順一、西英一郎、古瀬幹夫
- Organizer
  第61回日本細胞生物学会大会・第81回日本生化学会大会合同大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Identification of a novel molecular component localizing at tricellular tight junctions.2009
- Author(s)
  Furuse M.
- Organizer
  Gordon research conference "Cell Contact & Adhesion"
- Place of Presentation
  Watervalley Village, USA
- Year and Date
  2009-06-30
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Molecular basis for the barrier function of tight junctions2009
- Author(s)
  Furuse M
- Organizer
  The 7th Japan-Korea Joint Symposium on Vascular Biology
- Place of Presentation
  Ewha Woman's University, Seoul, Korea
- Year and Date
  2009-08-20
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Manner of claudin assembly within tight junction strands2009
- Author(s)
  Furuse M
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  京都国際会議場(京都府)
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Molecular basis for the barrier function of tight junctions.2009
- Author(s)
  Furuse M.
- Organizer
  The 7th Japan-Korea Joint Symposium on Vascular Biology
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Formation of tricellular tight junctions: How the extracellular space is plugged where three epithelial cells meet.2009
- Author(s)
  Furuse M.
- Organizer
  ASCB/JSCB/RIKEN CDB Meeting
- Place of Presentation
  京都
- Year and Date
  2009-09-22
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] タイトジャンクション:細胞間をシールする分子機構2009
- Author(s)
  古瀬幹夫
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] ArfGEF11は上皮細胞の細胞間接着部位に局在しアクチン細胞骨格の構成を制御する2009
- Author(s)
  東智仁、明石昌也、古瀬幹夫
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] 血管内皮のcell-cell junction新規構成分子の同定と機能解析2009
- Author(s)
  明石昌也、古瀬幹夫
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Formation of tricellular tight junctions : How the extracellular space is plugged where three epithelial cells meet2009
- Author(s)
  Furuse M
- Organizer
  2009 ASCB/JSCB/RIKEN CDB Meeting
- Place of Presentation
  京都国際会議場(京都府)
- Year and Date
  2009-09-22
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] E3ユビキチンリガーゼLNX1によるクローディンのタイトジャンクションからの消失2008
- Author(s)
  高橋千絵、岩本典子、佐々木博之、月田承一郎、古瀬幹夫
- Organizer
  第60回日本細胞生物学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] The E3 ubiquitin ligase LNX-1 downregulates claudins from tight junctions.2008
- Author(s)
  Takahashi S, Iwamoto N, Sasaki H, Tsukita S, Furuse M.
- Organizer
  48th The American Society for Cell Biology Annual Meeting.
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] The role of tight junctions in epithelial barrier function2008
- Author(s)
  Furuse M
- Organizer
  Post IID 2008 Satellite international Meeting on Auto immune Diseases
- Place of Presentation
  大津
- Year and Date
  2008-05-18
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] The E3 ubiquitin ligase LNX-1 downregulates claudins from tight junctions2008
- Author(s)
  岩本典子、高橋千絵、佐々木博之、月田承一郎、古瀬幹夫
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] The role of tight junctions in epithelial barrier function.2008
- Author(s)
  Furuse M.
- Organizer
  Post IID 2008 Satellite international Meeting on Autoimmune Diseases
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Internalization of claudins from tight junctions.2008
- Author(s)
  Furuse M.
- Organizer
  International conference Berlin 2008 "Molenular structure and Function of the tight junction"
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] The E3 ubiquitin ligase LNX-1 downregulates claudins from tight junctions2008
- Author(s)
  Iwamoto N, Takahashi S, Sasaki H, Tsukita S, Furuse M
- Organizer
  Gordon Research Conference : SIGNALING BY ADHESION RECEPTORS
- Place of Presentation
  South Hadley, Massachusetts, USA
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Internalization of claudins from tight junctions2008
- Author(s)
  Furuse M
- Organizer
  International conference Berlin 2008 "Molenular structure and Function of the tight junction"
- Place of Presentation
  Berlin, Germany
- Year and Date
  2008-04-25
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] The E3 ubiquitin ligase LNX-1 downregulates claudins from tight junctions2008
- Author(s)
  Takahashi S, Iwamoto N, Sasaki H, Tsukita S, Furuse M
- Organizer
  48th The American Society for Cell Biology Annual Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Internalization and degradation of claudins during the remodeling of tight junctions2008
- Author(s)
  Furuse M, Takahashi S, Iwamoto N
- Organizer
  CSHL Meeting on Blood/Brain Barrier Physiology : Neural Boundary and the Molecular Mechanisms of CNS Protection
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] The E3 ubiquitin ligase LNX-1 downregulates claudins from tight junctions.2008
- Author(s)
  Iwamoto N, Takahashi S, Sasaki H, Tsukita S, Furuse M.
- Organizer
  Gordon Research Conference: SIGNALING BY ADHESION RECEPTORS.
- Place of Presentation
  South Hadley, USA
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] アドヘンスジャンクションに局在する新規アクチン結合タンパク質abLIM3の同定と機能解析2008
- Author(s)
  松田美穂、山下潤、月田承一郎、古瀬幹夫
- Organizer
  第60回日本細胞生物学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] タイトジャンクションの分子構築と機能発現のメカニズム. 第32回角膜カンファレンス2008
- Author(s)
  古瀬幹夫
- Organizer
  第24回日本角膜移植学会
- Place of Presentation
  千葉
- Year and Date
  2008-03-01
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Internalization and degradation of claudins during the remodeling of tight junctions.2008
- Author(s)
  Furuse M.
- Organizer
  Cold Spring Harbor Laboraboty Meeting on Blood/Brain Barrier Physiology: Neural Boundary and the Molecular Mechanisms of CNS Protection
- Place of Presentation
  Cold Spring Harbor, USA
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] タイトジャンクション:細胞間隙をシールする分子機構2008
- Author(s)
  古瀬幹夫
- Organizer
  第56回ウイルス学会学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] クローディン15ノックアウトマウスにおける小腸肥大化の解析2007
- Author(s)
  田村淳、北野由佳、秦正樹、勝野達也、森脇一将、佐々木博之、野田哲生、古瀬幹夫、月田承一郎、月田早智子
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Epithelial and endothelial tight junctions2007
- Author(s)
  Furuse. M.
- Organizer
  4^<th> world Conference on Drug Absorption, Transport and Delivery.
- Place of Presentation
  Kanazawa, Japan
- Year and Date
  2007-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370078
[Presentation] Identification of novel protein components of the junctional complex by the fluorescence localzation-based expression cloning (EL-REX) method2007
- Author(s)
  Furuse, M.
- Organizer
  10th International Symposium on "Signal transduction in the blood-brain barrier"
- Place of Presentation
  Potsdam. Germany
- Year and Date
  2007-09-16
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Fluorescence localization-based expression cloning (FL-REX)法によるアドヘレンスジャンクション局在GTPase activating proteinの同定2007
- Author(s)
  小林由佳、松田美穂、増田小百合、足立誠、月田承一郎、古瀬幹夫
- Organizer
  第40回日本発生生物学会・第59回日本細胞生物学会合同大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] タイトジャンクションに局在する2つの類似したPDZドメイン含有分子MUPP1とPatjの解析.2007
- Author(s)
  足立誠、浜崎洋子、小林由佳、月田早智子、古瀬幹夫、月田承一郎
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Epithelial and endothelial tight junctions2007
- Author(s)
  Furuse, M.
- Organizer
  4th World Conference on Drung Absorotion, Transport and Delivery
- Place of Presentation
  Kanazawa, Japan
- Year and Date
  2007-07-21
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Idenification of novel components Iocalizing at epithelial cell-cell junction.2007
- Author(s)
  Furuse M.
- Organizer
  10th Symposium on "Signal Trandnction in the Blood-Brain Barriers"
- Place of Presentation
  Potsdam, Germany
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Epithelial and endothelial tight junctions.2007
- Author(s)
  Furuse M.
- Organizer
  4th World Conference on Drug Absorption, Transport and Delivery.
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Identification of novel protein components of the junctional complex by the fluorescence localization-based expression cloning (FL-REX) method2007
- Author(s)
  Furuse, M.
- Organizer
  10^<th> International Symposium on "Signal transduction in the blood-brain barrier"
- Place of Presentation
  Potsdam, Germany
- Year and Date
  2007-09-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18370078
[Presentation] 細胞間接着における細胞膜-細胞骨格インターフェイスとしてのZO-12007
- Author(s)
  勝野達也、梅田一彰、山崎裕自、三宅由華、和田真実、松井毅、田村淳、池ノ内順一、古瀬幹夫、月田承一郎、月田早智子
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] タイトジャンクションと皮膚のバリア機能2007
- Author(s)
  古瀬幹夫
- Organizer
  第32回日本香粧品学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] タイトジャンクションとバリア障害2007
- Author(s)
  古瀬幹夫
- Organizer
  第71回日本皮膚科学会東部支部学術大会
- Place of Presentation
  札幌
- Year and Date
  2007-09-23
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Epithelial and endothelial tight junctions2007
- Author(s)
  Furuse, M.
- Organizer
  4^<th> World Conference on Drug Absorption, Transport and Delivery
- Place of Presentation
  Kanazawa, Japan
- Year and Date
  2007-06-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18370078
[Presentation] Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells.2006
- Author(s)
  Ikenouchi J, Furuse M, Furuse K, Sasaki H, Tsukita Sa, Tsukita Sh.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology.
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Overlapping and distinct functions of two jomologous, PDZ domain-containing tight junction proteins, MUPP-1 and Patj.2006
- Author(s)
  Adachi, M, Hamazaki Y, Kobayashi Y, Itoh M, Sasaki H, Takai Y, Furuse M, Tsukita S.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology.
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Molecular dissection of tight junctions.2006
- Author(s)
  Furuse M, Ikenouchi J, Tsukita S.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology.
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] Tight junction is required for blastocyst formation in mouse early development.2006
- Author(s)
  Moriwaki K, Tsukita S, Furuse M.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology.
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17014044
[Presentation] 多角形の上皮細胞の角が接する領域の細胞間隙をいかにして閉じるか：トリセルラータイトジャンクションの分子構築
- Author(s)
  古瀬幹夫
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-26291043

1. TSUKITA Shoichiro (50155347)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. TSUKITA Sachiko (00188517)

# of Collaborated Projects: 6 results

# of Collaborated Products: 35 results
3. ITOH Masahiko (70270486)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. NAGAFUCHI Akira (80218023)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. KUBO Akiharu (70335256)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
6. YONEMURA Shigenobu (60192811)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. ADACHI Makoto (30335244)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
8. SASAKI Hiroyuki (60170693)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
9. TAMURA Atsushi (00362525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. ODA Yukako (70452498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. HORIGUCHI Yasuhiko (00183939)

# of Collaborated Projects: 1 results

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12. MIYAKE Masami (10251175)

# of Collaborated Projects: 1 results

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13. MUTO SHIGEAKI (40190855)

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14. HIROAKI Hidekazu (10336589)

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67. 岡田峰陽

# of Collaborated Projects: 0 results

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FURUSE MIKIO 古瀬 幹夫

Furuse Mikio 古瀬 幹夫

FURUSE Mikio 古瀬 幹夫

Research Projects

Research Products

Co-Researchers

３細胞結合領域の細胞間隙バリアの分子機構と生理的意義の解明Principal InvestigatorOngoing

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先端バイオイメージング支援プラットフォームOngoing

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Reconstitution of paracellular transport by establishment of a claudin-deficient epithelial cell line.Principal Investigator

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The molecular mechanism underlying the epithelial barrier formation by tricellular tight junctionsPrincipal Investigator

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Identification and functional analyses of novel proteins involved in the regulation of epithelial cell-cell adhesionPrincipal Investigator

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Molecular mechanisms of cell-cell adhesion in cancer cellsPrincipal Investigator

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Identification and characterication of novel proteins involved in epithelial morphogenesisPrincipal Investigator

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個体におけるタイトジャンクションの機能解析Principal Investigator

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Regulation of the tight junction barrier by synthetic peptides: Towards the development of a new drug delivery methodPrincipal Investigator

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FURUSE MIKIO 古瀬幹夫

Furuse Mikio 古瀬幹夫

FURUSE Mikio 古瀬幹夫