Kato Shinichi 加藤伸一

… Alternative Names

KATO Shinichi 加藤伸一

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Researcher Number	90281500
Other IDs
External Links
Affiliation (Current)	2025: 京都薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2023: 京都薬科大学, 薬学部, 教授 2013 – 2016: 京都薬科大学, 薬学部, 教授 2008 – 2010: Kyoto Pharmaceutical University, 薬学部, 准教授 2004 – 2007: 京都薬科大学, 薬学部, 講師 2003: Kyoto Pharmaceutical University, Pharmacology and Experimental Therapeutics, Assistant Professor, 薬学部・薬物治療学教室, 講師 … More 2003: 京都薬科大学, 薬物治療学教室, 講師 2000 – 2002: 京都薬科大学, 薬学部, 講師 1996 – 1999: 京都薬科大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Applied pharmacology / Basic Section 47040:Pharmacology-related / 応用薬理学・医療系薬学 / Pharmacology in pharmacy Except Principal Investigator 応用薬理学・医療系薬学 / Basic Section 49050:Bacteriology-related / Pharmacology in pharmacy / Applied pharmacology
Keywords	Principal Investigator マクロファージ / 一酸化窒素(NO) / 大腸炎 / 腸上皮バリア / 炎症性腸疾患 / サイトカイン / 誘導型NO合成酵素(iNOS) / 腸管マクロファージ / 内皮型NO合成酵素(eNOS) / 内皮型NO合成酵素 … More / 消化管傷害 / 非ステロイド性抗炎症薬(NSAID) / 非ステロイド系抗炎症薬 / プロスタグランジン / 胃粘膜 / 大腸がん / 難治性腸疾患 / デキストラン硫酸ナトリウム誘起大腸炎 / 細胞間結合タンパク質 / TRPV6 / 線維化 / 大腸炎関連がん / Gタンパク質共役型受容体 / 小腸傷害 / ロドキサミド / タイトジャンクション / 粘液 / タイトジャンクション関連タンパク質 / 粘液分泌 / GPR35 / macrophage / toll-like receptor 4(TLR4) / endothelial NO svnthase(eNOS) / inducible NO svnthase(iNOS) / nitric oxide(NO) / gastrointestinal iniury / non-steroidal anti-inflammatory drug / adjvant arthritic rat / シクロオキシゲナーゼ(COX) / 小腸粘膜障害 / 胃粘膜傷害 / 一酸化窒素合成酵素(NOS) / リウマチ性関節炎 / Toll-like receptor 4(TLR4) / 非ステロイド性抗炎症薬 / アジュバント関節炎ラット / ケモカイン / 消化管炎症 / 活性酸素 / NOX1 / 小腸障害傷害 / α7ニコチンアセチルコリン受容体 / 一酸化窒素 / 消化管マクロファージ / α7ニコチン性アセチルコリン受容体 / 酸逆流性食道炎 / 腸クロム親和性様細胞 / ヒスタミン / EP受容体 / ペプシン分泌 / 胃酸分泌 / 繊維芽細胞増殖因子 / 慢性潰瘍 / 線維芽細胞増殖因子 / アジュバント関節炎 / COX-2選択的阻害薬 / 非ステロイド傾向炎症薬 / ヘリコバクターピロリ / 治癒 / 損傷 / モノクロラミン / アンモニア … More Except Principal Investigator 一酸化窒素 / nitric oxide / 粘膜血流 / プロスタグランジン / インフルエンザ菌 / 細菌性肺炎 / ガン転移 / 肺炎球菌 / TLR4/MD-2受容体 / 水様性ビザンチン / 機能性糖脂質 / エンドトキシンショック / TLR4/MD2 / 皮膚疾患 / ビザンチン / LPS / ミュータンス菌 / 肺炎 / バイオフィルム / ベン毛 / 緑膿菌 / 水溶性糖脂質 / 薬剤耐性菌 / cytoprotection / RGM1 / bicarbonate secretion / EP receptor subtype / gastric protection / vanilloid receptor type 1 / capsaicin / Capsaicin-sensitive afferent neuron / 胃粘膜血流 / 十二指腸アルカリ分泌 / IP受容体 / EP / 胃粘膜保護作用 / バニロイド受容体 / カプサイシン / protection / microsphere capsule / colonic delivery / ulcerative colitis / ellagic acid / polyphenol / 抗酸化作用 / モノクロラミン胃損傷 / 炎症性病変 / 保護効果 / 圧感応性カプセル / 大腸デリバリー / 潰瘍性大腸炎 / エラグ酸 / ポリフェノール / small intestinal lesion / gastric lesion / indomethacin / USAIDs / 損傷治癒 / 胃粘膜傷害性 / NO遊離型アスピリン / 小腸損傷 / 胃損傷 / 関節炎モデル / インドメタシン / 非ステロイド系抗炎症薬 / capsaicin-sensitive sensory neuron / histamine / mucosal mast cell / luminal Ca^<2+> / acid secretion / stomach / surface epithelial damage / 修復機転 / 酸分泌抑制 / 知覚神経 / ヒスタミン / 管腔内Ca / 酸分泌変化 / 傷害発生 / 胃粘膜 / グルタミン酸 / ヘリコバクターピロリ関連胃疾患 / Helicobacter pylori / 小腸傷害 / 胃潰瘍 / 胃粘膜傷害 / COX-2 / COX-1 / NSAIDs Less

Roles of Ca2+-permeable TRPV6 in the regulation of intestinal epithelial barrier functionsPrincipal Investigator
- Principal Investigator
  
  加藤伸一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kyoto Pharmaceutical University
Elucidation of the pathogenic role of orphan G protein coupled recepor GPR35 in inflammatory bowel diseaesesPrincipal Investigator
- Principal Investigator
  
  Kato Shinichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kyoto Pharmaceutical University
Elucidation of effectiveness and mechanism of new water-soluble glycolipids in bacterial pneumonia control
- Principal Investigator
  
  Oda Masataka
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kyoto Pharmaceutical University
Ameliorative effect of glutamate on Helicobacter pylori-related gastropathy
- Principal Investigator
  
  Amagase Kikuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Understanding for the pathogenic mechanisms of NOX1 expressed in macrophages in intestinal inflammationPrincipal Investigator
- Principal Investigator
  
  Kato Shinichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Role of intestinal macrophages in the pathogenesis of intestinal lesions induced by non-steroidal anti-inflammatory drugs.Principal Investigator
- Principal Investigator
  
  KATO Shinichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto Pharmaceutical University
Mechanism elucidation for the aggravation of gastrointestinal injury induced by non-steroidal anti-inflammatory drugs during chronic arthritis.Principal Investigator
- Principal Investigator
  
  KATO Shinichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto Pharmaceutical University
胃酸およびペプシン分泌調節におけるプロスタグランジンE/EP受容体の役割Principal Investigator
- Principal Investigator
  
  加藤伸一
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto Pharmaceutical University
非ステロイド系抗炎症薬(NSAIDs)による胃腸傷害の発生とCOX阻害との関連性-COX-1阻害により誘導されるCOX-2の役割と誘導機序-
- Principal Investigator
  
  TANAKA Akiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto Pharmaceutical University
Distribution of vanilloid receptors (VR1) in gastrointestinal tract and their role in mucosal protection mediated by capsaicin-sensitive afferent neurons
- Principal Investigator
  
  TAKEUCHI Koji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
慢性関節炎発症時における消化管障害性ならびに治癒反応の変化Principal Investigator
- Principal Investigator
  
  加藤伸一
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
Protection against dextran sulfate sodium-induced colitis by microsheres of polyphenol (ellagic acid)
- Principal Investigator
  
  TAKEUCHI Koji
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for University and Society Collaboration
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
ヘリコバクター・ピロリ産生アンモニア-モノクロラミンの胃粘膜に対する影響Principal Investigator
- Principal Investigator
  
  加藤伸一
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
Development of NSAIDs that spare gastrointestinal tract injury.-COX-2 selective and NO-releasing NSAIDs-
- Principal Investigator
  
  TAKEUCHI Koji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University
Regulatory mechanism of acid secretory response in the stomach following injury : Role of nitric oxide.
- Principal Investigator
  
  TAKEUCHI Koji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kyoto Pharmaceutical University

All 2023 2022 2017 2016 2015 2014 2013 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Lafutidine, a histamine H2 receptor antagonist with mucosal protective properties, attenuates 5-fluorouracil-induced intestinal mucositis in mice through activation of extrinsic primary afferent neurons.2017
- Author(s)
  Sano T, Utsumi D, Amagase K, Matsumoto K, Tominaga M, Higuchi K, Takeuchi T, Kato S.
- Journal Title
  
  J Physiol Pharmacol.
  
  Volume: 68 Pages: 79-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460109
[Journal Article] Apoptosis, Dysbiosis and Expression of Inflammatory Cytokines are Sequential Events in the Development of 5-Fluorouracil-induced Intestinal Mucositis in Mice.2017
- Author(s)
  Hamouda N, Sano T, Oikawa Y, Ozaki T, Shimakawa M, Matsumoto K, Amagase K, Higuchi K, Kato S.
- Journal Title
  
  Basic Clin Pharmacol Toxicol.
  
  Volume: in press Issue: 3 Pages: 159-168
- DOI
  10.1111/bcpt.12793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460109
[Journal Article] Role of NADPH oxidase 1 (NOX1) in gut inflammation2016
- Author(s)
  加藤伸一
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 147 Issue: 1 Pages: 18-22
- DOI
  10.1254/fpj.147.18
- NAID
  130005118584
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460110
[Journal Article] Serotonin/5-hydroxytryptamine-3 receptors promote colonic inflammation via activation of substance P/neurokinin-1 receptors in dextran sulphate sodium-induced murine colitis2016
- Author(s)
  Utsumi D, Matsumoto K, Amagase K, Horie S, Kato S.
- Journal Title
  
  Br. J. Pharmacol.,
  
  Volume: 173 Issue: 11 Pages: 1835-1849
- DOI
  10.1111/bph.13482
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07968, KAKENHI-PROJECT-24590118, KAKENHI-PROJECT-25460110, KAKENHI-PROJECT-25860395
[Journal Article] Glutamate as a Potential Protective Drug in the Gastrointestinal Mucosa2015
- Author(s)
  天ヶ瀬紀久子、中村英志、加藤伸一、竹内孝治
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 135 Issue: 6 Pages: 779-782
- DOI
  10.1248/yakushi.14-00250-3
- NAID
  130005071775
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2015-06-01
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-26460109
[Journal Article] Saireito (TJ-114), a Japanese traditional herbal medicine, reduces 5-fluorouracil-induced intestinal mucositis in mice by inhibiting cytokine-mediated apoptosis in intestinal crypt cells.2015
- Author(s)
  Kato S, Hayashi, S, Kitahara Y, Nagasawa K, Aono H, Shibata J, Utsumi D, Amagase K, Kadowaki M
- Journal Title
  
  Plos One
  
  Volume: 10 Issue: 1 Pages: e0116213-e0116213
- DOI
  10.1371/journal.pone.0116213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460110
[Journal Article] Activation of α7 nicotinic acetylcholine receptors ameliorates indomethacin-induced small intestinal ulceration in mice2011
- Author(s)
  Kawahara R, Yasuda M, Hashimura H, Amagase K, Kato S, Takeuchi K
- Journal Title
  
  European Journal of Pharmacology 650
  
  Pages: 248-261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590550
[Journal Article] Prevention by lansoprazole, a proton pump inhibitor, of indomethacin-induced small intestinal ulceration in rats through induction of heme oxygenase-1.2010
- Author(s)
  Yoda Y, Amagase K, Kato S, Tokita S, Murano K, Kakimoto H, Nishio H, Umegaki E, Takeuchi K, Higuchi K.
- Journal Title
  
  Journal of Physiology and Pharmacology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590550
[Journal Article] Roles of COX inhibition in pathogenesis of NSAID-induced small intestinal damage.2010
- Author(s)
  Takeuchi K, Tanaka A, Kato S, Amagase K, Satoh H.
- Journal Title
  
  Clinica Chimica Acta 411
  
  Pages: 459-466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590550
[Journal Article] Prevention by lansoprazole, a proton pump inhibitor, of indomethacin-induced small intestinal ulceration in rats.2010
- Author(s)
  Yoda Y, Amagase K, Kato S, Tokioka S, Murano M, Kakimoto K, Nishio H, Umegaki E, Takeuchi K, Higuchi K.
- Journal Title
  
  Journal of Physiology and Pharmacology 61
  
  Pages: 287-294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590550
[Journal Article] Roles of COX inhibition in pathogenesis of NSAID-induced small intestinal damage2010
- Author(s)
  Takeuchi K, Tanaka A, Kato S, Amagase K, Satoh H
- Journal Title
  
  Clinica Chimica Acta 411
  
  Pages: 459-466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590550
[Journal Article] Roles of nitric oxide synthase in aggravation of indomethacin-induced gastric damage in adjuvant arthritic rats.2009
- Author(s)
  Kato S, Ohkawa F, Ito Y, Amagase K, Takeuchi K.
- Journal Title
  
  Journal of Physiology and Pharmacology 60
  
  Pages: 147-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590550
[Journal Article] Aggravation of cold-restraint stress-induced gastric lesions in adjuvant arthritic rats : pathogenic role of inducible and endothelial nitric oxide.2009
- Author(s)
  Kato S, Kawahara R, Yasuda M, Amagase K, Takeuchi K.
- Journal Title
  
  Journal of Pharmacological Sciences 111
  
  Pages: 244-252
- NAID
  10026154083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590550
[Journal Article] Role of endothelial nitric oxide synthase in aggravation of indomethacin-induced gastric damage in adjuvant arthritic rats.2009
- Author(s)
  Kato S, Ohkawa F, Ito Y, Takeuchi K.
- Journal Title
  
  Journal of Physiology and Pharmacology 60
  
  Pages: 147-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590550
[Journal Article] Sildenafil, an inhibitor of phosphodiesterase subtype 5, prevents indomethacin-induced small intestinal ulceration in rats via a NO/cGMP-dependent mechanism.2009
- Author(s)
  Kato N, Mashita Y, Kato S, Mitsufuji S, Yoshikawa T, Takeuchi K.
- Journal Title
  
  Digestive Diseases and Sciences (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590550
[Journal Article] Roles of nitric oxide (NO) and NO synthase in healing of dextran sulfate sodium-induced rat colitis.2008
- Author(s)
  Aoi Y, Terashima S, Ogura M, Nishio H, Kato S, Takeuchi K
- Journal Title
  
  Journal of Physiology and Pharmacology 59
  
  Pages: 886-892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590550
[Journal Article] Aggravation of selective COX-1 and COX-2 inhibitors of dextran sulfate sodium (DSS)-induced colon lesion in rats2007
- Author(s)
  Okayama M, Hayashi S, Aoi Y, Nishio H, Kato S, Takeuchi K
- Journal Title
  
  Digestive Diseases and Sciences 52
  
  Pages: 2095-2103
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Increased susceptibility of small intestine to NSAID-provoked ulceration in rats with adjuvant-induced arthritis : involvement of enhanced expression of TLR4.2007
- Author(s)
  Kato S, Nishio H, Aoi Y, Amagase K, Takeuchi K
- Journal Title
  
  Life Sciences(peer review) 81
  
  Pages: 1309-1316
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Increased susceptibility of small intestine to NSAID-provoked ulceration in rats with adjuvant-induced arthritis:involvement of enhanced expression of TLR42007
- Author(s)
  Kato S, Ito Y, Nishio H, Aoi Y, Amagase K, Takeuchi K
- Journal Title
  
  Life Sciences 81
  
  Pages: 1309-1316
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Increased susceptibility of small intestine to NSAID-provoked ulceration in rats with adjuvant-induced arthritis:involvement of enhanced expression of TLR42007
- Author(s)
  Kato S, Ito Y, Nishio H, AoiY, Amagase K, Takeuchi K
- Journal Title
  
  Life Sciences 81
  
  Pages: 1309-1316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Tacrolimus (FK506), an immunosuppressive agent, prevents indomethacin-induced small intestinal ulceration in the rat : inhibition of inducible nitric oxide synthase expression.2007
- Author(s)
  Kato S, Nishio H, Ogura M, Takeuchi K.
- Journal Title
  
  Jornal of Pharmacological Science 103・1
  
  Pages: 40-47
- NAID
  10024311915
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcersvia EP4 receptors2007
- Author(s)
  Hatazawa R, Tanaka A, Tanigami M, Amagase K, Kato S, Ashida Y, Takeuchi K
- Journal Title
  
  American Journal of Physiology 293
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcers Via EP4 receptors.2007
- Author(s)
  Hatazawa R, Tanaka A, Tanigami M, Amagase K, Kato S, Takeuchi K
- Journal Title
  
  American Journal of Physiology(pee review) 293
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcersvia EP4 receptors.2007
- Author(s)
  Hatazawa R, Tanaka A, Tanigami M, Amagase K, Kato S, Ashida Y, Takeuchi K
- Journal Title
  
  American Journa of Physiology 293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Effect of(S)-4-(1-(5-chloro-2-(4-fluorophenyoxy) benzamido) ethyl) benzoic acid(CJ-42794), a selective antagonist of prostaglandin E receptor subtype 4, on ulcerogenic and healing responses in ratgastrointestinal mucosa.2007
- Author(s)
  Takeuchi K, Tanaka A, Kato S, Aihara E, Amagase K
- Journal Title
  
  Journal of Pharmacology of Experimental Therapeutics(peer review) 322
  
  Pages: 903-912
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Aggravation of selective COX-1 and COX-2 inhibitors of dextran sulfate sodium(DSS)-induced colon lesions in rats.2007
- Author(s)
  Okayama M, Hayashi S, Aoi Y, Nishio H, Kato S, Takeuchi K
- Journal Title
  
  Digestive Disease and Sciences(peer review) 52
  
  Pages: 2095-2103
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Effect of (S)-4-(1-(5-chloro-2-(4-fluorophenyoxy)benzamido)ethyl) benzoicacid (CJ-42794),a selective antagonist of prostaglandin E receptor subtype 4,on ulcerogenic and healing responses in rat gastrointestinal mucosa2007
- Author(s)
  Takeuchi K, Tanaka A, Kato S, Aihara E, Amagase K
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 322
  
  Pages: 903-912
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Effect of (S)-4-(1-(5-chloro-2-(4-fluorophenyoxy)bezamido)ethyl)benzoicacid(CJ-42794),a selective antagonist of prostaglandin E receptor subtype 4,on ulcerogenic and healing responses in rat gastrointestinal mucosa2007
- Author(s)
  Takeuchi K, Tanaka A, Kato S, Aihara E, Amagase K
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 322
  
  Pages: 903-912
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Tacrolimus(FK506), an immuno-suppressive agent, prevents indomethacin-induced small intestinal ulceration in rats : inhibition of inducible nitric oxide synthase expression.2007
- Author(s)
  Kato S, Nishio H, Ogura M, Takeuchi K
- Journal Title
  
  Journal of Pharmacological Sciences(peer review) 103
  
  Pages: 40-47
- NAID
  10024311915
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Tacrolimus (FK506),an immunosuppressive agent,prevents indomethacin-induced small intestinal ulceration in rats: inhibition of inducible nitric oxide synthase expression2007
- Author(s)
  Kato S, Nishio H, Ogura M, Takeuchi K
- Journal Title
  
  Journal of Pharmacological Sciences 103
  
  Pages: 40-47
- NAID
  10024311915
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Pathogenic role of endothelial nitric oxide synthase (eNOS/NOS-III) in caerulein-induced rat acute pancreatitis.2006
- Author(s)
  Sugiyama Y, Kato S, Mitsufuji S, Okanoue T, Takeuchi K.
- Journal Title
  
  Digestive Diseases and Sciences 51・8
  
  Pages: 1396-1403
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] 慢性関節炎発症時における非ステロイド系抗炎症薬による消化管傷害性の変化2006
- Author(s)
  加藤伸一, 竹内孝治(総説)
- Journal Title
  
  日本薬理学雑誌 128・2
  
  Pages: 88-92
- NAID
  10018333208
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] 慢性関節炎ラットにおける非ステロイド性抗炎症薬による消化管傷害性の変化2006
- Author(s)
  加藤伸一、竹内孝治(総説)
- Journal Title
  
  日本薬理学雑誌 128
  
  Pages: 88-92
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Changes in ulcerogenic response to non-steroidal anti-inflammatory drugs(NSAID) in the gastrointestine during chronic arthritis.2006
- Author(s)
  Kato S, Takeuchi K
- Journal Title
  
  Folia Pharmacologica Japonica(not peer review) 128
  
  Pages: 88-92
- NAID
  10018333208
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Healing impairement effect of cyclooxygenase inhibitors on dextran sulfate sodium-induced colitis in rats.2006
- Author(s)
  Tsubouchi R, Hayashi R, Aoi Y, Terashima S, Kato S, Takeuchi K.
- Journal Title
  
  Digestion 74・2
  
  Pages: 91-100
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Healing impairment effect of cyclooxygenase inhibitors on dextran sulfate sodium-induced colitis in rats2006
- Author(s)
  Tsubouchi R, Hayashi R, Aoi Y, Tashima K, Kato S, Takeuchi K
- Journal Title
  
  Digestion 74
  
  Pages: 91-100
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Healing impairment effect of cyclooxygenase inhibitors on dextran sulfate sodium-induced colitis in rats.2006
- Author(s)
  Tsubouchi R, Hayashi S, Aoi Y, Tashima K, Kato S, Takeuchi K
- Journal Title
  
  Digestion(peer review) 74
  
  Pages: 91-100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Pathogenic role of endothelial nitric oxide synthase (eNOS/NOS-III) in caerulein-induced rat acute rat acute pancreatitis2006
- Author(s)
  Sugiyama Y, Kato S, Mitsufuji S, Okanoue T, Takeuchi K
- Journal Title
  
  Digestive Disease and Sciences 51
  
  Pages: 1396-1403
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Pathogenic role of endothelial nitric oxide synthase(eNOS/NOS-III) in caerulein-induced rat acute pancreatitis.2006
- Author(s)
  Sugiyama Y. Kato S. Mitsufuji S. Okanoue T. Takeuchi K
- Journal Title
  
  Digestive Disease and Sciences(peer review) 51
  
  Pages: 1396-1403
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Journal Article] Dual action of prostaglandin E2 on gastric acid secretion through different EP receptor subtypes in the rat.2005
- Author(s)
  Shinichi Kato
- Journal Title
  
  American Journal of Physiology (In press)
- Data Source
  KAKENHI-PROJECT-16790312
[Journal Article] Dual action of prostaglandin E2 on gastric acid secretion through EP-receptor subtypes in the rat2005
- Author(s)
  加藤伸一
- Journal Title
  
  American Journal of Physiology 289・1
- Data Source
  KAKENHI-PROJECT-16790312
[Presentation] Ca2+高透過性TRPV6の粘膜バリア機能の調節を介した大腸炎に対する保護的役割2023
- Author(s)
  田嶋鈴夏、安田浩之、斉藤美知子、松本健次郎、加藤伸一
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K06158
[Presentation] オーファンGタンパク質共役型受容体GPR35の腸炎における抗炎症的役割2022
- Author(s)
  元川典子、杤岡実思、杉本彩貴、徳山珖雅、榎原梨華、斉藤美知子、安田浩之、松本健次郎、加藤伸一
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07078
[Presentation] オーファンGタンパク質共役型受容体GPR35の腸炎の病態における役割2022
- Author(s)
  徳山珖雅、橘　佑輔、岸　采花、村瀬由衣、安田浩之、斉藤美知子、松本健次郎、加藤伸一
- Organizer
  生体機能と創薬シンポジウム2022（静岡）
- Data Source
  KAKENHI-PROJECT-20K07078
[Presentation] Orphan G protein-coupled receptor GPR35 contributes to the pathogenesis of dextran sulfate sodium-induced colitis in mice2022
- Author(s)
  Ayaka Kishi, Yusuke Tachibana, Yui Murase, Koga Tokuyama, Michiko Saito, Hiroyuki Yasuda, Kenjiro Matsumoto, Shinichi Kato
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07078
[Presentation] オーファンGタンパク質共役型受容体GPR35の腸炎に対する保護的役割2022
- Author(s)
  杤岡実思、元川典子、杉本彩貴、徳山珖雅、榎原梨華、斉藤美知子、安田浩之、松本健次郎、加藤伸一
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07078
[Presentation] Helicobacter pylori誘起胃粘膜病変に対するグルタミン酸の保護効果2017
- Author(s)
  加納嘉太郎、北居香菜子、宗本尚子、中井千秋、松本健次郎、天ヶ瀬紀久子、加藤伸一
- Organizer
  日本薬学会第137年会
- Place of Presentation
  宮城県（仙台）
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-26460109
[Presentation] グルタミンおよびグルタミン酸の薬剤起因性消化管傷害に対する保護効果2016
- Author(s)
  天ヶ瀬紀久子、岡田沙知、加納嘉太郎、松本健次郎、加藤伸一
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-26460109
[Presentation] Helicobacter pylori誘起胃粘膜病変に対するグルタミン酸の保護効果2015
- Author(s)
  天ヶ瀬紀久子、播磨弘樹、山崎華步、中村英志、竹内孝治、松本健次郎、加藤伸一
- Organizer
  第33回サイトプロテクション研究会
- Place of Presentation
  メルバルク京都（京都府・京都市）
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-26460109
[Presentation] 炎症性腸疾患の病態におけるNOX1/NADPH oxidase の役割2015
- Author(s)
  續木彩香、島田裕規、今井梓嵯、岩田和美、矢部千尋、加藤伸一
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2015
- Place of Presentation
  東京
- Year and Date
  2015-08-29
- Data Source
  KAKENHI-PROJECT-25460110
[Presentation] 炎症性腸疾患の病態におけるNADPH oxdase 1（NOX1）の役割2015
- Author(s)
  加藤伸一
- Organizer
  第88回日本薬理学会年会　シンポジウム24
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-19
- Invited
- Data Source
  KAKENHI-PROJECT-25460110
[Presentation] Serotonin/5-HT3 receptor and substance P/NK1 receptor pathways contribute to the pathogenesis of colonis inflammation in mice.2015
- Author(s)
  Daichi Utsumi, Kenjiro Matsumoto, Kikuko Amagase, Shinichi Kato
- Organizer
  Digestive Disease Week 2015
- Place of Presentation
  Washington DC, USA
- Year and Date
  2015-05-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460110
[Presentation] NADPH Oxidase 1 (NOX1) Expressed in Colonic Macrophages Plays a Crucial Role in Trinitrobenzene Sulfonic Acid (TNBS)-Induced Colonic Inflammation in Mice.2014
- Author(s)
  Haruka Yokota, Daichi Utsumi, Hiroyo Nakajima, Riho Tanaka, Mari Yamada, Yuya Tanaka, Kikuko Amagase, Shinichi Kato
- Organizer
  Digestive Diseases Week 2014
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-25460110
[Presentation] トリニトロベンゼンスルホン酸(TNBS)誘起大腸炎の病態における NADPH oxidase 1 (NOX1)の役割2014
- Author(s)
  今井梓嵯、上田伸幸、横田遥1、岩田和実、松本健次郎、天ヶ瀬紀久子、矢部千尋、加藤伸一
- Organizer
  生体機能と創薬シンポジウム2014
- Place of Presentation
  近畿大学
- Year and Date
  2014-08-28
- Data Source
  KAKENHI-PROJECT-25460110
[Presentation] トリニトロベンゼンスルホン酸（TNBS）誘起大腸炎の病態におけるNADPH oxidase1(NOX1)の役割2013
- Author(s)
  加藤伸一、天ヶ瀬紀久子、竹内孝治
- Organizer
  日本潰瘍学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25460110
[Presentation] α7ニコチン受容体活性化によるインドメタシン誘起小腸傷害の抑制2011
- Author(s)
  河原良治、安田仁、橋村寛、天ヶ瀬紀久子、加藤伸一、竹内孝治
- Organizer
  第7回日本消化管学会学術集会
- Place of Presentation
  京都
- Year and Date
  2011-02-18
- Data Source
  KAKENHI-PROJECT-20590550
[Presentation] Different mechanisms of effective PPIs or H2-blockers for prevention of NSAID-induced small intestinal damage.2010
- Author(s)
  Yoda Y, Amagase K, Kato S, Tokioka S, Murano M, Kakimoto K, Takeuchi K, Higuchi K.
- Organizer
  米国消化器病学会
- Place of Presentation
  米国ニューオリンズ
- Year and Date
  2010-05-03
- Data Source
  KAKENHI-PROJECT-20590550
[Presentation] α7ニコチン受容体活性化によるインドメタシン誘起小腸傷害の抑制2010
- Author(s)
  河原良治、安田仁、天ヶ瀬紀久子、加藤伸一、竹内孝治
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-20590550
[Presentation] α7ニコチン受容体活性化によるインドメタシン誘起小腸傷害の抑制効果2010
- Author(s)
  河原良治、安田仁、天ヶ瀬紀久子、加藤伸一、竹内孝治
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-20590550
[Presentation] アジュバント関節炎ラットにおけるインドメタシン誘起胃損傷の増悪 : 内皮型一酸化窒素合成酵素(eNOS)の関与2009
- Author(s)
  加藤伸一, 大川文一, 伊藤泰行, 天ヶ瀬紀久子, 竹内孝治
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20590550
[Presentation] Increased susceptibility of small intestine to non-steroidal anti-inflammatory drug (NSAID)-provoked ulceration in rats with adjuvant-induced arthritis involvement of increased expression of toll-like receptor (TLR)42008
- Author(s)
  Kato S
- Organizer
  Symposium on Recent Advances in Gastrointestinal Pharmacology and Nutrigenomics
- Place of Presentation
  Seoul,Korea
- Year and Date
  2008-02-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Presentation] 非ステロイド性抗炎症薬(NSAID)誘起小腸傷害の病態生理:関節炎発症時における小腸傷害の増悪2008
- Author(s)
  加藤伸一、天ケ瀬紀久子、竹内孝治
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Presentation] Increased susceptibility of small intestine to non-steroidal anti-inflammatory drug(NSAID)-provoked ulceration in rats with adjuvant-induced arthritis : involvement of increased expression of toll-like receptor(TLR) 4.2008
- Author(s)
  Kato S.
- Organizer
  Symposium of Recent Advances in Gstrointestinal Pharmacology and Nutrigenomics
- Place of Presentation
  Seoul Korea
- Year and Date
  2008-02-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Presentation] Pathogenic mechanism of NSAID-induced small intestinal ulceration in normal and arthritic rats.2008
- Author(s)
  Kato S, Amagase K, Takeuchi K
- Organizer
  The 81st Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Yokohama
- Year and Date
  2008-03-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Presentation] Aggravation of indomethacin induced small intestinal ulceration in adjuvant-induced arthritis: involvement of toll-like receptor(TLR)-4.2007
- Author(s)
  Kato S, Nishio H, Amagase K, Takeuchi K
- Organizer
  The 3rd Annual Meeting of The Japanese Gastroenterological Association
- Place of Presentation
  Tokyo
- Year and Date
  2007-02-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Presentation] アジュバント関節炎ラットにおけるインドメタシン誘起小腸傷害の増悪:Toll-like receptor(TLR)-4の関与2007
- Author(s)
  加藤伸一、西尾光、天ケ瀬紀久子、竹内孝治
- Organizer
  第3回日本消化管学会学術集会
- Place of Presentation
  東京
- Year and Date
  2007-02-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Presentation] Changes in intestinal ulcerogenic response to NSAID during arthritis : involvement of iNOS and toll-like receptor 4(TLR4).2007
- Author(s)
  Kato S, Ito Y, Nishio H, Amagase K, Takeuchi K
- Organizer
  The 35th Annual Meeting of The Japanese Society of Ulcer Research
- Place of Presentation
  Tottori
- Year and Date
  2007-09-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Presentation] 関節炎発症時におけるNSAID誘起小腸傷害性の変化:iNOSおよびToll-like receptor 4(TLR4)の関与2007
- Author(s)
  加藤伸一、伊藤泰行、西尾光、天ケ瀬紀久子、竹内孝治
- Organizer
  第35回日本潰瘍学会
- Place of Presentation
  鳥取
- Year and Date
  2007-09-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590518
[Presentation] NADPH oxidase (NOX1) expressed in colonic macrophages plays a crucial role in trinitrobenzene sulfonic acid (TNBS)-induced clonic inflammation in mice.
- Author(s)
  Yokota, H, Utsumi D, Nakajima H, Tanaka R, Yamada M, Tanaka Y, Amagase K, Kato S
- Organizer
  Digestive Diseases Week 2014
- Place of Presentation
  Chicago, USA
- Year and Date
  2014-05-03 – 2014-05-06
- Data Source
  KAKENHI-PROJECT-25460110

1. TAKEUCHI Koji (00150798)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. TANAKA Akiko (30329940)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. IWATA Kazumi (60305571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. Amagase Kikuko (60278447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. SHIBATA Nobuhito (60319449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TAKADA Kanji (30102106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YOSHIKAWA Yukako (30278444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Oda Masataka (00412403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 栄田敏之 (00304098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 林直樹 (70707463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KANOU Yoshitaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. KITAI Kanako

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 堀江俊治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kato Shinichi 加藤 伸一

KATO Shinichi 加藤 伸一

Research Projects

Research Products

Co-Researchers

Roles of Ca2+-permeable TRPV6 in the regulation of intestinal epithelial barrier functionsPrincipal Investigator

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Elucidation of the pathogenic role of orphan G protein coupled recepor GPR35 in inflammatory bowel diseaesesPrincipal Investigator

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Elucidation of effectiveness and mechanism of new water-soluble glycolipids in bacterial pneumonia control

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Review Section

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Ameliorative effect of glutamate on Helicobacter pylori-related gastropathy

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Understanding for the pathogenic mechanisms of NOX1 expressed in macrophages in intestinal inflammationPrincipal Investigator

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Role of intestinal macrophages in the pathogenesis of intestinal lesions induced by non-steroidal anti-inflammatory drugs.Principal Investigator

Principal Investigator

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Mechanism elucidation for the aggravation of gastrointestinal injury induced by non-steroidal anti-inflammatory drugs during chronic arthritis.Principal Investigator

Principal Investigator

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胃酸およびペプシン分泌調節におけるプロスタグランジンE/EP受容体の役割Principal Investigator

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非ステロイド系抗炎症薬(NSAIDs)による胃腸傷害の発生とCOX阻害との関連性-COX-1阻害により誘導されるCOX-2の役割と誘導機序-

Principal Investigator

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Distribution of vanilloid receptors (VR1) in gastrointestinal tract and their role in mucosal protection mediated by capsaicin-sensitive afferent neurons

Principal Investigator

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慢性関節炎発症時における消化管障害性ならびに治癒反応の変化Principal Investigator

Principal Investigator

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Protection against dextran sulfate sodium-induced colitis by microsheres of polyphenol (ellagic acid)

Principal Investigator

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ヘリコバクター・ピロリ産生アンモニア-モノクロラミンの胃粘膜に対する影響Principal Investigator

Principal Investigator

Project Period (FY)

Kato Shinichi 加藤伸一

KATO Shinichi 加藤伸一