Murai Shin 村井晋

… Alternative Names

村井晋ムライシン

MURAI Shin 村井晋

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Researcher Number	90287540
Other IDs
Affiliation (Current)	2025: 東邦大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2024: 東邦大学, 医学部, 講師 2020 – 2022: 東邦大学, 医学部, 助教 2016 – 2018: 東邦大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Basic Section 27040:Biofunction and bioprocess engineering-related / Biomedical engineering/Biomaterial science and engineering Except Principal Investigator Biomedical structure and function and related fields
Keywords	Principal Investigator 生体イメージング / 計画的ネクローシス / ネクロプトーシス / FRET / RIPK3 / DAMPs / 腎障害モデル / FRETバイオセンサー / in vivoイメージング / 急性腎疾患 … More / 敗血症 / FRETイメージング / ライブセルイメージング / 1分子FRET / １分子FRET / LCI-S / HMGB1 / Necroptosis / MLKL … More Except Principal Investigator Histone H3 / HMGB1 / ２光子顕微鏡 / SMART / トランスジェニックマウス / 全反射顕微鏡 / MLKL / RIPK3 / DAMPs / イメージング / FRET / ネクロプトーシス Less

Spatiotemporal analysis of immune cell infiltration through the DAMPs releasePrincipal Investigator
- Principal Investigator
  
  村井晋
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Toho University
FRET imaging of regulated necrosis in mouse sepsis modelPrincipal Investigator
- Principal Investigator
  
  Murai Shin
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Toho University
Live imaging of necroptosis and the release of DAMPs
- Principal Investigator
  
  NAKANO Hiroyasu
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biomedical structure and function and related fields
- Research Institution
  Toho University
Live cell imaging of regulated necrosisPrincipal Investigator
- Principal Investigator
  
  MURAI Shin
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Toho University

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis in male mice2023
- Author(s)
  Inaba Yuka、Hashiuchi Emi、Watanabe Hitoshi、Kimura Kumi、Oshima Yu、Tsuchiya Kohsuke et al.
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 167-167
- DOI
  10.1038/s41467-023-35804-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19426, KAKENHI-PROJECT-22K19545, KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-20K05238, KAKENHI-PROJECT-20K08860, KAKENHI-PROJECT-23K24764, KAKENHI-PROJECT-20H03509, KAKENHI-PROJECT-21H02695, KAKENHI-PROJECT-23K24390
[Journal Article] Regulation of the release of damage-associated molecular patterns from necroptotic cells2022
- Author(s)
  Nakano Hiroyasu、Murai Shin、Moriwaki Kenta
- Journal Title
  
  Biochemical Journal
  
  Volume: 479 Issue: 5 Pages: 677-685
- DOI
  10.1042/bcj20210604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07399, KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-20K05238
[Journal Article] Generation of transgenic mice expressing a FRET biosensor, SMART, that responds to necroptosis2022
- Author(s)
  Murai Shin、Takakura Kanako、Sumiyama Kenta、Moriwaki Kenta、Terai Kenta、Komazawa-Sakon Sachiko、Seki Takao、Yamaguchi Yoshifumi、Mikami Tetuo、Araki Kimi、Ohmuraya Masaki、Matsuda Michiyuki、Nakano Hiroyasu
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 1331-1331
- DOI
  10.1038/s42003-022-04300-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07997, KAKENHI-PLANNED-20H05766, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-21H02543, KAKENHI-PROJECT-20K05238, KAKENHI-PROJECT-23K21285, KAKENHI-PROJECT-23K21377, KAKENHI-PROJECT-23K24097
[Journal Article] MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL2021
- Author(s)
  Nakabayashi Osamu、Takahashi Hirotaka、Moriwaki Kenta、Komazawa-Sakon Sachiko、Ohtake Fumiaki、Murai Shin、Tsuchiya Yuichi、Koyahara Yuki、Saeki Yasushi、Yoshida Yukiko、Yamazaki Soh、Tokunaga Fuminori、Sawasaki Tatsuya、Nakano Hiroyasu
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 80-80
- DOI
  10.1038/s42003-020-01603-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07399, KAKENHI-PROJECT-19K07516, KAKENHI-PROJECT-20K05238, KAKENHI-PROJECT-20K06611, KAKENHI-PROJECT-20K11589, KAKENHI-PLANNED-16H06575, KAKENHI-PLANNED-16H06579, KAKENHI-PUBLICLY-19H05292, KAKENHI-PROJECT-19H02926, KAKENHI-PROJECT-19H03218, KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-20K09231, KAKENHI-PROJECT-19K22541, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-17H03986, KAKENHI-PROJECT-18H02619, KAKENHI-ORGANIZER-18H05497, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-16H06276
[Journal Article] Time-Lapse Imaging of Necroptosis and DAMP Release at Single-Cell Resolution2021
- Author(s)
  Murai Shin、Shirasaki Yoshitaka、Nakano Hiroyasu
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2274 Pages: 353-363
- DOI
  10.1007/978-1-0716-1258-3_29
- ISBN
  9781071612576, 9781071612583
- Data Source
  KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-20K05238
[Journal Article] Identification of the hallmarks of necroptosis and ferroptosis by transmission electron microscopy2020
- Author(s)
  Miyake Sanae、Murai Shin、Kakuta Soichiro、Uchiyama Yasuo、Nakano Hiroyasu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: - Issue: 3 Pages: 839-844
- DOI
  10.1016/j.bbrc.2020.04.127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-20K05238, KAKENHI-PROJECT-20H03475
[Journal Article] FRET解析とLCI-Sによるネクロプトーシスのライブセルイメージング2019
- Author(s)
  村井晋, 白崎義隆, 中野裕康
- Journal Title
  
  実験医学
  
  Volume: 37 Pages: 1315-1321
- Data Source
  KAKENHI-PROJECT-17K19533
[Journal Article] Development of novel methods that monitor necroptosis and the release of DAMPs at the single cell resolution2019
- Author(s)
  Nakano Hiroyasu、Murai Shin、Yamaguchi Yoshifumi、Shirasaki Yoshitaka、Nakabayashi Osamu、Yamazaki Soh
- Journal Title
  
  Cell Stress
  
  Volume: 3 Issue: 2 Pages: 66-69
- DOI
  10.15698/cst2019.02.177
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08994, KAKENHI-PUBLICLY-17H05496, KAKENHI-PLANNED-26110003, KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-16K01378, KAKENHI-PROJECT-16K08747, KAKENHI-PROJECT-17K19533, KAKENHI-PROJECT-19K07516
[Journal Article] A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs.2018
- Author(s)
  Murai S, Yamaguchi Y, Shirasaki Y, Yamagishi M, Shindo R, Hildebrand JM, Miura R, Nakabayashi O, Totsuka M, Tomida T, Adachi-Akahane S, Uemura S, Silke J, Yagita H, Miura M, Nakano H
- Journal Title
  
  Nat Commun
  
  Volume: 9 Issue: 1 Pages: 4457-4457
- DOI
  10.1038/s41467-018-06985-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06859, KAKENHI-PUBLICLY-17H05496, KAKENHI-PLANNED-26110003, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-16K01378, KAKENHI-PROJECT-17K19533, KAKENHI-PUBLICLY-17H06017, KAKENHI-PROJECT-16H06385, KAKENHI-PROJECT-16K07304
[Journal Article] Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome2016
- Author(s)
  Sakata, K. Araki, K. Nakano, H. Nishina, T. Komazawa-Sakon, S. Murai, S. Lee, G. E. Hashimoto, D. Suzuki, C. Uchiyama, Y. Notohara, K. Gukovskaya, A. S. Gukovsky, I. Yamamura, K. I. Baba, H. Ohmuraya, M.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 37200-37200
- DOI
  10.1038/srep37200
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26110003, KAKENHI-PROJECT-26460397, KAKENHI-PROJECT-16K01378, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-16K09398, KAKENHI-PROJECT-16K15681, KAKENHI-PROJECT-16H00591
[Presentation] MLKL mediates age-related attrition of hematopoietic stem cells and ineffective hematopoiesis in myelodysplastic syndrome2022
- Author(s)
  Yuta Yamada, Masayuki Yamashita, Jinjing Yang, Shin Murai, Kenta Sumiyama Hiroyasu Nakano, Atsushi Iwama
- Organizer
  64th ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05238
[Presentation] SMART Tgマウスを用いたネクロプトーシスのin vivoイメージングとDAMPs放出メカニズムの解析2022
- Author(s)
  村井晋
- Organizer
  第 3 回細胞死コロキウム
- Data Source
  KAKENHI-PROJECT-20K05238
[Presentation] SMART Tg マウスを用いた急性腎障害によるネクロプトーシスの in vivo FRET 解析2022
- Author(s)
  村井晋、隅山健太、森脇健太、高倉加奈子、山口良文、駒澤幸子、寺井健太、松田道行、中野裕康
- Organizer
  第30回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-20K05238
[Presentation] SMART Tgマウス由来細胞を用いたネクロプトーシスのライブセルイメージング2021
- Author(s)
  村井晋, 隅山健太, 森脇健太, 高倉加奈子, 山口良文, 駒澤幸子, 寺井健太, 三浦正幸, 松田道行, 中野裕康
- Organizer
  第29回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-20K05238
[Presentation] cFLIPのユビキチン化による新たなアポトーシス抑制機構の解析2020
- Author(s)
  中林修, 高橋宏隆, 村井晋, 大竹史明, 駒澤幸子, 土屋勇一, 佐伯泰, 吉田雪子, 山崎創, 徳永文稔, 森脇健太, 澤崎達也, 中野裕康
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K05238
[Presentation] ネクロプトーシスのタイムラプスイメージング2019
- Author(s)
  村井晋
- Organizer
  理研シンポジウム「細胞システムの動態と論理XI」
- Invited
- Data Source
  KAKENHI-PROJECT-16K01378
[Presentation] A Novel FRET Biosensor for Necroptosis Uncovers Two Different Modes of the Release of DAMPs2018
- Author(s)
  Shin Murai, Hiroyasu Nakano
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01378
[Presentation] FRETバイオセンサーによるネクロプトーシス実行の１細胞イメージング2018
- Author(s)
  村井晋, 山口良文, 白崎義隆, 進藤綾大, 中林修, Hildebrand Joanne, 冨田太一郎, 赤羽悟美, Silke John, 三浦正幸, 中野裕康
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K19533
[Presentation] FRETバイオセンサーによるネクロプトーシス実行の１細胞イメージング2018
- Author(s)
  村井晋, 山口良文, 白崎義隆, 進藤綾大, 中林修, Hildebrand Joanne, 冨田太一郎, 赤羽悟美, Silke John, 三浦正幸, 中野裕康
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K01378
[Presentation] A Novel FRET Biosensor for Necroptosis Uncovers Two Different Modes of the Release of DAMPs2018
- Author(s)
  Murai S, Nakano H
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19533
[Presentation] ネクロプトーシスをモニターするFRETバイオセンサーによるDAMPs放出メカニズムの解明2017
- Author(s)
  村井　晋、山口　良文、白崎　善隆、進藤　綾大、中林　修、三浦　亮介、冨田　太一郎†、赤羽　悟美、三浦　正幸、中野　裕康
- Organizer
  第40回日本分子生物学会年会　第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K19533
[Presentation] SMARTによるネクロプトーシス進行の継時的解析2017
- Author(s)
  村井　晋、白崎　善隆、山口　良文、冨田　太一郎、赤羽　悟美、三浦　正幸、中野　裕康
- Organizer
  第26回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-16K01378
[Presentation] SMARTによるネクロプトーシス進行の継時的解析2017
- Author(s)
  村井　晋、白崎　善隆、山口　良文、冨田　太一郎†、赤羽　悟美、三浦　正幸、中野　裕康
- Organizer
  第26回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-17K19533
[Presentation] 計画的ネクローシスをモニターするFRETバイオセンサーによるDAMPs放出メカニズムの解明2017
- Author(s)
  村井　晋、山口　良文、白崎　善隆、進藤　綾大、中林　修、三浦　亮介、冨田　太一郎、赤羽　悟美、三浦　正幸、中野　裕康
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K01378
[Presentation] １分子FRETによるネクロプトーシスのライブセルイメージング2017
- Author(s)
  村井　晋
- Organizer
  第4回Expert Seminar of Immunology
- Place of Presentation
  セルリアンタワー東急ホテル（東京都・渋谷区）
- Year and Date
  2017-05-22
- Invited
- Data Source
  KAKENHI-PROJECT-16K01378
[Presentation] ネクロプトーシスをモニターするFRETプローブの開発2016
- Author(s)
  村井　晋, 山口良文, 中林　修, 冨田　太一郎, 赤羽　悟美, 三浦正幸, 中野　裕康
- Organizer
  第25回　日本Cell Death学会学術集会
- Place of Presentation
  きゅりあん（東京都・品川区）
- Year and Date
  2016-09-09
- Data Source
  KAKENHI-PROJECT-16K01378

1. NAKANO Hiroyasu (70276476)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
2. YAMAGUCHI Yoshifumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. SHINDO Ryodai

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. NAKABAYASHI Osamu

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. YAMAZAKI Soh

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. OHMURAYA Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. TSUCHIYA Kohsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 赤羽悟美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 森脇健太

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Murai Shin 村井 晋

村井 晋 ムライ シン

MURAI Shin 村井 晋

Research Projects

Research Products

Co-Researchers

Spatiotemporal analysis of immune cell infiltration through the DAMPs releasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

FRET imaging of regulated necrosis in mouse sepsis modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Live imaging of necroptosis and the release of DAMPs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Live cell imaging of regulated necrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis in male mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of the release of damage-associated molecular patterns from necroptotic cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of transgenic mice expressing a FRET biosensor, SMART, that responds to necroptosis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Time-Lapse Imaging of Necroptosis and DAMP Release at Single-Cell Resolution2021

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Identification of the hallmarks of necroptosis and ferroptosis by transmission electron microscopy2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] FRET解析とLCI-Sによるネクロプトーシスのライブセルイメージング2019

Author(s)

Journal Title

Data Source

[Journal Article] Development of novel methods that monitor necroptosis and the release of DAMPs at the single cell resolution2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome2016

Author(s)

Journal Title

DOI

Data Source

Murai Shin 村井晋

村井晋ムライシン

MURAI Shin 村井晋