Morisaki Takashi 森崎隆

… Alternative Names

Researcher Number	90291517
Other IDs
External Links
Affiliation (Current)	2019: 九州大学, 医学研究院, 共同研究員
Affiliation (based on the past Project Information) *help	2015 – 2019: 九州大学, 医学研究院, 共同研究員 2012 – 2014: 九州大学, 医学(系)研究科(研究院), 共同研究員 2009 – 2011: Kyushu University, 大学院・医学研究院, 共同研究員 2007: Kyushu University, Faculty of Medical Sciences, Contracted Research Associate 2006: Kyushu University, Faculty of Medical Sciences, Contracted Research Associate, 大学院医学研究院, 非常勤講師 … More
Review Section/Research Field	Principal Investigator General surgery / General surgery / Digestive surgery / Basic Section 55040:Respiratory surgery-related Except Principal Investigator General surgery / Digestive surgery / Basic Section 55010:General surgery and pediatric surgery-related / General surgery / 内科学一般 / Digestive surgery
Keywords	Principal Investigator 免疫療法 / 樹状細胞 / 運動能 / 三次元培養 / 細胞障害活性 / 活性化リンパ球 / 大腸癌 / VEGF / バイオマーカー / 治療効果予測 … More Except Principal Investigator IFN-γ / 膵癌 / FR167653 / 制御性T細胞 / 癌性腹膜炎 / 免疫療法 / 樹状細胞 / 人工癌組織 / artificial connective tissue / 三次元培養 / 移植 / 人工結合織 / 人工血管 / gastric cancer / 腫瘍免疫 / 膵移植 / 機能分子 / エキソゾーム / 遺伝子導入 / Vaccine therapy / 人工リンパ節 / ワクチン療法 / Exosomes / OX40 / ischemia-reperfusion / 浸潤 / 人工腹膜 / HGF / アポトーシス / immunotherapy / artificial carcinoma tissue / Functional molecules / NK4 / 低重力培養 / サイトカイン / cytokine / 胃癌 / Dendritic cells / 転移 / TGF-β / 腎移植 / 抗腫瘍効果 / 特異的 / 免疫チェックポイント分子 / IL-4 / artifical peritoneum / Immunotherapy / 膵臓 / higher immune system / pancreas cancer / 分子標的治療 / artificial tissue / 免疫監視機構構築療法 / G2 / リンパ節 / 3-dimension / 低重力 / pathological examination / 細胞小体 / artificial lymphoid tissue / TGF-b / microgravity / artificial immyne organ / Presenilin-2 / Presenilin-1 / 伝達物質 / IL-2 / 癌性腹水 / peritoneal carcinosis / 早期癌 / Collagen / 腫瘍マーカー / γ-secretase / 免疫チェックポイント阻害薬 / Tumor mutational burden / 細胞間伝達 / Gene transfer / 腹膜播種モデル / Tumor Immunoloav / 蛋白分解酵素阻害剤 / Intercellular molecular transfer / HGF antagonist / ガンマセクレターゼ複合体 / Regulatory T cells / 細胞小胞 / pancreatic cancer / 細胞周期 / kidney transplantation / 細胞増殖 / 3次元培養 / Nicastrin / 腹膜 / 人工抗原 / 人工がん組織 / 高次免疫システム / 活性化リンパ球 / 虚血・再潅流障害 / GM-CSF / 腹膜移植 / SMAD / PTPN3 / g-secretase / HGFアンタゴニスト / pancreas / 大腸癌 / 細胞間分子移動 / tumor marker / 蛋白分解酵素 / warm ischemia / 中皮細胞 / peritoneal carcinomtosis / peritoneum / M集積 / 虚血再灌流障害 / 免役療法 / artificial peritoneum / 温疎血 / gene transfection / gamma secretase (GS)複合体 / INF-γ / 遺伝子治療 / 病理組織検査 / tumor immunity / 癌ワクチン療法 / Invasion / Pancreas / 早期膵癌 / Small vesicles / 人工リンパ組織 / 人工免疫組織 / Antigen presenting cells / 膵腎同時移植 / テロメラーゼ / Artificial antigens / 食道癌 / Cancer / 腫瘍増殖関連遺子 / 悪性腫瘍 / 人工結合組織 / Dissemination / 抗原提示細胞 / T lymphocytes / reconstruction therapy of immune surveillance system / 虚血再潅流障害 / GS 阻害剤 / telomerase / 癌免疫療法 / Biliary tract / 胆道癌 / 高次免疫組織 / IFN-g / Intercellular transmission / 温阻血 / 腫瘍浸潤リンパ球 / early pancreatic cancer / ネオアンチゲン / Breast cancer / Taxane / kidney / cancer-related factors / peritoneal trnasplantation / IFN-_γ / 薬剤耐性 / esophageal cancer / 腫瘍増殖関連遺伝子 / 人工臓器 / 腎臓 / Cancerous ascites / pancreas transplantation / ペプチドがんワクチン療法 / 人工免疫産生装置 / 遺伝子 / スキルス / 乳癌 / invasion / Notch / リンパ球 / Metastasis / 腹膜播種 Less

Development of a new therapeutic strategy regulated Treg cells targeting protein tyrosine phosphatase non-receptor type 3 (PTPN3)Ongoing
- Principal Investigator
  
  永見雅代
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
個別化精密がん免疫療法開発を目的とした腫瘍組織からのネオアンチゲン解析Ongoing
- Principal Investigator
  
  久保真
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
Development of new therapeutical strategy for lung NET by inhibiting Hh/Notch signaling targeting RBPJPrincipal InvestigatorOngoing
- Principal Investigator
  
  森崎隆
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kyushu University
Analysis of the mechanism of augmentation of random migration in lymphocytes and verification of the significance as a biomarker predicting therapeutic effect of immunotherapyPrincipal Investigator
- Principal Investigator
  
  Morisaki Takashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
The development of the system estimating realtime antitumor activity of activated T lymphocytes in cancer immunotherapyPrincipal Investigator
- Principal Investigator
  
  MORISAKI Takashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Suppression of induction and accumulation at tumor site of regulatory T cells by inhibition of VEGF/VEGFR2 pathwayPrincipal Investigator
- Principal Investigator
  
  MORISAKI Takashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Identification and clinical application of colon cancer-specific gamma-secretase-targeting molecules
- Principal Investigator
  
  YAMAGUCHI Kouji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Development of DC-based vaccine therapy by utilizing exosomes collected from healthy volunteer-derived DCsPrincipal Investigator
- Principal Investigator
  
  MORISAKI Takashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Development of the next generation cancer therapy using "Exosomes" by molecular tumor engineering technique
- Principal Investigator
  
  KATANO Mitsuo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  KYUSHU UNIVERSITY
Development of the breast cancer therapy using intercellular transmission by small vesicle (Exosomes) having fusion faculty
- Principal Investigator
  
  KUROKI Shouji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  KYUSHU UNIVERSITY
腫瘍パルス樹状細胞の固相化培養装置を利用した腫瘍特異的リンパ球の培養と臨床応用Principal Investigator
- Principal Investigator
  
  森崎隆
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
生体外修飾を行った「再生免疫組織」による癌特異免疫療法への応用
- Principal Investigator
  
  UCHIYAMA Akihiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Irtercellular molecular transfer of OX40 in novel anti-tumor immunotherapy
- Principal Investigator
  
  BABA Eishi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  KYUSHU UNIVERSITY
Experimental study of FR167653 in simultaneous pancreas and kidney transplantation from non-heart-beating donor
- Principal Investigator
  
  SUGITANI Atushi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Development of artificial 3-dimensional cancer tissue model as tool for pathological analysis and therapeutic research for malignant solid tumor
- Principal Investigator
  
  NOSHIRO Hirokazu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  KYUSHU UNIVERSITY
A higher immune system model by combination of several types of artificial tissues (connective tissue, carcinoma tissue, and lymphoid tissue)
- Principal Investigator
  
  KATANO Mitsuo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Arificial biliary duct model for surgical therapeutic material and research material for biliary cancerPrincipal Investigator
- Principal Investigator
  
  MORISAKI Takashi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
New therapy combined with immunology, molecular biology and medical technology for patients with peritoneal carcinosis
- Principal Investigator
  
  KATANO Mitsuo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  KYUSHU UNIVERSITY
Experimental study of FR167653 on ischemia- reperfusion injury in canine simultaneous pancreas and kidney transplantation from non-heart-beating donor
- Principal Investigator
  
  SUGITANI Atushi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  KYUSHU UNIVERSITY
Artificial Peritoneum for Cancer Research and Surgical Treatment
- Principal Investigator
  
  UCHIYAMA Akihiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  KYUSHU UNIVERSITY
Clinical utilization of profiles of cancer-related factors in gastric and esophageal cancer
- Principal Investigator
  
  NOSHIRO Hirokazu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  KYUSHU UNIVERSITY
Treatment of multiple oragn dysfunction syndrom : establisment of endothelial cell targetting therapyPrincipal Investigator
- Principal Investigator
  
  MORISAKI Takashi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  KYUSHU UNIVERSITY
Molecular diagnosis of pancreatic cancer by telomerase
- Principal Investigator
  
  MIZUMOTO Kazuhiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  KYUSHU UNIVERSITY
New strategy against pancteato-biliary carcinoma using NK4, a four-kringle antagonist of hepatocyte growth factor
- Principal Investigator
  
  TANAKA Masao
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
Establisment of tumor vaccine using autologous dendritic cells and its application for addaptive immunotherapyPrincipal Investigator
- Principal Investigator
  
  MORISAKI Takashi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  KYUSHU UNIVERSITY

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2005 2004 2003 2002 Other

All Journal Article Presentation Book

[Book] Regulatory T cell: Immunotherapy of Cancer: An Innovative Treatment Comes of Age.2016
- Author(s)
  Onishi H, Morisaki T, Katano M
- Total Pages
  358
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-15K10055
[Book] Immunotherapy of Cancer: An Innovative Treatment Comes of Age: Regulatory T Cells2016
- Author(s)
  Hideya Onishi, Takashi Morisaki, Mitsuo Katano.
- Total Pages
  358
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-15K10055
[Journal Article] 患者さんを見据えた全人的癌治療―低酸素環境とHedgehog Signal―2017
- Author(s)
  大西秀哉、荻野利達、森崎　隆、片野光男
- Journal Title
  
  癌と化学療法
  
  Volume: 44 Pages: 977-980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10055
[Journal Article] Stage IV gastric cancer successfully treated multidisciplinary therapy including immunotherapy: a case report2017
- Author(s)
  Kawamoto M, Onishi H, Koya N, Konomi H, Mitsugi K, Tanaka R, Motoshita J, Morisaki T, Nakamura M
- Journal Title
  
  Surgery Case Rep
  
  Volume: 3 Pages: 112-112
- DOI
  10.1186/s40792-017-0380-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05402, KAKENHI-PROJECT-15K10055, KAKENHI-PROJECT-16K15593
[Journal Article] Sugar-carrying Polystyrenes Facilitate Harvesting of APCs from MLRs: Possible Application of Sugar-carrying Polystyrenes to Immunotherapy.2016
- Author(s)
  Imaizumi A, Onishi H, Yamasaki A, Kawamoto M, Morisaki T, Goto M, Iwama M, Akaike T, Hasumi K.
- Journal Title
  
  Anticancer Research
  
  Volume: 36(2) Pages: 673-676
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10055
[Journal Article] Hedgehog signaling regulates PDL-1 expression in cancer cells to induce anti-tumor activity by activated lymphocytes.2016
- Author(s)
  Onishi H, Fujimura A, Oyama Y,Yamasaki A, Imaizumi A, Kawamoto M, Katano M, Umebayashi M, Morisaki T
- Journal Title
  
  Cellular Immunology
  
  Volume: 310 Pages: 199-204
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10055
[Journal Article] NKG2D-directed cytokine-activated killer lymphocyte therapy combined with gemcitabine for patients with chemoresistant metastatic solid tumors.2014
- Author(s)
  Morisaki T, Hirano T, Koya N, Kiyota A, Tanaka H, Umebayashi M, Onishi H, Katano M
- Journal Title
  
  Anticancer Res
  
  Volume: 34(8) Pages: 4529-4538
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591908
[Journal Article] An epithelial cell adhesion molecule- and CD3 bispecific antibody plus activated T-cells can eradicate chemoresistant cancer stem-like pancreatic carcinoma cells in vitro.2014
- Author(s)
  Umebayashi M, Kiyota A, Koya N, Tanaka H, Onishi H, Katano M, Morisaki T
- Journal Title
  
  Anticancer Res
  
  Volume: 34(8) Pages: 4509-4520
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591908
[Journal Article] Random Migration Contributes to Cytotoxicity of Activated CD8+ T-Lymphocytes but not NK cells.2014
- Author(s)
  Onishi H, Kiyota A, Koya N, Tanaka H, Umebayashi M, Katano M, Morisaki T
- Journal Title
  
  Ａｎｔｉｃａｎｃｅｒ　Ｒｅｓ
  
  Volume: 34(8) Pages: 3947-3956
- Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591908
[Journal Article] The Hedgehog inhibitor suppresses the function of monocyte-derived dendritic cells from patients with advanced cancer under hypoxia.2013
- Author(s)
  Onishi H, Morisaki T, Kiyota A, Koya N, Tanaka H, Umebayashi M, Katano M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 436(1) Pages: 53-59
- DOI
  10.1016/j.bbrc.2013.05.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591894, KAKENHI-PROJECT-24390303, KAKENHI-PROJECT-24591908
[Journal Article] The Hedgehog inhibitor cyclopamine impairs the benefits of immunotherapy with activated T and NK lymphocytes derived from patients with advanced cancer2013
- Author(s)
  Onishi H, Morisaki T, Kiyota A, Koya N, Tanaka H, Umebayashi M, Katano M
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: 62（6） Pages: 1029-1039
- DOI
  10.1007/s00262-013-1419-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591894, KAKENHI-PROJECT-24591908
[Journal Article] Combining cetuximab with killer lymphocytes synergistically inhibits human.2012
- Author(s)
  Morisaki T, Onishi H, Katano M et al.
- Journal Title
  
  Anticancer Research
  
  Volume: 32(6) Pages: 2249-2256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591908
[Journal Article] Cancer immunotherapy using NKG2D and DNAM-1 systems.2012
- Author(s)
  Morisaki T, Onishi H, Katano M
- Journal Title
  
  Anticancer Research
  
  Volume: 32(6) Pages: 2241-2247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591908
[Journal Article] Inclusive estimation of complex antigen presentation functions of monocyte-derived dendritic cells differentiated under normoxia and hypoxia conditions.2012
- Author(s)
  Ogino T, Morisaki T, et al
- Journal Title
  
  Cancer Immunol Immnunother
  
  Volume: 61 Pages: 409-424
- DOI
  10.1007/s00262-011-1112-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591670, KAKENHI-PROJECT-23591894
[Journal Article] Inclusive estimation of complex antigen presentation functions of monocytederived dendritic cells differentiated under normoxia and hypoxia conditions2012
- Author(s)
  Ogino T, Onishi H(6人中2番目), Morisaki T(4番目), Katano M(6番目) et al
- Journal Title
  
  Cancer Immunology Immunotherapy
  
  Volume: 61 Pages: 409-424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591670
[Journal Article] Immunotherapy approaches targeting regulatory T-cells2012
- Author(s)
  Onishi H, Morisaki T, Katano M.
- Journal Title
  
  Anticancer Research
  
  Volume: 32 Pages: 997-1003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591670
[Journal Article] A new method for rapid cytotoxic T-lymphocyte induction using a multiple cytokine.2012
- Author(s)
  Onishi H, Katano M, Morisaki T et al.
- Journal Title
  
  Anticancer Research
  
  Volume: 32(6) Pages: 2385-2390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591908
[Journal Article] Combinatorial cytotoxicity of gemcitabine and cytokine-activate killer cells in hepatocellular carcinoma via the NKG2D-MICA/B system2011
- Author(s)
  Morisaki T, et al
- Journal Title
  
  Anticancer Research
  
  Volume: 31 Pages: 2505-2510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591670
[Journal Article] Combinatorial cytotoxicity of gemcitabine and cytokine-activate killer cells in hepatocellular carcinoma via the NKG2DMICA/B system2011
- Author(s)
  Morisaki T(9人中1番目), Onishi H(2番目), Katano M(9番目) et al
- Journal Title
  
  Anticancer Research
  
  Volume: 31 Pages: 2505-2510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591670
[Journal Article] Treg制御による癌免疫療法2010
- Author(s)
  片野光男、大西秀哉、森崎隆、鈴木宏往、荻野利達
- Journal Title
  
  Surgery Frontier
  
  Volume: 17(3) Pages: 61-64
- Data Source
  KAKENHI-PROJECT-21591670
[Journal Article] VEGFR2 is selectively expressed by FOXP3high CD4^+ Treg2010
- Author(s)
  Suzuki H, Onishi H, Wada J, Yamasaki A, Tanaka H, Nakano K, Morisaki T, Katano M.
- Journal Title
  
  European Journal of Immunology
  
  Volume: 40 Pages: 197-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591670
[Journal Article] Treg制御による癌免疫療法2010
- Author(s)
  片野光男、森崎隆, ほか
- Journal Title
  
  Surgical Frontier
  
  Volume: 17 Pages: 259-262
- Data Source
  KAKENHI-PROJECT-21591670
[Journal Article] Vascular endothelial growth factor receptor 2 (VEGFR2) is selectively expressed by FOXP3hiehCD4+ regulatory T cells.2010
- Author(s)
  Suzuki H, Morisaki T, Katano M, et al.
- Journal Title
  
  European Journal of Immunology 40
  
  Pages: 197-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591670
[Journal Article] A protein-bound polysaccharide, PSK, enhances tumor suppression induced by docetaxel in a gastric cancer xenograft model.2009
- Author(s)
  Yamasaki A, Shoda M, Iijima H, Nagai S, Wada J, Suzuki H, Chikazawa N, Tasaka T, Kameda C, Tanaka H, Ikebe M, Jo E, Sato N, Nakamura M, Sekine F, Morisaki T, Katano M
- Journal Title
  
  Anticancer Res 29
  
  Pages: 843-850
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390361
[Journal Article] 制御性T細胞の基礎・臨床2009
- Author(s)
  片野光男, 森崎隆, 他
- Journal Title
  
  Biotherapy 22
  
  Pages: 197-214
- Data Source
  KAKENHI-PROJECT-21591670
[Journal Article] The contribution of vascular endothelial growth factor to the induction of regulatory T cells in malignant effusions2009
- Author(s)
  Wada J, Morisaki T, Katano M, et al.
- Journal Title
  
  Anticancer Research 29
  
  Pages: 881-888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591670
[Journal Article] The contribution of vascular endothelial growth factor to the induction of regulatory T-cells in malignant effusions2009
- Author(s)
  Wada J, Suzuki H, Fuchino R, Yamasaki A, Nagai S, Yanai K, Koga K, Nakamura M, Tanaka M, Morisaki T, Katano M.
- Journal Title
  
  Anticancer Research
  
  Volume: 29 Pages: 881-888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591670
[Journal Article] Effects ofdocetaxelonantigen presentation- related functions of human monocyte-derived dendritic cells.2005
- Author(s)
  Nakashima H, Tasaki A, Kubo M, Kuroki H, Matsumoto K, Tanaka M, Nakamura M, Morisaki T, Katano M.
- Journal Title
  
  Cancer Immunol Pharmacol 55
  
  Pages: 479-487
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591339
[Journal Article] Evaluation of a dysfunctional and short-lived subset of monocyte-derived dendritic cells from cancer patients.2005
- Author(s)
  Onishi H, Morisaki T, Kuroki H, Matsumoto K, Baba E, Kuga H, Tanaka M, Katano M
- Journal Title
  
  Anticancer Res 25
  
  Pages: 3445-3451
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390351
[Journal Article] Paclitaxel probably enhances cytotoxicity of natural killer cells against breast carcinoma cells by increasing perforin production.2005
- Author(s)
  Kubo M, Morisaki T, Tasaki A, Yamanaka N, Nakashima H, Kuroki H, Matsumoto K, Nakamura K, Nakamura M, Katano M.
- Journal Title
  
  Cancer Immunol Immunother 54
  
  Pages: 468-476
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591339
[Journal Article] Combination therapy of tumor cell-pulsed dendritic cells and activated lymphocytes for patients with disseminated carcinomas.2005
- Author(s)
  Katano M, Morisaki T, Koga K, Nakamura M, Onishi H, Matsumoto K, Tasaki A, Nakashima H, Akiyoshi T, Nakamura M
- Journal Title
  
  Anticancer Res 25
  
  Pages: 3771-3776
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390351
[Journal Article] Paclitaxel probably enhances cytotoxicity of natural killer cells against breast carcinoma cells by increasing perforin production.2005
- Author(s)
  Kubo M, Morisaki T, Tasaki A, Yamanaka N, Nakashima H, Kuroki H, Matsumoto K, Nakamura K, Nakamura M, Katano M
- Journal Title
  
  Cancer Immunol Immunother 54
  
  Pages: 468-476
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390351
[Journal Article] Combination therapy of tumor cell-pulsed dendritic cells and activated lymphocytes for patients with disseminated carcinomas.2005
- Author(s)
  Katano M, Morisaki T, Koga K, Nakamura M, Onishi H, Matsumoto K, Tasaki A, Nakashima H, Akiyoshi T, Nakamura M.
- Journal Title
  
  Anticancer Res 25
  
  Pages: 3771-3776
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591339
[Journal Article] Evaluation of a dysfunctional and short-lived subset of monocyte-derived dendritic cells from cancer patients.2005
- Author(s)
  Onishi H, Morisaki T, Kuroki H, Matsumoto K, Baba E, Kuga H, Tanaka M, Katano M.
- Journal Title
  
  Anticancer Res 25
  
  Pages: 3445-3451
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591339
[Journal Article] Monocyte-derived dendritic cells that capture dead tumor cells secrete IL-12 and TNF-alpha through IL-12/ TNF-alpha/ NF-kappaB autocrine loop.2004
- Author(s)
  Onishi H, Kuroki H, Matsumoto K, Haba.E, Sasaki N, Kuga H, Tanaka M, Katano M, Morisaki T.
- Journal Title
  
  Cancer Immunol Immunother 53
  
  Pages: 1093-1100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570417
[Journal Article] Three-dimensional two-layer collagen matrix gel culture model for evaluating complex biological functions of monocyte-derived dendritic cells.2004
- Author(s)
  Tasaki A, Yamanaka N, Kubo M, Matsumoto K, Kuroki H, Nakamura K, Nakahara C, Onishi H, Kuga H, Baba E, Tanaka M, Morisaki T, Katano M.
- Journal Title
  
  J Immunol Methods 287(1-2)
  
  Pages: 79-90
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570417
[Journal Article] Combined immunotherapy with intracavital injection of activated lymphocytes, monocyte-derived dendritic cells and low-dose2003
- Author(s)
  Morisaki T et al.
- Journal Title
  
  Anticancer Research 23
  
  Pages: 4459-4465
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570417
[Journal Article] Combination of adoptive immunotherapy with Herceptin for patients with HER2-expressing breast cancer.2003
- Author(s)
  Kubo M, Morisaki T, Kuroki H, Tasaki A, Yamanaka N, Matsumoto K, Nakamura K, Onishi H, BabaE, Katano M.
- Journal Title
  
  Anticancer Res. 23(6a)
  
  Pages: 4443-4449
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570417
[Journal Article] Cyclosporin-A enhances docetaxel-induced apoptosis through inhibition of nuclear factor-kB activation in human gastric carcinoma cells.2003
- Author(s)
  Nakahara C, Nakamura K, Yamanaka N, Haba E, Wada M, Matsunaga H, Noshiro H, Tanaka M, Morisaki T, Katano M.
- Journal Title
  
  Clin Cancer Res. 9(14)
  
  Pages: 5409-5416
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570417
[Journal Article] Combined immunotherapy with intracavital injection. of activated lymphocytes, monocyte-derived dendritic cells and low-dose OK-432 in patients with malignant effusion.2003
- Author(s)
  Morisaki T, Matsumoto K, Kuroki H, Kubo M, Baba E, Onishi H, Tasaki A, Nakamura M, Inaba S, Katano M.
- Journal Title
  
  Anticancer Res. 23(6a)
  
  Pages: 4459-4465
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570417
[Journal Article] Dendritic cell-based combined immunotherapy with autologous tumor-pulsed dendritic cell vaccine and activated T cells for cancer patients : rationale, current progress, and perspectives2003
- Author(s)
  Morisaki T et al.
- Journal Title
  
  Human Cell 16
  
  Pages: 175-182
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570417
[Journal Article] Dendritic cell-based combined immunotherapy with autologous tumor-pulsed dendritic cell vaccine and activated T cells for cancer patients : rationale, current progress, and perspectives. Review.2003
- Author(s)
  Morisaki T, Matsumoto K, Onishi H, Kuroki H, BabaE, Tasaki A, Kubo M, Nakamura M, Inaba S, Yamaguchi K, Tanaka M, Katano M.
- Journal Title
  
  Hum Cell 16(4)
  
  Pages: 175-182
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570417
[Journal Article] Streptococal preparation OX-432 : a new maturation factor of monocyte-derived dendritic cells for clinical use.2003
- Author(s)
  Kuroki H, Morisaki T, Matsumoto K, Onishi H, Baba F, Tanaka M, Katano M.
- Journal Title
  
  Cancer Immunol Immunother 52
  
  Pages: 561-568
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570417
[Journal Article] Dysfunctional and short-lived subsets in monocyte-derived dendritic cells from patients with advanced cancer2002
- Author(s)
  Hideya Onishi, Takashi Morisaki, Eishi Baba, Hirotaka Kuga, Hideo Kuroki, Kotaro Matsumoto, Masao Tanaka, Mitsuo Katano
- Journal Title
  
  Clin Immunol 105
  
  Pages: 286-295
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570417
[Journal Article] Regulatory T cells are possible effect prediction markers of immunotherapy for cancer patients
- Author(s)
  Wada, J, Yamasaki, A, Morisaki, T, Nagai, S, Yanai, K, Fuchino, K, Akiyoshi, T, Koga, K, Nakashima, H, Nakamura, M, Tanaka, M, Katano, M
- Journal Title
  
  Anticancer Research (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591440
[Presentation] 活性化リンパ球のrandom migration能は癌免疫療法の効果予測因子となりうる2017
- Author(s)
  川元　真　大西秀哉　山崎章生　森崎　隆　村橋睦了　緒方久修　中村雅史
- Organizer
  第２３回　国際個別化医療学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10055
[Presentation] 抗PD-1抗体が著効した切除不能上顎洞癌の一例2017
- Author(s)
  藤村晶子、古後龍之介、森崎　隆、中川尚志、大西秀哉
- Organizer
  第３０回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-15K10055
[Presentation] 癌特異的な免疫監視機構の構築により良好な経過を得ているstage IV胃癌の１例2017
- Author(s)
  川元　真、森崎　隆、大西秀哉
- Organizer
  第７２回　日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-15K10055
[Presentation] 抗PD-1抗体が著効した切除不能上顎洞癌の１例2017
- Author(s)
  山崎章生、大西秀哉、藤村晶子、川元真、森崎隆
- Organizer
  第２１回バイオ治療法研究会学術集会
- Data Source
  KAKENHI-PROJECT-15K10055
[Presentation] 免疫細胞療法と抗PD-1抗体でCRとなった耳下腺癌多発転移の一例2016
- Author(s)
  藤村　晶子、大西　秀哉、益田　宗幸、中川　尚志、森崎　隆
- Organizer
  第２９回　日本バイオセラピィ学会学術集会総会
- Place of Presentation
  久留米シティプラザ（福岡県・久留米市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K10055
[Presentation] 活性化リンパ球における Hedgehog signal の生物学的意義の解析2016
- Author(s)
  大西　秀哉、森崎　隆、山崎　章生、川元　真、中村　雅史
- Organizer
  第３７回　癌免疫外科研究会
- Place of Presentation
  川越プリンスホテル（埼玉県・川越市）
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-15K10055
[Presentation] 低酸素環境下、活性化リンパ球および樹状細胞におけるHedgehogシグナルの生物学的役割の解析2016
- Author(s)
  大西　秀哉、藤村　晶子、大山　康博、川元　真、山崎　章生、今泉　晃、中村　雅史、森崎　隆
- Organizer
  第２９回　日本バイオセラピィ学会学術集会総会
- Place of Presentation
  久留米シティプラザ（福岡県・久留米市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K10055
[Presentation] 活性化リンパ球のランダムマイグレーションは癌免疫療法の効果増強の指標となり得るか2015
- Author(s)
  大西秀哉、森崎隆、山崎章生、川元真、片野光男、中村雅史
- Organizer
  第２８回日本バイオセラピィ学会学術集会総会
- Place of Presentation
  川越東武ホテル（埼玉県・川越市）
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-15K10055
[Presentation] 活性化リンパ球のランダムマイグレーションと細胞傷害活性は関与するか2015
- Author(s)
  大西秀哉、森崎隆、山崎章生、川元真、永井英司、大内田研宙、真鍋達也、植木隆、宮坂義浩、大塚隆生、中村雅史
- Organizer
  第７７回日本臨床外科学会総会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-15K10055
[Presentation] 癌免疫細胞療法の治療効果予測バイオマーカーの探索：ランダムマイグレーション2015
- Author(s)
  大西秀哉、森崎隆、山崎章生、大内田研宙、永井英司、片野光男、中村雅史
- Organizer
  第５３回日本癌治療学会学術集会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2015-10-29
- Data Source
  KAKENHI-PROJECT-15K10055
[Presentation] 個別化免疫細胞療法確立への試み2014
- Author(s)
  大西　秀哉、森崎　隆、梅林　雅代、古屋　雄大、田中　裕人、清田　章文、片野　光男
- Organizer
  第35回癌免疫外科研究会
- Place of Presentation
  シェラトン都ホテル大阪（大阪府・大阪市）
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-24591908
[Presentation] Hedgehogシグナル阻害剤は活性化リンパ球療法の効果を減弱する2013
- Author(s)
  大西　秀哉、森崎　隆、清田　章文、梅林　雅代、古屋　雄大、田中　裕人、片野　光男
- Organizer
  第26回日本バイオセラピィ学会
- Place of Presentation
  いわて県民情報交流センターアイーナ（盛岡市）
- Data Source
  KAKENHI-PROJECT-24591908
[Presentation] 制御性T細胞を標的としたテーラーメード消化器癌免疫療法2013
- Author(s)
  大西　秀哉、森崎　隆、片野　光男
- Organizer
  第68回日本消化器外科学会総会
- Place of Presentation
  サンホテルフェニックス（宮崎市）
- Data Source
  KAKENHI-PROJECT-24591908
[Presentation] 免疫細胞療法テーラーメード化確立への試み2013
- Author(s)
  大西　秀哉、森崎　隆、梅林　雅代、古屋　雄大、田中　裕人、清田　章文、片野　光男
- Organizer
  第38回日本外科系連合学会
- Place of Presentation
  ハイアットリージェンシー東京（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-24591908
[Presentation] 個別化（テ－ラーメード）癌免疫細胞療法と地域医療
- Author(s)
  森崎　隆
- Organizer
  第５回　福岡県医学会総会
- Place of Presentation
  福岡県医師会館（福岡市）
- Data Source
  KAKENHI-PROJECT-24591908
[Presentation] ジェムザール併用活性化リンパ球の臨床効果とそのメカニズムの検討
- Author(s)
  森崎　隆、清田　章文、田中　裕人、梅林　雅代、古屋　雄大、大西　秀哉、片野　光男
- Organizer
  第１７回バイオ治療法研究会
- Place of Presentation
  福岡大学病院・福大メディカルセンター（福岡市）
- Data Source
  KAKENHI-PROJECT-24591908

1. KATANO Mitsuo (10145203)

# of Collaborated Projects: 16 results

# of Collaborated Products: 37 results
2. UCHIYAMA Akihiko (20294936)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
3. ONISHI Hideya (30553276)

# of Collaborated Projects: 7 results

# of Collaborated Products: 35 results
4. MATSUDA Takehisa (60142189)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
5. SUEISHI Katsuo (70108710)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. KUBO Makoto (60403961)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
7. TANAKA Masao (30163570)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
8. BABA Eishi (00315475)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
9. NAKAMURA Masafumi (30372741)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
10. KOJIMA Masayuki (90380394)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. IMAIZUMI Akira (30624051)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
12. MIZUMOTO Kazuhiro (90253418)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
13. YAMAMOTO Hirofumi

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
14. YAMAGUCHI Kouji (50191226)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. DOI Fukashi (10315062)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. SUGITANI Atushi (00294934)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. NOSHIRO Hirokazu (90301340)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. 桟敷俊信 (20315089)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. 三好圭 (70755272)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. 永井俊太郎 (90755240)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. KITADA Hidehisa

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
22. SATOH Norihiro (20423527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. NAKAMURA Katsuya (60585743)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. NAKAMURA Toshikazu (00049397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SHIMURA Hideo (80178996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. ARIMA Takeshi (60315083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. TANAKA Yuetsu (30163588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
28. NOMURA Masatoshi (30315080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. TANI Kenzaburou (00183864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KUROKI Shouji (30215090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
31. 小川尚洋 (90294933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 山崎章生 (80404440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
33. 甲斐昌也 (10755242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 大内田研宙 (20452708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 永見雅代 (80792209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. KINOSHITA Moritoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 井上重隆

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. KENJI Nakano

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Morisaki Takashi 森崎 隆

MORISAKI Takashi 森崎 隆

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Co-Researchers

Development of a new therapeutic strategy regulated Treg cells targeting protein tyrosine phosphatase non-receptor type 3 (PTPN3)Ongoing

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個別化精密がん免疫療法開発を目的とした腫瘍組織からのネオアンチゲン解析Ongoing

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Development of new therapeutical strategy for lung NET by inhibiting Hh/Notch signaling targeting RBPJPrincipal InvestigatorOngoing

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Analysis of the mechanism of augmentation of random migration in lymphocytes and verification of the significance as a biomarker predicting therapeutic effect of immunotherapyPrincipal Investigator

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The development of the system estimating realtime antitumor activity of activated T lymphocytes in cancer immunotherapyPrincipal Investigator

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Suppression of induction and accumulation at tumor site of regulatory T cells by inhibition of VEGF/VEGFR2 pathwayPrincipal Investigator

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Development of DC-based vaccine therapy by utilizing exosomes collected from healthy volunteer-derived DCsPrincipal Investigator

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腫瘍パルス樹状細胞の固相化培養装置を利用した腫瘍特異的リンパ球の培養と臨床応用Principal Investigator

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Morisaki Takashi 森崎隆

MORISAKI Takashi 森崎隆