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Gomi Hiroshi  五味 浩司

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五味 浩司  ゴミ ヒロシ

GOMI Hiroshi  五味 浩司

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Researcher Number 90293240
Other IDs
Affiliation (Current) 2021: 日本大学, 生物資源科学部, 教授
Affiliation (based on the past Project Information) *help 2020: 日本大学, 生物資源科学部, 教授
2013 – 2018: 日本大学, 生物資源科学部, 教授
2011 – 2012: 日本大学, 生物資源科学部, 准教授
2010: 群馬大学, 生体調節研究所, 准教授
2007 – 2008: Gunma University, 生体調節研究所, 准教授
2001 – 2006: 群馬大学, 生体調節研究所, 助教授
1998 – 1999: 理化学研究所, 行動遺伝学技術開発チーム, 研究員
Review Section/Research Field
Principal Investigator
Neuroscience in general / Integrative animal science / Experimental pathology / Fusional basic brain science / Basic Section 42020:Veterinary medical science-related
Except Principal Investigator
Biological Sciences / Metabolomics / General physiology
Keywords
Principal Investigator
セクレトグラニン / アストログリア / フォグリン / 分泌顆粒 / ペプチドホルモン / Cdkl2 / KKIAMRE / 瞬目条件反射 / 小脳運動学習 / セリン・スレオニンキナーゼ … More / 遺伝子発現 / 染色体マッピング / 大脳聴覚野 / 一酸化窒素 / 長期増強 / 一酸化窒素合成酵素 / シナプス可塑性 / Alexander病 / グリア線維性酸性タンパク質 / 反応性グリオーシス / GFAP / 病態モデルマウス / ニューロングリア相互作用 / グリオトランスミッター / トリパータイトシナプス / アストロサイト / トランスジェニックマウス / 細胞内カルシウム / グリオトランスミックー / IA-2ファミリータンパク質 / 消化管内分泌細胞 / 膵β細胞 / 膵島 / IA-2ファミリー蛋白質 / セリン-スレオニンキナーゼ / ジーンターゲッティング / ノックアウトマウス / 発生 / 遺伝子発現解析 / 脳高次機能 / 瞬目反射学習 / 小脳深部核 / serine-threonine kinase / gene targeting / knock-out mice / ontogeny / gene expression / brain function / 内分泌細胞 / トランスゴルジネットワーク / リソソーム / 遺伝子欠損マウス / 活性アミン産生細胞 / SNAREタンパク質 / IA2ファミリータンパク質 / グラニンタンパク質 / 細胞・組織 / 応用動物 / 生理活性 / 遺伝子 / 解剖学 / 副腎髄質 / ジーントラップマウス / 神経内分泌疾患 … More
Except Principal Investigator
インスリン / 分泌顆粒 / 糖尿病 / 肥満 / 量的形質遺伝子座 / モデル動物 / コンジェニックマウス / 調節性分泌 / 蛍光蛋白質 / 遺伝子変異マウス / Insulin / Secretory granules / Regulated exocytosis / Fluorescent protein / Mutated mouse / ペプチドホルモン / オートクライン / チロシンホスファターゼ / 膵島 / 細胞内輸送 / 細胞内分解 Less
  • Research Projects

    (10 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (11 People)
  •  セクレトグラニンⅢの機能的多様性と疾患関連性の解析Principal InvestigatorOngoing

    • Principal Investigator
      五味 浩司
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Nihon University
  •  Elucidation of formation and degradation mechanism of peptide hormone-containing secretory granules (the life of secretory granules)Principal Investigator

    • Principal Investigator
      GOMI Hiroshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Integrative animal science
    • Research Institution
      Nihon University
  •  The role of IA-2 family proteins in the endocrine cells of gastrointestinal tractPrincipal Investigator

    • Principal Investigator
      GOMI Hiroshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Integrative animal science
    • Research Institution
      Nihon University
  •  Stabilizing endocrine cell function by phogrin.

    • Principal Investigator
      TORII SEIJI
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Gunma University
  •  Functional analysis of gliotransmittersPrincipal Investigator

    • Principal Investigator
      GOMI Hiroshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Fusional basic brain science
    • Research Institution
      Nihon University
      Gunma University
  •  Generation and analysis of mice model for Alexander diseasePrincipal Investigator

    • Principal Investigator
      GOMI Hiroshi
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Gunma University
  •  Visualization of insulin granules in pancreatic beta cells derived from genetically altered mouse models.

    • Principal Investigator
      IZUMI Testuro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Gunma University
  •  多因子遺伝性糖尿病・肥満モデルマウスの成因遺伝子の解明

    • Principal Investigator
      IZUMI Testuro
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  Functional Roles and Transcriptional Regulation of Cdkl2/KKIAMRE in Mouse BrainPrincipal Investigator

    • Principal Investigator
      GOMI Hiroshi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neuroscience in general
    • Research Institution
      Gunma University
  •  脳の聴覚情報処理機構におけるアストログリアの役割Principal Investigator

    • Principal Investigator
      五味 浩司
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Neuroscience in general
    • Research Institution
      The Institute of Physical and Chemical Research

All 2019 2018 2017 2016 2015 2013 2012 2010 2008 2007 2006 2005 Other

All Journal Article Presentation

  • [Journal Article] Culture in 10% O2 enhances the production of active hormones in neuro-endocrine cells by up-regulating the expression of processing enzyme.2019

    • Author(s)
      Sato E, Maeda Y, Sato Y, Hinata A, Gomi H, Koga D, Torii S, Watanabe T, Hosaka M
    • Journal Title

      Biochemical Journal

      Volume: 476 Pages: 827-842

    • DOI

      10.1042/bcj20180832

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08458, KAKENHI-PROJECT-17K08528, KAKENHI-PROJECT-16K08078, KAKENHI-PROJECT-18K05443, KAKENHI-PROJECT-17K08505
  • [Journal Article] Impaired processing of prohormones in secretogranin III-null mice causes maladaptation to an inadequate diet and stress.2018

    • Author(s)
      Maeda Y, Kudo S, Tsushima K, Sato E, Kubota C, Kayamori A, Bochimoto H, Koga D, Torii S, Gomi H, Watanabe T, Hosaka M
    • Journal Title

      Endocrinology

      Volume: 159 Pages: 1213-1227

    • DOI

      10.1210/en.2017-00636

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08505, KAKENHI-PROJECT-17K08528, KAKENHI-PROJECT-15K18951, KAKENHI-PROJECT-17J40226, KAKENHI-PROJECT-16K08458, KAKENHI-PROJECT-16K08078
  • [Journal Article] The pseudophosphatase phogrin enables glucose-stimulated insulin signaling in pancreatic β cells.2018

    • Author(s)
      Torii Seiji、Kubota Chisato、Saito Naoya、Kawano Ayumi、Hou Ni、Kobayashi Masaki、Torii Ryoko、Hosaka Masahiro、Kitamura Tadahiro、Takeuchi Toshiyuki、Gomi Hiroshi
    • Journal Title

      Journal of Biological Chemistry

      Volume: 293 Pages: 5920-5933

    • DOI

      10.1074/jbc.ra117.000301

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08528, KAKENHI-PROJECT-17J40226, KAKENHI-PROJECT-16K08078
  • [Journal Article] Ultrastructure and immunohistochemical characterization of proteins concerned with the secretory machinery in goat ceruminous glands.2017

    • Author(s)
      Tadashi Yasui, Hiroshi Gomi, Taishi Kitahara, Azuma Tsukise
    • Journal Title

      European Journal of Histochemistry

      Volume: 61 Pages: 222-230

    • DOI

      10.4081/ejh.2017.2828

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08078
  • [Journal Article] Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.2017

    • Author(s)
      Hiroshi Gomi, Hiromi Osawa, Rie Uno, Tadashi Yasui, Masahiro Hosaka, Seiji Torii, Azuma Tsukise
    • Journal Title

      J Histochem Cytochem

      Volume: 65 Pages: 637-653

    • DOI

      10.1369/0022155417732527

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08078, KAKENHI-PROJECT-17K08528
  • [Journal Article] Expression of secretogranin III in chicken endocrine cells: its relevance to the secretory granule properties of peptide prohormone processing and bioactive amine content.2015

    • Author(s)
      Gomi H, Morikawa S, Shinmura N, Moki H, Yasui T, Tsukise A, Torii S, Watanabe T, Maeda Y, Hosaka M
    • Journal Title

      J. Histochem. Cytochem.

      Volume: 印刷中 Pages: 350-366

    • DOI

      10.1369/0022155415575032

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390050, KAKENHI-PROJECT-25440052, KAKENHI-PROJECT-25450471
  • [Journal Article] Involvement of cyclin-dependent kinase-like 2 in cognitive function required for contextual and spatial learning in mice2013

    • Author(s)
      Hiroshi Gomi, Takayuki Sassa, Richard F. Thompson, Shigeyoshi Itohara
    • Journal Title

      Frontiers in Behavioral Neuroscience

      Volume: vol.4 Pages: 1-14

    • URL

      http://www.frontiersin.org/Behavioral_Neuroscience/10.3389/fnbeh.2010.00017/full

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500367
  • [Journal Article] Immunohistochemical analysis of IA-2 family of protein tyrosine phosphatases in rat gastrointestinal endocrine cells2013

    • Author(s)
      Hiroshi Gomi, Chisato Kubota-Murata, Tadashi Yasui, Azuma Tsukise, Seiji Torii
    • Journal Title

      Journal of Histochemistry & Cytochemistry

      Volume: vol.61 Pages: 156-168

    • URL

      http://jhc.sagepub.com/content/61/2/156.long

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500367
  • [Journal Article] Immunohistochemical analysis of I A-2 family of protein tyrosine phosphatases in rat gastrointestinal endocrine cells.2013

    • Author(s)
      Gomi H
    • Journal Title

      Journal of Histochemistry and Cytochemistry

      Volume: 61 Pages: 156-168

    • DOI

      10.1369/0022155412466872

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689007, KAKENHI-PROJECT-22500367, KAKENHI-PROJECT-24390050, KAKENHI-PROJECT-25450471
  • [Journal Article] Alexey Semyanov, Shigeyoshi Itohara, Astrocyte Ca^<2+> signals are required for the functional integrity oftripartite synapses2013

    • Author(s)
      Mika Tanaka, Pei-Yu Shih, Hiroshi Gomi, Takamasa Yoshida, Junichi Nakai, Reiko Ando, Teiichi Furuichi, Katsuhiko Mikoshiba
    • Journal Title

      Molecular Brain

      Volume: vol.6 Pages: 1-13

    • URL

      http://www.molecularbrain.com/content/6/1/6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500367
  • [Journal Article] Histochemical distribution of sialic acids and antimicrobial substances in porcine carpal glands2012

    • Author(s)
      Hiroshi Gomi
    • Journal Title

      Arch Dermatol Res

      Volume: 304(Online first)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500367
  • [Journal Article] Involvement of cyclin-dependent kinase-like 2 in cognitive function required for contextual and spatial learning in mice2010

    • Author(s)
      Hiroshi Gomi
    • Journal Title

      Frontiers in Behavioral Neuroscience

      Volume: VOL.4 Pages: 1-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500367
  • [Journal Article] Docking is not a prerequisite but a temporal constraint for fusion of secretory granules2008

    • Author(s)
      Kasai K, Fujita T, Gomi H, Izumi T
    • Journal Title

      Traffic 9

      Pages: 1191-1203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390109
  • [Journal Article] Secretory vesicle docking to the plasma Inembrane:molecUIar mechani2007

    • Author(s)
      Izumi, T., Kasai, K., Gomi, H.
    • Journal Title

      Diabetes Obesity Metabolism 9(spl.2)

      Pages: 109-117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390109
  • [Journal Article] Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane2007

    • Author(s)
      Gomi H, Mori K, Itohara S, Izumi T
    • Journal Title

      Molecular Biology of the Cell 18(11)

      Pages: 4377-4386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390109
  • [Journal Article] Exophilin4/Slp2-a targets glucagon granUles to the plasma membrane through unique Ca^2+-inhibitory phospholipid-binding activity of the C2Adomain2007

    • Author(s)
      Yu, M., Kasai, K., Nagashima, K., Torh, S., Yokota-Hashimoto, H., Okamoto, K., Takeuchi, T., Gomi, H., Izumi, T.
    • Journal Title

      Molecular Biology of the Cell 18

      Pages: 688-696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390109
  • [Journal Article] Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane2007

    • Author(s)
      Gomi, H., Mori, K., Itohara, S., Izumi, T.
    • Journal Title

      Molecular Biology of the Cell 18

      Pages: 4377-4386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390109
  • [Journal Article] Secretory vesicle docking to the plasma membrane : molecular mechanism and functional significance2007

    • Author(s)
      Izumi T, Kasai K, Gomi H
    • Journal Title

      Diabetes Obesity and Metabolism 9(2)

      Pages: 109-117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390109
  • [Journal Article] Enhanced hippocampal neurodegeneration after traumatic or kinate excitotoxicity in GFAP-null mice2006

    • Author(s)
      Otani N, Nawashiro H, Fukui S, Shima K, Gomi H, Brenner M
    • Journal Title

      Journal of Clinical Neuroscience 13(9)

      Pages: 934-938

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390109
  • [Journal Article] Enhanced hippocampal neurodegeneration after traumatic or kinate excitotoxicity in GFAP-null mice2006

    • Author(s)
      Otani, N., Nawashiro, H., Fukui, S., Shima K., Gomi, H., Brenner,M.
    • Journal Title

      Journal of Clinical Neuroscience 13 (9)

      Pages: 934-938

    • Data Source
      KAKENHI-PROJECT-17390109
  • [Journal Article] Chromosome 2 locus Nidd5 has a potent effect on adiposity in the TSOD mouse2006

    • Author(s)
      Mizutani S, Gomi H, Hirayama I, Izumi T
    • Journal Title

      Mammalian Genome 17(5)

      Pages: 375-384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390109
  • [Journal Article] Functional analysis of Rab27a effector granuphilin in insulin secretion2005

    • Author(s)
      Izumi T, Gomi H, Torii S
    • Journal Title

      Methods in Enzymology : GTPases Regulating Menmbrane Targeting and Fusion 403(18)

      Pages: 216-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390109
  • [Journal Article] Granuphilin molecularly docks insulin granules to the fusion machinery.2005

    • Author(s)
      Gomi H., et al.
    • Journal Title

      J. Cell. Biol. 171

      Pages: 99-109

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390261
  • [Journal Article] Granuphilin molecularly docks insulin granules to the fusion machinery2005

    • Author(s)
      Gomi H, Mizutani S, Kasai K, Itohara S, Izumi T
    • Journal Title

      Journal of Cell Biology 171(1)

      Pages: 99-109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390109
  • [Journal Article] Granuphilin molecularly docks insulin granules to the fusion machinery.2005

    • Author(s)
      Gomi H., et al.
    • Journal Title

      J.Cell.Biol. 171

      Pages: 99-109

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390261
  • [Presentation] 分泌顆粒蛋白質フォグリンによるインスリン分泌とシグナルの連結機構2018

    • Author(s)
      久保田知里、齊藤直也、河野あゆみ、竹内利行、小林雅樹、北村忠弘、穂坂正博、五味浩司、鳥居征司
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16K08078
  • [Presentation] イヌ口腔腺におけるRabおよびSNAREタンパク質の発現解析2018

    • Author(s)
      五味浩司、大澤裕美、宇野理恵、安井禎、鳥居征司、穂坂正博、月瀬東
    • Organizer
      第161回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K08078
  • [Presentation] イヌ涙腺における糖質ならびに免疫組織化学的解析2018

    • Author(s)
      安井禎、五味浩司
    • Organizer
      第161回日本獣医学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K08078
  • [Presentation] ニワトリ内分泌器官におけるセクレトグラニンIIIの発現 解析2016

    • Author(s)
      五味 浩司、安井 禎、鳥居 征司、穂坂 正博
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      日本大学生物資源科学部(神奈川県藤沢市)
    • Year and Date
      2016-09-06
    • Data Source
      KAKENHI-PROJECT-16K08078
  • [Presentation] シバヤギ耳道腺における抗菌物質と分泌制御タンパク質の 免疫組織化学的解析2016

    • Author(s)
      安井 禎、五味 浩司
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      日本大学生物資源科学部(神奈川県藤沢市)
    • Year and Date
      2016-09-06
    • Data Source
      KAKENHI-PROJECT-16K08078
  • [Presentation] Exophilin4/Slp2-a targetsglucagon granules to the plasma membrane throughunique Ca2^+-inhibitory phospholipid-binding activity of the C2A domain2007

    • Author(s)
      Kasai, K., YU, M., Gomi, H., Izumi, T.
    • Organizer
      第40回日本発生生物学会・第59回日本細胞生物学会合同大会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-17390109
  • [Presentation] ラット腸管内分泌細胞におけるIA2チロシンホスファターゼ分子群の発現様式(Immunohistochemical analysis of IA2 family of protein-tyrosine phosphatases in rat gastrointestinal endocrine cells)

    • Author(s)
      Hiroshi Gomi, Chisato Kubota-Murata, Seiji Torii
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25450471
  • 1.  TORII Seiji (40312904)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 14 results
  • 2.  IZUMI Testuro (00212952)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  ITOHARA Shigeyoshi (60252524)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  NAMEKI Nobukazu (80302959)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MOGAMI Hideo (90311604)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  水谷 伸 (20323371)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  安井 禎 (70434107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 8.  HOSAKA Masahiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 9.  BOCHIMOTO Hiroki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  KOGA Daisuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 11.  渡部 剛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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