Gomi Hiroshi 五味浩司

… Alternative Names

Researcher Number	90293240
Other IDs
Affiliation (Current)	2020: 日本大学, 生物資源科学部, 教授
Affiliation (based on the past Project Information) *help	2020: 日本大学, 生物資源科学部, 教授 2013 – 2018: 日本大学, 生物資源科学部, 教授 2011 – 2012: 日本大学, 生物資源科学部, 准教授 2010: 群馬大学, 生体調節研究所, 准教授 2007 – 2008: Gunma University, 生体調節研究所, 准教授 2001 – 2006: 群馬大学, 生体調節研究所, 助教授 1998 – 1999: 理化学研究所, 行動遺伝学技術開発チーム, 研究員
Review Section/Research Field	Principal Investigator Neuroscience in general / Integrative animal science / Experimental pathology / Fusional basic brain science / Basic Section 42020:Veterinary medical science-related Except Principal Investigator Biological Sciences / Metabolomics / General physiology
Keywords	Principal Investigator セクレトグラニン / アストログリア / フォグリン / 分泌顆粒 / ペプチドホルモン / Cdkl2 / KKIAMRE / 瞬目条件反射 / 小脳運動学習 / セリン・スレオニンキナーゼ … More Except Principal Investigator インスリン / 分泌顆粒 / 糖尿病 / 肥満 / 量的形質遺伝子座 / モデル動物 / コンジェニックマウス / 調節性分泌 / 蛍光蛋白質 / 遺伝子変異マウス / Insulin / Secretory granules / Regulated exocytosis / Fluorescent protein / Mutated mouse / ペプチドホルモン / オートクライン / チロシンホスファターゼ / 膵島 / 細胞内輸送 / 細胞内分解 Less

セクレトグラニンⅢの機能的多様性と疾患関連性の解析Principal InvestigatorOngoing
- Principal Investigator
  
  五味浩司
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Nihon University
Elucidation of formation and degradation mechanism of peptide hormone-containing secretory granules (the life of secretory granules)Principal Investigator
- Principal Investigator
  
  GOMI Hiroshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  Nihon University
The role of IA-2 family proteins in the endocrine cells of gastrointestinal tractPrincipal Investigator
- Principal Investigator
  
  GOMI Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  Nihon University
Stabilizing endocrine cell function by phogrin.
- Principal Investigator
  
  TORII SEIJI
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Gunma University
Functional analysis of gliotransmittersPrincipal Investigator
- Principal Investigator
  
  GOMI Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Fusional basic brain science
- Research Institution
  Nihon University
  Gunma University
Generation and analysis of mice model for Alexander diseasePrincipal Investigator
- Principal Investigator
  
  GOMI Hiroshi
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Gunma University
Visualization of insulin granules in pancreatic beta cells derived from genetically altered mouse models.
- Principal Investigator
  
  IZUMI Testuro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
多因子遺伝性糖尿病・肥満モデルマウスの成因遺伝子の解明
- Principal Investigator
  
  IZUMI Testuro
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
Functional Roles and Transcriptional Regulation of Cdkl2/KKIAMRE in Mouse BrainPrincipal Investigator
- Principal Investigator
  
  GOMI Hiroshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Gunma University
脳の聴覚情報処理機構におけるアストログリアの役割Principal Investigator
- Principal Investigator
  
  五味浩司
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neuroscience in general
- Research Institution
  The Institute of Physical and Chemical Research

All 2019 2018 2017 2016 2015 2013 2012 2010 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Culture in 10% O2 enhances the production of active hormones in neuro-endocrine cells by up-regulating the expression of processing enzymes.2019
- Author(s)
  Sato E, Maeda Y, Sato Y, Hinata A, Gomi H, Koga D, Torii S, Watanabe T, Hosaka M
- Journal Title
  
  Biochemical Journal
  
  Volume: 476 Pages: 827-842
- DOI
  10.1042/bcj20180832
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08458, KAKENHI-PROJECT-17K08528, KAKENHI-PROJECT-18K05443, KAKENHI-PROJECT-16K08078
[Journal Article] Impaired processing of prohormones in secretogranin III-null mice causes maladaptation to an inadequate diet and stress.2018
- Author(s)
  Maeda Y, Kudo S, Tsushima K, Sato E, Kubota C, Kayamori A, Bochimoto H, Koga D, Torii S, Gomi H, Watanabe T, Hosaka M
- Journal Title
  
  Endocrinology
  
  Volume: 159 Pages: 1213-1227
- DOI
  10.1210/en.2017-00636
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08505, KAKENHI-PROJECT-17K08528, KAKENHI-PROJECT-15K18951, KAKENHI-PROJECT-17J40226, KAKENHI-PROJECT-16K08458, KAKENHI-PROJECT-16K08078
[Journal Article] The pseudophosphatase phogrin enables glucose-stimulated insulin signaling in pancreatic β cells.2018
- Author(s)
  Torii Seiji、Kubota Chisato、Saito Naoya、Kawano Ayumi、Hou Ni、Kobayashi Masaki、Torii Ryoko、Hosaka Masahiro、Kitamura Tadahiro、Takeuchi Toshiyuki、Gomi Hiroshi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 293 Pages: 5920-5933
- DOI
  10.1074/jbc.ra117.000301
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08528, KAKENHI-PROJECT-17J40226, KAKENHI-PROJECT-16K08078
[Journal Article] Ultrastructure and immunohistochemical characterization of proteins concerned with the secretory machinery in goat ceruminous glands.2017
- Author(s)
  Tadashi Yasui, Hiroshi Gomi, Taishi Kitahara, Azuma Tsukise
- Journal Title
  
  European Journal of Histochemistry
  
  Volume: 61 Pages: 222-230
- DOI
  10.4081/ejh.2017.2828
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08078
[Journal Article] Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.2017
- Author(s)
  Hiroshi Gomi, Hiromi Osawa, Rie Uno, Tadashi Yasui, Masahiro Hosaka, Seiji Torii, Azuma Tsukise
- Journal Title
  
  J Histochem Cytochem
  
  Volume: 65 Pages: 637-653
- DOI
  10.1369/0022155417732527
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08078, KAKENHI-PROJECT-17K08528
[Journal Article] Expression of secretogranin III in chicken endocrine cells: its relevance to the secretory granule properties of peptide prohormone processing and bioactive amine content.2015
- Author(s)
  Gomi H, Morikawa S, Shinmura N, Moki H, Yasui T, Tsukise A, Torii S, Watanabe T, Maeda Y, Hosaka M
- Journal Title
  
  J. Histochem. Cytochem.
  
  Volume: 印刷中 Pages: 350-366
- DOI
  10.1369/0022155415575032
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390050, KAKENHI-PROJECT-25440052, KAKENHI-PROJECT-25450471
[Journal Article] Alexey Semyanov, Shigeyoshi Itohara, Astrocyte Ca^<2+> signals are required for the functional integrity oftripartite synapses2013
- Author(s)
  Mika Tanaka, Pei-Yu Shih, Hiroshi Gomi, Takamasa Yoshida, Junichi Nakai, Reiko Ando, Teiichi Furuichi, Katsuhiko Mikoshiba
- Journal Title
  
  Molecular Brain
  
  Volume: vol.6 Pages: 1-13
- URL
  http://www.molecularbrain.com/content/6/1/6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500367
[Journal Article] Involvement of cyclin-dependent kinase-like 2 in cognitive function required for contextual and spatial learning in mice2013
- Author(s)
  Hiroshi Gomi, Takayuki Sassa, Richard F. Thompson, Shigeyoshi Itohara
- Journal Title
  
  Frontiers in Behavioral Neuroscience
  
  Volume: vol.4 Pages: 1-14
- URL
  http://www.frontiersin.org/Behavioral_Neuroscience/10.3389/fnbeh.2010.00017/full
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500367
[Journal Article] Immunohistochemical analysis of I A-2 family of protein tyrosine phosphatases in rat gastrointestinal endocrine cells.2013
- Author(s)
  Gomi H
- Journal Title
  
  Journal of Histochemistry and Cytochemistry
  
  Volume: 61 Pages: 156-168
- DOI
  10.1369/0022155412466872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689007, KAKENHI-PROJECT-22500367, KAKENHI-PROJECT-24390050, KAKENHI-PROJECT-25450471
[Journal Article] Immunohistochemical analysis of IA-2 family of protein tyrosine phosphatases in rat gastrointestinal endocrine cells2013
- Author(s)
  Hiroshi Gomi, Chisato Kubota-Murata, Tadashi Yasui, Azuma Tsukise, Seiji Torii
- Journal Title
  
  Journal of Histochemistry & Cytochemistry
  
  Volume: vol.61 Pages: 156-168
- URL
  http://jhc.sagepub.com/content/61/2/156.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500367
[Journal Article] Histochemical distribution of sialic acids and antimicrobial substances in porcine carpal glands2012
- Author(s)
  Hiroshi Gomi
- Journal Title
  
  Arch Dermatol Res
  
  Volume: 304(Online first)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500367
[Journal Article] Involvement of cyclin-dependent kinase-like 2 in cognitive function required for contextual and spatial learning in mice2010
- Author(s)
  Hiroshi Gomi
- Journal Title
  
  Frontiers in Behavioral Neuroscience
  
  Volume: VOL.4 Pages: 1-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500367
[Journal Article] Docking is not a prerequisite but a temporal constraint for fusion of secretory granules2008
- Author(s)
  Kasai K, Fujita T, Gomi H, Izumi T
- Journal Title
  
  Traffic 9
  
  Pages: 1191-1203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390109
[Journal Article] Exophilin4/Slp2-a targets glucagon granUles to the plasma membrane through unique Ca^2+-inhibitory phospholipid-binding activity of the C2Adomain2007
- Author(s)
  Yu, M., Kasai, K., Nagashima, K., Torh, S., Yokota-Hashimoto, H., Okamoto, K., Takeuchi, T., Gomi, H., Izumi, T.
- Journal Title
  
  Molecular Biology of the Cell 18
  
  Pages: 688-696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390109
[Journal Article] Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane2007
- Author(s)
  Gomi, H., Mori, K., Itohara, S., Izumi, T.
- Journal Title
  
  Molecular Biology of the Cell 18
  
  Pages: 4377-4386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390109
[Journal Article] Secretory vesicle docking to the plasma Inembrane:molecUIar mechani2007
- Author(s)
  Izumi, T., Kasai, K., Gomi, H.
- Journal Title
  
  Diabetes Obesity Metabolism 9(spl.2)
  
  Pages: 109-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390109
[Journal Article] Secretory vesicle docking to the plasma membrane : molecular mechanism and functional significance2007
- Author(s)
  Izumi T, Kasai K, Gomi H
- Journal Title
  
  Diabetes Obesity and Metabolism 9(2)
  
  Pages: 109-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390109
[Journal Article] Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane2007
- Author(s)
  Gomi H, Mori K, Itohara S, Izumi T
- Journal Title
  
  Molecular Biology of the Cell 18(11)
  
  Pages: 4377-4386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390109
[Journal Article] Enhanced hippocampal neurodegeneration after traumatic or kinate excitotoxicity in GFAP-null mice2006
- Author(s)
  Otani, N., Nawashiro, H., Fukui, S., Shima K., Gomi, H., Brenner,M.
- Journal Title
  
  Journal of Clinical Neuroscience 13 (9)
  
  Pages: 934-938
- Data Source
  KAKENHI-PROJECT-17390109
[Journal Article] Chromosome 2 locus Nidd5 has a potent effect on adiposity in the TSOD mouse2006
- Author(s)
  Mizutani S, Gomi H, Hirayama I, Izumi T
- Journal Title
  
  Mammalian Genome 17(5)
  
  Pages: 375-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390109
[Journal Article] Enhanced hippocampal neurodegeneration after traumatic or kinate excitotoxicity in GFAP-null mice2006
- Author(s)
  Otani N, Nawashiro H, Fukui S, Shima K, Gomi H, Brenner M
- Journal Title
  
  Journal of Clinical Neuroscience 13(9)
  
  Pages: 934-938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390109
[Journal Article] Functional analysis of Rab27a effector granuphilin in insulin secretion2005
- Author(s)
  Izumi T, Gomi H, Torii S
- Journal Title
  
  Methods in Enzymology : GTPases Regulating Menmbrane Targeting and Fusion 403(18)
  
  Pages: 216-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390109
[Journal Article] Granuphilin molecularly docks insulin granules to the fusion machinery.2005
- Author(s)
  Gomi H., et al.
- Journal Title
  
  J. Cell. Biol. 171
  
  Pages: 99-109
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390261
[Journal Article] Granuphilin molecularly docks insulin granules to the fusion machinery.2005
- Author(s)
  Gomi H., et al.
- Journal Title
  
  J.Cell.Biol. 171
  
  Pages: 99-109
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390261
[Journal Article] Granuphilin molecularly docks insulin granules to the fusion machinery2005
- Author(s)
  Gomi H, Mizutani S, Kasai K, Itohara S, Izumi T
- Journal Title
  
  Journal of Cell Biology 171(1)
  
  Pages: 99-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390109
[Presentation] イヌ口腔腺におけるRabおよびSNAREタンパク質の発現解析2018
- Author(s)
  五味浩司、大澤裕美、宇野理恵、安井禎、鳥居征司、穂坂正博、月瀬東
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08078
[Presentation] イヌ涙腺における糖質ならびに免疫組織化学的解析2018
- Author(s)
  安井禎、五味浩司
- Organizer
  第161回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08078
[Presentation] 分泌顆粒蛋白質フォグリンによるインスリン分泌とシグナルの連結機構2018
- Author(s)
  久保田知里、齊藤直也、河野あゆみ、竹内利行、小林雅樹、北村忠弘、穂坂正博、五味浩司、鳥居征司
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K08078
[Presentation] シバヤギ耳道腺における抗菌物質と分泌制御タンパク質の免疫組織化学的解析2016
- Author(s)
  安井　禎、五味　浩司
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源科学部（神奈川県藤沢市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16K08078
[Presentation] ニワトリ内分泌器官におけるセクレトグラニンIIIの発現解析2016
- Author(s)
  五味　浩司、安井　禎、鳥居　征司、穂坂　正博
- Organizer
  第159回日本獣医学会学術集会
- Place of Presentation
  日本大学生物資源科学部（神奈川県藤沢市）
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-16K08078
[Presentation] Exophilin4/Slp2-a targetsglucagon granules to the plasma membrane throughunique Ca2^+-inhibitory phospholipid-binding activity of the C2A domain2007
- Author(s)
  Kasai, K., YU, M., Gomi, H., Izumi, T.
- Organizer
  第40回日本発生生物学会・第59回日本細胞生物学会合同大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-17390109
[Presentation] ラット腸管内分泌細胞におけるIA2チロシンホスファターゼ分子群の発現様式（Immunohistochemical analysis of IA2 family of protein-tyrosine phosphatases in rat gastrointestinal endocrine cells）
- Author(s)
  Hiroshi Gomi, Chisato Kubota-Murata, Seiji Torii
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25450471

1. TORII Seiji (40312904)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
2. IZUMI Testuro (00212952)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. ITOHARA Shigeyoshi (60252524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. NAMEKI Nobukazu (80302959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MOGAMI Hideo (90311604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 水谷伸 (20323371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 安井禎 (70434107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. HOSAKA Masahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
9. KOGA Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. BOCHIMOTO Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 渡部剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Gomi Hiroshi 五味 浩司

五味 浩司 ゴミ ヒロシ

GOMI Hiroshi 五味 浩司

Research Projects

Research Products

Co-Researchers

セクレトグラニンⅢの機能的多様性と疾患関連性の解析Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of formation and degradation mechanism of peptide hormone-containing secretory granules (the life of secretory granules)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of IA-2 family proteins in the endocrine cells of gastrointestinal tractPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Stabilizing endocrine cell function by phogrin.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of gliotransmittersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation and analysis of mice model for Alexander diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Visualization of insulin granules in pancreatic beta cells derived from genetically altered mouse models.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

多因子遺伝性糖尿病・肥満モデルマウスの成因遺伝子の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional Roles and Transcriptional Regulation of Cdkl2/KKIAMRE in Mouse BrainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脳の聴覚情報処理機構におけるアストログリアの役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Culture in 10% O2 enhances the production of active hormones in neuro-endocrine cells by up-regulating the expression of processing enzymes.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impaired processing of prohormones in secretogranin III-null mice causes maladaptation to an inadequate diet and stress.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The pseudophosphatase phogrin enables glucose-stimulated insulin signaling in pancreatic β cells.2018

Author(s)

Journal Title

DOI

Gomi Hiroshi 五味浩司

五味浩司ゴミヒロシ

GOMI Hiroshi 五味浩司