YAMAGISHI Takehiro 山岸丈洋

… Alternative Names

山岸丈洋ヤマギシタケヒロ

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Researcher Number	90297606
Other IDs
Affiliation (Current)	2025: 北海道科学大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2011: 東京薬科大学, 薬学部, 講師 2008: 東京薬科大学, 薬学部, 講師 2004 – 2005: 東京薬科大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Drug development chemistry Except Principal Investigator Drug development chemistry
Keywords	Principal Investigator γ-アミノ-β-アシルオキシホスホン酸 / ジオール / L-CPT I阻害剤 / II型糖尿病 / アシルカルニチン誘導体 / 等配置換 / 酵素阻害剤 / 糖尿病 / 有機化学 / 薬学 … More Except Principal Investigator … More PNP阻害剤 / スフィンゴミエリナーゼ / fragment-based drug design / ジフルオロホスホン酸 / ヌクレオチドアナログ / ジフルオロメチレンボスホン酸 / ホスフィン酸 / 速度論的光学分割 / ジペプチドイソスター / X線構造解析 / 遷移状態アナログ / ペプチドイソスター / Huisen反応 / Huisgen反応 / TP阻害剤 / Huisgen 反応 / クリック反応 / TP 阻害剤 / PNP 阻害剤 Less

Development of biologically active compounds based on features of phosphonyl and phosphinyl functional groups
- Principal Investigator
  
  YOKOMATSU Tsutomu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
Development of biologically active compounds based on features of fluoromethylene phosphonates
- Principal Investigator
  
  YOKOMATSU Tsutomu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
カルボン酸等価体を活用する糖尿病治療薬のデザイン・合成Principal Investigator
- Principal Investigator
  
  山岸丈洋
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science

All 2012 2011 2010 2009 2008 2006 2004

All Journal Article Presentation

[Journal Article] Diastereoselective synthesis of the Leu-Pro type phosphinyl dipeptide isostere2011
- Author(s)
  T. Yamagishi, N. Tashiro, and T. Yokomatsu
- Journal Title
  
  J. Org. Chem
  
  Volume: 76 Pages: 5472-5476
- Data Source
  KAKENHI-PROJECT-21590126
[Journal Article] Diastereoselective synthesis of the Leu-Pro type phosphinyl dipeptide isostere2011
- Author(s)
  T.Yamagishi, N.Tashiro, T.Yokomatsu
- Journal Title
  
  J.Org.Chem.
  
  Volume: 76 Issue: 13 Pages: 5472-5476
- DOI
  10.1021/jo200669r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590126
[Journal Article] A chemo-enzymatic synthesis of optically active 1,1-diethoxyethyl(amino-methyl)phosphinates : useful chiral building blocks for phosphinyl dipeptide isosteres2011
- Author(s)
  T.Yamagishi, J.Mori, T.Haruki, T.Yokomatsu
- Journal Title
  
  Tetrahedron : Asymmetry
  
  Volume: 22 Issue: 12 Pages: 1358-1363
- DOI
  10.1016/j.tetasy.2011.06.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590126
[Journal Article] A chemo-enzymatic synthesis of optically active 1, 1-diethoxyethyl(aminomethyl) phosphinates : useful chiral building blocks for phosphinyl dipeptide isosteres2011
- Author(s)
  T. Yamagishi, J. Mori, T. Haruki, and T. Yokomatsu
- Journal Title
  
  Tetrahedron : Asymmetry
  
  Volume: 22 Pages: 1358-1363
- Data Source
  KAKENHI-PROJECT-21590126
[Journal Article] Diastereoselective synthesis of γ-amino-δ-hydroxy-α, α-difluorophosphonates : A vehiclefor for the structure-activity relationship of SMA-7, a potent sphingomyelinase inhibitor2009
- Author(s)
  T.Yamagishi, T.Yokomatsu, 他
- Journal Title
  
  J Org.Chem. 74
  
  Pages: 6350-6353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590126
[Journal Article] Diastereoselective synthesis of γ-amino-δ-hydroxy-α, α-difluorophosphonates : A vehiclefor for the structure-activity relationship of SMA-7, a potent sphingomyelinase inhibitor2009
- Author(s)
  T. Yamagishi, S. Muronoi, S. Hikishima, H. Shimeno, S. Soeda, and T. Yokomatsu
- Journal Title
  
  J. Org. Chem
  
  Volume: 74 Pages: 6350-6353
- Data Source
  KAKENHI-PROJECT-21590126
[Journal Article] Asymmetric Synthesis of Phosphonic Acid Analogues For Acylcarnitine2006
- Author(s)
  Takehiro Yamagishi
- Journal Title
  
  Tetrahedron 62
  
  Pages: 54-65
- Data Source
  KAKENHI-PROJECT-16790087
[Journal Article] Symthesis of Chiral γ-Amino-β-hydroxyphosphonate Derivatives from Unsaturated Phosphonates2004
- Author(s)
  Yamagishi, T.et al.
- Journal Title
  
  Synlett
  
  Pages: 2505-2508
- Data Source
  KAKENHI-PROJECT-16790087
[Presentation] ホスフィニルジペプチイソスターの効率的合成を指向したアミノメチルホスフィナートの不斉アシル化反応2012
- Author(s)
  春木晶充, 森淳一郎, 山岸丈洋, 横松力
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21590126
[Presentation] ホスフィニルジペプチイソスターの効率的合成を指向したアミノメチルホスフィナートの不斉アシル化反応2012
- Author(s)
  春木晶充, 森淳一郎, 山岸丈洋
- Organizer
  日本薬学会第132年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21590126
[Presentation] 非天然型の立体配置を有するホスフィニルジペプチドイソスターの合成研究2011
- Author(s)
  春木晶充, 山岸丈洋, 横松力
- Organizer
  日本薬学会第132年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21590126
[Presentation]2010
- Author(s)
  T. Haruki, H. Ichikawa, J. Mori, T. Yamagishi, T. Yokomatsu
- Organizer
  18^<th> International Conference on Phosphorus Chemistry
- Place of Presentation
  Wroclaw, Poland
- Data Source
  KAKENHI-PROJECT-21590126
[Presentation] SMase阻害剤を指向した新規SMA-7類縁体の合成研究2009
- Author(s)
  野田祐介, 室野井真, 疋島貞雄, 山岸丈洋, 横松力
- Organizer
  第35回反応と合成の進歩シンポジウム
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-21590126
[Presentation] SMase阻害剤SMA-7誘導体の新規合成法の開発2008
- Author(s)
  室野井真, 山岸丈洋, 疋島貞雄, 横松力
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590109

1. YOKOMATSU Tsutomu (70158369)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. HIKISHIMA Sadao (70398816)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. ANGIESKA Bzowska

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SOEDA Shinji (20078695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TACHIBANA Masumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YATSU Tomoyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NODA Yusuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMAGISHI Takehiro 山岸 丈洋

山岸 丈洋 ヤマギシ タケヒロ

Research Projects

Research Products

Co-Researchers

Development of biologically active compounds based on features of phosphonyl and phosphinyl functional groups

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of biologically active compounds based on features of fluoromethylene phosphonates

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

カルボン酸等価体を活用する糖尿病治療薬のデザイン・合成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Diastereoselective synthesis of the Leu-Pro type phosphinyl dipeptide isostere2011

Author(s)

Journal Title

Data Source

[Journal Article] Diastereoselective synthesis of the Leu-Pro type phosphinyl dipeptide isostere2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A chemo-enzymatic synthesis of optically active 1,1-diethoxyethyl(amino-methyl)phosphinates : useful chiral building blocks for phosphinyl dipeptide isosteres2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A chemo-enzymatic synthesis of optically active 1, 1-diethoxyethyl(aminomethyl) phosphinates : useful chiral building blocks for phosphinyl dipeptide isosteres2011

Author(s)

Journal Title

Data Source

[Journal Article] Diastereoselective synthesis of γ-amino-δ-hydroxy-α, α-difluorophosphonates : A vehiclefor for the structure-activity relationship of SMA-7, a potent sphingomyelinase inhibitor2009

Author(s)

Journal Title

Data Source

[Journal Article] Diastereoselective synthesis of γ-amino-δ-hydroxy-α, α-difluorophosphonates : A vehiclefor for the structure-activity relationship of SMA-7, a potent sphingomyelinase inhibitor2009

Author(s)

Journal Title

Data Source

[Journal Article] Asymmetric Synthesis of Phosphonic Acid Analogues For Acylcarnitine2006

Author(s)

Journal Title

Data Source

[Journal Article] Symthesis of Chiral γ-Amino-β-hydroxyphosphonate Derivatives from Unsaturated Phosphonates2004

Author(s)

Journal Title

Data Source

[Presentation] ホスフィニルジペプチイソスターの効率的合成を指向したアミノメチルホスフィナートの不斉アシル化反応2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ホスフィニルジペプチイソスターの効率的合成を指向したアミノメチルホスフィナートの不斉アシル化反応2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 非天然型の立体配置を有するホスフィニルジペプチドイソスターの合成研究2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation]2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] SMase阻害剤を指向した新規SMA-7類縁体の合成研究2009

Author(s)

YAMAGISHI Takehiro 山岸丈洋

山岸丈洋ヤマギシタケヒロ