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Takahara Kazuhiko  高原 和彦

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… Alternative Names

高原 和彦  タカハラ カズヒコ

TAKAHARA Kazuhiko  高原 和彦

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Researcher Number 90301233
Other IDs
External Links
Affiliation (Current) 2025: 京都大学, 生命科学研究科, 准教授
Affiliation (based on the past Project Information) *help 2023: 京都大学, 生命科学研究科, 准教授
2020 – 2021: 京都大学, 生命科学研究科, 准教授
2015 – 2018: 京都大学, 生命科学研究科, 准教授
2014: 京都大学, 大学院生命科学研究科, 講師
2004 – 2014: KYOTO UNIVERSITY, Lab.of Immunobiol., Dep.of Animal Development and Physiology, Division of Systemic Life Science, Graduate School of Biostudies, Lecturer, 生命科学研究科, 講師 … More
2012: 京都大学, 大学院・生命科学研究科, 講師
2002 – 2004: Lab. of Immunobiol., Dep. of Animal Development and Physiology, Division of Systemic Life Science, Lecturer, 大学院・生命科学研究科, 講師
2001: Graduate School of Biostudies, Dept. Animal Dev. Physiol., KYOTO UNIVERSITY, Instructor, 大学院・生命化学研究科, 助手
2001: 京都大学, 生命科学研究科, 助手
1999 – 2001: 京都大学, 大学院・生命科学研究科, 助手
1998: 京都大学, 大学院・理学研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Experimental pathology / Biological Sciences / Experimental pathology / Basic Section 49030:Experimental pathology-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields
Except Principal Investigator
Biological Sciences / Experimental pathology / Experimental pathology / Immunology / General pharmacology
Keywords
Principal Investigator
レクチン / 樹状細胞 / 糖鎖 / マクロファージ / 酵母 / 微生物 / ランゲルハンス細胞 / Candida albicans / zymosan / 敗血症 … More / 免疫抑制 / IL-10 / C型レクチン / C. albicans / 単球 / TLR2 / グラム陰性菌 / TLR4 / ランゲリン / TGF-β / 微生物糖鎖 / C-type lectin / Langerin / Langerhans cells / FISH / 免疫制御 / TLR / モノクローナル抗体 / 感染症 / C.albicans / サイトカインストーム / 合成糖鎖 / ワクチン / IFN-gamma / 免疫賦活 / lipopolysaccharide / cytokine / Gram-negative bacteria / macrophage / lectin / DC-SIGN / Zymosan / RAW264.7 / リボ多糖 / サイトカイン / Phagocytosis / Microbe recognition / Dendritic cells / 微生物認識 / 捕捉活性 / mannan / dendritic cells / 多重体 / マンナン / 細胞 / 免疫学 / 単クローン抗体 / CD14 / Toll-like receptor / 菌糸型 / リポ多糖 / Ngaマウス / NC / マトリックス / アレルギー発症 / Tolloid-like gene / マトリックス再構築 / PCPE / PCP / BMP-1 / TGF-β1 / 皮膚炎症 … More
Except Principal Investigator
樹状細胞 / サブセット / T細胞活性化 / Th2 / Th1 / 抗原提示 / クロスプレゼンテイーション / 抗原捕捉 / Subsets / T cell activation / Dendritic cells / 細胞分化 / 炎症 / マクロファージ / 食作用 / 免疫応答制御 / 免疫寛容 / Cross presentation / Antigen capture / Differentiation / Immune regulation / クロスプレゼンティーション / 免役応答制御 / Phenotype / Antigen presentation / Maturation / Development / 細胞間相互作用 / 抗原プロセッシング / MHCクラスII分子 / 単球 / 免疫制御 / TH2 / TH1 / 腫瘍細胞 / アポトーシス / IL-12 / 接触過敏応答 / ランゲリン / ランゲルハンス細胞 / 表現型 / 亜集団 / 成熟 / 尿酸結晶 / アミロイド-beta / IL-1beta / 原子間力顕微鏡 / アミロイド-b / マイクログリア / 凝集体 / アミロイド β / IL-1β / 微細粒子 / ラテックスビーズ / サイトカイン / サイズ効果 / ナノ粒子 / 繊維芽細胞 / 線維芽細胞 / 内皮細胞 / ナノ / 肺 / 死細胞 / 細胞亜集団 / 樹状細胞活性化 / IFN-γ / T細胞除去 / T細胞増殖 / 86 / CD80 / CD25^+CD4^+制御性T細胞 / 補助刺激分子 / クロストプライミング / クロストレランス / 抗原特異性 / 制御性T細胞 / クロスプレゼンテーション Less
  • Research Projects

    (22 results)
  • Research Products

    (63 results)
  • Co-Researchers

    (5 People)
  •  Development of anti-cytokine storm polysacharides based on immunosuppressive activities of pathogensPrincipal Investigator

    • Principal Investigator
      Takahara Kazuhiko
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Kyoto University
  •  自然免疫系レセプターの胎生期リンパ球発生における新たな働きPrincipal Investigator

    • Principal Investigator
      高原 和彦
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Kyoto University
  •  Immune control by polysaccharides derived from microbesPrincipal Investigator

    • Principal Investigator
      Takahara Kazuhiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Kyoto University
  •  Immune regulation though C-type lectin using microbial polysaccharidesPrincipal Investigator

    • Principal Investigator
      Takahara Kazuhiko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Kyoto University
  •  IL-1beta production depending on size of insoluble material generated in vivo

    • Principal Investigator
      INABA Kayo
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Kyoto University
  •  Biological studies of size-effect by nano-particles

    • Principal Investigator
      INABA Kayo
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Kyoto University
  •  糖鎖認識におけるSIGNR1と他のファミリー分子における差異の解析Principal Investigator

    • Principal Investigator
      高原 和彦
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Observation of in vivo dynamics of macrophage subsets based on expression of lectin moleculePrincipal Investigator

    • Principal Investigator
      TAKAHARA Kazuhiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Kyoto University
  •  ナノ物質に対する細胞応答性とその差異の検討

    • Principal Investigator
      稲葉 カヨ
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto University
  •  微生物感染におけるSIGNR1の働きPrincipal Investigator

    • Principal Investigator
      高原 和彦
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Functional analyses of mouse lectin SIGNR familyPrincipal Investigator

    • Principal Investigator
      TAKAHARA Kazuhiko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Kyoto University
  •  Microbe recognition and effect on TLR response by C-type lection expressing in immune cells.Principal Investigator

    • Principal Investigator
      TAKAHARA Kazuhiko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Kyoto University
  •  マウスレクチンSIGNR1の微生物認識およびTLR4との相互作用Principal Investigator

    • Principal Investigator
      高原 和彦
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Microbes and polysaccharide recognition of LangerinPrincipal Investigator

    • Principal Investigator
      TAKAHARA Kazuhiko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      KYOTO UNIVERSITY
  •  Function of Dendritic cells as Sentinel and Regulator

    • Principal Investigator
      INABA Kayo
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      KYOTO UNIVERSITY
  •  抗原提示細胞によるT細胞活性化機構

    • Principal Investigator
      稲葉 カヨ
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  免疫寛容の誘導・維持と破綻における樹状細胞の機能と作用メカニズムの解析

    • Principal Investigator
      稲葉 カヨ
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  抗腫瘍免疫応答における樹状細胞の役割

    • Principal Investigator
      稲葉 カヨ
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Behavior and function of mouse Langerin^+ cells in skin and mucosa.Principal Investigator

    • Principal Investigator
      TAKAHARA Kazuhiko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      KYOTO UNIVERSITY
  •  マウス系統間における皮膚炎症応答の違いとアレルギー獲得性の相関Principal Investigator

    • Principal Investigator
      高原 和彦
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Myeloid dendritic cells and lymphoid dendritic cells

    • Principal Investigator
      INABA Kayo
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      KYOTO UNIVERSITY
  •  炎症領域におけるTGF-β1のランゲルハンス細胞及び樹状細胞に対する影響Principal Investigator

    • Principal Investigator
      高原 和彦
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Kyoto University

All 2017 2016 2015 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book

  • [Book] 臨床免疫・アレルギー科(C型レクチンによる生体応答制御-恒常性の維持と応用-)2016

    • Author(s)
      高原 和彦
    • Total Pages
      7
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-16K08737
  • [Journal Article] Cystine uptake through the cystine/glutamate antiporter xCT triggers glioblastoma cell death under glucose deprivation2017

    • Author(s)
      Goji, T., Takahara, K., Negishi, M. and Katoh, H.
    • Journal Title

      J. Biol. Chem.

      Volume: 292 Issue: 48 Pages: 19721-19732

    • DOI

      10.1074/jbc.m117.814392

    • NAID

      120006482852

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08737, KAKENHI-PROJECT-15K07043, KAKENHI-PROJECT-15K07928
  • [Journal Article] Absence of DCIR1 reduces the rate of endotoxemic hepatitis in mice.2017

    • Author(s)
      Ishiguro T, Fukawa T, Akaki K, Nagaoka K, Takeda T, Iwakura Y ,Inaba K, Takahara K.
    • Journal Title

      Eur J Immunol.

      Volume: 47 Issue: 4 Pages: 704-712

    • DOI

      10.1002/eji.201646814

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16K08737
  • [Journal Article] Amyloid β oligomers induce interleukin-1β production in primary microglia in a cathepsin B- and reactive oxygen species-dependent manner2015

    • Author(s)
      Taneo, J., Adachi, T., Yoshida, A., Takeyasu, K.,Takahara, K. and Inaba, K.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 458 Issue: 3 Pages: 561-567

    • DOI

      10.1016/j.bbrc.2015.02.006

    • NAID

      120005575184

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460494, KAKENHI-PROJECT-25670192
  • [Journal Article] Dendritic cell immunoreceptor 1 alters neutrophil responses in the development of experimental colitis.2015

    • Author(s)
      Tokieda, S., Komori, M., Ishiguro, Iwakura, Y., Takahara, K.* and Inaba, K.
    • Journal Title

      BMC Immunol.

      Volume: 16 Issue: 1 Pages: 64-64

    • DOI

      10.1186/s12865-015-0129-5

    • NAID

      120005689211

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460494, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] In vivo and in vitro analyses of a-galactosylceramide uptake by conventional dendritic cell subsets using its fluorescence-labeled derivative.2015

    • Author(s)
      Ushida, M., Iyoda, T., Kanamori, M., Watarai, H., Takahara, K.* and Inaba, K.
    • Journal Title

      Immunol. Lett.

      Volume: 168 Issue: 2 Pages: 300-5

    • DOI

      10.1016/j.imlet.2015.10.008

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460494
  • [Journal Article] Particle size of latex beads dictates IL-1β production mechanism2013

    • Author(s)
      Adachi, T., Takahara, K., Taneo, J., Uchiyama, Y. and Inaba, K.
    • Journal Title

      Plos One

      Volume: 8 Issue: 7 Pages: e68499-e68499

    • DOI

      10.1371/journal.pone.0068499

    • NAID

      120005307064

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670192
  • [Journal Article] Efficient capture of C. albicans and zymosan by SIGNR1 facilitates TLR2-dependent TNF-α production by macrophages2012

    • Author(s)
      Takahara, K.
    • Journal Title

      Int.Immunol.

      Volume: 24 Issue: 2 Pages: 89-96

    • DOI

      10.1093/intimm/dxr103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590417, KAKENHI-PROJECT-23659203
  • [Journal Article] Difference in fine specificity to polysaccharides of C. albicans mannoprotein between mouse SIGNR1 and human. DC-SIGN.2012

    • Author(s)
      Takahara, K., Tokieda, S., Nagaoka, K., Takeda, T., Kimura, Y. and Inaba, K
    • Journal Title

      Infect. Immun

      Volume: 41 Pages: 1435-44

    • Data Source
      KAKENHI-PROJECT-21590417
  • [Journal Article] IRF-2 regulates B cell proliferation and antibody production through distinctmechanisms.2012

    • Author(s)
      Minamoto K, Takahara K, Adachi T, Nagaoka K, Iyoda T, Taki S,Inaba K
    • Journal Title

      Int Immunol

      Volume: 24 Issue: 9 Pages: 573-581

    • DOI

      10.1093/intimm/dxs060

    • NAID

      120005302075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390149, KAKENHI-PROJECT-23659203
  • [Journal Article] Difference in fine specificity to polysaccharides of C.albicans mannoprotein between mouse SIGNR1 and human DC-SIGN2012

    • Author(s)
      Takahara, K.
    • Journal Title

      Infect.Immun.

      Volume: 80 Issue: 5 Pages: 1699-1706

    • DOI

      10.1128/iai.06308-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21370062, KAKENHI-PROJECT-21590417, KAKENHI-PROJECT-23659203
  • [Journal Article] Efficient capture of C. albicans and zymosan by SIGNR1 facilitates TLR2-dependent TNF-αproduction by macrophages.2012

    • Author(s)
      Takahara, K., Tokieda, S., Nagaoka, K. and Inaba, K
    • Journal Title

      Int. Immunol

      Volume: 24 Pages: 89-96

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659203
  • [Journal Article] Efficient capture of Calbicans and zymosan by SIGNR1 facilitates TLR2-dependent TNF-αproduction by macrophages2012

    • Author(s)
      Takahara, K., Tokieda, S., Nagaoka, K. and Inaba, K
    • Journal Title

      Int. Immunol

      Volume: 24 Pages: 89-96

    • Data Source
      KAKENHI-PROJECT-21590417
  • [Journal Article] C-type lectin SIGNR1 enhances cellular oxidative burst response against C. albicans in cooperation with Dectin-1.2011

    • Author(s)
      Takahara, K., Tokieda, S., Nagaoka, K., Takeda, T., Kimura, Y. and Inaba, K
    • Journal Title

      Eur. J. Immunol

      Volume: 88 Pages: 913-924

    • Data Source
      KAKENHI-PROJECT-21590417
  • [Journal Article] C-type lectin SIGNR1 enhances cellular oxidative burst response against C.albicans in cooperation with Dectin-12011

    • Author(s)
      Kazuhiko Takahara, et al.
    • Journal Title

      Eur.J.Immunol.

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590417
  • [Journal Article] GM-CSF-independent CD1a expression in epidermal Langerhans cells : evidence from human CD1A genome-transgenic mice.2011

    • Author(s)
      Kobayashi, C., Shiina, T., Tokioka, A., Hattori, Y., Komori, T., Kobayashi-Miura, M., Takizawa, T., Takahara, K., Inaba, K., Inoko, H., Takeya, M., Dranoff, G. and Sugita, M.
    • Journal Title

      J. Invest. Dermatol.

      Volume: 132 Pages: 241-244

    • Data Source
      KAKENHI-PROJECT-21590417
  • [Journal Article] GM-CSF-Independent CD1a Expression in Epidermal Langerhans Cells : Evidence from Human CD1A Genome-Transgenic Mice2011

    • Author(s)
      Kobayashi Chisa; Shiina Takashi; Tokioka Atsuko, et al
    • Journal Title

      JOURNAL OF INVESTIGATIVE DERMATOLOGY

      Volume: 132:1 Issue: 1 Pages: 241-244

    • DOI

      10.1038/jid.2011.280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19101008, KAKENHI-PROJECT-21390304, KAKENHI-PROJECT-21590417, KAKENHI-PLANNED-22133002, KAKENHI-PROJECT-23390191, KAKENHI-PROJECT-23659203
  • [Journal Article] C-type lectin SIGNR1 enhances cellular oxidative burst response against C.albicans in cooperation with Dectin-12011

    • Author(s)
      Kazuhiko Takahara, et al.
    • Journal Title

      Eur.J.Immunol.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21022021
  • [Journal Article] Expression of C-type lectin, SIGNR3, on subsets of dendritic cells, macrophages and monocytes2010

    • Author(s)
      Nagaoka, K., Takahara, K., Minamino, K., Takeda, T., Yoshida, Y. and Inaba, K
    • Journal Title

      J. Leukoc. Biol

      Volume: 88 Pages: 913-924

    • Data Source
      KAKENHI-PROJECT-21590417
  • [Journal Article] Mycobacterium abscessus activates the macrophage innate immune response via a physical and functional interaction between TLR2 and dectin-12008

    • Author(s)
      Shin DM, Yang CS, Yuk JM, Lee JY, Kim KH, Shin SJ, Takahara K, Lee SJ, Jo EK.
    • Journal Title

      Cell Microbiol

      Pages: 1608-1621

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590389
  • [Journal Article] C-type lectins on dendritic cells and macrophages.2006

    • Author(s)
      Takahara, K.
    • Journal Title

      Proceeding of International Symposium on Low-dose Radiation Exposures and Bio-Defence System. (印刷中)

    • Data Source
      KAKENHI-PROJECT-16017245
  • [Journal Article] C-type lectins on dendritic cells and macrophages.2006

    • Author(s)
      Takahara, K.
    • Journal Title

      Proceeding of International Symposium on Low-dose Radiation Exposures and Bio-Defence System. (印刷中)

    • Data Source
      KAKENHI-PROJECT-17590342
  • [Journal Article] Association of SIGNR1 with TLR4/MD-2 enhances signal transduction by recognition of LPS in Gram-negative bacteria.2005

    • Author(s)
      Koji Nagaoka, Kazuhiko Takahara, Kay Tanaka, Hideo Yoshida, 1 Ralph M.Steinman, Shin-ichiro Saitoh, Sachiko Akashi-Takamura, Kensuke Miyake, Young Sun Kang, Chae Gyu Park, Kayo Inaba
    • Journal Title

      Int Immunol. 17(7)

      Pages: 827-36

    • NAID

      10019357724

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590342
  • [Journal Article] Association of SIGNR1 with TLR4/MD-2 enhances signal transduction by recognition of LPS in Gram-negative bacteria. (^* the authors contributed equally to this work).2005

    • Author(s)
      Nagaoka, K.^*, Takahara, K.^*, Tanaka, K., Yoshida, H., Steinman, R.M., Saitoh, S., Akashi-Takamura, S., Miyake, K., Kang, Y.S., Park, C.G., Inaba, K.
    • Journal Title

      Int.Immunol. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590336
  • [Journal Article] C-type lectins on dendritic cells and macrophages.2005

    • Author(s)
      Takahara, K.
    • Journal Title

      Proceeding of International Symposium on Low-dose Radiation Exposures and Bio-Defense System

      Pages: 55-58

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590342
  • [Journal Article] Initial functional comparison of the mDC-SIGN, SIGNR1,SIGNR3 and Langerin, mouse C-type lectin2004

    • Author(s)
      Takahara, K.
    • Journal Title

      Int.Immunol. 16・6

      Pages: 819-829

    • Data Source
      KAKENHI-PROJECT-16017245
  • [Journal Article] Initial functional comparison of the mDC-SIGN, SIGNR1, SIGNR3 and Langerin, mouse C-type lectin2004

    • Author(s)
      Takahara, K.
    • Journal Title

      Int.Immunol. 16・6

      Pages: 819-829

    • Data Source
      KAKENHI-PROJECT-15590336
  • [Journal Article] Defective development of splenic and epidermal CD4+ dendritic cells in mice deficient for IFN regulatory factor-2.2004

    • Author(s)
      Ichikawa, E., Hida, S., Omatsu, Y., Shimoyama, S., Takahara, K., Miyagawa.S., Inaba, K., Taki, S.
    • Journal Title

      Proc.Natl.Acad.Sci.U.S.A. 101

      Pages: 3909-3914

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590336
  • [Journal Article] Functional comparison of the mouse DC-SIGN, SIGNR1, SIGNR3 and Langerin, C-type lectins2004

    • Author(s)
      Takahara, K.
    • Journal Title

      Int.Immunol. 16(6)

      Pages: 819-829

    • NAID

      10013085962

    • Data Source
      KAKENHI-PROJECT-13140202
  • [Journal Article] Functional comparison of the mDC-SIGN, SIGNR1, SIGNR3 and Langerin, mouse C-type lectin2004

    • Author(s)
      Takahara, K.
    • Journal Title

      Int.Immunol. 16・6

      Pages: 819-829

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590336
  • [Journal Article] Functional comparison of the mouse DC-SIGN, SIGNR1, SIGNR3 and Langerin, C-type lectins. (^* the authors contributed equally to this work).2004

    • Author(s)
      Takahara, K.^*, Yashima, Y.^*, Yoshida, H, Kimura, Y, Kang, Y.-S., Steinman, R.M., Park, C.G., Inaba, K.
    • Journal Title

      Int.Immunol 16

      Pages: 819-829

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590336
  • [Journal Article] A novel C-type lectin expressed by marginal zone macro-phages in spleen, mediates uptake of the polysaccharide dextran. (^* the authors contributed equally to this work).2003

    • Author(s)
      Kang, Y.-S., Yamazaki, S.^*, Iyoda, T.^*, Pack, M., Bruening, S.A., Kim, J.Y., Takahara, K., Inaba, K., Steinman, R.M., Park, C.G.
    • Journal Title

      Int.Immunol. 15

      Pages: 177-186

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590336
  • [Journal Article] Transforming growth factor-b induces secretion of activated ADAMTS-2 : A procollagen III N-proteinase.2003

    • Author(s)
      Wang, W.-M., Lee, S., Steiglitz, B.M., Scott, I.C., Lebares, C.C., Allen, L, Brenner, M.C., Takahara, K., Greenspan, D.S.
    • Journal Title

      J.Biol.Chem. 278

      Pages: 19549-19557

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590336
  • [Presentation] Amelioration of DSS-induced colitis in DCIR1-deficient mice2016

    • Author(s)
      TAKAHARA Kazuhiko, IWAKURA Yoichiro, INABA Kayo
    • Organizer
      日本免疫学会総会・学術終会
    • Place of Presentation
      沖縄コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-16K08737
  • [Presentation] Amyloid b oligomers, but not fibrils, induced IL-1b production by mouse microglia2013

    • Author(s)
      Takumi Adachi, Kazuhiko Takahara, Jun Taneo and Kayo Inaba
    • Organizer
      日本免疫学会
    • Place of Presentation
      千葉、幕張
    • Data Source
      KAKENHI-PROJECT-25670192
  • [Presentation] N-glycan of C. albicans mannoprotein effectively induces IL-10 production in the presence of LPS2013

    • Author(s)
      高原 和彦
    • Organizer
      日本免疫学会
    • Place of Presentation
      千葉、幕張
    • Data Source
      KAKENHI-PROJECT-25460494
  • [Presentation] Distinctive IL-1β production mechanisms depending on nano- and micro-size particles2012

    • Author(s)
      足立 匠、高原 和彦、種子尾 潤、稲葉 カヨ
    • Organizer
      日本免疫学会
    • Place of Presentation
      神戸
    • Year and Date
      2012-12-06
    • Data Source
      KAKENHI-PROJECT-23659203
  • [Presentation] Human C-type lectin DC-SIGN recognizes C. albicans more efficiently than S. cerevisiae and produces a large amount of IL-102012

    • Author(s)
      高原 和彦、稲葉 カヨ
    • Organizer
      日本免疫学会
    • Place of Presentation
      神戸
    • Year and Date
      2012-12-05
    • Data Source
      KAKENHI-PROJECT-23659203
  • [Presentation] 粒子サイズによる細胞応答性の差異 -細胞には粒子の大きさに依存した応答経路が存在する-2012

    • Author(s)
      高原 和彦、足立 匠、種子尾 潤、稲葉 カヨ
    • Organizer
      ナノ材料の安全性・社会受容に関するシンポジウム(招待講演)
    • Place of Presentation
      京都リサーチパーク
    • Year and Date
      2012-01-24
    • Data Source
      KAKENHI-PROJECT-23659203
  • [Presentation] 粒子サイズによる細胞応答性の差異-細胞には粒子の大きさに依存した応答経路が存在する2012

    • Author(s)
      高原和彦
    • Organizer
      ナノ材料の安全性・社会受容に関するシンポジウム
    • Place of Presentation
      京都リサーチパーク(京都府)(招待講演)
    • Year and Date
      2012-01-24
    • Data Source
      KAKENHI-PROJECT-21590417
  • [Presentation] IRF-2 controls antibody production through upregulation of Blimp-1 and class switch recombination2012

    • Author(s)
      南野 研人、高原 和彦、足立 匠、長岡 孝治、伊豫田 智典、瀧 伸介、稲葉 カヨ
    • Organizer
      日本免疫学会
    • Place of Presentation
      神戸
    • Year and Date
      2012-12-07
    • Data Source
      KAKENHI-PROJECT-23659203
  • [Presentation] C型レクチンSIGNR1はDectin-1と共同して細胞のoxidative burstを促進する2011

    • Author(s)
      高原和彦
    • Organizer
      日本免疫学会
    • Place of Presentation
      幕張
    • Year and Date
      2011-11-28
    • Data Source
      KAKENHI-PROJECT-21590417
  • [Presentation] C型レクチンSIGNR1はDectin-1と共同して細胞のoxidative burstを促進する2011

    • Author(s)
      高原 和彦
    • Organizer
      日本免疫学会
    • Place of Presentation
      幕張メッセ(千葉)
    • Data Source
      KAKENHI-PROJECT-23659203
  • [Presentation] C型レクチンSIGNR1はDectin-1と共同して細胞のoxidative burstを促進する2011

    • Author(s)
      高原 和彦、時枝 純佳、稲葉 カヨ
    • Organizer
      日本免疫学会
    • Place of Presentation
      幕張メッセ(千葉)
    • Year and Date
      2011-11-28
    • Data Source
      KAKENHI-PROJECT-23659203
  • [Presentation] C型レクチンSIGNR1はDectin-1と共同して細胞のoxidative burstを促進する2011

    • Author(s)
      高原和彦
    • Organizer
      日本免疫学会
    • Place of Presentation
      幕張メッセ(千葉県)
    • Year and Date
      2011-11-28
    • Data Source
      KAKENHI-PROJECT-21590417
  • [Presentation] Recognition of Calbicans by SIGNR1 and subsequent responses in vivo2010

    • Author(s)
      Kazuhiko Takahara
    • Organizer
      10th Awaji International Forum for Infection and Immunity
    • Place of Presentation
      淡路
    • Year and Date
      2010-09-09
    • Data Source
      KAKENHI-PROJECT-21590417
  • [Presentation] Recognition of C.albicans by SIGNR1 and subsequent responses in vivo2010

    • Author(s)
      Kazuhiko Takahara, et al.
    • Organizer
      10th Awaji International Forum for Infection and Immunity
    • Place of Presentation
      淡路
    • Year and Date
      2010-09-09
    • Data Source
      KAKENHI-PUBLICLY-21022021
  • [Presentation] Recognition of C.albicans by SIGNR1 and subsequent responses in vivo2010

    • Author(s)
      Kazuhiko Takahara, et al.
    • Organizer
      10th Awaji International Forum for Infection and Immunity
    • Place of Presentation
      淡路
    • Year and Date
      2010-09-09
    • Data Source
      KAKENHI-PROJECT-21590417
  • [Presentation] Role of SIGN-related molecules in innate immune responses2009

    • Author(s)
      高原和彦
    • Organizer
      CREST国際シンポジウム「獲得免疫と糖鎖生物学」
    • Place of Presentation
      かずさ
    • Year and Date
      2009-03-24
    • Data Source
      KAKENHI-PROJECT-19041036
  • [Presentation] Determination of polysaccharides on C. albicans mannoprotein recognized by human C-type lectin, DC-SIGN2009

    • Author(s)
      Kazuhiko Takahara, et al.
    • Organizer
      9th Awaji International Forum for Infection and Immunity
    • Place of Presentation
      淡路
    • Year and Date
      2009-09-08
    • Data Source
      KAKENHI-PROJECT-20659036
  • [Presentation] Role of SIGN-related molecules in innate immune responses2009

    • Author(s)
      高原和彦
    • Organizer
      CREST国際シンポジウム「獲得免疫と糖鎖生物学」
    • Place of Presentation
      かずさ
    • Year and Date
      2009-03-24
    • Data Source
      KAKENHI-PROJECT-19590389
  • [Presentation] Determination of polysaccharides on C.albicans mannoprotein recognized by human C-type lectin, DC-SIGN.2009

    • Author(s)
      Kazuhiko Takahara, et al.
    • Organizer
      9th Awaji International Forum for Infection and Immunity
    • Place of Presentation
      淡路夢舞台国際会議場(兵庫県)(招待講演)
    • Year and Date
      2009-09-08
    • Data Source
      KAKENHI-PUBLICLY-21022021
  • [Presentation] Determination of polysaccharides on C.albicans mannoprotein recognized by human C-type lectin, DC-SIGN.2009

    • Author(s)
      Kazuhiko Takahara, et al.
    • Organizer
      9th Awaji International Forum for Infection and Immunity
    • Place of Presentation
      淡路
    • Year and Date
      2009-09-08
    • Data Source
      KAKENHI-PROJECT-21590417
  • [Presentation] C-type lectin SIGNRI recognizing N-glycan α-mannan enhances nitric oxide production and candidacidal activity of RAW264.7 cells against C. albicans2008

    • Author(s)
      高原和彦
    • Organizer
      The Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路島
    • Year and Date
      2008-09-09
    • Data Source
      KAKENHI-PROJECT-19041036
  • [Presentation] C-type lectin SIGNRl recognizing N-glycan α-mannan enhances nitric oxide production and candidacidal activity of RAW264. 7 cells against C, albicans2008

    • Author(s)
      高原和彦
    • Organizer
      The Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路島
    • Year and Date
      2008-09-09
    • Data Source
      KAKENHI-PROJECT-19590389
  • [Presentation] C-type lectin SIGNR1 recognizing N-glycan α-mannan enhances nitric oxide production and candidacidal activity of RAW264.7 cells against C. albicans2008

    • Author(s)
      高原和彦
    • Organizer
      The Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路島
    • Year and Date
      2008-09-09
    • Data Source
      KAKENHI-PROJECT-19590389
  • [Presentation] Recognition property of SIGNR1 for C. albicans mannoprotein to enhances TNF- α production and candidacidal activity2008

    • Author(s)
      高原和彦
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2008-12-02
    • Data Source
      KAKENHI-PROJECT-19590389
  • [Presentation] Recognition property of SIGNRl for C. albicans mannoprotein to enhances TNF-α production and candidacidal activity2008

    • Author(s)
      高原和彦
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2008-12-02
    • Data Source
      KAKENHI-PROJECT-19590389
  • [Presentation] Recognition property of SIGNRI for C. albicans mannoprotein to enhances TNF-α production and candidacidal activity2008

    • Author(s)
      高原和彦
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2008-12-02
    • Data Source
      KAKENHI-PROJECT-19041036
  • [Presentation] Role of SIGNR1 in the recognition and response to pathogenic fungus2007

    • Author(s)
      高原和彦
    • Organizer
      The Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路島
    • Year and Date
      2007-09-04
    • Data Source
      KAKENHI-PROJECT-19590389
  • [Presentation] Role of SIGNR1 in the recognition and response to pathogenic fungus2007

    • Author(s)
      高原 和彦
    • Organizer
      The Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路島
    • Year and Date
      2007-09-04
    • Data Source
      KAKENHI-PROJECT-19041036
  • [Presentation] Cytokine productions of various cell types by nanomaterials in comparison with asbestos2007

    • Author(s)
      高原 和彦
    • Organizer
      日本免疫毒性学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2007-09-21
    • Data Source
      KAKENHI-PROJECT-19041036
  • [Presentation] 各種名の物質およびアスベストによる細胞のサイトカイン産生2007

    • Author(s)
      高原和彦
    • Organizer
      日本免疫毒性学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2007-09-21
    • Data Source
      KAKENHI-PROJECT-19590389
  • 1.  INABA Kayo (00115792)
    # of Collaborated Projects: 18 results
    # of Collaborated Products: 21 results
  • 2.  伊豫田 智典 (60359784)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  OKA Akira
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  瀧 伸介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  岩倉 洋一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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