Tsuiji Makoto 築地信

… Alternative Names

TSUIJI Makoto 築地信

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Researcher Number	90302611
Other IDs	https://orcid.org/0000-0002-5607-4880
Affiliation (Current)	2025: 星薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 星薬科大学, 薬学部, 准教授 2015: 星薬科大学, 薬学部, 准教授 2010 – 2013: 星薬科大学, 薬学部, 准教授 2007 – 2008: Tokyo Medical and Dental University, 難治疾患研究所, 特任講師 2003: 東大, 薬学研究科(研究院), 助手 1998 – 2003: Graduate School of Pharmaceutical Sciences, The University of Tokyo, Research Associate, 大学院・薬学系研究科, 助手
Review Section/Research Field	Principal Investigator Environmental pharmacy / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Environmental pharmacy / Biological pharmacy Except Principal Investigator Biological pharmacy / Basic Section 38050:Food sciences-related / Environmental and hygienic pharmacy / Biological pharmacy / Biological Sciences
Keywords	Principal Investigator 免疫記憶 / 可変部 / scFv-Fc / バイオマーカー / レパトア / 抗体 / がん免疫 / 記憶B細胞 / ワクチン / 肺炎球菌 … More / 遺伝子欠損マウス / 催奇形成 / Cタイプレクチン / マクロファージ / アポトーシス / 胎児の発生 / TCR-Fc / scFv / scTCR-Fc / 抗原受容体 / T細胞受容体 / がん病態 / 抗体遺伝子 / T細胞抗原受容体 / がん / 末梢血 / 免疫状態 / 莢膜糖鎖 / 感染症学 / 微生物 / 感染症 / 糖鎖 / 免疫学 / 放射線 / MGL / X線照射 / mMGL … More Except Principal Investigator 細胞接着 / ムチン / MUC2 / PCR / Lectin / マクロファージ / O-グリコシレーション / レクチン / DNAアレイ / 遺伝子発現 / 糖鎖 / 肝転移 / B細胞レパトア / 遺伝 / レパトア / アレルゲン特異性 / B細胞 / アレルギー / マトリックスメタロプロテイナーゼ / MMP / SSL / セレクチン / シアル酸 / 黄色ブドウ球菌 / マトリックス分解酵素 / 細菌分泌タンパク質 / 白血球浸潤 / macrophage / amoeba infection / Ebola virus / O-glycosylation / UDP-GalNAc-polypeptide / Mucin / 生体防御 / グラム陰性菌 / 腸管上皮細胞 / アメーバ赤痢 / エボラウイルス / N-アセチルガラクトサミン転移酵素 / Gene expression / Cancer progression / Expression array / Nude mouse / Micrometastasis / Liver metastasis / Pancreatic carcinoma / 微小転物 / 癌の進行 / DNA アレイ / 膵臓癌 / 微少転移 / がんの進行 / ヌードマウス / 微小転移 / 膵臓がん / Cancer metastasis / Lewis antigen / Macrophage / Cellular trafficking / Cellular recognition / O-glysylation / mucin / O-グリュシレーション / 白血球 / 癌転転 / 癌転移 / ルイス抗原 / 腫瘍免疫 / 細胞交通 / 細胞認識 / 転写因子 / 腫瘍関連マクロファージ / メタロプロテイナーゼ / 腹膜播種 / ラミニン / 腹膜播種転移 / サイトカイン / 細胞外マトリックス / インテグリン / がん浸潤 / 遺伝子診断 / リーリン / RT-PCR / ディファレンシャルディスプレイ / 肝細胞 / colon38細胞 / 生体分子 / ゲノム / 癌 / 遺伝子 / 糖転移酵素 / 遺伝子発現解析 / 足場依存的増殖 / 転移モデル / クラスター解析 / レクチンライブラリー / プロテオミックス / adkn2a / p16ink4a / 遣伝子発現解析 / 足場非依存的増殖 / 細胞周期 / 肝転移モデル Less

Construction of a drug discovery platform utilizing antigen receptors that regulate the quality of cancer immunityPrincipal Investigator
- Principal Investigator
  
  築地信
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Hoshi University
一細胞シークエンスを用いたB細胞レパトア解析によるアレルゲン特異性決定機構の解明
- Principal Investigator
  
  好田正
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Tokyo University of Agriculture and Technology
Repertoirome analysis of antibody genes of peripheral blood memory B cells for qualitative evaluation of tumor associated immune responsePrincipal Investigator
- Principal Investigator
  
  Tsuiji Makoto
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Hoshi University
Suppression of host defense system by bacterial "cell adhesion-perturbing proteins"
- Principal Investigator
  
  Tsuji Tsutomu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  Hoshi University
Modulation by cytokines of integrin-dependent cancer cell adhesion/invasion to peritoneum
- Principal Investigator
  
  TSUJI Tsutomu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hoshi University
Analysis of the mechanism of immunological memory against the capsular polysaccharides of Streptococcus pneumoniaePrincipal Investigator
- Principal Investigator
  
  TSUIJI Makoto
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Hoshi University
Analysis of the molecular mechanisms of immunological memory responses against polysaccharides vaccinesPrincipal Investigator
- Principal Investigator
  
  TSUIJI Makoto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Medical and Dental University
放射線による組織傷害とその後の組織修復への糖鎖認識分子MGL1/2の関与Principal Investigator
- Principal Investigator
  
  築地信
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Environmental pharmacy
- Research Institution
  The University of Tokyo
マウスモデルに基づくヒト大腸癌転移形質のバイオインフォーマティックスによる解析
- Principal Investigator
  
  IRIMURA Tatsuro
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
マクロファージ機能欠損マウスを用いた放射線による催奇形性の研究Principal Investigator
- Principal Investigator
  
  築地信
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Environmental pharmacy
- Research Institution
  The University of Tokyo
Structural diversity of mucins : Significance in infection and immunity
- Principal Investigator
  
  IRIMURA Tatsuro
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
Establishment of hepatic metastasis model of pancreatic carcinoma and it application to the development of therapeutic agents
- Principal Investigator
  
  IRIMURA Tatsuro
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  THE UNIVERSITY OF TOKYO
Regulation of cellular trafficking and pathogenesis by mucins
- Principal Investigator
  
  IRIMURA Tatsuro
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo

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All Journal Article Presentation Book

[Book] 免疫学の基礎　第５版2022
- Author(s)
  入村達郎(監修)，辻勉(編著)，築地信，永井重徳，永田喜三郎，東伸昭，渡辺恵史
- Total Pages
  198
- Publisher
  東京化学同人
- ISBN
  9784807920334
- Data Source
  KAKENHI-PROJECT-22K06603
[Journal Article] Characterization of novel antibodies that recognize sialylated keratan sulfate and lacto-N-fucopentaose I on human induced pluripotent cells: comparison with existing antibodies2023
- Author(s)
  Hiromi Nakao, Tomoko Yamaguchi, Kenji Kawabata, Katsuaki Higashi, Motohiro Nonaka, Makoto Tsuiji, Yuko Nagai, Hidenao Toyoda, Yoshiki Yamaguchi, Nobuko Kawasaki, Toshisuke Kawasaki
- Journal Title
  
  Glycobiology
  
  Volume: 33(2) Issue: 2 Pages: 150-164
- DOI
  10.1093/glycob/cwac074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06603
[Journal Article] rs9459874 and rs1012656 in CCR6/FGFR1OP confer susceptibility to primary biliary cholangitis2022
- Author(s)
  Hitomi Yuki、Aiba Yoshihiro、Ueno Kazuko、Nishida Nao、Kawai Yosuke、Kawashima Minae、Yasunami Michio、Gervais Olivier、Ito Masahiro、Cordell Heather J.、Mells George F.、Nagasaki Masao、Tokunaga Katsushi、Tsuiji Makoto、Nakamura Minoru
- Journal Title
  
  Journal of Autoimmunity
  
  Volume: 126 Pages: 102775-102775
- DOI
  10.1016/j.jaut.2021.102775
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07334, KAKENHI-PROJECT-19K07471, KAKENHI-PROJECT-19K08413, KAKENHI-PROJECT-20K08370
[Journal Article] rs2013278 in the multiple immunological-trait susceptibility locus CD28 regulates the production of non-functional splicing isoforms.2022
- Author(s)
  Yuki Hitomi, Yoshihiro Aiba, Kazuko Ueno, Nao Nishida, Yosuke Kawai, Minae Kawashima, Makoto Tsuiji, Chisato Iwabuchi, Sanami Takada, Noriko Miyake, Masao Nagasaki, Katsushi Tokunaga, Minoru Nakamura
- Journal Title
  
  Human genomics
  
  Volume: 16(1) Issue: 1 Pages: 46-46
- DOI
  10.1186/s40246-022-00419-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06603, KAKENHI-PROJECT-22K08065
[Journal Article] O-Glycan-Dependent Interaction between MUC1 Glycopeptide and MY.1E12 Antibody by NMR, Molecular Dynamics and Docking Simulations2022
- Author(s)
  Kokubu Ryoka、Ohno Shiho、Kuratani Hirohide、Takahashi Yuka、Manabe Noriyoshi、Shimizu Hiroki、Chiba Yasunori、Denda-Nagai Kaori、Tsuiji Makoto、Irimura Tatsuro、Yamaguchi Yoshiki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 14 Pages: 7855-7855
- DOI
  10.3390/ijms23147855
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07163, KAKENHI-PROJECT-22K06562, KAKENHI-PROJECT-22K06603
[Journal Article] rs1944919 on chromosome 11q23.1 and its effector genes COLCA1/COLCA2 confer susceptibility to primary biliary cholangitis2021
- Author(s)
  Hitomi Yuki、Aiba Yoshihiro、Kawai Yosuke、Kojima Kaname、Ueno Kazuko、Nishida Nao、Kawashima Minae、Gervais Olivier、Khor Seik-Soon、Nagasaki Masao、Tokunaga Katsushi、Nakamura Minoru、Tsuiji Makoto
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 4557-4557
- DOI
  10.1038/s41598-021-84042-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07334, KAKENHI-PROJECT-19K08413
[Journal Article] Immunomodulatory Activity of an Aqueous Extract of Mycelium of an Endophytic-Like Fungus, Ustilago esculenta2021
- Author(s)
  Makoto Tsuiji, Junko Nagasaka, Yoshimasa Yajima, Keita Nishiumi, Yasutaka Kojima, Miho Amemiya, Wakana Ogura, Takaaki Moriyama, Tomoko Sakai, Teruaki Oku, Tsutomu Tsuji
- Journal Title
  
  BPB Reports
  
  Volume: 4 (4) Pages: 98-102
- NAID
  130008069606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07334
[Journal Article] A Guillain-Barre syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides2021
- Author(s)
  Alborzian Deh Sheikh Amin、Gomaa Soha、Li Xuexin、Routledge Matthew、Saigoh Kazumasa、Numoto Nobutaka、Angata Takashi、Hitomi Yuki、Takematsu Hiromu、Tsuiji Makoto、Ito Nobutoshi、Kusunoki Susumu、Tsubata Takeshi
- Journal Title
  
  Journal of Autoimmunity
  
  Volume: 116 Pages: 102571-102571
- DOI
  10.1016/j.jaut.2020.102571
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07334, KAKENHI-PUBLICLY-19H04804, KAKENHI-PUBLICLY-20H05349
[Journal Article] Coronin-1 is phosphorylated at Thr-412 by protein kinase Cα in human phagocytic cells2021
- Author(s)
  Oku Teruaki、Kaneko Yutaka、Ishii Rie、Hitomi Yuki、Tsuiji Makoto、Toyoshima Satoshi、Tsuji Tsutomu
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 27 Pages: 101041-101041
- DOI
  10.1016/j.bbrep.2021.101041
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07334, KAKENHI-PROJECT-19K07142
[Journal Article] Reply to Slominski et al.: UVB irradiation induces proenkephalin+ regulatory T cells with a wound-healing function2021
- Author(s)
  Shime Hiroaki、Odanaka Mizuyu、Tsuiji Makoto、Matoba Takuma、Imai Masaki、Yasumizu Yoshiaki、Uraki Ryuta、Minohara Kiyoshi、Watanabe Maiko、Bonito Anthony John、Fukuyama Hidehiro、Ohkura Naganari、Sakaguchi Shimon、Morita Akimichi、Yamazaki Sayuri
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 3
- DOI
  10.1073/pnas.2021919118
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07334, KAKENHI-PROJECT-19K07510, KAKENHI-PROJECT-20K09911, KAKENHI-PROJECT-19KK0202, KAKENHI-PUBLICLY-19H04812, KAKENHI-PROJECT-20H03469, KAKENHI-PROJECT-18K16158
[Journal Article] Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function2020
- Author(s)
  Shime Hiroaki、Odanaka Mizuyu、Tsuiji Makoto、Matoba Takuma、Imai Masaki、Yasumizu Yoshiaki、Uraki Ryuta、Minohara Kiyoshi、Watanabe Maiko、Bonito Anthony John、Fukuyama Hidehiro、Ohkura Naganari、Sakaguchi Shimon、Morita Akimichi、Yamazaki Sayuri
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Issue: 34 Pages: 20696-20705
- DOI
  10.1073/pnas.2000372117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07334, KAKENHI-PROJECT-19K07510, KAKENHI-PROJECT-20K09911, KAKENHI-PROJECT-19K18779, KAKENHI-PROJECT-19KK0202, KAKENHI-PROJECT-16H06295, KAKENHI-PUBLICLY-19H04812, KAKENHI-PROJECT-20H03469, KAKENHI-PROJECT-18K16158, KAKENHI-PROJECT-20H03703, KAKENHI-PROJECT-20K16265, KAKENHI-PROJECT-19K23868
[Journal Article] がん病態関連免疫応答の質的評価のための末梢血記憶B細胞抗体遺伝子レパトローム解析2019
- Author(s)
  築地信
- Journal Title
  
  Precision Medicine
  
  Volume: Vol.2 No.2 Pages: 79-81
- Data Source
  KAKENHI-PROJECT-18K07334
[Journal Article] がん病態関連免疫応答の質的評価のための末梢血記憶B細胞抗体遺伝子レパトローム解析2019
- Author(s)
  築地信
- Journal Title
  
  Medical Science Digest
  
  Volume: Vol.45 No.2 Pages: 14-15
- Data Source
  KAKENHI-PROJECT-18K07334
[Journal Article] Constitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actin.2012
- Author(s)
  Oku T, Nakano M, Kaneko Y, Ando Y, Kenmotsu H, Itoh S, Tsuiji M, Seyama Y, Toyoshima S ,Tsuji T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 287(51) Issue: 51 Pages: 42910-20
- DOI
  10.1074/jbc.m112.349829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590115, KAKENHI-PROJECT-23590092
[Journal Article] Involvement of transcription factor Ets-1 in the expression of the α3 integrin subunit gene.2012
- Author(s)
  Kamoshida G, Matsuda A, Katabami K, Kato T, Mizuno H, Sekine W, Oku T, Itoh S, Tsuiji M, Hattori Y, Maitani Y, Tsuji T.
- Journal Title
  
  FEBS J.
  
  Volume: 279(24) Issue: 24 Pages: 4535-46
- DOI
  10.1111/febs.12040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590115, KAKENHI-PROJECT-23590092, KAKENHI-PROJECT-23790203
[Journal Article] Role of central leptin signaling in the starvation-induced alteration of B cell development2011
- Author(s)
  M. Tanaka, T. Suganami, M. Kim-Saijo, C. Toda, M. Tsuiji, K. Ochi, Y. Kamei, Y. Minokoshi, Y. Ogawa
- Journal Title
  
  J. Neurosci.
  
  Volume: 31 Issue: 23 Pages: 8373-8380
- DOI
  10.1523/jneurosci.6562-10.2011
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21117007, KAKENHI-PROJECT-21390067, KAKENHI-PLANNED-22126005, KAKENHI-PROJECT-22590115
[Journal Article] Distribution and function of macrophage galactose-type C-type lectin 2 (MGL2/CD301b): efficient uptake and presentation of glycosylated antigens by dendritic cells.2010
- Author(s)
  Denda-Nagai K, Aida S, Saba K, Suzuki K, Moriyama S, Oo-Puthinan S, Tsuiji M, Morikawa A, Kumamoto Y, Sugiura D, Kudo A, Akimoto Y, Kawakami H, Bovin NV, Irimura T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285(25) Issue: 25 Pages: 19193-204
- DOI
  10.1074/jbc.m110.113613
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590115, KAKENHI-PROJECT-22590193
[Journal Article] Distribution and function of macrophage galactose-type C-type lectin 2 (MGL2/CD301b) : efficient uptake and presentation of glycosylated antigens by dendritic cells2010
- Author(s)
  Denda-Nagai K, Aida S, Saba K, Suzuki K, Moriyama S, Oo-Puthinan S, Tsuiji M, Morikawa A, Kumamoto Y, Sugiura D, Kudo A, Akimoto Y, Kawakami H, Bovin NV, Irimura T
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 285(25) Pages: 19193-19204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590115
[Journal Article] Autoreactive IgG(+) memory antibodies in patients with systemic erythematosus arise from nonreactive and polyreactive precursors2008
- Author(s)
  Mietzner B, Tsuiji M, Scheid J, Velinzon K, Tiller T, Abraham K, Gonzalez JB, Pascual V, Stichweh D, Wardemann H,and Nussenzweig MC
- Journal Title
  
  Proc Natl AcadSci USA 105
  
  Pages: 9727-9732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599006
[Journal Article] The amino acidsinvolved in the distinct carbohydrate specificities between macrophage galactose-type C-type lectins 1 and 2(CD301a and b)of mice2008
- Author(s)
  Oo-Puthinan S, Maenuma K, Sakakura M, Denda-Nagai K, Tsuiji M, Shimada I, Nakamura-Tsuruta S, Hirabayashi J, BovinNV,and Irimura T
- Journal Title
  
  Biochim Biophys Acta 1780
  
  Pages: 89-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599006
[Journal Article] Identification and expression of human epiglycanin/MUC21 : a novel transmembrane mucin2008
- Author(s)
  Itoh Y, Kamata-Sakurai M, Denda-Nagai K, Nagai S, Tsuiji M, Ishii-Schrade K, Okada K, Goto A, Fukuyama M,and Irimura T
- Journal Title
  
  Glycobiology 18
  
  Pages: 74-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599006
[Journal Article] Efficient generation of monoclonal antibodies from single human B cells bysingle cell RT-PCR and expression vector cloning2008
- Author(s)
  Tiller T, Meffre E, Yurasov S, Tsuiji M, Nussenzweig MC, Wardemann H
- Journal Title
  
  J Immunol Methods 329
  
  Pages: 112-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599006
[Journal Article] The amino acids involved in the distinct carbohydrate specific between macrophage galactose-type C-type lectins 1 and 2 (CD301a and b)of mice.2008
- Author(s)
  Oo-Puthinan S, Maenuma K, Sakakura M, Denda-Nagai K, Tsuiji M, Shimada I, Nakaraura-Tsuruta S, Hirabayashi J, Bovin NV, Irimura T.
- Journal Title
  
  Biochimica et Biophysica Acta 1780(2)
  
  Pages: 89-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599006
[Journal Article] Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning.2008
- Author(s)
  Tiller T, Meffre E, Yurasov S, Tsuiji M, Nussenzweig MC, Wardemann H.
- Journal Title
  
  J Immunol Methods 329(1-2)
  
  Pages: 112-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599006
[Journal Article] Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors.2008
- Author(s)
  Mietzner B, Tsuiji M, Scheid J, Velinzon K, Tiller T, Abraham K, Gonzalez JB, Pascual V, Stichweh D, Wardemann H, Nussenzweig MC.
- Journal Title
  
  Proceedings of the National Academy of Sciences of the U. S. A. 105(28)
  
  Pages: 9727-9732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599006
[Journal Article] Identification and expression of human epiglycanin/MUC21 : a novel transmembrane mucin.2008
- Author(s)
  Itoh Y, Kamata-Sakurai M, Denda-nagai K, Nagai S, Tsuiji M, Ishii-Schrade K, Okada K, Goto A, Fukuyama M, Irimura T.
- Journal Title
  
  Glycobiology 18(1)
  
  Pages: 74-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599006
[Journal Article] Autoreactivity in human IgG(+)memory B cells2007
- Author(s)
  TillerT, Tsuiji M, Yurasov S, Velinzon K, Nussenzweig MC,and Wardemann H
- Journal Title
  
  Immunity 26
  
  Pages: 205-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599006
[Journal Article] Autoreactivity in human IgG+ memory B cells.2007
- Author(s)
  Tiller T, Tsuiji M, Yurasov S, Velinzon K, Nussenzweig MC, Wardemann H.
- Journal Title
  
  Immunity 26(2)
  
  Pages: 205-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599006
[Presentation] SARS-CoV-2に対する抗体の可変部遺伝子レパトア解析2024
- Author(s)
  築地信，森咲也香，白石桃子，大草日向子，藤原伸一
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] ヘパラナーゼ融合タンパク質が結合する分子の解析2024
- Author(s)
  山口アリサ，馬場遼也，荒川颯二郎，中村桃子，高橋勝彦，築地信，中島元夫，入村達郎，東伸昭
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] 9-(E,Z)-Hydroxyoctadecadienoic acid (HODE) によるリンパ腫細胞株EL4およびE.G7-OVAへの効果2024
- Author(s)
  髙石朱莉，平田朱音，築地信
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] 2系統のマウスにおける抗原特異的IgMおよびIgG1発現B細胞の受容体(BCR)レパトア解析2023
- Author(s)
  西原千晶，築地信，服部誠，好田正
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] 塩化ナトリウム高濃度状態がマクロファージ様細胞株RAW264.7細胞に及ぼす影響2023
- Author(s)
  久保田愛梨，佐藤朋広，佐藤淳之介，奥輝明，築地信
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] 抗ヒトTROP2抗体の作製と乳がん細胞株MDA-MB-231に対する細胞傷害活性の解析2023
- Author(s)
  川端里奈，小林莉子，築地信，加藤良規，奥輝明
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] ヒト乳がん細胞MDA-MB-231に対するモノクローナル抗体を用いた細胞傷害活性の解析2023
- Author(s)
  小林莉子，川端里奈，里史明，加藤良規，築地信，奥輝明
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] リンパ腫E.G7-OVA担がんマウスにおける末梢血B細胞とCD4陽性T細胞の抗原受容体レパトローム解析2023
- Author(s)
  築地信，大草日向子，瓜生瑞貴
- Organizer
  日本がん免疫学会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] 2系統のマウスにおける抗原特異的IgMおよびIgG1発現B細胞の受容体(BCR)レパトア解析2023
- Author(s)
  西原千晶、築地信、服部誠、好田正
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-23K23551
[Presentation] Effects of high sodium chloride concentration on the macrophage-like cell line RAW264.7 cells2023
- Author(s)
  Airi Kubota, Junnosuke Sato, Makoto Tsuiji
- Organizer
  JSICR MMCB 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] SARS-CoV-2に対する抗体の可変部遺伝子レパトア解析2023
- Author(s)
  築地信，森咲也香，大草日向子，藤原伸一
- Organizer
  Pharmaco-Hematologyシンポジウム
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] Evaluation of immune response induced by influenza vaccines using the repertoire analysis of variable genes of antibodies2022
- Author(s)
  大草日向子，瓜生瑞貴，藤原伸一，佐藤佳代子，浅沼秀樹，築地信
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] Lacto-N-fucopentaose Iの立体構造および抗iPS細胞抗体R-17Fとの相互作用の解析2022
- Author(s)
  大野詩歩、大内陽翔、齋藤祐希、真鍋法義、湯浅徳行、松崎祐二、築地信、川嵜敏祐、山口芳樹
- Organizer
  日本薬学会年会 142年会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] MUC1糖ペプチドと抗MUC1抗体MY.1E12の相互作用解析2022
- Author(s)
  國府涼香、倉谷太豪、高橋優花、大野詩歩、真鍋法義、清水弘樹、千葉靖典、伝田香里、築地信、入村達郎、山口芳樹
- Organizer
  日本薬学会年会 142年会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] リンパ腫E.G7-OVA担がんマウスにおける末梢血B細胞とCD4陽性T細胞の抗原受容体レパトローム解析2022
- Author(s)
  築地信，大草日向子，瓜生瑞貴
- Organizer
  Pharmaco-Hematologyシンポジウム
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] 腫瘍関連糖鎖抗原を認識する抗体の可変部遺伝子配列の決定と人工抗体の作製2022
- Author(s)
  吉田昌宏、稲垣優希、人見祐基、奥輝明、伝田香里、入村達郎、築地信
- Organizer
  日本薬学会年会 142年会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] Lacto-N-fucopentaose Iの立体構造および抗iPS細胞抗体R-17Fとの相互作用の解析2022
- Author(s)
  大野詩歩，大内陽翔，齋藤祐希，真鍋法義，湯浅徳行，松崎祐二，築地信，川嵜敏祐，山口芳樹
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] 腫瘍関連糖鎖抗原を認識する抗体の可変部遺伝子配列の決定と人工抗体の作製2022
- Author(s)
  吉田昌宏，稲垣優希，人見祐基，奥輝明，伝田香里，入村達郎，築地信
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] 免疫細胞特異的アクチン結合タンパク質Coronin-1の発現制御機構の解析2022
- Author(s)
  安藤祐介，金子豊，長谷川晋也，築地信，渡辺知恵，奥輝明
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] 糖鎖抗原を認識する抗体の可変部遺伝子配列の決定と人工抗体の作製2022
- Author(s)
  築地信、吉田昌宏、稲垣優希、石村彰識、河村桂輔、獅子原弘樹、伝田香里、入村達郎、中尾広美、川嵜敏祐
- Organizer
  第6回糖鎖免疫学研究会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] MUC1糖ペプチドと抗MUC1抗体MY.1E12の相互作用解析2022
- Author(s)
  國府涼香，倉谷太豪，高橋優花，大野詩歩，真鍋法義，清水弘樹，千葉靖典，伝田香里，築地信，入村達郎，山口芳樹
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] 糖鎖抗原を認識する抗体の可変部遺伝子配列の決定と人工抗体の作製2022
- Author(s)
  築地信，吉田昌宏，稲垣優希，石村彰識，河村桂輔，獅子原弘樹，伝田香里，入村達郎，中尾広美，川嵜敏祐
- Organizer
  糖鎖免疫研究会
- Data Source
  KAKENHI-PROJECT-22K06603
[Presentation] 免疫細胞特異的アクチン結合タンパク質Coronin-1の発現制御機構の解析2022
- Author(s)
  安藤祐介、金子豊、長谷川晋也、築地信、渡辺知恵、奥輝明
- Organizer
  日本薬学会年会 142年会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] Proenkephalin+ regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function2021
- Author(s)
  Hiroaki Shime, Mizuyu Odanaka, Makoto Tsuiji, Masaki Imai, Yoshiaki Yasumizu, Ryuta Uraki, Anthony JB, Hidehiro Fukuyama, Naganari Ohkura, Shimon Sakaguchi, Akimichi Morita, Sayuri Yamazaki
- Organizer
  第50回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] Evaluation of immune responses induced by influenza vaccines using antibody repertoire analysis2021
- Author(s)
  Kayoko Sato, Hideki Asanuma, Makoto Tsuiji
- Organizer
  第50回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] 潰瘍性大腸炎モデルマウスの大腸粘膜固有層に集積する細胞へのブシラミンの効果2021
- Author(s)
  柳澤直樹、菊池隼矢、奥輝明、築地信
- Organizer
  第21回 Pharmaco-Hematology シンポジウム
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] NKT-mediated vaccine induces affinity maturation of BCR and supply antibody dependent protection against Streptococcus pneumoniae2021
- Author(s)
  Koji Hayashizaki, Shogo Takatsuka, Yasuhiro Kamii, Makoto Tsuiji, Masato Kubo, Yoshimasa Takahashi, Yuki Kinjo
- Organizer
  第50回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] Identification of the primary functional variants in primary biliary cholangitis susceptibility gene CCR6/FGFR1OP2021
- Author(s)
  Yuki Hitomi, Yoshihiro Aiba, Makoto Tsuiji, Minoru Nakamura
- Organizer
  第50回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] Variable gene repertoirome analysis of peripheral blood BCRs and CD4+ T cell TCRs(alpha/beta) for monitoring of tumor-associated immune responses2021
- Author(s)
  Makoto Tsuiji
- Organizer
  第50回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] Variable gene repertoirome analysis of peripheral blood BCRs and CD4+ T cell TCRs(alpha/beta) for monitoring of tumor-associated immune responses2021
- Author(s)
  Makoto Tsuiji
- Organizer
  2021 JCA-AACR Precision Cancer Medicine International Conference
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] 糖鎖抗原を認識する抗体の可変部遺伝子配列の決定と人工抗体の作製2021
- Author(s)
  築地信、吉田昌宏、稲垣優希、石村彰識、河村桂輔、獅子原弘樹、伝田香里、入村達郎、中尾広美、川嵜敏祐
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] Skin regulatory T cells expanded by ultraviolet B exposure have a unique gene expression profile compared to other tissue Treg cells2021
- Author(s)
  Mizuyu Odanaka, Hiroaki Shime, Makoto Tsuiji, Masaki Imai, Yoshiaki Yasumizu, Ryuta Uraki, Anthony JB, Hidehiro Fukuyama, Naganari Ohkura, Shimon Sakaguchi, Akimichi Morita, Sayuri Yamazaki
- Organizer
  第50回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] 腫瘍関連抗原を認識する抗体の可変部遺伝子配列の決定と人工抗体の作製2020
- Author(s)
  築地信, 澁澤晴美, 岡部早希子, 林美佑, 稲垣優希, 吉田昌宏, 人見祐基, 奥輝明, 伝田香里, 入村達郎
- Organizer
  日本薬学会年会140th
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] ヒト由来細胞を利用した新規発熱性物質試験法の開発2020
- Author(s)
  奥輝明, 安藤祐介, 人見祐基, 築地信, 亀井淳三, 林克彦, 菊池裕, 菊池裕, 工藤由起子, 伊豆津健一, 辻勉
- Organizer
  日本薬学会年会140th
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] 糖鎖認識抗体によるエピトープ認識の分子基盤2020
- Author(s)
  川嵜敏祐, 中尾広美, 川嵜伸子, 築地信, 稲垣優希, 吉田昌宏, 山口芳樹, 天野裕之, 大野詩歩, 真鍋法義
- Organizer
  日本生化学会大会93rd
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] 担がんマウスにおける免疫状態を評価するための末梢血B細胞およびT細胞の抗原受容体遺伝子レパトローム解析2019
- Author(s)
  築地信、岡部早希子、澁澤晴美、林美佑
- Organizer
  第92回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] Variable gene repertoirome analysis of peripheral blood BCRs and CD4+ T cell TCRs(alpha/beta) for monitoring of cancer-associated immune responses2019
- Author(s)
  Makoto Tsuiji
- Organizer
  第48回　日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] Variable gene repertoirome analysis of peripheral blood BCRs and CD4+ TCRs (a/b) for qualitative evaluation of cancer-associated immune response2018
- Author(s)
  M. Tsuiji, S. Okabe, H. Shibusawa, T. Yamaguchi, Y. Hayakawa, T. Tsuji
- Organizer
  第47回　日本免疫学学術集会
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] Antibody gene repertoirome analysis of peripheral blood B cells for quantitative evaluation of cancer-associated immune response2018
- Author(s)
  M. Tsuiji, S. Okabe, H. Shibusawa, T. Yamaguchi, Y. Hayakawa, T. Tsuji
- Organizer
  The 6th JCA-AACR Special Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] 担がんマウスにおける末梢血B細胞の抗体遺伝子レパトローム解析2018
- Author(s)
  築地信、岡部早希子、澁澤晴美、山口大樹、早川侑希、辻勉
- Organizer
  第19回　Pharmaco-Hematologyシンポジウム
- Data Source
  KAKENHI-PROJECT-18K07334
[Presentation] 免疫細胞活性化マーカーCD83 のリガンド探索2012
- Author(s)
  安藤祐介,栗坂知里,奥輝明,築地信,辻勉.
- Organizer
  第35回日本分子生物学会年会
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-22590115
[Presentation] 末梢血記憶B細胞抗体遺伝子レパトローム解析2012
- Author(s)
  築地信、安藤祐介、鍔田武志、Michel C. Nussenzweig、辻勉
- Organizer
  第１３回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590115
[Presentation] 免疫細胞活性化マーカーCD83のリガンド探索2012
- Author(s)
  安藤祐介、栗坂知里、奥輝明、築地信、辻勉
- Organizer
  第３５回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590115
[Presentation] Analysis of the immune resonse against capsular polysaccharides of Streptococcus pneumoniae and the ligands of CD83, a candidate for sugar-recognizing molecule.2012
- Author(s)
  Tsuiji M, Ando Y, Tanaka M, Imai N, Hayashizaki K, Kurisaka C, Oku T, Tsubata T, Tsuji T.
- Organizer
  International Symposium on Glyco-minded Biology of Diseases as a Basis of Pharmaceutical Sciences
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-22590115
[Presentation] 鍔田武志,Michel C. Nussenzweig,辻勉. 末梢血記憶 B 細胞抗体遺伝子レパトローム解析2012
- Author(s)
  築地信,安藤祐介
- Organizer
  第13回Pharmaco-Hematology シンポジウム
- Year and Date
  2012-06-15
- Data Source
  KAKENHI-PROJECT-22590115
[Presentation] Potentiation of gastric carcinoma cell invasion by TNF-αand MMP secretion from peritoneal mesothelial2012
- Author(s)
  Tsuji, T, Shimada K, Kenmotsu, H, Sekine, W, Saito, Y, Oku, T, Tsuiji, M
- Organizer
  Experimental Biology 2012
- Place of Presentation
  San Diego,米国
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] 腹膜中皮細胞単層培養系を用いた胃がん細胞の浸潤能の評価と炎症性サイトカインの作用2012
- Author(s)
  劍持宏樹,島田賢太郎,奥輝明,築地信,辻勉
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] 腹膜中皮細胞単層培養系を用いた胃がん細胞の浸潤能の評価とサイトカインの作用2012
- Author(s)
  劍持宏樹、島田賢太郎、奥　輝明、築地　信、辻　　勉
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590092
[Presentation] Analysis of the immune response against capsular polysaccharides of Streptococcus pneumonia and the ligands of CD83, a candidate for sugar-recognizing molecule2012
- Author(s)
  Tsuiji M, Ando Y, Tanaka M, Imai N, Hayashizaki K, Kurisaka C, Oku T, Tsubata T, Tsuji T.
- Organizer
  International Symposium on Glyco-minded Biology of Diseases as a Basis of Pharmaceutical Sciences
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-22590115
[Presentation] The immune response during the primary phase against capsular polys accharides of Streptococcus pneumoniae.2010
- Author(s)
  Tsuiji M, Tanaka M, Imai N, Hayashizaki K, Tsubata T.
- Organizer
  The 28th Naito conference on Glycan Expression and Regulation [1]
- Place of Presentation
  Shonan Village Center, Kanagawa, Japan
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-22590115
[Presentation] The immune response during the primary phase against capsular polysaccharides of Streptococcus pneumoniae.2010
- Author(s)
  Tsuiji M, Tanaka M, Imai N, Hayashizaki K, Tsubata T.
- Organizer
  The 28^<th> Naito conference on Glycan Expression and Regulation
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-22590115
[Presentation] The immune response during the primary phase against capsular polys accharides of Streptococcus pneumoniae.2010
- Author(s)
  Tanaka M, Imai N, Tsubata T, Tsuiji M
- Organizer
  14th International congress of Immunology
- Place of Presentation
  Kobe Convention Center, Kobe, Japan
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-22590115
[Presentation] The immune response during the primary phase against capsular polysaccharides of Streptococcus pneumoniae.2010
- Author(s)
  Tanaka M, Imai N ,Tsubata T, Tsuiji M.
- Organizer
  14^<th> International congress of Immunology, Aug. 25^<th>
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-22590115
[Presentation] Autoreactivity in human IgG+ memory B cells2007
- Author(s)
  Tiller T, Tsuiji M, Yurasov S, Velinzon K, Nussenzweig MC and Wardemann H
- Organizer
  Keystone symposia, Biology of Bcells in Health and Disease
- Place of Presentation
  (ポスター発表)
- Year and Date
  2007-02-10
- Data Source
  KAKENHI-PROJECT-19599006
[Presentation] IgG plasmablast and memory B cell antibodiesin patients with SLE.Keystone symposia2007
- Author(s)
  Tsuiji M, Mietzner B, Scheid J, Feraoun N, Yurasov S, Velinzon K, Wardemann H and Nussenzweig MC
- Organizer
  Biology of B cells in Health and Disease
- Place of Presentation
  (ポスター発表)
- Year and Date
  2007-02-09
- Data Source
  KAKENHI-PROJECT-19599006

1. IRIMURA Tatsuro (80092146)

# of Collaborated Projects: 4 results

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2. HIGASHI Nubuaki (40302616)

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3. TSUJI Tsutomu (00143503)

# of Collaborated Projects: 3 results

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4. NAGAI-DENDA Kaori (00313122)

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5. OKU Teruaki (20409361)

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# of Collaborated Products: 3 results
6. YAMAMOTO Kazuo (20174782)

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7. BEPPU Tomoe (00111542)

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8. 今井康之 (80160034)

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9. 好田正 (20302911)

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10. 服部誠 (40221501)

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11. 傅田香里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 小川佳宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsuiji Makoto 築地 信

TSUIJI Makoto 築地 信

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Construction of a drug discovery platform utilizing antigen receptors that regulate the quality of cancer immunityPrincipal Investigator

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一細胞シークエンスを用いたB細胞レパトア解析によるアレルゲン特異性決定機構の解明

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Repertoirome analysis of antibody genes of peripheral blood memory B cells for qualitative evaluation of tumor associated immune responsePrincipal Investigator

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Suppression of host defense system by bacterial "cell adhesion-perturbing proteins"

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Modulation by cytokines of integrin-dependent cancer cell adhesion/invasion to peritoneum

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Analysis of the mechanism of immunological memory against the capsular polysaccharides of Streptococcus pneumoniaePrincipal Investigator

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Analysis of the molecular mechanisms of immunological memory responses against polysaccharides vaccinesPrincipal Investigator

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放射線による組織傷害とその後の組織修復への糖鎖認識分子MGL1/2の関与Principal Investigator

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マウスモデルに基づくヒト大腸癌転移形質のバイオインフォーマティックスによる解析

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マクロファージ機能欠損マウスを用いた放射線による催奇形性の研究Principal Investigator

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Structural diversity of mucins : Significance in infection and immunity

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Establishment of hepatic metastasis model of pancreatic carcinoma and it application to the development of therapeutic agents

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Regulation of cellular trafficking and pathogenesis by mucins

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Tsuiji Makoto 築地信

TSUIJI Makoto 築地信

[Book] 免疫学の基礎　第５版2022