HOSOYA Osamu 細谷修

… Alternative Names

細谷修ホソヤオサム

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Researcher Number	90304310
Other IDs
Affiliation (Current)	2025: 岡山大学, 医歯薬学域, 助教
Affiliation (based on the past Project Information) *help	2021 – 2023: 岡山大学, 医歯薬学域, 助教 2013: 岡山大学, 大学院・医歯薬学総合研究科, 助教 2012 – 2013: 岡山大学, 医歯(薬)学総合研究科, 助教 2011: 岡山大学, 大学院・医歯薬学総合研究科, 助教 2007 – 2008: Okayama University, 大学院・医歯薬学総合研究科, 助教 2005: 岡山大学, 大学院医歯薬学総合研究科, 助手 2001 – 2004: 岡山大学, 大学院・医歯学総合研究科, 助手
Review Section/Research Field	Principal Investigator Ophthalmology / Basic Section 56060:Ophthalmology-related / General anatomy (including Histology/Embryology) Except Principal Investigator Genome biology / Ophthalmology
Keywords	Principal Investigator 網膜 / amphiphysin I / スプライスバリアント / エンドサイトーシス / ribbon synapse / retina / endocytosis / 網膜変性疾患 / 網膜疾患 / Cre/loxP … More / CRISPR/Cas9 / Tet-ON / メダカ / 視細胞 / トポイソメラーゼIIβ / actin cytoskeleton / immunoprecipitation / immunohistochemistry / splice variant / アクチン細胞骨格 / 免疫沈降法 / 免疫組織化学 / リボンシナプス / スプライスバイアント / 膜小胞輸送 / アンフィファイジン / 色素上皮細胞 / 膜輸送と輸送タンパク質 / エンドソーム / 生体膜 / 網膜色素上皮細胞 / 眼細胞生物学 / 眼生化学・分子生物学 / retinal pigment epithelium / RNAi … More Except Principal Investigator 分化 / 発生 / 発生・分化 / 発現制御 / 酵素 / ゲノム / 遺伝子 / immunoelectron microscopy / partner protein / heterocomplex / endocytosis / ribbon synapse / retina / variant / amphiphysin Less

網膜視細胞におけるトポイソメラーゼIIβの生理、病理学的役割の検証Principal Investigator
- Principal Investigator
  
  細谷修
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Okayama University
Roles of type II DNA topoisomerase in the interaction of distant genomic sites
- Principal Investigator
  
  TSUTSUI KEN
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genome biology
- Research Institution
  Okayama University
Studies on the function of amphiphysin Ir in retinal pigment epitheliumPrincipal Investigator
- Principal Investigator
  
  HOSOYA Osamu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Okayama University
誘導型RNAi法の開発とこれを用いた網膜リボンシナプス情報伝達の分子機構の解明Principal Investigator
- Principal Investigator
  
  細谷修
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Okayama University
網膜リボンシナプスにおける視覚情報伝達の分子メカニズムの研究
- Principal Investigator
  
  TSUTSUI Kimiko
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Okayama University
Immunohistochemical Study on the Localization of Amphiphysin Ir, Novel Retina-Specific Variants of Amphiphysin I, in the Rat RetinaPrincipal Investigator
- Principal Investigator
  
  HOSOYA Osamu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Okayama University

All 2021 2014 2013 2012 2011 2009 2007 2004

All Journal Article Presentation

[Journal Article] A modified Tet-ON system minimizing leaky expression for cell-type specific gene induction in medaka fish2021
- Author(s)
  Hosoya O, Chung M, Ansai S, Takeuchi H*, Miyaji M*
- Journal Title
  
  Dev Growth Differ
  
  Volume: 63 Issue: 8 Pages: 397-405
- DOI
  10.1111/dgd.12743
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04925, KAKENHI-PROJECT-21K06122, KAKENHI-PROJECT-21K09721
[Journal Article] The CENP-O complex requirement varies among different cell types.2014
- Author(s)
  Kagawa, N., Hori, T., Hoki, Y., Hosoya, O., Tsutsui, K., Saga, Y., Sado, T., and *Fukagawa, T.
- Journal Title
  
  Chrom. Research
  
  Volume: in press Issue: 3 Pages: 293-303
- DOI
  10.1007/s10577-014-9404-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115005, KAKENHI-PROJECT-23310133, KAKENHI-PLANNED-25116002, KAKENHI-PROJECT-25221106, KAKENHI-PROJECT-25287099, KAKENHI-PROJECT-25291078, KAKENHI-PUBLICLY-26114715, KAKENHI-PROJECT-26440190
[Journal Article] Behavior tests and immunohistochemical retinal response analyses in RCS rats with subretinal implantation of Okayama-University-type retinal prosthesis2013
- Author(s)
  Alamusi, Matsuo T., Hosoya O., Tsutsui K.M., Uchida T
- Journal Title
  
  Journal of Artificial Organs
  
  Volume: 16 Issue: 3 Pages: 343-351
- DOI
  10.1007/s10047-013-0697-1
- NAID
  120005526620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310133
[Journal Article] Nuclear protein LEDGF/p75 recognizes supercoiled DNA by a novel DNA-binding domain2011
- Author(s)
  Tsutsui, K.M., Sano, K., Hosoya, O., Miyamoto, T., Tsutsui, K
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 39 (12) Pages: 5067-5081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310133
[Journal Article] 網膜リボンシナプスの情報伝達と網膜特異的Amphiphysin Irの機能2009
- Author(s)
  筒井公子、細谷修
- Journal Title
  
  Acta Anatomic Nipponica 84
  
  Pages: 86-86
- Data Source
  KAKENHI-PROJECT-19791268
[Journal Article] 人工網膜からみた網膜神経細胞の機能2009
- Author(s)
  松尾俊彦、内田哲也、財部健一、細谷修、筒井公子
- Journal Title
  
  Acta Anatomic Nipponica 84
  
  Pages: 87-87
- Data Source
  KAKENHI-PROJECT-19791268
[Journal Article] Amphiphysin Ir participates in receptor-mediated endocytosis in ARP-192007
- Author(s)
  Osamu Hosoya
- Journal Title
  
  Neuroscience Research 58/S1
  
  Pages: 95-95
- Data Source
  KAKENHI-PROJECT-19791268
[Journal Article] Amphiphysin Ir participates in receptor-mediated endocytosis in ARPE-192007
- Author(s)
  Osamu Hosoya, Kimiko M Tsutsui, Ken Tsutsui
- Journal Title
  
  Neuroscience Research 58/S1
- Data Source
  KAKENHI-PROJECT-19791268
[Journal Article] Molecular mechanism of endocytosis following tonic neurotransmitter release in the retinal ribbon synapses.2004
- Author(s)
  Kimiko Tsutsui Osamu Hosoya, Kuniaki Sano, Ken Tsutsui
- Journal Title
  
  International Symposium on Nano-Biotechnology & 6^<th> International Conference on Protein Phosphatases
  
  Pages: 60-60
- Data Source
  KAKENHI-PROJECT-16791048
[Journal Article] Localized expression of amphiphysin Ir, a retina-specific variant of amphiphysin I, in the ribbon synapse and its functional implication.2004
- Author(s)
  Osamu Hosoya, Ken Tsutsui, Kimiko Tsutsui
- Journal Title
  
  European Journal of Neuroscience 19
  
  Pages: 2179-2187
- Data Source
  KAKENHI-PROJECT-16791048
[Journal Article] Binding pertners of the retina-specific amphiphysin I variants imply its role in the endocytic process unique to ribbon synapses.2004
- Author(s)
  Osamu Hosoya, Shinji Kawano, Ken Tsutsui, Kimiko Tsutsui
- Journal Title
  
  生化学 76・8
  
  Pages: 941-941
- Data Source
  KAKENHI-PROJECT-16791048
[Presentation] メダカDNAトポイソメラーゼIIβによる神経系の遺伝子発現制御2021
- Author(s)
  宮地まり, 河野慎二, 細谷修, 竹内秀明, 筒井公子, 筒井研
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K09721
[Presentation] 改良型Tet-ONシステムを用いたメダカ網膜特異的な遺伝子発現誘導2021
- Author(s)
  細谷修, Myung Chung, 安齋賢, 竹内秀明, 宮地まり
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K09721
[Presentation] II型DNAトポイソメラーゼによる神経特異的遺伝子の発現制御機構2013
- Author(s)
  宮地まり、佐野訓明、古田良平、細谷　修、筒井公子、筒井　研
- Organizer
  第12回　細胞核ダイナミクス研究会
- Place of Presentation
  ホテルおかだ（神奈川県足柄下郡箱根町）
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] DNAトポイソメラーゼIIβによる遺伝子制御と核構造2013
- Author(s)
  古田良平、宮地まり、佐野訓明、細谷　修、筒井公子、筒井　研
- Organizer
  第36回　日本分子生物学会
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] II型トポイソメラーゼによる核内構造変化と遺伝子発現制御2012
- Author(s)
  宮地まり、古田良平、佐野訓明、細谷　修、筒井公子、筒井　研
- Organizer
  第30回　染色体ワークショップ・第11回　細胞核ダイナミクス研究会
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] DNAトポイソメラーゼIIβはC末端領域にある新規ドメインを介してRNAにより制御されている2012
- Author(s)
  小野田彰久、木山和子、細谷修、佐野訓明、筒井研、筒井公子
- Organizer
  第35回　日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡(福岡県)
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] 網膜視細胞の終末分化におけるDNAトポイソメラーゼIIβの役割2011
- Author(s)
  細谷修
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] Amphiphysin Ir participates in receptor-mediated endocytosis in ARPE-192007
- Author(s)
  Osamu Hosoya et al.
- Organizer
  Neuro2007
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-19791268
[Presentation] Amphiphysin Ir participates in receptor-mediated endocytosis in ARP-192007
- Author(s)
  Osamu Hosoya
- Organizer
  Neuro2007
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19791268

1. TSUTSUI Kimiko (70144748)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
2. TSUTSUI Ken (70108158)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. MIYAJI Mary (50349255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SANO Kuniaki (00294405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. KUWANO Ryozo (20111734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山口まり

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. 佐渡敬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 竹内秀明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HOSOYA Osamu 細谷 修

細谷 修 ホソヤ オサム

Research Projects

Research Products

Co-Researchers

網膜視細胞におけるトポイソメラーゼIIβの生理、病理学的役割の検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of type II DNA topoisomerase in the interaction of distant genomic sites

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the function of amphiphysin Ir in retinal pigment epitheliumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

誘導型RNAi法の開発とこれを用いた網膜リボンシナプス情報伝達の分子機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

網膜リボンシナプスにおける視覚情報伝達の分子メカニズムの研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunohistochemical Study on the Localization of Amphiphysin Ir, Novel Retina-Specific Variants of Amphiphysin I, in the Rat RetinaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A modified Tet-ON system minimizing leaky expression for cell-type specific gene induction in medaka fish2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The CENP-O complex requirement varies among different cell types.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Behavior tests and immunohistochemical retinal response analyses in RCS rats with subretinal implantation of Okayama-University-type retinal prosthesis2013

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Nuclear protein LEDGF/p75 recognizes supercoiled DNA by a novel DNA-binding domain2011

Author(s)

Journal Title

Data Source

[Journal Article] 網膜リボンシナプスの情報伝達と網膜特異的Amphiphysin Irの機能2009

Author(s)

Journal Title

Data Source

[Journal Article] 人工網膜からみた網膜神経細胞の機能2009

Author(s)

Journal Title

Data Source

[Journal Article] Amphiphysin Ir participates in receptor-mediated endocytosis in ARP-192007

Author(s)

Journal Title

Data Source

[Journal Article] Amphiphysin Ir participates in receptor-mediated endocytosis in ARPE-192007

Author(s)

Journal Title

Data Source

[Journal Article] Molecular mechanism of endocytosis following tonic neurotransmitter release in the retinal ribbon synapses.2004

Author(s)

Journal Title

HOSOYA Osamu 細谷修

細谷修ホソヤオサム