KOBAYASHI Takehiro 小林武弘

Researcher Number	90311670
Affiliation (based on the past Project Information) *help	2009 – 2011: Niigata University, 医歯学系, 准教授 2008: Niigata University, 医歯学系, 講師 2005 – 2006: 新潟大学, 医歯学系, 講師 2004: 新潟大学, 大学院・医歯学総合研究科, 講師 2002: university medical hospital, Assistant, 医学部附属病院, 助手 1999 – 2001: 新潟大学, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Pediatrics / Pediatrics Except Principal Investigator Pediatrics
Keywords	Principal Investigator Ahal / アルポート症候群 / actin filament / binding protein / podocin / podocyte / 腎臓 / アクチン線維 / 結合蛋白 / ポドシン … More / 糸球体上皮細胞 / トランスジェニックマウス / モデルマウス / IV型コラーゲンα5鎖 / IV型コラーゲンα鎖 / NClドメイン / 変異 / コラーゲンドメイン / NC1ドメイン / HSP47 / ヘテロ三量体 / IV型コラーゲン / 脳皮質異形成 / てんかん … More Except Principal Investigator cloning / leukemia / gene / cell line / drug resistance / クローニング / 白血病 / 遺伝子 / 細胞株 / 薬剤耐性 Less

アルポート症候群新規モデルマウスの作出と新たな分子病態の実証および治療法の開発Principal Investigator
- Principal Investigator
  
  小林武弘
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
Basic study for molecular mechanisms and novel therapy of Alport syndromePrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Takehiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
Identification and functional analysis of a novel podocyte-related proteinPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Takehiro
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University
Sequencing and functional analysis of a gene increasedly expressed in drug-resistant leukemia.
- Principal Investigator
  
  KAKIHARA Toshio
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  NIIGATA UNIVERSITY
脳皮質異形成で発現が特異的に変化している遺伝子の同定とその機能解析Principal Investigator
- Principal Investigator
  
  小林武弘
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pediatrics
- Research Institution
  Niigata University

All 2010 2009 2008

All Journal Article Presentation

[Journal Article] 遺伝性腎炎の分子病態2010
- Author(s)
  小林武弘
- Journal Title
  
  新潟医学会雑誌
  
  Volume: 124 Pages: 301-306
- NAID
  120006747937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591273
[Journal Article] Mutant-type α5(IV)collagen in a mild form of Alport syndrome has residual ability to form a heterotrimer.2010
- Author(s)
  Kobayashi T, Uchiyama M.
- Journal Title
  
  Pediatric Nephrology 25
  
  Pages: 1169-1172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591273
[Journal Article] Effect of HSP47 expression levels on heterotrimer formation among type IV collagen α3, α4 and α5 chains.2010
- Author(s)
  小林武弘
- Journal Title
  
  Biomedical Research
  
  Volume: 31 Pages: 371-377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591273
[Journal Article] 遺伝性腎炎の分子病態2010
- Author(s)
  小林武弘
- Journal Title
  
  新潟医学会雑誌 124(In press)
- NAID
  120006747937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591273
[Journal Article] 遺伝性腎炎の分子病態.2010
- Author(s)
  小林武弘.
- Journal Title
  
  新潟医学会雑誌 124
  
  Pages: 301-306
- NAID
  120006747937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591273
[Journal Article] Mutant-type α5(IV) collagen in a mild form of Alport syndrome has residual ability to form a heterotrimer2010
- Author(s)
  小林武弘
- Journal Title
  
  Pediatric Nephrology 25
  
  Pages: 1169-1172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591273
[Journal Article] Effect of HSP47 expression levels on heterotrimer formation among type IV collagen α3, α4 and α5 chains.2010
- Author(s)
  Kobayashi T, Uchiyama M.
- Journal Title
  
  Biomedical Research 31
  
  Pages: 371-377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591273
[Journal Article] Abnormal expression of collagen IV in lens activates the unfolded protein response resulting in cataract.2009
- Author(s)
  Firtina Z, Danysh BP, Bai X, Gould DB, Kobayashi T, Duncan MK.
- Journal Title
  
  Jounal of Biological Chemistry 284
  
  Pages: 35872-35884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591273
[Journal Article] Mutational analysis of type IV collagen α5 chain, with respect to heterotrimer formation.2008
- Author(s)
  Kobayashi T, Kakihara T, Uchiyama M.
- Journal Title
  
  Biochemical and Biophysical Research Communications 366
  
  Pages: 60-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591273
[Presentation] C1638Y変異を有するIV型コラーゲンα5鎖のα3鎖、α4鎖との複合体形成に関する解析2009
- Author(s)
  小林武弘
- Organizer
  第112回日本小児科学会学術集会
- Place of Presentation
  奈良市奈良県中小企業会館
- Year and Date
  2009-04-18
- Data Source
  KAKENHI-PROJECT-20591273
[Presentation] C1638Y変異を有するIV型コラーゲンα5鎖のα3、α4鎖との複合体形成に関する解析.2009
- Author(s)
  小林武弘
- Organizer
  第112回日本小児科学会学術集会.
- Place of Presentation
  奈良市
- Year and Date
  2009-04-18
- Data Source
  KAKENHI-PROJECT-20591273
[Presentation] 遺伝性腎炎の分子病態.2009
- Author(s)
  小林武弘
- Organizer
  第651回新潟医学会例会.
- Place of Presentation
  新潟市
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-20591273

1. IKEZUMI Yohei (70361897)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. UCHIYAMA Makoto (80108050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. KAKIHARA Toshio (70262433)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KANEKO Utako (20401747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOBAYASHI Takehiro 小林 武弘

Research Projects

Research Products

Co-Researchers

アルポート症候群新規モデルマウスの作出と新たな分子病態の実証および治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic study for molecular mechanisms and novel therapy of Alport syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and functional analysis of a novel podocyte-related proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Sequencing and functional analysis of a gene increasedly expressed in drug-resistant leukemia.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脳皮質異形成で発現が特異的に変化している遺伝子の同定とその機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 遺伝性腎炎の分子病態2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Mutant-type α5(IV)collagen in a mild form of Alport syndrome has residual ability to form a heterotrimer.2010

Author(s)

Journal Title

Data Source

[Journal Article] Effect of HSP47 expression levels on heterotrimer formation among type IV collagen α3, α4 and α5 chains.2010

Author(s)

Journal Title

Data Source

[Journal Article] 遺伝性腎炎の分子病態2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 遺伝性腎炎の分子病態.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Mutant-type α5(IV) collagen in a mild form of Alport syndrome has residual ability to form a heterotrimer2010

Author(s)

Journal Title

Data Source

[Journal Article] Effect of HSP47 expression levels on heterotrimer formation among type IV collagen α3, α4 and α5 chains.2010

Author(s)

Journal Title

Data Source

[Journal Article] Abnormal expression of collagen IV in lens activates the unfolded protein response resulting in cataract.2009

Author(s)

Journal Title

Data Source

[Journal Article] Mutational analysis of type IV collagen α5 chain, with respect to heterotrimer formation.2008

Author(s)

Journal Title

Data Source

[Presentation] C1638Y変異を有するIV型コラーゲンα5鎖のα3鎖、α4鎖との複合体形成に関する解析2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] C1638Y変異を有するIV型コラーゲンα5鎖のα3、α4鎖との複合体形成に関する解析.2009

KOBAYASHI Takehiro 小林武弘