Miyamoto Hiroyuki 宮本浩行

… Alternative Names

MIYAMOTO Hiroyuki 宮本浩行

宮本浩行ミヤモトヒロユキ

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Researcher Number	90312280
Other IDs
Affiliation (Current)	2025: 東京大学, ニューロインテリジェンス国際研究機構, 特任准教授
Affiliation (based on the past Project Information) *help	2025: 東京大学, ニューロインテリジェンス国際研究機構, 特任准教授 2020 – 2023: 東京大学, ニューロインテリジェンス国際研究機構, 特任准教授 2018 – 2019: 東京大学, ニューロインテリジェンス国際研究機構, 特任講師 2015 – 2017: 国立研究開発法人理化学研究所, 脳科学総合研究センター, 研究員 2013 – 2014: 独立行政法人理化学研究所, 脳科学総合研究センター, 研究員 … More 2012: 独立行政法人理化学研究所, シナプス分子機構研究チーム, 客員研究員 2010: The Institute of Physical and Chemical Research, シナプス分子機構研究チーム, 客員研究員 2008 – 2009: The Institute of Physical and Chemical Research, 神経回路発達研究チーム, 研究員 2005 – 2006: 独立行政法人理化学研究所, 神経回路発達研究チーム, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 46030:Function of nervous system-related / Neurophysiology and muscle physiology / Basic Section 52030:Psychiatry-related / Psychiatric science / 睡眠科学
Keywords	Principal Investigator NMDA受容体 / 睡眠・覚醒 / Stxbp1 / Munc18-1 / 攻撃性 / てんかん / シナプス伝達 / 神経活動 / 可塑性 / 視覚 … More / 睡眠 / 塩素イオンセンサー / GABA抑制系 / 脳発達 / 臨界期 / 興奮性伝達 / Ｓｔｘｂｐ１ / ｓｔｘｂｐ１ / 皮質－線条体 / 皮質－線条体経路 / 興奮性シナプス伝達 / 発達障害 / 皮質ー線条体 / 欠神てんかん / Scn2a / 大脳基底核 / Ampakine / 大田原症候群 / intellectual disability / ampakine / MUNC18-1 / STXBP1 / Local Field Potential / 睡眠障害 / 前納基底部・視索前野 / セロトニン系 / 前脳基底部・視索前野 / 視交叉上核 / セロトニン / サーカディアンリズム / マルチユニット活動 / 行動マウス / 大脳皮質 / 視覚系 / マルチニューロン活動 / 抑制系 / 単シナプス結合 / 機能的結合 / マルチニューロン記録 / シナプス可塑性 / 知覚学習 / テトロード / 無麻酔慢性記録 / ディアゼパム / マルチユニット記録 / 抑制性ニューロン / 眼優位可塑性 / マウス視覚野 Less

腸内細菌は脳の老廃物排泄機構グリンパティックシステムにどのように影響しているかPrincipal Investigator
- Principal Investigator
  
  宮本浩行
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  The University of Tokyo
発達期レム睡眠が育てるノンレム睡眠の成熟＝マウス臨界期操作によるアプローチ＝Principal Investigator
- Principal Investigator
  
  宮本浩行
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  The University of Tokyo
Identification of the brain regions responsible for epilepsy and aggression induced by impaired synaptic transmissionPrincipal Investigator
- Principal Investigator
  
  Miyamoto Hiroyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  The University of Tokyo
Circuit mechanisms for intractable epilepsy and intellectual disabilities caused by impairments of synaptic transmissionPrincipal Investigator
- Principal Investigator
  
  Miyamoto Hiroyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Institute of Physical and Chemical Research
Serotonergic integration of circadian clock and ultradian sleep-wake cyclesPrincipal Investigator
- Principal Investigator
  
  MIYAMOTO Hiroyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  睡眠科学
- Research Institution
  The Institute of Physical and Chemical Research
State-dependent intracortical connectivity in the mouse visual cortexPrincipal Investigator
- Principal Investigator
  
  MIYAMOTO Hiroyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  The Institute of Physical and Chemical Research
視覚経験依存的な神経回路の再構成における睡眠の働きPrincipal Investigator
- Principal Investigator
  
  宮本浩行
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  The Institute of Physical and Chemical Research

[Book] 視能訓練学2018
- Author(s)
  公益社団法人日本視能訓練士協会(編) ヘンシュ貴雄・宮本浩行（分担執筆）
- Total Pages
  440
- Publisher
  医学書院
- ISBN
  9784260032230
- Data Source
  KAKENHI-PROJECT-15K09848
[Book] 睡眠科学2016
- Author(s)
  宮本浩行・ヘンシュ孝雄
- Total Pages
  344
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-15K09848
[Book] 実験医学　脳神経回路リモデリング2015
- Author(s)
  ヘンシュ貴雄・宮本浩行
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15K09848
[Journal Article] Criticality supports cross-frequency cortical-thalamic information transfer during conscious states2024
- Author(s)
  Toker D, Muller E, Miyamoto H, Riga MS, Llado-Pelfort L, Yamakawa K, Artigas F, Shine JM, Hudson AE, Pouratian N, Monti MM
- Journal Title
  
  eLife
  
  Volume: 13
- DOI
  10.7554/elife.86547
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06436
[Journal Article] CUX2 deficiency causes facilitation of excitatory synaptic transmission onto hippocampus and increased seizure susceptibility to kainate2022
- Author(s)
  Suzuki T, Tatsukawa T, Sudo G, Delandre C, Pai YJ, Miyamoto H, Raveau M, Shimohata A, Ohmori I, Hamano S, Haginoya K, Uematsu M, Takahashi Y, Morimoto M, Fujimoto S, Osaka H, Oguni H, Osawa M, Ishii A, Hirose S, Kaneko S, Inoue Y, Moore AW, Yamakawa K.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 6505-6505
- DOI
  10.1038/s41598-022-10715-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06436, KAKENHI-PROJECT-21K07788, KAKENHI-PROJECT-20H03651, KAKENHI-PROJECT-19K17381
[Journal Article] Kv3.1 channels regulate the rate of critical period plasticity2021
- Author(s)
  Matsuda Yoshi-Taka、Miyamoto Hiroyuki、Joho Rolf H.、Hensch Takao K
- Journal Title
  
  Neuroscience Research
  
  Volume: TBD Pages: 3-10
- DOI
  10.1016/j.neures.2021.04.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07577, KAKENHI-PROJECT-17H02195, KAKENHI-PROJECT-21K06436, KAKENHI-ORGANIZER-20H05914
[Journal Article] CRISPR/dCas9-based Scn1a gene activation in inhibitory neurons ameliorates epileptic and behavioral phenotypes of Dravet syndrome model mice2020
- Author(s)
  Yamagata Tetsushi、Raveau Matthieu、Kobayashi Kenta、Miyamoto Hiroyuki、Tatsukawa Tetsuya、Ogiwara Ikuo、Itohara Shigeyoshi、Hensch Takao K.、Yamakawa Kazuhiro
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 141 Pages: 104954-104954
- DOI
  10.1016/j.nbd.2020.104954
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08284, KAKENHI-PROJECT-18K07577
[Journal Article] Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility.2020
- Author(s)
  Hayase Y, Amano S, Hashizume K, Tominaga T, Miyamoto H, Kanno Y, Ueno-Inoue Y, Inoue T, Yamada M, Ogata S, Balan S, Hayashi K, Miura Y, Tokudome K, Ohno Y, Nishijo T, Momiyama T, Yanagawa Y, Takizawa A, Mashimo T, Serikawa T, Sekine A, Nakagawa E, Takeshita E, Yoshikawa T, Waga C, Inoue K, Goto YI, Nabeshima Y, et al.
- Journal Title
  
  Acta Neuropathol Commun.
  
  Volume: 8 Issue: 1 Pages: 206-206
- DOI
  10.1186/s40478-020-01082-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-20K06667, KAKENHI-PROJECT-20K06886, KAKENHI-PROJECT-18KK0307, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-17K07063, KAKENHI-PROJECT-17K07126, KAKENHI-PROJECT-18K07577, KAKENHI-PLANNED-16H06528, KAKENHI-PLANNED-16H06532, KAKENHI-PROJECT-18H02538
[Journal Article] Scn2a haploinsufficient mice display a spectrum of phenotypes affecting anxiety, sociability, memory flexibility and ampakine CX516 rescues their hyperactivity2019
- Author(s)
  Tatsukawa Tetsuya、Raveau Matthieu、Ogiwara Ikuo、Hattori Satoko、Miyamoto Hiroyuki、Mazaki Emi、Itohara Shigeyoshi、Miyakawa Tsuyoshi、Montal Mauricio、Yamakawa Kazuhiro
- Journal Title
  
  Molecular Autism
  
  Volume: 10 Issue: 1 Pages: 1-15
- DOI
  10.1186/s13229-019-0265-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07577, KAKENHI-PROJECT-17H01564, KAKENHI-PROJECT-16H06276
[Journal Article] Impaired cortico-striatal excitatory transmission triggers epilepsy2019
- Author(s)
  Miyamoto Hiroyuki、Tatsukawa Tetsuya、Shimohata Atsushi、Yamagata Tetsushi、Suzuki Toshimitsu、Amano Kenji、Mazaki Emi、Raveau Matthieu、Ogiwara Ikuo、Oba-Asaka Atsuko、Hensch Takao K.、Itohara Shigeyoshi、Sakimura Kenji、Kobayashi Kenta、Kobayashi Kazuto、Yamakawa Kazuhiro
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1917-1917
- DOI
  10.1038/s41467-019-09954-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01564, KAKENHI-PROJECT-18K06535, KAKENHI-PROJECT-18K07577, KAKENHI-PROJECT-19K08284, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18H02545
[Journal Article] DYRK1A-haploinsufficiency in mice causes autistic-like features and febrile seizures2018
- Author(s)
  Raveau Matthieu、Shimohata Atsushi、Amano Kenji、Miyamoto Hiroyuki、Yamakawa Kazuhiro
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 110 Pages: 180-191
- DOI
  10.1016/j.nbd.2017.12.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09848, KAKENHI-PROJECT-18K07577
[Journal Article] Variant Intestinal-Cell Kinase in Juvenile Myoclonic Epilepsy2018
- Author(s)
  Bailey Julia N.、de Nijs Laurence、Bai Dongsheng、Suzuki Toshimitsu、Miyamoto Hiroyuki、Yamakawa Kazuhiro、Lakaye Bernard、Delgado-Escueta Antonio V. et al.
- Journal Title
  
  New England Journal of Medicine
  
  Volume: 378 Issue: 11 Pages: 1018-1028
- DOI
  10.1056/nejmoa1700175
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253073, KAKENHI-PROJECT-18K07577, KAKENHI-PROJECT-15H02548, KAKENHI-PROJECT-16K15532
[Journal Article] Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice2018
- Author(s)
  Ogiwara Ikuo、Miyamoto Hiroyuki、Tatsukawa Tetsuya、Yamagata Tetsushi、Nakayama Tojo、Atapour Nafiseh、Miura Eriko、Mazaki Emi、Ernst Sara J.、Cao Dezhi、Ohtani Hideyuki、Itohara Shigeyoshi、Yanagawa Yuchio、Montal Mauricio、Yuzaki Michisuke、Inoue Yushi、Hensch Takao K.、Noebels Jeffrey L.、Yamakawa Kazuhiro
- Journal Title
  
  Communications Biology
  
  Volume: 1 Issue: 1 Pages: 1-16
- DOI
  10.1038/s42003-018-0099-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07577, KAKENHI-PROJECT-17H01564
[Journal Article] Variant Intestinal-Cell Kinase in Juvenile Myoclonic Epilepsy2018
- Author(s)
  Bailey Julia N.、de Nijs Laurence、Bai Dongsheng、Suzuki Toshimitsu、Miyamoto Hiroyuki、et al.
- Journal Title
  
  New England Journal of Medicine
  
  Volume: 378 Pages: 1018-1028
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09848
[Journal Article] Potentiation of excitatory synaptic transmission ameliorates aggression in mice with Stxbp1 haploinsufficiency2017
- Author(s)
  Miyamoto Hiroyuki、Shimohata Atsushi、Abe Manabu、Abe Teruo、Mazaki Emi、Amano Kenji、Suzuki Toshimitsu、Tatsukawa Tetsuya、Itohara Shigeyoshi、Sakimura Kenji、Yamakawa Kazuhiro
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 26 Issue: 24 Pages: 4961-4974
- DOI
  10.1093/hmg/ddx379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-17K19444, KAKENHI-PROJECT-15H04290, KAKENHI-PROJECT-15K09848, KAKENHI-PROJECT-16H06276
[Journal Article] Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism.2017
- Author(s)
  Shimohata A, Ishihara K, Hattori S, Miyamoto H, Morishita H, Ornthanalai G, Raveau M, Ebrahim AS, Amano K, Yamada K, Sago H, Akiba S, Mataga N, Murphy NP, Miyakawa T, Yamakawa K.
- Journal Title
  
  Exp Neurol
  
  Volume: S0014-4886(17) Pages: 30069-9
- DOI
  10.1016/j.expneurol.2017.03.009
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06462, KAKENHI-PROJECT-25242078, KAKENHI-PROJECT-25460077, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-15K09848
[Journal Article] Regulation of spinogenesis in mature Purkinje cells via mGluR/PKC-mediated phosphorylation of CaMKIIβ2017
- Author(s)
  Sugawara Takeyuki、Hisatsune Chihiro、Miyamoto Hiroyuki、Ogawa Naoko、Mikoshiba Katsuhiko
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 114 Issue: 26
- DOI
  10.1073/pnas.1617270114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-15K06761, KAKENHI-PROJECT-15K09848
[Journal Article] Elfn1 recruits presynaptic mGluR7 in trans and its loss results in seizures.2014
- Author(s)
  Naoko H. Tomioka, Hiroki Yasuda, Hiroyuki Miyamoto, Minoru Hatayama, Naoko Morimura, Yoshifumi Matsumoto, Toshimitsu Suzuki, Maya Odagawa, Yuri S. Odaka, Yoshimi Iwayama, Ji Won Um, Jaewon Ko, Yushi Inoue, Sunao Kaneko, Shinichi Hirose, Kazuyuki Yamada, Takeo Yoshikawa, Kazuhiro Yamakawa, Jun Aruga
- Journal Title
  
  Nature Communications
  
  Volume: 5 Issue: 1 Pages: 45011-16
- DOI
  10.1038/ncomms5501
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23500461, KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116002, KAKENHI-PROJECT-24249060, KAKENHI-PROJECT-24621012, KAKENHI-PUBLICLY-25110736, KAKENHI-PUBLICLY-25129708, KAKENHI-PROJECT-25640026, KAKENHI-PROJECT-25670481, KAKENHI-PROJECT-26430003
[Journal Article] A theory of the transition to critical period plasticity: inhibition selectively suppresses spontaneous activity.2013
- Author(s)
  Toyoizumi T, Miyamoto H, Yazaki-Sugiyama Y, Atapour N, Hensch TK, Miller KD.
- Journal Title
  
  Neuron
  
  Volume: 80 Issue: 1 Pages: 51-63
- DOI
  10.1016/j.neuron.2013.07.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24621012
[Journal Article] IP3R1 deficiency in the cerebellum/brainstem causes basal ganglia-independent dystonia by triggering tonic Purkinje cell firings in mice.2013
- Author(s)
  Hisatsune C, Miyamoto H, Hirono M, Yamaguchi N, Sugawara T, Ogawa N, Ebisui E, Ohshima T, Yamada M, Hensch TK, Hattori M, Mikoshiba K.
- Journal Title
  
  Front Neural Circuits.
  
  Volume: ７ Pages: 156-156
- DOI
  10.3389/fncir.2013.00156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500451, KAKENHI-PROJECT-24621012, KAKENHI-PROJECT-25221002
[Journal Article] Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome.2013
- Author(s)
  Ogiwara I, Iwasato T, Miyamoto H, Iwata R, Yamagata T, Mazaki E, Yanagawa Y, Tamamaki N, Hensch TK, Itohara S, Yamakawa K.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 22 Issue: 23 Pages: 4784-4804
- DOI
  10.1093/hmg/ddt331
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22115009, KAKENHI-PROJECT-24621012, KAKENHI-PROJECT-25461572
[Journal Article] Mouse with Na(v)1.1 haploinsufficiency, a model for Dravet syndrome, exhibits lowered sociability and learning impairment.2012
- Author(s)
  Ito S, Ogiwara I, Yamada K, Miyamoto H, Hensch TK, Osawa M, Yamakawa K.
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 49C Pages: 29-40
- DOI
  10.1016/j.nbd.2012.08.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24621012
[Journal Article] Serotonergic integration of circadian clock and ultradian sleep-wake cycles2012
- Author(s)
  Miyamoto H, Nakamaru-Ogiso E, Hamada K, Hensch TK.
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 32 Issue: 42 Pages: 14794-14803
- DOI
  10.1523/jneurosci.0793-12.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24621012
[Journal Article] Selective control of inhibitory synapse development by Slitrk3-PTPδ trans-synaptic interaction2012
- Author(s)
  Hideto Takahashi, Kei-ichi Katayama, Kazuhiro Sohya, Hiroyuki Miyamoto, Tuhina Prasad, Yoshifumi Matsumoto, Maya Ota, Hiroki Yasuda, Tadaharu Tsumoto, Jun Aruga, Ann Marie Craig
- Journal Title
  
  Nature Neuroscience
  
  Volume: 15 Issue: 3 Pages: 389-398
- DOI
  10.1038/nn.3040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21200016, KAKENHI-PROJECT-21240031, KAKENHI-PROJECT-23500461, KAKENHI-PROJECT-23700404, KAKENHI-PROJECT-23700457, KAKENHI-PROJECT-24621012, KAKENHI-PUBLICLY-23115523
[Journal Article] 睡眠とシナプス可塑性の相互作用2009
- Author(s)
  宮本浩行、ヘンシュ貴雄
- Journal Title
  
  生体の科学 60
  
  Pages: 260-268
- Data Source
  KAKENHI-PROJECT-20500364
[Journal Article] 睡眠とシナプス可塑性の相互作用2009
- Author(s)
  宮本浩行・ヘンシュ貴雄
- Journal Title
  
  生体の科学 60
  
  Pages: 260-268
- Data Source
  KAKENHI-PROJECT-20500364
[Journal Article] Efhc1 deficiency causes spontaneous myoclonus and increased seizure susceptibility.2009
- Author(s)
  Suzuki T, Miyamoto H, Nakahari T, Inoue I, Suemoto T, Jiang B, Hirota Y, Itohara S, Saido TC, Tsumoto T, Sawamoto K, Hensch TK, Delgado-Escueta AV, Yamakawa K
- Journal Title
  
  Hum Mol Genet. 18
  
  Pages: 1099-1109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500364
[Journal Article] Bidirectional interaction of sleep and synaptic plasticity : A view from visual cortex.2006
- Author(s)
  Miyamoto, H., Hensch, T.K.
- Journal Title
  
  Sleep and Biological Rhythms 4
  
  Pages: 35-43
- Data Source
  KAKENHI-PROJECT-17700374
[Journal Article] 徐波睡眠の発達と視床皮質回路の可塑性2006
- Author(s)
  宮本浩行, ヘンシュ貴雄
- Journal Title
  
  Clinical Neuroscience 24
  
  Pages: 1108-1111
- Data Source
  KAKENHI-PROJECT-17700374
[Journal Article] 神経系の可塑性・発達と睡眠2006
- Author(s)
  宮本浩行, ヘンシュ貴雄
- Journal Title
  
  Brain Medical 18
  
  Pages: 87-93
- Data Source
  KAKENHI-PROJECT-17700374
[Presentation] 大脳皮質興奮性神経伝達の低下によって生じる欠神てんかんの新たな神経回路メカニズム2021
- Author(s)
  宮本浩行
- Organizer
  てんかん財団第32回研究報告会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07577
[Presentation] 臨界期可塑性と睡眠の発達2021
- Author(s)
  宮本浩行, ヘンシュ貴雄
- Organizer
  日本睡眠学会第46回定期学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06436
[Presentation] 乳児難治性てんかん大田原症候群：二つの独立したモデルマウスの解析による2018
- Author(s)
  宮本浩行
- Organizer
  てんかん治療研究振興財団　研究報告会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07577
[Presentation] 乳児難治性てんかん大田原症候群：二つの独立したモデルマウスの解析によるてんかんと知的障害発症の神経メカニズムの解明2018
- Author(s)
  宮本浩行
- Organizer
  てんかん治療研究振興財団　第29回　研究報告会
- Invited
- Data Source
  KAKENHI-PROJECT-15K09848
[Presentation] Sleep strengthens local cortical connectivity through inhibition2013
- Author(s)
  Miyamoto H, Hensch TK
- Organizer
  35th Annual International Conference of the IEEE engineering in Medicine and Biological Society
- Place of Presentation
  大阪市
- Invited
- Data Source
  KAKENHI-PROJECT-24621012
[Presentation] An essential role of Elfn1 in the formation of hippocampal inhibitory neural circuits containing somatostatin-positive neurons2013
- Author(s)
  Tomioka NH, Miyamoto H, Hatayama M, , Morimura N, Matsumoto Y, Suzuki T, Odagawa MO, Odaka YS, Iwayama Y, Yamada K, Yoshikawa T, Yamakawa K, Aruga J
- Organizer
  Annual Meeting of Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24621012
[Presentation] セロトニン系によって統合されるサーカディアン生物時計と睡眠・覚醒2013
- Author(s)
  宮本浩行
- Organizer
  日本睡眠学会大38回定期学術集会
- Place of Presentation
  秋田市
- Invited
- Data Source
  KAKENHI-PROJECT-24621012
[Presentation] Nav1.1 haploinsufficient excitatory and inhibitory neurons play distinct roles in the epileptic pathology in Dravet syndrome model mice.2013
- Author(s)
  Ogiwara I, Iwasato T, Miyamoto H, Iwata R, Yamagata T, Mazaki E, Yanagawa Y, Tamamaki N, Hensch TK, Itohara S, Yamakawa K
- Organizer
  Annual Meeting of Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24621012
[Presentation] パルブアルブミン陽性介在性神経細胞特異的Scn1a遺伝子破壊によるてんかんモデルマウスの樹立2012
- Author(s)
  荻原郁夫　宮本浩行　眞崎恵美　玉巻伸章　ヘンシュ貴雄、山川和弘
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-24621012
[Presentation] 興奮と抑制信号を介した、睡眠による機能的結合の促進2012
- Author(s)
  宮本浩行、ヘンシュ貴雄
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-24621012
[Presentation] Increased seizure-susceptibility is caused by loss of Elfn1, an interneuron-specific LRR transmembrane protein2012
- Author(s)
  Tomioka NH, Miyamoto H, Odagawa M, Odaka YS, Hatayama M, Morimura N, MatsumotoY, Yamada K, Aruga J
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡市
- Invited
- Data Source
  KAKENHI-PROJECT-24621012
[Presentation] セロトニン系によって統合されるサーカディアン振動体と睡眠・覚醒交替2012
- Author(s)
  宮本浩行
- Organizer
  日本睡眠学会第37回定期学術集会
- Place of Presentation
  横浜市
- Invited
- Data Source
  KAKENHI-PROJECT-24621012
[Presentation] Selective deletion of the Scn1a gene encoding voltage-gated sodium channel α1 in parvalbumin positive cells in mice triggers epileptic seizures2012
- Author(s)
  荻原郁夫　宮本浩行　眞崎恵美　玉巻伸章　ヘンシュ貴雄、山川和弘
- Organizer
  第46回日本てんかん学会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24621012
[Presentation] セロトニンによって束ねられる睡眠・覚醒と24時間リズム2012
- Author(s)
  宮本浩行
- Organizer
  さきがけ　「脳神経回路の形成・動作と制御」領域　研究成果報告会
- Place of Presentation
  名古屋市
- Invited
- Data Source
  KAKENHI-PROJECT-24621012
[Presentation] マウス視覚野における睡眠・覚醒状態に依存した機能的神経結合の抑制系制御2011
- Author(s)
  宮本浩行・ヘンシュ貴雄
- Organizer
  日本生体医工学会大会
- Place of Presentation
  東京
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-20500364
[Presentation] マウス視覚野における2010
- Author(s)
  宮本浩行
- Organizer
  睡眠・覚醒に依存した機能的結合の抑制系による制御:シンポジウム:「包括脳ネットワーク」夏のワークショップ
- Place of Presentation
  北海道
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-20500364
[Presentation] マウス視覚野における、睡眠・覚醒に依存した機能的結合の抑制系による制御2010
- Author(s)
  宮本浩行
- Organizer
  「包括脳ネットワーク」夏のワークショップ
- Place of Presentation
  札幌市
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-20500364
[Presentation] ラット脳セロトニン除去による睡眠覚醒リズムと視交叉上核活動の機能的乖離2010
- Author(s)
  宮本浩行、濱田耕造
- Organizer
  日本神経科学学会
- Place of Presentation
  神戸市
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20500364
[Presentation] Functional dissociation between the circadian clock in the suprachiasmatic nucleus and sleep-wake cycle after brain serotonin depletion.2010
- Author(s)
  宮本浩行・濱田耕造
- Organizer
  日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20500364
[Presentation] Inhibitory control of state-dependent visual processing and functional connectivity in freely-behaving mouse visual cortex2008
- Author(s)
  Miyamoto H, Hensch TK
- Organizer
  日本神経科学会
- Place of Presentation
  東京
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-20500364
[Presentation] Neuronal Activity Patterns during Sleep and Plasticity2008
- Author(s)
  Hiroyuki Miyamoto, Takao K.Hensch
- Organizer
  Japanese-American Kavli Frontiers of Science Symposium.
- Place of Presentation
  Irvine, USA
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-20500364
[Presentation] 睡眠による視覚野機能的神経結合の促進と抑制性制御
- Author(s)
  宮本浩行、槌本佳子、ヘンシュ貴雄
- Organizer
  第18回視覚科学フォーラム特別企画シンポジウム
- Place of Presentation
  前橋工科大学　（群馬県　前橋市）
- Year and Date
  2014-08-18 – 2014-08-19
- Invited
- Data Source
  KAKENHI-PROJECT-24621012
[]

1. 天野賢治 (60333340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. SUZUKI Toshimitsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 安田浩樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 阿部学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 荻原郁夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 関根章博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 宮川剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 御子柴克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 久恒智博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 岩里琢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 山川和弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Miyamoto Hiroyuki 宮本 浩行

MIYAMOTO Hiroyuki 宮本 浩行

宮本 浩行 ミヤモト ヒロユキ

Research Projects

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Co-Researchers

腸内細菌は脳の老廃物排泄機構グリンパティックシステムにどのように影響しているかPrincipal Investigator

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発達期レム睡眠が育てるノンレム睡眠の成熟 ＝マウス臨界期操作によるアプローチ＝Principal Investigator

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Identification of the brain regions responsible for epilepsy and aggression induced by impaired synaptic transmissionPrincipal Investigator

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Circuit mechanisms for intractable epilepsy and intellectual disabilities caused by impairments of synaptic transmissionPrincipal Investigator

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Serotonergic integration of circadian clock and ultradian sleep-wake cyclesPrincipal Investigator

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State-dependent intracortical connectivity in the mouse visual cortexPrincipal Investigator

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視覚経験依存的な神経回路の再構成における睡眠の働きPrincipal Investigator

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[Book] 視能訓練学2018

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[Book] 睡眠科学2016

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[Book] 実験医学 脳神経回路リモデリング2015

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[Journal Article] Criticality supports cross-frequency cortical-thalamic information transfer during conscious states2024

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[Journal Article] CUX2 deficiency causes facilitation of excitatory synaptic transmission onto hippocampus and increased seizure susceptibility to kainate2022

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[Journal Article] Kv3.1 channels regulate the rate of critical period plasticity2021

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[Journal Article] CRISPR/dCas9-based Scn1a gene activation in inhibitory neurons ameliorates epileptic and behavioral phenotypes of Dravet syndrome model mice2020

Miyamoto Hiroyuki 宮本浩行

MIYAMOTO Hiroyuki 宮本浩行

宮本浩行ミヤモトヒロユキ

発達期レム睡眠が育てるノンレム睡眠の成熟＝マウス臨界期操作によるアプローチ＝Principal Investigator

[Book] 実験医学　脳神経回路リモデリング2015