Jin Denan 金徳男

… Alternative Names

KIN Tokunan 金徳男

JIN Denan 金徳男

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Researcher Number	90319533
Other IDs
External Links
Affiliation (Current)	2025: 大阪医科薬科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 大阪医科薬科大学, 医学部, 講師 2021 – 2023: 大阪医科薬科大学, 医学研究科, 講師 2017 – 2020: 大阪医科大学, 医学研究科, 講師 2017: 大阪医科大学, 大学院医学研究科, 講師 2014: 大阪医科大学, 医学部, 教授 … More 2008 – 2014: 大阪医科大学, 医学部, 講師 2002 – 2006: Osaka Medical College Faculty of Medicine Assistant Professor, 医学部, 講師 2001: 大阪医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General pharmacology / Basic Section 53040:Nephrology-related / Kidney internal medicine / General pharmacology Except Principal Investigator General pharmacology / Basic Section 48030:Pharmacology-related / Basic Section 56050:Otorhinolaryngology-related / Basic Section 47040:Pharmacology-related / General pharmacology / Ophthalmology
Keywords	Principal Investigator キマーゼ / キマーゼ阻害薬 / 人工血管 / 内膜肥厚 / 人工血管狭窄 / PTFE人工血管 / TGF-β1 / 遊走 / 線維芽細胞 / イヌ … More / アンジオテンシンII / PTFE / 新しい人工血管 / バスキュラーアクセス / コーティング / 人工血管素材 / 薬物治療 / バスキュラーアクセス不全 / 腎透析 / 機序 / 動静脈シャント狭窄 / 筋線維芽細胞 / 動静脈シャント / 線維芽細胞遊走 / 血管アクセス不全 / hepatic fibrosis / cardiac fibrosis / angiotensrn II / chymase / シャント / 心筋症 / 精製 / 心不全 / 肝臓線維化 / 心臓線維化 / dog / humster / cardiac function / arrhythmia / liverbility / ischemia-reperfusion / myocardial infarction / chymase inhibitor / ハムスター / 心機能 / 不整脈 / 生存率 / 虚血再灌流 / 心筋梗塞 / 国際情報交換 / 内腔狭窄 / グラフト / アンジオテンシン変換酵素(ACE) / 血管内膜肥厚 / PTEE / 狭窄 / グラシル … More Except Principal Investigator キマーゼ / 糖尿病 / 阻害薬 / 合併症 / MMP-9 / MMP-2 / VEGF / chymase / 高血圧 / 大動脈瘤 / 線維化 / 脂肪肝 / 高脂血症 / メタボリックシンドローム / 心臓 / 肥満細胞 / アンジオテンシンII / 口腔癌 / 唾液腺癌 / 網膜症 / 腎障害 / アンジオテンシンⅡ / 白内障 / 非アルコール性脂肪性肝炎 / 脂質異常症 / NASH / tumor / angiogenesis / mast cell / マトリックスメタロプロテイネース(MMP)-2 / Vascular Endothelial Growth Factor(VEGF) / 腫瘍 / 血管新生 / angiotensin II receptor blocker / angiotensin converting enzyme / angiotensin II / aortic aneurysm / cardiac function / myocardial infarction / chymase inhibitor / アンジオテンシンII受容体拮抗薬 / アンジオテンシン変換酵素 / アンジオテンシン / 心機能 / 心筋梗塞 / キマーゼ阻害薬 / マイトマイシン / 線維芽細胞 / ゼラチンハイドロゲル / 眼圧 / 安全 / 濾過胞 / 徐放 / マイトマイシンC / ハイドロゲル / 濾過手術 / 緑内障 / 臓器線維化 / 内皮機能障害 / 肝線維化 / 動脈硬化 / 臓器障害 / 組織線維化 / 血管 / 組織繊維化 / Transforming growth factor-β Less

Pathophysiological role of chymase in cardiac fibrosis
- Principal Investigator
  
  高井真司
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Mast cells and therapeutic strategies in salivary gland adenoid cystic carcinoma and oral cancer.
- Principal Investigator
  
  東野正明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Pathophysiological role of chymase in diabetic complications
- Principal Investigator
  
  高井真司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Development of artificial blood vessels made from new materials for use in renal dialysis vascular accessPrincipal Investigator
- Principal Investigator
  
  Jin Denan
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Searching for the mechanisms and therapeutics in the pathogenesis of stenosis after the implantation of arteriovenous ePTFE artificial and auto blood vessel grafts.Principal Investigator
- Principal Investigator
  
  Jin Denan
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Osaka Medical College
Role of chymase on development and progression of organ damage induced by metabolic syndrome
- Principal Investigator
  
  TAKAI Shinji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka Medical College
Mechanistic and therapeutic investigation of the outside fibroblasts involving the inner neointima formation after implantation of PTFE grafts.Principal Investigator
- Principal Investigator
  
  JIN DENAN
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka Medical College
Establishment of sustained drug delivery system to inhibit scaring and synechia after glaucoma surgery
- Principal Investigator
  
  KOJIMA Shota
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Osaka Medical College
Investigation of the mechanisms involving PTFE graft occlusion and searching its pharmacotherapeutics with chymase inhibitorPrincipal Investigator
- Principal Investigator
  
  JIN Denan
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka Medical College
Pathophysiological role of chymase in complications of metabolic syndrome
- Principal Investigator
  
  TAKAI Shinji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka Medical College
New Aspects of Mast-Cell Derived Chymase -Roles of Chymase in Vascularization and Tumor Development-
- Principal Investigator
  
  MIYAZAKI Mizuo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka Medical College
キマーゼの心血管組識線維化における病態生理学的役割
- Principal Investigator
  
  TAKAI Shinji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Osaka Medical College
Roles of chymase in the development of cardiac remodeling during heart failure progression.Principal Investigator
- Principal Investigator
  
  JIN Denan
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka Medical College
Pathophysiological roles of chymase on cardiovascular disease
- Principal Investigator
  
  MIYAZAKI Mizuo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka Medical College
Pathophysiological roles of the cardic renin-angiotensin system after myocardial infarction-Chymase dependent angiotensin II-forming pathway and myocardial infarction-Principal Investigator
- Principal Investigator
  
  JIN Denan
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka Medical College

[Journal Article] Tryptase-Positive Mast Cells Promote Adipose Fibrosis in Secondary Lymphedema through PDGF2023
- Author(s)
  Nuri Takashi、Jin Denan、Takai Shinji、Ueda Koichi
- Journal Title
  
  Current Issues in Molecular Biology
  
  Volume: 45 Issue: 10 Pages: 8027-8039
- DOI
  10.3390/cimb45100507
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08601
[Journal Article] Chymase Inhibition Resolves and Prevents Deep Vein Thrombosis Without Increasing Bleeding Time in the Mouse Model2023
- Author(s)
  Lapointe Catherine、Vincent Laurence、Gigu?re Hugo、Auger‐Messier Mannix、Schwertani Adel、Jin Denan、Takai Shinji、Pejler Gunnar、Sirois Martin G.、Tinel Hanna、Heitmeier Stefan、D'Orl?ans‐Juste Pedro
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 12 Issue: 4
- DOI
  10.1161/jaha.122.028056
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08601
[Journal Article] Increased Chymase-Positive Mast Cells in High-Grade Mucoepidermoid Carcinoma of the Parotid Gland2023
- Author(s)
  Nishimura Hiromi、Jin Denan、Kinoshita Ichita、Taniuchi Masataka、Higashino Masaaki、Terada Tetsuya、Takai Shinji、Kawata Ryo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 9 Pages: 8267-8267
- DOI
  10.3390/ijms24098267
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08601
[Journal Article] Effects of Angiotensin Receptor Blockers on Streptozotocin-Induced Diabetic Cataracts2023
- Author(s)
  Ishigooka Gaku、Mizuno Hiroshi、Oosuka Shou、Jin Denan、Takai Shinji、Kida Teruyo
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 12 Issue: 20 Pages: 6627-6627
- DOI
  10.3390/jcm12206627
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06639, KAKENHI-PROJECT-18K09428
[Journal Article] Plasma Chymase Activity Reflects the Change in Hemodynamics Observed after the Surgical Treatment of Patent Ductus Arteriosus in Dogs2022
- Author(s)
  Shimada Kazumi、Hamabe Lina、Hirose Miki、Watanabe Momoko、Yokoi Aimi、Takeuchi Aki、Ozai Yusuke、Yoshida Tomohiko、Takai Shinji、Jin Denan、Kocaturk Meric、Uehara Katsumi、Tanaka Ryou
- Journal Title
  
  Veterinary Sciences
  
  Volume: 9 Issue: 12 Pages: 682-682
- DOI
  10.3390/vetsci9120682
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08601
[Journal Article] Pathophysiological Role of Chymase-Activated Matrix Metalloproteinase-92022
- Author(s)
  Takai Shinji、Jin Denan
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 10 Pages: 2499-2499
- DOI
  10.3390/biomedicines10102499
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08601
[Journal Article] Design, synthesis, and evaluation of new vanin-1 inhibitors based on RR62022
- Author(s)
  Yoneyama Hiroki、Hosohata Keiko、Jin Denan、Yoshida Iroha、Toyoda Miyui、Kitamura Ikuko、Takai Shinji、Usami Yoshihide
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 65 Pages: 116791-116791
- DOI
  10.1016/j.bmc.2022.116791
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08601
[Journal Article] Activation of Mast-Cell-Derived Chymase in the Lacrimal Glands of Patients with IgG4-Related Ophthalmic Disease2022
- Author(s)
  Fujita Yasushi、Jin Denan、Mimura Masashi、Sato Yohei、Takai Shinji、Kida Teruyo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 5 Pages: 2556-2556
- DOI
  10.3390/ijms23052556
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09428, KAKENHI-PROJECT-20K08601
[Journal Article] In Vivo and In Vitro Evaluation of Urinary Biomarkers in Ischemia/Reperfusion-Induced Kidney Injury2021
- Author(s)
  Hosohata Keiko、Jin Denan、Takai Shinji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 21 Pages: 11448-11448
- DOI
  10.3390/ijms222111448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08601, KAKENHI-PROJECT-21K06722
[Journal Article] Expression of Lymphatic Markers in the Berger’s Space and Bursa Premacularis2021
- Author(s)
  Morishita Seita、Sato Takaki、Oosuka Shou、Horie Taeko、Kida Teruyo、Oku Hidehiro、Nakamura Kimitoshi、Takai Shinji、Jin Denan、Ikeda Tsunehiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 4 Pages: 2086-2086
- DOI
  10.3390/ijms22042086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09428, KAKENHI-PROJECT-20K08601
[Journal Article] Chymase as a Novel Therapeutic Target in Acute Pancreatitis2021
- Author(s)
  Kuramoto Toru、Jin Denan、Komeda Koji、Taniguchi Kohei、Hirokawa Fumitoshi、Takai Shinji、Uchiyama Kazuhisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 22 Pages: 12313-12313
- DOI
  10.3390/ijms222212313
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08601
[Journal Article] Decreased Presence of Mast Cells in the Bursa Premacularis of Proliferative Diabetic Retinopathy.2021
- Author(s)
  Ikeda T, Nakamura K, Morishita S, Sato T, Horie T, Kida T, Oku H, Takai S, Jin D.
- Journal Title
  
  Ophthalmic Res.
  
  Volume: 64. Issue: 6 Pages: 1002-1012
- DOI
  10.1159/000518438
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10002, KAKENHI-PROJECT-18K09428, KAKENHI-PROJECT-20K08601
[Journal Article] Postoperative Adhesion Prevention Using a Biodegradable Temperature-Responsive Injectable Polymer System and Concomitant Effects of the Chymase Inhibitor2021
- Author(s)
  Yoshizaki Yuta、Nagata Takuya、Fujiwara Soichiro、Takai Shinji、Jin Denan、Kuzuya Akinori、Ohya Yuichi
- Journal Title
  
  ACS Applied Bio Materials
  
  Volume: 4 Issue: 4 Pages: 3079-3088
- DOI
  10.1021/acsabm.0c01467
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K18389, KAKENHI-PROJECT-20H00670, KAKENHI-PROJECT-20K08601
[Journal Article] Increase in Chymase-Positive Mast Cells in Recurrent Pleomorphic Adenoma and Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland2021
- Author(s)
  Kinoshita Ichita、Jin Denan、Higashino Masaaki、Terada Tetsuya、Kurisu Yoshitaka、Takai Shinji、Kawata Ryo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 23 Pages: 12613-12613
- DOI
  10.3390/ijms222312613
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08601, KAKENHI-PROJECT-21K09641
[Journal Article] Glaucocalyxin A Ameliorates Hypoxia/Reoxygenation-Induced Injury in Human Renal Proximal Tubular Epithelial Cell Line HK-2 Cells2021
- Author(s)
  Hosohata Keiko、Jin Denan、Takai Shinji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 1 Pages: 446-446
- DOI
  10.3390/ijms23010446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08601, KAKENHI-PROJECT-21K06722
[Journal Article] Impaired function of aorta and perivascular adipose tissue in IL-18-deficient mice.2019
- Author(s)
  Li W, Jin D, Takai S, Hayakawa T, Ogata J, Yamanishi K, Yamanishi H, Okamura H.
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 317 Issue: 5 Pages: H1142-H1156
- DOI
  10.1152/ajpheart.00813.2018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09741
[Journal Article] Effects of Regorafenib, a Multi-Kinase Inhibitor, on Conjunctival Scarring in a Canine Filtration Surgery Model in Comparison With Mitomycin-C2019
- Author(s)
  Nemoto E, Kojima S, Sugiyama T, Jin D, Takai S, Maeda M, Kohmoto R, Ueki M, Oku H, Ikeda T.
- Journal Title
  
  Int J Mol Sci .
  
  Volume: 21 Issue: 1 Pages: 63-63
- DOI
  10.3390/ijms21010063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09741, KAKENHI-PROJECT-17K11496
[Journal Article] Involvement of premacular mast cells in the pathogenesis of macular diseases.2019
- Author(s)
  Sato T, Morishita S, Horie T, Fukumoto M, Kida T, Oku H, Nakamura K, Takai S, Jin D, Ikeda T.
- Journal Title
  
  PLoS One.
  
  Volume: 14 Issue: 2 Pages: e0211438-e0211438
- DOI
  10.1371/journal.pone.0211438
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09741, KAKENHI-PROJECT-18K09428
[Journal Article] A Chymase Inhibitory RNA Aptamer Improves Cardiac Function and Survival after Myocardial Infarction2019
- Author(s)
  Jin Denan、Takai Shinji、Nonaka Yosuke、Yamazaki Satoko、Fujiwara Masatoshi、Nakamura Yoshikazu
- Journal Title
  
  Molecular Therapy - Nucleic Acids
  
  Volume: 14 Pages: 41-51
- DOI
  10.1016/j.omtn.2018.11.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06709, KAKENHI-PROJECT-17K09741
[Journal Article] Hypermetabolism of Glutathione, Glutamate and Ornithine via Redox Imbalance in Methylglyoxal-Induced Peritoneal Injury Rats2019
- Author(s)
  Hirahara I, Kusano E, Jin D, Takai S.
- Journal Title
  
  J Biochem .
  
  Volume: 167 Pages: 185-194
- DOI
  10.1093/jb/mvz077
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09741
[Journal Article] Comparison of a chymase inhibitor and hyaluronic acid/carboxymethylcellulose (Seprafilm) in a novel peritoneal adhesion model in rats.2019
- Author(s)
  Ozeki M, Jin D, Miyaoka Y, Masubuchi S, Hirokawa F, Hayashi M, Takai S, Uchiyama K.
- Journal Title
  
  PLoS One.
  
  Volume: 14 Issue: 1 Pages: e0211391-e0211391
- DOI
  10.1371/journal.pone.0211391
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09741
[Journal Article] Chymase Inhibitor as a Novel Therapeutic Agent for Non-alcoholic Steatohepatitis.2018
- Author(s)
  Takai S, Jin D.
- Journal Title
  
  Front Pharmacol
  
  Volume: 9 Pages: 144-144
- DOI
  10.3389/fphar.2018.00144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08251
[Journal Article] Vanin-1 in Renal Pelvic Urine Reflects Kidney Injury in a Rat Model of Hydronephrosis.2018
- Author(s)
  Hosohata K, Jin D, Takai S, Iwanaga K.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19 Issue: 10 Pages: 3186-3186
- DOI
  10.3390/ijms19103186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09741, KAKENHI-PROJECT-18K06768
[Journal Article] A novel hamster nonalcoholic steatohepatitis model induced by a high-fat and high-cholesterol diet2018
- Author(s)
  Miyaoka Y, Jin D, Tashiro K, Masubuchi S, Ozeki M, Hirokawa F, Hayashi M, Takai S, Uchiyama K.
- Journal Title
  
  Exp. Anim.
  
  Volume: 67 Issue: 2 Pages: 239-247
- DOI
  10.1538/expanim.17-0126
- NAID
  130006733605
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08251, KAKENHI-PROJECT-26860176, KAKENHI-PROJECT-17K09443, KAKENHI-PROJECT-17K09741
[Journal Article] Periostin antisense oligonucleotide prevents adhesion formation after surgery in mice2017
- Author(s)
  Takai Shinji、Yoshino Masafumi、Takao Kazumasa、Yoshikawa Kazunori、Jin Denan
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 133 Issue: 2 Pages: 65-69
- DOI
  10.1016/j.jphs.2016.10.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09741
[Journal Article] Chymase inhibitor prevents the development and progression of?non-alcoholic steatohepatitis in rats fed a high-fat and high-cholesterol diet2017
- Author(s)
  Miyaoka Yuta、Jin Denan、Tashiro Keitaro、Komeda Koji、Masubuchi Shinsuke、Hirokawa Fumitoshi、Hayashi Michihiro、Takai Shinji、Uchiyama Kazuhisa
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 134 Issue: 3 Pages: 139-146
- DOI
  10.1016/j.jphs.2017.04.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09741, KAKENHI-PROJECT-15K08251, KAKENHI-PROJECT-26860176
[Journal Article] Effects of Gelatin Hydrogel Containing Anti-Transforming Growth Factor-β Antibody in a Canine Filtration Surgery Model2017
- Author(s)
  Maeda Michiko、Kojima Shota、Sugiyama Tetsuya、Jin Denan、Takai Shinji、Oku Hidehiro、Kohmoto Ryohsuke、Ueki Mari、Ikeda Tsunehiko
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18 Issue: 5 Pages: 985-985
- DOI
  10.3390/ijms18050985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09741
[Journal Article] Improvement of cardiovascular remodelling by chymase inhibitor2016
- Author(s)
  Takai S, Jin D.
- Journal Title
  
  Clin Exp Pharmacol Physiol
  
  Volume: 43 Issue: 4 Pages: 387-393
- DOI
  10.1111/1440-1681.12549
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08251
[Journal Article] Recombinant human soluble thrombomodulin improved lipopolysaccharide/d-galactosamine-induced acute liver failure in mice2015
- Author(s)
  Osumi W, Jin D, Imai Y, Tashiro K, Li ZL, Otsuki Y, Maemura K, Komeda K, Hirokawa F, Hayashi M, Takai S, Uchiyama K.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 129 Issue: 4 Pages: 233-239
- DOI
  10.1016/j.jphs.2015.11.007
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08251
[Journal Article] Effects of Gelatin Hydrogel Loading Mitomycin C on Conjunctival Scarring in a Canine Filtration Surgery Model2015
- Author(s)
  Shota Kojima, Tetsuya Sugiyama, Shinji Takai, Denan Jin, Mari Ueki, Hidehiro Oku, Yasuhiko Tabata, Tsunehiko Ikeda
- Journal Title
  
  Investigative Ophthalmology and Visual Science
  
  Volume: 56 Issue: 4 Pages: 2601-2601
- DOI
  10.1167/iovs.15-16486
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592684
[Journal Article] Significance of vascular dipeptidyl peptidase-4 inhibition on vascular protection in Zucker diabetic fatty rats.2014
- Author(s)
  Takai S, Sakonjo H, Jin D.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 125 Pages: 386-393
- NAID
  130004677797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590336
[Journal Article] Chymase inhibition improves vascular dysfunction and survival in stroke-prone spontaneously hypertensive rats.2014
- Author(s)
  Takai S, Jin D, Chen H, Li W, Yamamoto H, Yamanishi K, Miyazaki M, Higashino H, Yamanishi H, Okamura H.
- Journal Title
  
  J Hypertens
  
  Volume: 32 Issue: 8 Pages: 1637-1648
- DOI
  10.1097/hjh.0000000000000231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590336
[Journal Article] Significance of matrix metalloproteinase-9 inhibition by imidapril for prevention of abdominal aortic aneurysms in angiotensin II type 1 receptor-knockout mice.2013
- Author(s)
  Takai S, Jin D, Yamamoto D, Li ZL, Otsuki Y, Miyazaki M.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 123 Pages: 185-194
- NAID
  130003382588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590336
[Journal Article] Angiotensin II promotes aortic valve thickening independent of elevated blood pressure I apolipoprotein-E deficientmice2013
- Author(s)
  Tomohiro Fujisaka,Toshiaki Hanafusa,Nobukazu Ishizaka
- Journal Title
  
  Atherosclerosis
  
  Volume: 226(1) Issue: 1 Pages: 82-7
- DOI
  10.1016/j.atherosclerosis.2012.10.055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590770, KAKENHI-PROJECT-24590336
[Journal Article] Chymase inhibition attenuates lipopolysaccharide/ d-galactosamine-induced acute liver failure in hamsters2013
- Author(s)
  Imai Y, Takai S, Jin D, Komeda K, Tashiro K, Li ZL, Otsuki Y, Okamura H, Hayashi M, Uchiyama K.
- Journal Title
  
  Pharmacology
  
  Volume: 40 Issue: 1-2 Pages: 832-840
- DOI
  10.1159/000357684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590313, KAKENHI-PROJECT-24590336
[Journal Article] Chymase inhibition attenuates monocrotaline-induced sinusoidal obstruction syndrome in hamsters.2013
- Author(s)
  Masubuchi S, Komeda K, Takai S, Jin D, Tashiro K, Li ZL, Otsuki Y, Okamura H, Hayashi M, Uchiyama K
- Journal Title
  
  Curr Med Chem
  
  Volume: 20 Pages: 2723-2729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590336
[Journal Article] Powerful vascular protection by combining cilnidipine with valsartan in stroke-prone, spontaneously hypertensive rats.2013
- Author(s)
  Takai S, Jin D, Aritomi S, Niinuma K, Miyazaki M.
- Journal Title
  
  Hypertens Res
  
  Volume: 36 Issue: 4 Pages: 342-348
- DOI
  10.1038/hr.2012.187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590336
[Journal Article] Significance of the vascular concentration of angiotensin II-receptor blockers on the mechanism of lowering blood pressure in spontaneously hypertensive rats.2013
- Author(s)
  Takai S, Jin D, Sakonjo H, Takubo T, Nakanishi T.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 123 Pages: 371-379
- NAID
  130003382617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590336
[Journal Article] Chymase inhibitor ameliorates hepatic steatosis and fibrosis on established non-alcoholic steatohepatitis in hamsters fed a methionine- and choline-deficient diet.2013
- Author(s)
  Masubuchi S, Takai S, Jin D, Tashiro K, Komeda K, Li ZL, Otsuki Y, Okamura H, Hayashi M, Uchiyama K.
- Journal Title
  
  Hepatol Res
  
  Volume: 印刷中 Issue: 9 Pages: 970-978
- DOI
  10.1111/hepr.12042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590313, KAKENHI-PROJECT-23591999, KAKENHI-PROJECT-24590336
[Journal Article] Multiple mechanisms for the action of chymase inhibitors.2012
- Author(s)
  Takai S, Jin D, Miyazaki M.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 118 Pages: 311-316
- NAID
  10030455328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590336
[Journal Article] Outside fibroblasts play a key role in the development of inner neointima after the implantation of polytetrafluoroethylene grafts.2012
- Author(s)
  Jin D, Takai S, Li Z, Sakonjo H, Otsuki Y, Shibayama Y, Miyazaki M.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 119 Pages: 139-149
- NAID
  10030828453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590336
[Journal Article] NOX1/NADPH oxidase is involved in endotoxin-induced cardiomyocyte spoptosis.2012
- Author(s)
  Matsuno K, Iwata K, Matsumoto M, Katsuyama M, Cui W, Murata A, Nakamura H, Ibi M, Ikami K, Zhang J, Matoba S, Jin D, Takai S, Matsubara H, Matsuda N, Yabe-Nishimura C
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 53 Issue: 9 Pages: 1718-1728
- DOI
  10.1016/j.freeradbiomed.2012.08.590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500445, KAKENHI-PROJECT-24590336
[Journal Article] Targets of chymase inhibitors2011
- Author(s)
  Takai S, Jin D, Miyazaki M.
- Journal Title
  
  Expert Opin Ther Targets
  
  Volume: 15 Pages: 519-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590295
[Journal Article] Effects of gelatin hydrogel containing chymase inhibitor on scarring in a canine filtration surgery model2011
- Author(s)
  Kojima S, Sugiyama T, Takai S, Jin D, et al.
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 52 Pages: 7672-7680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590295
[Journal Article] Chymase as an important target for preventing complications of metabolic syndrome.2010
- Author(s)
  Takai S, Jin D, Miyazaki M
- Journal Title
  
  Curr Med Chem 17
  
  Pages: 3223-3229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590265
[Journal Article] Chymase as an important target for preventing complications of metabolic syndrome2010
- Author(s)
  Takai S, Jin D, Miyazaki M.
- Journal Title
  
  Curr Med Chem
  
  Volume: 17 Pages: 3223-3229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590295
[Journal Article] Long-term angiotensin II blockade may improve not only hyperglycemia but also age-associated cardiac fibrosis2009
- Author(s)
  Jin, et al
- Journal Title
  
  J Pharmacol Sci 109
  
  Pages: 275-284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590295
[Journal Article] Long-term angiotensin II blockade may improve not only hyperglycemia but also age-associated cardiac fibrosis.2009
- Author(s)
  Jin D, Takai S, et al
- Journal Title
  
  J Pharmacol Sci 109(2)
  
  Pages: 275-284
- NAID
  10025734617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590265
[Journal Article] Long-term angiotensin II blockade may improve not only hyperglycemi a but also age-associated cardiac fibrosis2009
- Author(s)
  Jin Denan (金徳男)
- Journal Title
  
  J. Pharmacol. Sci. 109
  
  Pages: 275-284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590265
[Journal Article] Effects of chymase inhibitor on angiotensin II-induced abdominal aortic aneurysm development in apolipoprotein E-deficient mice2009
- Author(s)
  Inoue N, Jin D, Takai S, et al.
- Journal Title
  
  Atherosclerosis
  
  Volume: 204(2) Pages: 359-364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590295
[Journal Article] Chymase-dependent conversion of exogenously administered big endothelin-1 in the mouse in vivo.2009
- Author(s)
  Simard E, Jin D, Takai S, et al
- Journal Title
  
  J Pharmacol Exp Ther 328(2)
  
  Pages: 540-548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590265
[Journal Article] Chymase-dependent conversion of exogenously administered big endothelin-1 in the mouse in vivo2009
- Author(s)
  Simard E, Jin D, Takai S, et al
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 328(2) Pages: 540-548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590295
[Journal Article] Effects of chymase inhibitor on angiotensin II-induced abdominal aortic aneurysm development in apolipoprotein E-deficient mice.2009
- Author(s)
  Inoue N, Jin D, Takai S, et al
- Journal Title
  
  Atherosclerosis 204(2)
  
  Pages: 359-364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590265
[Journal Article] Chymase plays an important role in left ventricular remodeling induced by intermittent hypoxia in mice.2009
- Author(s)
  Matsumoto C, Jin D, Takai S, et al
- Journal Title
  
  Hypertension 54(1)
  
  Pages: 164-171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590265
[Journal Article] Long-term angiotensin II blockade may improve not only hyperglycemia but also age-associated cardiac fibrosis2009
- Author(s)
  Jin D, Takai S, et al.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 109(2) Pages: 275-284
- NAID
  10025734617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590295
[Journal Article] Effect of Chymase Inhibition on the Arteriovenous Fistula Stenosis in Dogs.2005
- Author(s)
  Jin D
- Journal Title
  
  J Am Soc Nephrol. (in press)
- Data Source
  KAKENHI-PROJECT-15590240
[Journal Article] Effect of chymase inhibition on the artheriovenous fistula stenosis in dog2005
- Author(s)
  Jin D
- Journal Title
  
  Journal of American Society of Nephrology 16・4
  
  Pages: 1024-1034
- Data Source
  KAKENHI-PROJECT-16659068
[Journal Article] The effect of chymase inhibition on the arteriovenous fistula stenosis in dogs2005
- Author(s)
  Jin D
- Journal Title
  
  J Am Soc Nephrol 16
  
  Pages: 1024-1034
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590240
[Journal Article] The effect of chymase inhibition on the arteriovenous fistula stenosis in dogs2005
- Author(s)
  Jin D
- Journal Title
  
  J Am Soc Nephrol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370038
[Journal Article] An antiarrhythmic effect of a chymase inhibitor after myocardial infarction2004
- Author(s)
  Jin D
- Journal Title
  
  J Pharmacol Exp Ther 309
  
  Pages: 490-497
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370038
[Journal Article] An antiarrhythmic effect of a chymase inhibitor after myocardial infarction2004
- Author(s)
  Jin D
- Journal Title
  
  J Pharmacol Exp Ther 909
  
  Pages: 490-497
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370038
[Journal Article] An antiarrhythmic effect of a chymase inhibitor after myocardial infarction2004
- Author(s)
  Jin D
- Journal Title
  
  J Pharmacol Exp Ther 309
  
  Pages: 490-497
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590240
[Journal Article] An antiarrhythmic effect of a chymase inhibitor after myocardial infarction2004
- Author(s)
  Jin D
- Journal Title
  
  J Phamacol Exp Ther 909
  
  Pages: 490-497
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590240
[Journal Article] An antiarrhythmic effect of a chymase inhibitor after myocardial infarction.2004
- Author(s)
  Jin D
- Journal Title
  
  J Pharmacol Exp Ther. 309
  
  Pages: 490-497
- Data Source
  KAKENHI-PROJECT-15590240
[Journal Article] An antiarrhythmic effect of a shymase inhibitor after myocardial infarction2004
- Author(s)
  JIn D
- Journal Title
  
  J Pharmacol Exp Ther 3009
  
  Pages: 490-497
- Data Source
  KAKENHI-PROJECT-14370038
[Journal Article] Impact of chymase inhibitor on cardiac function and survival after myocardial infarction2003
- Author(s)
  Jin D
- Journal Title
  
  Cardiovasc Res 60
  
  Pages: 417-420
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370038
[Journal Article] Impact of chymase inhibitor on cardiac function and survival after myocardial infarction2003
- Author(s)
  Jin D
- Journal Title
  
  Cardiovasc Res 60
  
  Pages: 417-420
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590240
[Journal Article] Outside fibroblasts play a key role in the development of Inner neointima after the implantation of polytetrafluoroethylene grafts
- Author(s)
  Jin D, Takai S, Li Z, et al.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: (in press)
- NAID
  10030828453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590295
[Presentation] 糖尿病ラットにおけるヒシ・ルテインによる白内障進行抑制と網膜や大血管への影響2023
- Author(s)
  水野博史、石郷岡岳、金徳男、髙井真司、大里崇之、大須賀翔、佐藤孝樹、喜田照代
- Organizer
  第127回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-22K06639
[Presentation] 抗キマーゼアプタマーによる心筋梗塞後の心機能および生存率の改善効果2019
- Author(s)
  野中　洋介、金　徳男、高井　真司、藤原　将寿、中村　義一
- Organizer
  日本核酸医薬学会第５回年会
- Data Source
  KAKENHI-PROJECT-17K09741
[Presentation] Effect of an anti-chymase specific aptamer on cardiac function after myocardial infarction2018
- Author(s)
  Denan Jin, Shinji Takai, Yosuke Nonaka2), Satoko Yamazaki, Masatoshi Fujiwara, Yoshikazu Nakamura
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09741
[Presentation] Expression profile of mast cell chymase in stenotic lesions from patients with hemodialysis vascular access failure.2018
- Author(s)
  Denan Jin, Hyogo Nakakura, Yoichiro Maeda, Taketoshi Kanemiya, Nobuhisa Shibahara, Shinji Takai
- Organizer
  第９０回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K09741
[Presentation] キマーゼ阻害薬を用いたシャント狭窄予防の試み（第３報）2017
- Author(s)
  金　徳男、金宮健翁、前田陽一郎、中倉兵庫、柴原伸久、高井真司
- Organizer
  第62回日本透析医学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-17K09741
[Presentation] 術後腹部癒着に対するペリオスチンアンチセンスオリゴヌクレオチドの有効性2017
- Author(s)
  金　徳男、高井　真司、吉野　雅文、高尾　和正、吉川　寿徳
- Organizer
  日本核酸医薬学会第３回年会
- Data Source
  KAKENHI-PROJECT-17K09741
[Presentation] 新規核酸製剤（アプタマー）によるキマーゼ阻害と心筋梗塞後の心機能改善効果2017
- Author(s)
  金　徳男、高井真司、野中洋介、山崎聡子、藤原将寿、中村義一
- Organizer
  第27回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-17K09741
[Presentation] Chymase inhibitor prevents the development and progression of non-alcoholic steatohepatitis in rats fed a high-fat and high-cholesterol diet.2017
- Author(s)
  Miyaoka Y, Jin D, Tashiro K, Komeda K, Masubuchi S, Hirokawa F, Hayashi M, Takai S, Uchiyama K.
- Organizer
  Digestive Disease Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08251
[Presentation] 2.Effect of recombinant human soluble thrombomodulin in lipopolysaccharide/D-galactosamine-induced acute liver failure in mice2016
- Author(s)
  Osumi W, Jin D, Imai Y, Miyaoka Y, Tashiro K, Komeda K ,Hirokawa F, Hayashi M, Takai S, Nishiguchi K, Uchiyama K.
- Organizer
  Digestive Disease Week 2016
- Place of Presentation
  サンディエゴ（米国）
- Year and Date
  2016-05-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08251
[Presentation] 非アルコール性脂肪性肝炎におけるキマーゼ阻害薬の重要性2016
- Author(s)
  宮岡雄太、金徳男、田代圭太郎、米田浩二、廣川文鋭、林道廣、髙井真司、内山和久
- Organizer
  第21回日本病態プロテアーゼ学会　2016年8月5-6日
- Place of Presentation
  千里ライフサイエンスセンター（大阪府吹田市）
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-15K08251
[Presentation] 非アルコール性脂肪性肝炎に対するキマーゼ阻害薬の有用性2016
- Author(s)
  宮岡雄太、金徳男、田代圭太郎、米田浩二、廣川文鋭、林道廣、髙井真司、内山和久
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都大学百周年時計台記念館（京都府京都市）
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-15K08251
[Presentation] マイトマイシンC(MMC)包含 Gelatin Hydrogelの緑内障濾過手術への応用:MMC単独との比較2014
- Author(s)
  小嶌祥太、杉山哲也、金徳男、高井真司、植木麻理、池田恒彦、田畑靖彦
- Organizer
  第118回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24592684
[Presentation] ＰＴＦＥ人工血管移植後の血管周囲線維芽細胞の遊走とその管腔内内膜肥厚の形成2013
- Author(s)
  金　徳男、高井　真司、宮崎　瑞夫
- Organizer
  第４２回日本心脈管作動物質学会
- Place of Presentation
  奈良県新公会堂（奈良県）
- Data Source
  KAKENHI-PROJECT-24590336
[Presentation] ＰＴＦＥ人工血管移植後の血管内膜肥厚における外膜側線維芽細胞の役割2013
- Author(s)
  金　徳男、高井　真司、宮崎　瑞夫
- Organizer
  第８６回　日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-24590336
[Presentation] Chymase as a useful target to prevent abdominal aortic aneurysm.2011
- Author(s)
  Takai S, Jin D, Miyazaki M
- Organizer
  Keystone Symposia
- Place of Presentation
  リノ、米国
- Year and Date
  2011-01-26
- Data Source
  KAKENHI-PROJECT-20590265
[Presentation] Chymase as a useful target to prevent abdominal aortic aneurysm2011
- Author(s)
  Takai S, Jin D, Miyazaki M.
- Organizer
  Keystone Symposia
- Place of Presentation
  リノ、米国
- Year and Date
  2011-01-26
- Data Source
  KAKENHI-PROJECT-21590295
[Presentation] キマーゼ阻害薬による腹部大動脈瘤進展予防の可能性(シンポジウム)2010
- Author(s)
  高井真司、金徳男、宮崎瑞夫
- Organizer
  第38回薬物活性シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-21590295
[Presentation] Combination therapy with angiotensin receptor blocker and T- and L-type calcium channel blocker for attenuation of proteinuria in Dahl-salt sentitive rats.2010
- Author(s)
  高井真司, 金徳男, et al
- Organizer
  23rd Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20590265
[Presentation] キマーゼ阻害薬のターゲット疾患について(シンポジウム)2010
- Author(s)
  高井真司、金徳男、宮崎瑞夫
- Organizer
  第15回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-08-20
- Data Source
  KAKENHI-PROJECT-20590265
[Presentation] キマーゼ阻害薬のターゲット疾患について(シンポジウム)2010
- Author(s)
  高井真司、金徳男、宮崎瑞夫
- Organizer
  第15回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-08-20
- Data Source
  KAKENHI-PROJECT-21590295
[Presentation] Combination therapy with angiotensin receptor blocker and T-and L-type calcium channel blocker for attenuation of proteinuria in Dahl-salt sentitive rats2010
- Author(s)
  Takai S, Jin D, et al.
- Organizer
  23rd Scientific Meeting of the International Society of Hypertension
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-21590295
[Presentation] キマーゼ阻害薬による腹部大動脈瘤進展予防の可能性(シンポジウム)2010
- Author(s)
  高井真司、金徳男、宮崎瑞夫
- Organizer
  第38回薬物活性シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-20590265
[Presentation] キマーゼ阻害薬の開発と臓器保護効果(シンポジウム)2009
- Author(s)
  高井真司、金徳男、宮崎瑞夫
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20590265
[Presentation] マイトマイシン(MMC)包含Gelatin Hydrogelの緑内障濾過手術への応用: MMC単独との比較
- Author(s)
  小嶌祥太、杉山哲也、金　徳男、高井真司、植木麻理、池田恒彦
- Organizer
  第118回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2014-04-02 – 2014-04-06
- Data Source
  KAKENHI-PROJECT-24592684

1. TAKAI Shinji (80288703)

# of Collaborated Projects: 14 results

# of Collaborated Products: 56 results
2. MURAMATSU Michiko (30330096)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. MIYAZAKI Mizuo (10047186)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KOJIMA Shota (10388259)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. SUGIYAMA Tetsuya (20298764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. TATABA Yasuhiko (50211371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 岡本由記子 (10268188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 東野正明 (30397278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KIDA Teruyo

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 石坂信和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 奥英弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 池田恒彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 能崎優太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 衣斐督和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 松本みさき

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Jin Denan 金 徳男

KIN Tokunan 金 徳男

JIN Denan 金 徳男

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Development of artificial blood vessels made from new materials for use in renal dialysis vascular accessPrincipal Investigator

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Searching for the mechanisms and therapeutics in the pathogenesis of stenosis after the implantation of arteriovenous ePTFE artificial and auto blood vessel grafts.Principal Investigator

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Mechanistic and therapeutic investigation of the outside fibroblasts involving the inner neointima formation after implantation of PTFE grafts.Principal Investigator

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Investigation of the mechanisms involving PTFE graft occlusion and searching its pharmacotherapeutics with chymase inhibitorPrincipal Investigator

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Roles of chymase in the development of cardiac remodeling during heart failure progression.Principal Investigator

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Jin Denan 金徳男

KIN Tokunan 金徳男

JIN Denan 金徳男