Takei Kimiko 武居公子

… Alternative Names

TAKEI Kimiko 武居公子

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Researcher Number	90325861
Other IDs
External Links
Affiliation (Current)	2025: 琉球大学, 病院, 助教
Affiliation (based on the past Project Information) *help	2025: 琉球大学, 病院, 助教 2022 – 2023: 琉球大学, 病院, 助教 2011 – 2021: 琉球大学, 医学(系)研究科(研究院), 助教 2010: University of the Ryukyus, 大学院・医学研究科, 助教 2008 – 2010: University of the Ryukyus, 医学研究科, 助教 … More 2008: University of the Ryukyus, 医学研究科, 助教 2007: 国立大学法人琉球大学, 大学院・医学研究科, 助教 2007: University of the Ryukyus, 大学院・医学研究科, 助教 2005 – 2006: 琉球大学, 大学院医学研究科, 助手 2003 – 2004: 琉球大学, 大学院・医学研究科, 助手 2001 – 2002: 琉球大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related / Dermatology Except Principal Investigator Biological Sciences
Keywords	Principal Investigator Rap2 / 有棘細胞癌 / シグナル伝達 / 腫瘍微小環境 / 細胞間接着 / ケラチノサイト / MAPKKKキナーゼ / 癌幹細胞マーカー / 癌幹細胞 / 腫瘍関連マクロファージ … More / 悪性化 / 腫瘍関連マクロファージ(TAM) / TAM / 創傷治癒 / 予後マーカー / マイクロRNA / ケラチン / 転移 / シグナル伝逹 / ゲノム / 癌 / Eカドヘリン / IFN-β / iNOS / ステロイド抵抗性 / 局所免疫 / マクロファージ / Yeast Two-Hybrid法 / 癌抑制遺伝子 / Trc8遺伝子 / TRC8遺伝子 / 皮膚基底細胞腫 … More Except Principal Investigator Rap2 / シグナル伝達 / がん / MAP4K / 極性異常 / 上皮細胞 / がん細胞 / ノックアウトマウス / 癌 / MINK / TNIK / HGK / MAPKKKキナーゼ / TRC8 / 形態形成 / Dexras1 / Rhes / 低分子量GTP結合蛋白質 Less

Cuproptosisによる血管肉腫に対する新規治療戦略Principal Investigator
- Principal Investigator
  
  武居公子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  University of the Ryukyus
腫瘍微小環境におけるRap2の機能解析Principal Investigator
- Principal Investigator
  
  武居公子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  University of the Ryukyus
A search for novel cancer stem cell marker of cutaneous squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  TAKEI KIMIKO
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  University of the Ryukyus
Analysis of Rap2 function in skin wound healingPrincipal Investigator
- Principal Investigator
  
  Takei Kimiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  University of the Ryukyus
A search for candidate genes involved in invasion and metastasis of cutaneous squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  TAKEI Kimiko
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  University of the Ryukyus
Comprehensive survey of microRNAs and mRNAs involved in cutaneous squamous cell carcinoma invasion and metastasisPrincipal Investigator
- Principal Investigator
  
  TAKEI Kimiko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  University of the Ryukyus
Functional analysis of a MAP4K, MINK in adhesion and movement of keratinocytesPrincipal Investigator
- Principal Investigator
  
  TAKEI Kimiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  University of the Ryukyus
低分子量G蛋白質Rap2とがん細胞の分化異常
- Principal Investigator
  
  苅谷研一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of the Ryukyus
低分子量G蛋白質Rap2のエフェクターキナーゼ群とがん細胞の分化異常
- Principal Investigator
  
  苅谷研一
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of the Ryukyus
ケラチノサイトの細胞間接着装置に局在するMAPKKKキナーゼの機能解析Principal Investigator
- Principal Investigator
  
  武居公子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  University of the Ryukyus
マクロファージiNOS遺伝子発現制御におけるステロイド抵抗性機序の解析Principal Investigator
- Principal Investigator
  
  武居公子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  University of the Ryukyus
形態形成シグナル伝達経路の異常による発がん機構の解析
- Principal Investigator
  
  苅谷研一
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of the Ryukyus
Trc8遺伝子(基底細胞腫原因遺伝子Patchedの類縁体)の変異と細胞癌化機構Principal Investigator
- Principal Investigator
  
  武居公子
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  University of the Ryukyus

All 2021 2016 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Phaeohyphomycosis caused by Exophiala jeanselmei in a patient with polymyalgia rheumatica.2010
- Author(s)
  Arakaki, O., Asato, Y., Yagi, N., Taira, K., Yamamoto, Y., Takei, K., Hosokawa, A., Kayo, S., Hagiwara, K., Uezato, H.
- Journal Title
  
  J.Dermatol. 37
  
  Pages: 363-373
- Data Source
  KAKENHI-PROJECT-21791085
[Journal Article] Ectopic coexpression of keratin 8 and 18 promotes invasion of transformed keratinocytes and is induced in patients with cutaneous squamous cell carcinoma.2010
- Author(s)
  Yamashiro, Y., Takei, K., Umikawa, M., Asato, T., Oshiro, M., Uechi, Y., Ishikawa, T., Taira, K., Uezato, H., Kariya, K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 399
  
  Pages: 365-372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791085
[Journal Article] Rap2 function requires palmitoilation and recycling endosome localization2009
- Author(s)
  Uechi, Y., Bayarjargal, M., Umikawa, M., Oshiro, M., Takei, K., Yamashiro, Y., Asato, T., Endo, S., Misaki, R., Taguchi, T., Kariya, K.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 378
  
  Pages: 732-737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790794
[Journal Article] MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC12008
- Author(s)
  Nonaka H/Takei K (co-1st), et.al.
- Journal Title
  
  Biochemical and Biophysical Research Communications 377
  
  Pages: 573-578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790794
[Journal Article] MINK is a Rap2 effector for phosphorylation of the postosynaptic scaffold protein TANC12008
- Author(s)
  Nonaka,H., Takei,K., Umikawa,M., Oshiro M., Kuninaka, K., Bayarjargal, M., Asato, T., Yamashiro, Y., Uechi, Y., Endo, S., Suzuki, T., Kariya, K.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 377
  
  Pages: 573-578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790794
[Presentation] Functional analysis of Rap2 in tumor microenvironment2021
- Author(s)
  Kimiko Takei, Masato Umikawa, Tsuyoshi Asato, Ken-ichi Kariya
- Organizer
  The 46th Annual Meeting of the Japanese Society for Investigative Dermatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08273
[Presentation] Roles of Rap2 signaling in cutaneous function2016
- Author(s)
  Kimiko Takei, Tsuyoshi Asato, Masato Umikawa, Minoru Oshiro, Ken-ichi Kariya
- Organizer
  日本研究皮膚科学会年次総会　第41回年次学術大会・総会
- Place of Presentation
  宮城県仙台市仙台国際センター
- Year and Date
  2016-12-09
- Data Source
  KAKENHI-PROJECT-15K09775
[Presentation] A search for candidate genes involved in invasion and metastasis of cutaneous squamous cell carcinoma.2011
- Author(s)
  Kimiko Takei, Yoshito Yamashiro, Masato Umikawa, Tsuyoshi Asato, Minoru Oshiro, Yukiko Uechi, Kiyohito Taira, Ken-ichi Kariya and Hiroshi Uezato
- Organizer
  日本研究皮膚科学会　第36回年次学術大会・総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591624
[Presentation] The proteomic search for prognosis markers of cutaneous squamous cell carcinoma.2009
- Author(s)
  Yoshito Yamashiro(代表発表者), Kimiko Takei, Masato Umikawa, Tsuyoshi Asato, Kiyohito Taira, Hiroshi Uezato, Ken-ichi Kariya
- Organizer
  MBSJ2009(第32回日本分子生物学会年会)プログラム:3P-0743:418
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21791085
[Presentation] Localization of Rap2 in recycling endosome in a palmitoylation-dependent manner.2008
- Author(s)
  Maitsetseg Bayarjargal(代表発表者), Yukiko Uechi, Shogo Endo, Kimiko Nonaka-Takei, Minoru Oshiro, Masato Umikawa, Tsuyoshi Asato, Yoshito Yamashiro, Tomohiko Taguchi, Ken-ichi Kariya
- Organizer
  Biochemistry Molecular Biology(BMB)2008(第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)プログラム:1P-0444:219
- Place of Presentation
  神戸国際展示場
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-21791085

1. 海川正人 (00325838)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
2. 苅谷研一 (40263371)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. UEZATO Hiroshi (10137721)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 丸山一郎 (70426568)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. INAMINE Morihiko (90437989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 遠藤昌吾 (60192514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Takei Kimiko 武居 公子

TAKEI Kimiko 武居 公子

Research Projects

Research Products

Co-Researchers

Cuproptosisによる血管肉腫に対する新規治療戦略Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腫瘍微小環境におけるRap2の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A search for novel cancer stem cell marker of cutaneous squamous cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of Rap2 function in skin wound healingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A search for candidate genes involved in invasion and metastasis of cutaneous squamous cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive survey of microRNAs and mRNAs involved in cutaneous squamous cell carcinoma invasion and metastasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of a MAP4K, MINK in adhesion and movement of keratinocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

低分子量G蛋白質Rap2とがん細胞の分化異常

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

低分子量G蛋白質Rap2のエフェクターキナーゼ群とがん細胞の分化異常

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ケラチノサイトの細胞間接着装置に局在するMAPKKKキナーゼの機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マクロファージiNOS遺伝子発現制御におけるステロイド抵抗性機序の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

形態形成シグナル伝達経路の異常による発がん機構の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Trc8遺伝子(基底細胞腫原因遺伝子Patchedの類縁体)の変異と細胞癌化機構Principal Investigator

Principal Investigator

Project Period (FY)

Takei Kimiko 武居公子

TAKEI Kimiko 武居公子