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ZHAO Wei-Hua  趙 維華

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ZHAO Wei-hua  趙 維華

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Researcher Number 90327916
Other IDs
Affiliation (based on the past Project Information) *help 2012 – 2014: 昭和大学, 医学部, 講師
2007 – 2008: 昭和大学, 医学部, 講師
2001: Showa University, School of Medicine, Department of Microbiology and Immunology, Assistant, 医学部, 助手
Review Section/Research Field
Principal Investigator
Infectious disease medicine
Except Principal Investigator
Bacteriology (including Mycology) / 膠原病・アレルギー・感染症内科学
Keywords
Principal Investigator
メタロ-β-ラクタマーゼ / β-ラクタム剤 / インテグロン-1 / 耐性遺伝子 / 分子疫学 / 薬剤耐性グラム陰性菌 / DNAシークエンス解析 / PCR分析 / メタロ-β-ラクタマーゼ (MBL) / β-ラクタマーゼ / インテグロン / 薬剤耐性遺伝子 / グラム陰性桿菌 … More
Except Principal Investigator
… More HIV / MRSA / Salmonella / Helicobacter pylori / Combination effect / Antibiotics / Antimicrobial / Catechin / 抗ウイルス / VREF / サルモネラ / ヘリコバクター / 併用効果 / 抗生物質 / 抗菌 / カテキン / PCRアレイ / DNAマイクロアレイ / IL-4 / サイトカイン / マイクロアレイ / アポトーシス誘導因子 / マスト細胞 Less
  • Research Projects

    (3 results)
  • Research Products

    (36 results)
  • Co-Researchers

    (5 People)
  •  Integrons as epidemiological molecular markers for identifying and surveying multi-drug resistance genes in Gram-negative bacilliPrincipal Investigator

    • Principal Investigator
      ZHAO Wei-Hua
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Infectious disease medicine
    • Research Institution
      Showa University
  •  Identification and Cloning of an Apoptosis-Inducing Factor of Mast Cells by DNA Microarray Analysis

    • Principal Investigator
      HU Zhi-qing
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Showa University
  •  Antimicrobial activities of catechin, catechin-antibiotic combinations and mechanisms

    • Principal Investigator
      SHIMAMURA Tadakatsu
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Showa University

All 2015 2014 2013 2012 2008 2007 2003 2002 2001 Other

All Journal Article Presentation Book

  • [Book] Chapter XI. What can be learned from the discrepant results in mast cell research? Mast Cells : Roles(Monograph, Nova Science Publishers, NY, USA)2008

    • Author(s)
      Zhi-Qing Hu, Wei-Hua Zhao and Tadakatsu Shimamura
    • Publisher
      Interactions and Disorders
    • Data Source
      KAKENHI-PROJECT-19591182
  • [Book] Mast Cells : Roles, Interactions and Disorders、Chapter XI2008

    • Author(s)
      Zhi-Qing Hu, Wei-Hua Zhao, Tadakatsu Shimamura
    • Total Pages
      11
    • Publisher
      Nova Science Publishers, NY, USA
    • Data Source
      KAKENHI-PROJECT-19591182
  • [Book] Chapter VI. Regulation of mast cell development and apoptosis by Th1 and Th2 cytokines (Monograph, Nova Science Publishers, NY, USA)2007

    • Author(s)
      Zhi-Qing Hu, Wei-Hua Zhao and Tadakatsu Shimamura
    • Publisher
      New Cell Differentiation Research Topics
    • Data Source
      KAKENHI-PROJECT-19591182
  • [Journal Article] Acquired metallo-β-lactamases and their genetic association with class 1 integrons and ISCR elements in Gram-negative bacteria2015

    • Author(s)
      Wei-Hua Zhao and Zhi-Qing Hu
    • Journal Title

      Future Microbiology

      Volume: 10(5)

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591489
  • [Journal Article] Integrons: epidemiological molecular markers for identifying and surveying metallo-β-lactamase genes in Gram-negative bacilli2014

    • Author(s)
      Wei-Hua Zhao and Zhi-Qing Hu
    • Journal Title

      Future Microbiology

      Volume: 9 Issue: 1 Pages: 5-8

    • DOI

      10.2217/fmb.13.21

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591489
  • [Journal Article] Type 1 interferon-associated necroptosis: a novel mechanism for Salmonella enterica Typhimurium to induce macrophage death2013

    • Author(s)
      Zhi-Qing Hu and Wei-Hua Zhao
    • Journal Title

      Cellular & Molecular Immunology

      Volume: 10 Issue: 1 Pages: 10-12

    • DOI

      10.1038/cmi.2012.54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591489
  • [Journal Article] Epidemiology and genetics of CTX-M extended-spectrum β-lactamases in Gram-negative bacteria2013

    • Author(s)
      Wei-Hua Zhao and Zhi-Qing Hu
    • Journal Title

      Critical Reviews in Microbiology

      Volume: 39 Issue: 1 Pages: 79-101

    • DOI

      10.3109/1040841x.2012.691460

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591489
  • [Journal Article] Critical role of PD-1/PD-L1 pathway in generation and function of follicular regulatory T cells2013

    • Author(s)
      Zhi-Qing Hu and Wei-Hua Zhao
    • Journal Title

      Cellular & Molecular Immunology

      Volume: 10 Issue: 4 Pages: 286-288

    • DOI

      10.1038/cmi.2013.15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591489
  • [Journal Article] Identification of a plasmid-borne blaIMP-11 gene in clinical isolates of Escherichia coli and Klebsiella pneumoniae2012

    • Author(s)
      Wei-Hua Zhao, Gelin Chen, Ribu Ito, Satoshi Kimura and Zhi-Qing Hu
    • Journal Title

      Journal of Medical Microbiology

      Volume: 61 Issue: 2 Pages: 246-251

    • DOI

      10.1099/jmm.0.035626-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591489
  • [Journal Article] Acinetobacter: a potential reservoir and dispenser for β-lactamases2012

    • Author(s)
      Wei-Hua Zhao and Zhi-Qing Hu
    • Journal Title

      Critical Reviews in Microbiology

      Volume: 38 Issue: 1 Pages: 30-51

    • DOI

      10.3109/1040841x.2011.621064

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591489
  • [Journal Article] Novel insights into the molecular mechanisms of α-fetoprotein expression and malignant phenotypes of hepatocellular carcinoma2012

    • Author(s)
      Zhi-Qing Hu and Wei-Hua Zhao
    • Journal Title

      Cellular & Molecular Immunology

      Volume: 9 Issue: 1 Pages: 7-8

    • DOI

      10.1038/cmi.2011.30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591489
  • [Journal Article] Up-regulation of IL-33 expression in various types of murine cells by IL-3 and IL-42012

    • Author(s)
      Zhi-Qing Hu and Wei-Hua Zhao
    • Journal Title

      Cytokine

      Volume: 58 Issue: 2 Pages: 267-73

    • DOI

      10.1016/j.cyto.2012.01.019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591489
  • [Journal Article] What can be learned from the discrepant results in mast cell research?(Review)2008

    • Author(s)
      Hu Z-Q, Zhao W-H, Shimamura T
    • Journal Title

      Mast Cells:Roles, Interactions and Disorders Monograph

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591182
  • [Journal Article] Regulation of mast cell development and apoptosis by Th1 and Th2 cytokines(Review)2008

    • Author(s)
      Hu Z-Q, Zhao W-H, Shimamura T
    • Journal Title

      New Cell Differentiation Research Topics Monograph

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591182
  • [Journal Article] Mechanism of interleukin-4-triggered mast cell apoptosis2007

    • Author(s)
      Zhi-Qing Hu, Wei-Hua Zhao and Tadakatsu Shimamura
    • Journal Title

      International Conference on Immunology

    • Data Source
      KAKENHI-PROJECT-19591182
  • [Journal Article] Regulation of mast cell development by inflammatory factors2007

    • Author(s)
      Zhi-Qing Hu, Wei-Hua Zhao and Tadakatsu Shimamura
    • Journal Title

      Current Medicinal Chemistry 14

      Pages: 3044-3050

    • Data Source
      KAKENHI-PROJECT-19591182
  • [Journal Article] Regulation of mast cell development by inflammatory factors(Review)2007

    • Author(s)
      Hu Z-Q, Zhao W-H, Shimamura T
    • Journal Title

      Current Medicinal Chemistry 14(28)

      Pages: 3044-3050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591182
  • [Journal Article] Restoration of antibacterial activity of β-lactams by epigallocatechin gallate against (3-lactamase-producing species depending on location of β-lactamase2003

    • Author(s)
      Zhao W-H, Asano N, Hu Z-Q, Shimamura T
    • Journal Title

      Journal of Pharmacy and Pharmacology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11470071
  • [Journal Article] Restoration of antibacterial activity of β-lactams by epigallocatechin...2003

    • Author(s)
      Zhao W-H, Shimamura T. et al.
    • Journal Title

      Journal of Pharmacy and Pharmacology (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11470071
  • [Journal Article] Inhibition of penicillinase by epigallocatechin gallate resulting in...2002

    • Author(s)
      Zhao W-H, Shimamura T. et al.
    • Journal Title

      Antimicrobial Agents and Chemotherapy 46・

      Pages: 2266-2268

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11470071
  • [Journal Article] Inhibition of penicillinase by epigallocatechin gallate resulting in restoration of antibacterial activity of penicillin against penicillinase-producing Staphylococcus aureus2002

    • Author(s)
      Zhao W-H, Hu Z-Q, Hara Y, Shimamura T
    • Journal Title

      Antimicrobial Agents and Chemotherapy 46

      Pages: 2266-2268

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11470071
  • [Journal Article] Epigallocatechin gallate synergistically enhances the activity of carbapenems against methicillin-resistant Staphylococcus aureus2002

    • Author(s)
      Hu Z-Q, Zhao W-H, Asano N, Yoda Y, Hara Y, Shimamura T
    • Journal Title

      Antimicrobial Agents and Chemotherapy 46

      Pages: 558-560

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11470071
  • [Journal Article] Additive, indifferent and antagonistic effects in combinations of epigallocatechin gallate with 12 non-β-lactam antibiotics against methicillin-resistant Staphylococcus aureus2002

    • Author(s)
      Hu Z-Q, Zhao W-H, Yoda Y, Asano N, Hara Y, Shimamura T
    • Journal Title

      Journal of Antimicrobial and Chemotherapy 50

      Pages: 1051-1054

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11470071
  • [Journal Article] Mechanism of synergy between epigallocatechin gallate and β-lactams against methicillin-resistant Staphylococcus aureus2001

    • Author(s)
      Zhao W-H, Hu Z-Q, Okubo S, Hara Y, Shimamura T
    • Journal Title

      Antimicrobial Agents and Chemotherapy 45

      Pages: 1737-1742

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11470071
  • [Journal Article] Inhibition by epigallocatechin gallate (EGCg) of conjugative R...2001

    • Author(s)
      Zhao W-H, Shimamura T. et al.
    • Journal Title

      Journal of Infection and Chemotherapy 7・

      Pages: 195-197

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11470071
  • [Journal Article] Inhibition by epigallocatechin gallate (EGCg) of conjugative R plasmid transfer in Escherichia coli2001

    • Author(s)
      Zhao W-H, Hu Z-Q, Hara Y, Shimamura T
    • Journal Title

      Journal of Infection and Chemotherapy 7

      Pages: 195-197

    • NAID

      50000964512

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11470071
  • [Journal Article] Mechanism of synergy between epigallocatechin gallate and β-lactams...2001

    • Author(s)
      Zhao W-H, Shimamura T. et al.
    • Journal Title

      Antimicrobial Agents and Chemotherapy 45・

      Pages: 1737-1742

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11470071
  • [Journal Article] Epigallocatechin gallate synergy with ampicillin-sulbactam against 28 clinical isolates of methicillin-resistant Staphylococcus aureus2001

    • Author(s)
      Hu Z-Q, Zhao W-H, Hara Y, Shimamura T
    • Journal Title

      Journal of Antimicrobial and Chemotherapy 48

      Pages: 361-364

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11470071
  • [Presentation] Spread of integron-associated multidrug resistance in bacilli2014

    • Author(s)
      Wei-Hua Zhao and Zhi-Qing Hu
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      千葉 (タワーホール船堀)
    • Data Source
      KAKENHI-PROJECT-24591489
  • [Presentation] Up-regulation by IL-4, IL-13, FGF-b and down-regulation by TGF-β of IL-33 expression in vascular endothelial cells2012

    • Author(s)
      Zhi-Qing Hu and Wei-Hua Zhao
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24591489
  • [Presentation] Colonization of intI1-blaIMP-1-aac(6’)IIc-qacEΔ1 carried by a conjugative plasmid in Enterobacteriaceae.2012

    • Author(s)
      Wei-Hua Zhao and Zhi-Qing Hu
    • Organizer
      13th Asia-Pacific Congress of Clinical Microbiology and Infection
    • Place of Presentation
      Beijing
    • Data Source
      KAKENHI-PROJECT-24591489
  • [Presentation] Promotion of SCF-dependent survival and proliferation of mouse mast cells by IL-12 p702007

    • Author(s)
      Wei-Hua Zhao, Zhi-Qing Hu and Tadakatsu Shimamura
    • Organizer
      International Conference on Immunology
    • Place of Presentation
      Shanghai
    • Data Source
      KAKENHI-PROJECT-19591182
  • [Presentation] Mechanism of interleukin-4-triggered mast cell apoptosis2007

    • Author(s)
      Zhi-Qing Hu, Wei-Hua Zhao and Tadakatsu Shimamura
    • Organizer
      International Conference on Immunology
    • Place of Presentation
      Shanghai
    • Data Source
      KAKENHI-PROJECT-19591182
  • [Presentation] Mechanism of interleukin-4-triggered mast cell apoptosis2007

    • Author(s)
      Hu Z-Q, Zhao W-H, Shimamura T
    • Organizer
      International Conference on Immunology
    • Place of Presentation
      Shanghai,China
    • Year and Date
      2007-07-14
    • Data Source
      KAKENHI-PROJECT-19591182
  • [Presentation] Acquired metallo-β-lactamases and their genetic supports in clinical isolates of Gram-negative bacilli

    • Author(s)
      Wei-Hua Zhao and Zhi-Qing Hu
    • Organizer
      15th APCCMI (Asia Pacific Congress on Clinical Microbiology & Infection)
    • Place of Presentation
      Kuala Lumpur, Malaysia
    • Year and Date
      2014-11-26 – 2014-11-29
    • Data Source
      KAKENHI-PROJECT-24591489
  • [Presentation] IL-33 expression in vascular endothelial cells is up-regulated by IL-4, IL-13, FGF-b and down-regulated by TGF-β

    • Author(s)
      Wei-Hua Zhao and Zhi-Qing Hu.
    • Organizer
      The 1st Nature Immunology and Cellular & Molecular Immunology Joint Conference
    • Place of Presentation
      Hefei, China
    • Year and Date
      2015-06-17 – 2015-06-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591489
  • 1.  HU Zhi-qing (60245826)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 32 results
  • 2.  SHIMAMURA Tadakatsu (50056149)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 3.  OKUBO Sachie (40053938)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  YANAGAWA Yoko (20307044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  YAMAGUCHI Koushi (70210359)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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