Saito Ryota 齋藤良太

… Alternative Names

齋藤良太サイトウリヨウタ

SAITO Ryota 齋藤良太

Less

Researcher Number	90327974
Other IDs
External Links
Affiliation (Current)	2025: 東邦大学, 理学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2022: 東邦大学, 理学部, 教授 2013 – 2015: 東邦大学, 理学部, 准教授 2005: 東京農工大学, 大学院・工学研究部, 特任助手 2003 – 2004: 成蹊大学, 工学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 37010:Bio-related chemistry / Bio-related chemistry / Reaction engineering/Process system Except Principal Investigator Chemistry related to living body
Keywords	Principal Investigator プテリン / リボソーム不活性化タンパク質阻害剤 / リシン / 毒素タンパク質 / リボソーム不活性化タンパク質 / リシン毒素A鎖 / 阻害剤 / リシン毒素 / X線結晶構造解析 / リシン毒素A鎖阻害剤 … More / pterin-7-carboxamide / 構造活性相関 / 糖尿病合併症治療薬 / GFP発色団モデル / ピラジン / ドッキングスタディ / アルドース還元酵素阻害剤 / フッ素 / 光増感不斉極性付加 / アルコール / 1,1-ジッフェニルプロペン / フッ素含有キラル増感剤 / ベンゼンテトラカルボン酸エステル / シクロオクテン / 不斉光増感反応 / 圧力効果 / エントロピー / 光不斉反応 / 超臨界二酸化炭素 … More Except Principal Investigator Superoxide radical anion / Imidazopyrazine / Fluorescence derivatization reagent / Fluorescent probe / Static quenching / PH sensing / Ouinoxaline / Fluorescent bidentate ligand / 蛍光のON-OFF / 3-ヒドロキシピリドン / 蛍光プロープ / 鉄錯体 / カテコール / 3-ヒドロキシ-4(1H)-ピリジノン / スーパーオキシドラジカルアニオン / イミダゾピラジン / 蛍光誘導体化試薬 / 蛍光プローブ / 静的消光 / pHセンシング / キノキサリン / 蛍光性2座配位子 Less

Development of powerful ad exhaustive inhibitors for ribosome-inactivating proteinsPrincipal Investigator
- Principal Investigator
  
  Saito Ryota
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Toho University
Development of new types of aldose reductase inhibitors based on the structure of the target enzymePrincipal Investigator
- Principal Investigator
  
  SAITO Ryota
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Toho University
超臨界二酸化炭素の溶媒特性を利用した光不斉反応の制御研究Principal Investigator
- Principal Investigator
  
  齋藤良太
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Reaction engineering/Process system
- Research Institution
  Tokyo University of Agriculture and Technology
  Seikei University
Studies on Novel Syntheses of Fluorecent Tripodal Hexadentate Iigands and Than Application to fluorescent Probes for Microscopic Observation of Cells
- Principal Investigator
  
  KATOH Akira
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Seikei University

All 2023 2022 2021 2020 2016 2015 2014 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Differential DNA-binding and cofactor recruitment are possible determinants of the synthetic steroid YK11-dependent gene expression by androgen receptor in breast cancer MDA-MB 453?cells2022
- Author(s)
  Kanno Yuichiro、Saito Nao、Saito Ryota、Kosuge Tomohiro、Shizu Ryota、Yatsu Tomofumi、Hosaka Takuomi、Nemoto Kiyomitsu、Kato Keisuke、Yoshinari Kouichi
- Journal Title
  
  Experimental Cell Research
  
  Volume: 419 Issue: 2 Pages: 113333-113333
- DOI
  10.1016/j.yexcr.2022.113333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K18202, KAKENHI-PROJECT-19K05699
[Journal Article] Pterin-based small molecule inhibitor capable of binding to the secondary pocket in the active site of ricin-toxin A chain2022
- Author(s)
  Saito Ryota、Goto Masaru、Katakura Shun、Ohba Taro、Kawata Rena、Nagatsu Kazuki、Higashi Shoko、Kurisu Kaede、Matsumoto Kaori、Ohtsuka Kouta
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 12 Pages: 1-13
- DOI
  10.1371/journal.pone.0277770
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05699
[Journal Article] Conformational change in ricin toxin A-Chain: A critical factor for inhibitor binding to the secondary pocket2022
- Author(s)
  Goto Masaru、Higashi Shoko、Ohba Taro、Kawata Rena、Nagatsu Kazuki、Suzuki Saori、Anslyn Eric V.、Saito Ryota
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 627 Pages: 1-4
- DOI
  10.1016/j.bbrc.2022.08.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05699
[Journal Article] Unusual Temperature Dependence of Enantioselectivity in Asymmetric Reductions by Chiral NADH Models2006
- Author(s)
  Ryota Saito, Shoichiro Naruse, Koji Takano, Keiko Fukuda, Akira Katoh, Yoshihisa Inoue
- Journal Title
  
  Organic Letters (in press)
- Data Source
  KAKENHI-PROJECT-15760572
[Journal Article] High-Performance Liquid Chromatographic Enantio-Separation Based on Diastereomer Formation with New Fluorescent Chiral Quinoxaline2005
- Author(s)
  Akira Katoh, Ryoji Yamamoto, Takeshi Fujimoto, Ryota Saito
- Journal Title
  
  Heterocycles 65-5
  
  Pages: 1111-1120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15550152
[Journal Article] Studies on the Chemiluminescence Mechanism of Cypridina Luciferin Analogues : Dissociation Constants of Singlet-Excited Cypridina Oxyluciferin Analogues2004
- Author(s)
  齋藤良太
- Journal Title
  
  Abstracts of the 13^<th> International Symposium on Bioluminescence and Chemiluminescence
  
  Pages: 148-148
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15550152
[Journal Article] Well-Divided and pH-Dependent Bimodal Chemiluminescence of 6-phenyl-8-(4-substd, phenyl)imidazo[1.2-a]pyrazin-3(7H)-ones Induced by Superoxide Anion2004
- Author(s)
  齋藤良太
- Journal Title
  
  Heterocycles 63・4
  
  Pages: 759-764
- Data Source
  KAKENHI-PROJECT-15550152
[Journal Article] 2-アセチルアミノ-5-アリールピラジン類の蛍光特性2004
- Author(s)
  齋藤良太
- Journal Title
  
  第34回複素環化学討論会講演要旨集 20-05
  
  Pages: 183-184
- Data Source
  KAKENHI-PROJECT-15550152
[Journal Article] Synthesis of 6-(2', 3'-dihydroxybenzyl)amino-2, 3-dimorpholinoquinoxaline And Fluorescent Characteristic of Its Metal Complex2004
- Author(s)
  Akira Katoh, Keita Matsui, Ryota Saito
- Journal Title
  
  Abstracts 11 for 84^<th> Spring Meeting of the Chemical Society of Japan
  
  Pages: 1322-1322
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15550152
[Journal Article] Synthesis of Aime type Heterocyclic Compounds and Their Conversion into Functional Molecules2004
- Author(s)
  Akira Katoh, Ryota Saito
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan 62-4
  
  Pages: 335-346
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15550152
[Journal Article] Enantiodifferentiating Photoaddition of Alcohols to 1,1-Diphenylpropene in Supercritical Carbon Dioxide : Sudden Jump of Optical Yield at the Critical Density2004
- Author(s)
  Yasuhiro Nishiyama, Masayuki Kaneda, Ryota Saito, Tadashi Mori, Takehiko Wada, Yoshihisa Inoue
- Journal Title
  
  Journal of the American Chemical Society 126巻21号
  
  Pages: 6568-6569
- Data Source
  KAKENHI-PROJECT-15760572
[Journal Article] Studies on the Chemiluminescence Mechanism of Cypridina Luciferin Analogues : Dissociation Constants of Sigalet-Excited Cypridina Oxyluciferin Analogues2004
- Author(s)
  齋藤良太
- Journal Title
  
  Luminescence, J.Biol.& Chem.Luminescence 19・3
  
  Pages: 148-148
- Data Source
  KAKENHI-PROJECT-15550152
[Journal Article] 6,8-Diarylimidazo[1,2-a]pyrazin-3(7H)-ones as Potential Chemiluminescent pH/Su peroxide Double Sensors2004
- Author(s)
  齋藤良太
- Journal Title
  
  Abstracts of the 13^<th> International Symposium on Bioluminescence and Chemiluminescence
  
  Pages: 172-172
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15550152
[Journal Article] Studies on the Chemiluminescence Mechanism of Cypridina Luciferin Analogues: Dissociation Constants of Singlet-Excited Cypridina Oxyluciferin Analogues2004
- Author(s)
  Ryota Saito, Eriko Iwasa, Akira Katoh
- Journal Title
  
  Abstracts of the 13^<th> International Symposium on Bioluminescence and Chemiluminescence
  
  Pages: 148-148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15550152
[Journal Article] 6,8-Diarylimidazo[1,2-1]pyrazin-3(7H)-ones as Potential Chemiluminescent pH/Superoxide Double Sensors2004
- Author(s)
  齋藤良太
- Journal Title
  
  Luminescence, J.Biol.& Chem.Luminescence 19・3
  
  Pages: 172-172
- Data Source
  KAKENHI-PROJECT-15550152
[Journal Article] Well Divided and pH-dependent Bimodal Chemiluminescence of 2-Methyl-6-phenyl-8-(4-substituted phenyl)imidazo[1,2-a]pyrazin-3(7H)-ones Induced by O_22004
- Author(s)
  齋藤良太
- Journal Title
  
  Heterocycles 63
  
  Pages: 759-764
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15550152
[Journal Article] Well Divided and pH-Dependent Bimodal Chemiluminescence of 2-Methyl-6-phenyl-8-(4-substituted phenyl)imidazo[1,2-a]pyrazin-3(7H)-ones Induced by Superoxide Anion2004
- Author(s)
  Ryota Saito, Chizuru Inoue, Akira Katoh
- Journal Title
  
  Heterocycles 63-4
  
  Pages: 759-764
- NAID
  40006266612
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15550152
[Journal Article] 6, 8-Diarylimidazo[1, 2-a]pyrazin-3(7H)-ones as Potential Chemiluminescent pH/Superoxide Double Sensors2004
- Author(s)
  Ryota Saito, Naoko suga, Akira Katoh, Shoji Maki, Takashi Hirano, Haruki Niwa
- Journal Title
  
  Abstracts of the 13^<th> International Symposium on Bioluminescence and Chemiluminescence
  
  Pages: 172-172
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15550152
[Presentation] リシン毒素A鎖のコンフォーメーション変化：活性部位に隣接する二次ポケットへの阻害剤取込みを可能にする重要因子2023
- Author(s)
  後藤勝・河田麗菜・永津和輝・片倉駿・栗栖楓・東翔子・齋藤良太
- Organizer
  第20回ホスト-ゲスト・超分子化学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K05699
[Presentation] 2位をアリールスルホニル基及びアリールスルフィニル基で修飾した Botryllazine B 類縁体の合成とアルドース還元酵素阻害活性2023
- Author(s)
  白井祐生・後藤勝・齋藤良太
- Organizer
  第103日本化学会春季年会
- Data Source
  KAKENHI-PROJECT-19K05699
[Presentation] 2位に水素結合性アロイル基を導入した Botryllazine B類の合成とアルドース還元酵素阻害活性2023
- Author(s)
  川田純奈・後藤勝・齋藤良太
- Organizer
  第103日本化学会春季年会
- Data Source
  KAKENHI-PROJECT-19K05699
[Presentation] 4位及び4,5位にアルキル基を有する新規3-ヒドロキシチアゾール-2(3H)チオン類及びそれらの亜鉛錯体の合成とインスリン様活性2022
- Author(s)
  大庭麟太郎・吉川豊・内藤行喜・安井裕之・齋藤良太
- Organizer
  第51回複素環化学討論会
- Data Source
  KAKENHI-PROJECT-19K05699
[Presentation] Botryllazine B誘導体のアルドース還元酵素阻害に関する構造活性相関: 2-ベンゾイル基上の置換基効果2022
- Author(s)
  川田純奈・後藤勝・齋藤良太
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-19K05699
[Presentation] リシンAサブユニット新規阻害剤の結合メカニズム2021
- Author(s)
  大庭太郎・栗栖楓・坂本奈津美・東翔子・齋藤良太・後藤勝
- Organizer
  2021年度日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-19K05699
[Presentation] フタルイミドで修飾したアミノ酸残基を末端に有するトリペプチド含有プテリン誘導体のリシン毒素 A 鎖阻害能評価2021
- Author(s)
  栗栖楓・坂本奈津美・東翔子・後藤勝・齋藤良太
- Organizer
  第50回複素環化学討論会
- Data Source
  KAKENHI-PROJECT-19K05699
[Presentation] トリペプチド側鎖を有する新規プテリン-7-カルボキサミド類の合成とリシン毒素A鎖阻害活性評価2020
- Author(s)
  片倉駿, 東翔子, 後藤勝, 齋藤良太
- Organizer
  第10回CSJ化学フェスタ
- Data Source
  KAKENHI-PROJECT-19K05699
[Presentation] アルドース還元酵素阻害活性を有するbotryllazine B類似体の合成と構造活性相関2016
- Author(s)
  加藤彰大・大菅由依・佐々木要・小松俊哉・齋藤良太
- Organizer
  第71回有機合成化学協会関東支部シンポジウム
- Place of Presentation
  東京農工大学（東京都小金井市）
- Year and Date
  2016-05-14
- Data Source
  KAKENHI-PROJECT-25410179
[Presentation] Synthesis and aldose reductase inhibitory activity of botryllazine B analogues having bicyclic heterocycles on the C6 position: A structure-activity relationship study2015
- Author(s)
  Saito, Ryota; Katoh, Akihiro; Hitotsumatsu, Kumiko; Sasaki, Kaname Komatsu, Toshiya
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015
- Place of Presentation
  ホノルル（アメリカ合衆国）
- Year and Date
  2015-12-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410179
[Presentation] プテリン-7-カルボキサミド類の合成とアルドース還元酵素阻害活性2014
- Author(s)
  鈴木沙織, 佐々木要, 齋藤良太
- Organizer
  第44回複素環化学討論会
- Place of Presentation
  札幌市民ホール（北海道・札幌市）
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PROJECT-25410179
[Presentation] プテリン-7-カルボキサミド類の簡易合成とそれらのリシン毒素A鎖阻害活性2014
- Author(s)
  齋藤良太, J. M. Pruet, L. A. Manzano, A. F. Monzingo, E. V. Anslyn, J. D. Robertus
- Organizer
  第44回複素環化学討論会
- Place of Presentation
  札幌市民ホール（北海道・札幌市）
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-25410179
[Presentation] Highly potent aldose reductase inhibitors derived from botryllazine B
- Author(s)
  Ryota Saito, Mai Tokita, Kumiko Hitotsumatsu, Chikako Ishikawa, Toshiya Komatsu
- Organizer
  247th American Chemical Society National Meeting & Exposition
- Place of Presentation
  Dallas, TX, USA
- Data Source
  KAKENHI-PROJECT-25410179

1. KATOH Akira (00167339)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 井上佳久 (30112543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 後藤勝 (80379289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. 齋藤菜緒

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Saito Ryota 齋藤 良太

齋藤 良太 サイトウ リヨウタ

SAITO Ryota 齋藤 良太

Research Projects

Research Products

Co-Researchers

Development of powerful ad exhaustive inhibitors for ribosome-inactivating proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new types of aldose reductase inhibitors based on the structure of the target enzymePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

超臨界二酸化炭素の溶媒特性を利用した光不斉反応の制御研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on Novel Syntheses of Fluorecent Tripodal Hexadentate Iigands and Than Application to fluorescent Probes for Microscopic Observation of Cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Differential DNA-binding and cofactor recruitment are possible determinants of the synthetic steroid YK11-dependent gene expression by androgen receptor in breast cancer MDA-MB 453?cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pterin-based small molecule inhibitor capable of binding to the secondary pocket in the active site of ricin-toxin A chain2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Conformational change in ricin toxin A-Chain: A critical factor for inhibitor binding to the secondary pocket2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unusual Temperature Dependence of Enantioselectivity in Asymmetric Reductions by Chiral NADH Models2006

Author(s)

Journal Title

Data Source

[Journal Article] High-Performance Liquid Chromatographic Enantio-Separation Based on Diastereomer Formation with New Fluorescent Chiral Quinoxaline2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Studies on the Chemiluminescence Mechanism of Cypridina Luciferin Analogues : Dissociation Constants of Singlet-Excited Cypridina Oxyluciferin Analogues2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Well-Divided and pH-Dependent Bimodal Chemiluminescence of 6-phenyl-8-(4-substd, phenyl)imidazo[1.2-a]pyrazin-3(7H)-ones Induced by Superoxide Anion2004

Author(s)

Journal Title

Data Source

[Journal Article] 2-アセチルアミノ-5-アリールピラジン類の蛍光特性2004

Author(s)

Journal Title

Data Source

[Journal Article] Synthesis of 6-(2', 3'-dihydroxybenzyl)amino-2, 3-dimorpholinoquinoxaline And Fluorescent Characteristic of Its Metal Complex2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Synthesis of Aime type Heterocyclic Compounds and Their Conversion into Functional Molecules2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Enantiodifferentiating Photoaddition of Alcohols to 1,1-Diphenylpropene in Supercritical Carbon Dioxide : Sudden Jump of Optical Yield at the Critical Density2004

Author(s)

Journal Title

Saito Ryota 齋藤良太

齋藤良太サイトウリヨウタ

SAITO Ryota 齋藤良太