LI Wei 李巍

Researcher Number	90328633
Other IDs	https://orcid.org/0000-0003-4143-8597
Affiliation (Current)	2025: 東邦大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 東邦大学, 薬学部, 教授 2011 – 2020: 東邦大学, 薬学部, 准教授 2008: Toho University, 薬学部, 准教授 2006 – 2007: 東邦大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related / Natural medicines / Chemical pharmacy / Environmental pharmacy Except Principal Investigator Natural medicines / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Chemical pharmacy
Keywords	Principal Investigator ジンチョウゲ科 / ジテルペノイド / ダフナン / チグリアン / HIV / 天然物化学 / トウダイグサ科 / 抗HIV活性 / 薬学 / 創薬 … More / 天然物 / 構造解析プログラム / 構造同定 / LC-MS / 生薬 / Shock & Kill / Shock ＆ Kill / HIV潜伏感染再活性化剤 / ダフナン型ジテルペノイド / 創薬シーズ探索 / 瑞香狼毒 / 甘遂 / ミツマタ / ジンチョウゲ / 抗HIV / ダフナン型 / 構造活性相関 / gnidimacrin / 抗HIV薬 / Gnidimacrin / HIV感染症 / 漢方薬 / プロテインチロシンホスファターゼ1B / 糖尿病 / プロテインチロシンホスファターゼ1B阻害剤 / サポニン / 膵リパーゼ / acanthopanaxoside / 果実 / エゾウコギ / 剌五加 / 芳香族化合物 / α-グルコシダーゼ / 茎 / ニゾゥコギ / 刺五加 / 化学成分 / 絶滅危惧種 / 薬用植物 … More Except Principal Investigator 漢方薬 / 駆お血剤 / 抗酸化 / BPSD / 認知症 / aldose reductase / AGEs / プロティンチロシンホスファターゼ1B / 抗酸化活性 / 糖尿病 / 通導散 / 治打撲一方 / 大柴胡湯 / 抗酸化作用 / 麻子仁丸 / 糖代謝異常疾患 / 医療用漢方製剤 / lignan / Trichosanthes　kirilowii / tetrahydrofuran lignan / がん幹細胞抑制活性 / Cancer stem cells / Mammosphere formation / Trichosanthes kirilowii / Euphorbia fischeriana / Saururus chinensis / 薬学 / サポニン / ヤブコウジ / 創薬 / 天然物 / 抗がん剤 Less

MSフラグメンテーションに基づいたプログラミングによる生薬成分解析の高速化Principal Investigator
- Principal Investigator
  
  李巍
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Toho University
Structure-Activity Relationship Study of Macrocyclic Daphnane Diterpenoids Towards Drug discovery for HIV CurePrincipal Investigator
- Principal Investigator
  
  Li Wei
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Toho University
Study on effectiveness of Kampo medicines for "negative" surrounding symptoms of dementia
- Principal Investigator
  
  KOIKE Kazuo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Toho University
Study on bioactive diterpenoids from medicinal plants of Thymelaeaceae and Euphorbiaceae familiesPrincipal Investigator
- Principal Investigator
  
  LI Wei
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Toho University
Evaluation of Kampo Prescriptions as Therapeutic Agents for Glucose Metabolism Disorders
- Principal Investigator
  
  KOIKE Kazuo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Toho University
Phytochemical investigation of Daphnane-type diterpenoids aiming to discover next generation anti-HIV drugsPrincipal Investigator
- Principal Investigator
  
  LI Wei
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Toho University
Investigation of new anti-cancer agents with selective anti-proliferative activities
- Principal Investigator
  
  ASADA Yoshihisa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Tokyo University of Science
Investigation of triterpenoid saponins from Ardisia plants with selective anti-proliferative activities against liver cancer cells
- Principal Investigator
  
  KOIKE Kazuo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toho University
Discovery of novel natural PTP1B inhibitors as antidiabetes drug seedsPrincipal Investigator
- Principal Investigator
  
  LI Wei
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Toho University
Chemical study on endangered medicinal plants in northeastern Region of ChinaPrincipal Investigator
- Principal Investigator
  
  LI Wei
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Toho University

[Journal Article] LC-MS identification, isolation, and structural elucidation of anti-HIV macrocyclic daphnane orthoesters from Edgeworthia chrysantha2024
- Author(s)
  Otsuki Kouharu、Kobayashi Tsubasa、Nakamura Kazuki、Kikuchi Takashi、Huang Li、Chen Chin-Ho、Koike Kazuo、Li Wei
- Journal Title
  
  Fitoterapia
  
  Volume: 172 Pages: 105731-105731
- DOI
  10.1016/j.fitote.2023.105731
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Journal Article] Molecular networking as a natural products discovery strategy2023
- Author(s)
  Zhang Mi、Otsuki Kouharu、Li Wei
- Journal Title
  
  Acta Materia Medica
  
  Volume: 2 Issue: 2 Pages: 126-141
- DOI
  10.15212/amm-2023-0007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06619
[Journal Article] Identification of Daphnane Diterpenoids from Wikstroemia indica Using Liquid Chromatography with Tandem Mass Spectrometry2023
- Author(s)
  Zhang Mi、Otsuki Kouharu、Takahashi Reo、Kikuchi Takashi、Zhou Di、Li Ning、Li Wei
- Journal Title
  
  Plants
  
  Volume: 12 Issue: 20 Pages: 3620-3620
- DOI
  10.3390/plants12203620
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Journal Article] Tigliane and daphnane diterpenoids from Thymelaeaceae family: chemistry, biological activity, and potential in drug discovery2023
- Author(s)
  Otsuki Kouharu、Li Wei
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 77 Issue: 4 Pages: 625-643
- DOI
  10.1007/s11418-023-01713-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06619
[Journal Article] Daphnepedunins G and H, anti-HIV macrocyclic 3,4-seco-daphnane orthoesters from Daphne pedunculata2023
- Author(s)
  Tan Lingjian、Otsuki Kouharu、Zhang Mi、Kikuchi Takashi、Zhou Di、Li Ning、Huang Li、Chen Chin-Ho、Li Wei
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 78 Issue: 1 Pages: 114-122
- DOI
  10.1007/s11418-023-01750-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Journal Article] Daphnepedunins A-F, Anti-HIV Macrocyclic Daphnane Orthoester Diterpenoids from Daphne pedunculata2022
- Author(s)
  Tan Lingjian、Otsuki Kouharu、Zhang Mi、Kikuchi Takashi、Okayasu Misaki、Azumaya Isao、Zhou Di、Li Ning、Huang Li、Chen Chin-Ho、Li Wei
- Journal Title
  
  Journal of Natural Products
  
  Volume: 85 Issue: 12 Pages: 2856-2864
- DOI
  10.1021/acs.jnatprod.2c00894
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Journal Article] A feruloylated acylglycerol isolated from Wikstroemia pilosa and its distribution in ten plants of Wikstroemia species2022
- Author(s)
  Zhang Mi、Otsuki Kouharu、Kato Shizuka、Ikuma Yuito、Kikuchi Takashi、Li Ning、Koike Kazuo、Li Wei
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: - Issue: 3 Pages: 680-685
- DOI
  10.1007/s11418-022-01621-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Journal Article] Anti-HIV Tigliane-Type Diterpenoids from the Aerial Parts of Wikstroemia lichiangensis2022
- Author(s)
  Zhou Di、Otsuki Kouharu、Zhang Mi、Chen Gang、Bai Zi-Song、Yu Haotian、Kikuchi Takashi、Huang Li、Chen Chin-Ho、Li Wei、Li Ning
- Journal Title
  
  Journal of Natural Products
  
  Volume: 85 Issue: 6 Pages: 1658-1664
- DOI
  10.1021/acs.jnatprod.1c01195
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Journal Article] Anti-HIV Macrocyclic Daphnane Orthoesters with an Unusual Macrocyclic Ring from Edgeworthia chrysantha2022
- Author(s)
  Asada Yoshihisa、Otsuki Kouharu、Morooka Miki、Huang Li、Chen Chin-Ho、Koike Kazuo、Li Wei
- Journal Title
  
  Journal of Natural Products
  
  Volume: 85 Issue: 10 Pages: 2399-2405
- DOI
  10.1021/acs.jnatprod.2c00618
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Journal Article] LC-MS Identification, Isolation, and Structural Elucidation of Anti-HIV Tigliane Diterpenoids from Wikstroemia lamatsoensis2021
- Author(s)
  Zhang Mi、Otsuki Kouharu、Kikuchi Takashi、Bai Zi-Song、Zhou Di、Huang Li、Chen Chin-Ho、Morris-Natschke Susan L.、Lee Kuo-Hsiung、Li Ning、Koike Kazuo、Li Wei
- Journal Title
  
  Journal of Natural Products
  
  Volume: 84 Issue: 8 Pages: 2366-2373
- DOI
  10.1021/acs.jnatprod.1c00570
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Journal Article] Natural products against HIV latency2021
- Author(s)
  Otsuki Kouharu、Zhang Mi、Li Wei
- Journal Title
  
  Acupuncture and Herbal Medicine
  
  Volume: 1 Issue: 1 Pages: 10-21
- DOI
  10.1097/hm9.0000000000000004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06619
[Journal Article] Identification of anti-HIV macrocyclic daphnane orthoesters from Wikstroemia ligustrina by LC-MS analysis and phytochemical investigation2021
- Author(s)
  Otsuki Kouharu、Zhang Mi、Kikuchi Takashi、Tsuji Minami、Tejima Miyuko、Bai Zi-Song、Zhou Di、Huang Li、Chen Chin-Ho、Lee Kuo-Hsiung、Li Ning、Koike Kazuo、Li Wei
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 75 Issue: 4 Pages: 1058-1066
- DOI
  10.1007/s11418-021-01551-9
- NAID
  40022683560
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Journal Article] Effects of Oral Administration of Low Dose Estrogen-Progestin on Mice and Combined Effect of Kampo Medicine2020
- Author(s)
  Asako Okamura, Kouharu Otsuki, Haruka Wada, Reiko Yokosawa, Eriko Nakadai, Kana Sekiguchi, Wei Li, Kazuo Koike
- Journal Title
  
  応用薬理
  
  Volume: 99 Pages: 89-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06724
[Journal Article] Daphneodorins A-C, Anti-HIV Gnidimacrin Related Macrocyclic Daphnane Orthoesters from Daphne odora2019
- Author(s)
  Otsuki Kouharu、Li Wei、Asada Yoshihisa、Chen Chin-Ho、Lee Kuo-Hsiung、Koike Kazuo
- Journal Title
  
  Organic Letters
  
  Volume: 22 Issue: 1 Pages: 11-15
- DOI
  10.1021/acs.orglett.9b03539
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08348
[Journal Article] Synthesis and Structure?Activity Relationship Correlations of Gnidimacrin Derivatives as Potent HIV-1 Inhibitors and HIV Latency Reversing Agents2019
- Author(s)
  Liu Qingbo、Cheng Yung-Yi、Li Wei、Huang Li、Asada Yoshihisa、Hsieh Min-Tsang、Morris-Natschke Susan L.、Chen Chin-Ho、Koike Kazuo、Lee Kuo-Hsiung
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 62 Issue: 15 Pages: 6958-6971
- DOI
  10.1021/acs.jmedchem.9b00339
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08348
[Journal Article] Identification, structural modification, and dichotomous effects on human immunodeficiency virus type 1 (HIV-1) replication of ingenane esters from Euphorbia kansui2018
- Author(s)
  Liu Qingbo、Li Wei、Huang Li、Asada Yoshihisa、Morris-Natschke Susan L.、Chen Chin-Ho、Lee Kuo-Hsiung、Koike Kazuo
- Journal Title
  
  European Journal of Medicinal Chemistry
  
  Volume: 156 Pages: 618-627
- DOI
  10.1016/j.ejmech.2018.07.020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08348
[Journal Article] ent-Atisane diterpenoids from Euphorbia fischeriana inhibit mammosphere formation in MCF-7 cells2016
- Author(s)
  Xinzhu Kuang, Wei Li, Yuichiro Kanno, Naoya Yamashita, Kiyomitsu Nemoto, Yoshihisa Asada, Kazuo Koike
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 70 Issue: 1 Pages: 120-126
- DOI
  10.1007/s11418-015-0940-6
- NAID
  40020680985
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460136
[Journal Article] Identification and evaluation of magnolol and chrysophanol as the principle protein tyrosine phosphatase-1B inhibitory compounds in a Kampo medicine, Masiningan2016
- Author(s)
  Toshihisa Onoda, Wei Li, Tatsunori Sasaki, Megumi Miyake, Koji Higai, Kazuo Koike
- Journal Title
  
  Journal of Ethnopharmacology
  
  Volume: 186 Pages: 84-90
- DOI
  10.1016/j.jep.2016.03.063
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08003
[Journal Article] Gnidimacrin, a Potent Anti-HIV Diterpene, Can Eliminate Latent HIV-1 Ex Vivo by Activation of Protein Kinase C β2015
- Author(s)
  Weihong Lai, Li Huang, Lei Zhu, Guido Ferrari, Cliburn Chan, Wei Li, Kuo-Hsiung Lee, and Chin-Ho Chen
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 58 Issue: 21 Pages: 8638-8646
- DOI
  10.1021/acs.jmedchem.5b01233
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460133
[Journal Article] Protein tyrosine phosphatase 1B inhibitory activities of ursane- and lupane-type triterpenes from Sorbus pohuashanensis2014
- Author(s)
  Dongxia Li, Wei Li, Koji Higai, Kazuo Koike
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 68(2) Issue: 2 Pages: 427-431
- DOI
  10.1007/s11418-013-0804-x
- NAID
  40020023351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790025
[Journal Article] Protein tyrosine phosphatase 1B inhibitory activity of lavandulyl flavonoids from roots of Sophora flavescens2014
- Author(s)
  Tatsunori Sasaki, Wei Li, Koji Higai, Tran Hong Quang, Young Ho Kim, Kazuo Koike
- Journal Title
  
  Planta Medica
  
  Volume: 80 Issue: 07 Pages: 557-560
- DOI
  10.1055/s-0034-1368400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790025
[Journal Article] Evaluation of 147 Kampo Prescriptions as novel protein tyrosine phosphatase 1B (PTP1B) inhibitory agents2014
- Author(s)
  Toshihisa Onoda, Wei Li, Koji Higai, Kazuo Koike
- Journal Title
  
  BMC Complementary and Alternative Medicine
  
  Volume: 14 Issue: 1 Pages: 64-64
- DOI
  10.1186/1472-6882-14-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790025
[Journal Article] Cyclamin, a natural 13,28-epoxy triterpenoid saponin, synergistically enhances cytotoxicity of chemotherapeutic drugs in human liver cancer cells but not non-neoplastic liver cells2014
- Author(s)
  Qin Li, Lin Deng, Wei Li, Kazuo Koike
- Journal Title
  
  Planta Medica
  
  Volume: ８０ Issue: 05 Pages: 409-414
- DOI
  10.1055/s-0034-1368198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590027
[Journal Article] Evaluation of licorice flavonoids as protein tyrosine phosphatase 1B inhibitors2013
- Author(s)
  Wei Li, Songpei Li, Koji Higai, Tatsunori Sasaki, Yoshihisa Asada, Shigeru Ohshima, Kazuo Koike
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 23 Issue: 21 Pages: 5836-5839
- DOI
  10.1016/j.bmcl.2013.08.102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790025
[Journal Article] A dihydrochalcone and several homoisoflavonoids from Polygonatum odoratum are activators of adenosine monophosphate-activated protein kinase2013
- Author(s)
  Huanjie Guo, Huanxin Zhao, Yuichiro Kanno, Wei Li, Yanling Mu, Xinzhu Kuang, Yoshio Inouye, Kazuo Koike, Haipeng Jiang, Hong Bai
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 23 Issue: 11 Pages: 3137-3139
- DOI
  10.1016/j.bmcl.2013.04.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790025, KAKENHI-PROJECT-23790104, KAKENHI-PROJECT-25460175
[Journal Article] 13,28-Epoxy triterpenoid saponins from Ardisia japonica selectively inhibit proliferation of liver cancer cells without affecting normal liver cells2012
- Author(s)
  Qin Li, Wei Li, Lin-Ping Hui, Chen-Yang Zhao, Lin He, Kazuo Koike
- Journal Title
  
  Bioorganic & medicinal chemistry letters
  
  Volume: 22 Issue: 19 Pages: 6120-6125
- DOI
  10.1016/j.bmcl.2012.08.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590027
[Journal Article] Chemical Constituents from Sambucus adnata and Their Protein-Tyrosine Phosphatase 1B Inhibitory Activities2011
- Author(s)
  Tatsunori Sasaki, Wei Li, Haruna Morimura, Songpei Li, Qin Li, Yoshihisa Asada, Kazuo Koike
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 59 Issue: 11 Pages: 1396-1399
- DOI
  10.1248/cpb.59.1396
- NAID
  130001274816
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790025
[Journal Article] Biologically active triterpenoia saponins from Acanthopanax senticosus2007
- Author(s)
  Wenhong Jiang, Wei Li, Likun Han, Lijuan Liu, Qingbo Zhang, Shujie Zhang, Tamotsu Nikaido, Kazuo Koike
- Journal Title
  
  Journal of Natural Products 69
  
  Pages: 1577-1581
- Data Source
  KAKENHI-PROJECT-18790102
[Journal Article] Pancreatic lipase-inhibiting triterpenoid saponins from fruits of Acanth opanax senticosus2007
- Author(s)
  Fang Li, Wei Li, Hongwei Fu, Qingbo Zhang, Kazuo Koike
- Journal Title
  
  Chemical & Pharmaceutical Bulletin 55
  
  Pages: 1087-1089
- NAID
  110006317181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790102
[Journal Article] Pancreatic lipase-inhibiting triterpenoid saponins from fruits of Acanthopanax senticosus2007
- Author(s)
  Fang Li, Wei Li, Hongwei Fu, Qingbo Zhang, Kazuo Koike
- Journal Title
  
  Chemical & Pharmaceutical Bulletin 55
  
  Pages: 1087-1089
- NAID
  110006317181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790102
[Journal Article] Biologically active triterpenoid saponins from Acanthopanax senticosus2006
- Author(s)
  Wenhong Jiang, Wei Li, Likun Han, Lijuan Liu, Qingbo Zhang, Shujie Zhang, Tamotsu Nikaido, Kazuo Koike
- Journal Title
  
  Journal of Natural Products 69
  
  Pages: 1577-1581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790102
[Presentation] ジンチョウゲ科植物オニシバリ果実のダフナン型ジテルペノイドに関する成分研究2024
- Author(s)
  木村真悠、高宮璃子、大月興春、菊地崇、李巍
- Organizer
  日本薬学会第144回年会
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] Anti-HIV macrocyclic daphnane orthoesters from Edgeworthia chrysantha2023
- Author(s)
  Kouharu Otsuki、Mi Zhang、LingJian Tan、Li Huang、Chin-Ho Chen、Takashi Kikuchi、Kazuo Koike、Wei Li
- Organizer
  The 31st International Symposium on the Chemistry of Natural Products and the 11th International Congress on Biodiversity (ISCNP31 & ICOB11)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] LC-MSによるジンチョウゲ科アオガンピ属植物Wikstroemia stenophyllaに含まれるジテルペノイドの解析2023
- Author(s)
  張米、大月興春、菊地崇、李寧、李巍
- Organizer
  日本生薬学会第69回年会
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] LC-ESI-MS/MSによるダフナン型ジテルペノイドの構造解析2023
- Author(s)
  張米、大月興春、譚霊剣、菊地崇、李巍
- Organizer
  日本薬学会第143回年会
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] Anti-HIV daphnane diterpenoids from Daphne pedunculata2023
- Author(s)
  Lingjian Tan、Kouharu Otsuki、Mi Zhang、Takashi Kikuchi、Ning Li、Chin-Ho Chen、Wei Li
- Organizer
  The 12th Joint Seminar on Biomedical Sciences (12th JSOBMS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] Anti-HIV tigliane diterpenoids from Wikstroemia scytophylla and W. lamatsoensis2023
- Author(s)
  Mi Zhang、Kouharu Otsuki、Takashi Kikuchi、Chin-Ho Chen、Ning Li、Wei Li
- Organizer
  The 12th Joint Seminar on Biomedical Sciences (12th JSOBMS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] LC-MSを用いたジンチョウゲ科植物Daphne pedunculataに含まれるダフナン型ジテルペノイドの成分解析2023
- Author(s)
  譚霊剣、大月興春、張米、菊地崇、李寧、李巍
- Organizer
  日本生薬学会第69回年会
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] Discovery of anti-HIV Daphnane Diterpenoids from plants of Thymelaeaceae Family2023
- Author(s)
  Wei Li
- Organizer
  The 12th CPA-KSP-JSP Joint Symposium on Pharmacognosy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] ジンチョウゲ科植物Daphne pedunculataのダフナン型ジテルペノイドに関する成分研究2023
- Author(s)
  譚霊剣、大月興春、張米、菊地崇、Chen Chin-Ho、李寧、李巍
- Organizer
  日本薬学会第143回年会
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] ジンチョウゲ科植物オニシバリ果実のダフナン型ジテルペノイドに関する成分研究2023
- Author(s)
  大月興春、細矢千尋、菊地崇、李巍
- Organizer
  日本生薬学会第69回年会
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] LC-MS分析によるジンチョウゲ科植物Daphne tanguticaに含まれるダフナン型ジテルペノイドの成分解析(2)2023
- Author(s)
  小牧正佳、大月興春、菊地崇、李巍
- Organizer
  日本薬学会第143回年会
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] LC-MS分析によるジンチョウゲ科植物オニシバリの果実に含まれるダフナン型ジテルペノイドの成分解析2023
- Author(s)
  大月興春、加藤碧、菊地崇、李巍
- Organizer
  日本薬学会第143回年会
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] LC-MSを活用したジンチョウゲ科薬用植物Wikstroemia indicaに含まれるジテルペノイドの成分研究2022
- Author(s)
  張米、大月興春、菊地崇、李寧、李巍
- Organizer
  日本生薬学会第68回年会
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] ジンチョウゲ科植物ミツマタEdgeworthia chrysanthaのジテルペノイドに関する成分研究2022
- Author(s)
  大月興春、中村一希、小林翼、菊地崇、小池一男、李巍
- Organizer
  日本生薬学会第68回年会
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] ジンチョウゲ科植物Daphne pedunculataの抗HIV活性大環状ダフナン型ジテルペノイドに関する成分研究2022
- Author(s)
  譚霊剣、大月興春、張米、菊地崇、Chin-Ho Chen、李寧、李巍
- Organizer
  日本薬学会第142年会（名古屋）
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] LC-MS を活用したジンチョウゲ科植物由来の抗HIV 活性チグリアン型ジテルペノイドの探索研究2022
- Author(s)
  張米、大月興春、菊地崇、Chen Chin-Ho、李寧、李巍
- Organizer
  第34回バイオメディカル分析科学シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] LC-MS分析によるジンチョウゲ科植物由来のダフナン型ジテルペノイドの迅速同定2022
- Author(s)
  大月興春、張米、菊地崇、李巍
- Organizer
  第34回バイオメディカル分析科学シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] LC-MS/MSによるジンチョウゲ科薬用植物Daphne tanguticaに含まれるジテルペノイドの成分分析2022
- Author(s)
  島田茜、大月興春、譚霊剣、張米、菊地崇、李寧、李巍
- Organizer
  日本薬学会第142年会（名古屋）
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] LC-MSを活用したWikstroemia ligustrinaの抗HIV活性大環状ダフナン型ジテルペノイドに関する成分研究2021
- Author(s)
  大月興春、張米、菊地崇、Chin-Ho Chen、 Kuo-Hsiung Lee、李寧、小池一男、李巍
- Organizer
  日本生薬学会第67回年会（東京）
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] Discovery of novel anti-HIV agents from traditional medicinal plants2021
- Author(s)
  Wei Li
- Organizer
  The 13th International Conference and Exhibition on Nutraceuticals and Functional Foods
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] Gnidimacrin And Its Derivatives Against HIV-1 Latency2021
- Author(s)
  Wei Li
- Organizer
  The 3rd Lijiang International Forum on Pharmaceutical Sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] ジンチョウゲ科植物Daphne pedunculata由来の新規大環状ダフナン型ジテルペノイドの構造解析2021
- Author(s)
  譚霊剣、大月興春、張米、菊地崇、李寧、李巍
- Organizer
  日本生薬学会第67回年会（東京）
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] ジンチョウゲ科アオガンピ属植物由来の抗HIV活性チグリアン型ジテルペノイドの探索研究2021
- Author(s)
  張米、大月興春、菊地崇、Chen Chin-Ho、Lee Kuo-Hsiung、李寧、李巍
- Organizer
  第23回天然薬物の応用と開発シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06619
[Presentation] Gnidimacrin and its derivatives against HIV-1 latency2020
- Author(s)
  Wei Li
- Organizer
  22nd International Conference on Emerging Infectious Diseases in the Pacific Rim
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08348
[Presentation] ジンチョウゲ科植物Wikstroemia scytophyllaの化学成分研究2020
- Author(s)
  山本　明日香、大月　興春、李　寧、李　巍、小池　一男
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08348
[Presentation] Discovery of anti-HIV diterpenoids from medicinal plants of Thymelaeaceae and Euphorbiaceae families2019
- Author(s)
  Wei Li
- Organizer
  11th Joint Seminar on Biomedical Sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08348
[Presentation] Tigliane diterpenoids from Wikstroemia scytophylla2019
- Author(s)
  Mi Zhang、Asuka Yamamoto、Kouharu Otsuki、Wei Li、Kazuo Koike
- Organizer
  11th Joint Seminar on Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08348
[Presentation] ジンチョウゲ科薬用植物ミツマタのダフナン型ジテルペンに関する成分研究2019
- Author(s)
  師岡美喜、大月興春、李巍、浅田善久、小池一男
- Organizer
  日本薬学会第139年会（千葉）
- Data Source
  KAKENHI-PROJECT-17K08348
[Presentation] 通導散及びその構成生薬の抗酸化活性の検討2019
- Author(s)
  竹元裕明、東福真理菜、堀内まなみ、籏理英、佐藤直子、李巍、小池一男
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K06724
[Presentation] Lessons from Nature: Innovation of Traditional Medicines2019
- Author(s)
  李巍
- Organizer
  日中医薬健康領域ハイレベル研究フォーラム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06724
[Presentation] 沈丁花由来の抗HIV活性を有する大環状daphnane型ジテルペノイドに関する研究2019
- Author(s)
  大月　興春、李　巍、浅田　善久、Chen Chin-Ho、Lee Kuo-Hsiung、小池　一男
- Organizer
  第56回植物化学シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08348
[Presentation] ジンチョウゲ科薬用植物ジンチョウゲのダフナン型ジテルペンに関する成分研究2019
- Author(s)
  大月興春、三浦香純、李巍、浅田善久、小池一男
- Organizer
  日本薬学会第139年会（千葉）
- Data Source
  KAKENHI-PROJECT-17K08348
[Presentation] 生薬甘遂由来の抗HIV活性成分の探索研究2018
- Author(s)
  李　巍、劉　慶博、Chen Chin-Ho、Lee Kuo-Hsiung、小池　一男
- Organizer
  日本薬学会第１３８年会（金沢）
- Data Source
  KAKENHI-PROJECT-17K08348
[Presentation] ジンチョウゲ科およびトウダイクサ科薬用植物から抗HIVジテルペノイドの探索研究2018
- Author(s)
  李巍、劉慶博、浅田善久、小池一男
- Organizer
  第22回天然薬物の応用と開発シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08348
[Presentation] ジンチョウゲ科薬用植物ジンチョウゲの成分研究2018
- Author(s)
  大月興春、三浦香純、李巍、竹元裕明、浅田善久、小池一男
- Organizer
  日本生薬学会第65回年会（広島）
- Data Source
  KAKENHI-PROJECT-17K08348
[Presentation] Discovery of anti-HIV diterpenoids from medicinal plants of Thymelaeaceae and Euphorbiaceae2018
- Author(s)
  Wei Li
- Organizer
  The Fifth World Education Congress of Chinese Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08348
[Presentation] 抗HIV天然物gnidimacrinの化学誘導体合成と構造活性相関2018
- Author(s)
  劉　慶博、李　巍、Chen Chin-Ho、Lee Kuo-Hsiung、小池　一男
- Organizer
  日本薬学会第１３８年会（金沢）
- Data Source
  KAKENHI-PROJECT-17K08348
[Presentation] 医療用漢方製剤のin vivo抗酸化作用2018
- Author(s)
  竹元裕明、中村愛、徳倉絵美、佐藤直子、李巍、小池一男
- Organizer
  日本生薬学会第65年会
- Data Source
  KAKENHI-PROJECT-18K06724
[Presentation] トウダイグサ科およびジンチョウゲ科薬用植物由来の潜伏HIVを活性化する抗HIV活性天然物の探索研究2018
- Author(s)
  李巍、劉慶博、浅田善久、Chen Chin-Ho、Lee Kuo-Hsiung、小池一男
- Organizer
  第20回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08348
[Presentation] 四塩化炭素誘発急性肝障害モデルマウスにおける大柴胡湯及び治打撲一方の抗酸化作用の評価2017
- Author(s)
  小松加奈、栗山典子、李巍、小池一男
- Organizer
  日本生薬学会第64回年会（千葉）
- Data Source
  KAKENHI-PROJECT-15K08003
[Presentation] 医療用漢方製剤147処方の抗酸化活性に関する研究2016
- Author(s)
  竹内未央、佐藤直子、小野田稔久、桧貝孝慈、李巍、小池一男
- Organizer
  日本生薬学会第63回年会
- Place of Presentation
  富山国際会議場（富山県・富山市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K08003
[Presentation] 新しいプロテインチロシンフォスファターゼ1B(PTP1B)阻害薬としての147医療用漢方製剤の評価2014
- Author(s)
  小野田稔久,李巍,真坂亙,小池一男
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-30
- Data Source
  KAKENHI-PROJECT-23790025
[Presentation] ニガキ科アルカロイドのプロテインチロシンホスファターゼ1B阻害活性2014
- Author(s)
  佐々木辰憲,李巍,桧貝孝慈,小池一男
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-28
- Data Source
  KAKENHI-PROJECT-23790025
[Presentation] がん幹細胞抑制作用を示すSaururus chinensisの活性成分の同定及び作用機序の解明2014
- Author(s)
  山下直哉, 菅野裕一朗, 佐藤ちひろ, 若井将志, 遠藤慎平, 李巍, 小池一男, 浅田善久, 井上義雄
- Organizer
  第134回日本薬学会年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25460136
[Presentation] Discovery of novel natural compounds from taditional medicines as new drug seeds2014
- Author(s)
  李巍
- Organizer
  寧夏薬学会2014年度学術年会
- Place of Presentation
  銀川市（中国）
- Year and Date
  2014-12-13
- Invited
- Data Source
  KAKENHI-PROJECT-26460133
[Presentation] 苦参由来フラボノイドのPTP1B阻害活性について2013
- Author(s)
  佐々木辰憲,李巍,桧貝孝慈,小池一男, Tran Hong Quang, Young Ho Kim
- Organizer
  日本生薬学会第60回年会
- Place of Presentation
  北海道
- Year and Date
  2013-09-08
- Data Source
  KAKENHI-PROJECT-23790025
[Presentation] 覆盆子のPTP1B阻害活性成分に関する研究2012
- Author(s)
  李松沛,李巍,小池一男
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23790025
[Presentation] Study on Natural Products for Treatment of Lifestyle Related Diseases2011
- Author(s)
  Wei Li
- Organizer
  International Conference of Translation Herbal Medicine 2011
- Place of Presentation
  Hualien, Taiwan
- Year and Date
  2011-05-17
- Data Source
  KAKENHI-PROJECT-23790025
[Presentation] 中国原産薬用植物のPTP1B阻害活性について2011
- Author(s)
  田井雅子,李松沛,寺尾美沙也,李巍,小池一男,王英華
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  船橋
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-23790025
[Presentation] Licorice flavonoids as protein-tyrosine phosphatase 1B inhibitors with cellular activity2011
- Author(s)
  Wei Li, Songpei Li, Koji Higai, Kazuo Koike
- Organizer
  The 6th CCTNM-KSP-JSP Joint Symposium on Pharmacognosy
- Place of Presentation
  Shenyang, china
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-23790025
[Presentation] Licorice flavonoids as protein-tyrosine phosphatase 1B inhibitors2011
- Author(s)
  LI Wei, LI Songpei, HIGAI Koji, KOIKE Kazuo
- Organizer
  The 6th CCTNM-KSP-JSP Joint Symposium on Pharmacognosy
- Place of Presentation
  Shenyang, China
- Data Source
  KAKENHI-PROJECT-23790025
[Presentation] Sambucus adnataの化学成分研究及びPTP1B阻害活性について2011
- Author(s)
  森村春菜,佐々木辰慶,李巍,李松沛,小池一男
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  船橋
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-23790025
[Presentation] 13,28-Epoxy triterpenoid saponins from Ardisia japonica and their selective antiproliferative activity on human liver cancer cells
- Author(s)
  Wei Li, Qin Li, Kazuo Koike
- Organizer
  The 7th KSP-JSP-CCTCNM Joint Symposium on Pharmacognosy
- Place of Presentation
  韓国ソウル
- Data Source
  KAKENHI-PROJECT-24590027
[Presentation] Saururus chinensis の成分研究
- Author(s)
  若井将志, 遠藤慎平, 李巍, 小池一男, 管野裕一朗, 井上義雄, 浅田善久
- Organizer
  第57回日本薬学会関東支部大会
- Place of Presentation
  帝京大学　板橋キャンパス
- Data Source
  KAKENHI-PROJECT-25460136
[Presentation] ヒト肝がん細胞におけるアルジシアサポニンと化学療法剤の併用効果
- Author(s)
  李巍, Li Qin,小池一男
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学黒髪キャンパス（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24590027
[Presentation] ニガキ科アルカロイドのプロテインチロシンホスファターゼ1B阻害活性
- Author(s)
  佐々木辰憲, 李巍, 桧貝孝慈, 小池一男
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学黒髪キャンパス（熊本）
- Data Source
  KAKENHI-PROJECT-23790025
[Presentation] LC-MS分析を活用したマンリョウArdisia crenata根の新規微量トリテルペノイドサポニンの探索研究
- Author(s)
  劉洋華, 李巍, 匡薪竹,馬玲,小池一男
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24590027
[Presentation] 苦参由来フラボノイドのPTP1B 阻害活性について
- Author(s)
  佐々木辰憲 , 李巍 , 桧貝孝慈 , 小池一男 , Tran Hong, Quang, Young Ho, Kim
- Organizer
  日本生薬学会第60回年会
- Place of Presentation
  北海道医療大学・当別キャンパス（北海道）
- Data Source
  KAKENHI-PROJECT-23790025
[Presentation] ヤブコウジ属薬用植物のトリテルペノイドサポニン成分解析および選択的肝がん細胞毒性
- Author(s)
  李巍, Li Qin, 馬玲, 小池一男
- Organizer
  第１９回天然薬物の開発と応用シンポジウム
- Place of Presentation
  大阪大学会館(大阪府)
- Data Source
  KAKENHI-PROJECT-24590027
[Presentation] 新しいプロテインチロシンフォスファターゼ1B(PTP1B)阻害薬としての147医療用漢方製剤の評価
- Author(s)
  小野田稔久, 李巍, 真坂亙, 小池一男
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学黒髪キャンパス（熊本）
- Data Source
  KAKENHI-PROJECT-23790025
[Presentation] ヤブコウジ由来の13,28-エポキシトリテルペノイドサポニンの肝がん細胞毒性について
- Author(s)
  李巍, 小池一男, Li Qin
- Organizer
  日本生薬学会第59回年会
- Place of Presentation
  かずさアカデミアパーク(千葉県)
- Data Source
  KAKENHI-PROJECT-24590027

1. KOIKE Kazuo (30130363)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. ASADA Yoshihisa (90118779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. KANNO Yuichiro (40453849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 大月興春 (50936961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. LEE Kuo-Hsiung

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. CHEN Chin-Ho

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

LI Wei 李 巍

Research Projects

Research Products

Co-Researchers

MSフラグメンテーションに基づいたプログラミングによる生薬成分解析の高速化Principal Investigator

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Structure-Activity Relationship Study of Macrocyclic Daphnane Diterpenoids Towards Drug discovery for HIV CurePrincipal Investigator

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Review Section

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Study on effectiveness of Kampo medicines for "negative" surrounding symptoms of dementia

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Study on bioactive diterpenoids from medicinal plants of Thymelaeaceae and Euphorbiaceae familiesPrincipal Investigator

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Evaluation of Kampo Prescriptions as Therapeutic Agents for Glucose Metabolism Disorders

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Phytochemical investigation of Daphnane-type diterpenoids aiming to discover next generation anti-HIV drugsPrincipal Investigator

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Investigation of new anti-cancer agents with selective anti-proliferative activities

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Investigation of triterpenoid saponins from Ardisia plants with selective anti-proliferative activities against liver cancer cells

Principal Investigator

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Discovery of novel natural PTP1B inhibitors as antidiabetes drug seedsPrincipal Investigator

Principal Investigator

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Chemical study on endangered medicinal plants in northeastern Region of ChinaPrincipal Investigator

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[Journal Article] LC-MS identification, isolation, and structural elucidation of anti-HIV macrocyclic daphnane orthoesters from Edgeworthia chrysantha2024

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[Journal Article] Molecular networking as a natural products discovery strategy2023

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[Journal Article] Identification of Daphnane Diterpenoids from Wikstroemia indica Using Liquid Chromatography with Tandem Mass Spectrometry2023

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DOI

Data Source

[Journal Article] Tigliane and daphnane diterpenoids from Thymelaeaceae family: chemistry, biological activity, and potential in drug discovery2023

LI Wei 李巍