KITAMURA Masanori 北村正敬

Researcher Number	90333062
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2011 – 2013: 山梨大学, 医学工学総合研究部, 教授 2007 – 2012: University of Yamanashi, Interdisciplinary Gmduaie School of Medicine and Engineering, Professor 2011: 山梨大学, 医学部, 教授 2006: 山梨大学, 大学院医学工学総合研究部, 教授 2003 – 2005: 山梨大学, 大学院・医学工学総合研究部, 教授 2002: 東京慈恵会医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Kidney internal medicine / Risk sciences of radiation/Chemicals / Kidney internal medicine Except Principal Investigator Kidney internal medicine / Ophthalmology / Urology
Keywords	Principal Investigator シグナル伝達 / バイオセンサー / トランスジェニックマウス / 糸球体腎炎 / NF-kB / メサンギウム細胞 / NF-κB / 炎症 / 小胞体ストレス / 芳香族炭化水素受容体 … More / 喫煙 / タバコ煙 / 分泌型アルカリフォスファターゼ / ダイオキシン / 遺伝子導入 / signal transduction / endotoxemia / heavy metal toxicity / transeenic mouse / secreted alkaline nhosohatase / endonlasmic reticulum stres / inflammation / biosensor / 分泌方アルカリフォスファターゼ / 細胞移植 / 分泌型アルカリフォスファター / 遺伝子治療 / 病理 / シゲナル伝達 / 重金属 / 急性腎不全 / 敗血症 / 重金属中毒 / DSS腸炎 / 漬瘍性大腸炎 / 治療 / 免疫担当細胞 / 遺伝子改変マウス / 潰瘍性大腸炎 / サイトカイン / 糸球体上皮細胞 / 尿細管細胞 / 腎臓病学 / 胞体ストレス / 尿細管傷害 / 3'-deoxyadenosine / mTOR / Akt / 細胞死(アポトーシス) / 腎尿細管障害 / ATF6 / IRE1 / 4-phenylbutyric acid / 3’-deoxyadenosine / 細胞死（アポトーシス） / アポトーシス / 腎疾患 / 病理学 / 多環芳香族炭化水素 / 環境科学 / 大気汚染 / リポーターアッセイ / ダイオキシン応答配列 / 血管再生 / 分子生物学 / 幹細胞 / 再生医学 / 糸球体硬化 / 腎不全 … More Except Principal Investigator ギャップ結合 / 酸化ストレス / 腎臓 / connexin43 / シグナル伝達 / 細胞死 / コネキシン / 内皮細胞 / Calcium / Protein kinase A / Phosphodiesterase 3 / Nitric oxide / Endothelial cells / Connexin43 / Gap junction / Mesangial cells / 糸球体 / protein kinaseA / 内比細胞 / protein kinase A / PDGF / nitric oxide / gap結合 / メサンギウム細胞 / 炎症 / ヘミチャネル / コネキシン43 / ATP / AMPK / 虚血 / 病理学 / 眼表面 / 角膜 / 涙腺 / ドライアイ / 喫煙 / 眼細胞生物学 / 腎臟 / 傍糸球体装置 / cAMP / 細胞間コミュニケーション / レニン分泌細胞 / コネクシン / レニン / 生理学 / 細胞毒性 / 尿細管上皮細胞 / 抗生物質 / 薬理学 / 尿細管細胞 / aminoglycosides / 小胞体ストレス / コネクシン43 / 血管由来過分極因子 / レニン産生細胞 Less

小胞体ストレス応答系が有する多彩な抗炎症的役割の網羅的解明と新規治療戦略の樹立Principal Investigator
- Principal Investigator
  
  北村正敬
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
Role of gap junction-mediated intercellular communication on schaemia/reperfusion renal injury
- Principal Investigator
  
  YAO Jian
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
Prevention of ulcerative colitis by cigarettesmoking: Development of a novel therapeutic strategy using genetically engineered micePrincipal Investigator
- Principal Investigator
  
  KITAMURA Masanori
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Yamanashi
Assessment of the lacrimal and ocular surface damage mechanism related to smoking
- Principal Investigator
  
  MURAT Dogru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Roles of ER stress in renal pathophysiology and development of novel therapeutic approaches to kidney diseasesPrincipal Investigator
- Principal Investigator
  
  KITAMURA Masanori
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
Role of intercellular communication in the control of renin secretion
- Principal Investigator
  
  YAO Jian
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
遺伝子組換えマウスを用いた喫煙および喫煙環境の総合的・継続的リスク評価Principal Investigator
- Principal Investigator
  
  北村正敬
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Yamanashi
トランスジェニックセンサーマウスを用いた環境パトロールシステムの構築Principal Investigator
- Principal Investigator
  
  北村正敬
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  University of Yamanashi
ギャップ結合を介した細胞間コミュニケーションの炎症性賢障害における役割
- Principal Investigator
  
  姚建
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
ギャップ結合を介した血管内皮細胞由来弛緩因子による傍糸球体細胞レニン分泌制御機構
- Principal Investigator
  
  田邉信明
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Development of in vivo biosensors using genetic engineeringPrincipal Investigator
- Principal Investigator
  
  KITAMURA Masanori
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
The mechanisms involved in the regulation of mmesangial cell phenotype by endothetial cells : role of gap junction
- Principal Investigator
  
  YAO Jian
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
幹細胞を用いた腎糸球体再生の試みPrincipal Investigator
- Principal Investigator
  
  北村正敬
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
  Jikei University School of Medicine

All 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

[Book] Annual Review腎臓(小胞体ストレストメサンギウムの細胞応答)2011
- Author(s)
  北村正敬
- Data Source
  KAKENHI-PROJECT-20390235
[Book] Methods in Enzymology(UPR and Cell Stress)(Real-time monitoring of ER stress in living cells and animals using ESTRAP assay)(Vol.490, Chaoter 5)2011
- Author(s)
  Kitamura M, Hiramatsu N
- Data Source
  KAKENHI-PROJECT-20390235
[Book] Methods in Enzymology (UPR and Cell Stress), Vol.490, Chapter 52011
- Author(s)
  Kitamura M, Hiramatsu N
- Total Pages
  14
- Publisher
  Real-time monitoring of ER stress in living cells and animalsusing ESTRAP assay
- Data Source
  KAKENHI-PROJECT-20390235
[Book] Methods in Enzymology(UPR and Cell Stress)Vol.490, Chapter 5: Real-time monitoring of ER stress in living cells and animals using ESTRAP assay.2011
- Author(s)
  Kitamura M, Hiramatsu N
- Publisher
  Academic Press(Elsevier)
- Data Source
  KAKENHI-PROJECT-22651020
[Book] Annual Review腎臓(Gap Junctionを介した細胞間情報伝達メサンギウム細胞の動態制御に於ける役割)2009
- Author(s)
  姚建、北村正敬
- Data Source
  KAKENHI-PROJECT-20390235
[Book] Annual Review腎臓(腎における小胞体ストレス(ER stress)の意義2008
- Author(s)
  北村正敬
- Data Source
  KAKENHI-PROJECT-20390235
[Book] Methods in Enzymology(UPR and Cell Stress)Vol. 490, Chapter 5 :Real-time monitornig of ER stress living cells and animals using ESTRAP assay.
- Author(s)
  Kitamura M, Hiramatsu N
- Publisher
  Academic Press(Elsevier)
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Pathological in situ reprogramming of somatic cells by the unfolded protein response2013
- Author(s)
  Johno H and Kitamura M
- Journal Title
  
  Am J Pathol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Dual regulation of cadmium-induced apoptosis by mTORC1 through selective induction of IRE1 branches in unfolded protein response2013
- Author(s)
  Kato H, Katoh R, and Kitamura M
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Pleiotropic potential of DHMEQ for NF-κB suppression via reactive oxygen species and unfolded protein response2013
- Author(s)
  Nakajima S, Kato H,Gu L, Takahashi S,Johno H, Umezawa K, and Kitamura M
- Journal Title
  
  J Immunol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] The unfolded protein response triggered by environmental factors2013
- Author(s)
  Kitamura M
- Journal Title
  
  Semin Immunopathol
  
  Volume: 35 Pages: 259-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Pleiotropic potential of DHMEQ for NF-κB suppression via reactive oxygen species and unfolded protein response2013
- Author(s)
  Nakajima S, Kato H,Gu L, Takahashi S,Johno H, Umezawa K, and Kitamura M
- Journal Title
  
  J Immuno
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Eviprostat activates cAMP signaling pathway and suppresses bladder smooth muscle cell proliferation2013
- Author(s)
  Li K, Yao J, Chi Y, Sawada N, Araki I, Kitamura M, and Takeda M
- Journal Title
  
  Int J Mol Sci
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Eviprostat activates cAMP signaling pathway and suppresses bladder smooth muscle cell proliferation2013
- Author(s)
  Li K, Yao J, Chi Y, Sawada N, Araki I, Kitamura M, and Takeda M
- Journal Title
  
  Int J Mol Sci
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Eviprostat activates cAMP signaling pathway and suppresses bladder smooth muscle cell proliferation2013
- Author(s)
  Li K, Yao J, Chi Y, Sawada N, Araki I, Kitamura M and Takeda M
- Journal Title
  
  Int J Mol Sci
  
  Volume: Vol.14, No.6 Issue: 6 Pages: 12107-12122
- DOI
  10.3390/ijms140612107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591187, KAKENHI-PROJECT-24592428
[Journal Article] Pathological in situ reprogramming of somatic cells by the unfolded protein response2013
- Author(s)
  Johno H and Kitamura M
- Journal Title
  
  Am J Pathol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Connexin43 hemichannel-mediated regulation of connexin432013
- Author(s)
  Li K, Chi Y, Gao K, Yan Q, Matsue H, Takeda T, Kitamura M, and Yao J
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 2 Pages: e58057-e58057
- DOI
  10.1371/journal.pone.0058057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-23390381, KAKENHI-PROJECT-23591187, KAKENHI-PROJECT-24592426
[Journal Article] Dual regulation of cadmium-induced apoptosis by mTORC1 through selective induction of IRE1 branches in unfolded protein response2013
- Author(s)
  Kato H, Katoh R, and Kitamura M
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 5 Pages: e64344-e64344
- DOI
  10.1371/journal.pone.0064344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-24790840
[Journal Article] Grape seed extract from "Koshu" cultivar antagonizes dioxin-induced aryl hydrocarbon receptor activation.2013
- Author(s)
  Sugiyama T, Kitamura M, Sugita K, Okuda T, Hisamoto M, and Nakao A
- Journal Title
  
  Am J Enol Viticult
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Grape seed extract from "Koshu" cultivar antagonizes dioxin-induced aryl hydrocarbon receptor activation2013
- Author(s)
  Sugiyama T, Kitamura M, Sugita K, Okuda T, Hisamoto M, and Nakao A
- Journal Title
  
  Am J Enol Viticult
  
  Volume: (in press) Issue: 1 Pages: 146-151
- DOI
  10.5344/ajev.2012.11131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-23659499
[Journal Article] Blockade of Smad signaling by 3 '-deoxyadenosine: a mechanism for its anti-fibrotic potential2013
- Author(s)
  Gu L, Johno H, Nakajima S, Kato H, Takahashi H, Katoh K, and Kitamura M
- Journal Title
  
  Lab Invest
  
  Volume: 93 Issue: 4 Pages: 450-461
- DOI
  10.1038/labinvest.2013.4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-22651020
[Journal Article] Connexin43 hemichannel-mediated regulation of connexin432013
- Author(s)
  Li K, Chi Y, Gao K, Yan Q, Matsue H, Takeda T, Kitamura M, and Yao J
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Intervention in genotoxic stress-induced senescence by cordycepin through activation of eIF2αand suppression of Sp12013
- Author(s)
  Gu L,Johno H, Nakajima S, Yoshitomi T, Takahashi S, and Kitamura M
- Journal Title
  
  Toxicol Sci
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Intervention in genotoxic stress-induced senescence by cordycepin through activation of eIF2αand suppression of Sp12013
- Author(s)
  Gu L,Johno H, Nakajima S, Yoshitomi T, Takahashi S, and Kitamura M
- Journal Title
  
  Toxicol Sci
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] he unfolded protein response triggered by environmental factors2013
- Author(s)
  Kitamura M
- Journal Title
  
  Semin Immunopathol
  
  Volume: 35 Issue: 3 Pages: 259-275
- DOI
  10.1007/s00281-013-0371-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Blockade of Smad signaling by 3 '-deoxyadenosine: a mechanism for its anti-fibrotic potential2013
- Author(s)
  Gu L, Johno H, Nakajima S, Kato H, Takahashi H, Katoh K, and Kitamura M
- Journal Title
  
  Lab Invest
  
  Volume: 93 Pages: 450-461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] NADPH oxidase-mediated upregulation of connexin43 contributes to podocyte injury2012
- Author(s)
  Yan Q, Gao K, Chi Y, Li K, Zhu Y, Wan Y,Sun W,Matsue H, Kitamura M, and Yao Y
- Journal Title
  
  Free Rad Biol Med
  
  Volume: 53 Issue: 6 Pages: 1286-1297
- DOI
  10.1016/j.freeradbiomed.2012.07.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-23591187
[Journal Article] Sensitive detection and monitoring of senescence-associated secretory phenotype by SASP-RAP assay2012
- Author(s)
  Gu L, and Kitamura M
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Cordycepin as a sensitizer to TNF-α-induced apoptosis through eIF2α- and mTORC1- mediated inhibition of NF-κB2012
- Author(s)
  Kadomatsu M, Nakajima S, Kato H, Gu L, Chi Y, Yao J and Kitamura M
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 168 Pages: 325-332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Acidic stress-ER stress axis for blunted activation of NF-κB in mesothelial cells exposed to peritoneal dialysis fluid2012
- Author(s)
  Johno H, Ogata R, Nakajima S, Hiramatsu N, Kobayashi T, Hara H, and Kitamura M
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 27 Pages: 4053-4060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] β-catenin signaling contributes to PDGF-elicited bladder smooth muscle cell contraction through up-regulation of Cx43 expression2012
- Author(s)
  Li K, Yao J, Sawada N, Kitamura M, Andersson K-E, and Takeda M
- Journal Title
  
  J Urol
  
  Volume: 188 Issue: 1 Pages: 307-332
- DOI
  10.1016/j.juro.2012.02.2556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-23591187, KAKENHI-PROJECT-23659754, KAKENHI-PROJECT-24592426
[Journal Article] Blockade of adipocyte differentiation by cordycepin2012
- Author(s)
  Takahashi S, Tamai T, Nakajima S, Kato H, Johno H, Nakamura T, and Kitamura M
- Journal Title
  
  British J Pharmacol
  
  Volume: 167 Pages: 561-575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway2012
- Author(s)
  Kato H, Nakajima S, Saito Y, Takahashi S, Katoh R, and Kitamura M
- Journal Title
  
  Cell Death Differ
  
  Volume: 19 Pages: 310-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] β-catenin signaling contributes to PDGF-elicited bladder smooth muscle cell contraction through up-regulation of Cx43 expression2012
- Author(s)
  Li K, Yao J, Sawada N, Kitamura M, Andersson K-E, and Takeda M
- Journal Title
  
  J Urol
  
  Volume: 188 Pages: 307-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Blockade of adipocyte differentiation by cordycepin2012
- Author(s)
  Takahashi S, Tamai T, Nakajima S, Kato H, Johno H, Nakamura T, and Kitamura M
- Journal Title
  
  British J Pharmacol
  
  Volume: 167 Issue: 3 Pages: 561-575
- DOI
  10.1111/j.1476-5381.2012.02005.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-24790840
[Journal Article] mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway2012
- Author(s)
  Kato H, Nakajima S, Saito Y, Takahashi S, Katoh R, and Kitamura M
- Journal Title
  
  Cell Death Differ
  
  Volume: 19 Issue: 2 Pages: 310-320
- DOI
  10.1038/cdd.2011.98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-24790840
[Journal Article] Unfolded protein response causes a phenotypic shift of inflamed glomerular cells towards redifferentiation through dual blockade of Akt and Smad signaling pathways2012
- Author(s)
  Johno H, Nakajima S,Kato H,Yao J, Paton AW, Paton JC, Katoh R, Shimizu F, and Kitamura M
- Journal Title
  
  Am J Pathol
  
  Volume: 181 Issue: 6 Pages: 1977-1990
- DOI
  10.1016/j.ajpath.2012.08.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-23591187, KAKENHI-PROJECT-24790840
[Journal Article] Cordycepin as a sensitizer to TNF-α- induced apoptosis through eIF2α- and mTORC1- mediated inhibition of NF-κB2012
- Author(s)
  Kadomatsu M, Nakajima S, Kato H, Gu L, Chi Y, Yao J and Kitamura M
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 168 Issue: 3 Pages: 325-332
- DOI
  10.1111/j.1365-2249.2012.04580.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-23591187, KAKENHI-PROJECT-24790840
[Journal Article] Sensitive detection and monitoring of senescence-associated secretory phenotype by SASP-RAP assay2012
- Author(s)
  Gu L, and Kitamura M
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 12 Pages: e52305-e52305
- DOI
  10.1371/journal.pone.0052305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-22651020
[Journal Article] Acidic stress - ER stress axis for blunted activation of NF-κB in mesothelial cells exposed to peritoneal dialysis fluid2012
- Author(s)
  Johno H, Ogata R, Nakajima S, Hiramatsu N, Kobayashi T, Hara H, and Kitamura M
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 27 Issue: 11 Pages: 4053-4060
- DOI
  10.1093/ndt/gfs130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-22651020
[Journal Article] NADPH oxidase-mediated upregulation of connexin43 contributes to podocyte injury2012
- Author(s)
  Yan Q, Gao K, Chi Y, Li K, Zhu Y, Wan Y,Sun W,Matsue H, Kitamura M, and Yao Y
- Journal Title
  
  Free Rad Biol Med
  
  Volume: 53 Pages: 1286-1297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Unfolded protein response causes a phenotypic shift of inflamed glomerular cells towards redifferentiation through dual blockade of Akt and Smad signaling pathways2012
- Author(s)
  Johno H, Nakajima S,Kato H,Yao J, Paton AW, Paton JC, Katoh R, Shimizu F, and Kitamura M
- Journal Title
  
  Am J Pathol
  
  Volume: 181 Pages: 1977-1990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Aryl hydrocarbon receptor 経路4の活性化によるデキストラン硫酸ナトリウム誘導性大腸炎の抑制2011
- Author(s)
  高村武之、原間大輔、下川直美、北村正敬、中尾篤人
- Journal Title
  
  消化器と免疫
  
  Volume: 47 Pages: 76-79
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Control of NF-κB and inflammation by the unfolded protein response2011
- Author(s)
  Kitamura M
- Journal Title
  
  Int Rev Immunol
  
  Volume: 30 Issue: 1 Pages: 4-15
- DOI
  10.3109/08830185.2010.522281
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] 小胞体ストレスとメサンギウムの細胞応答2011
- Author(s)
  北村正敬
- Journal Title
  
  Annual Review 腎臓
  
  Pages: 30-37
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Connexin43 hemichannels contribute to cadmium- induced oxidative stress and cell injury2011
- Author(s)
  Fang X, Huang T, ZhuY, Jiang JX, Wang P, Kitamura Mand Yao J
- Journal Title
  
  Antioxid Redox Signal
  
  Volume: 14 Issue: 12 Pages: 2427-2439
- DOI
  10.1089/ars.2010.3150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-21390324
[Journal Article] Induction of CCAAT/enhancer-binding protein-homologous protein by cigarette smoke through the superoxide anion- triggered PERK - eIF2αpathway2011
- Author(s)
  Tagawa Y, Hiramatsu N, Kato H, Sakoh T, Nakajima S, Hayakawa K, Saito Y, Johno H, Takahashi S, Gu L, Yao J, and Kitamura M
- Journal Title
  
  Toxicology
  
  Volume: 287 Issue: 1-3 Pages: 105-112
- DOI
  10.1016/j.tox.2011.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Inhibition of NF-κB by MG132 through ER stress-mediated induction of LAP and LIP2011
- Author(s)
  Nakajima S, Kato H, Takahashi S, Johno H, and Kitamura M
- Journal Title
  
  FEBS Lett
  
  Volume: 585 Issue: 14 Pages: 2249-2254
- DOI
  10.1016/j.febslet.2011.05.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] 小胞体ストレスとメサンギウムの細胞応答2011
- Author(s)
  北村正敬
- Journal Title
  
  Annual Review 腎臓
  
  Pages: 30-37
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Impairment of MCP-1 expression in mesothelial cells exposed to PDF by osmotic stress and acidic stress2011
- Author(s)
  Ogata R, Hiramatsu N, Hayakawa K, Nakajima S, Yao J, Kobayashi T, and Kitamura M
- Journal Title
  
  Perit Dial Int
  
  Volume: 31 Issue: 1 Pages: 80-89
- DOI
  10.3747/pdi.2009.00159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Control of NF-κB and inflammation by the unfolded protein response2011
- Author(s)
  Kitamura M
- Journal Title
  
  Int Rev Immunol
  
  Volume: 30 Pages: 4-15
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Cytoprotective roles of ERK and Akt in endoplasmic reticulum stress triggered by subtilase cytotoxin.2011
- Author(s)
  Tian T, Zhao Y, Nakajima S, Huang T, Yao J, Paton AW, Paton JC and Kitamura M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 410 Pages: 852-858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Reciprocal regulation between proinflammatory cytokine-induced iNOS and connexin43 in bladder smooth muscle cells2011
- Author(s)
  Li K, Yao J, Shi L, Sawada N, Chi Y, Yan Q, Fukayama M, Zakohji H, Araki I, Kitamura Mand Takeda M
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Issue: 48 Pages: 41552-41562
- DOI
  10.1074/jbc.m111.274449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-21390324, KAKENHI-PROJECT-23591187
[Journal Article] Selective abrogation of BiP/GRP78 blunts activation of NF-kB through the ATF6 branch of the UPR : involvement of C/EBP β and mTOR-dependent dephosphorylation of Akt.2011
- Author(s)
  Nakajima S, Hiramatsu N, Hayakawa K, Saito Y, Kato H, Huang T, Yao J, Paton AW, Paton JC, Kitamura M
- Journal Title
  
  Mol Cell Biol 31
  
  Pages: 1710-1718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Dysfunction of corneas and lacrimal glands in smoking model rat2011
- Author(s)
  Higuchi A, Ito K, Dogru M, Kitamura M, Kawakita T, Ogawa Y, and Tsubota K
- Journal Title
  
  Free Rad Biol Med
  
  Volume: 51 Pages: 2210-2216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Subtilase cytotoxin activates MAP kinases through PERK and IRE1 branches of the unfolded protein response2011
- Author(s)
  Zhao Y,Tian T, Huang T,Nakajima S, Saito Y, Takahashi S, Yao J, Paton AW, PatonJC, and Kitamura M
- Journal Title
  
  Toxicol Sci
  
  Volume: 120 Pages: 79-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Corneal damage and lacrimal gland dysfunction in a smoking rat model2011
- Author(s)
  Higuchi A, Ito K, Dogru M, Kitamura M, Mitani F, Kawakita T, Ogawa Y, Tsubota K
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: Vol.51 Pages: 2210-2216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592244
[Journal Article] Selective abrogation of BiP/GRP78 blunts activation of NF-κB through the ATF6 branch of the UPR: involvement of C/EBPβand mTOR-dependent dephosphorylation of Akt2011
- Author(s)
  Nakajima S, HiramatsuN, Hayakawa K, Saito Y, Kato H, Huang T, Yao J, Paton AW, Paton JC, and Kitamura M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31 Issue: 8 Pages: 1710-1718
- DOI
  10.1128/mcb.00939-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-22390098
[Journal Article] Real-time monitoring of ER stress in living cells and animals using ESTRAP assay2011
- Author(s)
  Kitamura M, and Hiramatsu N
- Journal Title
  
  Methods in Enzymology(UPR and Cell Stress
  
  Volume: Chapter 5
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Lactobacillus bulgaricusOLL1181 activates the aryl hydrocarbon receptor pathway and inhibits colitis2011
- Author(s)
  Takamura T, Harama D, Fukumoto S, Nakamura Y, Shimokawa N, Ohshima K, Ikegami S, Makino S, Kitamura M, and Nakao A
- Journal Title
  
  Immunol Cell Bioll
  
  Volume: 89 Issue: 7 Pages: 817-822
- DOI
  10.1038/icb.2010.165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-22651020
[Journal Article] Nonsteroidal anti- inflammatory drug flufenamic acid is a potent activator of AMPK2011
- Author(s)
  Chi Y, Li K, Yan Q, Koizumi S, Shi L, Takahashi S, Zhu Y, Matsue H, Takeda M, Kitamura M, Yao J
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 339 Pages: 257-266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Lactobacillus bulgaricusOLL1181 activates the aryl hydrocarbon receptor pathway and inhibits colitis.2011
- Author(s)
  Takamura T, Harama D, Fukumoto S, Nakamura Y, Shimokawa N, Ohshima K, Ikegami S, Makino S, Kitamura M, and Nakao A
- Journal Title
  
  Immunol Cell Bioll
  
  Volume: 89 Pages: 817-822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Aryl hydrocarbon receptor 経路の活性化によるデキストラン硫酸ナトリウム誘導性大腸炎の抑制2011
- Author(s)
  高村武之、原間大輔、下川直美、北村正敬、中尾篤人
- Journal Title
  
  消化器と免疫
  
  Volume: 47 Pages: 76-79
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Inhibition of NF-κB by MG132 through ER stress-mediated induction of LAP and LIP2011
- Author(s)
  Nakajima S, Kato H, Takahashi S, Johno H, and Kitamura M
- Journal Title
  
  FEBS Lett
  
  Volume: 585 Pages: 2249-2254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Impairment of MCP-1 expression in mesothelial cells exposed to PDF by osmotic stress and acidic stress.2011
- Author(s)
  Ogata R, Hiramatsu N, Hayakawa K, Nakajima S, Yao J, Kobayashi T, Kitamura M
- Journal Title
  
  Perit Dial Int 31
  
  Pages: 80-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Oscillation of mitogen- activated protein kinases in response to endoplasmic reticulum stress2011
- Author(s)
  Zhang H, Zhao Y,TianT, Paton AW, Paton JC, Kitamura M
- Journal Title
  
  Anal Biochem
  
  Volume: 417 Pages: 292-294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Subtilase cytotoxin activates MAP kinases through PERK and IRE1 branches of the unfolded protein response2011
- Author(s)
  Zhao Y,Tian T, Huang T,Nakajima S, Saito Y, Takahashi S, Yao J, Paton AW, PatonJC, and Kitamura M
- Journal Title
  
  Toxicol Sci
  
  Volume: 120 Issue: 1 Pages: 79-86
- DOI
  10.1093/toxsci/kfq368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Selective abrogation of BiP/GRP78 blunts activation of NF-κB through the ATF6 branch of the UPR: involvement of C/EBPβand mTOR- dependent dephosphorylation of Akt2011
- Author(s)
  Nakajima S, HiramatsuN, Hayakawa K, Saito Y, Kato H, Huang T, Yao J, Paton AW, Paton JC, and Kitamura M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31 Pages: 1710-1718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Cytoprotective roles of ERK and Akt in endoplasmic reticulum stress triggered by subtilase cytotoxin2011
- Author(s)
  Tian T, Zhao Y, Nakajima S, Huang T, Yao J, Paton AW, Paton JC and Kitamura M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 410 Issue: 4 Pages: 852-858
- DOI
  10.1016/j.bbrc.2011.06.078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Induction of CCAAT/enhancer-binding protein-homologous protein by cigarette smoke through the superoxide anion-triggered PERK - eIF2αpathway2011
- Author(s)
  Tagawa Y, Hiramatsu N, Kato H, Sakoh T, Nakajima S, Hayakawa K, Saito Y, Johno H, Takahashi S, Gu L, Yao J, and Kitamura M
- Journal Title
  
  Toxicology
  
  Volume: 287 Pages: 105-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Nonsteroidal anti-inflammatory drug flufenamic acid is a potent activator of AMPK2011
- Author(s)
  Chi Y, Li K, Yan Q, Koizumi S, Shi L, Takahashi S, Zhu Y, Matsue H, Takeda M, Kitamura M, Yao J
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 339 Issue: 1 Pages: 257-266
- DOI
  10.1124/jpet.111.183020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-21390324, KAKENHI-PROJECT-23591187
[Journal Article] Impairment of MCP-1 expression in mesothelial cells exposed to PDF by osmotic stress and acidic stress2011
- Author(s)
  Ogata R, Hiramatsu N, Hayakawa K, Nakajima S, Yao J, Kobayashi T, and Kitamura M
- Journal Title
  
  Perit Dial Int
  
  Volume: 31 Pages: 80-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Dysfunction of corneas and lacrimal glands in smoking model rat2011
- Author(s)
  Higuchi A, Ito K, Dogru M, Kitamura M, Kawakita T, Ogawa Y, and Tsubota K
- Journal Title
  
  Free Rad Biol Med
  
  Volume: 51 Issue: 12 Pages: 2210-2216
- DOI
  10.1016/j.freeradbiomed.2011.09.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-23592590
[Journal Article] Aberrant, differential and bidirectional regulation of the unfolded protein response towards cell survival by 3'-deoxyadenosine2011
- Author(s)
  Kitamura M, Kato H, Saito Y, Nakajima S, Takahashi S, Johno H, Gu L, and Katoh R
- Journal Title
  
  Cell Death Differ
  
  Volume: 18 Pages: 1876-1888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Connexin43 hemichannels contribute to cadmium-induced oxidative stress and cell injury.2011
- Author(s)
  Fang X, Huang T, Zhu Y, Jiang JX, Wang P, Kitamura M, Yao J
- Journal Title
  
  Antioxid Redox Signal 15 14
  
  Pages: 2427-2439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Selective abrogation of BiP/GRP78 blunts activation of NF-κB through the ATF6 branch of the UPR : involvement of C/EBPβand mTOR-dependent dephosphorylation of Akt.2011
- Author(s)
  Nakajima S, Hiramatsu N, Hayakawa K, Saito Y, Kato H, Huang T, Yao J Paton AW, Paton JC, Kitamura M
- Journal Title
  
  Mol Cell Biol 31
  
  Pages: 1710-1718
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Oscillation of mitogen-activated protein kinases in response to endoplasmic reticulum stress2011
- Author(s)
  Zhang H, Zhao Y,TianT, Paton AW, Paton JC, Kitamura M
- Journal Title
  
  Anal Biochem
  
  Volume: 417 Issue: 2 Pages: 292-294
- DOI
  10.1016/j.ab.2011.06.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Real-time monitoring of ER stress in living cells and animals using ESTRAP assay2011
- Author(s)
  Kitamura M, and Hiramatsu N
- Journal Title
  
  Methods in Enzymology(UPR and Cell Stress)
  
  Volume: Vol. 490, Chapter 5 Pages: 93-106
- DOI
  10.1016/b978-0-12-385114-7.00005-2
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Aberrant, differential and bidirectional regulation of the unfolded protein response towards cell survival by 3'-deoxyadenosine2011
- Author(s)
  Kitamura M, Kato H, Saito Y, Nakajima S, Takahashi S, Johno H, Gu L, and Katoh R
- Journal Title
  
  Cell Death Differ
  
  Volume: 18 Issue: 12 Pages: 1876-1888
- DOI
  10.1038/cdd.2011.63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Reciprocal regulation between proinflammatory cytokine-induced iNOS and connexin43 in bladder smooth muscle cells2011
- Author(s)
  Li K, Yao J, Shi L, Sawada N, Chi Y, Yan Q, Fukayama M, Zakohji H, Araki I, Kitamura Mand Takeda M
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 41552-41562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Selective deletion of adipocytes, but not preadipocytes, by TNF-α via C/EBP- and PPARγ-mediated suppression of NF-κB2010
- Author(s)
  Tamai M, Shimada T, Hiramatsu N, Hayakawa K, Okamura M, Tagawa Y, Takahashi S, Nakajima S, Yao J, and Kitamura M
- Journal Title
  
  Lab Invest
  
  Volume: 90 Issue: 9 Pages: 1385-1395
- DOI
  10.1038/labinvest.2010.118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Gap junctions sensitize cancer cells to proteasome inhibitor MG132-induced apoptosis2010
- Author(s)
  Huang T, Zhu Y, Fang X, Chi Y, Kitamura M, and Yao J
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 713-721
- NAID
  10026589655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Induction of the unfolded protein response by calcineurin inhibitors: A double-edged sword in renal transplantation2010
- Author(s)
  Kitamura M
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 25 Issue: 1 Pages: 6-9
- DOI
  10.1093/ndt/gfp516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Disruption of gap junction attenuates aminoglycoside- elicited renal tubular cell injury2010
- Author(s)
  Yao J, Huang T, Fang X, Chi Y, Zhu Y, Wan Y, Matsue H, and Kitamura M
- Journal Title
  
  Br J Pharmacol
  
  Volume: 160 Pages: 2055-2068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Activation of the arylhydrocarbon receptor pathway may ameliorate dextran sodium sulfate-induced colitis in mice2010
- Author(s)
  Takamura T, Harama D, Matsuoka S, Shimokawa N, Nakamura Y, Okumura K, Ogawa H, Kitamura M, and Nakao A
- Journal Title
  
  Immunol Cell Biol
  
  Volume: 88 Issue: 6 Pages: 685-689
- DOI
  10.1038/icb.2010.35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Connexin43 hemichannels contribute to cadmium-induced oxidative stress and cell injury2010
- Author(s)
  Fang X, Huang T, ZhuY, Jiang JX, Wang P, Kitamura M and Yao J
- Journal Title
  
  Antioxid Redox Signal
  
  Volume: 14 Pages: 2427-2439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Suppression of nephrin expression by TNF-α via interfering with the cAMP - retinoic acid receptor pathway2010
- Author(s)
  Saito Y, Okamura M, Nakajima S, Hayakawa K, Huang T, Yao J, and Kitamura M
- Journal Title
  
  Am J Physiol-Renal
  
  Volume: 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Influences of acidic conditions on formazan assay: A cautionary note2010
- Author(s)
  Johno H, Takahashi S, and Kitamura M
- Journal Title
  
  Appl Biochem Biotech
  
  Volume: 162 Issue: 6 Pages: 1529-1535
- DOI
  10.1007/s12010-010-8934-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Influences of acidic conditions on formazan assay: A cautionary note.2010
- Author(s)
  Johno H, Takahashi S, and Kitamura M
- Journal Title
  
  Appl Biochem Biotech
  
  Volume: 162 Pages: 1529-1535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] The oxidative stress - endoplasmic reticulum stress axis in cadmium toxicity2010
- Author(s)
  Kitamura M, and Hiramatsu N
- Journal Title
  
  Biometals
  
  Volume: 23 Pages: 941-950
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] ER stress depresses NF-κB activation in mesangial cells through preferential induction of C/EBPβ2010
- Author(s)
  Hayakawa K, Nakajima S, Hiramatsu N, Okamura M, Huang T, Saito Y, Tagawa Y, Tamai M, Takahashi S, Yao J, and Kitamura M
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 21 Issue: 1 Pages: 73-81
- DOI
  10.1681/asn.2009040432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] ER stress depresses NF-κB activation in mesangial cells through preferential induction of C/EBPβ.2010
- Author(s)
  Hayakawa K, Nakajima S, Hiramatsu N, Okamura M, Huang T, Saito Y, Tagawa Y, Tamai M, Takahashi S, Yao J, and Kitamura M
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 21 Pages: 73-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Anti- inflammatory subtilase cytotoxin up-regulates A20 through the unfolded protein response2010
- Author(s)
  Nakajima S,Saito Y, Takahashi S, Hiramatsu N, Kato H,Johno H, Yao J,Paton AW, Paton JC, and Kitamura M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 397 Pages: 176-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Anti-inflammatory subtilase cytotoxin up-regulates A20 through the unfolded protein response2010
- Author(s)
  Nakajima S,Saito Y, Takahashi S, Hiramatsu N, Kato H,Johno H, Yao J, Paton AW, Paton JC, and Kitamura M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 397 Issue: 2 Pages: 176-180
- DOI
  10.1016/j.bbrc.2010.05.069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] ER stress depresses NF-κB activation in mesangial cells through preferential induction of C/EBPβ.2010
- Author(s)
  Hayakawa K, Nakajima S, Hiramatsu N, Okamura M, Huang T, Saito Y, Tagawa Y, Tamai M, Takahashi S, YaoJ, Kitamura M
- Journal Title
  
  J Am Soc Nephrol 21
  
  Pages: 73-81
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Selective deletion of adipocytes, but not preadipocytes, by TNF-α via C/EBP- and PPARγ-mediated suppression of NF-κB.2010
- Author(s)
  Tamai M, Shimada T, Hiramatsu N, Hayakawa K, Okamura M, Tagawa Y, Takahashi S, Nakajima S, Yao J, Kitamura M
- Journal Title
  
  Lab Invest 90
  
  Pages: 1385-1395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Gap junctions sensitize cancer cells to proteasome inhibitor MG132-induced apoptosis2010
- Author(s)
  Huang T, Zhu Y, Fang X, Chi Y, Kitamura M, and Yao J
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Issue: 3 Pages: 716-721
- DOI
  10.1111/j.1349-7006.2009.01421.x
- NAID
  10026589655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Anti-inflammatory subtilase cytotoxin up-regulates A20 through the unfolded protein response.2010
- Author(s)
  Nakajima S, Saito Y, Takahashi S, Hiramatsu N, Kato H, Johno H, Yao J, Paton AW, Paton JC, Kitamura M
- Journal Title
  
  Biochem Biophys Res Commun 397
  
  Pages: 176-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Suppression of nephrin expression by TNF-α via interfering with the cAMP - retinoic acid receptor pathway2010
- Author(s)
  Saito Y, Okamura M, Nakajima S, Hayakawa K, Huang T, Yao J, and Kitamura M
- Journal Title
  
  Am J Physiol-Renal
  
  Volume: 298 Issue: 6 Pages: F1436-F1444
- DOI
  10.1152/ajprenal.00512.2009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Activation of the arylhydrocarbon receptor pathway may ameliorate dextran sodium sulfate-induced colitis in mice2010
- Author(s)
  Takamura T, Harama D, Matsuoka S, Shimokawa N, Nakamura Y, Okumura K, Ogawa H, Kitamura M, and Nakao A
- Journal Title
  
  Immunol Cell Biol
  
  Volume: 88 Pages: 685-689
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Selective deletion of adipocytes, but not preadipocytes, by TNF-α via C/EBP- and PPARγ-mediated suppression of NF-κB2010
- Author(s)
  Tamai M, Shimada T, Hiramatsu N, Hayakawa K, Okamura M, Tagawa Y, Takahashi S, Nakajima S, Yao S, and Kitamura M:
- Journal Title
  
  Lab Invest
  
  Volume: 90 Pages: 1385-1395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Disruption of gap junction attenuates aminoglycoside-elicited renal tubular cell injury.2010
- Author(s)
  Yao J, Huang T, Fang X, Chi Y, Zhu Y, Wan Y, Matsue H, Kitamura M
- Journal Title
  
  Br J Pharmacol 160
  
  Pages: 2055-2068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Gap junctions sensitize cancer cells to proteasome inhibitor MG132-induced apoptosis.2010
- Author(s)
  Huang T, Zhu Y, Fang X, Chi Y, Kitamura M, Yao J
- Journal Title
  
  Cancer Sci 101
  
  Pages: 713-721
- NAID
  10026589655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Disruption of gap junction attenuates aminoglycoside- elicited renal tubular cell injury2010
- Author(s)
  Yao J, Huang T, Fang X, Chi Y, Zhu Y, Wan Y, Matsue H, and Kitamura M
- Journal Title
  
  Br J Pharmacol
  
  Volume: 160 Issue: 8 Pages: 2055-2068
- DOI
  10.1111/j.1476-5381.2010.00860.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-21390324
[Journal Article] Induction of the unfolded protein response by calcineurin inhibitors: A double-edged sword in renal transplantation.2010
- Author(s)
  Kitamura M
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 25 Pages: 6-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22651020
[Journal Article] Suppression of NF-κB by cyclosporine A and tacrolimus (FK506) via induction of the C/EBP family : Implication for unfolded protein response.2009
- Author(s)
  Du S, Hiramatsu N, Hayakawa K, Kasai A, Okamura M, Huang T, Yao J, Takeda M, Araki I, Sawada N, Paton AW, Paton JC, Kitamura M
- Journal Title
  
  J Immunol 182
  
  Pages: 7201-7211
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Activation of the Akt - NF-κB pathway by subtilase cytotoxin through the ATF6 branch of the unfolded protein response2009
- Author(s)
  YamazakiH, Hiramatsu N, Hayakawa K, Tagawa Y, Okamura M, Ogata R, Huang T,Nakajima S, Yao J, Paton AW, Paton JC, andKitamura M
- Journal Title
  
  J Immunol
  
  Volume: 183 Issue: 2 Pages: 1480-1487
- DOI
  10.4049/jimmunol.0900017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Downregulation of gap junction expression and function by endoplasmic reticulum stress.2009
- Author(s)
  Huang T, Wan Y, Zhu Y, Fang X, Hiramatsu N, Hayakawa K, Paton A, Paton J, Kitamura M, Yao J
- Journal Title
  
  J Cell Biochem 107
  
  Pages: 973-983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] A sub-cytotoxic dose of subtilase cytotoxin prevents LPS-induced inflammatory responses, depending on its capacity to induce the unfolded protein response.2009
- Author(s)
  Harama D, Koyama K, Mukai M, Shimokawa N, Miyata M, Nakamura Y, Ohnuma Y, Ogawa H, Matsuoka S, Paton AW, Paton JC, Kitamura M, Nakao A
- Journal Title
  
  J Immunol 183
  
  Pages: 1368-1374
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Acquisition of anergy to proinflammatory cytokines in non-immune cells through endoplasmic reticulum stress response : A mechanism for subsidence of inflammation.2009
- Author(s)
  Hayakawa K, Hiramatsu N, Okamura M, Yamazaki H, Nakajima S, YaoJ, Paton AW, Paton JC, Kitamura M
- Journal Title
  
  J Immunol 182
  
  Pages: 1182-1191
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] A sub-cytotoxic dose of subtilase cytotoxin prevents LPS-induced inflammatory responses, depending on its capacity to induce the unfolded protein response2009
- Author(s)
  Harama D, Koyama K, Mukai M, Shimokawa N, Miyata M, Nakamura Y, Ohnuma Y,Ogawa H,Matsuoka S, Paton AW,Paton JC, Kitamura M,and Nakao A
- Journal Title
  
  Immunol
  
  Volume: 183 Issue: 2 Pages: 1368-1374
- DOI
  10.4049/jimmunol.0804066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Dual suppression of adipogenesis by cigarette smoke through activation of the aryl hydrocarbon receptor and induction of endoplasmic reticulum stress2009
- Author(s)
  Shimada T, Hiramatsu N, Hayakawa K, Takahashi S, Kasai A, Tagawa Y, Mukai M, Yao J, Fujii-Kuriyama Y, and Kitamura M
- Journal Title
  
  Am J Physiol-Endocrinol and Metab
  
  Volume: 296 Issue: 4 Pages: E721-E730
- DOI
  10.1152/ajpendo.90829.2008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Suppression of NF-κB by cyclosporine A and tacrolimus (FK506) via induction of the C/EBP family: Implication for unfolded protein response2009
- Author(s)
  Du S, Hiramatsu N, Hayakawa K, Kasai A, Okamura M, Huang T, Yao J, Takeda M, Araki I, Sawada N, Paton AW, Paton JC, and KitamuraM
- Journal Title
  
  J Immunol
  
  Volume: 182 Issue: 11 Pages: 7201-7211
- DOI
  10.4049/jimmunol.0801772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-21592068
[Journal Article] Downregulation of gap junction expression and function by endoplasmic reticulum stress2009
- Author(s)
  Huang T, Wan Y, Zhu Y, Fang X, Hiramatsu N, Hayakawa K, Paton A, Paton J, Kitamura M, and Yao J
- Journal Title
  
  J Cell Biochem
  
  Volume: 107 Issue: 5 Pages: 973-983
- DOI
  10.1002/jcb.22202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Preferential blockade of dioxin-induced activation of the aryl hydrocarbon receptor by Antrodia camphorata2009
- Author(s)
  Mukai M, Hayakawa K, Okamura M, Tagawa Y, Nakajima S, Saito Y, Takahashi S, Yao J, Nishimura D, Sugi M, Matsunaga M, and Kitamura M
- Journal Title
  
  Biol Pharm Bull32
  
  Volume: 32 Pages: 1510-1515
- NAID
  130000117275
- URL
  https://www.jstage.jst.go.jp/article/bpb/32/9/32_9_1510/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Gap junctional intercellular communication in the juxtaglomerular apparatus2009
- Author(s)
  Yao J, Oite T and Kitamura M
- Journal Title
  
  Am J Physiol - Renal
  
  Volume: 296 Issue: 5 Pages: F939-F946
- DOI
  10.1152/ajprenal.90612.2008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Induction of nephrin gene expression by selective cooperation of the retinoic acid receptor and the vitamin D receptor2009
- Author(s)
  Okamura M, Takano Y, Saito Y, Yao J, and Kitamura M
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 24 Issue: 5 Pages: 3006-3012
- DOI
  10.1152/ajprenal.00602.2007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Endoplasmic reticulum stress in glomerulonephritis: The bad guy turns good?2009
- Author(s)
  Kitamura M
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 20 Issue: 9 Pages: 1871-1873
- DOI
  10.1089/ars.2008.2391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Acquisition of anergy to proinflammatory cytokines in non-immune cells through endoplasmic reticulum stress response: A mechanism for subsidence of inflammation2009
- Author(s)
  Hayakawa K, Hiramatsu N, Okamura M, Yamazaki H, Nakajima S, Yao J, Paton AW, Paton JC, and Kitamura M
- Journal Title
  
  J Immunol
  
  Volume: 182 Pages: 1182-1191
- URL
  http://www.jimmunol.org/content/182/2/1182.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Gap Junction を介した細胞間情報伝達:メサンギウム細胞の動態制御に於ける役割2009
- Author(s)
  姚建、北村正敬
- Journal Title
  
  Annual Review 腎臓
  
  Pages: 14-19
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Gap junctional intercellular communication in the juxtaglomerular apparatus.2009
- Author(s)
  Yao J, Oite T, Kitamura M
- Journal Title
  
  Am J Physiol - Renal 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Blockade of the aryl hydrocarbon receptor pathway triggered by dioxin, polycyclic aromatic hydrocarbons and cigarette smoke by Phellinus linteus2008
- Author(s)
  Mukai M, Kasai A, Hiramatsu N, Hayakawa K, Okamura M, Tagawa Y, Yao J, Nakamura T, and Kitamura M
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 31 Pages: 1888-1893
- NAID
  110006936328
- URL
  https://www.jstage.jst.go.jp/article/bpb/31/10/31_10_1888/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response2008
- Author(s)
  Yokouchi M, Hiramatsu N, Hayakawa K, Okamura M, Du S, Kasai A, Takano Y, Shitamura A, Shimada T, Yao J, and Kitamura M
- Journal Title
  
  J Biol Chem
  
  Volume: 283 Pages: 4252-4260
- URL
  http://www.jbc.org/content/283/7/4252.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response2008
- Author(s)
  Yokouchi, M., Hiramatsu, N., Hayakawa, K., Okamura, M., Du, S., Kasai, A., Takano, Y., Shitamura, A., Shimada, T., Yao, J., Kitamura, M
- Journal Title
  
  J Biol Chem 283
  
  Pages: 4252-4260
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Blockade of the dioxin pathway by herbal medicine Formula bupleuri minor: Identification of active entities for suppression of AhR activation2008
- Author(s)
  Kasai A, Hiramatsu N, Hayakawa K, Yao J, and Kitamura M
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 31 Pages: 838-846
- NAID
  110006663938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Endoplasmic reticulum stress in the kidney2008
- Author(s)
  Kitamura M
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 12 Issue: 5 Pages: 317-325
- DOI
  10.1007/s10157-008-0060-7
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Direct, continuous monitoring of air pollution by transgenic sensor mice responsive to halogenated and polycyclic aromatic hydrocarbons2008
- Author(s)
  Kasai A, Hiramatsu N, Hayakawa K, Yao J, and Kitamura M
- Journal Title
  
  Environ Health Perspect
  
  Volume: 116 Issue: 3 Pages: 349-354
- DOI
  10.1289/ehp.10722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response.2008
- Author(s)
  Yokouchi M, Hiramatsu N, Hayakawa K, Okamura M, Du S, Kasai A, Takano Y, Shitamura A, Shimada T, Yao J, Kitamura M
- Journal Title
  
  J Biol Chem 283
  
  Pages: 4252-4260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] 糸球体メサンギウム細胞の細胞特性2008
- Author(s)
  姚建、北村正敬、追手巌
- Journal Title
  
  日本腎臓学会誌 50
  
  Pages: 554-560
- NAID
  10024900768
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Induction of apoptosis by cigarette smoke via ROS-dependent endoplasmic reticulum stress and CCAAT/enhancer-binding protein-homologous protein (CHOP)2008
- Author(s)
  Tagawa Y, Hiramatsu N, Kasai A, Hayakawa K, Okamura M, Yao J, and Kitamura M
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 45 Issue: 1 Pages: 50-59
- DOI
  10.1016/j.freeradbiomed.2008.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] 腎における小胞体ストレス(ER stress)の意義2008
- Author(s)
  北村正敬
- Journal Title
  
  Annual Review 腎臓
  
  Pages: 22-30
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Suppression of adipocyte differentiation by Cordyceps militaris through activation of the aryl hydrocarbon receptor.2008
- Author(s)
  Shimada T, Hiramatsu N, Kasai A, Mukai M, Okamura M, Yao J, Huang T, Tamai M, Takahashi S, Nakamura T, and Kitamura M
- Journal Title
  
  Am J Physiol-Endocrinol and Metab
  
  Volume: 295 Issue: 4 Pages: E859-E867
- DOI
  10.1152/ajpendo.90373.2008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Direct, continuous monitoring of air pollution by transgenic sensor mice responsive to halogenated and polycyclic aromatic hydrocarbons.2008
- Author(s)
  Kasai A, Hiramatsu N, Hayakawa K, Yao J, and Kitamura M
- Journal Title
  
  Environ Health Perspect 116
  
  Pages: 349-354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19651024
[Journal Article] Endoplasmic reticulum stress and unfolded protein response in renal pathophysiology: Janus faces2008
- Author(s)
  Kitamura M
- Journal Title
  
  Am J Physiol - Renal
  
  Volume: 295 Issue: 2 Pages: F323-F334
- DOI
  10.1152/ajprenal.00050.2008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Involvement of hypoxia-triggered endoplasmic reticulum stress in outlet obstruction-induced apoptosis in the urinary bladder2008
- Author(s)
  Sawada N, Yao J, Hiramatsu N, Hayakawa K, Araki I, Takeda M, and Kitamura M
- Journal Title
  
  Lab Invest
  
  Volume: 88 Issue: 5 Pages: 553-563
- DOI
  10.1038/labinvest.2008.21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] 糸球体メサンギウム細胞の細胞特性2008
- Author(s)
  姚建、北村正敬、追手巌
- Journal Title
  
  日本腎臓学会誌
  
  Volume: 50 Pages: 554-560
- NAID
  10024900768
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] T cell receptor-mediated signaling induces GRP78 expression in T cells : The implications in maintaining T cell viability2008
- Author(s)
  Takano S, Ando T, Hiramatsu N, Kanayama A, Maekawa S, Ohnuma Y, Enomoto N, Ogawa H, Paton AW, Paton JC, Kitamura M, and Nakao A
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 371 Issue: 4 Pages: 762-766
- DOI
  10.1016/j.bbrc.2008.04.132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] コネクシン432007
- Author(s)
  姚建、北村正敬
- Journal Title
  
  腎と透析 63
  
  Pages: 522-525
- Data Source
  KAKENHI-PROJECT-17659255
[Journal Article] Atypical,bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response.2007
- Author(s)
  Yokouchi M, Hiramatsu N, Hayakawa K, Kasai A, Takano Y, Yao J, Kitamura M
- Journal Title
  
  Cell Death Differ 14
  
  Pages: 1467-1474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Atypical, bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response2007
- Author(s)
  Yokouchi, M., Hiramatsu, N., Hayakawa, K., Kasai, A., Takano, Y., Yao, J., Kitamura, M
- Journal Title
  
  Cell Death Differ 14
  
  Pages: 1467-1474
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Rapid, transient induction of ER stress in the liver and kidney after acute exposure to heavy metal : Evidence from transgenic sensor mice2007
- Author(s)
  Hiramatsu, N., Kasai, A., Du, S., Takeda, M., Hayakawa, K., Okamura, M., Yao, J., Kitamura, M
- Journal Title
  
  FEBS Lett 581
  
  Pages: 2055-2059
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Cigarette smoke as a trigger for the dioxin receptor-mediated signaling pathway.2007
- Author(s)
  Kitamura M, Kasai A
- Journal Title
  
  Cancer Lett (In press)
- Data Source
  KAKENHI-PROJECT-17651026
[Journal Article] タバコ煙によるダイオキシン受容体の活性化-加齢性喫煙関連疾患におけるmissing link2007
- Author(s)
  北村正敬
- Journal Title
  
  基礎老化研究 31
  
  Pages: 1-6
- NAID
  10024377551
- Data Source
  KAKENHI-PROJECT-19651024
[Journal Article] タバコの毒性とダイオキシン受容体2007
- Author(s)
  北村正敬, 河西あゆみ
- Journal Title
  
  治療 89
  
  Pages: 574-578
- NAID
  40015344950
- Data Source
  KAKENHI-PROJECT-17651026
[Journal Article] タバコの毒性とダイオキシン受容体2007
- Author(s)
  北村正敬、河西あゆみ
- Journal Title
  
  治療 89
  
  Pages: 574-578
- NAID
  40015344950
- Data Source
  KAKENHI-PROJECT-19651024
[Journal Article] Rapid, transient induction of ER stress in the liver and kidney after acute exposure to heavy metal: Evidence from transgenic sensor mice.2007
- Author(s)
  Hiramatsu N, Kasai A, Du S, Takeda M, Hayakawa K, Okamura M, Yao J, Kitamura M
- Journal Title
  
  FEBS Lett 581
  
  Pages: 2055-2059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Real-time detection and continuous monitoring of ER stress in vitro and in vivo by ES-TRAP : Evidence for systemic, transient ER stress during endotoxemia2006
- Author(s)
  Hiramatsu, N., Kasai, A., Hayakawa, K., Yao, J., Kitamura, M
- Journal Title
  
  Nucleic Acids Res 34
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Priming of glomerular mesangial cells by activated macrophages causes blunted responses to proinflammatory stimuli2006
- Author(s)
  Hayakawa, K., Meng, Y., Hiramatsu, N., Kasai, A., Yamauchi, K., Yao, J., Kitamura, M
- Journal Title
  
  J Immunol 176
  
  Pages: 2529-2537
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Continuous, non-invasive monitoring of local microscopic inflanmation using genetically engineered cell-based biosensor2005
- Author(s)
  Meng, Y., Kasai, A., Hiramatsu, N., Hayakawa, K., Yamauchi, K., Takeda, M., Kawachi, H., Shimizu, F., Yao, J., Kitamura, M
- Journal Title
  
  Lab Invest 85
  
  Pages: 1429-1439
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Real-time monitoring of mesangial cell - macrophage cross-talk using SEAP in vitro and ex vivo2005
- Author(s)
  Meng, Y., Kasai, A., Hiramatsu, N., Hayakawa, K., Takeda, M., Shimizu, F., Kawachi, H., Yao, J., Kitamura, M
- Journal Title
  
  Kidney Int 68
  
  Pages: 886-893
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Alkaline phosphatase vs. luciferase as secreted reporter molecules in vivo2005
- Author(s)
  Hiramatsu, N., Kasai, A., Meng, Y., Hayakawa, K., Yao, J., Kitamura, M
- Journal Title
  
  Anal Biochem 339
  
  Pages: 249-256
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Genetic biosensors : Application for medicine, ecomanagement, and in vivo bioimaging2004
- Author(s)
  Masanori Kitamura
- Journal Title
  
  Recent Res.Devel.Biophys.Biochem. 4
  
  Pages: 1-13
- Data Source
  KAKENHI-PROJECT-16390243
[Patent] 特許Ｐ１５１３ＹＮＵ2013
- Inventor(s)
  北村正敬、新森英之
- Industrial Property Rights Holder
  山梨大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-02-22
- Data Source
  KAKENHI-PROJECT-20390235
[Patent] 小胞体ストレス関連実験用試薬及び小胞体ストレス関連疾患治療薬2013
- Inventor(s)
  北村正敬
- Industrial Property Rights Holder
  山梨大学
- Filing Date
  2013
- Overseas
- Data Source
  KAKENHI-PROJECT-20390235
[Patent] 特許権2006
- Inventor(s)
  北村正敬
- Industrial Property Rights Holder
  山梨大学
- Filing Date
  2006-05-19
- Description
  「研究成果報告書概要(和文)」より
- Overseas
- Data Source
  KAKENHI-PROJECT-16390243
[Presentation] Activation of AMPK Protects podocytes from Adriamycin-elicited Injury2013
- Author(s)
  Gao K, Sun W, Chi Y, Kitamura M, and Yao J
- Organizer
  International Society of Nephrology (ISN) World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Blockade of Smad signaling by 3'-deoxyadenosine: A mechanism for the anti-fibrotic potential2012
- Author(s)
  Gu L, Johno H, Nakajima S,Kato H,and Kitamura M
- Organizer
  45th Annual Meeting of American Society of Nephrology
- Place of Presentation
  San Diego, USA
- Year and Date
  2012-11-02
- Data Source
  KAKENHI-PROJECT-22651020
[Presentation] Dual regulation of cadmium-induced apoptosis by mTORC1 through induction of selective unfolded protein response2012
- Author(s)
  Kato H,Nakajima S and Kitamura M
- Organizer
  45th Annual Meeting of American Society of Nephrology
- Place of Presentation
  San Diego, USA
- Year and Date
  2012-11-03
- Data Source
  KAKENHI-PROJECT-22651020
[Presentation] Connexin43 hemichannel-mediated release of ATP suppresses AMPK activation in renal tubular epithelial cells2012
- Author(s)
  Chi Y, Gao K, Kato H, Nakajima S, Kitamura M, and Yao J
- Organizer
  45^<th> Annual Meeting of American Society of Nephrology
- Place of Presentation
  San Diego
- Year and Date
  2012-11-02
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Phenotypic shift of activated glomerular cells towards redifferentiation by the unfolded protein response2012
- Author(s)
  Johno H, Nakajima S,Kato H,Yao J, and Kitamura M
- Organizer
  45th Annual Meeting of American Society of Nephrology
- Place of Presentation
  San Diego, November
- Year and Date
  2012-11-03
- Data Source
  KAKENHI-PROJECT-22651020
[Presentation] beta-catenin signaling contributes to PDGF-elicited bladder smooth muscle cell contraction through upregulation of Cx43 expression2012
- Author(s)
  Li K, Yao J, Sawada N, Miyamoto T, Kitamura M, Takeda M
- Organizer
  2012 Annual Meeting of American Urology Association
- Place of Presentation
  Atlanta
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Suppression of inflammatory cytokines-triggered NFB activation and iNOS expression in renal tubular cells by gap junction inhibitor flufenamic acid : a critical involvement of AMPK2011
- Author(s)
  Chi Y, Yan QJ, Zhu Y, Kitamura M, and Yao J
- Organizer
  44th Annual Meeting of The American Society of Nephrology
- Place of Presentation
  Pennsylvania, Philadelphia
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Aberrant, differential and bidirectional regulation of the unfolded protein response towards cell survival by 3'-deoxyadenosine2011
- Author(s)
  Kitamura M, et al
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-20390235
[Presentation] Dysfunction of gap junctions stimulates COX-2 expression in juxtaglomerular renin-secreting cells2011
- Author(s)
  Yao J, Zhu Y, and Kitamura M
- Organizer
  44th Annual Meeting of The American Society of Nephrology
- Place of Presentation
  Pennsylvania, Philadelphia
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Aberrant, differential and bidirectional regulation of the unfolded protein response towards cell survival by 3'-deoxyadenosine2011
- Author(s)
  Kitamura M, Kato H, Saito Y, Nakajima S, Takahashi S, Johno H, Gu L
- Organizer
  第34回日本第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-20390235
[Presentation] Connexin43 contributes to puromycin-elicited podocyte injury2011
- Author(s)
  Yan QJ Chi Y, Zhu Y, Kitamura M, and Yao J
- Organizer
  44th Annual Meeting of The American Society of Nephrology
- Place of Presentation
  Pennsylvania, Philadelphia
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] NF-κB/iNOS/cAMP signaling cascade mediates inflammatory cytokines-induced upregulation of connexin43 expression and function in urinary tract infection2011
- Author(s)
  Li K, Yao J, Sawada N, Nakagomi H, Miyamoto T, Kira S, Kobayashi H, Tsuchida T, Kitamura M and Takeda M
- Organizer
  The 2011 American Urological Association Annual Meeting
- Place of Presentation
  Washington, D.C.
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Connexin hemichannels mediate low calcium-elicited activation of cAMP signaling pathway and elevation of renin production in juxtaglomerular cells.2010
- Author(s)
  Huang T, Nakajima S, Kitamura M, Yao J
- Organizer
  43rd Annual Meeting of the American Society of Nephrology.
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Platelet-derived growth factor-mediated upregulation of connexin43 in bladder smooth muscle cells: A possible role in urinary bladder overactivity2010
- Author(s)
  Sawada N, Li K, Yao J, Miyamoto T, Nakagomi H, Kira S, Kobayashi H, Tsuchida T, Araki I, Kitamura M, and Takeda M
- Organizer
  Joint Annual Meeting of International Continence Society and the International Urogynecological Association
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-22651020
[Presentation] Anti-inflammatory potential of subtilase cytotoxin: Dual suppression of NF-κB via induction of C/EBPβand mTOR- mediated dephosphorylation of Akt2010
- Author(s)
  Nakajima S,Huang T, Yao J, and Kitamura M
- Organizer
  43rd Annual Meeting of American Society of Nephrology
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-22651020
[Presentation] Connexin43 hemichannels exaggerate cadmium-induced oxidative stress and cell injury in renal tubular epithelial cells.2010
- Author(s)
  Yao J Sun W, Huang T, Nakajima S, Kitamura M
- Organizer
  43rd Annual Meeting of the American Society of Nephrology.
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Upregulation of connexin43 expression and function in urinary bladder by inflammatory cytokines2010
- Author(s)
  Li K, Sawada N, Yao J, Nakagomi H, Miyamoto T, Kira S, Araki I, Kitamura M, and Takeda M
- Organizer
  Joint Annual Meeting of International Continence Society and the International Urogynecological Association
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-22651020
[Presentation] Participation of gap junction hemichannel in low calcium-elicied renin synthesis and secretion.2010
- Author(s)
  Huang T, Chi Y, Fan X, Zhu Y, Kitamura M, Yao J
- Organizer
  第53回日本腎臓学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Connexin hemichannels mediate low calcium-elicited activation of cAMP signaling pathway and elevation of renin production in juxtaglomerular cells2010
- Author(s)
  Huang T, Nakajima S, Kitamura M, Yao J
- Organizer
  43rd Annual Meeting of American Society of Nephrology
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-22651020
[Presentation] Induction of CHOP by cigarette smoke through the superoxide anion-triggered PERK - eIF2αpathway2010
- Author(s)
  Tagawa Y, Nakajima S, Kato H, and Kitamura M
- Organizer
  第33回日本分子生物学会年会/第83回日本生化学会大会合同大会 BMB2010
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22651020
[Presentation] Aryl hydrocarbon receptor経路の活性化によるデキストラン硫酸ナトリウム誘導性大腸炎の抑制2010
- Author(s)
  高村武之、原間大輔、下川直美、北村正敬、中尾篤人
- Organizer
  第47回日本消化器免疫学会総会
- Place of Presentation
  滋賀
- Data Source
  KAKENHI-PROJECT-22651020
[Presentation] Anti-inflammatory potential of subtilase cytotoxin : Dual suppression of NF-κB via induction of C/EBPβand mTOR-mediated dephosphorylation of Akt.2010
- Author(s)
  Nakajima S, Huang T, Yao J, Kitamura M
- Organizer
  43rd Annual Meeting of The American Society of Nephrology.
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-20390235
[Presentation] Connexin43 hemichannels exaggerate cadmium-induced oxidative stress and cell injury in renal tubular epithelial cells2010
- Author(s)
  Yao J, Sun W, Huang T, Nakajima S, and Kitamura M
- Organizer
  43rd Annual Meeting of The American Society of Nephrology
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-22651020
[Presentation] 喫煙による眼球表面への影響2010
- Author(s)
  樋口明弘、伊藤香織、ムラト・ドール、北村正敬、坪田一男
- Organizer
  第33回日本分子生物学会年会/第83回日本生化学会大会合同大会 BMB2010
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22651020
[Presentation] Endoplasmic reticulum stress regulates gap junction expression and function in glomerular mesangial cells.2009
- Author(s)
  Huang T, Zhu Y, Wan Y, Hiramatsu N, Paton AW, Paton JC, Kitamura M, Yao J
- Organizer
  第52回日本腎臓学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Subtilase cytotoxin suppresses TNF-α-induced activation of NF-κB via induction of C/EBPβand suppression of Akt.2009
- Author(s)
  Nakajima S, Hiramatsu N, Hayakawa K, Saito Y, Huang T, Yao J, Kitamura M
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-08
- Data Source
  KAKENHI-PROJECT-20390235
[Presentation] Gap junction renders renal tubular cells vulnerable to cadmium-induced injury.2009
- Author(s)
  Fang X, Huang T, Zhu Y, Kitamura M, Yao J
- Organizer
  第52回日本腎臓学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Suppression of NF-κB by cyclosporine A and tacroLimus (FK506) via induction of the C/EBP family : Implication for unfold protein response response.2008
- Author(s)
  Hayakawa K, Du S, Hiramatsu N, Kasai A, Okamura M, Huang T,Yao J, Sawada N, Takeda M, Kitamura M
- Organizer
  第31回日本分子生物学会年会/第82回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20390235
[Presentation] Gap junction renders renal tubular cell vulnerable to aminoglycosides-induced cytotoxicity.2008
- Author(s)
  Yao J, Huang T, Hiramatsu N, Kitamura M
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Suppression of NF-icB by cyclosporine A and tacrolimus(FK506)via inducrion of the GEB family : Implication for unfolded protein response.2008
- Author(s)
  Kitamura M, Du S, Hiramatsu N, Hayakawa K, Okamura M, Huang T, Yao J, Takeda M
- Organizer
  41st Annual Meeting of The American Society of Nephrology.
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-20390235
[Presentation] High-throughput screening of chemicals for blockade of the dioxin pathwqay in traditional Chinese medicine.2008
- Author(s)
  Kitamura M
- Organizer
  Xlth World Conference on Clinical Pharmacology and Therapeutics
- Place of Presentation
  Quebec, Canada
- Year and Date
  2008-07-31
- Data Source
  KAKENHI-PROJECT-19651024
[Presentation] Participation of gap junction in proteasome inhibition-induced cell damage.2008
- Author(s)
  Huang T, Kitamura M, Yao J
- Organizer
  第31回日本分子生物学会年会/第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Suppression of NF-B by cyclosporine A and tacrolimus (Fk506) via induction of the C/EBP family : Implication for unfolded protein response.2008
- Author(s)
  Kitamura M, et al.
- Organizer
  41st Annual Meeting of The American Society of Nephrology
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-20390235
[Presentation] Direct, continuous monitoring of air pollution by transgenic sensor mice responsive to halogenated and polycyclic aromatic hydrocarbons.2007
- Author(s)
  Kasai A, Hiramatsu N, Hayakawa K, Okamura M, Shimada T, Yao J, Kitamura M
- Organizer
  Dioxin 2007
- Place of Presentation
  東京
- Year and Date
  2007-09-02
- Data Source
  KAKENHI-PROJECT-19651024
[Presentation] Rapid,transient induction of ER stress in the liver and kidney after acute exposure to heavy metal: Evidence from transgenic sensor mice.2007
- Author(s)
  Kasai A, Hiramatsu N, Du S, Takeda M, Hayakawa K, Okamura M, Yao J, Kitamura M
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-16390243
[Presentation] Rapid, transient induction of ER stress in the liver and kidney after acute exposure to heavy metal : Evidence from transgenic sensor mice2007
- Author(s)
  Kasai, A., Hiramatsu, N., Du, S., Takeda, M., Hayakawa, K., Okamura, M., Yao, J., Kitamura, M
- Organizer
  BMB 2007
- Place of Presentation
  Yokohama, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Presentation] Real-time detection and continuous monitoring of ER stress in vitro and in vivo by ES-TRAP : Evidence for systemic, transient ER stress during endotoxemia2006
- Author(s)
  Hiramatsu, N., Kasai, A., Hayakawa, K., Yao, J., Kitamura, M
- Organizer
  39th Annual Meeting of Am Soc Nephrol
- Place of Presentation
  San Diego
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Presentation] Cadmium-induced apoptosis of renal tubular cells via endoplasmic reticulum stress : Involvement of selective unfolded protein responses2006
- Author(s)
  Yokouchi, M., Hiramatsu, N., Hayakawa, K., Kasai, A., Takano, Y., Yao, J., Kitamura, M
- Organizer
  39th Annual Meeting of Am Soc Nephrol
- Place of Presentation
  San Diego
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243

1. YAO Jian (50303128)

# of Collaborated Projects: 7 results

# of Collaborated Products: 87 results
2. TAKEDA Masayuki (80197318)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. MURAT Dogru (60385284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. HIGUCHI Akihiro (20383755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. OITE Takashi (60018744)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MORIOKA Tetsuo (00210146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 佐々木佳代子 (70338903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 田邉信明 (20163602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 荒木勇雄 (50252424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 前田秀一郎 (10117244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KITAMURA Masanori 北村 正敬

Research Projects

Research Products

Co-Researchers

小胞体ストレス応答系が有する多彩な抗炎症的役割の網羅的解明と新規治療戦略の樹立Principal Investigator

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Role of gap junction-mediated intercellular communication on schaemia/reperfusion renal injury

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Prevention of ulcerative colitis by cigarettesmoking: Development of a novel therapeutic strategy using genetically engineered micePrincipal Investigator

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Assessment of the lacrimal and ocular surface damage mechanism related to smoking

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Roles of ER stress in renal pathophysiology and development of novel therapeutic approaches to kidney diseasesPrincipal Investigator

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Role of intercellular communication in the control of renin secretion

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遺伝子組換えマウスを用いた喫煙および喫煙環境の総合的・継続的リスク評価Principal Investigator

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トランスジェニックセンサーマウスを用いた環境パトロールシステムの構築Principal Investigator

Principal Investigator

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ギャップ結合を介した細胞間コミュニケーションの炎症性賢障害における役割

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ギャップ結合を介した血管内皮細胞由来弛緩因子による傍糸球体細胞レニン分泌制御機構

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Development of in vivo biosensors using genetic engineeringPrincipal Investigator

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The mechanisms involved in the regulation of mmesangial cell phenotype by endothetial cells : role of gap junction

Principal Investigator

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幹細胞を用いた腎糸球体再生の試みPrincipal Investigator

Principal Investigator

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KITAMURA Masanori 北村正敬