KUSUNOKI Hideki 楠英樹

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楠英樹クスノキヒデキ

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Researcher Number	90334060
Other IDs
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所次世代生物学的製剤研究センター, 室長
Affiliation (based on the past Project Information) *help	2025: 国立感染症研究所, 次世代生物学的製剤研究センター, 室長 2022 – 2023: 国立感染症研究所, 次世代生物学的製剤研究センター, 室長 2011 – 2012: 国立感染症研究所, 血液・安全性研究部, 主任研究官
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Pathological medical chemistry
Keywords	Principal Investigator 多量体化 / HBx / B型肝炎ウイルス / Bcl-xL / HCV感染 / B細胞リンパ腫 / 分子腫瘍学 / HCV 感染 / B 細胞リンパ腫 / A20

HBV X蛋白質変異体の凝集化によるHBV複製と肝病変発症機構の解明と阻害剤の検討Principal Investigator
- Principal Investigator
  
  楠英樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  National Institute of Infectious Diseases
B型肝炎ウイルス複製に関わるBcl-xL多量体化機構の解明と阻害剤の検討Principal Investigator
- Principal Investigator
  
  楠英樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  National Institute of Infectious Diseases
Research on the mechanism of tumorigenesis by A20 dysfunction in HCV-infected B cellsPrincipal Investigator
- Principal Investigator
  
  KUSUNOKI Hideki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Institute of Infectious Diseases

All 2024 2022 2011

All Journal Article Presentation

[Journal Article] Structural Insights into the Interaction between the C-Terminal-Deleted BH3-like Motif Peptide of Hepatitis B Virus X Protein and Bcl-x<sub>L</sub>2024
- Author(s)
  Kusunoki Hideki、Sakamoto Taiichi、Kobayashi Naohiro、Kohno Toshiyuki、Wakamatsu Kaori、Nagata Takashi
- Journal Title
  
  Biochemistry
  
  Volume: 63 Issue: 5 Pages: 632-643
- DOI
  10.1021/acs.biochem.3c00709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06574, KAKENHI-PROJECT-23K05664, KAKENHI-PROJECT-20K06524
[Journal Article] Chemical shift assignments of a fusion protein comprising the C-terminal-deleted hepatitis B virus X protein BH3-like motif peptide and Bcl-xL2022
- Author(s)
  Kusunoki Hideki、Hamaguchi Isao、Kobayashi Naohiro、Nagata Takashi
- Journal Title
  
  Biomolecular NMR Assignments
  
  Volume: 16 Issue: 2 Pages: 357-361
- DOI
  10.1007/s12104-022-10104-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06524, KAKENHI-PROJECT-22K06574
[Journal Article] HCV infection and B-cell lymphomagenesis2011
- Author(s)
  Ito, M., Kusunoki H., Mizuochi T.
- Journal Title
  
  Adv.Hematol.
  
  Volume: 2011 Pages: 835314-835314
- DOI
  10.1155/2011/835314
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22112517, KAKENHI-PROJECT-23659177
[Journal Article] Peripheral B cells as reservoirs for persistent HCV infection2011
- Author(s)
  Ito, M., Kusunoki H., Mochida, K., Yamaguchi, K., Mizuochi T.
- Journal Title
  
  Front.Microbiol.
  
  Volume: 2 Pages: 177-177
- DOI
  10.3389/fmicb.2011.00177
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22112517, KAKENHI-PROJECT-23659177
[Journal Article] Peripheral B cells as reservoirs for persistent HCV infection.2011
- Author(s)
  M. Ito, H. Kusunoki, and T. Mizuochi
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: Volume 2 Pages: 177-177
- Data Source
  KAKENHI-PROJECT-23659177
[Journal Article] HCV infection and B-cell lymphomagenesis.2011
- Author(s)
  M. Ito, H. Kusunoki, K. Mochida, K. Yamaguchi,and T. Mizuochi
- Journal Title
  
  Advanced in Hematology
  
  Volume: Volume 2011
- Data Source
  KAKENHI-PROJECT-23659177
[Presentation] B型肝炎ウイルスX蛋白質（HBx）のC末側欠失変異体ペプチドと抗アポトーシス蛋白質Bcl-xLの相互作用のNMR解析2022
- Author(s)
  楠英樹、坂本泰一、河野俊之、若松馨、浜口功、永田崇
- Organizer
  第61回　NMR討論会
- Data Source
  KAKENHI-PROJECT-22K06574

1. MIZUOCHI Toshiaki (30135701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. OKUMA Kazu (80315085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. ITO Masahiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. NAGATA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KUSUNOKI Hideki 楠 英樹

楠 英樹 クスノキ ヒデキ

Research Projects

Research Products

Co-Researchers

HBV X蛋白質変異体の凝集化によるHBV複製と肝病変発症機構の解明と阻害剤の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

B型肝炎ウイルス複製に関わるBcl-xL多量体化機構の解明と阻害剤の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on the mechanism of tumorigenesis by A20 dysfunction in HCV-infected B cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Structural Insights into the Interaction between the C-Terminal-Deleted BH3-like Motif Peptide of Hepatitis B Virus X Protein and Bcl-x<sub>L</sub>2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemical shift assignments of a fusion protein comprising the C-terminal-deleted hepatitis B virus X protein BH3-like motif peptide and Bcl-xL2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HCV infection and B-cell lymphomagenesis2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Peripheral B cells as reservoirs for persistent HCV infection2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Peripheral B cells as reservoirs for persistent HCV infection.2011

Author(s)

Journal Title

Data Source

[Journal Article] HCV infection and B-cell lymphomagenesis.2011

Author(s)

Journal Title

Data Source

[Presentation] B型肝炎ウイルスX蛋白質（HBx）のC末側欠失変異体ペプチドと 抗アポトーシス蛋白質Bcl-xLの相互作用のNMR解析2022

Author(s)

Organizer

Data Source

KUSUNOKI Hideki 楠英樹

楠英樹クスノキヒデキ

[Presentation] B型肝炎ウイルスX蛋白質（HBx）のC末側欠失変異体ペプチドと抗アポトーシス蛋白質Bcl-xLの相互作用のNMR解析2022