Tanimoto Keiji 谷本圭司

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TANIMOTO Keiji 谷本圭司

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Researcher Number	90335688
Other IDs
External Links
Affiliation (Current)	2023: 広島大学, 原爆放射線医科学研究所, 准教授
Affiliation (based on the past Project Information) *help	2023: 広島大学, 原爆放射線医科学研究所, 准教授 2019 – 2021: 広島大学, 原爆放射線医科学研究所, 准教授 2015 – 2019: 広島大学, 原爆放射線医科学研究所, 助教 2008 – 2013: Hiroshima University, 原爆放射線医科学研究所, 助教 2002 – 2006: Department of Translational Cancer Research, Research Institute for Radiation Biology and Medicine, Hiroshima University, Research Associate, 原爆放射線医科学研究所, 助手 2001: 広島大学, 原爆放射能医学研究所, 助手
Review Section/Research Field	Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related / Biological Sciences / Pathobiological dentistry/Dental radiology Except Principal Investigator Surgical dentistry / Basic Section 55060:Emergency medicine-related / General surgery / Surgical dentistry / Digestive surgery
Keywords	Principal Investigator hypoxia / 低酸素 / 遺伝子 / 転写制御 / DEC / HIF / Hypoxia / oral cancer / hypoxia-inducible factor-1 / 発現制御 … More / 癌 / transgenic mice / hypoxia-inducible factor / がん分子標的治療 / gene expression / molecular target / siRNA / 分子標的治療 / 転写因子 / 低酸素応答 / DEC2 / DEC1 / 細胞分化 / がん細胞分化 / がん幹細胞 / がん / Cancer cell / Cancer cells / Transcription / DNA repair / トランスレーショナルリサーチ / 分子標的 / protein complex / hypoxia-response element / hypoxia response element / プロテオミクス / 口腔癌細胞 / HIF-1 / ミスマッチ修復 / 低酸素応答性転写因子 / 放射線療法 / 化学療法 / 口腔扁平上皮癌 / chemotherapy / microarray / squamous cell carcinoma / 抗癌剤 / 口腔癌 / ストレス / 応用動物 / tumor-stroma / head and neck cancer / transcription factor / genetic polymorphism / angiogenesis … More Except Principal Investigator hypoxia-inducible factor / hypoxia / head and neck cancer / oral cancer / squamous cell carcinoma / hypoxia response element / oral squamous cell carcinoma / molecular epidemiology / genetic polymorphism / transcription factor / angiogenesis / 高線量被ばく / 放射線災害 / 低酸素誘導因子 / HIF-PH阻害薬 / 放射線複合障害 / 発現制御 / 遺伝子 / 生理活性 / 食品 / 癌 / 分化誘導 / エストロゲンレセプター / エピゲノム / ヒストン修飾 / DNAメチル化 / ヒストンアセチル化 / p21 / E-カドヘリン / Bcl2阻害剤 / 細胞浸潤能 / 細胞形態 / レスベラトロール / トリプルネガティブ乳がん / 上皮間葉移行 / 転写因子Twist1 / 転写因子DEC2 / 転写因子DEC1 / Twist1 / DEC1 / 転写因子 / 口腔扁平上皮癌 / anti-angiogenesis / luciferase reporter system / transcription / molecular targeting therapy / hypoxia-inducible factor-1 / hypoxia-response element / HIF-1 / Hypoxia / hyupoxia / 癌抑制遺伝子 / 食道外科学 Less

Hypoxia Inducible Factor-Proline Hydroxylase (HIF-PH) Inhibitors as a Treatment Strategy for Combined Radiation Injury
- Principal Investigator
  
  廣橋伸之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Hiroshima University
HIF-DEC下流のクリティカル遺伝子を標的としたがん治療分子標的治療法の開発Principal Investigator
- Principal Investigator
  
  谷本圭司
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hiroshima University
Development of a molecular targeting anti-cancer therapy against hypoxia inducible DEC transcription factorsPrincipal Investigator
- Principal Investigator
  
  Tanimoto Keiji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hiroshima University
Novel therapeutic and preventive strategy of resveratrol treatment in triple negative breast cancer cells
- Principal Investigator
  
  Sakamoto Takako
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Jichi Medical University
Functions of a novel hypoxia-inducible reprogramming factor GLIS1 in cancer cellsPrincipal Investigator
- Principal Investigator
  
  Tanimoto Keiji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Molecular mechanisms of DEC-Twist transcription factors in oral squamous cell carcinoma
- Principal Investigator
  
  BHAWAL Ujjal
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
The roles of HIF-DEC pathway on DNA repair systems in hypoxic oral cancer cells.Principal Investigator
- Principal Investigator
  
  TANIMOTO Keiji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Hiroshima University
Identification of EMP3 as a tumor suppressor gene for esophageal squamous cell carcinoma and elucidation of its regulation mechanism.
- Principal Investigator
  
  NOGUCHI Tsuyoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Oita University
口腔癌細胞における新規低酸素誘導遺伝子EFEMP2機能解析Principal Investigator
- Principal Investigator
  
  TANIMOTO Keiji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
口腔癌低酸素領域における抗癌剤および放射線耐性機構の解明Principal Investigator
- Principal Investigator
  
  谷本圭司
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
プロテオミクス法によるHIF-1α複合体精製および口腔癌細胞における機能解析Principal Investigator
- Principal Investigator
  
  谷本圭司
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
活性型低酸素応答性転写因子HIF-1α遺伝子導入マウスの作製および解析Principal Investigator
- Principal Investigator
  
  谷本圭司
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
Mechanisms of inhibitory effect on hypoxia-inducible transcriptional activities.
- Principal Investigator
  
  YOSHIGA Koji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  HIROSHIMA UNIVERSITY
活性型低酸素応答性転写因子HIF-1α遺伝子導入マウスの作製および解析Principal Investigator
- Principal Investigator
  
  谷本圭司
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hiroshima University
Molecular diagnosis and therapy based on mechanisms of the regulation of hypoxia-inducible
- Principal Investigator
  
  YOSHIGA Koji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  HIROSHIMA UNIVERSITY

[Book] Simple EGFR mutation screening by conventional PCR. (In "Clinical Application of Molecular Diagnosis-Cancer, Radiation Effects, and Human Diseases-".)2010
- Author(s)
  Marina Arifin, Keiji Tanimoto, Wiwien Heru Wiyono, Keiko Hiyama.
- Publisher
  Transworld Research Network, Kerala
- Data Source
  KAKENHI-PROJECT-20592335
[Book] Individualized chemotherapy for cancer. (In "Clinical Application of Molecular Diagnosis -Cancer, Radiation Effects, and Human Diseases-".)2010
- Author(s)
  Keiji Tanimoto, Keiko Hiyama, Masahiko Nishiyama.
- Publisher
  Transworld Research Network, Kerala
- Data Source
  KAKENHI-PROJECT-20592335
[Book] 入門腫瘍内科学(I総論,3がんの発生(病因)とその特徴,5細胞死;テロメア・テロメラーゼ)2009
- Author(s)
  檜山桂子, 谷本圭司, 檜山英三
- Publisher
  篠原出版社
- Data Source
  KAKENHI-PROJECT-20592335
[Book] みんなに役立つ乳癌の基礎と臨床(I.乳癌の基礎,10.乳癌とテロメラーゼ)2009
- Author(s)
  檜山桂子, 谷本圭司, 檜山英三
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-20592335
[Book] Role of Telomeres and Telomerase in Cancer. (In "Telomeres and Telomerase in Cancer".)2009
- Author(s)
  Keiko Hiyama, Eiso Hiyama, Keiji Tanimoto, Masahiko Nishiyama.
- Publisher
  Humana press, Springer, New York
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] Biphasic Functions of Sodium Fluoride (NaF) in Soft and in Hard Periodontal Tissues2022
- Author(s)
  Wang Xingzhi、Tewari Nitesh、Sato Fuyuki、Tanimoto Keiji、Thangavelu Lakshmi、Makishima Makoto、Bhawal Ujjal K.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 2 Pages: 962-962
- DOI
  10.3390/ijms23020962
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K10073, KAKENHI-PROJECT-21K10238
[Journal Article] Low-Dose-Rate Irradiation Suppresses the Expression of Cell Cycle-Related Genes, Resulting in Modification of Sensitivity to Anti-Cancer Drugs2022
- Author(s)
  Shimabukuro K, Fukazawa T, Kanai A, Kawai H, Mekata K, Hirohashi N, Kakimoto N, Tanimoto K.
- Journal Title
  
  Cells
  
  Volume: 11(3) Issue: 3 Pages: 501-501
- DOI
  10.3390/cells11030501
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12322, KAKENHI-PROJECT-20K20310, KAKENHI-PROJECT-21K10073, KAKENHI-PROJECT-21K12239
[Journal Article] The roles of Y-box-binding protein (YB)-1 and C-X-C motif chemokine ligand 14 (CXCL14) in the progression of prostate cancer via extracellular-signal-regulated kinase (ERK) signaling2021
- Author(s)
  Wang C, Zhao N, Sato F, Tanimoto K, Okada H, Liu Y, Bhawal UK
- Journal Title
  
  Bioengineered
  
  Volume: 12 Issue: 2 Pages: 9128-9139
- DOI
  10.1080/21655979.2021.1993537
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08710, KAKENHI-PROJECT-21K10073, KAKENHI-PROJECT-21K10238
[Journal Article] Tamoxifen resistance alters sensitivity to 5-fluorouracil in a subset of estrogen receptor-positive breast cancer2021
- Author(s)
  Watanabe Takayuki、Oba Takaaki、Tanimoto Keiji、Shibata Tomohiro、Kamijo Shinobu、Ito Ken-ichi
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 6 Pages: e0252822-e0252822
- DOI
  10.1371/journal.pone.0252822
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20J00393, KAKENHI-PROJECT-21K06641, KAKENHI-PROJECT-21K10073, KAKENHI-PROJECT-21KK0276
[Journal Article] The Potential Roles of Dec1 and Dec2 in Periodontal Inflammation2021
- Author(s)
  Wang X, Sato F, Tanimoto K, Rajeshwaran N, Thangavelu L, Makishima M, Bhawal UK
- Journal Title
  
  Int J Mol Sci
  
  Volume: 22 Issue: 19 Pages: 10349-10349
- DOI
  10.3390/ijms221910349
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08710, KAKENHI-PROJECT-21K10073, KAKENHI-PROJECT-21K10238
[Journal Article] Inhibiting SARS-CoV-2 infection in vitro by suppressing its receptor, angiotensin-converting enzyme 2, via aryl-hydrocarbon receptor signal2021
- Author(s)
  Tanimoto Keiji、Hirota Kiichi、Fukazawa Takahiro、Matsuo Yoshiyuki、Nomura Toshihito、Tanuza Nazmul、Hirohashi Nobuyuki、Bono Hidemasa、Sakaguchi Takemasa
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 16629-16629
- DOI
  10.1038/s41598-021-96109-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09339, KAKENHI-PROJECT-20H03776, KAKENHI-PROJECT-20K09210, KAKENHI-PROJECT-21K10073
[Journal Article] GLIS1, a novel hypoxia-inducible transcription factor, promotes breast cancer cell motility via activation of WNT5A.2020
- Author(s)
  Kazumi Shimamoto, Keiji Tanimoto*, Takahiro Fukazawa, Hideaki Nakamura, Akinori Kanai, Hidemasa Bono, Hiromasa Ono, Hidetaka Eguchi, Nobuyuki Hirohashi
- Journal Title
  
  Carcinogenesis
  
  Volume: inpress Issue: 9 Pages: 1184-1194
- DOI
  10.1093/carcin/bgaa010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09768, KAKENHI-PROJECT-17K10561, KAKENHI-PROJECT-18K18196
[Journal Article] がんにおける低酸素応答性転写因子HIF2020
- Author(s)
  谷本圭司
- Journal Title
  
  医学のあゆみ
  
  Volume: 274 Pages: 265-270
- Data Source
  KAKENHI-PROJECT-18K09768
[Journal Article] Simulated microgravity enhances CDDP-induced apoptosis signal via p53-independent mechanisms in cancer cells.2019
- Author(s)
  Takahiro Fukazawa, Keiji Tanimoto*, Looniva Shrestha, Takeshi Imura, Shinya Takahashi, Taijiro Sueda, Nobuyuki Hirohashi, Eiso Hiyama, Louis Yuge
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 7 Pages: 1-14
- DOI
  10.1371/journal.pone.0219363
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09768, KAKENHI-PROJECT-17K10561, KAKENHI-PROJECT-17K10758, KAKENHI-PROJECT-19H01056, KAKENHI-PROJECT-16H02778
[Journal Article] Simulated microgravity attenuates myogenic differentiation via epigenetic regulations2018
- Author(s)
  Takuma Furukawa, Keiji Tanimoto, Takahiro Fukazawa, Takeshi Imura, Yumi Kawahara, Louis Yuge
- Journal Title
  
  Npj Microgravity
  
  Volume: 4 Issue: 1
- DOI
  10.1038/s41526-018-0045-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09768
[Journal Article] Differentiated embryo chondrocyte plays a crucial role in DNA damage response via transcriptional regulation under hypoxic conditions2018
- Author(s)
  Nakamura Hideaki、Bono Hidemasa、Hiyama Keiko、Kawamoto Takeshi、Kato Yukio、Nakanishi Takeshi、Nishiyama Masahiko、Hiyama Eiso、Hirohashi Nobuyuki、Sueoka Eisaburo、Poellinger Lorenz、Tanimoto Keiji
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 2 Pages: e0192136-e0192136
- DOI
  10.1371/journal.pone.0192136
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02567, KAKENHI-PROJECT-15K08553, KAKENHI-PROJECT-15K11252, KAKENHI-PROJECT-16K09850, KAKENHI-PROJECT-16H02778
[Journal Article] A chemical modulator of p53 transactivation that acts as a radioprotective agonist.2018
- Author(s)
  Akinori Morita, Ippei Takahashi, Megumi Sasatani, Shin Aoki, Bing Wang, Shinya Ariyasu, Kaoru Tanaka, Tetsuji Yamaguchi, Akiko Sawa, Yurie Nishi, Tatsuro Teraoka, Shohei Ujita, Yosuke Kawate, Chihiro Yanagawa, Keiji Tanimoto, Atsushi Enomoto, Mitsuru Nenoi, Kenji Kamiya, Yasushi Nagata, Yoshio Hosoi and Toshiya Inaba
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 17 Issue: 2 Pages: 432-442
- DOI
  10.1158/1535-7163.mct-16-0554
- NAID
  120006552353
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10396, KAKENHI-PROJECT-17K00553, KAKENHI-PROJECT-17K08225, KAKENHI-PROJECT-17K10434, KAKENHI-PROJECT-26293271, KAKENHI-PROJECT-15K11252, KAKENHI-PROJECT-20K20310
[Journal Article] Genetics of the hypoxia-inducible factors in human cancers2017
- Author(s)
  Keiji Tanimoto
- Journal Title
  
  Experimental Cell Research
  
  Volume: in press Issue: 2 Pages: 166-172
- DOI
  10.1016/j.yexcr.2017.03.035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11252
[Journal Article] The A allele at rs13419896 of EPAS1 is associated with enhanced expression and poor prognosis for non-small cell lung cancer.2015
- Author(s)
  Andika C. Putra, Hidetaka Eguchi, Kian Leong Lee, Yuko Yamane, Ewita Gustine, Takeshi Isobe, Masahiko Nishiyama, Keiko Hiyama, Lorenz Poellinger, Keiji Tanimoto*.
- Journal Title
  
  PLOS ONE
  
  Volume: 10 Issue: 8 Pages: 0134496-0134496
- DOI
  10.1371/journal.pone.0134496
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11252, KAKENHI-PROJECT-25461159, KAKENHI-PROJECT-221S0001
[Journal Article] OASIS modulates hypoxia pathway activity to regulate bone angiogenesis.2015
- Author(s)
  Min Cui, Soshi Kanemoto, Xiang Cui, Masayuki Kaneko, Rie Asada, Koji Matsuhisa, Keiji Tanimoto, Yuki Yoshimoto, Chisa Shukunami, Kazunori Imaizumi.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 16455-16455
- DOI
  10.1038/srep16455
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11252, KAKENHI-PROJECT-15K19516, KAKENHI-PROJECT-15K20001, KAKENHI-PROJECT-25251014, KAKENHI-PROJECT-13J00677, KAKENHI-PROJECT-26293395, KAKENHI-PROJECT-15K21706
[Journal Article] The transcribed-ultra conserved regions in prostate and gastric cancer: DNA hypermethylation and microRNA-associated regulation.2015
- Author(s)
  Keisuke Goto, Sho Ishikawa,Ririno Honma, Keiji Tanimoto, Naoya Sakamoto,Kazuhiro Sentani, Naohide Oue, Jun Teishima, Akio Matsubara and Wataru Yasui.
- Journal Title
  
  Oncogene
  
  Volume: 1 Issue: 27 Pages: 1-1
- DOI
  10.1038/onc.2015.445
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11252, KAKENHI-PROJECT-15H04713, KAKENHI-PROJECT-25460416, KAKENHI-PROJECT-25460417, KAKENHI-PROJECT-26670175, KAKENHI-PROJECT-16H06999, KAKENHI-PROJECT-16K08691, KAKENHI-PROJECT-16K15247
[Journal Article] Mitochondria are required for ATM activation by extranuclear oxidative stress in cultured human hepatoblastoma cell line Hep G2 cells.2014
- Author(s)
  Akinori Morita, Keiji Tanimoto, Tomoki Murakami, Takeshi Morinaga, Yoshio Hosoi.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 443 Issue: 4 Pages: 1286-1290
- DOI
  10.1016/j.bbrc.2013.12.139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766, KAKENHI-PROJECT-23659588
[Journal Article] Genetic variations in detoxification enzymes and HIF-1αin Japanese patients with COPD2013
- Author(s)
  Andika C. Putra, Keiji Tanimoto, Marina Arifin, Budhi Antariksa, Keiko Hiyama
- Journal Title
  
  Clinical Respiratory Journal 2013
  
  Volume: 7 Pages: 7-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] Development of lymphoproliferative diseases by hypoxia-inducible factor-1α is associated with prolonged lymphocyte survival2013
- Author(s)
  Eisaburo Sueoka, Naoko Sueoka-Aragane, Keiji Tanimoto. et al.
- Journal Title
  
  PLOS ONE
  
  Volume: inpress
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] Electrical stimulation accelerates neuromuscular junction formation through ADAM19/neuregulin/ErbB signaling in vitro2013
- Author(s)
  Takahiro Fukazawa, Masaya Matsumoto, Takeshi Imura, Elham Khalesi, Teruyuki Kajiume, Yumi Kawahara, Keiji Tanimoto, Louis Yuge
- Journal Title
  
  Neuroscience Letters
  
  Volume: 545 Pages: 29-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] An association study between Hypoxia inducible Factor-1alpha (HIF-1α) polymorphisms and osteonecrosis2013
- Author(s)
  Georgia Chachami, Alkmini KalousI, Loukia Papatheodorou, Aggeliki Lyberopoulou, Vassilis Nasikas, Keiji Tanimoto, G. Simos, K. N. Malizos, E. Georgatsou
- Journal Title
  
  PLOS ONE
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] An association study between Hypoxia inducible Factor-1alpha (HIF-1α) polymorphisms and osteonecrosis.2013
- Author(s)
  Georgia Chachami, Alkmini KalousI, Loukia Papatheodorou, Aggeliki Lyberopoulou, Vassilis Nasikas, Keiji Tanimoto, G. Simos, K. N. Malizos, E. Georgatsou.
- Journal Title
  
  PLOS ONE
  
  Volume: 8 Issue: 11 Pages: e79647-e79647
- DOI
  10.1371/journal.pone.0079647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] Interactive effects of cell therapy and rehabilitation realize the full potential of neurogenesis in brain injury model2013
- Author(s)
  Takeshi Imura, Masaya Matsumoto, Takahiro Fukazawa, Elham Khalesi, Ya-Nan Sun, Masaaki Takeda, Hiroyuki Uwatoko, Kyosuke Nakata, Keiji Tanimoto, Teruyuki Kajiume, Yumi Kawahara, Louis Yuge
- Journal Title
  
  Neuroscience Letters
  
  Volume: 555 Pages: 73-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] The Krüppel-like zinc finger transcription factor, GLI-similar 1, is regulated by hypoxia-inducible factors via non-canonical mechanisms2013
- Author(s)
  Elham Khalesi, Hideaki Nakamura, Kian Leong Lee, Andika Chandra Putra, Takahiro Fukazawa, Yumi Kawahara, Yuichi Makino, Lorenz Poellinger, Louis Yuge, Keiji Tanimoto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 441 Pages: 499-506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] The Krüppel-like zinc finger transcription factor, GLI-similar 1, is regulated by hypoxia-inducible factors via non-canonical mechanisms.2013
- Author(s)
  Khalesi E, Nakamura H, Leong Lee K, Chandra Putra A, Fukazawa T, Kawahara Y, Makino Y, Poellinger L, Yuge L, Tanimoto K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 441 Issue: 2 Pages: 499-506
- DOI
  10.1016/j.bbrc.2013.10.083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591453, KAKENHI-PROJECT-23592766
[Journal Article] Electrical stimulation accelerates neuromuscular junction formation through ADAM19/neuregulin/ErbB signaling in vitro2013
- Author(s)
  Takahiro Fukazawa, Keiji Tanimoto, Louis Yuge, et al.
- Journal Title
  
  Neuroscience Letters
  
  Volume: inpress
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] Development of lymphoproliferative diseases by hypoxia-inducible factor-1αis associated with prolonged lymphocyte survival2013
- Author(s)
  Eisaburo Sueoka, Naoko Sueoka-Aragane, Akemi Sato, Masaru Ide, Hideaki Nakamura, Yusuke Sotomaru, Choji Taya, Hiromichi Yonekawa, Tomoyuki Kitagawa, Yasushi Kubota, Shinya Kimura, Kei Nakachi, Keiji Tanimoto
- Journal Title
  
  PLOS ONE
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] Interactive effects of cell therapy and rehabilitation realize the full potential of neurogenesis in brain injury model2013
- Author(s)
  Imura T., Matsumoto M., Fukazawa T., Khalesi E., Sun Y.N., Takeda M., Uwatoko H., Nakata K., Tanimoto K., Kajiume T., Kawahara Y., Yuge L
- Journal Title
  
  Neurosci Lett
  
  Volume: 555 Pages: 73-78
- DOI
  10.1016/j.neulet.2013.09.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300201, KAKENHI-PROJECT-23592127, KAKENHI-PROJECT-23592766, KAKENHI-PROJECT-15K11252
[Journal Article] Yoshio Hosoi. Mitochondria are required for ATM activation by extranuclear oxidative stress in cultured human hepatoblastoma cell line Hep G2 cells2013
- Author(s)
  Akinori Morita, Keiji Tanimoto, Tomoki Murakami, Takeshi Morinaga, Yoshio Hosoi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 443 Pages: 1286-1290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] A Step forward into respiratory genetics : Overview contribution of genetics in respiratory diseases2012
- Author(s)
  Andika C. Putra, Keiji Tanimoto, Elisna Syahruddin, Sita Andarini, Yoshio Hosoi, Keiko Hiyama
- Journal Title
  
  Asian Biomedicine
  
  Volume: 5 Pages: 639-651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] A Step forward into respiratory genetics: Overview contribution of genetics in respiratory diseases2012
- Author(s)
  Andika C. Putra, Keiji Tanimoto, Elisna Syahruddin, et al.
- Journal Title
  
  Asian Biomedicine
  
  Volume: 5 Pages: 639-651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] TMEM158 and FBLP1 as Novel Marker Genes of Cisplatin Sensitivity in Non-small Cell Lung Cancer Cells2012
- Author(s)
  Ahmed El Sayed Mohammed, Hidetaka Eguchi, Satoru Wada, Nobuyuki Koyama, Michio Shimizu, Keiko Otani, Megu Ohtaki, Keiji Tanimoto, Keiko Hiyama, Mohammed Soliman Gaber, Masahiko Nishiyama
- Journal Title
  
  Experimental Lung Research
  
  Volume: 38 Pages: 463-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] IL-1β-mediated up-regulation of DEC1 in human gingiva cells via the Akt pathway2012
- Author(s)
  Ujjal K. Bhawal, Yumi Ito, Keiji Tanimoto, Fuyuki Sato, Katsumi Fujimoto, Takeshi Kawamoto, Tomonori Sasahira, Nobushiro Hamada, Hiroki Kuniyasu, Hirohisa Arakawa, Yukio Kato, Yoshimitsu Abiko
- Journal Title
  
  Journal of Cellular Biochemistry
  
  Volume: 113 Pages: 3246-3253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] Genetic variations in detoxification enzymes and HIF-1α in Japanese patients with COPD.2011
- Author(s)
  Andika C.Putra, Keiji Tanimoto, Marina Arifin, Budhi Antariksa, Keiko Hiyama
- Journal Title
  
  Clinical Respiratory Journal in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] Basic helix-loop-helix transcription factor DEC1 negatively regulates CyclinD12011
- Author(s)
  Ujjal K. Bhawal, Fuyuki Sato, Yuki Arakawa, Katsumi Fujimoto, Takeshi Kawamoto, Keiji Tanimoto, Yumi Ito, Tomonori Sasahira, Takashi Sakurai, Masaru Kobayashi, Isamu Kashima, Hiroshi Kijima, Hiroki Kuniyasu, Yoshimitsu Abiko, Yukio Kato, Sadao Sato
- Journal Title
  
  Journal of Pathology
  
  Volume: 224 Pages: 420-429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] Genetic variations in detoxification enzymes and HIF-1α in Japanese patients with COPD.2011
- Author(s)
  Andika C. Putra, Keiji Tanimoto, Marina Arifin, Budhi Antariksa, Keiko Hiyama.
- Journal Title
  
  Clinical Respiratory Journal
  
  Volume: on line
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] HIF-1αpolymorphisms associate with genetic aberrations in lung cancer2011
- Author(s)
  Andika C. Putra, Keiji Tanimoto, Marina Arifin, Keiko Hiyama
- Journal Title
  
  Respirology
  
  Volume: 16 Pages: 796-802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] HIF-1α polymorphisms associate with genetic aberrations in lung cancer.2011
- Author(s)
  Andika C. Putra, Keiji Tanimoto, Marina Arifin, Keiko Hiyama.
- Journal Title
  
  Respirology
  
  Volume: 16 Pages: 796-802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] Basic helix-loop-helix transcription factor DEC1 negatively regulates CyclinD1.2011
- Author(s)
  Ujjal K.Bhawal, Fuyuki Sato, Yuki Arakawa, Katsumi Fujimoto, Takeshi Kawamoto, Keiji Tanimoto, Yumi Ito, Tomonori Sasahira, Takashi Sakurai, Masaru Kobayashi, Isamu Kashima, Hiroshi Kijima, Hiroki Kuniyasu, Yoshimitsu Abiko, Yukio Kato, Sadao Sato.
- Journal Title
  
  Journal of Pathology in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] Basic helix-loop-helix transcription factor DEC1 negatively regulates CyclinD1.2011
- Author(s)
  Ujjal K. Bhawal, Keiji Tanimoto, et al.
- Journal Title
  
  Journal of Pathology
  
  Volume: 224 Pages: 420-429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592766
[Journal Article] HIF-1a polymorphisms associate with genetic aberrations in lung cancer.2011
- Author(s)
  Andika C.Putra, Keiji Tanimoto, Marina Arifin, Keiko Hiyama
- Journal Title
  
  Respirology in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] Carcinogenesis and cellular immortalization without persistent inactivation of p16/Rb pathway in lung cancer.2010
- Author(s)
  Marina Arifin, Keiji Tanimoto, Andika Chandra Putra, Eiso Hiyama, Masahiko Nishiyama, Keiko Hiyama
- Journal Title
  
  International Journal of Oncology 36
  
  Pages: 1217-1227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article]2010
- Author(s)
  Tanimoto K
- Journal Title
  
  Individualized chemotherapy for cancer. In : Clinical application of molecular diagnosis-cancer, radiation effects, and human diseases-. Hiyama E, Hiyama K (eds)(Transworld Research Network)
  
  Pages: 65-78
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] Individualized chemotherapy for cancer. In "Clinical Application of Molecular Diagnosis -Cancer, Radiation Effects, and Human Diseases-".2010
- Author(s)
  Keiji Tanimoto, Keiko Hiyama, Masahiko Nishiyama.
- Journal Title
  
  Transworld Research Network, Kerala 3
  
  Pages: 65-78
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] Simple EGFR mutation screening by conventional PCR. In "Clinical Application of Molecular Diagnosis -Cancer, Radiation Effects, and Human Diseases-".2010
- Author(s)
  Marina Arifin, Keiji Tanimoto, Wiwien Heru Wiyono, Keiko Hiyama
- Journal Title
  
  Transworld Research Network, Kerala 3
  
  Pages: 195-203
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] Activation of the hypoxia-inducible factor-1 in overloaded temporomandibular joint, and induction of osteoclastogenesis.2010
- Author(s)
  Maya Shirakura, Keiji Tanimoto, Hideaki Eguchi, Mutsumi Miyauchi, Hideaki Nakamura, Keiko Hiyama, Kotaro Tanimoto, Eiji Tanaka, Takashi Takata, Kazuo Tanne.
- Journal Title
  
  Biochemical and Biophysical Research Communications 393
  
  Pages: 800-805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] 入門腫瘍内科学,I総論,3がんの発生(病因)とその特徴,5細胞死2009
- Author(s)
  檜山桂子, 谷本圭司, 檜山英三
- Journal Title
  
  テロメア・テロメラーゼ(篠原出版社)
  
  Pages: 44-46
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] Role of Telomeres and Telomerase in Cancer. In "Telomeres and Telomerase in Cancer".2009
- Author(s)
  Keiko Hiyama, Eiso Hiyama, Keiji Tanimoto, Masahiko Nishiyama.
- Journal Title
  
  Humana press, Springer, New York
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] EMP3 as a tumor suppressor gene for esophageal squamous cell carcinoma2009
- Author(s)
  Shoichi Fumoto, Keiko Hiyama, Keiji Tanimoto, Takuya Noguchi, Jun Hihara, Eiso Hiyama, Tsuyoshi Noguchi, Masahiko Nishiyama
- Journal Title
  
  Cancer letters
  
  Volume: 274 Pages: 25-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591706
[Journal Article] EMP3 as a candidate tumor suppressor gene for solid tumors2009
- Author(s)
  Shoichi Fumoto, Keiji Tanimoto, Eiso Hiyama, Tsuyoshi Noguchi, Masahiko Nishiyama, Keiko Hiyama
- Journal Title
  
  Expert Opinion on Therapeutic Targets
  
  Volume: 13(7) Pages: 811-822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591706
[Journal Article] EMP3 as a candidate tumor suppressor gene for solid tumors.2009
- Author(s)
  Shoichi Fumoto, Keiji Tanimoto, Eiso Hiyama, Tsuyoshi Noguchi, Masahiko Nishiyama, Keiko Hiyama
- Journal Title
  
  Expert Opinion on Therapeutic Targets 13
  
  Pages: 811-822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] EMP3 as a tumor suppressor gene for esophageal squamous cell carcinoma.2009
- Author(s)
  Shoichi Fumoto, Keiko Hiyama, Keiji Tanimoto, Takuya Noguchi, Jun Hihara, Eiso Hiyama, Tsuyoshi Noguchi, Masahiko Nishiyama.
- Journal Title
  
  Cancer Letter 274
  
  Pages: 25-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] みんなに役立つ乳癌の基礎と臨床,I.乳癌の基礎,102009
- Author(s)
  檜山桂子, 谷本圭司, 檜山英三
- Journal Title
  
  乳癌とテロメラーゼ(医薬ジャーナル社,東京)
  
  Pages: 101-111
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] がんと低酸素2008
- Author(s)
  谷本圭司
- Journal Title
  
  がんと低酸素 225(13)
  
  Pages: 1315-1318
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] 固形癌の治療抵抗性に関わる低酸素応答分子機構2008
- Author(s)
  谷本圭司, 檜山桂子, 西山正彦
- Journal Title
  
  癌の臨床 54(2)
  
  Pages: 91-96
- NAID
  40015940990
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] 肺癌とテロメア・テロメラーゼ,肺癌-基礎・臨床研究のアップデート-,疫学・基礎研究II.,分子生物学2008
- Author(s)
  檜山桂子, 谷本圭司, 檜山英三
- Journal Title
  
  日本臨床 66(6)
  
  Pages: 59-64
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] 肺癌の分子生物学(1)-carcinogenesisとはなにか-.特集「肺癌のUp-To-Date」2008
- Author(s)
  檜山桂子, Marina Arifin, 谷本圭司
- Journal Title
  
  THE LUNG perspectives 16(4)
  
  Pages: 503-507
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] Selection of a novel drug-response predictor in esophageal cancer : A novel screening method using microarray and identification of IFITM1 as a potent marker gene of CDDP response.2008
- Author(s)
  Shoichi Fumoto, Tatsushi Shimokuni, Keiji Tanimoto, Keiko Hiyama, Keiko Otani, Megu Ohtaki, Jun Hihara, Kazuhiro Yoshida, Eiso Hiyama, Tsuyoshi Noguchi, Masahiko Nishiyama.
- Journal Title
  
  International Journal of Oncology 32
  
  Pages: 413-423
- NAID
  120006340785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] Exploration of the genes responsible for unlimited proliferation of immortalized lung fibroblasts.2008
- Author(s)
  Keiko Hiyama, Keiji Tanimoto, Yohei Nishimura, Momomi Tsugane, Ikuko Fukuba, Yusuke Sotomaru, Eiso Hiyama, Masahiko Nishiyama.
- Journal Title
  
  Experimental Lung Research 34
  
  Pages: 373-390
- NAID
  120001092454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] 分子標的治療法開発にむけた低酸素研究.2008
- Author(s)
  谷本圭司
- Journal Title
  
  日本癌病態治療研究会誌 14(1)
  
  Pages: 33-34
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] 日本における遺伝子診療・研究の現状2008
- Author(s)
  檜山桂子, 谷本圭司, 檜山英三
- Journal Title
  
  腫瘍内科 2(5
  
  Pages: 433-439
- NAID
  40016324347
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2.2008
- Author(s)
  Hideaki Nakamura, Keiji Tanimoto, Mayu Yunokawa, Takeshi Kawamoto, Yukio Kato, Koji Yoshiga, Eiso Hiyama, Lorenz Poellinger, Keiko Hiyama, Masahiko Nishiyama.
- Journal Title
  
  Oncogene 27
  
  Pages: 4200-4209
- NAID
  120001092453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] 分子標的治療法開発にむけた低酸素研究2008
- Author(s)
  谷本圭司
- Journal Title
  
  日本癌病態治療研究会誌 14(1)
  
  Pages: 33-34
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] 癌と低酸素.2008
- Author(s)
  谷本圭司
- Journal Title
  
  医学のあゆみ 225(13)
  
  Pages: 1315-1318
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] 固形癌の治療抵抗性に関わる低酸素応答分子機構2008
- Author(s)
  谷本圭司, 中村秀明, 檜山桂子, 江口英孝, 西山正彦
- Journal Title
  
  放射線生物研究 43(1)
  
  Pages: 54-67
- NAID
  40015940990
- Data Source
  KAKENHI-PROJECT-20592335
[Journal Article] Human Carboxylesterase 1A2 Expressed from Carboxylesterase 1A1 and 1A2 Genes is a Potent Predictor of CPT-11 Cytotoxicity in vitro.2007
- Author(s)
  Tanimoto K.
- Journal Title
  
  Pharmacogenetics and genomics 17
  
  Pages: 1-10
- Data Source
  KAKENHI-PROJECT-16659552
[Journal Article] Human Carboxylesterase 1A2 Expressed from Carboxylesterase 1A1 and IA2 Genes is a Potent Predictor of CPT-11 Cytotoxicity in vitro.2007
- Author(s)
  Tanimoto K.
- Journal Title
  
  Pharmacogenetics and genomics 17
  
  Pages: 1-10
- Data Source
  KAKENHI-PROJECT-16689032
[Journal Article] Towards Molecular Medicine : Cancer Pharmacogenomics, Personalized Medicine, and Our Recent Approaches.2003
- Author(s)
  Tanimoto K. et al.
- Journal Title
  
  Annals of Cancer Research and Therapy 11
  
  Pages: 61-72
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592114
[Journal Article] Hypoxia-inducible factor-1α Polymorphisms associated with enhanced transcription capacity, implying clinical significance.2003
- Author(s)
  Tanimoto K. et al.
- Journal Title
  
  Carcinogenesis 24
  
  Pages: 1779-1783
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592114
[Journal Article] Towards Molecular Medicine : Cancer Pharmnacogenomics, Personalized Medicine, and Our Recent Approaches.2003
- Author(s)
  Tanimoto K. et al.
- Journal Title
  
  Ann.Cancer Res.Therapy 11
  
  Pages: 61-72
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592114
[Presentation] The effects of low-dose irradiation on the hypoxic cells2020
- Author(s)
  Kiichi Shimabukuro, Keiji Tanimoto, Naoya Kakimoto, Nobuyuki Hirohashi
- Organizer
  The 4th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09768
[Presentation] The effects of low-dose irradiation on the hypoxic cells.2020
- Author(s)
  Kiichi Shimabukuro, Keiji Tanimoto, Naoya Kakimoto, Nobuyuki Hirohashi
- Organizer
  The 4th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science
- Data Source
  KAKENHI-PROJECT-18K09768
[Presentation] 低線量率放射線および低酸素刺激により変動する遺伝子群2020
- Author(s)
  島袋紀一，谷本圭司，柿本直也，廣橋伸之
- Organizer
  第45回中国放射線影響研究会
- Data Source
  KAKENHI-PROJECT-18K09768
[Presentation] 新規低酸素誘導性転写因子GLIS1の機能解析．2019
- Author(s)
  島本和美，谷本圭司，深澤賢宏，島袋紀一，廣橋伸之
- Organizer
  第44回中国放射線影響研究会
- Data Source
  KAKENHI-PROJECT-18K09768
[Presentation] Significant roles of the novel hypoxia-inducible transcription factor, GLIS1, in breast cancer2019
- Author(s)
  Keiji Tanimoto, Kazumi Shimamoto, Nobuyuki Hirohashi
- Organizer
  The 3rd International Symposium of the Network-type Joint Usage/Research Center for Radio Disaster Medical Science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09768
[Presentation] 食品成分レスベラトロールによるトリプルネガティブ乳がん細胞に対するBcl-2阻害剤の抗腫瘍効果の増強2019
- Author(s)
  坂本隆子、谷本圭司、江口英孝、佐々木駿太、坪井洸樹、林慎一、市原佐保子
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K10561
[Presentation] 低酸素がん細胞におけるビスフォスフォネート製剤の抗腫瘍分子機構．2019
- Author(s)
  光野　萌，谷本圭司，島袋紀一，島本和美，廣橋伸之
- Organizer
  第60回原子爆弾後障害癌研究会
- Data Source
  KAKENHI-PROJECT-18K09768
[Presentation] 低酸素シグナルと放射線応答2018
- Author(s)
  谷本圭司，島本和美，小田千代，廣橋伸之
- Organizer
  第59回原子爆弾後障害研究会
- Data Source
  KAKENHI-PROJECT-18K09768
[Presentation] DEC plays a crucial role in DNA damage response via transcriptional regulation under hypoxic conditions2018
- Author(s)
  Keiji Tanimoto, Hideaki Nakamura, Nobuyuki Hirohashi, Lorenz Poellinger, Eisaburo Sueoka
- Organizer
  The 14th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09768
[Presentation] 新規低酸素誘導性転写因子GLIS1のがん細胞における意義2018
- Author(s)
  谷本圭司，島本和美，島袋紀一，小田千代，廣橋伸之
- Organizer
  第61回日本放射線影響学会
- Data Source
  KAKENHI-PROJECT-18K09768
[Presentation] がん細胞における低酸素応答機構の解明2012
- Author(s)
  谷本圭司
- Organizer
  島根大学医学部がんプロフェッショナル養成プランセミナー
- Place of Presentation
  出雲
- Year and Date
  2012-03-22
- Data Source
  KAKENHI-PROJECT-23592766
[Presentation] 低酸素研究の10年−低酸素応答のゲノム研究−2012
- Author(s)
  谷本圭司
- Organizer
  第10回がんとハイポキシア研究会特別企画シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2012-12-06
- Data Source
  KAKENHI-PROJECT-23592766
[Presentation] 低酸素応答のゲノム解析研究2012
- Author(s)
  谷本圭司
- Organizer
  第10回　がんとハイポキシア研究会
- Place of Presentation
  横浜開港記念会館
- Invited
- Data Source
  KAKENHI-PROJECT-23592766
[Presentation] がん細胞におけるVHL蛋白制御機構2011
- Author(s)
  谷本圭司, 他
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  北海道大学
- Year and Date
  2011-01-30
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] がん細胞における低酸素応答機構の解明2011
- Author(s)
  谷本圭司
- Organizer
  佐賀大学医学部セミナー
- Place of Presentation
  佐賀
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-23592766
[Presentation] がん細胞におけるVHL蛋白制御機構2011
- Author(s)
  谷本圭司, 江口英孝, 和田智, 西山正彦, 檜山英三, 中村秀明, Lorenz Poellinger, 檜山桂子
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  札幌
- Year and Date
  2011-01-30
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] がん細胞におけるVHL蛋白制御機構2011
- Author(s)
  谷本圭司,江口英孝,和田智,西山正彦,檜山英三,中村秀明,Lorenz Poellinger,檜山桂子
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  札幌
- Year and Date
  2011-01-30
- Data Source
  KAKENHI-PROJECT-23592766
[Presentation] DNA修復関連遺伝子の低酸素応答性転写抑制機構2011
- Author(s)
  谷本圭司,中村秀明,河本健,加藤幸夫,檜山英三,檜山桂子,西山正彦,森田明典,細井義夫
- Organizer
  第54回放射線影響学会ワークショップ低酸素バイオロジー研究に基づく放射線生物学・放射線腫瘍学の新展開
- Place of Presentation
  神戸
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-23592766
[Presentation] がん細胞におけるVHL蛋白制御機構2011
- Author(s)
  谷本圭司, 他
- Organizer
  第8回がんとハイポキシア研究会
- Place of Presentation
  北海道大学
- Year and Date
  2011-01-30
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Activation of the hypoxia-inducible factor-1 in chondrocytes2010
- Author(s)
  谷本圭司
- Organizer
  Keystone Symposia, Hypoxia : Molecular Mechanisms of Oxygen Sensing and Response Pathway
- Place of Presentation
  Keystone
- Year and Date
  2010-01-22
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] Activation of the hypoxia-inducible factor-1 in chondrocytes. Keystone Symposia, Hypoxia2010
- Author(s)
  Keiji Tanimoto, Maya Shirakura, Hideaki Nakamura, Eiso Hiyama, Keiko Hiyama.
- Organizer
  Molecular Mechanisms of Oxygen Sensing and Response Pathway, Keystone, Colorado
- Place of Presentation
  USA
- Year and Date
  2010-01-22
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Alteration of the DNA repair system in hypoxic cancer cells2010
- Author(s)
  谷本圭司, 他
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] 低酸素下がん細胞におけるDNA損傷応答抑制機構2010
- Author(s)
  谷本圭司, 他
- Organizer
  第53回放射線影響学会
- Place of Presentation
  京都テルサ
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] Activation of the hypoxia-inducible factor-1 in chondrocytes2010
- Author(s)
  Keiji Tanimoto
- Organizer
  Molecular Mechanisms of Oxygen Sensing and Response Pathway
- Place of Presentation
  Keystone, Colorado
- Year and Date
  2010-01-22
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] Molecular mechanisms of regulation of the pVHL by oncogenic UBE2S/E2-EPF.2010
- Author(s)
  Keiji Tanimoto, Hidetaka Eguchi, Satoru Wada, Shoichi Fumoto, Hideaki Nakamura, Lorenz Poellinger, Eiso Hiyama, Masahiko Nishiyama, Keiko Hiyama.
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Alteration of the DNA repair system in hypoxic cancer cells2010
- Author(s)
  谷本圭司, 他
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Activation of the hypoxia-inducible factor-1 in chondrocytes2010
- Author(s)
  谷本圭司
- Organizer
  Keystone Symposia, Hypoxia : Molecular Mechanisms of Oxygen Sensing and Response Pathway
- Place of Presentation
  Keystone, USA
- Year and Date
  2010-01-22
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Molecular mechanisms of regulation of the pVHL by oncogenic UBE2S/E2-EPF2010
- Author(s)
  谷本圭司, 他
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Analysis of HIF-1-transgenic mice2010
- Author(s)
  谷本圭司
- Organizer
  International Symposium on the Innovation for Health and Sustainable Life
- Place of Presentation
  Hiroshima
- Year and Date
  2010-03-09
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Alteration of the DNA repair system in hypoxic cancer cells.2010
- Author(s)
  Keiji Tanimoto, Hideaki Nakamura, Masahiko Nishiyama, Eiso Hiyama, Keiko Hiyama.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Molecular mechanisms of regulation of the pVHL by oncogenic UBE2S/E2-EPF2010
- Author(s)
  谷本圭司, 他
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] 低酸素下がん細胞におけるDNA損傷応答抑制機構2010
- Author(s)
  谷本圭司, 中村秀明, 河本健, 加藤幸夫, 檜山英三, 西山正彦, 檜山桂子
- Organizer
  第53回放射線影響学会
- Place of Presentation
  京都
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] 低酸素下がん細胞におけるDNA損傷応答抑制機構2010
- Author(s)
  谷本圭司, 他
- Organizer
  第53回放射線影響学会
- Place of Presentation
  京都テルサ
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Analysis of HIF-1-transgenic mice2010
- Author(s)
  谷本圭司?
- Organizer
  International Symposium on the Innovation for Health and Sustainable Life
- Place of Presentation
  Hiroshima
- Year and Date
  2010-03-09
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] Zoledronate inhibits HIF-1α in cancer cells2009
- Author(s)
  谷本圭司
- Organizer
  第7回がんとハイポキシア研究会
- Place of Presentation
  京都
- Year and Date
  2009-12-06
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] Molecular mechanisms of degradation of the pVHL, tumor suppressor gene product, by a novel oncogenic protein, UBE2S.2009
- Author(s)
  Keiji Tanimoto, Hideaki Nakamura, Shoichi Fumoto, Eiso Hiyama, Hidetaka Eguchi, Masahiko Nishiyama, Keiko Hiyama.
- Organizer
  100^<th> Annual Meeting of Am. Assoc. Cancer Res, Denver
- Place of Presentation
  Colorado
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Molecular mechanisms of degradation of the pVHL, tumor suppressor gene product, by a novel oncogenic protein, UBE2S2009
- Author(s)
  谷本圭司
- Organizer
  Am.Assoc.Cancer Res 100^<th> Annual Meeting 2009
- Place of Presentation
  Denver
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] HIF1Aトランスジェニックマウスの腫瘍原性解析2009
- Author(s)
  谷本圭司
- Organizer
  博多シンポジウム「内・外環境と生物応答」
- Place of Presentation
  博多
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Diagnostic factors in cancers.2009
- Author(s)
  Tanimoto K.
- Organizer
  The 7^<th> Scientific Respiratory Medicine Meeting PIPKRA2009
- Place of Presentation
  Jakarta, Indonesia
- Year and Date
  2009-02-14
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Molecular mechanisms of degradation of the pVHL, tumor suppressor gene product, by a novel oncogenic protein, UBE2S2009
- Author(s)
  谷本圭司
- Organizer
  Am. Assoc. Cancer Res 100^<th> Annual Meeting 2009
- Place of Presentation
  Denver, USA
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Molecular mechanisms of anti-cancer activity of zoledronate2009
- Author(s)
  谷本圭司
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] DNA修復能に影響を与える生体内環境因子:低酸素環境2009
- Author(s)
  谷本圭司
- Organizer
  第50回原子爆弾後障害研究会
- Place of Presentation
  広島
- Year and Date
  2009-06-07
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] DNA修復能に影響を与える生体内環境因子 : 低酸素環境2009
- Author(s)
  谷本圭司
- Organizer
  第50回原子爆弾後障害研究会
- Place of Presentation
  広島
- Year and Date
  2009-06-07
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] ビスフォスフォネート製剤の抗腫瘍効果分子機構の解明2009
- Author(s)
  谷本圭司, 佐治重衡, 江口英孝, 和田智, 西山正彦, 檜山英三, 小田千代, 檜山桂子
- Organizer
  第10回ホルモンと癌研究会
- Place of Presentation
  仙台
- Year and Date
  2009-07-31
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Hypoxic signaling in cancers.2009
- Author(s)
  Tanimoto K.
- Organizer
  The 7^<th> Scientific Respiratory Medicine Meeting PIPKRA2009
- Place of Presentation
  Jakarta, Indonesia
- Year and Date
  2009-02-15
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] HIF1Aトランスジェニックマウスの腫瘍原性解析2009
- Author(s)
  谷本圭司
- Organizer
  博多シンポジウム「内・外環境と生物応答」
- Place of Presentation
  博多
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] Molecular mechanisms of anti-cancer activity of zoledronate2009
- Author(s)
  谷本圭司
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] ビスフォスフォネート製剤の抗腫瘍効果分子機構の解明2009
- Author(s)
  谷本圭司
- Organizer
  第10回ホルモンと癌研究会
- Place of Presentation
  仙台
- Year and Date
  2009-07-31
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] Molecular mechanisms of degradation of the pVHL, tumor suppressor gene product, by a novel oncogenic protein, UBE2S. Am. Assoc. Cancer Res2009
- Author(s)
  Keiji Tanimoto
- Organizer
  100^<th> Annual Meeting 2009
- Place of Presentation
  Denver, CO, USA
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-21591706
[Presentation] Diagnostic factors in cancers.2009
- Author(s)
  Keiji Tanimoto, Keiko Hiyama, K.
- Organizer
  Satellite Symposium, The 7^<th> Scientific Respiratory Medicine Meeting PIPKRA2009
- Place of Presentation
  Jakarta, Indonesia
- Year and Date
  2009-02-14
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Zoledronate inhibits HIF-1α in cancer cells2009
- Author(s)
  谷本圭司
- Organizer
  第7回がんとハイポキシア研究会
- Place of Presentation
  京都
- Year and Date
  2009-12-06
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] Hypoxic signaling in cancers.2009
- Author(s)
  Keiji Tanimoto, Keiko Hiyama, K.
- Organizer
  Plenary Symposium, The 7^<th> Scientific Respiratory Medicine Meeting PIPKRA2009
- Place of Presentation
  Jakarta, Indonesia
- Year and Date
  2009-02-15
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] がん細胞における低酸素誘導性EFEMP機能解析.2008
- Author(s)
  谷本圭司
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] E2-EPF/UBE2Sによる癌抑制遺伝子産物pVHL制御機構2008
- Author(s)
  谷本圭司, 中村秀明, 麓祥一, 檜山英三, 江口英孝, 西山正彦, 檜山桂子
- Organizer
  第67回日本癌学会,学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] がん細胞における低酸素誘導性EFEMP2機能解析2008
- Author(s)
  谷本圭司, 中村秀明, 麓祥一, 檜山英三, 西山正彦, 檜山桂子
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] HIF-1-DEC経路によるDNA修復遺伝子発現制御.2008
- Author(s)
  谷本圭司
- Organizer
  第12回がん分子標的治療研究会総会
- Place of Presentation
  東京
- Year and Date
  2008-06-27
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] がんの生物学2008
- Author(s)
  谷本圭司
- Organizer
  第1回がん治療認定医制度のための教育セミナー
- Place of Presentation
  別府
- Year and Date
  2008-01-23
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] HIF-1-DEC pathway regulates expressions of DNA repair genes.2008
- Author(s)
  Keiji Tanimoto, Hideaki Nakamura, Shoichi Fumoto, Eiso Hiyama, Koji Yoshiga, Hidetaka Eguchi, Masahiko Nishiyama, Keiko Hiyama.
- Organizer
  Annual Meeting of Am. Assoc. Cancer Res 2008
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2008-04-14
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] HIF-1-DEC pathway regulates expressions of DNA repair genes.2008
- Author(s)
  Tanimoto K.
- Organizer
  Annual Meeting of Am. Assoc. Cancer Res 2008
- Place of Presentation
  San Diego, USA
- Year and Date
  2008-04-14
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] E2-EPF/UBE2Sによる癌抑制遺伝子産物pVHL制御機構.2008
- Author(s)
  谷本圭司
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] HIF-1-DEC経路によるDNA修復遺伝子発現制御2008
- Author(s)
  谷本圭司, 江口英孝, 西山正彦, 檜山桂子
- Organizer
  第12回がん分子標的治療研究会総会
- Place of Presentation
  東京
- Year and Date
  2008-06-27
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] 低酸素下口腔癌細胞におけるHIF-1-DEC機構の意義.2008
- Author(s)
  谷本圭司
- Organizer
  第53回日本口腔外科学会総会
- Place of Presentation
  徳島
- Year and Date
  2008-10-20
- Data Source
  KAKENHI-PROJECT-20592335
[Presentation] 低酸素下口腔癌細胞におけるHIF-1-DEC1機構の意義2008
- Author(s)
  谷本圭司, 吉賀浩二
- Organizer
  第53回日本口腔外科学会総会
- Place of Presentation
  徳島
- Year and Date
  2008-10-20
- Data Source
  KAKENHI-PROJECT-20592335

1. YOSHIGA Koji (70112216)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. NOGUCHI Tsuyoshi (20264335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. FUMOTO Shoichi (00532631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. KITANO Seigo (90169871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ETOH Tsuyoshi (00404369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HIYAMA Keiko (60253069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. BHAWAL Ujjal (50433339)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Sakamoto Takako (80196089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 林慎一 (60144862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 廣橋伸之 (30218862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SATO Fuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. WANG Bing

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. バワールウジャール

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 桧山英三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 河合秀彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 桧山桂子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 牧野雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 森田明典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 青木伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 弓削類

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 廣田喜一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 松尾禎之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanimoto Keiji 谷本 圭司

TANIMOTO Keiji 谷本 圭司

Research Projects

Research Products

Co-Researchers

Hypoxia Inducible Factor-Proline Hydroxylase (HIF-PH) Inhibitors as a Treatment Strategy for Combined Radiation Injury

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HIF-DEC下流のクリティカル遺伝子を標的としたがん治療分子標的治療法の開発Principal Investigator

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Development of a molecular targeting anti-cancer therapy against hypoxia inducible DEC transcription factorsPrincipal Investigator

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Novel therapeutic and preventive strategy of resveratrol treatment in triple negative breast cancer cells

Principal Investigator

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Functions of a novel hypoxia-inducible reprogramming factor GLIS1 in cancer cellsPrincipal Investigator

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Molecular mechanisms of DEC-Twist transcription factors in oral squamous cell carcinoma

Principal Investigator

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The roles of HIF-DEC pathway on DNA repair systems in hypoxic oral cancer cells.Principal Investigator

Principal Investigator

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Identification of EMP3 as a tumor suppressor gene for esophageal squamous cell carcinoma and elucidation of its regulation mechanism.

Principal Investigator

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口腔癌細胞における新規低酸素誘導遺伝子EFEMP2機能解析Principal Investigator

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口腔癌低酸素領域における抗癌剤および放射線耐性機構の解明Principal Investigator

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プロテオミクス法によるHIF-1α複合体精製および口腔癌細胞における機能解析Principal Investigator

Principal Investigator

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Research Institution

活性型低酸素応答性転写因子HIF-1α遺伝子導入マウスの作製および解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of inhibitory effect on hypoxia-inducible transcriptional activities.

Principal Investigator

Project Period (FY)

Tanimoto Keiji 谷本圭司

TANIMOTO Keiji 谷本圭司