TAKEDA Kenji 竹田健史

Researcher Number	90340009
Other IDs
External Links
Affiliation (Current)	2025: 金沢医科大学, 総合医学研究所, 講師 2025: 金沢医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 金沢医科大学, 総合医学研究所, 助教 2023: 金沢医科大学, 医学部, 助教 2020 – 2021: 金沢医科大学, 医学部, 助教 2007 – 2009: 金沢医科大学, 医学部, 助教 2005 – 2006: 金沢医科大学, 医学部, 助手 2002 – 2003: 金沢医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Circulatory organs internal medicine / Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine / Basic Section 53020:Cardiology-related
Keywords	Principal Investigator ユビキチン / プロテオスタシス / GA-AGEs / Kmur / タンパク分解 / 細胞内タンパク質品質管理 / AGEs / 細胞内タンパク質品質管理機構 / CHK1 / Mule … More / estrogen receptor / coronary risk factor / Androgen / Estrogen / 遺伝子 / エストロゲン受容体 / 冠危険因子 / アンドロゲン / エストロゲン / RALT / HB-EGF / 心肥大 / 負の制御因子 / 酸化ストレス / 03 / 2014 / Ralt / Mig-6 / 心筋細胞 / 蛋白質間相互作用 / 分子心臓病態学 … More Except Principal Investigator 心不全 / heart failure / ERK / 肥満 / 心筋肥大 / アディポネクチン / 心筋炎 / 不耐 / 遺伝子異常 / 筋障害 / スタチン / in situ hybridization / obesity / adiponectin / myocarditis / angiotensin II receptor / 再生 / 心筋 / アンギオテンシン受容体 / 心臓肥大 / アンギオテンシン受容 / ARB / angiotensin II / cardiac hypertrophy / mechanical stress / inverse agonist / cardiomyocyte / AngII 1型受容体拮抗薬(ARB) / アンジオテンシンII / AngII 1型受容体拮抗藥(ARB) / インバースアゴニスト活性 / AngII1型受容体拮抗薬 / AngII / 心肥大 / メカニカルストレス / インパースアゴニスト / 心筋細胞 / マウス / 糖尿病 / アンギオテンシン / 再生医療 / サイトカイン Less

高血糖下で蓄積する毒性AGEsの新規内在性クリアランス機構の解明Principal Investigator
- Principal Investigator
  
  竹田健史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kanazawa Medical University
Molecular mechanism of complete statin intolerance in Japanese
- Principal Investigator
  
  梶波康二
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kanazawa Medical University
Analysis of the regulation mechanism of CHK1 by Mule during myocardial stress responsePrincipal Investigator
- Principal Investigator
  
  TAKEDA Kenji
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kanazawa Medical University
Role of Gene33/RALT in oxidative stress-induced signal transduction in cardiac cells.Principal Investigator
- Principal Investigator
  
  TAKEDA Kenji
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kanazawa Medical University
Carddiac remodeling therapy due to induced expression by cardiac adiponectin
- Principal Investigator
  
  KANDA Tugiyasu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kanazawa Medical University
Inverse agonist activity of angiotensin II type 1 receptor blockers
- Principal Investigator
  
  AKAZAWA Sumiyo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kanazawa Medical University
Therapeutic adaptation of cardiac expression of adiponectin
- Principal Investigator
  
  KANDA Tsugiyasu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kanazawa Medical University
Female sex hormone-hormone receptor system as a coronary risk factorPrincipal Investigator
- Principal Investigator
  
  TAKEDA Kenji, KAJINAMI Kouji
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KANAZAWA MEDICAL UNIVERSITY

All 2024 2023 2020 2009 2008

All Journal Article Presentation

[Journal Article] Structures of Toxic Advanced Glycation End-Products Derived from Glyceraldehyde, A Sugar Metabolite2024
- Author(s)
  Sakai-Sakasai Akiko、Takeda Kenji、Suzuki Hirokazu、Takeuchi Masayoshi
- Journal Title
  
  Biomolecules
  
  Volume: 14 Issue: 2 Pages: 202-202
- DOI
  10.3390/biom14020202
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08410, KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21H04865
[Journal Article] A Novel Approach: Investigating the Intracellular Clearance Mechanism of Glyceraldehyde-Derived Advanced Glycation End-Products Using the Artificial Checkpoint Kinase 1 d270KD Mutant as a Substrate Model2023
- Author(s)
  Takeda Kenji、Sakai-Sakasai Akiko、Kajinami Kouji、Takeuchi Masayoshi
- Journal Title
  
  Cells
  
  Volume: 12 Issue: 24 Pages: 2838-2838
- DOI
  10.3390/cells12242838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08139, KAKENHI-PROJECT-20K08410, KAKENHI-PROJECT-21K11583, KAKENHI-PROJECT-21H04865
[Journal Article] Regulation of Positive Feedback Loop of HB-EGF Signal by Gene33/Ralt in H9c2 cells.2008
- Author(s)
  Kenji Takeda
- Journal Title
  
  Journal of Kanazawa Medical University 33
  
  Pages: 76-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790557
[Journal Article] Regulation of Positive Feedback Loop of HB-EGF Signal by Gene33/Ralt in H9c2 cells.2008
- Author(s)
  Takeda K, Akazwa S, Kawai Y, Kajinami K
- Journal Title
  
  J.Kanazawa Med.Univ. 33
  
  Pages: 76-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790557
[Presentation] 新規アプローチ：人工CHK1変異体d270KDを基質モデルとした毒性AGEs（TAGE）の細胞内クリアランス機構の解明.2023
- Author(s)
  竹田健史　坂井亜紀子　梶波康二　竹内正義
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K08410
[Presentation] HECT型ユビキチンリガーゼMuleはC末端欠損型Chk1の不活性型変異特異的な迅速分解機構に関与する2020
- Author(s)
  竹田健史、河合康幸、梶波康二
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K08410
[Presentation] Ralt interacts with 14-3-3 proteins in H9c2 cells.2009
- Author(s)
  Kenji Takeda, Yasuhito Ishigaki, Yasuyuki Kawai, Kouji Kajinami
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20790557
[Presentation] Ralt interacts with 14-3-3 proteins in H9c2 cells2009
- Author(s)
  竹田健史
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20790557
[Presentation] Gene33は、H9c2細胞においてHB-EGFシグナルの負のフィードバック制御因子として働く2008
- Author(s)
  竹田健史, 河合康幸, 梶波康二
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20790557
[Presentation] Gene33は、Hgc2細胞においてHB-EGFシグナルの負のフィードバック制御因子として働く2008
- Author(s)
  竹田健史
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20790557

1. KAJINAMI Kouji (40262563)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. KANDA Tugiyasu (40261838)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. AKAZAWA Sumiyo (80340016)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KOMURO Issei (30260483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OKUBO Shinji (50213658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. AKAZAWA Hiroshi (20396683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAKEDA Kenji 竹田 健史

Research Projects

Research Products

Co-Researchers

高血糖下で蓄積する毒性AGEsの新規内在性クリアランス機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of complete statin intolerance in Japanese

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the regulation mechanism of CHK1 by Mule during myocardial stress responsePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of Gene33/RALT in oxidative stress-induced signal transduction in cardiac cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Carddiac remodeling therapy due to induced expression by cardiac adiponectin

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Inverse agonist activity of angiotensin II type 1 receptor blockers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Therapeutic adaptation of cardiac expression of adiponectin

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Female sex hormone-hormone receptor system as a coronary risk factorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Structures of Toxic Advanced Glycation End-Products Derived from Glyceraldehyde, A Sugar Metabolite2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Novel Approach: Investigating the Intracellular Clearance Mechanism of Glyceraldehyde-Derived Advanced Glycation End-Products Using the Artificial Checkpoint Kinase 1 d270KD Mutant as a Substrate Model2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of Positive Feedback Loop of HB-EGF Signal by Gene33/Ralt in H9c2 cells.2008

Author(s)

Journal Title

Data Source

[Journal Article] Regulation of Positive Feedback Loop of HB-EGF Signal by Gene33/Ralt in H9c2 cells.2008

Author(s)

Journal Title

Data Source

[Presentation] 新規アプローチ：人工CHK1変異体d270KDを基質モデルとした毒性AGEs（TAGE）の細胞内クリアランス機構の解明.2023

Author(s)

Organizer

Data Source

[Presentation] HECT型ユビキチンリガーゼMuleはC末端欠損型Chk1の不活性型変異特異的な迅速分解機構に関与する2020

Author(s)

Organizer

Data Source

[Presentation] Ralt interacts with 14-3-3 proteins in H9c2 cells.2009

Author(s)

TAKEDA Kenji 竹田健史