TOH Kazuko 藤加珠子

… Alternative Names

藤加珠子トウカズコ

藤和珠子トウカズコ

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Researcher Number	90342732
Affiliation (Current)	2022: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2022: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, 研究員 2017: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), ナノ医療イノベーションセンター, 研究員 2016: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), 川崎市産業振興財団, 研究員 2015: 公益財団法人川崎市産業振興財団(ナノ医療イノベーションセンター), その他部局等, 研究員 2013 – 2014: 東京大学, 医学(系)研究科(研究院), 研究員 … More 2012: 東京大学, 医学(系)研究科(研究院), 特任研究員 2004: (財)山形県産業技術振興機構, 生物ラジカル研究所, 研究員 2003: 財団法人山形県産業技術振興機構, 生物ラジカル研究所, 研究員 Less
Review Section/Research Field	Principal Investigator Environmental technology/Environmental materials / Applied pharmacology / Tumor therapeutics Except Principal Investigator Basic Section 90120:Biomaterials-related / Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator ドラッグデリバリーシステム / リグニン / 超臨界 / 亜臨界 / 腸内細菌 / 機能性食品 / 紫外線吸収剤 / 植物性廃棄物 / 酸化防止剤 / ポリエチレングリコール … More / ABC現象 / 生体内共焦点顕微鏡 / 生体内リアルタイム共焦点顕微鏡 / 生体内リアルタイム蛍光共焦点顕微鏡 / 腫瘍深部イメージング … More Except Principal Investigator NanoMedicine / Glioblastoma / 核酸医薬デリバリー / ナノ医薬 / 機能性核酸 Less

Developing Nanomedicine that targets cellular heterogeneity for Complete Glioblastoma Remission
- Principal Investigator
  
  Quader Sabina
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
脳疾患部位を標的とする先端的核酸デリバリー技術の確立と脳疾患治療への挑戦
- Principal Investigator
  
  宮田完二郎
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Evaluation of tumor heterogeneity by deep tumor imaging and control of drug delivery systemPrincipal Investigator
- Principal Investigator
  
  Toh Kazuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kawasaki Institute of Industrial Promotion Innovation Center of NanoMedicine
Elucidation and evasion of the immunogenicity induced by the repeated administration of the PEGylated nanocarrierPrincipal Investigator
- Principal Investigator
  
  TOH Kazuko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  The University of Tokyo
亜臨界及び超臨界流体を用いたリグニンの改質による未利用植物資源有効利用技術の開発Principal Investigator
- Principal Investigator
  
  藤加珠子 (藤和珠子)
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Environmental technology/Environmental materials
- Research Institution
  Yamagata Research Institute of Technology
  Yamagata Public Corporation For the Development Of Industry, Institute Life Support Technology

All 2014 2013 2012 2005 2003

All Journal Article Presentation

[Journal Article] Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors.2014
- Author(s)
  Z. Ge, Q. Chen, K. Osada, X. Liu, T. A. Tockary, S. Uchida, A. Dirisala, T. Ishii, T. Nomoto, K. Toh, Y. Matsumoto, M. Oba, M. R. Kano, K. Itaka, K. Kataoka
- Journal Title
  
  Biomaterials.
  
  Volume: 35 Pages: 3416-3426
- DOI
  10.1016/j.biomaterials.2013.12.086
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-23790433, KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011, KAKENHI-PROJECT-26293119, KAKENHI-PROJECT-26670738
[Journal Article] Multifunctional polyion complex micelle featuring enhanced stability, targetability, and endosome escapability for systemic siRNA delivery to subcutaneous model of lung cancer.2014
- Author(s)
  Hyun Jin Kim, Takehiko Ishii, Meng Zheng, Sumiyo Watanabe, Kazuko Toh, Yu Matsumoto, Nobuhiro Nishiyama, Kanjiro Miyata, Kazunori Kataoka
- Journal Title
  
  Drug Deliv. Transl.Res.
  
  Volume: 4 Pages: 50-60
- DOI
  10.1007/s13346-013-0175-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13F03349, KAKENHI-PROJECT-23390009, KAKENHI-PROJECT-23790043, KAKENHI-PROJECT-24659411, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141, KAKENHI-PROJECT-26670738
[Journal Article] Multicompartment Micelles with Adjustable Poly(ethylene glycol) Shell for Efficient in Vivo Photodynamic Therapy2014
- Author(s)
  Christopher V. Synatschke, Takahiro Nomoto, Horacio Cabral, Melanie Förtsch, Kazuko Toh, Yu Matsumoto, Kozo Miyazaki, Andreas Hanisch, Felix H. Schacher, Akihiro Kishimura, Nobuhiro Nishiyama, Axel H. E. Müller, and Kazunori Kataoka
- Journal Title
  
  ACS NANO
  
  Volume: 8(2) Pages: 1161-1172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790530
[Journal Article] Tethered PEG crowdedness determining shape and blood circulation profile of polyplex micelle gene carriers.2013
- Author(s)
  Theofilus A. Tockary, Kensuke Osada, Qixian Chen, Kaori Machitani, Anjaneyulu Dirisala, Satoshi Uchida, Takahiro Nomoto, Kazuko Toh, Yu Matsumoto, Keiji Itaka, Koji Nitta, Kuniaki Nagayama, and Kazunori Kataoka
- Journal Title
  
  Macromolecules
  
  Volume: 46 Pages: 6585-6592
- DOI
  10.1021/ma401093z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300170, KAKENHI-PROJECT-24790530, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25882011
[Journal Article] Evaluation of the Dynamics of Drug Delivery Systems (DDS) Using Intravital Real-Time Confocal Laser Scanning Microscopy2012
- Author(s)
  野本貴大、松本　有、藤　加珠子、R. James Christie、宮田完二郎、大庭　誠、Horacio Cabral、村上真美、福島重人、西山伸宏、片岡一則
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 132 Issue: 12 Pages: 1347-1354
- DOI
  10.1248/yakushi.12-00234-1
- NAID
  130002489530
- ISSN
  0031-6903, 1347-5231
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790530
[Journal Article] Evaluation of the Ability of Aqueous Lignin-Carbohydrate Complex Extracted from Botanical Waste to Scavenge Reactive Oxygen Species by Using Electron spin Resonance Method2005
- Author(s)
  藤加珠子
- Journal Title
  
  Wood and Fiber Science 37(2)(印刷中)
- Data Source
  KAKENHI-PROJECT-15710070
[Journal Article] 植物性廃棄物由来リグニンの抽出と機能性評価2003
- Author(s)
  藤加珠子
- Journal Title
  
  平成15年度生物ラジカル研究年報
  
  Pages: 13-13
- Data Source
  KAKENHI-PROJECT-15710070
[Presentation] Intravital confocal microscopy assay for the evaluation of antioxidant capacity2014
- Author(s)
  Yu Matsumoto, Kazuko Toh, Kazunori Kataoka and Tatsuya Yamasoba
- Organizer
  37th ARO MidWinter Meeting
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-24790530
[Presentation] Förster Resonance Energy Transferと生体内顕微鏡を用いたintact siRNAの定量的評価法の開発2013
- Author(s)
  藤　加珠子, 野本　貴大, 松本　有, 渡邉　秀美代, 福島　重人, 茶谷　洋行, R. James Christie, 宮田　完二郎, 西山　伸宏, 片岡　一則
- Organizer
  第35回日本バイオマテリアル学会大会
- Place of Presentation
  東京都江戸川区船堀4-1-1 タワーホール船堀
- Data Source
  KAKENHI-PROJECT-24790530
[Presentation] Intravital Monitoring of Intact siRNA Using Fluorescence Resonance Energy Transfer2013
- Author(s)
  Kazuko Toh, Takahiro Nomoto, Yu Matsumoto, Sumiyo Watanabe, Shigeto Fukushima, Hiroyuki Chaya, R. James Christie, Kanjiro Miyata, Nobuhiro Nishiyama, Kazunori Kataoka
- Organizer
  40th annual meeting & exposition of the Controlled Release Society
- Place of Presentation
  Honolulu, Hawaii, U. S. A.
- Data Source
  KAKENHI-PROJECT-24790530

1. Quader Sabina (90749699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 宮田完二郎 (50436523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 谷口陽祐 (00452714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 林光太朗 (00780660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MATSUMOTO Yu

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. KANO Mitsunobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. ISHII Takehiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. OSADA Kensuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. WATANABE Sumiyo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 位高啓史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 津本浩平

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
12. 片岡一則

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
13. 内田智士

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. ZHENG Meng

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
15. 西山伸宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TOH Kazuko 藤 加珠子

藤 加珠子 トウ カズコ

藤 和珠子 トウ カズコ

Research Projects

Research Products

Co-Researchers

Developing Nanomedicine that targets cellular heterogeneity for Complete Glioblastoma Remission

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳疾患部位を標的とする先端的核酸デリバリー技術の確立と脳疾患治療への挑戦

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of tumor heterogeneity by deep tumor imaging and control of drug delivery systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation and evasion of the immunogenicity induced by the repeated administration of the PEGylated nanocarrierPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

亜臨界及び超臨界流体を用いたリグニンの改質による未利用植物資源有効利用技術の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multifunctional polyion complex micelle featuring enhanced stability, targetability, and endosome escapability for systemic siRNA delivery to subcutaneous model of lung cancer.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multicompartment Micelles with Adjustable Poly(ethylene glycol) Shell for Efficient in Vivo Photodynamic Therapy2014

Author(s)

Journal Title

Data Source

[Journal Article] Tethered PEG crowdedness determining shape and blood circulation profile of polyplex micelle gene carriers.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of the Dynamics of Drug Delivery Systems (DDS) Using Intravital Real-Time Confocal Laser Scanning Microscopy2012

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Evaluation of the Ability of Aqueous Lignin-Carbohydrate Complex Extracted from Botanical Waste to Scavenge Reactive Oxygen Species by Using Electron spin Resonance Method2005

Author(s)

Journal Title

Data Source

[Journal Article] 植物性廃棄物由来リグニンの抽出と機能性評価2003

Author(s)

Journal Title

Data Source

[Presentation] Intravital confocal microscopy assay for the evaluation of antioxidant capacity2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Förster Resonance Energy Transferと生体内顕微鏡を用いたintact siRNAの定量的評価法の開発2013

Author(s)

Organizer

Place of Presentation

TOH Kazuko 藤加珠子

藤加珠子トウカズコ

藤和珠子トウカズコ