YAMAMOTO Megumi 山本恵

Researcher Number	90347170
External Links
Affiliation (based on the past Project Information) *help	2003 – 2005: Sapporo Med.Univ.Sch.Med., Dept.Neuropsychiatry, Assistant Prof., 医学部, 講師 2002 – 2003: 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Psychiatric science Except Principal Investigator Psychiatric science / Psychiatric science
Keywords	Principal Investigator 神経回路網 / 分化 / 脳由来神経栄養因子 / 神経幹細胞 / 動物モデル / 早期暴露 / エタノール / アルコール依存症 Except Principal Investigator BDNF / CREB … More / REST / NRSF / 神経幹細胞 / neural stem cell / 神経新生 / エタノール / ERK / ApoE / アルコール依存 / 神経栄養因子 / NF-κB / アネキシンIV / cAMP / transplantation / cultured cell / neural network / depression / mood stabilizer / antidepressant / 移植 / 培養細胞 / 神経回路網 / うつ病 / 気分安定薬 / 抗うつ薬 / ethanol / Lithium / IGF-1 / 分化 / 増殖 / Akt / BONF / regenerative medicine / neurogenesis / fetal alcohol syndrome / alcohol damage / リン酸化Erk / リン酸化Akt / MAP2 / 再生医療 / 胎児性アルコール症候群 / アルコール障害 / NF κ-B / annexin IV / Alzheimer's disease / alcohol dependence / アポトーシス / 脂質代謝異 / アルコール性痴呆 / NF-κ / アルツハイマー病 / Neural stem cell / Neurotrophic factor / NE-κB / AnnexinIV / Alcohol dependence / SH-SY5Y細胞 / NFκB / Ca^<2+>-結合蛋白質 / Ca^<2+> / アルコール / c-AMP / アルコール依存症 Less

The alteration of adult neural network by pre/post-natal alcohol and addictive drug exposure
- Principal Investigator
  
  SAITO Toshikazu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Sapporo Medical University
Study on the cognitive and behavioral consequences of prenatal or early developmental exposure of the brain to ethanol
- Principal Investigator
  
  IKEDA Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Sapporo Medical University
Study on implication of neurogenesis and neural network disruption in the pathophysiology of depression.
- Principal Investigator
  
  HASHIMOTO Eri
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Sapporo Medical University
早期飲酒とアルコール依存症の発症と病態に関するポストゲノム研究Principal Investigator
- Principal Investigator
  
  山本恵
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Sapporo Medical University
The post-genomic research for the pathophysiology and treatment of alcohol and drug addictions.
- Principal Investigator
  
  SAITO Toshikazu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Sapporo Medical University
Does ethanol-induced lipid metabolism dysfunction aggravate symptoms of dementia?
- Principal Investigator
  
  IKEDA Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Sapporo Medical University

All 2005 2004

All Journal Article

[Journal Article] The effect of ethanol on cell fate determination of neural stem cells2005
- Author(s)
  Tateno M, Ukai W, Yamamoto M, Hashimoto E, Ikeda H, Saito T
- Journal Title
  
  Alcohol Clin Exp Res 29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] The effect of ethanol on cell fate determination of neural stem cells.2005
- Author(s)
  Tateno M, Ukai W, Yamamoto M, Hashimoto E, Ikeda H, Saito T.
- Journal Title
  
  Alcohol Clin Exp Res 29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] The effect of ethanol on cell fate determination of neural stem cells2005
- Author(s)
  Tateno M, Ukai W, Yamamoto M, Hashimoto E, Ikeda H, Saito T
- Journal Title
  
  Alcohol Clin Exp Res 29(12Suppl)
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] Attention of brain derived neurotrophic factor (BDNF) by ethanol and cytoprotective effect of exogenous BDNF against ethanol damage in neuronal cells2005
- Author(s)
  Sakai R, Ukai W, Sohma H, Hashimoto E, Yamamoto M, Ikeda H, Saito T
- Journal Title
  
  J Neural Transm 112(8)
  
  Pages: 1005-1013
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] Attenuation of brain derived neurotrophic factor (BDNF) by ethanol and cytoprotective effect of exogenous BDNF against ethanol damage in neuronal cells.2005
- Author(s)
  Sakai R, Ukai W, Sohma H, Hashimoto E, Yamamoto M, Ikeda H, Saito T.
- Journal Title
  
  J Neural Transm 112(8)
  
  Pages: 1005-1013
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] Attenuation of brain derived neurotrophic factor (BDNF) by ethanol and cytoprotective effect of exogenous BDNF against ethanol damage in neuronal cells2005
- Author(s)
  Sakai R, Ukai W, Sohma H, Hashimoto E, Yamamoto M, Ikeda H, Saito T
- Journal Title
  
  J Neural Transm 112(8)
  
  Pages: 1005-1005
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] Ethanol inhibition of neural stem cell differentiation is reduced by neurotrophic factors.2004
- Author(s)
  Tateno M, Ukai W, Ozawa H, Yamamoto M, Toki S, Ikeda H, Saito T.
- Journal Title
  
  Alcohol Clin Exp Res 28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] 依存症のニューロサイエンスアルコール依存の神経生物学2004
- Author(s)
  山本恵
- Journal Title
  
  CliniCal Neuroscience 22・6
  
  Pages: 670-672
- Data Source
  KAKENHI-PROJECT-15790631
[Journal Article] Decreased expression of PCP4/PEP19 in the prefrontal cortex of alcoholics revealed by oligonucleotide microarray analysis2004
- Author(s)
  Iwamoto, K., Bundo, M., Yamamoto, M., Ozawa, H., Saito, T., Kato, T
- Journal Title
  
  Neurosci Res 49(4)
  
  Pages: 379-385
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] エタノールによる神経幹細胞内シグナル変化と分化制御2004
- Author(s)
  館農勝, 鵜飼渉, 山本恵, 橋本恵理, 池田官司, 齋藤利和
- Journal Title
  
  アルコールと医学生物学 24
  
  Pages: 61-65
- NAID
  10013456330
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] エタノールによる脳内神経回路網改変の可能性エタノールの神経細胞の新生及び生存に与える影響2004
- Author(s)
  山本恵他
- Journal Title
  
  日本アルコール・薬物医学会雑誌 39・1
  
  Pages: 51-60
- Data Source
  KAKENHI-PROJECT-16390327
[Journal Article] 依存症のニューロサイエンスアルコール依存症の神経生物学2004
- Author(s)
  山本恵他
- Journal Title
  
  Clinical Neuroscience 22・6
  
  Pages: 670-672
- Data Source
  KAKENHI-PROJECT-16390327
[Journal Article] エタノールによる脳内神経回路網改変の可能性エタノールの神経細胞の新生及び生存に与える影響2004
- Author(s)
  山本恵
- Journal Title
  
  日本アルコール・薬物医学会雑誌 39・1
  
  Pages: 51-60
- Data Source
  KAKENHI-PROJECT-15790631
[Journal Article] The effects of antidepressants and moodstabilizers on the differentiation of neural stem cells2004
- Author(s)
  Ukai W, Ozawa H, Tateno M, Konno M, Yamamoto M, Ikeda H, Saito T
- Journal Title
  
  Methods Find Clin Pharmacol 26
  
  Pages: 115-125
- NAID
  10013403943
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] 依存性のニューロサイエンスアルコール依存症の神経生物学2004
- Author(s)
  山本恵他
- Journal Title
  
  Clinical Neuroscience 22・6
  
  Pages: 670-672
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] Ethanol inhibition of neural stem cell differentiation is reduced by neurotrophic factors2004
- Author(s)
  Tateno M, Ukai W, Ozawa H, Yamamoto M, Toki S, Ikeda H, Saito T
- Journal Title
  
  Alcohol Clin Exp Res 28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] Decreased expression of PCP4/PEP19 in the prefrontal cortex of alcoholics revealed by oligonucleotide microarray analysis.2004
- Author(s)
  Iwamoto, K., Bundo, M., Yamamoto, M., Ozawa, H., Saito, T., Kato, T.
- Journal Title
  
  Neurosci Res 49(4)
  
  Pages: 379-385
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] エタノールによる脳内神経回路網改変の可能性エタノールの神経細胞の新生及び生存に与える影響2004
- Author(s)
  山本恵他
- Journal Title
  
  日本アルコール・薬物医学会雑誌 39・1
  
  Pages: 51-60
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] The effects of ethanol on neuronal survival, differentiation and death.2004
- Author(s)
  Ozawa H, Ukai W, Tateno M, Konno M, Yamamoto M, Ikeda H, Saito T.
- Journal Title
  
  Methods Find Clin Pharmacol 26
  
  Pages: 95-98
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] The effects of ethanol on neuronal survival, differentiation and death2004
- Author(s)
  Ozawa H, Ukai W, Tateno M, Konno M, Yamamoto M, Ikeda H, Saito T
- Journal Title
  
  Methods Find Clin Pharmacol 26
  
  Pages: 95-98
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] 抗精神病薬の神経細胞障害性における定型と非定型抗精神病薬の違い2004
- Author(s)
  鵜飼渉, 館農勝, 山本恵, 橋本恵理, 池田官司, 小澤寛樹, 齋藤利和
- Journal Title
  
  臨床精神薬理 7
  
  Pages: 341-348
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] The effects of antidepressants and moodstabilizers on the differentiation of neural stem cells.2004
- Author(s)
  Ukai W, Ozawa H, Tateno M, Konno M, Yamamoto M, Ikeda H, Saito T.
- Journal Title
  
  Methods Find Clin Pharmacol 26
  
  Pages: 115-125
- NAID
  10013403943
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591147
[Journal Article] 神経幹細胞分化誘導能に及ぼす抗うつ薬の影響に関する研究2004
- Author(s)
  鵜飼渉, 館農勝, 山本恵, 橋本恵理, 池田官司, 小澤寛樹, 齋藤利和
- Journal Title
  
  精神薬寮研究年報 36
  
  Pages: 153-159
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591147

1. SAITO Toshikazu (50128518)

# of Collaborated Projects: 5 results

# of Collaborated Products: 17 results
2. SOHMA Hitoshi (70226702)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. IKEDA Hiroshi (30232193)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. HASHIMOTO Eri (30301401)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
5. OZAWA Hiroki (50260766)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KATO Tadafumi (30214381)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. UKAI Wataru (40381256)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. YOSHIDA Taku (60347169)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 池田宏司

# of Collaborated Projects: 0 results

# of Collaborated Products: 15 results
10. 鵜飼捗

# of Collaborated Projects: 0 results

# of Collaborated Products: 15 results

YAMAMOTO Megumi 山本 恵

Research Projects

Research Products

Co-Researchers

The alteration of adult neural network by pre/post-natal alcohol and addictive drug exposure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the cognitive and behavioral consequences of prenatal or early developmental exposure of the brain to ethanol

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on implication of neurogenesis and neural network disruption in the pathophysiology of depression.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

早期飲酒とアルコール依存症の発症と病態に関するポストゲノム研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The post-genomic research for the pathophysiology and treatment of alcohol and drug addictions.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Does ethanol-induced lipid metabolism dysfunction aggravate symptoms of dementia?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The effect of ethanol on cell fate determination of neural stem cells2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] The effect of ethanol on cell fate determination of neural stem cells.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] The effect of ethanol on cell fate determination of neural stem cells2005

Author(s)

Journal Title

Data Source

[Journal Article] Attention of brain derived neurotrophic factor (BDNF) by ethanol and cytoprotective effect of exogenous BDNF against ethanol damage in neuronal cells2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Attenuation of brain derived neurotrophic factor (BDNF) by ethanol and cytoprotective effect of exogenous BDNF against ethanol damage in neuronal cells.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Attenuation of brain derived neurotrophic factor (BDNF) by ethanol and cytoprotective effect of exogenous BDNF against ethanol damage in neuronal cells2005

Author(s)

Journal Title

Data Source

[Journal Article] Ethanol inhibition of neural stem cell differentiation is reduced by neurotrophic factors.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] 依存症のニューロサイエンス アルコール依存の神経生物学2004

Author(s)

Journal Title

Data Source

[Journal Article] Decreased expression of PCP4/PEP19 in the prefrontal cortex of alcoholics revealed by oligonucleotide microarray analysis2004

Author(s)

Journal Title

YAMAMOTO Megumi 山本恵

[Journal Article] 依存症のニューロサイエンスアルコール依存の神経生物学2004

[Journal Article] エタノールによる脳内神経回路網改変の可能性エタノールの神経細胞の新生及び生存に与える影響2004

[Journal Article] 依存症のニューロサイエンスアルコール依存症の神経生物学2004

[Journal Article] エタノールによる脳内神経回路網改変の可能性エタノールの神経細胞の新生及び生存に与える影響2004

[Journal Article] 依存性のニューロサイエンスアルコール依存症の神経生物学2004

[Journal Article] エタノールによる脳内神経回路網改変の可能性エタノールの神経細胞の新生及び生存に与える影響2004