HIRASHIMA CHIKAKO 平嶋周子

Researcher Number	90348011
Review Section/Research Field	Except Principal Investigator Obstetrics and gynecology
Keywords	Except Principal Investigator PlGF / sFlt-1 / 妊娠高血圧症候群 / sFlt-1/PlGF比 / 発症予知 / 妊娠高血圧腎症

Validation of the prediction of preeclampsia within 4 weeks using the onset threshold of plasma sFlt-1/PlGF ratio
- Principal Investigator
  
  Ohkuchi Akihide
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Jichi Medical University

All 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Prediction and prevention of hypertensive disorders of pregnancy.2017
- Author(s)
  Ohkuchi A, Hirashima C, Takahashi K, Suzuki H, Matsubara S.
- Journal Title
  
  Hypertens Res
  
  Volume: 40 Issue: 1 Pages: 5-14
- DOI
  10.1038/hr.2016.107
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592482
[Journal Article] The Frequency of Peripheral Blood CD4+FoxP3+ Regulatory T Cells in Women With Pre-eclampsia and Those With High-risk Factors for Pre-eclampsia.2015
- Author(s)
  Nagayama S, Ohkuchi A, Shirasuna K, Takahashi K, Suzuki H, Hirashima C, Sakata A, Nishimura S, Takahashi M, Matsubara S.
- Journal Title
  
  Hypertens Pregnancy
  
  Volume: 34 Issue: 4 Pages: 443-455
- DOI
  10.3109/10641955.2015.1065884
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592482
[Journal Article] Ambulatory BP monitoring and clinic BP in predicting small-for-gestational-age infants during pregnancy2015
- Author(s)
  Eguchi K, Ohmaru T, Ohkuchi A, Hirashima C, Takahashi K, Suzuki H, Kario K
- Journal Title
  
  J Hum Hypertens
  
  Volume: in press Issue: 1 Pages: 62-7
- DOI
  10.1038/jhh.2015.20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293192, KAKENHI-PROJECT-24592482
[Journal Article] A novel three-step approach for predicting the imminent onset of preeclampsia within 4 weeks after blood sampling at 19-31 weeks of gestation.2014
- Author(s)
  Hirashima C, Ohkuchi A, Takahashi K, Suzuki H, Matsubara S, Suzuki M.
- Journal Title
  
  Hypertens Res
  
  Volume: 37 Issue: 6 Pages: 519-525
- DOI
  10.1038/hr.2014.31
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592482
[Journal Article] Increased antiangiogenetic factors in severe proteinuria without hypertension in pregnancy: is kidney biopsy necessary?2014
- Author(s)
  Ohmaru T, Ohkuchi A, Muto S, Hirashima C, Matsubara S, Suzuki M
- Journal Title
  
  CEN Case Rep
  
  Volume: 3 Issue: 1 Pages: 86-89
- DOI
  10.1007/s13730-013-0092-z
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592482
[Journal Article] Prediction of Early-Onset Preeclampsia Using Uterine Artery Doppler2014
- Author(s)
  Akihide Ohkuchi, Kayo Takahashi, Chikako Hirashima, RieUsui, Shigeki Matsubara and Mitsuaki Suzuki
- Journal Title
  
  Med J Obset Gynecol
  
  Volume: 2 Pages: 1026-1026
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592482
[Journal Article] Prediction of Early-Onset Preeclampsia Using Angiogenesis-Related Factors2014
- Author(s)
  Chikako Hirashima, Akihide Ohkuchi, Kayo Takahashi, Rie Usui, Shigeki Matsubara and Mitsuaki Suzuki
- Journal Title
  
  Med J Obstet Gynecol
  
  Volume: 2 Pages: 1025-1025
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24592482
[Journal Article] Additive effects of mean blood pressure and bilateral notching in the second trimester on subsequent angiogenesis-related factors.2014
- Author(s)
  Hirashima C, Ohkuchi A, Takahashi K, Suzuki H, Matsuda Y, Matsubara S, Suzuki M
- Journal Title
  
  Hypertens Res
  
  Volume: 37 Issue: 1 Pages: 76-81
- DOI
  10.1038/hr.2013.88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592482
[Journal Article] Onset threshold of the plasma levels of soluble fms-like tyrosine kinase 1/placental growth factor ratio for predicting the imminent onset of preeclampsia within 4 weeks after blood sampling at 19-31 weeks of gestation.2013
- Author(s)
  Ohkuchi A, Hirashima C, Takahashi K, Suzuki H, Matsubara S, Suzuki M
- Journal Title
  
  Hypertens Res
  
  Volume: 36 Issue: 12 Pages: 1073-80
- DOI
  10.1038/hr.2013.95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592482
[Journal Article] Establishing reference values for mean notch depth index, pulsatility index and resistance index in the uterine artery at 16-23 weeks' gestation.2012
- Author(s)
  Takahashi K, Ohkuchi A, Hirashima C, Matsubara S, Suzuki M.
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 38 Issue: 11 Pages: 1275-85
- DOI
  10.1111/j.1447-0756.2012.01864.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592482
[Journal Article] Plasma level of hydroxysteroid (17-β) dehydrogenase 1 in the second trimester is an independent risk factor for predicting preeclampsia after adjusting for the effects of mean blood pressure, bilateral notching and plasma level of soluble fms-like tyrosine kinase 1/placental growth factor ratio.2012
- Author(s)
  Ohkuchi A, Ishibashi O, Hirashima C, Takahashi K, Matsubara S, Takizawa T, Suzuki M.
- Journal Title
  
  Hypertens Res
  
  Volume: 35 Issue: 12 Pages: 1152-1158
- DOI
  10.1038/hr.2012.109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390386, KAKENHI-PROJECT-24390383, KAKENHI-PROJECT-24592482
[Presentation] 糖尿病性慢性腎不全妊婦における透析中のsoluble fms-like tyrosine kinase (sFlt)-1変化2016
- Author(s)
  佐野実穂，森澤宏行，大口昭英，高橋宏典，平嶋周子，薄井里英，安藤明彦，森下義幸，松原茂樹
- Organizer
  第26回腎と妊娠研究会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2016-03-05
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] 妊娠高血圧腎症妊婦における赤血球膜脂肪酸のω9一価不飽和酸重量比率と血清PlGF濃度との正相関2016
- Author(s)
  小林真実，大口昭英，平嶋周子，高橋佳代，鈴木寛正，森澤宏行，松原茂樹
- Organizer
  第26回腎と妊娠研究会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2016-03-05
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] White coat hypertension in pregnancy: high incidence rates of gestational hypertension and preeclampsia2016
- Author(s)
  Ohkuchi A, Takahashi K, Hirashima C, Suzuki H, Nagayama S, Takahashi H, Eguchi K, Matsubara S.
- Organizer
  The XX World Congress of ISSHP
- Place of Presentation
  the Maksoud Plaza Hotel (Sao Paulo, Brazil)
- Year and Date
  2016-10-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] 家庭血圧測定における変曲点の在胎週数、血圧レベル、及び、その後2週間の血圧増加速度を用いた妊娠高血圧腎症並びに妊娠高血圧の発症予知2015
- Author(s)
  猿山美幸、大口昭英、高橋佳代、大丸貴子、平嶋周子、鈴木寛正、松原茂樹、鈴木光明
- Organizer
  第67回日本産科婦人科学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-04-12
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] 糖尿病家族歴と妊娠糖尿病、妊娠高血圧あるいは妊娠高血圧腎症発症との関係2015
- Author(s)
  永山志穂、高橋佳代、大口昭英、平嶋周子、猿山美幸、鈴木寛正、松原茂樹、鈴木光明
- Organizer
  第67回日本産科婦人科学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] 糖尿病家族歴、高血圧家族歴の妊娠糖尿病、妊娠高血圧、及び、妊娠高血圧腎症発症に及ぼす影響：多変量解析2015
- Author(s)
  永山志穂、高橋佳代、大口昭英、平嶋周子、猿山美幸、鈴木寛正、松原茂樹
- Organizer
  第39回日本産婦人科栄養・代謝研究会
- Place of Presentation
  東京医科歯科大学　MDタワー
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] 妊娠中期、後期前半の胎盤成長因子濃度とその後のSGA児及びsmall placenta発生との関連2015
- Author(s)
  平嶋周子、大口昭英、高橋佳代、鈴木寛正、松原茂樹、鈴木光明
- Organizer
  第67回日本産科婦人科学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] sFlt-1が異常高値を示した急性妊娠脂肪肝　症例報告2015
- Author(s)
  鈴木寛正，大口昭英，平嶋周子，高橋佳代，森澤宏行，永山志穂，高橋宏典，馬場洋介，桑田知之，薄井里英，渡辺　尚，松原茂樹
- Organizer
  第51回日本周産期・新生児医学会学術集会
- Place of Presentation
  ヒルトン福岡シーホーク
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] 妊娠中期の血清galectin-1低値と、妊娠高血圧腎症及び妊娠高血圧の発症リスク2015
- Author(s)
  鈴木寛正、平嶋周子、大口昭英、高橋佳代、永山志穂、高橋宏典、猿山美幸、薄井里英、松原茂樹、鈴木光明
- Organizer
  第67回日本産科婦人科学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-04-12
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] Prediction of preeclampsia using angiogenesis-reltaed factors or home blood pressure monitoring.2014
- Author(s)
  Ohkuchi A, HIrashima C, Saruyama M, Takahashi K, Ohmaru T, Suzuki H, Matsubara S, Suzuki M.
- Organizer
  Workshop on the 46th International Congress on Pathophysiology of Pregnancy.
- Place of Presentation
  Keio Plaza Hotel
- Year and Date
  2014-09-19
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] The existence of inflection point in home blood pressure monitoring at earlier gestational weeks in preeclampsia and gestational hypertension.2014
- Author(s)
  Saruyama M, Ohkuchi A, Takahashi K, Ohmaru T, Hirashima C, Suzuki H, Matsubara S, Suzuki M.
- Organizer
  46th International Congress on Pathophysiology of Pregnancy.
- Place of Presentation
  Keio Plaza Hotel
- Year and Date
  2014-09-19
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] 妊娠高血圧症候群既往歴は、血圧高値と子宮動脈血流速度異常とは独立した妊娠高血圧腎症の危険因子である2014
- Author(s)
  小林真実、高橋佳代、大口昭英、鈴木寛正、有賀治子、廣瀬典子、平嶋周子、松原茂樹、鈴木光明
- Organizer
  第66回日本産婦人科学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2014-04-19
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] 妊娠高血圧症候群と血管新生関連因子2014
- Author(s)
  大口昭英，鈴木寛正，平嶋周子，高橋佳代，松原茂樹，鈴木光明
- Organizer
  第29回日本生殖免疫学会総会・学術集会
- Place of Presentation
  伊藤国際学術研究センター
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] 妊娠中期、後期前半のsFlt-1/PIGF比、及び、soluble endoglinによる妊娠高血圧腎症発症リスク評価2014
- Author(s)
  平嶋周子, 大口昭英, 高橋佳代, 松原茂樹, 鈴木光明
- Organizer
  第35回日本妊娠高血圧学会
- Place of Presentation
  京王プラザ
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] THE ADDITIVE EFFECT OF PLASMA LEVELS OF SFLT-1/PLGF RATIO FOLLOWING THE RISK CLASSIFICATION USING BOTH BLOOD PRESSURE LEVELS AND UTERINE ARTERY BLOOD FLOW IMPEDANCE IN THE SECOND TRIMESTER ON THE LATER OCCURRENCE OF PREECLAMPSIA2012
- Author(s)
  Akihide Ohkuchi, Chikako Hirashima, Kayo Takahashi, Sigeki Matsubara, Mitsuaki Suzuki
- Organizer
  XVIII International Society for the Study of Hypertension in Pregnancy (ISSHP) World Congress
- Place of Presentation
  Geneva
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] 妊娠中の自由行動下血圧指標はSmall for Gestational Ageに関連している．
- Author(s)
  江口和男, 大丸貴子, 大口昭英, 平嶋周子, 高橋佳代, 鈴木寛正, 苅尾七臣, 松原茂樹, 鈴木光明
- Organizer
  第37回日本高血圧学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-24592482
[Presentation] Decreased circulating levels of galectin-1 in the second trimester as an independent risk factor for not only preeclampsia but also gestational hypertension.
- Author(s)
  Ohkuchi A, Hirashima C, Nagayama S, Suzuki H, Takahashi K, Matsubara S, Suzuki M.
- Organizer
  XIX International society for the study of hypertension in pregnancy (ISSHP) World Congress
- Place of Presentation
  Hilton – New Orleans Riverside
- Year and Date
  2014-10-26 – 2014-10-29
- Data Source
  KAKENHI-PROJECT-24592482

1. Ohkuchi Akihide (10306136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results
2. TAKAHASHI KAYO (00448854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
3. KARIO Kazuomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. EGUCHI Kazuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 瀧澤俊広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIRASHIMA CHIKAKO 平嶋 周子

Research Projects

Research Products

Co-Researchers

Validation of the prediction of preeclampsia within 4 weeks using the onset threshold of plasma sFlt-1/PlGF ratio

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Prediction and prevention of hypertensive disorders of pregnancy.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Frequency of Peripheral Blood CD4+FoxP3+ Regulatory T Cells in Women With Pre-eclampsia and Those With High-risk Factors for Pre-eclampsia.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ambulatory BP monitoring and clinic BP in predicting small-for-gestational-age infants during pregnancy2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel three-step approach for predicting the imminent onset of preeclampsia within 4 weeks after blood sampling at 19-31 weeks of gestation.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased antiangiogenetic factors in severe proteinuria without hypertension in pregnancy: is kidney biopsy necessary?2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prediction of Early-Onset Preeclampsia Using Uterine Artery Doppler2014

Author(s)

Journal Title

Data Source

[Journal Article] Prediction of Early-Onset Preeclampsia Using Angiogenesis-Related Factors2014

Author(s)

Journal Title

Data Source

[Journal Article] Additive effects of mean blood pressure and bilateral notching in the second trimester on subsequent angiogenesis-related factors.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Onset threshold of the plasma levels of soluble fms-like tyrosine kinase 1/placental growth factor ratio for predicting the imminent onset of preeclampsia within 4 weeks after blood sampling at 19-31 weeks of gestation.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishing reference values for mean notch depth index, pulsatility index and resistance index in the uterine artery at 16-23 weeks' gestation.2012

Author(s)

Journal Title

DOI

Data Source

Author(s)

Journal Title

DOI

Data Source

[Presentation] 糖尿病性慢性腎不全妊婦における透析中のsoluble fms-like tyrosine kinase (sFlt)-1変化2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 妊娠高血圧腎症妊婦における赤血球膜脂肪酸のω9一価不飽和酸重量比率と血清PlGF濃度との正相関2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] White coat hypertension in pregnancy: high incidence rates of gestational hypertension and preeclampsia2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

HIRASHIMA CHIKAKO 平嶋周子

[Presentation] sFlt-1が異常高値を示した急性妊娠脂肪肝　症例報告2015