kuwabara Tomoko 桑原知子

… Alternative Names

kuwabara tomoko 桑原知子

KUWABARA Tomoko 桑原知子

桑原知子クラバラトモコ

藁科知子ワラシナトモコ

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Researcher Number	90358391
Other IDs
Affiliation (Current)	2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員
Affiliation (based on the past Project Information) *help	2018 – 2023: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 2015: 国立研究開発法人産業技術総合研究所, 創薬基盤研究部門ステムセルバイオテクノロジーグループ, 主任研究員 2015: 国立研究開発法人産業技術総合研究所, 創薬基盤研究部門, 主任研究員 2014: 独立行政法人産業技術総合研究所, 幹細胞工学センター, 研究員 2012 – 2014: 独立行政法人産業技術総合研究所, 幹細胞工学研究センター, 主任研究員 … More 2011: 独立行政法人産業技術総合研究所, 幹細胞工学センター, 研究員 2010 – 2011: 独立行政法人産業技術総合研究所, 幹細胞工学研究センター, 研究員 2006 – 2008: 独立行政法人産業技術総合研究所, 器官発生工学研究ラボ, 研究員 2005: 独立行政法人産業技術総合研究所, ジーンファンクション研究センター・機能性RNA研究チーム, 研究チーム長 Less
Review Section/Research Field	Principal Investigator Basic Section 59020:Sports sciences-related / Neurochemistry/Neuropharmacology / Biological Sciences / Nerve anatomy/Neuropathology / Neuroscience in general / Biological Sciences Except Principal Investigator Sports science
Keywords	Principal Investigator 幹細胞 / 神経 / 神経幹細胞 / 神経疾患 / 脳 / 海馬 / 神経新生 / 転写因子 / 機能性RNA / ニッチ細胞 … More / 運動効果 / 中枢神経系 / 成体幹細胞 / 分化 / 細胞 / 筋萎縮 / 細胞分子 / 組織幹細胞 / サテライト細胞 / 骨格筋 / 老化 / 認知機能 / 神経科学 / サルコペニア / 糖尿病 / グリア / ストレス / うつ病 / ゲノム / ノンコーディング / 分化制御 / モジュレーターRNA / 神経分化 / REST / NRSF / NRSE … More Except Principal Investigator ストレス / GFAP / Wnt-3a / 成熟海馬 / LC-MS/MS / DHT / アンドロゲン / 軽運動 / タンパク質合成 / 脂質代謝 / 乳酸性作業閾値 / 換気性作業閾値 / IPA解析 / マイクロアレイ / ニューロステロイド / アストロサイト / 神経新生 / 認知機能 / 海馬 / 低強度運動 Less

Effects of physical exercise on the regulation of adult stem cells existed independently in separate organsPrincipal Investigator
- Principal Investigator
  
  kuwabara tomoko
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Functional analysis of impairment of neural stem cells under diabetesPrincipal Investigator
- Principal Investigator
  
  Kuwabara Tomoko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Institute of Advanced Industrial Science and Technology
海馬グリア細胞の環境応答機構の解明Principal Investigator
- Principal Investigator
  
  桑原知子
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Molecular mechanisms of mild exercise enhance cognitive function : Developing a novel exercise protocol for the mind
- Principal Investigator
  
  SOYA Hideaki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Sports science
- Research Institution
  University of Tsukuba
Relation between paracrine factors promoting adult neurogenesis and neurological diseasesPrincipal Investigator
- Principal Investigator
  
  KUWABARA Tomoko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  National Institute of Advanced Industrial Science and Technology
ノンコーディングRNAを介した神経新生の分子制御機構の解明Principal Investigator
- Principal Investigator
  
  桑原知子 (藁科知子)
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neuroscience in general
- Research Institution
  National Institute of Advanced Industrial Science and Technology
神経幹細胞からの神経分化を制御する小さなモジュレーターRNAの制御機構Principal Investigator
- Principal Investigator
  
  藁科知子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Advanced Industrial Science and Technology

All 2023 2019 2018 2015 2014 2013 2012 2011 2010 2006 Other

All Journal Article Presentation Book Patent Other

[Book] 視覚でとらえるフォトサイエンス生物図録 DVD-ROM2023
- Author(s)
  嶋田正和、坂井建雄、園池公穀、田村実、中村賢太郎、成川礼、桑原知子
- Total Pages
  320
- Publisher
  数研出版
- ISBN
  9784410281662
- Data Source
  KAKENHI-PROJECT-18K10879
[Journal Article] The regulation of stem cell aging by Wnt signaling.2015
- Author(s)
  Fujimaki S, Wakabayashi T, Takemasa T, Asashima M, Kuwabara T
- Journal Title
  
  Histol Histopathol
  
  Volume: 12 Pages: 1411-1430
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290029
[Journal Article] MicroRNAs and the epigenetics in adult neurogenesis2014
- Author(s)
  Wakabayashi T, Hidaka R, Fujimaki S, Asashima M and Kuwabara T
- Journal Title
  
  Adv Genet
  
  Volume: 1 Pages: 1-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25290029
[Journal Article] Transdisciplinary Approach for Sarcopenia. The effects of exercise on skeletal muscle hypertrophy and satellite cells2014
- Author(s)
  Fujimaki S, Takemasa T, Kuwabara T
- Journal Title
  
  Clin Calcium.
  
  Volume: 24 Pages: 1463-1470
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25290029
[Journal Article] MicroRNAs and the epigenetics in adult neurogenesis2014
- Author(s)
  Wakabayashi T, Hidaka R, Fujimaki S, Asashima M and Kuwabara T
- Journal Title
  
  Adv Genet
  
  Volume: 1 Pages: 1-13
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24111560
[Journal Article] Prospects for regeneration therapy with stem cells2012
- Author(s)
  Tomoko Kuwabara, Makoto Asashima
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 32 Pages: 8-15
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24111560
[Journal Article] Environmental activation of retroelements during adult neurogenesis2012
- Author(s)
  Tomoko Kuwabara
- Journal Title
  
  Environment and Epigenetics
  
  Volume: 1 Pages: 1-1
- Data Source
  KAKENHI-PUBLICLY-24111560
[Journal Article] Olfactory bulb-derived neural stem cells of diabetes therapy2012
- Author(s)
  Kuwabara T and Asashima M
- Journal Title
  
  Aroma Research
  
  Volume: 13 Pages: 31-35
- URL
  http://www.fujisan.co.jp/product/1281680951/b/756256/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700385
[Journal Article] Prospects for regeneration therapy with stem cells2012
- Author(s)
  Kuwabara T and Asashima M
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 32 Pages: 438-445
- URL
  http://jsir.gr.jp/journal/Vol32No1/contents.html
- Data Source
  KAKENHI-PROJECT-22700385
[Journal Article] Active expression of retroelements in neurons differentiated from adult hippocampal neural stem cells2012
- Author(s)
  Antoszczyk S, Terashima K, Warashina M, Asashima M, Kuwabara T
- Journal Title
  
  Neural Stem Cells and Therapy
  
  Volume: 11 Pages: 223-238
- DOI
  10.5772/30105
- ISBN
  9789533079585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700385, KAKENHI-PUBLICLY-24111560
[Journal Article] Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis2011
- Author(s)
  Okamoto M, Inoue K, Iwamura H, Terashima K, Soya H: Asashima M, Kuwabara T
- Journal Title
  
  FASEB J
  
  Volume: 10 Issue: 10 Pages: 3570-3582
- DOI
  10.1096/fj.11-184697
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J01243, KAKENHI-PROJECT-22700385, KAKENHI-PROJECT-23240091
[Journal Article] Active expression of retroelements in neurons differentiated from adult hippocampal neural stem cells2011
- Author(s)
  桑原知子, 他
- Journal Title
  
  Neural Stem Cells (Intech)
  
  Volume: 1 Pages: 1-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700385
[Journal Article] Noncoding RNAs in the mammalian central nervous system2006
- Author(s)
  Cao X, Yeo G, Muotri AR, Kuwabara T, Gage FH
- Journal Title
  
  Annu Rev Neurosci. 29
  
  Pages: 77-103
- Data Source
  KAKENHI-PROJECT-18650090
[Journal Article] A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells2006
- Author(s)
  Warashina M, Min KH, Kuwabara, T, Huynh A, Gage FH, Schultz PG, Ding S.
- Journal Title
  
  Angew Chem Int Ed Engl. 45
  
  Pages: 591-593
- Data Source
  KAKENHI-PROJECT-17024070
[Journal Article] A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells.2006
- Author(s)
  Warashina M, Min KH, Kuwabara T, Huynh A, Gage FH, Schultz PG, Ding S
- Journal Title
  
  Angew Chem Int Ed Engl. 45・4
  
  Pages: 591-593
- Data Source
  KAKENHI-PROJECT-18650090
[Journal Article] Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation.2006
- Author(s)
  Barkho BZ, Song H, Aimone JB, Smrt RD, Kuwabara T, Nakashima K, Gage FH, Zhao X
- Journal Title
  
  Stem Cells Dev. 15・3
  
  Pages: 407-421
- Data Source
  KAKENHI-PROJECT-18650090
[Journal Article] Non-coding RNAs in the Mammalian Central Nervas System,
- Author(s)
  Cao, X., Yeo, G., Muotri, A., Kuwabara, T., Gage FH
- Journal Title
  
  Annu Rev Neurosci. (in press)
- Data Source
  KAKENHI-PROJECT-17024070
[Journal Article] Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation.
- Author(s)
  Barkho, BZ., Song, H., Aimone, JB., Smrt, RD., Kuwabara, T.et al.
- Journal Title
  
  Stem Cell and Development (in press)
- Data Source
  KAKENHI-PROJECT-17024070
[Patent] 海馬または嗅球由来の成体神経幹細胞を用いた神経・　　　　　　精神疾患および糖尿病のモニタリング方法2013
- Inventor(s)
  桑原知子
- Industrial Property Rights Holder
  桑原知子
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-060512
- Filing Date
  2013-03-25
- Data Source
  KAKENHI-PUBLICLY-24111560
[Presentation] The regulation of stem cell aging by Wnt signaling.2023
- Author(s)
  桑原知子
- Organizer
  神経科学合同研究会
- Data Source
  KAKENHI-PROJECT-18K10879
[Presentation] The regulation of neural stem cell in the hippocampus and the olfactory bulb under the diabetes2019
- Author(s)
  桑原知子
- Organizer
  The Adult Neurogenesis Conference
- Data Source
  KAKENHI-PROJECT-18K10879
[Presentation] 疾患や加齢による成体幹細胞の制御機構変化2019
- Author(s)
  桑原知子、若林玲美、藤巻慎、武政徹
- Organizer
  産総研・産技連LS-BT合同研究発表会
- Data Source
  KAKENHI-PROJECT-18K10879
[Presentation] The regulation of neural stem cell in the hippocampus and the olfactory bulb under the diabetes2018
- Author(s)
  桑原知子
- Organizer
  The Adult Neurogenesis Conference
- Data Source
  KAKENHI-PROJECT-18K10879
[Presentation] Regulatory mechanism of hippocampal astroglia secreting Wnt3 in adult neurogenesis2013
- Author(s)
  Masanao MACHIDA, Ryo HIDAKA, Shin FUJIMAKI, Makoto ASASHIMA, Tomoko KUWABARA
- Organizer
  第12回産総研・産技連 LS-BT 合同研究発表会
- Place of Presentation
  茨城県つくば市
- Year and Date
  2013-02-05
- Data Source
  KAKENHI-PUBLICLY-24111560
[Presentation] Environmental activation of retroelements during adult neurogenesis, Environment and Epigenetics2012
- Author(s)
  Kuwabara T
- Organizer
  The 8th Okazaki Biology Conference
- Place of Presentation
  National Institute for Basic Biology, NIBB(愛知県)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22700385
[Presentation] Regulatory mechanism of hippocampal astroglia secreting Wnt3 in adulut neurogenesis2012
- Author(s)
  Masanao MACHIDA, Ryo HIDAKA, Shin FUJIMAKI, Makoto ASASHIMA, Tomoko KUWABARA
- Organizer
  脳疾患関連３領域合同国際シンポジウム
- Place of Presentation
  仙台市
- Year and Date
  2012-07-25
- Data Source
  KAKENHI-PUBLICLY-24111560
[Presentation] Extrinsic Cues and Intracellular Epigenetic Regulations that Control Adult Neurogenesis2011
- Author(s)
  Kuwabara T
- Organizer
  日本神経科学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-09-04
- Data Source
  KAKENHI-PROJECT-22700385
[Presentation] Extrinsic Cues and Intracellular Epigenetic Regulations that Control Adult Neurogenesis2011
- Author(s)
  Kuwabara T.
- Organizer
  日本神経科学会
- Place of Presentation
  パシフィコ横浜(神奈川県)(招待講演)
- Year and Date
  2011-09-04
- Data Source
  KAKENHI-PROJECT-22700385
[Presentation] 自家幹細胞を用いた糖尿病の再生医療技術の開発2011
- Author(s)
  Kuwabara T.
- Organizer
  LS-BT合同研究発表会
- Place of Presentation
  産業技術総合研究所(茨城県)(招待講演)
- Year and Date
  2011-01-31
- Data Source
  KAKENHI-PROJECT-22700385
[Presentation] 自家幹細胞を用いた糖尿病の再生医療技術の開発2011
- Author(s)
  Kuwabara T
- Organizer
  LS-BT合同研究発表会
- Place of Presentation
  産業技術総合研究所(茨城県)
- Year and Date
  2011-01-31
- Data Source
  KAKENHI-PROJECT-22700385
[Presentation] アストロサイト細胞が産生する外的因子の成体神経新生を調節する機構Astrocytes secreting paracrine factors control hippocampal aging and neurogenesis2011
- Author(s)
  寺島和行, 岡本正洋, 井上恒志郎, 岩村弘基, 征矢英昭, 浅島誠, 桑原知子
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜神奈川
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-23240091
[Presentation] 海馬の神経新生とレトロトランスポゾン-環境への依存性と疾患との関わり-2011
- Author(s)
  Kuwabara T.
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22700385
[Presentation] 海馬の神経新生とレトロトランスポゾン-環境への依存性と疾患との関わり-2011
- Author(s)
  Kuwabara T
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22700385
[Presentation] 環境がレトロエレメントを介した成体の神経新生に与える影響2010
- Author(s)
  桑原知子
- Organizer
  日本遺伝学会
- Place of Presentation
  札幌、北海道大学
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-22700385
[Presentation] 環境がレトロエレメントを介した成体の神経新生に与える影響2010
- Author(s)
  Kuwabara T
- Organizer
  日本遺伝学会
- Place of Presentation
  北海道大学(札幌)
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-22700385
[Presentation] 過負荷刺激が骨格筋衛星細胞の分化制御に及ぼす影響
- Author(s)
  藤巻慎、町田正直、日高亮、桑原知子、武政徹
- Organizer
  日本運動生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PUBLICLY-24111560
[Presentation] 成体脳由来の神経幹細胞からの神経新生
- Author(s)
  桑原知子
- Organizer
  日本組織細胞化学会総会
- Place of Presentation
  航空会館（東京都）
- Data Source
  KAKENHI-PROJECT-25290029
[Presentation] 成体脳由来の神経幹細胞からの神経新生
- Author(s)
  桑原知子
- Organizer
  日本組織細胞化学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PUBLICLY-24111560
[Presentation] 代償性過負荷に伴う骨格筋衛星細胞の性質の変容
- Author(s)
  藤巻慎、日高亮、町田正直、浅島誠、武政徹、桑原知子
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸国際会議場(神戸市)
- Data Source
  KAKENHI-PROJECT-25290029
[Presentation] 代償性過負荷に伴う骨格筋衛星細胞の性質の変容
- Author(s)
  藤巻慎、日高亮、町田正直、浅島誠、武政徹、桑原知子
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PUBLICLY-24111560
[Presentation] 過負荷刺激が骨格筋衛星細胞の分化制御に及ぼす影響
- Author(s)
  藤巻慎、町田正直、日高亮、桑原知子、武政徹
- Organizer
  日本運動生理学会大会
- Place of Presentation
  東京国際大学（東京都）
- Data Source
  KAKENHI-PROJECT-25290029
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1. SOYA Hideaki (50221346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. KAWATO Suguru (50169736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. LIU Yu-Fan (90599680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TOHRU Takemasa (50236501)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 藤巻慎 (10795678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

kuwabara Tomoko 桑原 知子

kuwabara tomoko 桑原 知子

KUWABARA Tomoko 桑原 知子

桑原 知子 クラバラ トモコ

藁科 知子 ワラシナ トモコ

Research Projects

Research Products

Co-Researchers

Effects of physical exercise on the regulation of adult stem cells existed independently in separate organsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of impairment of neural stem cells under diabetesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

海馬グリア細胞の環境応答機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of mild exercise enhance cognitive function : Developing a novel exercise protocol for the mind

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Relation between paracrine factors promoting adult neurogenesis and neurological diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ノンコーディングRNAを介した神経新生の分子制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経幹細胞からの神経分化を制御する小さなモジュレーターRNAの制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 視覚でとらえるフォトサイエンス生物図録 DVD-ROM2023

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] The regulation of stem cell aging by Wnt signaling.2015

Author(s)

Journal Title

Data Source

[Journal Article] MicroRNAs and the epigenetics in adult neurogenesis2014

Author(s)

Journal Title

Data Source

[Journal Article] Transdisciplinary Approach for Sarcopenia. The effects of exercise on skeletal muscle hypertrophy and satellite cells2014

Author(s)

Journal Title

Data Source

[Journal Article] MicroRNAs and the epigenetics in adult neurogenesis2014

Author(s)

Journal Title

Data Source

[Journal Article] Prospects for regeneration therapy with stem cells2012

Author(s)

Journal Title

Data Source

[Journal Article] Environmental activation of retroelements during adult neurogenesis2012

Author(s)

Journal Title

Data Source

kuwabara Tomoko 桑原知子

kuwabara tomoko 桑原知子

KUWABARA Tomoko 桑原知子

桑原知子クラバラトモコ

藁科知子ワラシナトモコ

[Patent] 海馬または嗅球由来の成体神経幹細胞を用いた神経・　　　　　　精神疾患および糖尿病のモニタリング方法2013