TAKAI Daiya 高井大哉

Researcher Number	90361493
Other IDs
Affiliation (based on the past Project Information) *help	2005 – 2013: 東京大学, 医学部附属病院, 講師 2008: 東京大学, 医学部・附属病院, 講師 2004: 東京大学, 医学部附属病院, 特任講師(病院)
Review Section/Research Field	Principal Investigator Laboratory medicine / Respiratory organ internal medicine / Biological Sciences Except Principal Investigator Thoracic surgery / Respiratory organ internal medicine
Keywords	Principal Investigator 腫瘍検査学 / 肺がん / siRNA / 発現制御 / マイクロＲＮＡ / ３'非翻訳領域 / 個別化医療 / ＲＥＴ / ＦＥＲ / チロシンキナーゼ … More / 転写制御 / 原発性肺癌 / マイクロRNA / 疾患動物モデル / 間質性肺炎 / DNAメチル化 / ゲノム / がん … More Except Principal Investigator 遺伝子 / 外科 / ゲノム / 癌 / 呼吸器外科学 / 生理活性ペプチド / 抗菌ペプチド / 脂質性メディエーター / ノックアウトマウス / 転写コアクチベーター / 転写因子 / 脂質メディエーター / 肺炎症 / 呼吸器感染症 / 肺線維症 / 非閉塞性肺疾患癌 Less

Chromosomal instability and Clinico-pathologial feature in Lung CancerPrincipal Investigator
- Principal Investigator
  
  TAKAI Daiya
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  The University of Tokyo
Identification of target for next generation tyrosine kinase inhibitor and clinical markers for sensitive patientsPrincipal Investigator
- Principal Investigator
  
  TAKAI Daiya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  The University of Tokyo
肺癌におけるマイクロRNA発現の異常と転写制御崩壊の基礎・臨床的検討Principal Investigator
- Principal Investigator
  
  高井大哉
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
The investigation of molecular mechanisms underlying refractory respiratory diseases and exploration of novel therapeutic targets
- Principal Investigator
  
  NAGASE Takahide
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo
Construction of the system for lung cancer treatment based onmethylation profile and EGFR mutation
- Principal Investigator
  
  MURAKAWA Tomohiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  The University of Tokyo
ヒトがん細胞におけるゲノムの異常なメチル化の機構の解明Principal Investigator
- Principal Investigator
  
  高井大哉
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
ヘアピンsiRNAベクターを用いた炎症性肺疾患治療の標的分子の同定Principal Investigator
- Principal Investigator
  
  高井大哉
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokyo

All 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Other

[Book] 統計物理化学から学ぶバイオインフォマティクス2004
- Author(s)
  Peter Clote, Rolf Backofen著, 高木利久監訳, 小野尚孝, 高井大哉, 高井貴子訳
- Total Pages
  267
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-16021214
[Book] 統計物理化学から学ぶバイオインフォマティクス2004
- Author(s)
  Peter Clote, Rolf Backofen著, 高木利久監訳, 小野尚孝, 高井大哉, 高井貴子訳
- Total Pages
  267
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-16689018
[Journal Article] Combined Large Cell Neuroendocrine Carcinoma and Adenocarcinoma with Epidermal Growth Factor Receptor Mutation in a Female Patient Who Never Smoked2014
- Author(s)
  Yoshida Y, Ota S, Murakawa T, Takai D
- Journal Title
  
  ATCS
  
  Volume: 20 Issue: Supplement Pages: 582-584
- DOI
  10.5761/atcs.cr.12.02217
- NAID
  130003377861
- ISSN
  1341-1098, 2186-1005
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390147, KAKENHI-PROJECT-24659267
[Journal Article] Detection of novel paraja ring finger 2-fer tyrosine kinase mRNA chimeras is associated with poor postoperative prognosis in non-small cell lung cancer2013
- Author(s)
  Kawakami M, Ishikawa R, Amano Y, Sunohara M, Watanabe K, Ohishi N, Yatomi Y, Nakajima J, Fukayama M, Nagase T, Takai D
- Journal Title
  
  Cancer Sci
  
  Volume: 104(11) Pages: 1447-1454
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] High-grade lung adenocarcinoma with fetal-lung-like morphology - Clinicopathological, immunohistochemical, and molecular analyses of 17 cases2013
- Author(s)
  Morita S, Yoshida A, Goto A, Ota S, Tsuta K, Yokozawa K, Asamura H, Nakajima J, Takai D, Mori M, Oka T, Tamaru J, Itoyama S, Furuta K, Fukayama M, Tsuda H
- Journal Title
  
  American J of Surg. Pathology
  
  Volume: 37(6) Pages: 924-932
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Disruption of the expression and function of microRNAs in lung cancer as a result of epigenetic changes.2013
- Author(s)
  Watanabe K, Takai D.
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 4 Pages: 275-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] Growth-associated hyperphosphatemia in young recipients accelerates aortic allograft calcification in a rat model2013
- Author(s)
  Yamauchi H, Motomura N, Chung UI, Sata M, Takai D, Saito A, Ono M, Takamoto S
- Journal Title
  
  J Thorac Cardiovasc Surg
  
  Volume: 145(2) Pages: 522-530
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] FER overexpression is associated with poor postoperative prognosis and cancer-cell survival in non-small cell lung cancer.2013
- Author(s)
  Kawakami M, Morita S, Sunohara M, Amano Y, Ishikawa R, Watanabe K, Hamano E, Ohishi N, Nakajima J, Yatomi Y, Nagase T, Fukayama M, Takai D.
- Journal Title
  
  International Journal of Clinical & Experimental Pathology
  
  Volume: 6 Pages: 598-612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] High-grade lung adenocarcinoma with fetal-lung-like morphology ? Clinicopathological, immunohistochemical, and molecular analyses of 17 cases2013
- Author(s)
  Morita S, Yoshida A, Goto A, Ota S, Tsuta K, Yokozawa K, Asamura H, Nakajima J, Takai D, Mori M, Oka T, Tamaru J, Itoyama S, Furuta K, Fukayama M, Tsuda H
- Journal Title
  
  American Journal of Surgical Pathology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] Growth-associated hyperphosphatemia in young recipients accelerates aortic allograft calcification in a rat model2013
- Author(s)
  Yamauchi H, Motomura N, Chung UI, Sata M, Takai D, Saito A, Ono M, Takamoto S.
- Journal Title
  
  J Thorac Car diovasc Surg
  
  Volume: 145(2) Pages: 522-530
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] A pilot study of salvage irinotecan monotherapy for advanced biliary tract cancer2013
- Author(s)
  Sasaki T, Isayama H, Nakai Y, Takahara N, Satoh Y, Takai D, Kogure H, Yamamoto N, Hirano K, Tada M, Yatomi Y, Koike K.
- Journal Title
  
  Anticancer Res
  
  Volume: 33(6) Pages: 2619-2622
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] Combined Large Cell Neuroendocrine Carcinoma and Adenocarcinoma with Epidermal Growth Factor Receptor Mutation in a Female Patient Who Never Smoked2013
- Author(s)
  Yoshida Y, Ota S, Murakawa T, Takai D, Nakajima J
- Journal Title
  
  Ann Thorac Cardiovasc Surg
- NAID
  130003377861
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Combined Large Cell Neuroendocrine Carcinoma and Adenocarcinoma with Epidermal Growth Factor Receptor Mutation in a Female Patient Who Never Smoked.2013
- Author(s)
  Yoshida Y, Ota S, Murakawa T, Takai D, Nakajima J.
- Journal Title
  
  Annals of Thoracic and Cardiovascular Surgery
  
  Volume: Epub ahead
- NAID
  130003377861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] A pilot study of salvage irinotecan monotherapy for advanced biliary tract cancer.2013
- Author(s)
  Sasaki T, Isayama H, Nakai Y, Takahara N, Satoh Y, Takai D, Kogure H, Yamamoto N, Hirano K, Tada M, Yatomi Y, Koike K.
- Journal Title
  
  Anticancer Research
  
  Volume: 33 Pages: 2619-2622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Combined Large Cell Neuroendocrine Carcinoma and Adenocarcinoma with Epidermal Growth Factor Receptor Mutation in a Female Patient Who Never Smoked.2013
- Author(s)
  Yoshida Y, Ota S, Murakawa T, Takai D, Nakajima J.
- Journal Title
  
  Annals of Thoracic and Cardiovascular Surgery
  
  Volume: Epub ahead
- NAID
  130003377861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] FER overexpression is associated with poor postoperative prognosis and cancer-cell survival in non-small cell lung cancer2013
- Author(s)
  Kawakami M, Morita S, Sunohara M, Amano Y, Ishikawa R, Watanabe K, Hamano E, Ohishi N, Nakajima J, Yatomi Y, Nagase T, Fukayama M, Takai D.
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 6(4) Pages: 598-612
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] Uridine diphosphate glucuronosyl transferase 1 family polypeptide A1 gene (UGT1A1) polymorphisms are associated with toxicity and efficacy in irinotecan monotherapy for refractory pancreatic cancer2013
- Author(s)
  Takahara N, Nakai Y, Isayama H, Sasaki T, Satoh Y, Takai D, Hamada T, Uchino R, Mizuno S, Miyabayashi K, Mohri D, Kawakubo K, Kogure H, Yamamoto N, Sasahira N, Hirano K, Ijichi H, Tada M, Yatomi Y, Koike K
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 71(1) Pages: 85-92
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Disruption of the expression and function of microRNAs in lung cancer as a result of epigenetic changes.2013
- Author(s)
  Watanabe K, Takai D.
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 4 Pages: 275-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Growth-associated hyperphosphatemia in young recipients accelerates aortic allograft calcification in a rat model.2013
- Author(s)
  Yamauchi Haruo
- Journal Title
  
  The Journal of Thoracic and Cardiovascular Surgery
  
  Volume: 145 Issue: 2 Pages: 522-530
- DOI
  10.1016/j.jtcvs.2012.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390159, KAKENHI-PROJECT-23390147, KAKENHI-PROJECT-23592028, KAKENHI-PROJECT-24659267, KAKENHI-PROJECT-24659392, KAKENHI-PROJECT-25670390
[Journal Article] FER overexpression is associated with poor postoperative prognosis and cancer-cell survival in nonsmall cell lung cancer2013
- Author(s)
  Masanori Kawakami, Shigeki Morita, Mitsuhiro Sunohara, Yosuke Amano, Rie Ishikawa, Kousuke Watanabe, Emi Hamano, Nobuya Ohishi,Yutaka Yatomi, Takahide Nagase, Masashi Fukayama, Daiya Takai
- Journal Title
  
  International Journal of Clinical and Experimental Pathology
  
  Volume: 6 Pages: 598-612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] Disruption of the expression and function of microRNAs in lung cancer as a result of epigenetic changes2013
- Author(s)
  Watanabe K & Takai D.
- Journal Title
  
  Frontier s in Genetics
  
  Volume: 4 Pages: 275-275
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] FER overexpression is associated with poor postoperative prognosis and cancer-cell survival in non-small cell lung cancer.2013
- Author(s)
  Kawakami M, Morita S, Sunohara M, Amano Y, Ishikawa R, Watanabe K, Hamano E, Ohishi N, Nakajima J, Yatomi Y, Nagase T, Fukayama M, Takai D.
- Journal Title
  
  International Journal of Clinical & Experimental Pathology
  
  Volume: 6 Pages: 598-612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] High-grade lung adenocarcinoma with fetal-lung-like morphology–Clinicopathological, immunohistochemical, and molecular analyses of 17 cases2013
- Author(s)
  Morita S, Yoshida A, Goto A, Ota S, Tsuta K, Yokozawa K, Asamura H, Nakajima J, Takai D, Mori M, Oka T, Tamaru J, Itoyama S, Furuta K, Fukayama M, Tsuda H.
- Journal Title
  
  Amer ican J of Sur g. Pathology
  
  Volume: 37(6) Pages: 924-932
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] Detection of novel paraja ring finger 2-fer tyrosine kinase mRNA chimeras is associated with poor postoperative prognosis in non-small cell lung cancer2013
- Author(s)
  Kawakami M, Ishikawa R, Amano Y, Sunohara M, Watanabe K, Ohishi N, Yatomi Y, Nakajima J, Fukayama M, Nagase T, Takai D.
- Journal Title
  
  Cancer Sci
  
  Volume: 104(11) Pages: 1447-1454
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] FER overexpression is associated with poor postoperative prognosis and cancer-cell survival in non-small cell lung cancer2013
- Author(s)
  Kawakami M, Morita S, Sunohara M, Amano Y, Ishikawa R, Watanabe K, Hamano E, Ohishi N, Nakajima J, Yatomi Y, Nagase T, Fukayama M, Takai D
- Journal Title
  
  International Journal of Clinical and Experimental Pathology
  
  Volume: 6 Pages: 598-612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Uridine diphosphate glucuronosyl transferase 1 family polypeptide A1 gene (UGT1A1) polymorphisms are associated with toxicity and efficacy in irinotecan monotherapy for refractory pancreatic cancer2013
- Author(s)
  Takahara N, Nakai Y, Isayama H, Sasaki T, Satoh Y, Takai D, Hamada T, Uchino R, Mizuno S, Miyabayashi K, Mohri D, Kawakubo K, Kogure H, Yamamoto N, Sasahira N, Hirano K, Ijichi H, Tada M, Yatomi Y, Koike K.
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 71(1) Pages: 85-92
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] Successful Treatment of Mediastinal Unicentric Castleman's Disease Using Video-Assisted Thoracoscopic Surgery with Preoperative Embolization2013
- Author(s)
  Amano Y, Takai D, Ohishi N, Shinozaki-Ushiku A, Fukayama M, Akahane M, Nakajima J, Nagase T.
- Journal Title
  
  Case Rep Med
  
  Pages: 354507-354507
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] Successful Treatment of Mediastinal Unicentric Castleman's Disease Using Video-Assisted Thoracoscopic Surgery with Preoperative Embolization.2013
- Author(s)
  Amano Y, Takai D, Ohishi N, Shinozaki-Ushiku A, Fukayama M, Akahane M, Nakajima J, Nagase T.
- Journal Title
  
  Case Reports in Medicine
  
  Volume: 2013 Pages: 354507-354507
- DOI
  10.1155/2013/354507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] Successful Treatment of Mediastinal Unicentric Castleman's Disease Using Video-Assisted Thoracoscopic Surgery with Preoperative Embolization.2013
- Author(s)
  Amano Y, Takai D, Ohishi N, Shinozaki-Ushiku A, Fukayama M, Akahane M, Nakajima J, Nagase T.
- Journal Title
  
  Case Reports in Medicine
  
  Volume: 2013 Pages: 354507-354507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] A pilot study of salvage irinotecan monotherapy for advanced biliary tract cancer2013
- Author(s)
  Sasaki T, Isayama H, Nakai Y, Takahara N, Satoh Y, Takai D, Kogure H, Yamamoto N, Hirano K, Tada M, Yatomi Y, Koike K
- Journal Title
  
  Anticancer Res
  
  Volume: 33(6) Pages: 2619-2622
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Detection of novel paraja ring finger 2-fer tyrosine kinase mRNA chimeras is associated with poor postoperative prognosis in non-small cell lung cancer.2013
- Author(s)
  Kawakami M, Ishikawa R, Amano Y, Sunohara M, Watanabe K, Ohishi N, Yatomi Y, Nakajima J, Fukayama M, Nagase T, Takai D.
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Issue: 11 Pages: 1447-1454
- DOI
  10.1111/cas.12250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249045, KAKENHI-PROJECT-23390147, KAKENHI-PROJECT-24659267, KAKENHI-PROJECT-25860402
[Journal Article] A pilot study of salvage irinotecan monotherapy for advanced biliary tract cancer.2013
- Author(s)
  Sasaki T, Isayama H, Nakai Y, Takahara N, Satoh Y, Takai D, Kogure H, Yamamoto N, Hirano K, Tada M, Yatomi Y, Koike K.
- Journal Title
  
  Anticancer Research
  
  Volume: 33 Pages: 2619-2622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] Combined Large Cell Neuroendocrine Carcinoma and Adenocarcinoma with Epidermal Growth Factor Receptor Mutation in a Female Patient Who Never Smoked2013
- Author(s)
  Yoshida Y, Ota S, Murakawa T, Takai D, Nakajima J.
- Journal Title
  
  Ann Thorac Cardiovasc Sur g
  
  Volume: (Epub ahead)
- NAID
  130003377861
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] High-grade lung adenocarcinoma with fetal-lung-like morphology ? Clinicopathological, immunohistochemical, and molecular analyses of 17 cases2013
- Author(s)
  Morita S, Yoshida A, Goto A, Ota S, Tsuta K, Yokozawa K, Asamura H, Nakajima J, Takai D, Mori M, Oka T, Tamaru J, Itoyama S, Furuta K, Fukayama M, Tsuda H
- Journal Title
  
  American Journal of Surgical Pathology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Successful Treatment of Mediastinal Unicentric Castleman's Disease Using Video-Assisted Thoracoscopic Surgery with Preoperative Embolization2013
- Author(s)
  Amano Y, Takai D, Ohishi N, Shinozaki-Ushiku A, Fukayama M, Akahane M, Nakajima J, Nagase T
- Journal Title
  
  Case Rep Med
  
  Volume: 2013 Pages: 354507-354507
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] FER overexpression is associated with poor postoperative prognosis and cancer-cell survival in non-small cell lung cancer2013
- Author(s)
  Kawakami M, Morita S, Sunohara M, Amano Y, Ishikawa R, Watanabe K, Hamano E, Ohishi N, Nakajima J, Yatomi Y, Nagase T, Fukayama M, Takai D
- Journal Title
  
  Int J Clin Exp Pathol
  
  Volume: 6(4) Pages: 598-612
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Disruption of the expression and function of microRNAs in lung cancer as a result of epigenetic changes2013
- Author(s)
  Watanabe K & Takai D
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 4 Pages: 275-275
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] High-grade Lung Adenocarcinoma With Fetal Lung-like Morphology: Clinicopathologic, Immunohistochemical, and Molecular Analyses of 17 Cases2013
- Author(s)
  Morita S, Yoshida A, Goto A, Ota S, Tsuta K, Yokozawa K, Asamura H, Nakajima J, Takai D, Mori M, Oka T, Tamaru J, Itoyama S, Furuta K, Fukayama M, Tsuda H.
- Journal Title
  
  Am J Surg Pathol
  
  Volume: 37(6) Issue: 6 Pages: 924-932
- DOI
  10.1097/pas.0b013e31827e1e83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590307, KAKENHI-PROJECT-23390147, KAKENHI-PROJECT-24659267, KAKENHI-PROJECT-24659625, KAKENHI-PROJECT-25290051, KAKENHI-PROJECT-25460431
[Journal Article] Uridine diphosphate glucuronosyl transferase 1 family polypeptide A1 gene (UGT1A1) polymorphisms are associated with toxicity and efficacy in irinotecan monotherapy for refractory pancreatic cancer2013
- Author(s)
  Takahara N, Nakai Y, Isayama H, Sasaki T, Satoh Y, Takai D, Miyabayashi K, Mohri D, Kawakubo K, Kogure H, Yamamoto N, Sasahira N, Hirano K, Ijichi H, Tada M, Yatomi Y, Koike K
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
  
  Volume: 71 Issue: 1 Pages: 85-92
- DOI
  10.1007/s00280-012-1981-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390147, KAKENHI-PROJECT-24591005, KAKENHI-PROJECT-24659267
[Journal Article] Genome structure-based screening identifiedepigenetically silenced microRNA associated with invasiveness in non-small-cell lung cancer.2012
- Author(s)
  Watanabe K, Goto A, Takai D.
- Journal Title
  
  Int J Cancer.
  
  Volume: 130 Issue: 11 Pages: 2580-2590
- DOI
  10.1002/ijc.26254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300336, KAKENHI-PROJECT-22590307, KAKENHI-PROJECT-22790749, KAKENHI-PROJECT-23390147, KAKENHI-PROJECT-24659267
[Journal Article] Pulmonary Venous Invasion, Determined by Chest Computed Tomographic Scan, as a Potential Early Indicator of Zygomycosis Infection : A Case Series2012
- Author(s)
  Kitagawa H, Watanabe K, Kage H, Inoh S, Goto A, Fukayama M, Nagase T, Ohishi N, Takai D.
- Journal Title
  
  J Thorac Imaging
  
  Volume: 27(4)
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] Pulmonary Venous Invasion, Determined by Chest Computed Tomographic Scan, as a Potential Early Indicator of Zygomycosis Infection : A Case Series2012
- Author(s)
  Kitagawa H, Watanabe K, Kage H, Inoh S, Goto A, Fukayama M, Nagase T, Ohishi N, Takai D
- Journal Title
  
  J Thorac Imaging
  
  Volume: 27(4)
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Pulmonary Venous Invasion, Determined by Chest Computed Tomographic Scan, as a Potential Early Indicator of Zygomycosis Infection: A Case Series2012
- Author(s)
  Kitagawa H, Watanabe K, Kage H, Inoh S, Goto A, Fukayama M, Nagase T, Ohishi N, Takai D
- Journal Title
  
  J Thorac Imaging
  
  Volume: 27 Issue: 4 Pages: W97-W99
- DOI
  10.1097/rti.0b013e3182282d17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590307, KAKENHI-PROJECT-23390147, KAKENHI-PROJECT-24659267
[Journal Article] Analysis for the combination expression of CK20, FABP1 and MUC2 is sensitive for the prediction of peritoneal recurrence in gastric cancer2012
- Author(s)
  Satoh Y, Mori K, Kitano K, Kitayama J, Yokota H, Sasaki H, Uozaki H, Fukayama M, Seto Y, Nagawa H, Yatomi Y, Takai D
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 42(2) Pages: 148-152
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Genome structure-based screening identified epigenetically silenced microRNA associated with invasiveness in non-small-cell lung cancer2012
- Author(s)
  Watanabe K, Emoto N, Hamano E, Sunohara M, Kawakami M, Kage H, Kitano K, Nakajima J, Goto A, Fukayama M, Nagase T, Yatomi Y, Ohishi N, Takai D.
- Journal Title
  
  Int J Cancer
  
  Volume: 130(11) Pages: 2580-2590
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] Genome structure-based screening identified epigenetically silenced microRNA associated with invasiveness in non-small-cell lung cancer2012
- Author(s)
  Watanabe K, Emoto N, Hamano E, Sunohara M, Kawakami M, Kage H, Kitano K, Nakajima J, Goto A, Fukayama M, Nagase T, Yatomi Y, Ohishi N, Takai D
- Journal Title
  
  Int J Cancer
  
  Volume: 130(11) Pages: 2580-2590
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Analysis for the combination expression of CK20, FABP1 and MUC2 is sensitive for the prediction of peritoneal recurrence in gastric cancer2012
- Author(s)
  Satoh Y, Takai D, et al.
- Journal Title
  
  Jpn J Clin Oncol.
  
  Volume: 42 Issue: 2 Pages: 148-152
- DOI
  10.1093/jjco/hyr204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Analysis for the combination expression of CK20, FABP1 and MUC2 is sensitive for the prediction of peritoneal recurrence in gastric cancer2012
- Author(s)
  Satoh Y, Mori K, Kitano K, Kitayama J, Yokota H, Sasaki H, Uozaki H, Fukayama M, Seto Y, Nagawa H, Yatomi Y, Takai D.
- Journal Title
  
  J pn J Clin Oncol
  
  Volume: 42(2) Pages: 148-152
- Data Source
  KAKENHI-PROJECT-24659267
[Journal Article] Polymerase reaction without primers throughout for the reconstruction of full-length cDNA from products of rapid amplification of cDNA ends (RACE)2011
- Author(s)
  Sunohara M, Kawakami M, Kage H, Watanabe K, Emoto N, Nagase T, Ohishi N, Takai D
- Journal Title
  
  Biotechnol Lett
  
  Volume: 33(7) Pages: 1301-1307
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] CpG island methylation of microRNAs is associated with tumor size and recurrence of non-small-cell lung cancer2011
- Author(s)
  Kitano K, Watanabe K, Emoto N, Kage H, Hamano E, Nagase T, Sano A, Murakawa T, Nakajima J, Goto A, Fukayama M, Yatomi Y, Ohishi N, Takai D
- Journal Title
  
  Cancer Sci
  
  Volume: 102(12) Pages: 2126-2131
- NAID
  10030245653
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Polymerase reaction without primers throughout for the reconstruction of full-length cDNA from products of rapid amplification of cDNA ends (RACE)2011
- Author(s)
  Sunohara M, Takai D, et al.
- Journal Title
  
  Biotechnol Lett.
  
  Volume: 33 Issue: 7 Pages: 1301-1307
- DOI
  10.1007/s10529-011-0580-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Suppression of Tgf・1 in lung alveolar epithelium-derived cells using adeno-associated virus type 2/5 vectors to carry short hairpin RNA2011
- Author(s)
  Kage H, Sugimoto K, Sano A, Kitagawa H, Nagase T, Ohishi N, Takai D
- Journal Title
  
  Experimental Lung Research
  
  Volume: 37(3) Pages: 175-185
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] Suppression of transforming growth factor β1 in lung alveolar epithelium-derived cells using adeno-associated virus type 2/5 vectors to carry short hairpin RNA2011
- Author(s)
  Kage H, Takai D, et al.
- Journal Title
  
  Exp Lung Res.
  
  Volume: 37 Issue: 3 Pages: 175-185
- DOI
  10.3109/01902148.2010.529985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390147
[Journal Article] CpG island methylation of microRNAs is associated with tumor size and recurrence of non-small-cell lung cancer2011
- Author(s)
  Kitano K, Watanabe K, Emoto N, Kage H, Hamano E, Nagase T, Sano A, Murakawa T, Nakajima J, Goto A, Fukayama M, Yatomi Y, Ohishi N, Takai D.
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 12 Pages: 2126-2131
- DOI
  10.1111/j.1349-7006.2011.02101.x
- NAID
  10030245653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590307, KAKENHI-PROJECT-22591560, KAKENHI-PROJECT-22790749, KAKENHI-PROJECT-23390147
[Journal Article] 血清中のDNAのメチル化を用いた肺癌化学療法感受性予測2010
- Author(s)
  高井大哉
- Journal Title
  
  癌と化学療法 37
  
  Pages: 189-193
- Data Source
  KAKENHI-PROJECT-20659129
[Journal Article] Identification of GOS2 as a gene frequently methylated in squamous lung cancer by combination of in silico and experimental approaches.2010
- Author(s)
  Kusakabe M, Kutomi T, Watanabe K, Emoto N, Aki N, Kage H, Hamano E, Kitagawa H, Nagase T, Sano A, Yoshida Y, Fukami T, Murakawa T, Nakajima J, Takamoto S, Ota S, Fukayama M, Yatomi Y, Ohishi N, Takai D
- Journal Title
  
  Int J Cancer 15 : 126
  
  Pages: 1895-1902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] 肺癌のエピジェネティクス研究の進歩2009
- Author(s)
  高井大哉
- Journal Title
  
  日本臨床 67
  
  Pages: 2387-96
- Data Source
  KAKENHI-PROJECT-20659129
[Journal Article] Impact of DNA demethylation of the G0S2 gene on the transcrip tion of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists.2009
- Author(s)
  Kusakabe M, Watanabe K, Emoto N, Aki N, Kage H, Nagase T, Nakajima J, Yatomi Y, Ohishi N, Takai D
- Journal Title
  
  Biochem Biophys Res Commun 390
  
  Pages: 1283-1287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus.2007
- Author(s)
  Sugimoto K, Kage H, Aki N, Sano A, Kitagawa H, Nagase T, Yatomi Y, Ohishi N, Takai D.
- Journal Title
  
  Biochem Biophys Res Commun 359
  
  Pages: 497-502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591614
[Journal Article] The Induction of H3K9 Methylation by PIWIL4 at the p16Ink4a Locus.2007
- Author(s)
  Sugimoto K, Kage H, Aki N, Sano A, Kitagawa H, Nagase T, Yatomi Y, Ohishi N, Takai D
- Journal Title
  
  Biochem Biophys Res Commun 359
  
  Pages: 497-502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] A second-generation profilingsystem for quantitative methylationanalysis of multiple gene promoters : application to lung cancer2007
- Author(s)
  Sano A, Kage H, Sugimoto K, Kitagawa H, Aki N, Goto A, Fukayama M, Nakajima J, akamoto S, Nagase T, Yatomi Y, Ohishi N, Takai D
- Journal Title
  
  Oncogene 26(45)
  
  Pages: 6518-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591614
[Journal Article] A second-generation profiling system for quantitative methylation analysis of multiple gene promoters : application to lung cancer.2007
- Author(s)
  Sano A, Kage H, Sugimoto K, Kitagawa H, Aki N, Goto A, Fukuyama M, Nakajima J, Takamoto S, Nagase T, Yatomi Y, Ohishi N, Takai D
- Journal Title
  
  Oncogene 26
  
  Pages: 6518-6525
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209031
[Journal Article] A second-generation profiling system for quantitative methylation analysis of multiple gene promoters: application to lung cancer.2007
- Author(s)
  Sano A, Kage H, Sugimoto K, Kitagawa H, Aki N, Goto A, Fukayama M, Nakajima J, Takamoto S, Nagase T, Yatomi Y, Ohishi N, Takai D.
- Journal Title
  
  Oncogene 26
  
  Pages: 6518-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591614
[Journal Article] Cryopreservation does not alter the allogenicity and development of vasculopathy in post-transplant rat aortas2006
- Author(s)
  Saito A, Motomura N, Kakimi K, Ono M, Takai D, Sumida S, Takamoto S.
- Journal Title
  
  Cryobiology (Epub ahead of print)
- Data Source
  KAKENHI-PROJECT-16689018
[Journal Article] Cryopreservation does not alter the allogenicity and development of vasculopathy in post-transplant rat aortas.2006
- Author(s)
  Saito A, Motomura N, Kakimi K, Ono M, Takai D, Sumida S, Takamoto S.
- Journal Title
  
  Cryobiology. 52(2)
  
  Pages: 251-260
- Data Source
  KAKENHI-PROJECT-16689018
[Journal Article] Betaine improved restriction digestion.2005
- Author(s)
  Sugimoto K, Makihara T, Saito A, Ohishi N, Nagase T, Takai D.
- Journal Title
  
  Biochemical and Biophysical Research Communications 337(4)
  
  Pages: 1027-1029
- Data Source
  KAKENHI-PROJECT-16689018
[Journal Article] Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome2004
- Author(s)
  Liang G, Lin JC, Wei V, Yoo C, Cheng JC, Nguyen CT, Weisenberger DJ, Egger G, Takai D, Gonzales FA, Jones PA
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 101
  
  Pages: 7357-7362
- Data Source
  KAKENHI-PROJECT-16689018
[Journal Article] Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome2004
- Author(s)
  Liang G, Lin JC, Wei V, Yoo C, Cheng JC, Nguyen CT, Weisenberger DJ, Egger G, Takai D, Gonzales FA, Jones PA
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 101
  
  Pages: 7357-7362
- Data Source
  KAKENHI-PROJECT-16021214
[Journal Article] Origins of bidirectional promoters : computational analyses of intergenic distance in the human genome2004
- Author(s)
  Takai D, Jones PA
- Journal Title
  
  Molecular Biology and Evolution 21
  
  Pages: 463-467
- Data Source
  KAKENHI-PROJECT-16689018
[Journal Article] New therapeutic key for cystic fibrosis : a role for lipoxins2004
- Author(s)
  Takai D, Nagase T, Shimizu T
- Journal Title
  
  Nature Immunology 5
  
  Pages: 357-358
- Data Source
  KAKENHI-PROJECT-16021214
[Journal Article] New therapeutic key for cystic fibrosis : a role for lipoxins2004
- Author(s)
  Takai D, Nagase T, Shimizu T
- Journal Title
  
  Nature Immunology 5
  
  Pages: 357-358
- Data Source
  KAKENHI-PROJECT-16689018
[Journal Article] Origins of bidirectional promoters : computational analyses of intergenic distance in the human genome2004
- Author(s)
  Takai D, Jones PA
- Journal Title
  
  Molecular Biology and Evolution 21
  
  Pages: 463-467
- Data Source
  KAKENHI-PROJECT-16021214
[Journal Article] A second-generation profiling system for quantitative methylation analysis of multiplegene promoters: application to lung cancer
- Author(s)
  Atsushi Sano, Hidenori Kage, Keiki Sugimoto, Hiroshi Kitagawa, Naomi Aki, Akiteru Goto, Masashi Fukayama, Jun Naka jima, Shinichi Takamoto, Takahide Nagase, Yutaka Yatomi, Nobuya Ohishi and Daiya Takai
- Journal Title
  
  Oncogene (In press)
- Data Source
  KAKENHI-PROJECT-16689018
[Journal Article] PIWIL4, a ubiquitous member of the human PIWI family, is involved in epigenetic silencing of p16
- Author(s)
  Keiki Sugimoto, Hidenori Kage, Atsushi Sano, Naomi Aki, Hiroshi Kitagawa, Takahide Nagase, Yutaka Yatomi, Nobuya Ohishi, and Daiya Takai
- Journal Title
  
  In submission
- Data Source
  KAKENHI-PROJECT-16689018
[Presentation] Histone methylation-mediated silencing of mir-139 enhances an aggressive phenotype of non-small cell lung cancer.2014
- Author(s)
  Watanabe K, Sunohara M, Amano Y, Ishikawa R, Ichinose J, Nakajima J, Fukayama M, Yatomi Y, Nagase T, Ohishi N, Takai D
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24659267
[Presentation] Histone methylation-mediated silencing of mir-139 enhances an aggressive phenotype of non-small cell lung cancer2014
- Author(s)
  Watanabe K, Sunohara M, Amano Y, Ishikawa R, Ichinose J, Nakajima J, Fukayama M, Yatomi Y, Nagase T, Ohishi N, Takai D.
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24659267
[Presentation] Loss of PABPN1 and alternative polyadenylation yield poor prognosis in non-small cell lung cancer.2014
- Author(s)
  Ichinose J, Watanabe K, Sano A, Nagase T, Nakajima J, Fukayama M, Yatomi Y, Ohishi N, Takai D
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] Loss of PABPN1 and alternative polyadenylation yield poor prognosis in non-small cell lung cancer.2014
- Author(s)
  Ichinose J, Watanabe K, Sano A, Nagase T, Nakajima J, Fukayama M, Yatomi Y, Ohishi N, Takai D
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24659267
[Presentation] Can lung cancer with overexpression of RET-proto oncogene be a good candidate for vandetanib treatment?2014
- Author(s)
  Sunohara M, Morita S, Kawakami M, Watanabe K, Kage H, Amano Y, Ishikawa R, Fukayama M, Nagase T, Ohishi N, Takai D
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] Histone methylation-mediated silencing of mir-139 enhances an aggressive phenotype of non-small cell lung cancer2014
- Author(s)
  Watanabe K, Sunohara M, Amano Y, Ishikawa R, Ichinose J, Nakajima J, Fukayama M, Yatomi Y, Nagase T, Ohishi N, Takai D
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] Can lung cancer with overexpression of RET-proto oncogene be a good candidate for vandetanib treatment?2014
- Author(s)
  Sunohara M, Morita S, Kawakami M, Watanabe K, Kage H, Amano Y, Ishikawa R, Fukayama M, Nagase T, Ohishi N, Takai D.
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24659267
[Presentation] Loss of PABPN1 and alternative polyadenylation yield poor prognosis in non-small cell lung cancer2014
- Author(s)
  Ichinose J, Watanabe K, Sano A, Nagase T, Nakajima J, Fukayama M, Yatomi Y, Ohishi N, Takai D
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] Can lung cancer with overexpression of RET-proto oncogene be a good candidate for vandetanib treatment ?2014
- Author(s)
  Sunohara M, Morita S, Kawakami M, Watanabe K, Kage H, Amano Y, Ishikawa R, Fukayama M, Nagase T, Ohishi N, Takai D
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24659267
[Presentation] Can lung cancer with overexpression of RET-proto oncogene be a good candidate for vandetanib treatment ?2014
- Author(s)
  Sunohara M, Morita S, Kawakami M, Watanabe K, Kage H, Amano Y, Ishikawa R, Fukayama M, Nagase T, Ohishi N, Takai D
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] Histone methylation-mediated silencing of mir-139 enhances an aggressive phenotype of non-small cell lung cancer.2014
- Author(s)
  Watanabe K, Sunohara M, Amano Y, Ishikawa R, Ichinose J, Nakajima J, Fukayama M, Yatomi Y, Nagase T, Ohishi N, Takai D
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] Loss of PABPN1 and alternative polyadenylation yield poor prognosis in non-small cell lung cancer2014
- Author(s)
  Ichinose J, Watanabe K, Sano A, Nagase T, Nakajima J, Fukayama M, Yatomi Y, Ohishi N, Takai D.
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24659267
[Presentation] Identification of FER as a New Molecular Target in Non-small Cell Lung Cancer2012
- Author(s)
  M. Kawakami, M. Sunohara, Y. Amano, R. Ishikawa, K. Watanabe, E. Hamano, N. Ohishi, T. Nagase, Y. Yatomi, D. Takai
- Organizer
  The 24th EORTC-NCI-AACR Symposium on ‘Molecular Targets and Cancer Therapeutics'
- Place of Presentation
  Dublin, Ireland
- Data Source
  KAKENHI-PROJECT-24659267
[Presentation] Identification of FER as a New Molecular Target in Non-small Cell Lung Cancer2012
- Author(s)
  Kawakami M, Sunohara M, Amano Y, Ishikawa R, Watanabe K, Hamano E, Ohishi N, Nagase T, Yatomi Y, Takai D.
- Organizer
  The 24th EORTC-NCI- AACR Symposium on'Molecular Targets and Cancer Therapeutics'
- Place of Presentation
  Dublin, Island
- Data Source
  KAKENHI-PROJECT-24659267
[Presentation] CpG island methylation of microRNAs is associated with tumor size and the recurrence of non-small cell lung cancer2012
- Author(s)
  Kitano K, Goto A, Fukayama M, Watanabe K, Emoto N, Kage H, Hamano H, Nagase T, Sano A, Murakawa T, Nakajima J, Yatomi Y, Ohishi N, Takai D
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] Identification of FER as a New Molecular Target in Non-small Cell Lung Cancer2012
- Author(s)
  Kawakami M, Sunohara M, Amano Y, Ishikawa R, Watanabe K, Hamano E, Ohishi N, Nagase T, Yatomi Y, Takai D
- Organizer
  The 24th EORTC-NCI-AACR Symposium on ‘Molecular Targets and Cancer Therapeutics'
- Place of Presentation
  Dublin, Ireland
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] Vandetanib Can Overcome the Acquired Resistance to Gefitinib Due to RET Overexpression in Lung Cancer2012
- Author(s)
  Sunohara M, Kawakami K, Watanabe K, Morita S, Kage H, Amano Y , Fukayama M, Nagase T, N. Ohishi N, Takai D.
- Organizer
  The 24th EORTC-NCI-AACR Symposium on'Molecular Targets and Cancer Therapeutics'
- Place of Presentation
  Dublin, Island
- Data Source
  KAKENHI-PROJECT-24659267
[Presentation] Genome structure-based screening identified epigenetically silenced microRNA associated with invasiveness in non-small cell lung cancer2012
- Author(s)
  Watanabe K, Goto A, Fukayama M, Nagase T, Emoto N, Hamano E, Amano Y, Ishikawa R, Sunohara M, Kawakami M, Kitano K, Nakajima J, Yatomi Y, Ohishi N, Takai D
- Organizer
  AACR-IASLC Joint Conference on The Molecular Origins of Lung Cancer
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] Genome sturucture-based screeening identified epigenetically silenced microRNA associated with invasiveness in non-small cell lung cancer2012
- Author(s)
  Watanabe K, Takai D, et al.
- Organizer
  AACR-IASLC Joint Conference on THE MOLECULAR ORIGINS OF LUNG CANCER
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2012-01-10
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] CpG island methylation of microRNAs is associated with tumor size and the recurrence of non-small cell lung cancer2012
- Author(s)
  Kitano K, Takai D, et al.
- Organizer
  AACR-IASLC Joint Conference on THE MOLECULAR ORIGINS OF LUNG CANCER
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2012-01-09
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] Vandetanib Can Overcome the Aquired Resistance to Gefitinib Due to RET Overexpression in Lung Cancer2012
- Author(s)
  Sunohara M, Kawakami M, Watanabe K, Morita S, Kage H, Amano Y, Fukayama M, T. Nagase T, Ohishi N, Takai D
- Organizer
  The 24th EORTC-NCI-AACR Symposium on ‘Molecular Targets and Cancer Therapeutics'
- Place of Presentation
  Dublin, Ireland
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] Vandetanib Can Overcome the Aquired Resistance to Gefitinib Due to RET Overexpression in Lung Cancer2012
- Author(s)
  M. Sunohara, M. Kawakami, K. Watanabe, S. Morita, H. Kage, Y. Amano, M. Fukayama, T. Nagase, N. Ohishi, D. Takai
- Organizer
  The 24th EORTC-NCI-AACR Symposium on ‘Molecular Targets and Cancer Therapeutics'
- Place of Presentation
  Dublin, Ireland
- Data Source
  KAKENHI-PROJECT-24659267
[Presentation] Identification of FER as a New Molecular Target in Non-small Cell Lung Cancer2012
- Author(s)
  Kawakami M, Sunohara M, Amano Y, Ishikawa R, Watanabe K, Hamano E, Ohishi N, Nagase T, Yatomi Y, Takai D
- Organizer
  The 24th EORTC-NCIAACR Symposium on 'Molecular Targets and Cancer Therapeutics
- Place of Presentation
  Dublin, Island
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] Vandetanib Can Overcome the Acquired Resistance to Gefitinib Due to RET Overexpression in Lung Cancer2012
- Author(s)
  Sunohara M, Kawakami K, Watanabe K, Morita S, Kage H, Amano Y , Fukayama M, Nagase T, N. Ohishi N, Takai D
- Organizer
  The 24th EORTC-NCI-AACR Symposium on 'Molecular Targets and Cancer Therapeutics
- Place of Presentation
  Dublin, Island
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] Crosstalk Between Alveolar Epithelial Cells And Fibroblasts Through Transforming Growth Factor ・1 And Prostaglandin Synthase 2 Results In Suppression Of Fibroblast Growth2011
- Author(s)
  Kage H, Amano Y, Ishikawa R, Sunohara M, Kawakami M, Emoto N, Watanabe K, Hamano E, Ohishi N, Nagase T, Takai D
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  Denver, CO, USA
- Data Source
  KAKENHI-PROJECT-23390147
[Presentation] 肺癌とエピジェネティクス2009
- Author(s)
  高井大哉
- Organizer
  日本呼吸器学会第49回総会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-06-13
- Data Source
  KAKENHI-PROJECT-20659129
[Presentation] Novel Approach to Identify Methylated. Genes in Non-small Cell Lung Cancer and Methylation of GOS2 as Possible Biomarker of Squamous Lung Cancer.2008
- Author(s)
  Kusakabe M, Takai D et al.
- Organizer
  American Association for Cancer Research Special Conference on Cancer Research Cancer Epigenetics
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2008-05-29
- Data Source
  KAKENHI-PROJECT-19591614
[Presentation] Knockdown of Tgfβ1 with Replication-Defective Serotype 2/5 Adeno-Associated Virus Carrying Short Hairpin RNA2008
- Author(s)
  Kage H, Takai D et al.
- Organizer
  48th Annual Meeting of the Japanese Respiratory Society
- Place of Presentation
  Kobe,Japan
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-20659129
[Presentation] Functional Analysis of PIWIL4 in the induction of H3K9 Methylation at the p16Ink4a Locus2008
- Author(s)
  Aki N, Takai D et al.
- Organizer
  American Association for Cancer Research Special Conference on Cancer Research Cancer Epigenetics
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-20659129
[Presentation] Novel approach to identify methylated genes in non-small cell lung cancer and analyses of methylation Profile2008
- Author(s)
  Kusakabe M, Takai D et al.
- Organizer
  67th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya, Japan
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20659129
[Presentation] Novel approach to identify methylated genes in non-small cell lung cancer and analyses of methylation profile.2008
- Author(s)
  Kusakabe M, Takai D et al.
- Organizer
  67th Annual Meeting of the Japanese Cancer A ssociation
- Place of Presentation
  Nagoya, Japan
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591614
[Presentation] Knockdown of Tgf131 with Replication-Defective Serotype 2/5 Adeno-Associated Virus Carrying Short Hairpin RNA.2008
- Author(s)
  Kage H, Takai D et al.
- Organizer
  48th Annual Meeting of the Japanese Respiratory Society
- Place of Presentation
  Kobe, Japan
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-19591614
[Presentation] Novel approach to identify aberrantlymethylated genes in non-small cell lungcancer and methylation of G0S2 as possiblebiomarker of squamous lung cancer2008
- Author(s)
  Kusakabe M, Kutomi T, Aki N, Kage H, Sano A, Hamano E, Kitagawa H, Murakawa T, Nakajima J, Takamoto S, Ohishi N, NagaseT, Ohta S, Fukayama M, Yatomi Y, Takai D
- Organizer
  American Association for Cacner Research Cancer Epigenetics
- Place of Presentation
  Boston, MA, USA.
- Data Source
  KAKENHI-PROJECT-19591614
[Presentation] Novel Approach to Identify Aberrantly Methylated Genes in Non-small Cell Lung Cancer and Methylation of GOS2 as Possible Biomarker of Squamous Lung Cancer2008
- Author(s)
  Kusakabe M, Takai D et al.
- Organizer
  American Association for Cancer Research Special Conference on Cancer Research Cancer Epigenetics
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2008-05-29
- Data Source
  KAKENHI-PROJECT-20659129
[Presentation] Functional Analysis of PIWIL4 in the induction of H3K9 Methylation at the pl6Ink4a Locus.2008
- Author(s)
  Aki N, Takai D et al.
- Organizer
  American Association for Cancer Research Special Conference on Cancer Research Cancer Epigenetics
- Place of Presentation
  Boston, MA, USA
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-19591614
[Presentation] Knockdown of TgffA1 with Serotype 2/5 Hybrid Adeno-Associated Virus Carrying Short Hairpin RNA2007
- Author(s)
  Kage H, Kutomi T, Kusakabe M, Aki N, Kitagawa H, Ohishi N, Nagase T, Takai D.
- Organizer
  An AACR Special Conference in Cancer Research The Role of Non-Coding RNAs in Cancer
- Place of Presentation
  Hyatt Regency Cambridge Cambridge, Massachusetts
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-19591614
[Presentation] The Induction of H3K9 Methylation by PIWIL4 at the p16^<Ink4a> Iocus2007
- Author(s)
  Aki N, Sugimoto K, Kage H, Sano A, Kutomi T, Kusakabe M, Kitagawa H, Nagase T, Yatomi Y, Ohishi N, Takai D.
- Organizer
  An AACR Special Conference in Cancer Research The Role of Non-Coding RNAs in Cancer
- Place of Presentation
  Hyatt Regency Cambridge Cambridge, Massachusetts
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-19591614
[Presentation] Distinction between doubleprimary lung cancer and intrapulmonarymetastasis using a system for profilingthe DNA methylation status of multiplegene promoters2007
- Author(s)
  Sano A, Kage H, Sugimoto K, Kitagawa H, Aki N, Goto A, Fukayama M, Nakajima J,Takamoto S, Nagase T, Yatomi Y, Ohishi N,Takai D.
- Organizer
  American Association for Cancer Research Annual Meeting 2007
- Place of Presentation
  Boston, MA, USA.
- Data Source
  KAKENHI-PROJECT-19591614
[]

1. NAGASE Takahide (40208004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. SHIMIZU Takao (80127092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KUHIHARA Hiroki (20221947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ISHI Satoshi (10300815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. MURAKAWA Tomohiro (50359626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. NAKAJIMA Jun (90188954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. FUKAMI Takeshi (40396742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 後藤明輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

TAKAI Daiya 高井 大哉

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Chromosomal instability and Clinico-pathologial feature in Lung CancerPrincipal Investigator

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Identification of target for next generation tyrosine kinase inhibitor and clinical markers for sensitive patientsPrincipal Investigator

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肺癌におけるマイクロRNA発現の異常と転写制御崩壊の基礎・臨床的検討Principal Investigator

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The investigation of molecular mechanisms underlying refractory respiratory diseases and exploration of novel therapeutic targets

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Construction of the system for lung cancer treatment based onmethylation profile and EGFR mutation

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ヒトがん細胞におけるゲノムの異常なメチル化の機構の解明Principal Investigator

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ヘアピンsiRNAベクターを用いた炎症性肺疾患治療の標的分子の同定Principal Investigator

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[Book] 統計物理化学から学ぶバイオインフォマティクス2004

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[Book] 統計物理化学から学ぶバイオインフォマティクス2004

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[Journal Article] Combined Large Cell Neuroendocrine Carcinoma and Adenocarcinoma with Epidermal Growth Factor Receptor Mutation in a Female Patient Who Never Smoked2014

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[Journal Article] Detection of novel paraja ring finger 2-fer tyrosine kinase mRNA chimeras is associated with poor postoperative prognosis in non-small cell lung cancer2013

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[Journal Article] High-grade lung adenocarcinoma with fetal-lung-like morphology - Clinicopathological, immunohistochemical, and molecular analyses of 17 cases2013

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[Journal Article] Disruption of the expression and function of microRNAs in lung cancer as a result of epigenetic changes.2013

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[Journal Article] Growth-associated hyperphosphatemia in young recipients accelerates aortic allograft calcification in a rat model2013

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TAKAI Daiya 高井大哉