ISHITANI RYUICHIRO 石谷隆一郎

… Alternative Names

ISHITANI Ryuichiro 石谷隆一郎

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Researcher Number	90361568
Other IDs	https://orcid.org/0000-0002-4136-5685
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 教授 2025: 東京大学, 大学院理学系研究科(理学部), 特任教授
Affiliation (based on the past Project Information) *help	2025: 東京科学大学, 難治疾患研究所, 教授 2018 – 2021: 東京大学, 大学院理学系研究科(理学部), 特任教授 2017 – 2018: 東京大学, 大学院理学系研究科(理学部), 客員共同研究員 2016 – 2017: 東京大学, 大学院理学系研究科(理学部), 准教授 2012 – 2016: 東京大学, 理学(系)研究科(研究院), 准教授 … More 2014: 東京大学, 理学(系)研究科, 准教授 2009 – 2012: 東京大学, 大学院・理学系研究科, 准教授 2007 – 2010: 東京大学, 医科学研究所, 准教授 Less
Review Section/Research Field	Principal Investigator Structural biochemistry / Transformative Research Areas, Section (II) / Biological Sciences / Biological Sciences Except Principal Investigator Biological Sciences / Complex systems / Biological Sciences / Biological Sciences
Keywords	Principal Investigator 膜蛋白質 / X線結晶構造解析 / 薬物動態 / 膜タンパク質 / Ｘ線結晶構造解析 / 多剤耐性菌 / 膜輸送体 / 多剤耐性因子 / 輸送体 / 結晶構造解析 … More / 多剤排出因子 / ドラッグデリバリー / X 線結晶構造解析 / TGF-βシグナル伝達経路 / NF-κBシグナル伝達経路 / 細胞内シグナル伝達 / タンパク質翻訳後修飾 / SecDF / SecYE / トランスコロン … More Except Principal Investigator シグナル伝達 / 蛋白質 / 翻訳後修飾 / Ｘ線 / X線 / 電子顕微鏡 / 生物物理 / 遺伝子 / オミクス解析 / 中心体 / 遺伝子発現制御 / アポトーシス / 免疫応答 / キナーゼ / 新生児呼吸窮迫症候群 / 肺サーファクタント / タンパク質 / 癌 / 生体分子 / 応用数学 / 酸化ストレス / JNK / p38 / ERK / MAPK / ストレス応答 / がん / 数理解析 / 情報科学 / MAPキナーゼ / 構造生物学 / 数理モデル / 疾患 / β-catenineシグナル / Wnt / 低分子量Gタンパク質 / 細胞膜の開口放出 / 細胞骨格再形成 / がん細胞の浸潤 / 薬剤設計 / がん遺伝子 / レセプター / 細胞内ホメオスタシス / TGF-βシグナル / 創薬 / がんの転移 / 発がん / X線結晶構造解析 / 自然免疫 / 転写因子 / 開口放出 / 細胞骨格再構築 / がん細胞の転移 / がん化 Less

深層学習と自動実験による酵素創出技術の高度化Principal Investigator
- Principal Investigator
  
  石谷隆一郎
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Institute of Science Tokyo
タンパク質機能解析と改変に資する蛋白質・化合物複合体の立体構造予測法の構築Principal Investigator
- Principal Investigator
  
  石谷隆一郎
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Institute of Science Tokyo
Structural biology of membrane transporters involved in the efflux mechanism of organic moleculesPrincipal Investigator
- Principal Investigator
  
  Ishitani Ryuichiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
Elucidation of MAPK signaling pathways and biological processes based on mathematical science
- Principal Investigator
  
  Takekawa Mutsuhiro
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Molecular mechanism of membrane proteins regulated by physical stimuli
- Principal Investigator
  
  Nureki Osamu
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Structural biology of multidrug transportersPrincipal Investigator
- Principal Investigator
  
  Ishitani Ryuichiro
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
Regulation of Signal Transduction by Post-translational Modifications and Its Pathogenic Dysregulation
- Principal Investigator
  
  INOUE Jun-ichiro
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Structural basis for protein posttranscriptional modifications and cellular signalingPrincipal Investigator
- Principal Investigator
  
  ISHITANI Ryuichiro
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Structural biology of secondary active transportersPrincipal Investigator
- Principal Investigator
  
  ISHITANI Ryuichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
分子モーターSecA ATPaseによるタンパク質膜透過機構の構造機能相関Principal Investigator
- Principal Investigator
  
  石谷隆一郎
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Structural basis for carcinogenesis and cancer metastasis by oncogene products
- Principal Investigator
  
  NUREKI Osamu
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Tokyo Institute of Technology

[Book] 酵素利用技術大系-基礎・解析から改変・高機能化・産業利用まで-(1章1節2)2010
- Author(s)
  石谷隆一郎、荒磯裕平、野澤佳世
- Total Pages
  800
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PLANNED-22117007
[Book] 酵素利用技術大系-基礎・解析から改変・高機能化・産業利用まで-(1章1節2)2010
- Author(s)
  石谷隆一郎、荒磯裕平、野澤佳世
- Total Pages
  800
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation2020
- Author(s)
  Nakamura Ryoki、Numata Tomohiro、Kasuya Go、Yokoyama Takeshi、Nishizawa Tomohiro、Kusakizako Tsukasa、Kato Takafumi、Hagino Tatsuya、Dohmae Naoshi、Inoue Masato、Watanabe Kengo、Ichijo Hidenori、Kikkawa Masahide、Shirouzu Mikako、Jentsch Thomas J.、Ishitani Ryuichiro、Okada Yasunobu、Nureki Osamu
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 240-240
- DOI
  10.1038/s42003-020-0951-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-20K15754, KAKENHI-PLANNED-16H06574, KAKENHI-PROJECT-18H03995, KAKENHI-PROJECT-18K06864, KAKENHI-PROJECT-19K23833, KAKENHI-PROJECT-16H06294
[Journal Article] Crystal structure of Drosophila Piwi.2020
- Author(s)
  Yamaguchi, S., Oe, A., Nishida, KM., Yamashita, K., Kajiya, A., Hirano, S., Matsumoto, N., Dohmae, N., Ishitani, R., Saito, K., Siomi, H., Nishimasu, H., Siomi, MC., and Nureki, O.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 858-858
- DOI
  10.1038/s41467-020-14687-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05753, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-18H02379, KAKENHI-PROJECT-18H02384, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19H05466, KAKENHI-PLANNED-16H06574
[Journal Article] Structural Basis of H+-Dependent Conformational Change in a Bacterial MATE Transporter2019
- Author(s)
  Kusakizako Tsukasa、Claxton Derek P.、Tanaka Yoshiki、Maturana Andrs D.、Kuroda Teruo、Ishitani Ryuichiro、Mchaourab Hassane S.、Nureki Osamu
- Journal Title
  
  Structure
  
  Volume: 27 Issue: 2 Pages: 293-301
- DOI
  10.1016/j.str.2018.10.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06574, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-16H06294
[Journal Article] Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas92019
- Author(s)
  Hirano Seiichi、Abudayyeh Omar O.、Gootenberg Jonathan S.、Horii Takuro、Ishitani Ryuichiro、Hatada Izuho、Zhang Feng、Nishimasu Hiroshi、Nureki Osamu
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1968-1968
- DOI
  10.1038/s41467-019-09741-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19284, KAKENHI-PLANNED-16H06574, KAKENHI-PROJECT-18H02384, KAKENHI-PROJECT-17J05841
[Journal Article] Structural biology of the multidrug and toxic compound extrusion superfamily transporters2019
- Author(s)
  Kusakizako Tsukasa、Miyauchi Hirotake、Ishitani Ryuichiro、Nureki Osamu
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Biomembranes
  
  Volume: 1 Issue: 12 Pages: 183154-183154
- DOI
  10.1016/j.bbamem.2019.183154
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06574, KAKENHI-PROJECT-17H03640
[Journal Article] Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc2019
- Author(s)
  Lee Yongchan、Wiriyasermkul Pattama、Jin Chunhuan、Quan Lili、Ohgaki Ryuichi、Okuda Suguru、Kusakizako Tsukasa、Nishizawa Tomohiro、Oda Kazumasa、Ishitani Ryuichiro、Yokoyama Takeshi、Nakane Takanori、Shirouzu Mikako、Endou Hitoshi、Nagamori Shushi、Kanai Yoshikatsu、Nureki Osamu
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 26 Issue: 6 Pages: 510-517
- DOI
  10.1038/s41594-019-0237-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06931, KAKENHI-PROJECT-19K07373, KAKENHI-PLANNED-16H06574, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-18K19429, KAKENHI-PROJECT-16H06294
[Journal Article] Structural basis for oligomerization of the prokaryotic peptide transporter PepTSo22019
- Author(s)
  Nagamura Reina、Fukuda Masahiro、Kawamoto Akihiro、Matoba Kyoko、Dohmae Naoshi、Ishitani Ryuichiro、Takagi Junichi、Nureki Osamu
- Journal Title
  
  Acta Crystallographica Section F Structural Biology Communications
  
  Volume: 75 Issue: 5 Pages: 348-358
- DOI
  10.1107/s2053230x19003546
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06574, KAKENHI-PROJECT-17H01420, KAKENHI-PROJECT-18K14639, KAKENHI-PROJECT-18K19298, KAKENHI-PROJECT-16H06294
[Journal Article] Crystal structure of the Agrobacterium tumefaciens type VI effector-immunity complex.2018
- Author(s)
  Fukuhara S, Nakane T, Yamashita K, Ishii R, Ishitani R, Nureki O
- Journal Title
  
  Acta Crystallogr. F Struct. Biol. Commun.
  
  Volume: 74 Issue: 3 Pages: 810-816
- DOI
  10.1038/s41477-019-0367-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-17J06203, KAKENHI-PROJECT-16H06294
[Journal Article] Cap-specific terminal N6-methylation of RNA by an RNA polymerase II?associated methyltransferase2018
- Author(s)
  Akichika Shinichiro、Hirano Seiichi、Shichino Yuichi、Suzuki Takeo、Nishimasu Hiroshi、Ishitani Ryuichiro、Sugita Ai、Hirose Yutaka、Iwasaki Shintaro、Nureki Osamu、Suzuki Tsutomu
- Journal Title
  
  Science
  
  Volume: 363 Issue: 363 Pages: 1-7
- DOI
  10.1126/science.aav0080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07282, KAKENHI-PROJECT-18K19141, KAKENHI-PUBLICLY-17H05592, KAKENHI-ORGANIZER-26113001, KAKENHI-PLANNED-26113003, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19J11333, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-18H05272, KAKENHI-PROJECT-18H02384, KAKENHI-PUBLICLY-17H05679, KAKENHI-PROJECT-17H04998
[Journal Article] Vibrational and Molecular Properties of Mg2+ Binding and Ion Selectivity in the Magnesium Channel MgtE2018
- Author(s)
  Kimura Tetsunari、Lorenz-Fonfria Victor A.、Douki Shintaro、Motoki Hideyoshi、Ishitani Ryuichiro、Nureki Osamu、Higashi Masahiro、Furutani Yuji
- Journal Title
  
  The Journal of Physical Chemistry B
  
  Volume: 122 Issue: 42 Pages: 9681-9696
- DOI
  10.1021/acs.jpcb.8b07967
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0165, KAKENHI-PROJECT-17K05757, KAKENHI-PUBLICLY-17H05882, KAKENHI-PUBLICLY-18H04657, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-16H06294
[Journal Article] An Atomistic Model of a Precursor State of Light-Induced Channel Opening of Channelrhodopsin2018
- Author(s)
  Cheng Cheng, Motoshi Kamiya, Mizuki Takemoto, Ryuichiro Ishitani, Osamu Nureki, *Norio Yoshida, and *Shigehiko Hayashi
- Journal Title
  
  Biophysical Journal
  
  Volume: 115 Issue: 7 Pages: 1281-1291
- DOI
  10.1016/j.bpj.2018.08.024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H05161, KAKENHI-PROJECT-16H04776, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-16J11404, KAKENHI-PROJECT-16K05519, KAKENHI-PROJECT-16H06294
[Journal Article] Functional roles of Mg2+ binding sites in ion-dependent gating of a Mg2+ channel, MgtE, revealed by solution NMR2018
- Author(s)
  Maruyama Tatsuro、Imai Shunsuke、Kusakizako Tsukasa、Hattori Motoyuki、Ishitani Ryuichiro、Nureki Osamu、Ito Koichi、Maturana Andr?s D、Shimada Ichio、Osawa Masanori
- Journal Title
  
  eLife
  
  Volume: 7
- DOI
  10.7554/elife.31596
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-18H04679, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-16H06294
[Journal Article] Crystal structure of the Agrobacterium tumefaciens type VI effector?immunity complex2018
- Author(s)
  Fukuhara Satoshi、Nakane Takanori、Yamashita Keitaro、Ishii Ryohei、Ishitani Ryuichiro、Nureki Osamu
- Journal Title
  
  Acta Crystallographica Section F Structural Biology Communications
  
  Volume: 74 Issue: 12 Pages: 810-816
- DOI
  10.1107/s2053230x18016369
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-16H06574
[Journal Article] Free Energy Landscape for the Entire Transport Cycle of Triose-Phosphate/Phosphate Translocator2018
- Author(s)
  Takemoto M, Lee Y, Ishitani R, Nureki O
- Journal Title
  
  Structure
  
  Volume: 26 Issue: 9 Pages: 1284-1296
- DOI
  10.1016/j.str.2018.05.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-16H06294
[Journal Article] Engineered CRISPR-Cas9 nuclease with expanded targeting space2018
- Author(s)
  Nishimasu Hiroshi、Shi Xi、Ishiguro Soh、Gao Linyi、Hirano Seiichi、Okazaki Sae、Noda Taichi、Abudayyeh Omar O.、Gootenberg Jonathan S.、Mori Hideto、Oura Seiya、Holmes Benjamin、Tanaka Mamoru、Seki Motoaki、Hirano Hisato、Aburatani Hiroyuki、Ishitani Ryuichiro、Ikawa Masahito、Yachie Nozomu、Zhang Feng、Nureki Osamu
- Journal Title
  
  Science
  
  Volume: 361 Issue: 6408 Pages: 1259-1262
- DOI
  10.1126/science.aas9129
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19471, KAKENHI-PROJECT-18K19777, KAKENHI-PLANNED-16H06574, KAKENHI-PUBLICLY-17H05592, KAKENHI-PROJECT-17H01394, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-18H02428, KAKENHI-PROJECT-16J06287, KAKENHI-PROJECT-18H02384
[Journal Article] Cryo-EM structures of the human volume-regulated anion channel LRRC82018
- Author(s)
  Kasuya G, Nakane T, Yokoyama T, Jia Y, Inoue M, Watanabe K, Nakamura R, Nishizawa T, Kusakizako T, Tsutsumi A, Yanagisawa H, Dohmae N, Hattori M, Ichijo H, Yan Z, Kikkawa M, Shirouzu M, Ishitani R, Nureki O
- Journal Title
  
  Nat Struct Mol Biol.
  
  Volume: 25 Issue: 9 Pages: 797-804
- DOI
  10.1038/s41594-018-0109-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-17K15086, KAKENHI-PROJECT-16H06294
[Journal Article] Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 12018
- Author(s)
  Kato Kazuki、Nishimasu Hiroshi、Oikawa Daisuke、Hirano Seiichi、Hirano Hisato、Kasuya Go、Ishitani Ryuichiro、Tokunaga Fuminori、Nureki Osamu
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 4424-4424
- DOI
  10.1038/s41467-018-06922-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06574, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-17H05592, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H02384, KAKENHI-PROJECT-18K06967
[Journal Article] Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA2017
- Author(s)
  Kato K, Omura H, Ishitani R, Nureki O
- Journal Title
  
  Annu Rev Biochem
  
  Volume: 86 Issue: 1 Pages: 541-566
- DOI
  10.1146/annurev-biochem-061516-044813
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03640
[Journal Article] Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf12017
- Author(s)
  Yamano Takashi、Zetsche Bernd、Ishitani Ryuichiro、Zhang Feng、Nishimasu Hiroshi、Nureki Osamu
- Journal Title
  
  Molecular Cell
  
  Volume: 67 Issue: 4 Pages: 633-645
- DOI
  10.1016/j.molcel.2017.06.035
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05592, KAKENHI-PROJECT-17H03640
[Journal Article] Structural basis for xenobiotics extrusion by eukaryotic MATE transporter.2017
- Author(s)
  Miyauchi H., Moriyama S., Kusakizako T., Kumazaki K., Ito K., Dohmae N., Nishizawa T., Miyaji T., Moriyama Y., Ishitani R., Nureki O.
- Journal Title
  
  Nature Commun.
  
  Volume: 8 Issue: 1 Pages: 1633-1633
- DOI
  10.1038/s41467-017-01541-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19489, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-17J02425, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-17H05000
[Journal Article] Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf12017
- Author(s)
  Nishimasu Hiroshi、Yamano Takashi、Gao Linyi、Zhang Feng、Ishitani Ryuichiro、Nureki Osamu
- Journal Title
  
  Molecular Cell
  
  Volume: 67 Issue: 1 Pages: 139-147
- DOI
  10.1016/j.molcel.2017.04.019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05592, KAKENHI-PROJECT-17H03640
[Journal Article] ATP-dependent modulation of MgtE in Mg2+ homeostasis2017
- Author(s)
  Tomita Atsuhiro、Zhang Mingfeng、Jin Fei、Zhuang Wenhui、Takeda Hironori、Maruyama Tatsuro、Osawa Masanori、Hashimoto Ken-ichi、Kawasaki Hisashi、Ito Koichi、Dohmae Naoshi、Ishitani Ryuichiro、Shimada Ichio、Yan Zhiqiang、Hattori Motoyuki、Nureki Osamu
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 148-148
- DOI
  10.1038/s41467-017-00082-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01368, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-16H06294
[Journal Article] Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel2017
- Author(s)
  Kasuya G, Yamaura T, Ma XB, Nakamura R, Takemoto M, Nagumo H, Tanaka E, Dohmae N, Nakane T, Yu Y, Ishitani R, Matsuzaki O, Hattori M, Nureki O
- Journal Title
  
  Nat Commun.
  
  Volume: 8 Issue: 1 Pages: 876-876
- DOI
  10.1038/s41467-017-00887-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-17J06101, KAKENHI-PROJECT-16H06294
[Journal Article] Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA62017
- Author(s)
  Taniguchi Reiya、Inoue Asuka、Sayama Misa、Uwamizu Akiharu、Yamashita Keitaro、Hirata Kunio、Yoshida Masahito、Tanaka Yoshiki、Kato Hideaki E.、Nakada-Nakura Yoshiko、Otani Yuko、Nishizawa Tomohiro、Doi Takayuki、Ohwada Tomohiko、Ishitani Ryuichiro、Aoki Junken、Nureki Osamu
- Journal Title
  
  Nature
  
  Volume: 548 Issue: 7667 Pages: 356-360
- DOI
  10.1038/nature23448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08157, KAKENHI-PUBLICLY-16H00822, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-16J07583, KAKENHI-PROJECT-16J08059, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-17H05000
[Journal Article] Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity.2017
- Author(s)
  Lee Y, Nishizawa T, Takemoto M, Kumazaki K, Yamashita K, Hirata K, Minoda A, Nagatoishi S, Tsumoto K, Ishitani R and Nureki O.
- Journal Title
  
  Nature Plants.
  
  Volume: 3 Issue: 10 Pages: 825-832
- DOI
  10.1038/s41477-017-0022-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-16J07405, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-17H05000
[Journal Article] Structural insights into the nucleotide base specificity of P2X receptors.2017
- Author(s)
  Kasuya G, Fujiwara Y, Tsukamoto H, Morinaga S, Ryu S, Touhara K, Ishitani R, Furutani Y, Hattori M, Nureki O.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 45208-45208
- DOI
  10.1038/srep45208
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01389, KAKENHI-PROJECT-26291030, KAKENHI-PROJECT-26708002, KAKENHI-PROJECT-26640047, KAKENHI-PROJECT-16K15180, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-16H06294
[Journal Article] Structural and functional analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide.2016
- Author(s)
  Omura H, Oikawa D, Nakane T, Kato M, Ishii R, Ishitani R, Tokunaga F, and Nureki O.
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 34756-34756
- DOI
  10.1038/srep34756
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01172, KAKENHI-PUBLICLY-16H01192, KAKENHI-PLANNED-16H06575, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-15K08259, KAKENHI-PROJECT-16K15210
[Journal Article] 3.Mechanisms for Two-Step Proton Transfer Reactions in the Outward-Facing Form of MATE Transporter2016
- Author(s)
  Wataru Nishima, Wataru Mizukami, Yoshiki Tanaka, Ryuichiro Ishitani, Osamu Nureki, Yuji Sugita
- Journal Title
  
  Biophys. J
  
  Volume: 110 Issue: 6 Pages: 1346-1354
- DOI
  10.1016/j.bpj.2016.01.027
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26119006, KAKENHI-PROJECT-25291011
[Journal Article] Data processing pipeline for serial femtosecond crystallography at SACLA2016
- Author(s)
  Nakane T, Joti Y, Tono K, Yabashi M, Nango E, Iwata S, Ishitani R, Nureki O
- Journal Title
  
  J Appl Crystallogr
  
  Volume: 49 Issue: 3 Pages: 1035-1041
- DOI
  10.1107/s1600576716005720
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291011
[Journal Article] Structural Insights into Divalent Cation Modulations of ATP-Gated P2X Receptor Channels2016
- Author(s)
  Kasuya, G., Y. Fujiwara, M. Takemoto, N. Dohmae, Y. Nakada-Nakura, R. Ishitani, M. Hattori, and O. Nureki
- Journal Title
  
  Cell Report
  
  Volume: 14 Issue: 4 Pages: 932-944
- DOI
  10.1016/j.celrep.2015.12.087
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-25670108, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26291030, KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-16H06294
[Journal Article] Crystal structure of silkworm PIWI-clade Argonaute Siwi bound to piRNA2016
- Author(s)
  Matsumoto N, Nishimasu H, Sakakibara K, Nishida KM, Hirano T, Ishitani R, Siomi H, Siomi MC, Nureki O
- Journal Title
  
  Cell
  
  Volume: 167 Issue: 2 Pages: 484-497
- DOI
  10.1016/j.cell.2016.09.002
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01463, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26291010, KAKENHI-PROJECT-15K06948, KAKENHI-PROJECT-16K18556
[Journal Article] Breakpoint cluster region-mediated inflammation is dependent on casein kinase II.2016
- Author(s)
  Meng, J., J-J Jiang, T. Atsumi, H. Bando, Y. Okuyama, L. Sabharwal, I. Nakagawa, H. Higuchi, M. Ota, M. Okawara, R. Ishitani, O. Nureki, D. Higo, Y. Arima, H. Ogura, D. Kamimura and M. Murakami.
- Journal Title
  
  J Immunol.
  
  Volume: 197(8) Issue: 8 Pages: 3111-3119
- DOI
  10.4049/jimmunol.1601082
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04741, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26460574, KAKENHI-PROJECT-15K15147, KAKENHI-PROJECT-15K19122
[Journal Article] Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.2016
- Author(s)
  Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, Ishitani R, Kamei K, Takeyoshi I, Kawakami H, Iwai K, Hatada I, Sawasaki T, Ito H, Nureki O, and Tokunaga F.
- Journal Title
  
  Nat. Commun.
  
  Volume: 7 Issue: 1 Pages: 12547-12547
- DOI
  10.1038/ncomms12547
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01172, KAKENHI-PUBLICLY-16H01192, KAKENHI-PLANNED-16H06575, KAKENHI-PLANNED-16H06579, KAKENHI-PLANNED-24112002, KAKENHI-PROJECT-15H04270, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-16H04729, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-15K18468, KAKENHI-PROJECT-15K08259, KAKENHI-PROJECT-16K15210, KAKENHI-PROJECT-16K18383
[Journal Article] Structural basis for amino-acid export by DMT superfamily transporter YddG2016
- Author(s)
  H. Tsuchiya, S. Doki, M. Takemoto, T. Ikuta, T. Higuchi, K. Fukui, Y. Usuda, E. Tabuchi, S. Nagatoishi, K. Tsumoto, T. Nishizawa, K. Ito, N. Dohmae, R. Ishitani and O. Nureki
- Journal Title
  
  Nature
  
  Volume: 534 Issue: 7607 Pages: 417-420
- DOI
  10.1038/nature17991
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26410190, KAKENHI-PROJECT-15K17882, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-16H02420
[Journal Article] Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems2016
- Author(s)
  Yamada M, Watanabe Y, Gootenberg JS, Hirano H, Ran FA, Nakane T, Ishitani R, Zhang F, Nishimasu H, Nureki O
- Journal Title
  
  Mol Cell
  
  Volume: 65 Issue: 6 Pages: 1109-1121
- DOI
  10.1016/j.molcel.2017.02.007
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01463, KAKENHI-PROJECT-26291010, KAKENHI-PROJECT-17H03640
[Journal Article] Structural basis for specific inhibition of Autotaxin by a DNA aptamer2016
- Author(s)
  Kato, K., Ikeda, H., Miyakawa, S., Futakawa, S., Nonaka, Y., Fujiwara, M., Aoki, J., Morita, J., Ishitani, R., Nishimasu, H., Nakamura, Y., Nureki, O.
- Journal Title
  
  Nature Str. Mol. Biol.
  
  Volume: 印刷中 Issue: 5 Pages: 1-9
- DOI
  10.1038/nsmb.3200
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24241074, KAKENHI-PROJECT-15J08403, KAKENHI-PROJECT-25291011
[Journal Article] Crystal structure of the plant receptor-like kinase TDR in complex with the TDIF peptide.2016
- Author(s)
  Morita, J., Kato, K., Nakane, T., Kondo, Y., Fukuda, H., Nishimasu, H., *Ishitani, R. and *Nureki, O.
- Journal Title
  
  Nat. Commun.
  
  Volume: 7 Issue: 1 Pages: 12383-12383
- DOI
  10.1038/ncomms12383
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01226, KAKENHI-PLANNED-15H05958, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-16H06377
[Journal Article] Crystal structures of the TRIC trimeric intracellular cation channel orthologues.2016
- Author(s)
  Kasuya G, Hiraizumi M, Maturana AD, Kumazaki K, Fujiwara Y, Liu K, Nakada-Nakura Y, Iwata S, Tsukada K, Komori T, Uemura S, Goto Y, Nakane T, Takemoto M, Kato HE, Yamashita K, Wada M, Ito K, Ishitani R, Hattori M, Nureki O.
- Journal Title
  
  Cell Res.
  
  Volume: 26 Issue: 12 Pages: 1288-1301
- DOI
  10.1038/cr.2016.140
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01389, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26291030, KAKENHI-PROJECT-16K15180, KAKENHI-PROJECT-16H06294
[Journal Article] Structure and Engineering of Francisella novicida Cas92016
- Author(s)
  Hisato Hirano, Jonathan S. Gootenberg, Takuro Horii, Omar O. Abudayyeh, Mika Kimura, Takanori Nakane, Ryuichiro Ishitani, Izuho Hatada, Feng Zhang, Hiroshi Nishimasu, Osamu Nureki
- Journal Title
  
  Cell
  
  Volume: 164 Issue: 5 Pages: 950-961
- DOI
  10.1016/j.cell.2016.01.039
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01463, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26291010
[Journal Article] Structure of Cpf1 in Complex with Guide RNA and Target DNA2016
- Author(s)
  Yamano T, Nishimasu H, Zetsche B, Hirano H, Slaymaker IM, Li Y, Fedorova I, Nakane T, Makarova KS, Koonin EV, Ishitani R, Zhang F, Nureki O
- Journal Title
  
  Cell
  
  Volume: 165 Issue: 4 Pages: 946-962
- DOI
  10.1016/j.cell.2016.04.003
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01463, KAKENHI-PROJECT-16J08032, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26291010
[Journal Article] Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas92016
- Author(s)
  Seiichi Hirano, Hiroshi Nishimasu, Ryuichiro Ishitani, Osamu Nureki
- Journal Title
  
  Molecular Cell
  
  Volume: 61 Issue: 6 Pages: 886-894
- DOI
  10.1016/j.molcel.2016.02.018
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01463, KAKENHI-PROJECT-26291010, KAKENHI-PROJECT-25291011
[Journal Article] Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.2016
- Author(s)
  Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 12198-12198
- DOI
  10.1038/ncomms12198
- NAID
  120006957420
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-15J04519, KAKENHI-PROJECT-15J08403, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-16H06294
[Journal Article] LCP crystallization and X-ray diffraction analysis of VcmN, a MATE transporter from Vibrio cholerae.2016
- Author(s)
  2.Kusakizako, T.; Tanaka, Y.; Hipolito, C. J.; Kuroda, T.; Ishitani, R.; Suga, H.; Nureki, O.
- Journal Title
  
  Acta Crystallogr. F Struct. Biol. Commun.
  
  Volume: 72(Pt 7) Issue: 7 Pages: 552-557
- DOI
  10.1107/s2053230x16008931
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06073, KAKENHI-PROJECT-14J09020, KAKENHI-PROJECT-25291011
[Journal Article] Atomistic design of microbial opsin-based blue-shifted optogenetics tools2015
- Author(s)
  Kato HE, Kamiya M, Sugo S, Ito J, Taniguchi R, Orito A, Hirata K, Inutsuka A,Yamanaka A, Maturana AD, Ishitani R, Sudo Y, Hayashi S, Nureki O
- Journal Title
  
  Nat Commun
  
  Volume: 6 Issue: 1 Pages: 7177-7177
- DOI
  10.1038/ncomms8177
- NAID
  120005745621
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640041, KAKENHI-PUBLICLY-15H00878, KAKENHI-PUBLICLY-15H01428, KAKENHI-PLANNED-25104004, KAKENHI-PUBLICLY-26118507, KAKENHI-PROJECT-15H04363, KAKENHI-PROJECT-14J02967, KAKENHI-PROJECT-26860157, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-25291034, KAKENHI-PROJECT-26293046
[Journal Article] Structural basis for Na+ transport mechanism by a light-driven Na+ pump2015
- Author(s)
  H. E. Kato, K. Inoue, R. Abe-Yoshizumi, Y. Kato, H. Ono, M. Konno, S. Hososhima, T. Ishizuka, M. R. Hoque, H. Kunitomo, J. Ito, S. Yoshizawa, K. Yamashita, M. Takemoto, T. Nishizawa, R. Taniguchi, K. Kogure, A. D. Maturana, Y. Iino, H. Yawo, R. Ishitani, H. Kandori*, O. Nureki*
- Journal Title
  
  Nature
  
  Volume: 未定 Issue: 7550 Pages: 48-53
- DOI
  10.1038/nature14322
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22247024, KAKENHI-PUBLICLY-25115701, KAKENHI-PUBLICLY-25115707, KAKENHI-PROJECT-25620011, KAKENHI-PROJECT-25670103, KAKENHI-PROJECT-26430007, KAKENHI-PROJECT-15K15025, KAKENHI-PROJECT-26620005, KAKENHI-PUBLICLY-15H01413, KAKENHI-PLANNED-25104009, KAKENHI-PLANNED-25115010, KAKENHI-PUBLICLY-26115706, KAKENHI-PROJECT-15H02391, KAKENHI-PROJECT-25250001, KAKENHI-PROJECT-15H02800, KAKENHI-PROJECT-15J06631, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-14J02967, KAKENHI-PROJECT-14J40214, KAKENHI-PROJECT-25290002, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26291069, KAKENHI-PROJECT-26708001
[Journal Article] Crystal Structure of Staphylococcus aureus Cas92015
- Author(s)
  Hiroshi Nishimasu, Le Cong, Winston X. Yan, F. Ann Ran, Bernd Zetsche, Yinqing Li, Arisa Kurabayashi, Ryuichiro Ishitani, Feng Zhang, Osamu Nureki
- Journal Title
  
  Cell
  
  Volume: 162 Issue: 5 Pages: 1113-1126
- DOI
  10.1016/j.cell.2015.08.007
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01463, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26291010
[Journal Article] Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin2015
- Author(s)
  Taniguchi R, Kato HE, Font J, Deshpande CN, Wada M, Ito K, Ishitani R, Jormakka M, Nureki O
- Journal Title
  
  Nat. Commun.
  
  Volume: 6 Issue: 1 Pages: 8545-8545
- DOI
  10.1038/ncomms9545
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-24227004
[Journal Article] Molecular dynamics of channelrhodopsin at the early stages of channel opening2015
- Author(s)
  Mizuki Takemoto, Hideaki E. Kato, Michio Koyama, Jumpei Ito, Motoshi Kamiya, Shigehiko Hayashi, Andres D. Maturana, Karl Deisseroth, Ryuichiro Ishitani, and Osamu Nureki
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 6 Pages: 0131094-0131094
- DOI
  10.1371/journal.pone.0131094
- NAID
  120005947158
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104004, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-14J02967, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-25291034
[Journal Article] Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK2015
- Author(s)
  Fukuda M, Takeda H, Kato HE, Doki S, Ito K, Maturana AD, Ishitani R, Nureki O
- Journal Title
  
  Nat. Commun.
  
  Volume: 6 Issue: 1 Pages: 7097-7097
- DOI
  10.1038/ncomms8097
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25291011
[Journal Article] Structural Basis for the Catalytic Mechanism of DncV, Bacterial Homolog of Cyclic GMP-AMP Synthase2015
- Author(s)
  Kazuki Kato, Ryohei Ishii, Seiichi Hirano, Ryuichiro Ishitani, Osamu Nureki
- Journal Title
  
  Structure
  
  Volume: 23 Issue: 5 Pages: 843-850
- DOI
  10.1016/j.str.2015.01.023
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26840016, KAKENHI-PROJECT-25291011
[Journal Article] Structural basis for the facilitative diffusion mechanism by SemiSWEET transporter2015
- Author(s)
  Lee Y, Nishizawa T, Yamashita K, Ishitani R, Nureki O
- Journal Title
  
  Nat Commun
  
  Volume: 6 Issue: 1 Pages: 6112-6112
- DOI
  10.1038/ncomms7112
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-25291011
[Journal Article] Crystal Structure and Activity of the Endoribonuclease Domain of the piRNA Pathway Factor Maelstrom2015
- Author(s)
  Naoki Matsumoto, Kaoru Sato, Hiroshi Nishimasu, Yurika Namba, Kana Miyakubi, Naoshi Dohmae, Ryuichiro Ishitani, Haruhiko Siomi, Mikiko C. Siomi, Osamu Nureki
- Journal Title
  
  Cell Reports
  
  Volume: 11 Issue: 3 Pages: 1-10
- DOI
  10.1016/j.celrep.2015.03.030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25221101, KAKENHI-PROJECT-26291010, KAKENHI-PROJECT-25221003, KAKENHI-PROJECT-13J08341, KAKENHI-PROJECT-26870112, KAKENHI-PROJECT-25291011
[Journal Article] Structure of Saccharomyces cerevisiae mitochondrial Qri7 in complex with AMP2014
- Author(s)
  Tominaga T, Kobayashi K, Ishii R, Ishitani R, Nureki O
- Journal Title
  
  Acta Crystallogr F Struct Biol Commun
  
  Volume: 70 Issue: 8 Pages: 1009-1014
- DOI
  10.1107/s2053230x14014046
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-25291011
[Journal Article] Crystallization and preliminary X-ray diffraction analysis of YidC, a membrane-protein chaperone and insertase from Bacillus halodurans.2014
- Author(s)
  Kumazaki, K., Tsukazaki, T., Nishizawa, T., Tanaka, Y., Kato, H.E., Nakada-Nakura, Y., Hirata, K., Mori, Y., Suga, H., Dohmae, N., Ishitani, R. and Nureki, O.
- Journal Title
  
  Acta Crystallographica Section F Structural Biology Communications
  
  Volume: 70 Issue: 8 Pages: 1056-1060
- DOI
  10.1107/s2053230x14012540
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J08353, KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-25291011, KAKENHI-PLANNED-26119007, KAKENHI-PROJECT-26291023
[Journal Article] The non-canonical hydroxylase structure of YfcM reveals a metal ion-coordination motif required for EF-P hydroxylation2014
- Author(s)
  Kobayashi K, Katz A, Rajkovic A, Ishii R, Branson OE, Freitas MA, Ishitani R, Ibba M, Nureki O
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 42 Issue: 19 Pages: 12295-12305
- DOI
  10.1093/nar/gku898
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-25291011
[Journal Article] Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases2014
- Author(s)
  Araiso Y, Huot JL, Sekiguchi T, Frechin M, Fischer F, Enkler L, Senger B, Ishitani R, Becker HD, Nureki O
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 42 Issue: 9 Pages: 6052-6063
- DOI
  10.1093/nar/gku234
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-25291011
[Journal Article] Crystallization and preliminary X-ray crystallographic analysis of YfcM: an important factor for EF-P hydroxylation2014
- Author(s)
  Kobayashi K, Suzuki T, Dohmae N, Ishitani R, Nureki O
- Journal Title
  
  Acta Crystallogr F Struct Biol Commun
  
  Volume: 70 Issue: 9 Pages: 1236-1239
- DOI
  10.1107/s2053230x14015726
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-25291011
[Journal Article] Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp62014
- Author(s)
  Morita J, Kato K, Mihara E, Ishitani R, Takagi J, Nishimasu H, Aoki J, Nureki O
- Journal Title
  
  Acta Crystallogr F Struct Biol Commun
  
  Volume: 70 Issue: 6 Pages: 794-799
- DOI
  10.1107/s2053230x14008929
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PLANNED-24111006, KAKENHI-PROJECT-25291011
[Journal Article] Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg(2+) channel MgtE2014
- Author(s)
  Takeda H, Hattori M, Nishizawa T, Yamashita K, Shah ST, Caffrey M, Maturana AD, Ishitani R, Nureki O
- Journal Title
  
  Nat Commun
  
  Volume: 5 Issue: 1 Pages: 5374-5374
- DOI
  10.1038/ncomms6374
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-25291011
[Journal Article] Crystal structure of Escherichia coli YidC, a membrane protein chaperone and insertase2014
- Author(s)
  Kumazaki, K., Kishimoto, T., Furukawa, A., Mori, H., Tanaka, Y., Dohmae, N., Ishitani, R., Tsukazaki, T., and Nureki, O.
- Journal Title
  
  Scientific reports
  
  Volume: 4 Issue: 1 Pages: 7299-7299
- DOI
  10.1038/srep07299
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J08353, KAKENHI-PLANNED-22117007, KAKENHI-PLANNED-24117003, KAKENHI-PROJECT-25291011, KAKENHI-PLANNED-26119007, KAKENHI-PROJECT-26291023
[Journal Article] Structural basis for Sec-independent membrane protein insertion by YidC.2014
- Author(s)
  Kumazaki, K., Chiba, S., Takemoto, M., Furukawa, A., Nishiyama, K., Sugano, Y., Mori, T., Dohmae, N., Hirata, K., Nakada-Nakura, Y., Maturana, A.D., Tanaka, Y., Mori, H., Sugita, Y., Arisaka, F., Ito K., Ishitani, R., Tsukazaki, T. and Nureki, O.
- Journal Title
  
  Nature
  
  Volume: 509 Issue: 7501 Pages: 516-520
- DOI
  10.1038/nature13167
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J08353, KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-23570190, KAKENHI-PLANNED-24117003, KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-24687016, KAKENHI-PROJECT-25291009, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-25660073, KAKENHI-PUBLICLY-26102532, KAKENHI-PUBLICLY-26102703, KAKENHI-PUBLICLY-26119701, KAKENHI-PROJECT-26291023
[Journal Article] Crystal structure of a claudin provides insight into the architecture of tight junctions2014
- Author(s)
  Suzuki H, Nishizawa T, Tani K, Yamazaki Y, Tamura A, Ishitani R, Dohmae N, Tsukita S, Nureki O, Fujiyoshi Y
- Journal Title
  
  Science
  
  Volume: 344 Issue: 6181 Pages: 304-307
- DOI
  10.1126/science.1248571
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22227004, KAKENHI-PROJECT-22770147, KAKENHI-PROJECT-24227004, KAKENHI-PUBLICLY-25114708, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-25650019, KAKENHI-PROJECT-26440024, KAKENHI-PROJECT-26640057, KAKENHI-PLANNED-24113002, KAKENHI-PROJECT-24247037
[Journal Article] Screening and X-ray crystal structure-based optimization of autotaxin (ENPP2) inhibitors, using a newly developed fluorescence probe2013
- Author(s)
  Mitsuyasu Kawaguchi
- Journal Title
  
  ACS chemical biology
  
  Volume: 8 Issue: 8 Pages: 1713-1721
- DOI
  10.1021/cb400150c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J10869, KAKENHI-PROJECT-22000006, KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-23687014, KAKENHI-PUBLICLY-25116705, KAKENHI-PROJECT-25291011
[Journal Article] Crystal structure of Cex1p reveals the mechanism of tRNA trafficking between nucleus and cytoplasm2013
- Author(s)
  Nozawa K, Ishitani R, Yoshihisa T, Sato M, Arisaka F, Kanamaru S, Dohmae N, Mangroo D, Senger B, Becker HD, Nureki O
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 41 Pages: 3901-3901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Structural Basis for the Counter-Transport Mechanism of a H+/Ca2+ Exchanger2013
- Author(s)
  Nishizawa T, Kita S, Maturana AD, Furuya N, Hirata K, Kasuya G, Ogasawara S, Dohmae N, Iwamoto T, Ishitani R, Nureki O
- Journal Title
  
  Science
  
  Volume: 341 Issue: 6142 Pages: 168-172
- DOI
  10.1126/science.1239002
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-23590319, KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-24570150, KAKENHI-PUBLICLY-25136722, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-25460350, KAKENHI-PROJECT-25650019
[Journal Article] Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT.2013
- Author(s)
  Doki S, Kato HE, Solcan N, Iwaki M, Koyama M, Iwase N, Tsukazaki T, Hattori M, Sugita Y, Kandori H, Newstead S, Ishitani R ,Nureki O.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: (掲載決定)
- NAID
  130003391407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Backbone resonance assignments for the cytoplasmic region of the Mg(2+) transporter MgtE in the Mg (2+)-unbound state2013
- Author(s)
  Maruyama T, Imai S, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I.
- Journal Title
  
  Biomol NMR Assign
  
  Volume: 7 Issue: 1 Pages: 93-96
- DOI
  10.1007/s12104-012-9385-y
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-21590040, KAKENHI-PROJECT-22687007, KAKENHI-PUBLICLY-23107708, KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-25121707
[Journal Article] Screening and X-Ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe.2013
- Author(s)
  Kawaguchi M, Okabe T, Okudaira S, Nishimasu H, Ishitani R, Kojima H, Nureki O, Aoki J, Nagano T.
- Journal Title
  
  ACS Chem Biol
  
  Volume: (掲載決定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Structural and functional analyses of DNA-sensing and immune activation by human cGAS2013
- Author(s)
  Kazuki Kato, Ryohei Ishii, Eiji Goto, Ryuichiro Ishitani, Fuminori Tokunaga, and Osamu Nureki
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 10 Pages: e76983-e76983
- DOI
  10.1371/journal.pone.0076983
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117006, KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-25670137, KAKENHI-PROJECT-25860207
[Journal Article] Structural basis for the drug extrusion mechanism by a MATE multidrug transporter.2013
- Author(s)
  Tanaka Y, Hipolito CJ, Maturana AD, Ito K, Kuroda T, Higuchi T, Katoh T, Kato HE, Hattori M, Kumazaki K, Tsukazaki T, Ishitani R, Suga H, Nureki O.
- Journal Title
  
  Nature
  
  Volume: 496 Pages: 247-251
- NAID
  120005716854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT.2013
- Author(s)
  Doki, S., Kato, H. E., Solcan, N., Iwaki, M., Koyama, M., Iwase, N., Tsukazaki, T., Sugita, Y., Kandori, H., Newstead, S., Ishitani, R., and Nureki, O.
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States
  
  Volume: 110 Issue: 28 Pages: 11343-11348
- DOI
  10.1073/pnas.1301079110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06643, KAKENHI-PROJECT-12J07636, KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22247024, KAKENHI-PUBLICLY-24121704, KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-24687016, KAKENHI-PLANNED-25104009, KAKENHI-PROJECT-25291011
[Journal Article] Structural basis for the drug extrusion mechanism by a MATE multidrug transporter2013
- Author(s)
  Y・ Tanaka, C・J・ Hipolito, A・D・ Maturana, K・ Ito, T・ Kuroda, T・ Higuchi, T・ Katoh, H・E・ Kato, M・ Hattori, K・ Kumazaki, T・ Tsukazaki, R・ Ishitani, H・ Suga, O・ Nureki
- Journal Title
  
  Nature
  
  Volume: 496 Issue: 7444 Pages: 247-51
- DOI
  10.1038/nature12014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01344, KAKENHI-PROJECT-11J06643, KAKENHI-PROJECT-21000005, KAKENHI-PLANNED-22117007, KAKENHI-PUBLICLY-24121704, KAKENHI-PROJECT-24227004, KAKENHI-PROJECT-24570150, KAKENHI-PROJECT-24681047, KAKENHI-PROJECT-24687016, KAKENHI-PROJECT-25291011
[Journal Article] Structural Basis for Potent Inhibition of SIRT2 Deacetylase by a Macrocyclic Peptide Inducing Dynamic Structural Change2013
- Author(s)
  Yamagata, K., Goto, Y., Nishimasu, H., Morimoto, J., Ishitani, R., Dohmae, N., Takeda, N., Nagai, R., Komuro, I., Suga, H., Nureki, O
- Journal Title
  
  Structure
  
  Volume: 22 Issue: 2 Pages: 345-352
- DOI
  10.1016/j.str.2013.12.001
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-23687014, KAKENHI-PUBLICLY-25116705, KAKENHI-PROJECT-25291011
[Journal Article] Structural Basis for the Counter-Transport Mechanism of a H+/Ca2+ Exchanger.2013
- Author(s)
  Nishizawa T, Kita S, Maturana AD,Furuya N, Hirata K, Kasuya G, Ogasawara S,Dohmae N, Iwamoto T, Ishitani R, NurekiO.
- Journal Title
  
  Science
  
  Volume: (掲載決定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Crystal structure of Cex1p reveals the mechanism of tRNA trafficking between nucleus and cytoplasm2013
- Author(s)
  K. Nozawa, R. Ishitani, T. Yoshihisa, M. Sato, F. Arisaka, S. Kanamaru, N. Dohmae, D. Mangroo, B. Senger, H. D. Becker and O. Nureki
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 41 Issue: 6 Pages: 3901-3914
- DOI
  10.1093/nar/gkt010
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-21113001, KAKENHI-PLANNED-21113002, KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22570139, KAKENHI-PROJECT-23570190, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-25291037, KAKENHI-PROJECT-25440066, KAKENHI-PUBLICLY-23112708
[Journal Article] Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp12012
- Author(s)
  Kato K, Nishimasu H, Mihara E, Ishitani R, Takagi J, Aoki J, Nureki O
- Journal Title
  
  Acta Crystallogr
  
  Volume: F68 Issue: 7 Pages: 778-782
- DOI
  10.1107/s1744309112019306
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22247010, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23687014, KAKENHI-PROJECT-24651260, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111006
[Journal Article] Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation2012
- Author(s)
  Tokunaga F, Nishimasu H, Ishitani R, Goto E, Noguchi T, Mio K, Kamei K, Ma A, Iwai K, Nureki O
- Journal Title
  
  EMBO J.
  
  Volume: 31 Issue: 19 Pages: 3856-3870
- DOI
  10.1038/emboj.2012.241
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22249008, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23390070, KAKENHI-PROJECT-23591263, KAKENHI-PROJECT-23657075, KAKENHI-PROJECT-23687014, KAKENHI-PROJECT-23700517, KAKENHI-PROJECT-24659136, KAKENHI-PLANNED-22117006, KAKENHI-ORGANIZER-24112001, KAKENHI-PLANNED-24112002
[Journal Article] A 3D view of autotaxin2012
- Author(s)
  Nishimasu H, Ishitani R, Aoki J, Nureki O
- Journal Title
  
  Trends Pharmacol Sci
  
  Volume: 33 Issue: 3 Pages: 138-145
- DOI
  10.1016/j.tips.2011.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390015, KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22659013, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23687014
[Journal Article] Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Zucchini from Drosophila melanogaster2012
- Author(s)
  Fukuhara S, Nishimasu H, Bonnefond L, Matsumoto N, Ishitani R, Nureki O
- Journal Title
  
  Acta Crystallogr
  
  Volume: F68 Issue: 11 Pages: 1346-1350
- DOI
  10.1107/s1744309112038936
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23687014
[Journal Article] Crystal structure of the channelrhodopsin light-gated cation channel.2012
- Author(s)
  Kato HE, Zhang F, Yizhar O, RamakrishnanC, Nishizawa T, Hirata K, Ito J, Aita Y, Tsukazaki T, Hayashi S, Hegemann P, Maturana AD, Ishitani R, Deisseroth K, Nureki O.
- Journal Title
  
  Nature
  
  Volume: 482 Pages: 369-374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Simplification of the genetic code: restricted diversity of genetically encoded amino acids2012
- Author(s)
  Kawahara-Kobayashi A, Masuda A, Araiso Y, Sakai Y, Kohda A, Uchiyama M, Asami S, Matsuda T, Ishitani R, Dohmae N, Yokoyama S, Kigawa T, Nureki O, Kiga D
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 40 Issue: 20 Pages: 10576-10576
- DOI
  10.1093/nar/gks786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23650155, KAKENHI-PLANNED-23119005
[Journal Article] Molecular Dynamics Simulation of Autotaxin: Roles of the Nuclease-like Domain and the Glycan Modification.2012
- Author(s)
  Koyama M, Nishimasu H, Ishitani R , Nureki O.
- Journal Title
  
  J Phys Chem B
  
  Volume: 116 Pages: 11798-11808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Structure and function of Zucchini endoribonuclease in piRNA biogenesis.2012
- Author(s)
  Nishimasu H, Ishizu H, Saito K, Fukuhara S, Kamatani MK, Bonnefond L, Matsumoto N, Nishizawa T, Nakanaga K, Aoki J, Ishitani R, Siomi H, Siomi MC, Nureki O.
- Journal Title
  
  Nature
  
  Volume: 491 Pages: 284-287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition2012
- Author(s)
  Ishii R
- Journal Title
  
  EMBO Journal
  
  Volume: 31 Issue: 11 Pages: 2541-2552
- DOI
  10.1038/emboj.2012.77
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112002, KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22390052, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23570190
[Journal Article] Crystal structure of the channelrhodopsin light-gated cation channel2012
- Author(s)
  Hideaki E.Kato, Feng Zhang, Ofer Yizhar, Charu Ramakrishnan, Tomohiro Nishizawa, Kunio Hirata, Jumpei Ito, Yusuke Aita, Tomoya Tsukazaki, Shigehiko Hayashi, Peter Hegemann, Andres D.Maturana, Ryuichiro Ishitani, Karl Deisseroth, Osamu Nureki
- Journal Title
  
  Nature
  
  Volume: 482 Issue: 7385 Pages: 369-374
- DOI
  10.1038/nature10870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06643, KAKENHI-PROJECT-20227003, KAKENHI-PROJECT-21770135, KAKENHI-PUBLICLY-22020008, KAKENHI-PLANNED-22117007, KAKENHI-PUBLICLY-22121503, KAKENHI-PROJECT-22687007, KAKENHI-PUBLICLY-23107717, KAKENHI-PROJECT-24687016, KAKENHI-PUBLICLY-24121704
[Journal Article] The tRNA recognition mechanism of folate/FAD-dependent tRNA methyltransferase (TrmFO)2012
- Author(s)
  Yamagami R, Yamashita K, Nishimasu H, Tomikawa C, Ochi A, Iwashita C, Hirata A, Ishitani R, Nureki O, Hori H
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 51 Pages: 42480-42480
- DOI
  10.1074/jbc.m112.390112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23350081, KAKENHI-PROJECT-23687014, KAKENHI-PROJECT-24655156
[Journal Article] Molecular Dynamics Simulation of Autotaxin : Roles of the Nuclease-like Domain and the Glycan Modification.2012
- Author(s)
  Michio Koyama, Hiroshi Nishimasu, Ryuichiro Ishitani, Osamu Nureki
- Journal Title
  
  J. Phys. Chem. B
  
  Volume: 116 Issue: 39 Pages: 11798-11808
- DOI
  10.1021/jp303198u
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J09861, KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23687014
[Journal Article] Structure and function of Zucchini endoribonuclease in piRNA biogenesis.2012
- Author(s)
  Hiroshi Nishimasu, Hirotsugu Ishizu
- Journal Title
  
  Nature
  
  Volume: 491 Issue: 7423 Pages: 284-287
- DOI
  10.1038/nature11509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J56562, KAKENHI-PROJECT-11J05211, KAKENHI-PROJECT-20221008, KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23687014, KAKENHI-PROJECT-24227004
[Journal Article] Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling2012
- Author(s)
  Kato K, Nishimasu H, Okudaira S, Mihara E, Ishitani R, Takagi J, Aoki J, Nureki O
- Journal Title
  
  Proc. Natl Acad. Sci. U. S. A.
  
  Volume: 109 Issue: 42 Pages: 16876-16881
- DOI
  10.1073/pnas.1208017109
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22247010, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23687014, KAKENHI-PROJECT-24651260, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111006
[Journal Article] Spatial distribution of cytoplasmic domains of the Mg2+-transporter MgtE, in a solution lacking Mg2+, revealed by paramagnetic relaxation enhancement.2012
- Author(s)
  Imai S, Maruyama T, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1824 Pages: 1129-1135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Structural basis for trans lation termination by archaeal RF1 and GTP-bound EF1α complex.2012
- Author(s)
  Kobayashi K, Saito K, Ishitani R , Ito K, Nureki O.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 40 Pages: 9319-9328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Spatial distribution of cytoplasmic domains of the Mg(2+)-transporter MgtE, in a solution lacking Mg(2+), revealed by paramagnetic relaxation enhancement2012
- Author(s)
  Imai S, Maruyama T, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1824 Issue: 10 Pages: 1129-1135
- DOI
  10.1016/j.bbapap.2012.06.008
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-23107708, KAKENHI-ORGANIZER-21121001
[Journal Article] Structural basis for translation termination by archaeal RF1 and GTP-bound EF1α complex.2012
- Author(s)
  Kan Kobayashi, Kazuki Saito, Ryuichiro Ishitani, Koichi Ito, Osamu Nureki
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 40 Issue: 18 Pages: 9319-9328
- DOI
  10.1093/nar/gks660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06792, KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22310134, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23657071
[Journal Article] Crystallization and preliminary X-ray diffraction of the first periplasmic domain of SecDF, a translocon-associated membrane protein, from Thermus thermophilus2011
- Author(s)
  Echizen Y, Tsukazaki T, Dohmae N, Ishitani R, Nureki O
- Journal Title
  
  Acta Cryst
  
  Volume: F67 Issue: 4 Pages: 376-380
- DOI
  10.1107/s1744309106007779
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22687007
[Journal Article] Crystal structure of autotaxin and insight into GPCR activation by lipid mediators2011
- Author(s)
  Nishimasu H, 他, Ishitani R, Takagi J, Aoki J, Nureki O
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 18 Pages: 205-212
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007
[Journal Article] Structure and function of a membrane component SecDF that enhances protein export2011
- Author(s)
  T.Tsukazaki, H.Mori, Y.Echizen, R.Ishitani, S.Fukai, T.Tanaka, A.rederina, D.G.Vassylyev, T.Kohno, A.D.Maturana, K.Ito, O.Nureki
- Journal Title
  
  Nature in press
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification2011
- Author(s)
  Kato M, (他), Ishitani R, Nureki O
- Journal Title
  
  Nucleic Acids Res
  
  Volume: (未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] C-terminal domain of archaeal O-phosphoseryl-tRNA kinase displays large-scale motion to bind the 7-bp D-stem of archaeal tRNASec2011
- Author(s)
  Sherrer RL, (他) Ishitani R, Ho JM, Soll D, Nureki O
- Journal Title
  
  Nucleic Acids Res
  
  Volume: (未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] tructure and function of SecDF, a protein export-enhancing membrane component2011
- Author(s)
  Tsukazaki, T., et al
- Journal Title
  
  Nature
  
  Volume: 475 Issue: 7350 Pages: 235-238
- DOI
  10.1038/nature09980
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19058007, KAKENHI-PROJECT-20227003, KAKENHI-PROJECT-20247020, KAKENHI-PROJECT-21687009, KAKENHI-PROJECT-21770135, KAKENHI-PUBLICLY-22020008, KAKENHI-PUBLICLY-22020035, KAKENHI-PLANNED-22117007, KAKENHI-PUBLICLY-22117503, KAKENHI-PLANNED-22121003, KAKENHI-PUBLICLY-22121503, KAKENHI-PROJECT-22370070, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23657128
[Journal Article] Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog2011
- Author(s)
  Bonnefond L, (他), Ishitani R, Nureki O.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 108 Pages: 3912-3917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Crystal structure of autotaxin and insight into GPCR activation by lipid mediators2011
- Author(s)
  Nishimasu H, (他), Ishitani R, Takagi J, Aoki J, Nureki O
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 18 Pages: 205-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Crystal structure of autotaxin and insight into GPCR activation by lipid mediators2011
- Author(s)
  H.Nishimasu, S.Okudaira, K.Hama, E.Mihara, N.Dohmae, A.Inoue, R.Ishitani, J.Takagi, J.Aoki, O.Nureki
- Journal Title
  
  Nat.Struct.Mol.Biol. 18
  
  Pages: 205-212
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog2011
- Author(s)
  L.Bonnefond, T.Arai, Y.Sakaguchi, T.Suzuki, R.Ishitani, O.Nureki
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 108
  
  Pages: 3912-3917
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Structural basis for nonribosomal peptide synthesis by an aminoacyl-tRNA synthetase paralog2011
- Author(s)
  Bonnefond L, (他), Ishitani R, Nureki O.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 108 Pages: 3912-3917
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007
[Journal Article] Omnipotent role of archaeal elongation factor 1 alpha (EF1α in translational elongation and termination, and quality control of protein synthesis2010
- Author(s)
  K.Saito, K.Kobayashi, M.Wada, I.Kikuno, A.Takusagawa, M.Mochizuki, T.Uchiumi, R.Ishitani, O.Nureki, K.Ito
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 107
  
  Pages: 19242-19247
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Omnipotent role of archaeal elongation factor 1 alpha (EF1α) in translational elongation and termination, and quality control of protein synthesis.2010
- Author(s)
  Saito K, Kobayashi K, (他), Ishitani R, Nureki O, Ito K
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 107 Pages: 19242-19247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Structural Basis for mRNA Surveillance by Archaeal Pelota and GTP-bound EF1? Complex2010
- Author(s)
  K.Kobayashi, I.Kikuno, K.Kuroha, K.Saito, K.Ito, R.Ishitani, T.Inada, O.Nureki
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. 107
  
  Pages: 17575-17579
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Molecular mechanisms underlying the early stage of protein translocation through the Sec translocon2010
- Author(s)
  Mori T, Ishitani R, Tsukazaki T, Nureki O, Sugita Y
- Journal Title
  
  Biochemistry
  
  Volume: 49 Pages: 945-950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Structure of an archaeal non-discriminating glutamyl-tRNA synthetase : a missing link in the evolution of Gln-tRNAGln formation2010
- Author(s)
  Nureki O, (他), Ishitani R
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 38 Pages: 7286-7297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Omnipotent role of archaeal elongation factor 1 alpha (EF1α) in translational elongation and termination, and quality control of protein synthesis.2010
- Author(s)
  Saito K, Kobayashi K, (他), Ishitani R, Nureki O, Ito K
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 107 Pages: 19242-19247
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007
[Journal Article] Molecular mechanisms underlying the early stage of protein translocation through the Sec translocon2010
- Author(s)
  Mori T, Ishitani R, Tsukazaki T, Nureki O, Sugita Y
- Journal Title
  
  Biochemistry
  
  Volume: 49 Pages: 945-950
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007
[Journal Article] Expanding role of the Jumonji C domain as an RNA hydroxylase2010
- Author(s)
  Noma A, Ishitani R, Kato M, Nagao A, Nureki O, Suzuki T
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 34503-7
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007
[Journal Article] C-terminal domain of archaeal O-phosphoseryl-tRNA kinase displays large-scale motion to bind the 7-bp D-stem of archaeal tRNASec2010
- Author(s)
  Sherrer RL, (他), Ishitani R, Ho JM, Soll D, Nureki O
- Journal Title
  
  Nucleic Acids Res
  
  Volume: (掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007
[Journal Article] Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1α complex2010
- Author(s)
  Kobayashi K, (他), Ishitani R, Inada T, Nureki O
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 107 Pages: 17575-17579
- NAID
  10030494636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1α complex2010
- Author(s)
  Kobayashi K, (他), Ishitani R, Inada T, Nureki O
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 107 Pages: 17575-17579
- NAID
  10030494636
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007
[Journal Article] Structure of an archaeal non-discriminating glutamyl-tRNA synthetase : a missing link in the evolution of Gln-tRNAGln formation2010
- Author(s)
  Nureki O, (他), Ishitani R
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 38 Pages: 7286-7297
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007
[Journal Article] Expanding role of the Jumonji C domain as an RNA hydroxylase2010
- Author(s)
  Noma A, Ishitani R, Kato M, Nagao A, Nureki O, Suzuki T
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 34503-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687007
[Journal Article] Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification2010
- Author(s)
  Kato M, (他), Ishitani R, Nureki O
- Journal Title
  
  Nucleic Acids Res
  
  Volume: (掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117007
[Journal Article] Structural basis for translational fidelity ensured by tRNA lysidine synthetase2009
- Author(s)
  K.Nakanishi, L.Bonnefond, S.Kimura, T.Suzuki, R.Ishitani, O.Nureki.
- Journal Title
  
  Nature 461
  
  Pages: 1144-1148
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Mg^<2+>-dependent gating of bacterial MgtE channel underlies Mg^<2+> homeostasis2009
- Author(s)
  M.Hattori, N.Iwase, N.Furuya, Y.Tanaka, T.Tsukazaki, R.Ishitani, M.E.Maguire, K.Ito, A.Maturana, O.Nureki
- Journal Title
  
  EMBO J 28
  
  Pages: 3602-3612
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW22009
- Author(s)
  Umitsu M, (他3名), Ishitani R, Nureki O
- Journal Title
  
  Proc Natl Acad Sci USA 106
  
  Pages: 15616-21
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21023005
[Journal Article] Crystallization and preliminary X-ray diffraction analysis of GCIP/HHM transcriptional regulator2009
- Author(s)
  A.Seto, H.Ikushima, T.Suzuki, Y.Sato, S.Fukai, K.Yuki, K.Miyazawa, K.Miyazono, R.Ishitani, O.Nureki
- Journal Title
  
  Acta Crystallogr.Sect.F. 65
  
  Pages: 21-24
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Mg^<2+>-dependent gating of bacterial MgtE channel underlies Mg^<2+> homeostasis2009
- Author(s)
  Hattori M, (他3名), Tsukazaki T, Ishitani R, (他3名), Nureki O
- Journal Title
  
  EMBO J 28
  
  Pages: 3602-12
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21023005
[Journal Article] Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase2009
- Author(s)
  Nakanishi K, (他3名), Ishitani R, Nureki O
- Journal Title
  
  Nature 461
  
  Pages: 1144-8
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21023005
[Journal Article] Crystal structure of the cytosolic domain of the cation diffusion facilitator family protein2009
- Author(s)
  Higuchi T, Hattori M, Tanaka Y, Ishitani R, Nureki O
- Journal Title
  
  Proteins 76
  
  Pages: 768-71
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21023005
[Journal Article] Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase2009
- Author(s)
  H.Nishimasu, R.Ishitani, K.Yamashita, C.Iwashita, A.Hirata, H.Hori, O.Nureki
- Journal Title
  
  Proc.Natl.Acad.USA. 106
  
  Pages: 8180-8185
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Pyrrolysyl-tRNA synthetase-tRNA(Pyl) structure reveals the molecular basis of orthogonality2009
- Author(s)
  K.Nozawa, P.O'Donoghue, S.Gundllapalli, Y.Araiso, R.Ishitani, T.Umehara, D.Soll, O.Nureki
- Journal Title
  
  Nature 457
  
  Pages: 1163-1167
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Structural Basis of Novel Interactions Between the Small-GTPase and GDI-like Domains in Prokaryotic FeoB Iron Transporter2009
- Author(s)
  Hattori M, (他5名), Ishitani R, Ito K, Nureki O
- Journal Title
  
  Structure 17
  
  Pages: 1345-55
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21023005
[Journal Article] Structural basis of AdoMet-dependent aminocarboxypropyl transfer reaction catalyzed by tRNA-wybutosine synthesizing enzyme, TYW2.2009
- Author(s)
  M.Umitsu, H.Nishimasu, A.Noma, T.Suzuki, R.Ishitani, O.Nureki
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. 106
  
  Pages: 15616-15621
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Structure of a tRNA-dependent kinase essential for selenocysteine decoding.2009
- Author(s)
  Y.Araiso, R.L.Sherrer, R.Ishitani, J.M.L.Ho, D.Soll, O.Nureki.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. 106
  
  Pages: 16215-16220
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase2009
- Author(s)
  Nishimasu H, Ishitani R, (他4名), Nureki O
- Journal Title
  
  Proc Natl Acad Sci USA 106
  
  Pages: 8180-5
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21023005
[Journal Article] Structure of a tRNA-dependent kinase essential for selenocysteine decoding2009
- Author(s)
  Araiso Y, Sherrer RL, Ishitani R, (他2名), Nureki O
- Journal Title
  
  Proc Natl Acad Sci USA 106
  
  Pages: 16215-20
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21023005
[Journal Article] Structural basis of novel interactions between the small-GTPase and GDI-like domains in prokaryotic FeoB iron transporter.2009
- Author(s)
  M.Hattori, Y.Jin, H.Nishimasu, Y.Tanaka, M.Mochizuki, T.Uchiumi, R.Ishitani, K.Ito, O.Nureki.
- Journal Title
  
  Structure 17
  
  Pages: 1345-1355
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Conformational transition of Sec machinery inferred from bacterial SecYE structures2008
- Author(s)
  T.Tsukazaki, H.Mori, S.Fukai, R.Ishitani, T.Mori, N.Dohmae, A.Perederina, Y.Sugita, D.G.Vassylyev, K.Ito, O.Nureki
- Journal Title
  
  Nature 455
  
  Pages: 988-991
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Mg^<2+>-sensing mechanism of Mg^<2+> transporter MgtE probed by molecular dynamics study2008
- Author(s)
  R.Ishitani, Y.Sugita, N.Dohmae, N.Furuya, M.Hattori, O.Nureki
- Journal Title
  
  Proc.Natl.Acad.USA. 105
  
  Pages: 15393-15398
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Crystallization and preliminary X-ray diffraction analysis of GCIP/HRM transcriptional regulator2008
- Author(s)
  A. Seto, H. Ikushima, T. Suzuki , Y. Sato, S. Fukai, K. Yuki, K. Miyazawa, K. Miyazono, R. Ishitani and O. Nureki
- Journal Title
  
  Acta Crystallogr. Sect. F. 65
  
  Pages: 21-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Crystal structure of the Sec4p・Sec2p complex in the nucleotide exchanging intermediatetate2007
- Author(s)
  Y.Sato, S.Fukai, R.Ishitani, O.Nureki
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 104
  
  Pages: 8305-8310
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Crystal structure of the MgtE Mg2+ transporter2007
- Author(s)
  M Hattori, Y.Tanaka, S.Fukai, R.Ishitani, O.Nureki
- Journal Title
  
  Nature 448
  
  Pages: 1072-1075
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Crystal structure of the Sec4poSec2p complex in the nucleotide exchanging intermediate state2007
- Author(s)
  Y.Sato, S.Fukai, R.Ishitani, O.Nureki
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 21(in press)
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Complete crystallographic analysis of the dynamics of CCA-addition2006
- Author(s)
  K.Tomita, R.Ishitani, S.Fukai, O.Nureki
- Journal Title
  
  Nature 443
  
  Pages: 956-960
- NAID
  130006997728
- Data Source
  KAKENHI-PROJECT-17012009
[Journal Article] Structural basis of RNA-dependent recruitment of glutamine to the genetic code2006
- Author(s)
  H.Oshikane, K.Sheppard, S.Fukai, Y.Nakamura, R.Ishitani, T.Numata, L.R.Sherrer, L.Feng, E.Schmitt, M.Panvert, S.Blanquet, Y.Mechulam, D.Soll, O.Nureki
- Journal Title
  
  Science 312
  
  Pages: 1950-1954
- Data Source
  KAKENHI-PROJECT-17012009
[Presentation] Structural basis for amino acid export by DMT superfamily transporter YddG2016
- Author(s)
  Ryuichiro Ishitani
- Organizer
  GRC Membrane Transport Proteins
- Place of Presentation
  Lucca (Barga), Italy
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291011
[Presentation] 膜輸送体の分子メカニズム2016
- Author(s)
  石谷隆一郎
- Organizer
  分子生物学会第３９回年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291011
[Presentation] Structural Basis for Dynamic Mechanism of Nitrate/Nitrite Antiport by NarK2015
- Author(s)
  Ryuichiro Ishitani
- Organizer
  GRC Mechanisms of Membrane Transport
- Place of Presentation
  Bates College, Lewiston, ME, USA
- Year and Date
  2015-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291011
[Presentation] 先端放射光を用いたチャネル・トランスポーターの高分解能構造解析と分子機構の解明2015
- Author(s)
  石谷隆一郎
- Organizer
  日本放射光学会
- Place of Presentation
  立命館大学びわこ･くさつキャンパス
- Year and Date
  2015-01-11
- Invited
- Data Source
  KAKENHI-PROJECT-25291011
[Presentation] プロトンで駆動されるトランスポーターの分子機構2015
- Author(s)
  石谷隆一郎
- Organizer
  分子研研究会「膜タンパク質内部のプロトン透過を考える」
- Place of Presentation
  岡崎コンファレンスセンター愛知県岡崎市明大寺町伝馬８－１
- Year and Date
  2015-04-20
- Invited
- Data Source
  KAKENHI-PROJECT-25291011
[Presentation] 先端放射光を用いたチャネル・トランスポーターの高分解能構造解析と分子機構の解明2015
- Author(s)
  石谷隆一郎
- Organizer
  日本放射光学会
- Place of Presentation
  草津市，滋賀
- Year and Date
  2015-01-11
- Invited
- Data Source
  KAKENHI-PLANNED-22117007
[Presentation] Molecular Mechanisms of Membrane Transporters2015
- Author(s)
  Ryuichiro Ishitani
- Organizer
  The 13th Conference of the Asian Crystallographic Association
- Place of Presentation
  Science City, Kolkata, India
- Year and Date
  2015-12-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291011
[Presentation] シグナル伝達にかかわる因子Autotaxinの構造ベース創薬2014
- Author(s)
  石谷隆一郎
- Organizer
  日本薬学会
- Place of Presentation
  熊本大学（熊本県）
- Invited
- Data Source
  KAKENHI-PROJECT-25291011
[Presentation] 炎症応答に関わる因子の構造生物学　Cyclic GMP-AMP合成酵素の結晶構造2014
- Author(s)
  石谷隆一郎
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都市左京区，京都
- Year and Date
  2014-10-16
- Invited
- Data Source
  KAKENHI-PLANNED-22117007
[Presentation] Crystal structure of YidC reveals a membrane protein insertion mechanism2014
- Author(s)
  Ryuichiro Ishitani
- Organizer
  Gordon Research Conference on Ligand recognition & molecular gating
- Place of Presentation
  Ventura CA, USA
- Data Source
  KAKENHI-PROJECT-25291011
[Presentation] 炎症応答に関わる因子とその機能をモデュレートする化合物の構造生物学　― Cyclic GMP-AMP合成酵素の結晶構造 ―2014
- Author(s)
  石谷隆一郎
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜会議センター
- Year and Date
  2014-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-25291011
[Presentation] Crystal structure of YidC reveals a membrane protein insertion mechanism2014
- Author(s)
  Ryuichiro Ishitani
- Organizer
  Gordon Research Conference on Ligand recognition & molecular gating
- Place of Presentation
  Ventura CA, USA
- Data Source
  KAKENHI-PLANNED-22117007
[Presentation] Crystal structure of channelrhodopsin ― a light-gated cation channel ―2014
- Author(s)
  石谷隆一郎
- Organizer
  16th International Congress on Photobiology
- Place of Presentation
  Universidad Nacional de Cordoba, Cordoba, Argentina
- Year and Date
  2014-09-08
- Invited
- Data Source
  KAKENHI-PROJECT-25291011
[Presentation] 炎症応答に関わる因子とその機能をモデュレートする化合物の構造生物学　― Cyclic GMP-AMP合成酵素の結晶構造 ―2014
- Author(s)
  石谷隆一郎
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜市，神奈川
- Year and Date
  2014-11-25
- Invited
- Data Source
  KAKENHI-PLANNED-22117007
[Presentation] Crystal structure of channelrhodopsin ― a light-gated cation channel ―2014
- Author(s)
  石谷隆一郎
- Organizer
  16th International Congress on Photobiology
- Place of Presentation
  Universidad Nacional de Cordoba,Argentina
- Year and Date
  2014-09-08
- Invited
- Data Source
  KAKENHI-PLANNED-22117007
[Presentation] 炎症応答に関わる因子の構造生物学　Cyclic GMP-AMP合成酵素の結晶構造2014
- Author(s)
  石谷隆一郎
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-16
- Invited
- Data Source
  KAKENHI-PROJECT-25291011
[Presentation] シグナル伝達にかかわる因子Autotaxinの構造ベース創薬2014
- Author(s)
  石谷隆一郎
- Organizer
  日本薬学会
- Place of Presentation
  熊本市、熊本県
- Invited
- Data Source
  KAKENHI-PLANNED-22117007
[Presentation] 最先端のマイクロビームラインと計算機シミュレーションを用いた膜輸送体の構造生物学2013
- Author(s)
  石谷隆一郎
- Organizer
  蛋白質科学会
- Place of Presentation
  鳥取市、鳥取県
- Invited
- Data Source
  KAKENHI-PLANNED-22117007
[Presentation] Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1α complex2013
- Author(s)
  Ryuichiro Ishitani
- Organizer
  EMBO Conference "Eukaryotic RNA Turnover: From Structural Insights to Diseases"
- Place of Presentation
  Strasbourg, France
- Data Source
  KAKENHI-PLANNED-22117007
[Presentation] Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1α complex2013
- Author(s)
  Ryuichiro Ishitani
- Organizer
  EMBO Conference "Eukaryotic RNA Turnover: From Structural Insights to Diseases"
- Place of Presentation
  Strasbourg, France
- Data Source
  KAKENHI-PROJECT-25291011
[Presentation] 最先端のマイクロビームラインと計算機シミュレーションを用いた膜輸送体の構造生物学2013
- Author(s)
  石谷隆一郎
- Organizer
  蛋白質科学会
- Place of Presentation
  とりぎん文化会館（鳥取県）
- Invited
- Data Source
  KAKENHI-PROJECT-25291011
[Presentation] Structural basis forH+-coupled symport mechanism by POT2012
- Author(s)
  石谷隆一郎
- Organizer
  GRCon Membrane Transport Proteins
- Place of Presentation
  Les Diablerets Conference Center, Les Diablerets, Switzerland
- Data Source
  KAKENHI-PROJECT-22687007
[Presentation] Structural basis for H+-coupled symport mechanism by POT2012
- Author(s)
  石谷隆一郎
- Organizer
  GRC on Membrane Transport Proteins
- Place of Presentation
  Les Diablerets Conference Center, Les Diablerets, Switzerland
- Data Source
  KAKENHI-PROJECT-22687007
[Presentation] Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1α complex2012
- Author(s)
  石谷隆一郎
- Organizer
  XXIV tRNA Conference
- Place of Presentation
  Olmue, Chile
- Data Source
  KAKENHI-PROJECT-22687007
[Presentation] 結晶構造解析と分子動力学シミュレーションから調べるタンパク質のダイナミクス2012
- Author(s)
  石谷隆一郎
- Organizer
  JSIAM2012
- Place of Presentation
  稚内
- Year and Date
  2012-08-30
- Data Source
  KAKENHI-PROJECT-22687007
[Presentation] Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition2011
- Author(s)
  石谷隆一郎
- Organizer
  分子生物学会年会
- Place of Presentation
  パシフィコ横浜(招待講演)
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22687007
[Presentation] 古細菌由来Pelota・EF1α・GTP複合体によるmRNA品質管理機構の構造基盤2010
- Author(s)
  石谷隆一郎
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22687007
[Presentation] Structural analysis of bacterial Sec translocon machinery2010
- Author(s)
  Tsukazaki T, (他2名), Ishitani R, (他6名), Nureki O
- Organizer
  Gordon Research Conference(Protein Transport Across Cell Membranes)
- Place of Presentation
  米国テキサス州ヒューストン
- Year and Date
  2010-03-11
- Data Source
  KAKENHI-PUBLICLY-21023005
[Presentation] 古細菌由来Pelota・EF1α・GTP複合体によるmRNA品質管理機構の構造基盤2010
- Author(s)
  石谷隆一郎
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PLANNED-22117007
[]
[]

1. NUREKI Osamu (10272460)

# of Collaborated Projects: 4 results

# of Collaborated Products: 54 results
2. TAKEKAWA Mutsuhiro (30322332)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. INOUE Jun-ichiro (70176428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. YAMAOKA Shoji (90263160)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAKAHASHI Masahide (40183446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TOKUNAGA Fuminori (00212069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. ICHIKAWA Kazuhisa (20343626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OYAMA Masaaki (30422398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 石谷隆一郎 (30401186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 塚崎智也 (80436716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 上野匡 (60462660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 伊藤耕一 (10262073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. MATURANA ANDRES (10452004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 加藤英明 (80805961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NISHIMASU Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
16. HAYASHI Shigehiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. FUJIWARA Yuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. OTANI Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. OHGAKI Ryuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. NAGATOISHI Satoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. FUJIHARA Yoshitaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 広瀬豊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 山中章弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 杉田有治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 青木淳賢

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 神取秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 東雅大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 宮地孝明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 嶋田一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
30. 村上正晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 塩見春彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 中村義一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 近藤侑貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. HIPOLITO CHRISTOPHER

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
35. 関元昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 大澤匡範

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 塩見美喜子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 津本浩平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 佐藤衛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. HIPOLITO CHRIS

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHITANI RYUICHIRO 石谷 隆一郎

ISHITANI Ryuichiro 石谷 隆一郎

Research Projects

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Co-Researchers

深層学習と自動実験による酵素創出技術の高度化Principal Investigator

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タンパク質機能解析と改変に資する蛋白質・化合物複合体の立体構造予測法の構築Principal Investigator

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Structural biology of membrane transporters involved in the efflux mechanism of organic moleculesPrincipal Investigator

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Elucidation of MAPK signaling pathways and biological processes based on mathematical science

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Molecular mechanism of membrane proteins regulated by physical stimuli

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Structural biology of multidrug transportersPrincipal Investigator

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Regulation of Signal Transduction by Post-translational Modifications and Its Pathogenic Dysregulation

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Structural basis for protein posttranscriptional modifications and cellular signalingPrincipal Investigator

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Structural biology of secondary active transportersPrincipal Investigator

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分子モーターSecA ATPaseによるタンパク質膜透過機構の構造機能相関Principal Investigator

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Structural basis for carcinogenesis and cancer metastasis by oncogene products

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[Book] 酵素利用技術大系-基礎・解析から改変・高機能化・産業利用まで-(1章1節2)2010

Author(s)

Total Pages

Publisher

Data Source

[Book] 酵素利用技術大系-基礎・解析から改変・高機能化・産業利用まで-(1章1節2)2010

Author(s)

Total Pages

Publisher

ISHITANI RYUICHIRO 石谷隆一郎

ISHITANI Ryuichiro 石谷隆一郎