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NIKI Takeshi  仁木 剛史

ORCIDConnect your ORCID iD *help
… Alternative Names

仁木 剛史  ニキ タケシ

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Researcher Number 90377193
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2013 – 2014: 北海道大学, (連合)農学研究科(研究院), 准教授
2010 – 2011: 北海道大学, 大学院・農学研究院, 准教授
2005 – 2006: 新潟大学, 医歯学系, 助手
Review Section/Research Field
Principal Investigator
Neurochemistry/Neuropharmacology / Neurology
Except Principal Investigator
General pharmacology
Keywords
Principal Investigator
パーキンソン病 / DJ-1 / 酸化ストレス / Nrf2 / PTEN / ジスルフィド結合 / PARK7 / 活性酸素 / 神経分子病態学
Except Principal Investigator
中枢摂食制御 … More / 摂食中枢 / 視床下部 / 遺伝子発現 / ニューロペプチドY / 摂食関連ペプチド / 中核摂食制御 Less
  • Research Projects

    (3 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (3 People)
  •  パーキンソン病関連因子DJ-1の還元による新規機能回復ならびに酸化抑制薬の開発Principal Investigator

    • Principal Investigator
      仁木 剛史
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Hokkaido University
  •  Antioxidative defense mechanism of DJ-1, parkinson's disease related genePrincipal Investigator

    • Principal Investigator
      NIKI Takeshi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Hokkaido University
  •  RNAiを用いた摂食関連遺伝子の機能ターゲッティング法の開発

    • Principal Investigator
      樋口 宗史
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Niigata University

All 2013 2012 2011 2010 2007 2006

All Journal Article Presentation

  • [Journal Article] Neuroprotective Function of DJ-1 against Parkinson's Disease2013

    • Author(s)
      Ariga H. Takahashi-Niki K, Kato I, Maita H, Niki T,, Iguchi-Ariga SM
    • Journal Title

      SM Oxidative Medicine and Cellular Longevity

      Volume: 683920 Pages: 683920-683920

    • DOI

      10.1155/2013/683920

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790970, KAKENHI-PROJECT-24650191, KAKENHI-PROJECT-25430059, KAKENHI-PROJECT-25830071
  • [Journal Article] Identification of DJ-1-associated regions on human genes from SH-SY5Y cells using chromatin immunoprecipitation sequence technique.2013

    • Author(s)
      Yamane T, Sugimoto N, Maita H, Watanabe, K, Takahashi-Niki K, Maita C, Kato-Ose I, Ishikawa S, Gao J, Kitaura H, Niki T, Iguchi-Ariga S.M.M. Ariga H.
    • Journal Title

      Molecular Biology

      Volume: 3 Issue: 01

    • DOI

      10.4172/2168-9547.1000115

    • NAID

      120005646334

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25430059
  • [Journal Article] Identification of the recognition sequence and target proteins for DJ-1 protease2013

    • Author(s)
      Mitsugi H., Niki T., Takahashi-Niki K, Tanimura K., Yoshizawa-Kumagaye K, Tsunemi M.,Iguchi-Ariga SM, Ariga H.
    • Journal Title

      FEBS Letters

      Volume: 587(16) Issue: 16 Pages: 2493-9

    • DOI

      10.1016/j.febslet.2013.06.032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790970, KAKENHI-PROJECT-25430059
  • [Journal Article] DJ-1 cooperates with PYCR1 in cell protection against oxidative stress.2013

    • Author(s)
      Yasuda, T.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 436 Issue: 2 Pages: 289-294

    • DOI

      10.1016/j.bbrc.2013.05.095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24650191, KAKENHI-PROJECT-25430059
  • [Journal Article] Stimulation of vesicular monoamine transporter 2 activity by DJ-1 in SH-SY5Y cells Shizuma Ishikawa2012

    • Author(s)
      Yuki Tanaka, Kazuko Takahashi-Niki, Takeshi Niki, Hiroyoshi Arigab, Sanae M. M. Iguchi-Ariga
    • Journal Title

      Biochem. Biochemical and Biophysical Research

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790809
  • [Journal Article] A novel signaling pathway mediated by the nuclear targeting of C-terminal fragments of mammalian Patched 12011

    • Author(s)
      Kagawa, H., Shino, Y., Kobayashi, D., Demizu, S., Shimada, M., Ariga, H., Kawahara, H.
    • Journal Title

      PLoS ONE

      Volume: 6 Issue: 51 Pages: 39718-39731

    • DOI

      10.1074/jbc.m110.137034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014, KAKENHI-PROJECT-22790809
  • [Journal Article] Potentiation by neuropeptide Y of histamine H_1 receptor-mediated contraction in rat blood vessels.2007

    • Author(s)
      Piao H., Nagai S., Tsurumaki T., Niki T., Higuchi H.
    • Journal Title

      Vascul. Pharmacol. 46

      Pages: 260-270

    • Data Source
      KAKENHI-PROJECT-17659071
  • [Journal Article] NPY-Y5受容体ノックアウトマウスの摂食ペプチド発現の制御と摂食2006

    • Author(s)
      樋口 宗史, 山口 剛, 仁木 剛史
    • Journal Title

      日薬理誌 127

      Pages: 92-96

    • NAID

      10017495235

    • Data Source
      KAKENHI-PROJECT-17659071
  • [Presentation] DJ-1とその結合タンパク質の相互作用に対する酸化ストレスの影響2013

    • Author(s)
      仁木 剛史、仁木(高橋) 加寿子、 遠藤 仁郎、中川 翔太、有賀 寛芳、有賀(井口) 早苗
    • Organizer
      日本生化学会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-25430059
  • [Presentation] Oxidative stress-response by DJ-1 and its binding compounds2012

    • Author(s)
      Niki, T., Takahashi-Niki, K., Okamoto, A., Endo, J., Ariga, H., Iguchi-Ariga, S. M. M.
    • Organizer
      The 41th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2012-11-12
    • Data Source
      KAKENHI-PROJECT-22790809
  • [Presentation] Oxidative stress-response by DJ-1 and its binding compounas2011

    • Author(s)
      仁木剛史
    • Organizer
      Neuroscience 2011
    • Place of Presentation
      Walter E.Washington Convention Center(アメリカワシントンDC)
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-22790809
  • [Presentation] DJ-1の抗酸化ストレスセンサーとしての役割2011

    • Author(s)
      仁木(高橋)加寿子、仁木剛史、辻美咲、北浦廣剛、有賀(井口)早苗、有賀寛芳
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-22790809
  • [Presentation] パーキンソン病原因遺伝子産物DJ-1とその結合化合物による酸化ストレス誘導Nrf2転写活性化能に対する影響2011

    • Author(s)
      仁木剛史、仁木(高橋)加寿子、岡本麻美、遠藤仁朗、瀬在和哉、有賀寛芳、有賀(井口)早苗
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-22790809
  • [Presentation] バーキンソン病原因遺伝子産物DJ-1とその結合化合物による酸化ストレス誘導Nrf2転写活性化能に対する影響2011

    • Author(s)
      仁木剛史
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-22790809
  • [Presentation] パーキンソン病原因遺伝子DJ-1の抗酸化ストレス機能の解析2010

    • Author(s)
      仁木加寿子、仁木剛史、有賀(井口)早苗、有賀寛芳
    • Organizer
      BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-22790809
  • [Presentation] パーキンソン病原因遺伝子産物DJ-1とその結合化合物による酸化ストレス応答2010

    • Author(s)
      仁木剛史、仁木(高橋)加寿子、遠藤仁郎、瀬在和哉、岡本麻美、有賀寛芳、有賀(井口)早苗
    • Organizer
      BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会合同大会)
    • Place of Presentation
      神戸)
    • Data Source
      KAKENHI-PROJECT-22790809
  • [Presentation] パーキンソン病原因遺伝子産物DJ-1とその結合化合物による酸化ストレス応答2010

    • Author(s)
      仁木剛史
    • Organizer
      第33回日本分子生物学会年会・第88回日本生化学会大会 合同大会
    • Place of Presentation
      兵庫県神戸市中央区神戸国際展示場
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22790809
  • 1.  NIKI Kazuko (50447645)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 2.  樋口 宗史 (30150337)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  有賀 寛芳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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