Kihira Yoshitaka 木平孝高

… Alternative Names

木平孝高キヒラヨシタカ

KIHIRA Yoshitaka 木平孝高

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Researcher Number	90377276
Affiliation (Current)	2025: 福山大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2023: 福山大学, 薬学部, 准教授 2016 – 2018: 福山大学, 薬学部, 講師 2017: 徳島大学, 大学院医歯薬学研究部, 助教 2015: 徳島大学, 大学院医歯薬学研究部, 助教 2011 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 助教
Review Section/Research Field	Principal Investigator Pharmacology in pharmacy / Basic Section 53040:Nephrology-related / Biological pharmacy Except Principal Investigator Eating habits / General pharmacology
Keywords	Principal Investigator 低酸素誘導因子 / 糖尿病 / 肥満 / 脂肪細胞 / リモデリング / アポトーシス / 細胞死 / グルタチオン分解酵素 / 腎虚血再灌流障害 / 薬理学 … More / 脱共役タンパク質 / ベージュ脂肪細胞 / 脂質代謝 / Lipin1 / 低酸素 / lipid / hypoxia-inducible factor / adipocyte / obesity / hypoxia / 炎症 / 脂肪 / ノックアウトマウス / 塩基性線維芽細胞増殖因子 / インスリン / GLP-1 / アディポネクチン / 塩基性繊維芽細胞増殖因子 … More Except Principal Investigator AMPK / ケルセチン / 薬理学 / 栄養学 / エピゲノム解析 / エピゲノム修飾 / AMP kinase / グルカゴン / エピゲノム / 硝酸 / 亜硝酸 / 脂質代謝 / 糖代謝 / 亜硝酸塩 Less

腎虚血再灌流障害におけるグルタチオン分解酵素を介したアポトーシス制御の役割Principal Investigator
- Principal Investigator
  
  木平孝高
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Fukuyama University
Anti-diabetic effects of an inhibitor of Hypoxia-inducible facotr via induction of adiponectin highly expressing beige adipocytesPrincipal Investigator
- Principal Investigator
  
  KIHIRA Yoshitaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Fukuyama University
Physiological role of dietary nitrite
- Principal Investigator
  
  TAMAKI Toshiaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits
- Research Institution
  The University of Tokushima
The effects of lipid metabolism alteration induced by hypoxia-inducible factor on glucagon-like peptide secretionPrincipal Investigator
- Principal Investigator
  
  KIHIRA Yoshitaka
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  The University of Tokushima
Activation mechanisms of AMPK by nitrite
- Principal Investigator
  
  TSUCHIYA Koichiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokushima
The role of basic fibroblast growth factor in regulation of metabolism of adipocytePrincipal Investigator
- Principal Investigator
  
  KIHIRA Yoshitaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokushima

All 2023 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Signaling pathways upregulating glutathione‑specific γ‑glutamylcyclotransferase 1 by 3‑(5'‑hydroxymethyl‑2'‑furyl)‑1‑benzylindazole.2023
- Author(s)
  Kihira Y, Fujimura Y, Tomita S, Sato E.
- Journal Title
  
  Mol Med Rep
  
  Volume: 28 Issue: 5 Pages: 216-223
- DOI
  10.3892/mmr.2023.13103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06365, KAKENHI-PROJECT-23K07711
[Journal Article] Development of a novel aortic dissection mouse model and evaluation of drug efficacy using in-vivo assays and database analyses2019
- Author(s)
  Izawa-Ishizawa Yuki、Imanishi Masaki、Zamami Yoshito、Toya Hiroki、Nagao Tomoko、Morishita Marin、Tsuneyama Koichi、Horinouchi Yuya、Kihira Yoshitaka、Takechi Kenshi、Ikeda Yasumasa、Tsuchiya Koichiro、Yoshizumi Masanori、Tamaki Toshiaki、Ishizawa Keisuke
- Journal Title
  
  Journal of Hypertension
  
  Volume: 37 Issue: 1 Pages: 73-83
- DOI
  10.1097/hjh.0000000000001898
- NAID
  120006627861
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06686, KAKENHI-PROJECT-18K07069, KAKENHI-PROJECT-18K08480, KAKENHI-PROJECT-18K14983, KAKENHI-PROJECT-16K08272, KAKENHI-PROJECT-16K08549, KAKENHI-PROJECT-18K14920
[Journal Article] Iron suppresses erythropoietin expression via oxidative stress-dependent hypoxia-inducible factor-2 alpha inactivation.2017
- Author(s)
  Oshima K, Ikeda Y, Horinouchi Y, Watanabe H, Hamano H, Kihira Y, Kishi S, Izawa-Ishizawa Y, Miyamoto L, Hirayama T, Nagasawa H, Ishizawa K, Tsuchiya K, Tamaki T
- Journal Title
  
  Laboratory Investigation.
  
  Volume: 印刷中 Issue: 5 Pages: 555-566
- DOI
  10.1038/labinvest.2017.11
- NAID
  120006763916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16603, KAKENHI-PROJECT-16K08272, KAKENHI-PROJECT-16K08549, KAKENHI-PROJECT-15K01716
[Journal Article] Iron-induced skeletal muscle atrophy involves an Akt-forkhead box O3-E3 ubiquitin ligase-dependent pathway.2016
- Author(s)
  Yasumasa Ikeda, Mizuki Imao, Akiho Satoh, Hiroaki Watanabe, Hirofumi Hamano, Yuya Horinouchi, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Licht Miyamoto, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
- Journal Title
  
  Journal of Trace Elements in Medicine and Biology
  
  Volume: 35 Pages: 66-76
- DOI
  10.1016/j.jtemb.2016.01.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860172, KAKENHI-PROJECT-15H02898, KAKENHI-PROJECT-15K01716, KAKENHI-PROJECT-15K07967, KAKENHI-PROJECT-16K08272, KAKENHI-PROJECT-16K08549
[Journal Article] Angiotensin II alters the expression of duodenal iron transporters, hepatic hepcidin, and body iron distribution in mice2015
- Author(s)
  Soichiro Tajima, Yasumasa Ikeda, Hideaki Enomoto, Imao Mizuki, Yuya Horinouchi, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Rihito Miyamoto, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki
- Journal Title
  
  European Journal of Nutrition
  
  Volume: 印刷中 Issue: 5 Pages: 709-719
- DOI
  10.1007/s00394-014-0749-1
- NAID
  120006732013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25750044, KAKENHI-PROJECT-26870409, KAKENHI-PROJECT-15K01716, KAKENHI-PROJECT-15K07967, KAKENHI-PROJECT-15H02898
[Journal Article] Bilirubin exerts pro-angiogenic property through Akt-eNOS-dependent pathway.2015
- Author(s)
  Ikeda Y, Hamano H, Satoh A, Horinouchi Y, Izawa-Ishizawa Y, Kihira Y, Ishizawa K, Aihara K, Tsuchiya K, Tamaki T
- Journal Title
  
  Hypertens Res.
  
  Volume: 38 Issue: 1 Pages: 733-740
- DOI
  10.1038/hr.2015.118
- NAID
  120006763917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02898
[Journal Article] Bilirubin exerts pro-angiogenic effects through an Akt-eNOS-dependent pathway2015
- Author(s)
  Yasumasa Ikeda, Hamano Hirofumi, Satoh Akiho, Horinouchi Yuya, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Keisuke Ishizawa, Ken-ichi Aihara, Koichiro Tsuchiya and Toshiaki Tamaki
- Journal Title
  
  Hypertension Research
  
  Volume: 38(11) Issue: 11 Pages: 733-740
- DOI
  10.1038/hr.2015.74
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01716, KAKENHI-PROJECT-15K07967, KAKENHI-PROJECT-25461389, KAKENHI-PROJECT-26860172, KAKENHI-PROJECT-26870409
[Journal Article] A Long-Term High-Fat Diet Changes Iron Distribution in the Body, Increasing Iron Accumulation Specifically in the Mouse Spleen2015
- Author(s)
  Noriko Yamano, Yasumasa Ikeda, Minoru Sakama, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Keisuke Ishizawa, Licht Miyamoto, Shuhei Tomita, Koichiro Tsuchiya, Toshiaki Tamaki
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 61 Issue: 1 Pages: 20-27
- DOI
  10.3177/jnsv.61.20
- NAID
  130005070829
- ISSN
  0301-4800, 1881-7742
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07967, KAKENHI-PROJECT-15K15054, KAKENHI-PROJECT-26860172, KAKENHI-PROJECT-26870409
[Journal Article] Hypoxia Decreases Glucagon-Like Peptide-1 Secretion from the GLUTag Cell Line2015
- Author(s)
  Yoshitaka Kihira, Ariunzaya Burentogtokh, Mari Itoh, Yuki Izawa-Ishizawa, Keisuke Ishizawa, Yasumasa Ikeda, Koichiro Tsuchiya, and Toshiaki Tamaki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 38 Issue: 4 Pages: 514-521
- DOI
  10.1248/bpb.b14-00612
- NAID
  130005062264
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860172, KAKENHI-PROJECT-15K01716, KAKENHI-PROJECT-15K07967, KAKENHI-PROJECT-26870409
[Journal Article] Overexpressed HIF-2α in Endothelial Cells Promotes Vascularization and Improves Random Pattern Skin Flap Survival.2014
- Author(s)
  Morimoto A, Tomita S, Imanishi M, Shioi G, Kihira Y, Izawa-Ishizawa Y, Takaku M, Hashimoto I, Ikeda Y, Nakanishi H, Tamaki T.
- Journal Title
  
  Plast Reconstr Surg Glob Open
  
  Volume: 7 Issue: 4 Pages: e132-e132
- DOI
  10.1097/gox.0000000000000083
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24591203, KAKENHI-PROJECT-26860172, KAKENHI-PROJECT-26870409
[Journal Article] Deletion of hypoxia-inducible factor-1αin adipocytes enhances glucagon-like Peptide-1 secretion and reduces adipose tissue inflammation2014
- Author(s)
  Kihira Y, Miyake M, Hirata M, Hoshina Y, Kato K, Shirakawa H, Sakaue H, Yamano N, Izawa-Ishizawa Y, Ishizawa K, Ikeda Y, Tsuchiya K, Tamaki T, Tomita S
- Journal Title
  
  PLoS One
  
  Volume: 9(4) Pages: 93856-93856
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790089
[Journal Article] Drug development for cardiorenal disease based on oxidative stress control2014
- Author(s)
  Imanishi M, Ishizawa K, Sakurada T, Ishizawa Y, Yamano N, Kihira Y, Ikeda Y, Tsuchiya K, Tamaki T.
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 134 Pages: 715-719
- NAID
  130004427995
- Data Source
  KAKENHI-PROJECT-26870409
[Journal Article] Deletion of Hypoxia-Inducible Factor-1α in Adipocytes Enhances Glucagon-Like Peptide-1 Secretion and Reduces Adipose Tissue Inflammation2014
- Author(s)
  Yoshitaka KIHIRA, Mariko MIYAKE, Manami HIRATA, Yoji HOSHINA, Kana KATO, Hitoshi SHIRAKAWA, Hiroshi SAKAUE, Noriko YAMANO, Yuki IZAWA-ISHIZAWA, Keisuke ISHIZAWA, Yasumasa IKEDA, Koichiro TSUCHIYA, Toshiaki TAMAKI, Shuhei TOMITA
- Journal Title
  
  PLOS ONE
  
  Volume: 9 Issue: 4 Pages: e93856-e93856
- DOI
  10.1371/journal.pone.0093856
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23790089, KAKENHI-PROJECT-24590381, KAKENHI-PROJECT-24591333, KAKENHI-PROJECT-24790254, KAKENHI-PUBLICLY-25126718, KAKENHI-PROJECT-25860063, KAKENHI-PROJECT-26860172, KAKENHI-PROJECT-26870409
[Journal Article] Basic fibroblast growth factor regulates glucose metabolism through glucose transporter 1 induced by hypoxia-inducible factor-1αin adipocytes2011
- Author(s)
  Kihira Y, Yamano N, Izawa-Ishizawa Y, Ishizawa K, Ikeda Y, Tsuchiya K, Tamaki T, Tomita S
- Journal Title
  
  Int J Biochem Cell Biol
  
  Volume: 43 Issue: 11 Pages: 1602-1611
- DOI
  10.1016/j.biocel.2011.07.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590335, KAKENHI-PROJECT-22790864, KAKENHI-PROJECT-23790089, KAKENHI-PROJECT-23790298
[Journal Article] Basic fibroblast growth factor regulates glucose metabolism through glucose transporter 1 induced by hypoxia-inducible factor-1αin adipocytes2011
- Author(s)
  Kihira Y, Yamano N, Izawa-Ishizawa Y, Ishizawa K, Ikeda Y, Tsuchiya K, Tamaki T, Tomita S
- Journal Title
  
  Int J Biochem Cell Biol
  
  Volume: 43(11) Pages: 1602-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] 低酸素/再酸素化処理における尿細管細胞のCHAC1発現に対するN-acetylcysteineの影響2023
- Author(s)
  松葉春佳、斎藤優希、藤村よしの、木平孝高、佐藤英治
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K07711
[Presentation] Hypoxia-Inducible Factor-1Alpha Induces Apoptosis of Tubular Cells in Renal Ischemia-Reperfusion Injury via Regulating Glutathione-Specific Gamma-Glutamylcyclotransferase 12023
- Author(s)
  Kihira Yoshitaka, Homma Takujiro, Fujimura Yoshino, Matsunaga Shinji, Sato Eiji, Tomita Shuhei
- Organizer
  American Society of Nephrology Kidney Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07711
[Presentation] 腎虚血再灌流障害における尿細管細胞アポトーシスに対するCHAC1の役割2019
- Author(s)
  山本梨乃, 武田佳士, 藤村よしの, 木平孝高, 冨田修平, 佐藤英治
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] 高脂肪食負荷により肥満を誘発した低酸素誘導因子 -1 αへテロ欠損マウスの体重および血糖値推移2019
- Author(s)
  佐藤友美, 藤村よしの, 木平孝高, 佐藤英治
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] 内臓脂肪においてリゾホスファチジン酸は低酸素誘導因子の発現を上昇させる2019
- Author(s)
  宮本佳織, 山本芽生, 岩川まどか, 藤村よしの, 木平孝高, 佐藤英治
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] Glutathione Specific Gamma-Glutamylcyclotransferase 1, CHAC1 regulates Bcl-2 expression in acute kidney injury2019
- Author(s)
  Kihira Y., Yamaguchi T., Fujimura Y., Sato E., Tamaki T., Tomita S
- Organizer
  第92回薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] 腎虚血再灌流障害時に尿細管細胞において低酸素誘導因子がpaired box gene 2の発現を誘導する2018
- Author(s)
  武田佳士、山本梨乃、高木明日香、木平孝高、藤村よしの、佐藤英治
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] 脂肪細胞におけるリゾホスファチジン酸による低酸素誘導因子の調節2018
- Author(s)
  山本芽生、藤原美穂、藤村よしの、木平孝高、佐藤英治
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] エルネオパ２号輸液中に混注されたインスリンの含量変化に関する検討2017
- Author(s)
  佐藤英治、前田祥汰、藤村よしの、木平孝高、井上裕文、山下貴弘、熊谷岳文、鶴田泰人、吉富博則
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター (宮城県、仙台市)
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] YC-1は尿細管上皮細胞においてグルタチオン分解酵素CHAC1の発現を誘導する2017
- Author(s)
  藤村よしの、木平孝高、吉富博則、佐藤英治
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター (宮城県、仙台市)
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] ヒト腎尿細管細胞におけるCHAC1制御機構の解明2017
- Author(s)
  池田政聡、木平孝高、藤村よしの、佐藤英治
- Organizer
  第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] 福山大学薬学部におけるコミュニケーション交流学習の取り組み～役立ち感・自己肯定感を育み、ホスピタリティを涵養するために～2016
- Author(s)
  松岡浩史、井上裕文、岡村信幸、渡邊正知、五郎丸剛、前原昭次、道原明宏、田中哲郎、大西正俊、小嶋英二朗、井上敦子、田村豊、坂根洋、長崎信浩、瀬尾誠、藤岡晴人、広瀬雅一、木平孝高、高山健人、伊達有子、藤井早由利、吉富博則、鶴田泰人
- Organizer
  第1回日本薬学教育学会
- Place of Presentation
  京都薬科大学 (京都府、京都市)
- Year and Date
  2016-08-27
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] 電位依存性カリウムチャネルKv2.2は腎虚血再灌流障害の軽減に関与する2016
- Author(s)
  太田和馬、木平孝高、岸渕麗奈、石澤有紀、池田康将、石澤啓介、土屋浩一郎、冨田修平、玉置俊晃
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川・横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] HIF-1aはアポトーシス制御因子Bcl-2及びCHAC1の発現制御を介して腎虚血再灌流障害からの回復に関与する2016
- Author(s)
  岸渕麗奈、木平孝高、山口邦久、石澤有紀、池田康将、石澤啓介、冨田修平、土屋浩一郎、玉置俊晃
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] Topical Application of Nitrosonifedipine, a Novel Free Radical Scavenger, Ameliorate the Ischemic Skin Flap Necrosis2016
- Author(s)
  Yutaka Fukunaga, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Yasumasa Ikeda, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki, Ichiro Hashimoto
- Organizer
  Plastic Surgery THE MEETING 2016
- Place of Presentation
  Los Angeles Convention Center (Los Angeles, California, USA)
- Year and Date
  2016-09-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] 鉄は低酸素誘導因子を抑制してエリスロポエチン発現を低下させる2016
- Author(s)
  池田康将、大島啓亮、石澤有紀、木平孝高、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川県、横浜市)
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] エルネオパ2号輸液中に混注された薬剤の安定性に関する検討2016
- Author(s)
  中司絢子、井上裕文、久保沙織、楢原奈穂子、佐藤英治、木平孝高、藤村よしの、山下貴弘、熊谷岳文、吉富博則、伊達有子、小島英二郎、鶴屋泰人
- Organizer
  第55回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  就実大学 (岡山県、岡山市)
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] Disruption of hypoxia-inducible factor-1a deteriorates renal ischemia-reperfusion injury through dysregulation of Kv2.2-induced apoptosis in tubules.2016
- Author(s)
  Kazuma Ota, Yoshitaka Kihira, Reina Kishibuchi, Yuki Izawa-Ishizawa, Yuya Horinouchi, Yasumasa Ikeda, Toshiaki Tamaki
- Organizer
  ASN KIDNEY WEEK 2016
- Place of Presentation
  McCormick Place (Chicago, Illinois, USA)
- Year and Date
  2016-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08272
[Presentation] ケルセチン代謝物Q3GAによる血管内皮細胞保護効果の検討2016
- Author(s)
  斎藤尚子、石澤有紀、細岡真由子、木平孝高、今西正樹、座間味義人、池田康将、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H02898
[Presentation] Bilirubin Promotes Ischemic-Induced Revascularization through Akt-eNOS Pathway2015
- Author(s)
  Yasumasa Ikeda, Yusuke Kanai, Yuya Horinouchi, Yuki Izawa-Ishizawa, Yoxhitaka Kihira, Licht Miyamoto, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
- Organizer
  第79回　日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府・大阪市）
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] 慢性腎臓病におけるヘプシジン制御メカニズムの検討2015
- Author(s)
  池田康将、濱野裕章、渡邉大晃、堀ノ内裕也、石澤有紀、木平孝高、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第25回日本循環薬理学会
- Place of Presentation
  東大寺総合文化センター金鐘ホール（奈良県・奈良市）
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] 大動脈解離発症における内皮障害の関与2015
- Author(s)
  斎藤尚子、石澤有紀、石澤啓介、戸谷紘基、今西正樹、鍵本優有、細岡真由子、木平孝高、池田康将、土屋浩一郎、玉置俊晃
- Organizer
  第25回日本循環薬理学会
- Place of Presentation
  東大寺総合文化センター金鐘ホール（奈良県・奈良市）
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] YC1 increased adiponectin expression in 3T3-L1 adipocytes2015
- Author(s)
  Burentogtokh Ariunzaya、木平孝高、石澤有紀、池田康将、土屋浩一郎、玉置俊晃
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2015
- Place of Presentation
  東京大学（東京都・文京区）
- Year and Date
  2015-08-29
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] 悪性脳卒中易発性高血圧自然発症ラットの神経症状に対するニトロソニフェジピンの効果2015
- Author(s)
  高田真衣、石澤啓介、田渕正樹、石澤有紀、宮本理人、木平孝高、池田康将、玉置俊晃、土屋浩一郎
- Organizer
  第54回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  高知市文化プラザ　かるぽーと（高知県・高知市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] Bilirubin Enhances Ischimia-induced Angiogenesis Through Akt-eNOS-Dependent Signaling Pathway2015
- Author(s)
  Yasumasa Ikeda, Hirofumi Hamano, Yuya Horinouchi, Yuki Izawa-Ishizawa, Yoshitaka Kihira, Keisuke Ishizawa, Koichiro Tsuchiya, Toshiaki Tamaki
- Organizer
  American Heart Association Scientific Sessions 2015
- Place of Presentation
  Orange County Convention Center, Orlando, Florida（USA）
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] 鉄蓄積によって引き起こされる骨格筋萎縮のメカニズム2015
- Author(s)
  今尾瑞季、池田康将、佐藤明穂、濱野裕章、堀ノ内裕也、宮本理人、木平孝高、石澤有紀、石澤啓介、玉置俊晃、土屋浩一郎
- Organizer
  第54回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  高知市文化プラザ　かるぽーと（高知県・高知市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] Novel aortic dissection model by pharmacologically-induced endothelial dysfunction2015
- Author(s)
  Yuki Izawa-Ishizawa, Keisuke Ishizawa, Hiroki Toya, Yoshitaka Kihira, Yasumasa Ikeda, Koichiro Tsuchiya, Toshiaki Tamaki
- Organizer
  ISA2015 7th International Symposium on Atherosclerosis
- Place of Presentation
  Amsterdam RAI Congress Centre, Amsterdam（Netherland）
- Year and Date
  2015-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] ニトロソニフェジピンは悪性脳卒中易発性高血圧自然発症ラットの生命予後を改善する2015
- Author(s)
  石澤有紀、石澤啓介、高田真衣、田渕正樹、今西正樹、木平孝高、池田康将、土屋浩一郎、玉置俊晃
- Organizer
  第25回日本循環薬理学会
- Place of Presentation
  東大寺総合文化センター金鐘ホール（奈良県・奈良市）
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] 大動脈解離発症における内皮障害の関与の検討2015
- Author(s)
  戸谷紘基、石澤啓介、石澤有紀、細岡真由子、鍵本優有、斎藤尚子、宮本理人、木平孝高、池田康将、玉置俊晃、土屋浩一郎
- Organizer
  日本病院薬剤師会第54回日本薬学会・日本薬剤師会・中国四国支部学術大会
- Place of Presentation
  高知市文化プラザ　かるぽーと（高知県・高知市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] 鉄欠乏は骨格筋量減少の原因となる2015
- Author(s)
  池田康将、佐藤明穂、堀ノ内裕也、石澤有紀、木平孝高、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第39回日本鉄バイオサイエンス学会学術集会
- Place of Presentation
  岡山コンベンションセンター（岡山県・岡山市）
- Year and Date
  2015-08-29
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] 慢性腎不全における尿毒素によるヘプシジン制御機構2015
- Author(s)
  濱野裕章、池田康将、堀ノ内裕也、佐藤明穂、渡邉大晃、大島啓亮、石澤有紀、木平孝高、石澤啓介、土屋浩一郎、玉置俊晃
- Organizer
  第128回　日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府・大阪市）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] 血管石灰化シグナルにおけるRhoキナーゼおよびサイクロフィリンAの関与2015
- Author(s)
  石澤有紀, 石澤啓介, 大越瑞穂, 土肥紗希子, 木平孝高, 池田康将, 玉置俊晃
- Organizer
  第47回日本動脈硬化学会総会・学術集会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] 高脂肪食誘発肥満に対する脂肪特異的低酸素誘導因子欠損の影響2014
- Author(s)
  木平孝高, 石澤有紀, 池田康将, 土屋浩一郎, 玉置俊晃, 冨田修平
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島大学大塚講堂（徳島県・徳島市）
- Year and Date
  2014-11-20
- Data Source
  KAKENHI-PROJECT-26870409
[Presentation] 腸管L細胞のグルカゴン様ペプチド-1分泌に対する低酸素の影響2014
- Author(s)
  木平孝高, BURENTOGTOKH Ariunzaya,伊藤麻里,山野範子,石澤有紀,石澤啓介,池田康将,土屋浩一郎,玉置俊晃
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県,ホテル日航熊本,熊本大学黒髪キャンパス,熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] 腸管L細胞のグルカゴン様ペプチド-1分泌に対する低酸素の影響2014
- Author(s)
  木平孝高、Ariunzaya BURENTOGTOKH、伊藤麻里、山野範子、石澤有紀、石澤啓介、池田康将、土屋浩一郎、玉置俊晃
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市総合体育館（熊本）
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] 脂肪細胞特異的低酸素誘導因子欠損マウスに観察される耐糖能の改善にはglucagon-like peptide-1が関与する2013
- Author(s)
  木平孝高, et al
- Organizer
  第42回日本心脈管作動物質学会
- Place of Presentation
  奈良県立新公会堂(奈良県)
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] 肥満に伴う脂肪組織炎症に対する低酸素誘導因子の役割2013
- Author(s)
  木平孝高,冨田修平,山野範子,石澤有紀,石澤啓介,池田康将,土屋浩一郎,玉置俊晃
- Organizer
  第124回日本薬理学会近畿部会
- Place of Presentation
  京都府,京都ガーデンパレス
- Year and Date
  2013-11-01
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] 脂肪細胞特異的低酸素誘導因子欠損マウスに観察される耐糖能の改善にはglucagon-like peptide-1が関与する2013
- Author(s)
  木平孝高,冨田修平,三宅真理子,保科耀司,山野範子,石澤有紀,石澤啓介,池田康将,土屋浩一郎,玉置俊晃
- Organizer
  第42回日本心脈管作動物質学会
- Place of Presentation
  奈良県,奈良県立新公会堂
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] 脂肪細胞の低酸素誘導因子欠損による耐糖能改善メカニズムの解析2013
- Author(s)
  三宅真理子,木平孝高,冨田修平,山野範子,石澤有紀,石澤啓介,池田康将,土屋浩一郎,玉置俊晃
- Organizer
  第52回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  愛媛県,松山大学文京キャンパス
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] Secretion of glucagon-like peptide-1 from Intestinal L cell in hypoxia2013
- Author(s)
  伊藤麻里,木平孝高,山野範子,石澤有紀,石澤啓介,池田康将,土屋浩一郎,冨田修平,玉置俊晃
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡県、福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] 脂肪細胞の低酸素誘導因子欠損による耐糖能改善メカニズムの解析2013
- Author(s)
  三宅真理子、木平孝高、冨田修平、山野範子、石澤有紀，、石澤啓介、池田康将、土屋浩一郎、玉置俊晃
- Organizer
  第52回日本薬学会・日本薬剤師会・日本病院薬剤師会　中国四国支部学術大会
- Place of Presentation
  松山大学文京キャンパス（愛媛）
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] Adipocyte-specific hypoxia-inducible factor-1alpha knockout stimulated GLP-1 and insulin secretions in mice2013
- Author(s)
  保科耀司,木平孝高,冨田修平,三宅真理子,山野範子,石澤有紀,石澤啓介,池田康将,土屋浩一郎,玉置俊晃
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡県,福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] 肥満に伴う脂肪組織炎症に対する低酸素誘導因子の役割2013
- Author(s)
  木平孝高、冨田修平、山野範子、石澤有紀、石澤啓介、池田康将、土屋浩一郎、玉置俊晃
- Organizer
  第124回日本薬理学会近畿部会
- Place of Presentation
  京都ガーデンパレス（京都）
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] 脂肪細胞における低酸素誘導因子1a欠損は高脂肪食負荷による耐糖能異常の発現を抑制する2012
- Author(s)
  三宅真理子,木平孝高,平田愛美,石澤有紀,石澤啓介,池田康将,土屋浩一郎,玉置俊晃,冨田修平
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道,北海道大学札幌キャンパス
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] High fat diet-induced inflammation in adipose tissues is reduced in adipocyte-specific hypoxia-inducible factor-1a knockout mice2012
- Author(s)
  平田愛美,木平孝高,三宅真理子,石澤有紀,石澤啓介,池田康将,土屋浩一郎,玉置俊晃,冨田修平
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都府,国立京都国際会館、グランドプリンスホテル京都
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] 肥満に伴う耐糖能異常の発現に対する脂肪細胞の低酸素誘導因子の役割2012
- Author(s)
  木平孝高
- Organizer
  第41回心脈管作動物質学会
- Place of Presentation
  秋田, 秋田キャッスルホテル
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] 肥満に伴う耐糖能異常の発現に対する脂肪細胞の低酸素誘導因子の役割2012
- Author(s)
  木平孝高,三宅真理子,平田愛美,石澤有紀,石澤啓介,池田康将,土屋浩一郎,玉置俊晃,冨田修平
- Organizer
  第41回心脈管作動物質学会
- Place of Presentation
  秋田県、秋田キャッスルホテル
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] Glucose Metabolism of Adipocytes is Regulated by Basic Fibroblast Growth Factor via Hypoxia-inducible Factor-1a2011
- Author(s)
  Yamaguchi K, Kihira Y, Yamano N, Ishizawa Y, Ishizawa K, Ikeda Y, Tsuchiya K, Tomita S, Tamaki T
- Organizer
  High Blood Pressure Research Scientific Sessions 2011 Scientific Sessions
- Place of Presentation
  USA, Orlando, Fla. Walt Disney World Dolphin Resort
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] 脂肪細胞における塩基性繊維芽細胞増殖因子による低酸素誘導因子誘導とそれを介した糖輸送担体発現誘導2011
- Author(s)
  木平孝高,石澤啓介,池田康将,土屋浩一郎,冨田修平,玉置俊晃
- Organizer
  第118回日本薬理学会近畿部会
- Place of Presentation
  大阪府,千里ライフサイエンスセンター
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-23790089
[Presentation] 亜硝酸塩による腎保護作用とその機序
- Author(s)
  土屋浩一郎、宮本理人、石澤啓介、冨田洋輔、山根　萌、木平孝高、池田康将、玉置俊晃
- Organizer
  第66回日本酸化ストレス学会学術集会
- Place of Presentation
  ウィンクあいち（愛知県名古屋市）
- Data Source
  KAKENHI-PROJECT-25460332
[Presentation] ヒト腎糸球体内皮細胞における亜硝酸塩によるAMPK-eNOS活性化経路の検討
- Author(s)
  山根　萌、宮本理人、冨田洋輔、石澤啓介、池田康将、木平孝高、玉置俊晃、土屋浩一郎
- Organizer
  第25回腎とフリーラジカル研究会
- Place of Presentation
  昭和大学（東京都品川区）
- Data Source
  KAKENHI-PROJECT-25460332
[Presentation] Significance of AMPK-eNOS pathway in renal protective effects of nitrite.
- Author(s)
  Koichiro Tsuchiya, Licht Miyamoto, Megumi Yamane, Mai Kono, Yosuke Tomida, Keisuke Ishizawa, Yoshitaka Kihira, Yasumasa Ikeda, Toshiaki Tamaki
- Organizer
  5th International meeting on the role of nitrite and nitrate in physiology, pathophysiology and therapeutics
- Place of Presentation
  Pittsburgh Univ. Pittsburgh PA (USA)
- Data Source
  KAKENHI-PROJECT-25460332
[Presentation] Hypoxia decreases glucagon-like peptide-1 secretion from glutag cell lines
- Author(s)
  Ariunzaya Burentogtokh, 木平孝高, 石澤有紀, 池田康将, 土屋浩一郎, 玉置俊晃
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26870409

1. TSUCHIYA Koichiro (70301314)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. TAMAKI Toshiaki (80179879)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. IKEDA Yasumasa (60432754)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. ISHIZAWA Keisuke (60398013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 井本逸勢 (30258610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 石澤有紀 (40610192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. TAJIMA Soichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. HAMANO Hirofumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. SATO Akiho

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 富田修平

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. 堀ノ内裕也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 座間味義人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 今西正樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 武智研志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kihira Yoshitaka 木平 孝高

木平 孝高 キヒラ ヨシタカ

KIHIRA Yoshitaka 木平 孝高

Research Projects

Research Products

Co-Researchers

腎虚血再灌流障害におけるグルタチオン分解酵素を介したアポトーシス制御の役割Principal Investigator

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Anti-diabetic effects of an inhibitor of Hypoxia-inducible facotr via induction of adiponectin highly expressing beige adipocytesPrincipal Investigator

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Physiological role of dietary nitrite

Principal Investigator

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The effects of lipid metabolism alteration induced by hypoxia-inducible factor on glucagon-like peptide secretionPrincipal Investigator

Principal Investigator

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Activation mechanisms of AMPK by nitrite

Principal Investigator

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The role of basic fibroblast growth factor in regulation of metabolism of adipocytePrincipal Investigator

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Research Field

Research Institution

[Journal Article] Signaling pathways upregulating glutathione&#8209;specific γ&#8209;glutamylcyclotransferase 1 by 3&#8209;(5'&#8209;hydroxymethyl&#8209;2'&#8209;furyl)&#8209;1&#8209;benzylindazole.2023

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DOI

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[Journal Article] Development of a novel aortic dissection mouse model and evaluation of drug efficacy using in-vivo assays and database analyses2019

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NAID

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[Journal Article] Iron suppresses erythropoietin expression via oxidative stress-dependent hypoxia-inducible factor-2 alpha inactivation.2017

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NAID

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[Journal Article] Iron-induced skeletal muscle atrophy involves an Akt-forkhead box O3-E3 ubiquitin ligase-dependent pathway.2016

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[Journal Article] Angiotensin II alters the expression of duodenal iron transporters, hepatic hepcidin, and body iron distribution in mice2015

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NAID

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[Journal Article] Bilirubin exerts pro-angiogenic property through Akt-eNOS-dependent pathway.2015

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NAID

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[Journal Article] Bilirubin exerts pro-angiogenic effects through an Akt-eNOS-dependent pathway2015

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Kihira Yoshitaka 木平孝高

木平孝高キヒラヨシタカ

KIHIRA Yoshitaka 木平孝高

[Journal Article] Signaling pathways upregulating glutathione‑specific γ‑glutamylcyclotransferase 1 by 3‑(5'‑hydroxymethyl‑2'‑furyl)‑1‑benzylindazole.2023

[Presentation] 腎虚血再灌流障害における尿細管細胞アポトーシスに対するCHAC1の役割2019