Fujimoto Hajime 藤本源

Researcher Number	90378399
Other IDs
Affiliation (Current)	2025: 三重大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 三重大学, 医学系研究科, 講師
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related Except Principal Investigator Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator COVID-19 / corisin Except Principal Investigator 細菌叢 / 細胞死 / corisin / 急性肺炎 / SARS-CoV-2 / サイトカイン / 凝固制御機構 / 凝固系 … More / マウスモデル / コリシン / 急性肺障害 / COVID-19 / 線維化 / 肺癌 / 肺線維症 / 呼吸器 / マイクロバイオーム Less

COVID-19における肺傷害促進因子Corisinの検討Principal Investigator
- Principal Investigator
  
  藤本源
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Mie University
Development of a new treatment for COVID-19-related acute lung injury targeting the microbiota-derived peptide corisin
- Principal Investigator
  
  Gabazza Esteban
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Mie University
Microbiome in the Development of Lung Cancer
- Principal Investigator
  
  Kobayashi Tetsu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Mie University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Adenine Nucleotide Translocases and Cellular Senescence in Idiopathic Pulmonary Fibrosis2024
- Author(s)
  Kobayashi Tetsu、Fujimoto Hajime、D’Alessandro-Gabazza Corina N.、Yasuma Taro、Gabazza Esteban C.
- Journal Title
  
  American Journal of Respiratory Cell and Molecular Biology
  
  Volume: 70 Issue: 3 Pages: 226-226
- DOI
  10.1165/rcmb.2023-0386le
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07651
[Journal Article] Close-to-lesion transbronchial biopsy: a novel technique to improve suitability of specimens for genetic testing in patients with peripheral pulmonary lesions2023
- Author(s)
  Nishii Y, Sakaguchi T, Esumi S, Esumi M, Nakamura Y, Suzuki Y, Ito K, Fujiwara K, Yasui H, Ito A, Tarukawa T, Tsuruga T, D'Alessandro-Gabazza CN, Yasuma T, Fujimoto H, Asano F, Gabazza EC, Kobayashi T, Taguchi O, Hataji O.
- Journal Title
  
  Sci Rep.
  
  Volume: 13 Issue: 1 Pages: 14724-14724
- DOI
  10.1038/s41598-023-41726-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08203
[Journal Article] Amelioration of Pulmonary Fibrosis by Matrix Metalloproteinase-2 Overexpression.2023
- Author(s)
  Inoue R, Yasuma T, Fridman D'Alessandro V, Toda M, Ito T, Tomaru A, D'Alessandro-Gabazza CN, Tsuruga T, Okano T, Takeshita A, Nishihama K, Fujimoto H, Kobayashi T, Gabazza EC.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 24(7) Issue: 7 Pages: 6695-6695
- DOI
  10.3390/ijms24076695
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15206, KAKENHI-PROJECT-23K07651, KAKENHI-PROJECT-21K08203
[Journal Article] Epoprostenol and Treprostinil: Differential Effects on Regulatory T-Cell Generation in Patients with Pulmonary Arterial Hypertension2023
- Author(s)
  Yasuma Taro、Fujimoto Hajime、D’Alessandro-Gabazza Corina N.、Gabazza Esteban C.、Hataji Osamu、Kobayashi Tetsu
- Journal Title
  
  American Journal of Respiratory and Critical Care Medicine
  
  Volume: 208 Issue: 11 Pages: 1248-1248
- DOI
  10.1164/rccm.202308-1347le
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07651, KAKENHI-PROJECT-21K08203
[Journal Article] Prognostic Value of CXCL12 in Non-Small Cell Lung Cancer Patients Undergoing Tumor Resection2023
- Author(s)
  Kogue Yurie、Kobayashi Hiroyasu、Nakamura Yutaka、Takano Takatsugu、Furuta Chihiro、Kawano Osamu、Yasuma Taro、Nishimura Tadashi、D’Alessandro-Gabazza Corina N.、Fujimoto Hajime、Gabazza Esteban C.、Kobayashi Tetsu、Fukai Ichiro
- Journal Title
  
  Pharmaceuticals
  
  Volume: 16 Issue: 2 Pages: 255-255
- DOI
  10.3390/ph16020255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07651
[Journal Article] Elevated plasma and bile levels of corisin, a microbiota-derived proapoptotic peptide, in patients with severe acute cholangitis2023
- Author(s)
  Nishiwaki R, Imoto I, Oka S, Yasuma T, Fujimoto H, D'Alessandro-Gabazza CN, Toda M, Kobayashi T, Osamu H, Fujibe K, Nishikawa K, Hamaguchi T, Sugimasa N, Noji M, Ito Y, Takeuchi K, Cann I, Inoue Y, Kato T, Gabazza EC.
- Journal Title
  
  Gut Pathog.
  
  Volume: 15 Issue: 1 Pages: 59-59
- DOI
  10.1186/s13099-023-00587-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08203
[Journal Article] Inhibition of a Microbiota-Derived Peptide Ameliorates Established Acute Lung Injury2023
- Author(s)
  D'Alessandro Fridman V, D'Alessandro-Gabazza CN, Yasuma T, Toda M, Takeshita A, Tomaru A, Tharavecharak S, Lasisi IO, Hess RY, Nishihama K, Fujimoto H, Kobayashi T, Cann I, Gabazza EC.
- Journal Title
  
  American Journal of Pathology
  
  Volume: 23 Issue: 6 Pages: 740-754
- DOI
  10.1016/j.ajpath.2023.03.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08280, KAKENHI-PROJECT-20K08564, KAKENHI-PROJECT-21K16116, KAKENHI-PROJECT-21K16160, KAKENHI-PROJECT-23K15206, KAKENHI-PROJECT-21K08203, KAKENHI-PROJECT-21K16185
[Journal Article] Response of Lung Microbiota to Changes of Pulmonary Innate Immunity under Healthy Conditions2022
- Author(s)
  Yasuma Taro、D’Alessandro-Gabazza Corina N.、Fujimoto Hajime、Kobayashi Tetsu、Gabazza Esteban C.
- Journal Title
  
  American Journal of Respiratory and Critical Care Medicine
  
  Volume: 205 Issue: 4 Pages: 477-477
- DOI
  10.1164/rccm.202109-2187le
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08564, KAKENHI-PROJECT-21K08203
[Journal Article] Microbial Burden-associated Cytokine Storm May Explain Nonresolving Acute Respiratory Distress Syndrome in Patients with COVID-192022
- Author(s)
  Yasuma T, D'Alessandro-Gabazza CN, Kobayashi T, Gabazza EC, Fujimoto H.
- Journal Title
  
  Am J Respir Crit Care Med .
  
  Volume: 206 Issue: 9 Pages: 1182-1183
- DOI
  10.1164/rccm.202207-1266le
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08203
[Journal Article] A Microbiome-Derived Peptide Induces Apoptosis of Cells from Different Tissues2021
- Author(s)
  Saiki Haruko、Okano Yuko、Yasuma Taro、Toda Masaaki、Takeshita Atsuro、Abdel-Hamid Ahmed M.、Fridman D’Alessandro Valeria、Tsuruga Tatsuki、D’Alessandro-Gabazza Corina N.、Katayama Kan、Sugimoto Masahiko、Fujimoto Hajime、Yamanaka Keiichi、Kobayashi Tetsu、Cann Isaac、Gabazza Esteban C.
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 11 Pages: 2885-2885
- DOI
  10.3390/cells10112885
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08564, KAKENHI-PROJECT-21K08203, KAKENHI-PROJECT-21K16185
[Presentation] Corisinは肺線維症のバイオマーカーとなりうる2023
- Author(s)
  伊藤稔之、小林哲、大岩綾香、古橋一樹、鶴賀龍樹、岡野智仁、藤原拓海、都丸敦史、高橋佳紀、藤本源、Corina Gabazza、Esteban C. Gabazza
- Organizer
  第63回呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08203
[Presentation] 肺内細菌叢由来ペプチドの炎症促進作用2023
- Author(s)
  古橋一樹、小林哲、伊藤稔之、大岩綾香、鶴賀龍樹、岡野智仁、藤原拓海、都丸敦史、高橋佳紀、藤本源、Corina Gabazza、Esteban C. Gabazza
- Organizer
  第63回呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08203
[Presentation] 細菌叢由来のアポトーシス促進ペプチドの抑制は急性肺障害を改善する2023
- Author(s)
  岡野　智仁、岩中　宗一、伊藤　稔之、古橋　一樹、大岩　綾香、鶴賀　龍樹、齋木　晴子、藤原　拓海、都丸　敦史、高橋　佳紀、藤本　源、Valeria Fridman D’Alessandro、Corina Gabazza、Esteban C. Gabazza、小林　哲
- Organizer
  第63回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-23K07651
[Presentation] 細菌叢由来のアポトーシス促進ペプチドの抑制は急性肺障害を改善する2023
- Author(s)
  岡野智仁、岩中宗一、伊藤稔之、古橋一樹、大岩綾香、鶴賀龍樹、齋木晴子、藤原拓海、都丸敦史、高橋佳紀、藤本源、Valeria Fridman D'Alessandro、Corina N. D'Alessandro-Gabazza、Gabazza Esteban C、小林哲
- Organizer
  第63回呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08203
[Presentation] Corisin は肺線維症のバイオマーカーとなりうる2023
- Author(s)
  都丸　敦史、小林　哲、藤本　源、岡野　智仁、藤原　拓海、鶴賀　龍樹、大岩　綾香、伊藤　稔之、古橋　一樹、Esteban C. Gabazza、Corina Gabazza
- Organizer
  第63回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-23K07651
[Presentation] COPDにおけるマイクロバイオーム2023
- Author(s)
  藤本　源
- Organizer
  第63回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-23K07651
[Presentation] 肺内細菌叢由来ペプチドの炎症促進作用2023
- Author(s)
  古橋　一樹、小林　哲、伊藤　稔之、大岩　綾香、鶴賀　龍樹、岡野　智仁、藤原　拓海、都丸　敦史、高橋　佳紀、藤本　源、Corina Gabazza、Esteban C. Gabazza
- Organizer
  第63回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-23K07651
[Presentation] ブドウ球菌由来のアポトーシス促進ペプチドはブレオマイシン誘発肺線維症モデルにおいて慢性期の肺線維化を促進する2022
- Author(s)
  岡野智仁、Valeria F.DAlessandro、古橋一樹、大岩綾香、鶴賀龍樹、齊木晴子、藤原拓海、浅山健太郎、高橋佳紀、都丸敦史、中原博紀、藤本源、岡野優子、竹下敦郎、安間太郎、CND Gabazza、Esteban C. Gabazza、小林哲
- Organizer
  第６２回呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08203
[Presentation] ブレオマイシン肺線維症マウスモデルにおける肺内細菌叢由来の細胞死因子の経時的変化の検討2022
- Author(s)
  都丸敦史、齊木晴子、鶴賀龍樹、藤原拓海、岡野智仁、浅山健太郎、高橋佳紀、中原博紀、藤本源、CND Gabazza、Esteban C. Gabazza、小林哲
- Organizer
  第６２回呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08203
[Presentation] ブドウ球菌由来のアポトーシス促進ペプチドはブレオマイシン誘発肺線維症モデルにおいて慢性期の肺線維化を促進する2022
- Author(s)
  岡野智仁,VF DAlessandro、古橋一樹、大岩綾香、鶴賀龍樹、齊木晴子、藤原拓海、浅山健太郎、高橋佳紀、都丸敦史、中原博紀、藤本源、岡野優子、竹下敦郎、安間太郎、CND Gabazza、Esteban C. Gabazza、小林哲
- Organizer
  第６２回呼吸器学会
- Data Source
  KAKENHI-PROJECT-21K08203

1. Gabazza Esteban (00293770)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
2. Kobayashi Tetsu (20437114)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. 戸田雅昭 (10202201)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 竹下敦郎 (10830490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 安間太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 都丸敦史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. GABAZZA CORINA

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujimoto Hajime 藤本 源

Research Projects

Research Products

Co-Researchers

COVID-19における肺傷害促進因子Corisinの検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a new treatment for COVID-19-related acute lung injury targeting the microbiota-derived peptide corisin

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Microbiome in the Development of Lung Cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Adenine Nucleotide Translocases and Cellular Senescence in Idiopathic Pulmonary Fibrosis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Close-to-lesion transbronchial biopsy: a novel technique to improve suitability of specimens for genetic testing in patients with peripheral pulmonary lesions2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Amelioration of Pulmonary Fibrosis by Matrix Metalloproteinase-2 Overexpression.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epoprostenol and Treprostinil: Differential Effects on Regulatory T-Cell Generation in Patients with Pulmonary Arterial Hypertension2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic Value of CXCL12 in Non-Small Cell Lung Cancer Patients Undergoing Tumor Resection2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elevated plasma and bile levels of corisin, a microbiota-derived proapoptotic peptide, in patients with severe acute cholangitis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of a Microbiota-Derived Peptide Ameliorates Established Acute Lung Injury2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Response of Lung Microbiota to Changes of Pulmonary Innate Immunity under Healthy Conditions2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Microbial Burden-associated Cytokine Storm May Explain Nonresolving Acute Respiratory Distress Syndrome in Patients with COVID-192022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Microbiome-Derived Peptide Induces Apoptosis of Cells from Different Tissues2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Corisinは肺線維症のバイオマーカーとなりうる2023

Author(s)

Organizer

Data Source

[Presentation] 肺内細菌叢由来ペプチドの炎症促進作用2023

Author(s)

Organizer

Data Source

Fujimoto Hajime 藤本源