FUJITA Shujiro 藤田秀次郎

Researcher Number	90381516
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2018: 横浜市立大学, 医学研究科, 共同研究員 2014 – 2015: 横浜市立大学, 附属病院, 助教
Review Section/Research Field	Principal Investigator Embryonic/Neonatal medicine Except Principal Investigator Pediatrics
Keywords	Principal Investigator 早産児 / 動脈管 / アミノ酸 / グルタミン酸 / 動脈管開存症 Except Principal Investigator リモデリング / シグナル伝達 / 生理学 / 発生・分化 / 動脈管

Molecular mechanisms of remodeling of the ductus arteriosus
- Principal Investigator
  
  Yokoyama Utako
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Yokohama City University
Glutamate Promotes Contraction of the Rat Ductus ArteriosusPrincipal Investigator
- Principal Investigator
  
  FUJITA Shujiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Yokohama City University

All 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Epac1 deficiency inhibits basic fibroblast growth factor-mediated vascular smooth muscle cell migration2019
- Author(s)
  Yuko Kato, Utako Yokoyama, Takayuki Fujita, Masanari Umemura, Tetsuo Kubota, Yoshihiro Ishikawa
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 69 Issue: 2 Pages: 175-184
- DOI
  10.1007/s12576-018-0631-7
- NAID
  40021818894
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08976, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-18KT0073
[Journal Article] Usefulness of Exchanged Protein Directly Activated by cAMP (Epac)1-Inhibiting Therapy for Prevention of Atrial and Ventricular Arrhythmias in Mice2019
- Author(s)
  Prajapati R, Fujita T, Suita K, Nakamura T, Cai W, Hidaka Y, Umemura M, Yokoyama U, Knollmann BC, Okumura S, Ishikawa Y
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 2 Pages: 295-303
- DOI
  10.1253/circj.CJ-18-0743
- NAID
  130007557004
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2019-01-25
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06862, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-17K15560, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-15K18973, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-19K08563, KAKENHI-PROJECT-18K15013
[Journal Article] A selective antagonist of prostaglandin E receptor subtype 4 attenuates abdominal aortic aneurysm.2018
- Author(s)
  Mamun A, Yokoyama U, Saito J, Ito S, Hiromi T, Umemura M, Fujita T, Yasuda S, Minami T, Goda M, Uchida K, Suzuki S, Masuda M, Ishikawa Y.
- Journal Title
  
  Physiol Rep.
  
  Volume: 6 Issue: 18
- DOI
  10.14814/phy2.13878
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358
[Journal Article] Acute hyperthermia inhibits TGF-β1-induced cardiac fibroblast activation via uppression of Akt Signaling.2018
- Author(s)
  Narikawa M, Umemura M, Tanaka R, Fujita T, Yokoyama U, Ishigami T, Kimura K, Tamura K, Ishikawa Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 6277-6277
- DOI
  10.1038/s41598-018-24749-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-17K09730
[Journal Article] Hydrostatic pressure suppressed fibrotic change via Akt/GSK-3 signaling in human cardiac fibroblasts.2018
- Author(s)
  Tanaka R, Umemura M, Narikawa M, Fujita T, Yokoyama U, Ishigami T, Kimura K, Tamura K, Ishikawa Y.
- Journal Title
  
  Physiol Rep.
  
  Volume: 6 Issue: 9 Pages: e13687-e13687
- DOI
  10.14814/phy2.13687
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-17K09730
[Journal Article] Treatment of oral cancer using magnetized paclitaxel2018
- Author(s)
  Nakakaji Rina、Umemura Masanari、Mitsudo Kenji、Kim Jeong-Hwan、Hoshino Yujiro、Sato Itaru、Masuda Takatsugu、Yamamoto Masahiro、Kioi Mitomu、Koizumi Toshiyuki、Fujita Takayuki、Yokoyama Utako、Iida Masaki、Sato Motohiko、以下7名
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 21 Pages: 15591-15605
- DOI
  10.18632/oncotarget.24570
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08508, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-26463053, KAKENHI-PROJECT-18K05307, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16K11730, KAKENHI-PROJECT-15H05761
[Journal Article] Vidarabine, an anti-herpesvirus agent, prevents catecholamine-induced arrhythmias without adverse effect on heart function in mice2018
- Author(s)
  Suita Kenji、Fujita Takayuki、Cai Wenqian、Hidaka Yuko、Jin Huiling、Prajapati Rajesh、Umemura Masanari、Yokoyama Utako、Sato Motohiko、Knollmann Bj?rn C.、Okumura Satoshi、Ishikawa Yoshihiro
- Journal Title
  
  Pfl?gers Archiv - European Journal of Physiology
  
  Volume: 未定 Issue: 6 Pages: 923-935
- DOI
  10.1007/s00424-018-2121-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08508, KAKENHI-PROJECT-15K18973, KAKENHI-PROJECT-17K01828, KAKENHI-PROJECT-18K06862, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358
[Journal Article] Alternating magnetic field (AMF) enhances cytotoxicity of compound c.2018
- Author(s)
  Akimoto T, Umemura M, Nagasako A, Ohtake M, Fujita T, Yokoyama U, Eguchi H, Yamamoto T, Ishikawa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 109 Issue: 11 Pages: 3483-3493
- DOI
  10.1111/cas.13781
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-18K16592, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358
[Journal Article] Simultaneous hyperthermia-chemotherapy effect by arterial injection of Fe(Salen) for femur tumor2018
- Author(s)
  Umemura Masanari、Islam Md. Rafikul、Fukumura Hidenobu、Sato Itaru、Kawabata Yusuke、Matsuo Kousuke、Nakakaji Rina、Nagasako Akane、Ohtake Makoto、Takayuki Fujita、Yokoyama Utako、Nakayama Tomohiro、Eguchi Haruki、Ishikawa Yoshihiro
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 1 Pages: 356-365
- DOI
  10.1111/cas.13851
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-19K08563, KAKENHI-PROJECT-18K16592
[Journal Article] The iron chelating agent, deferoxamine detoxifies Fe(Salen)-induced cytotoxicity2017
- Author(s)
  Umemura Masanari、Kim Jeong-Hwan、Aoyama Haruki、Hoshino Yujiro、Fukumura Hidenobu、Nakakaji Rina、Sato Itaru、Ohtake Makoto、Akimoto Taisuke、Narikawa Masatoshi、Tanaka Ryo、Fujita Takayuki、Yokoyama Utako、Taguri Masataka、Okumura Satoshi、Sato Motohiko、Eguchi Haruki、Ishikawa Yoshihiro
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 134 Issue: 4 Pages: 203-210
- DOI
  10.1016/j.jphs.2017.07.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300
[Journal Article] Cardiac overexpression of Epac1 in transgenic mice rescues lipopolysaccharide-induced cardiac dysfunction and inhibits Jak-STAT pathway.2017
- Author(s)
  Huiling Jin, Takayuki Fujita, Meihua Jin, Reiko Kurotani, Iyuki Namekata, Shogo Hamaguchi, Yuko Hidaka, Wenqian Cai, Kenji Suita, Yoshiki Ohnuki, Yasumasa Mototani, Kouichi Shiozawa, Rajesh Prajapati, Chen Liang, Masanari Umemura, Utako Yokoyama, Motohiko Sato, Hikaru Tanaka, Satoshi Okumura, Yoshihiro Ishikawa.
- Journal Title
  
  J Mol Cell Cardiol.
  
  Volume: 108 Pages: 170-180
- DOI
  10.1016/j.yjmcc.2017.05.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08607, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15K18973, KAKENHI-PROJECT-17K15460, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-15K08247, KAKENHI-PROJECT-15K09208, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300
[Journal Article] Arterial graft with elastic layer structure grown from cells.2017
- Author(s)
  Yokoyama U, Tonooka Y, Koretake R, Akimoto T, Gonda Y, Saito J, Umemura M, Fujita T, Sakuma S, Arai F, Kaneko M, Ishikawa Y.
- Journal Title
  
  Sci Rep
  
  Volume: 1 Issue: 1 Pages: 140-140
- DOI
  10.1038/s41598-017-00237-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-25293236, KAKENHI-PROJECT-16K15205, KAKENHI-PROJECT-26670506, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300
[Journal Article] Glutamate Promotes Contraction of the Rat Ductus Arteriosus2016
- Author(s)
  S. Fujita, U. Yokoyama, R. Ishiwata, R. Aoki, K. Nagao, D. Masukawa, M. Umemura, T. Fujita, S. Iwasaki, S. Nishimaki, K. Seki, S. Ito, Y. Goshima, T. Asou, M. Masuda, and Y. Ishikawa
- Journal Title
  
  Circ J
  
  Volume: 80 Issue: 11 Pages: 2388-2396
- DOI
  10.1253/circj.CJ-16-0649
- NAID
  130005433144
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-14J01039, KAKENHI-PROJECT-26461639, KAKENHI-PROJECT-16K15205
[Journal Article] Epac activation inhibits IL-6-induced cardiac myocyte dysfunction.2016
- Author(s)
  Jin H，Fujita T，Jin M，Kurotani R，Hidaka Y，Cai W，Suita K，Prajapati R，Liang C，Ohnuki Y，Mototani Y，Umemura M，Yokoyama U，Sato M，Okumura S，Ishikawa Y.
- Journal Title
  
  J Physiol Sci.
  
  Volume: 印刷中 Issue: 1 Pages: 77-87
- DOI
  10.1007/s12576-016-0509-5
- NAID
  40021443658
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16K15205, KAKENHI-PROJECT-15K18975, KAKENHI-PROJECT-16K08508, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-15K09208, KAKENHI-PROJECT-18K08138, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-18K19689, KAKENHI-PROJECT-15H05761
[Journal Article] Glutamate promotes contraction of the rat ductus arteriosus.2016
- Author(s)
  Fujita S, Yokoyama U, Ishiwata R, Aoki R, Nagao K, Masukawa D, Umemura M, Fujita T, Iwasaki S, Nishimaki S, Seki K, Ito S, Goshima Y, Asou T, Masuda M, Ishikawa Y.
- Journal Title
  
  Circ J
  
  Volume: 80 Pages: 2388-2396
- NAID
  130005433144
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05358
[Journal Article] Transient receptor potential cation 3 channel regulates melanoma proliferation and migration．2016
- Author(s)
  Oda K，Umemura M，Nakakaji R，Tanaka R，Sato I，Nagasako A，Oyamada C，Baljinnyam E，Katsumata M，Xie L，Narikawa M，Yamaguchi Y，Akimoto T，Ohtake M，Fujita T，Yokoyama U，Iwatsubo K，Aihara M and Ishikawa Y
- Journal Title
  
  J Physiol Sci.
  
  Volume: 該当なし Issue: 4 Pages: 497-505
- DOI
  10.1007/s12576-016-0480-1
- NAID
  40021238419
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16K15205, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-15H05761
[Presentation] Epac1 deficiency inhibits bFGF-induced neointimal formation via diminished phosphorylation of GSK3beta.2018
- Author(s)
  Kato, Y., Yokoyama, U., Fujita, T., Kubota, T. Ishikawa, Y.
- Organizer
  The 95th Annual Meeting of the Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-16H05358

1. Yokoyama Utako (70404994)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. NAMEKATA Iyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 石川義弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
4. 藤田孝之

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
5. 梅村将就

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
6. 齋藤純一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 奥村敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 加藤優子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 佐藤元彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

FUJITA Shujiro 藤田 秀次郎

Research Projects

Research Products

Co-Researchers

Molecular mechanisms of remodeling of the ductus arteriosus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Glutamate Promotes Contraction of the Rat Ductus ArteriosusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Epac1 deficiency inhibits basic fibroblast growth factor-mediated vascular smooth muscle cell migration2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Usefulness of Exchanged Protein Directly Activated by cAMP (Epac)1-Inhibiting Therapy for Prevention of Atrial and Ventricular Arrhythmias in Mice2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] A selective antagonist of prostaglandin E receptor subtype 4 attenuates abdominal aortic aneurysm.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acute hyperthermia inhibits TGF-β1-induced cardiac fibroblast activation via uppression of Akt Signaling.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hydrostatic pressure suppressed fibrotic change via Akt/GSK-3 signaling in human cardiac fibroblasts.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Treatment of oral cancer using magnetized paclitaxel2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vidarabine, an anti-herpesvirus agent, prevents catecholamine-induced arrhythmias without adverse effect on heart function in mice2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Alternating magnetic field (AMF) enhances cytotoxicity of compound c.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simultaneous hyperthermia-chemotherapy effect by arterial injection of Fe(Salen) for femur tumor2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The iron chelating agent, deferoxamine detoxifies Fe(Salen)-induced cytotoxicity2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cardiac overexpression of Epac1 in transgenic mice rescues lipopolysaccharide-induced cardiac dysfunction and inhibits Jak-STAT pathway.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Arterial graft with elastic layer structure grown from cells.2017

Author(s)

Journal Title

DOI

FUJITA Shujiro 藤田秀次郎