Koide Keiko 小出馨子

… Alternative Names

KOIDE Keiko 小出馨子

小出馨子コイデケイコ

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Researcher Number	90384437
Other IDs
Affiliation (Current)	2025: 昭和大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2015 – 2024: 昭和大学, 医学部, 講師 2012 – 2016: 昭和大学, 医学部, 助教 2005 – 2006: 昭和大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 57080:Social dentistry-related / Periodontology
Keywords	Principal Investigator 妊娠高血圧腎症 / DNAメチル化 / 妊娠高血圧症候群 / 産科学 / 癒着胎盤 / なし / 胎盤機能評価 / hPL / hCG / 絨毛mRNA … More / cell-free RNA / 定量PCR / 遺伝子発現 / 胎盤 / 血漿中Cell-free RNA … More Except Principal Investigator 妊娠高血圧症候群 / 子宮内フローラ / 早産 / 胎児発育不全 / DNAメチル化 / フローラ / プレコンセプションケア / FGR / 不育 / 再発 / 子宮内細菌叢 / 慢性子宮内感染 / 常位胎盤早期剥離 / 母体血中cell-free RNA / 胎盤機能 / 低体重児出産 / 妊娠糖尿病 / 歯周病 / 胎盤 / 胎児発育 / 絨毛細胞分化 / 絨毛細胞 / エピジェネティクス / 初期絨毛 / 喫煙 / 妊娠初期絨毛 / 妊娠絨毛 Less

プレコンセプションケアでの口腔管理の必要性を不育早産FGR患者細菌叢から検証する
- Principal Investigator
  
  小出容子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Showa University
Development a method to predict preeclampsia using maternal plasma DNA/RNAPrincipal Investigator
- Principal Investigator
  
  Koide Keiko
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Showa University
Study on the mechanism of placental abruption from the viewpoint of uterine microbiota
- Principal Investigator
  
  Sekizawa Akihiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Showa University
Endometrial microbiota in women with recurrent pregnancy loss without common risk factors and the effect of administering prebiotics
- Principal Investigator
  
  Kondo Tetsurou
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Showa University
The study for development of prediction method of placental adhesion, using cell-free DNA in maternal bloodPrincipal Investigator
- Principal Investigator
  
  Koide Keiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Showa University
Analysis of cell-free mRNA in first trimester plasma from pregnant women who would develop fetal growth restriction or hepertensive disorders of pregnancy
- Principal Investigator
  
  Takenaka Shin
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Showa University
The alterations of villous DNA methylation in first trimester associated with the pathogenesis of preeclampsia
- Principal Investigator
  
  Sekizawa Akihiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Showa University
Alteration of villous DNA methylation associated with fetal growth resriction
- Principal Investigator
  
  Takenaka Shin
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Showa University
The Effects of Periodontal Disease as a Risk for Preterm Birth and Low Birth-Weight Infants in Women with Gestational Diabetes Mellitus.
- Principal Investigator
  
  Koide Yoko
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Showa University
Placental DNA methylation pattern in preeclampsiaPrincipal Investigator
- Principal Investigator
  
  KOIDE Keiko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Showa University
母体血漿中cell-free mRNAを用いた胎盤機能評価法の開発Principal Investigator
- Principal Investigator
  
  小出馨子
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Showa University

All 2015 2014 2013 2012 2007 2005 Other

All Journal Article Presentation

[Journal Article] Prediction of Fetal Growth Restriction by Analyzing the Messenger RNAs of Angiogenic Factor in the Plasma of Pregnant Women2015
- Author(s)
  Takenaka S, Ventura W, Sterrantino AF, Kawashima A, Koide K, Hori K, Farina A, Sekizawa A
- Journal Title
  
  Reproductive Sciences
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462501
[Journal Article] Maternal Smoking History Enhances the Expression of Placental Growth Factor in Invasive Trophoblasts at Early Gestation Despite Cessation of Smoking2015
- Author(s)
  Kawashima A, Koide K, Hasegawa J, Arakaki T, Takenaka S, Maruyama D, Matsuoka R, Sekizawa A.
- Journal Title
  
  PLoS One
  
  Volume: １０ Issue: 7 Pages: e0134181-e0134181
- DOI
  10.1371/journal.pone.0134181
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462501
[Journal Article] Vitamin C Induces the Reduction of Oxidative Stress and Paradoxically Stimulates the Apoptotic Gene Expression in Extravillous Trophoblasts Derived From First-Trimester Tissue2015
- Author(s)
  Kawashima A, Sekizawa A, Koide K, Hasegawa J, Satoh K, Arakaki T, Takenaka S, Matsuoka R
- Journal Title
  
  Reproductive Sciences
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462501
[Journal Article] Prediction of Fetal Growth Restriction by Analyzing the Messenger RNAs of Angiogenic Factor in the Plasma of Pregnant Women2015
- Author(s)
  Takenaka S, Ventura W, Sterrantino AF, Kawashima A, Koide K, Hori K, Farina A, Sekizawa A.
- Journal Title
  
  Reprod Sci.
  
  Volume: 22 Issue: 6 Pages: 743-749
- DOI
  10.1177/1933719114557895
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462501
[Journal Article] Vitamin C Induces the Reduction of Oxidative Stress and Paradoxically Stimulates the Apoptotic Gene Expression in Extravillous Trophoblasts Derived From First-Trimester Tissue2015
- Author(s)
  Kawashima A, Sekizawa A, Koide K, Hasegawa J, Satoh K, Arakaki T, Takenaka S, Matsuoka R.
- Journal Title
  
  Reprod Sci.
  
  Volume: 22 Issue: 7 Pages: 783-790
- DOI
  10.1177/1933719114561561
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462501
[Journal Article] Effects of maternal smoking on the placental expression of genes related to angiogenesis and apoptosis during the first trimester2014
- Author(s)
  Kawashima A, Koide K, Ventura W, Hori K, Takenaka S, Maruyama D, Matsuoka R, Ichizuka K, Sekizawa A
- Journal Title
  
  PloS One
  
  Volume: 9 Issue: 8 Pages: e106140-e106140
- DOI
  10.1371/journal.pone.0106140
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462501
[Journal Article] Cell-free mRNA concentrations of PAI-1 and tPA are increased in the plasma of pregnant women with pre-eclampsia2007
- Author(s)
  Yuditiya Purwosunu, Akihiko Sekizawa, Keiko Koide, Antonio Farina, Noroyono Wibowo, Gulardi Hanifa Wiknjosastro, Shiho Okazaki, Hiroshi Chiba, Takashi Okai
- Journal Title
  
  Clinical Chemistry (In press)
- Data Source
  KAKENHI-PROJECT-17791137
[Journal Article] Fragmentation of cell-free fetal DNA in plasma and urine of pregnant women.2005
- Author(s)
  Koide K, Sekizawa A, Iwasaki M, Matsuoka R, Honma S, Farina A, Saito H, Okai T
- Journal Title
  
  Prenatal Diagnosis 25(7)
  
  Pages: 604-607
- Data Source
  KAKENHI-PROJECT-17791137
[Journal Article] 【メタボリックシンドロームと周産期管理】プログラミングに果たす胎盤の役割
- Author(s)
  小出馨子, 関沢明彦, 竹中慎, 鈴木稚子, 岡井崇
- Journal Title
  
  周産期医学
  
  Volume: 42巻,7号 Pages: 855-859
- Data Source
  KAKENHI-PROJECT-24791723
[Presentation] 絨毛におけるDNA メチル化異常とpreeclampsia の発症に関する検討2013
- Author(s)
  小出馨子, 堀恭子, 竹中慎, 丸山大介, 松岡隆, 市塚清健, 関沢明彦
- Organizer
  第34回妊娠高血圧学会学術集会
- Place of Presentation
  富山
- Year and Date
  2013-10-04
- Data Source
  KAKENHI-PROJECT-24791723
[Presentation] ヒト初期絨毛遺伝子の変化に着目した妊娠高血圧症候群発症の予知と予防2013
- Author(s)
  小出馨子
- Organizer
  第65会日本産科婦人科学会学術講演会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24791723
[Presentation] Placental DNA methylation pattern in preeclampsia2013
- Author(s)
  Keiko Koide, Kyoko Hori, Satoshi Miyagami, Shin Takenaka, Akihiro Kawashima, Hiroshi Chiba, Akihiko Sekizawa
- Organizer
  2013 International Federation of Placenta Associations Meeting
- Place of Presentation
  カナダ
- Data Source
  KAKENHI-PROJECT-24791723
[Presentation] Placental DNA methylation pattern in preeclampsia2013
- Author(s)
  Keiko Koide, Kyoko Hori, Satoshi Miyagami, Shin Takenaka, Akihiro Kawashima, Hiroshi Chiba, Akihiko Sekizawa
- Organizer
  International Society For the Study of Hypertesion in Pregnancy World Congress
- Place of Presentation
  カナダ(ウィスラー)
- Year and Date
  2013-09-12
- Data Source
  KAKENHI-PROJECT-24791723
[Presentation] シンポジウム2(周産期)妊娠高血圧症候群の基礎と臨床 -予防・治療の新戦略に向けて-ヒト初期絨毛遺伝子の変化に着目した妊娠高血圧症候群発症の予知と予防2013
- Author(s)
  小出馨子
- Organizer
  第65回日本産科婦人科学会学術講演会
- Place of Presentation
  北海道
- Year and Date
  2013-05-11
- Data Source
  KAKENHI-PROJECT-24791723
[Presentation] 妊娠高血圧症候群と胎盤のDNA methylationに関する研究2012
- Author(s)
  小出馨子、関沢明彦、宮上哲、四元淳子、仲村将光、大石親護、岡井崇
- Organizer
  第64回日本産科婦人科学会学術講演会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24791723
[Presentation] 崇妊娠高血圧症候群と胎盤のDNA methylationに関する研究2012
- Author(s)
  小出馨子, 関沢明彦, 宮上哲, 四元淳子, 仲村将光, 大石親護,岡井
- Organizer
  第64回日本産科婦人科学会学術講演会
- Place of Presentation
  神戸
- Year and Date
  2012-04-13
- Data Source
  KAKENHI-PROJECT-24791723
[Presentation] 絨毛におけるDNAメチル化異常とpreeclampsiaの発症に関する検討
- Author(s)
  小出　馨子、堀　恭子、竹中　慎、丸山　大介、松岡　隆、市塚　清健、関沢　明彦
- Organizer
  第34回妊娠高血圧学会学術集会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-24791723
[Presentation] Placental DNA methylation pattern in preeclampsia
- Author(s)
  Keiko Koide、Kyoko Hori、Satoshi Miyagami、Shin Takenaka、Akihiro Kawashima、Hiroshi Chiba、Akihiko Sekizawa
- Organizer
  International Society For the Study of Hypertesion in Pregnancy World Congress
- Place of Presentation
  ウィスラー（カナダ）
- Data Source
  KAKENHI-PROJECT-24791723
[Presentation] シンポジウム2（周産期）妊娠高血圧症候群の基礎と臨床　－予防・治療の新戦略に向けて- ヒト初期絨毛遺伝子の変化に着目した妊娠高血圧症候群発症の予知と予防
- Author(s)
  小出　馨子
- Organizer
  第65回日本産科婦人科学会学術講演会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-24791723

1. SEKIZAWA Akihiko (10245839)

# of Collaborated Projects: 7 results

# of Collaborated Products: 14 results
2. TAKENAKA Shin (60515211)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
3. Koide Yoko (40407466)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 四元淳子 (30553648)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 大槻克文 (90276527)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 川嶋章弘 (10783376)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YAMAMOTO Matsuo (50332896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OKAMATSU Yoshimasa (50286845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Kondo Tetsurou (30365754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 岡田裕美子 (70622059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 河本貴之 (80817594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OSAMURA Anna

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOHASHI Kyoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TOMOYASU Masako

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OBA Tomohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Koide Keiko 小出 馨子

KOIDE Keiko 小出 馨子

小出 馨子 コイデ ケイコ

Research Projects

Research Products

Co-Researchers

プレコンセプションケアでの口腔管理の必要性を不育早産FGR患者細菌叢から検証する

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development a method to predict preeclampsia using maternal plasma DNA/RNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on the mechanism of placental abruption from the viewpoint of uterine microbiota

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Endometrial microbiota in women with recurrent pregnancy loss without common risk factors and the effect of administering prebiotics

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study for development of prediction method of placental adhesion, using cell-free DNA in maternal bloodPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of cell-free mRNA in first trimester plasma from pregnant women who would develop fetal growth restriction or hepertensive disorders of pregnancy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The alterations of villous DNA methylation in first trimester associated with the pathogenesis of preeclampsia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Alteration of villous DNA methylation associated with fetal growth resriction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Effects of Periodontal Disease as a Risk for Preterm Birth and Low Birth-Weight Infants in Women with Gestational Diabetes Mellitus.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Placental DNA methylation pattern in preeclampsiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

母体血漿中cell-free mRNAを用いた胎盤機能評価法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Prediction of Fetal Growth Restriction by Analyzing the Messenger RNAs of Angiogenic Factor in the Plasma of Pregnant Women2015

Author(s)

Journal Title

Data Source

[Journal Article] Maternal Smoking History Enhances the Expression of Placental Growth Factor in Invasive Trophoblasts at Early Gestation Despite Cessation of Smoking2015

Author(s)

Journal Title

DOI

Koide Keiko 小出馨子

KOIDE Keiko 小出馨子

小出馨子コイデケイコ