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Koide Keiko  小出 馨子

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KOIDE Keiko  小出 馨子

小出 馨子  コイデ ケイコ

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Researcher Number 90384437
Other IDs
Affiliation (Current) 2025: 昭和大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2015 – 2024: 昭和大学, 医学部, 講師
2012 – 2016: 昭和大学, 医学部, 助教
2005 – 2006: 昭和大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related
Except Principal Investigator
Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related / Basic Section 57080:Social dentistry-related / Periodontology
Keywords
Principal Investigator
妊娠高血圧腎症 / DNAメチル化 / 妊娠高血圧症候群 / 産科学 / 癒着胎盤 / なし / 胎盤機能評価 / hPL / hCG / 絨毛mRNA … More / cell-free RNA / 定量PCR / 遺伝子発現 / 胎盤 / 血漿中Cell-free RNA … More
Except Principal Investigator
妊娠高血圧症候群 / 子宮内フローラ / 早産 / 胎児発育不全 / DNAメチル化 / フローラ / プレコンセプションケア / FGR / 不育 / 再発 / 子宮内細菌叢 / 慢性子宮内感染 / 常位胎盤早期剥離 / 母体血中cell-free RNA / 胎盤機能 / 低体重児出産 / 妊娠糖尿病 / 歯周病 / 胎盤 / 胎児発育 / 絨毛細胞分化 / 絨毛細胞 / エピジェネティクス / 初期絨毛 / 喫煙 / 妊娠初期絨毛 / 妊娠絨毛 Less
  • Research Projects

    (11 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (15 People)
  •  プレコンセプションケアでの口腔管理の必要性を不育早産FGR患者細菌叢から検証する

    • Principal Investigator
      小出 容子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57080:Social dentistry-related
    • Research Institution
      Showa University
  •  Development a method to predict preeclampsia using maternal plasma DNA/RNAPrincipal Investigator

    • Principal Investigator
      Koide Keiko
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Showa University
  •  Study on the mechanism of placental abruption from the viewpoint of uterine microbiota

    • Principal Investigator
      Sekizawa Akihiko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Showa University
  •  Endometrial microbiota in women with recurrent pregnancy loss without common risk factors and the effect of administering prebiotics

    • Principal Investigator
      Kondo Tetsurou
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Showa University
  •  The study for development of prediction method of placental adhesion, using cell-free DNA in maternal bloodPrincipal Investigator

    • Principal Investigator
      Koide Keiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Showa University
  •  Analysis of cell-free mRNA in first trimester plasma from pregnant women who would develop fetal growth restriction or hepertensive disorders of pregnancy

    • Principal Investigator
      Takenaka Shin
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Showa University
  •  The alterations of villous DNA methylation in first trimester associated with the pathogenesis of preeclampsia

    • Principal Investigator
      Sekizawa Akihiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Showa University
  •  Alteration of villous DNA methylation associated with fetal growth resriction

    • Principal Investigator
      Takenaka Shin
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Showa University
  •  The Effects of Periodontal Disease as a Risk for Preterm Birth and Low Birth-Weight Infants in Women with Gestational Diabetes Mellitus.

    • Principal Investigator
      Koide Yoko
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontology
    • Research Institution
      Showa University
  •  Placental DNA methylation pattern in preeclampsiaPrincipal Investigator

    • Principal Investigator
      KOIDE Keiko
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Showa University
  •  母体血漿中cell-free mRNAを用いた胎盤機能評価法の開発Principal Investigator

    • Principal Investigator
      小出 馨子
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Showa University

All 2015 2014 2013 2012 2007 2005 Other

All Journal Article Presentation

  • [Journal Article] Prediction of Fetal Growth Restriction by Analyzing the Messenger RNAs of Angiogenic Factor in the Plasma of Pregnant Women2015

    • Author(s)
      Takenaka S, Ventura W, Sterrantino AF, Kawashima A, Koide K, Hori K, Farina A, Sekizawa A
    • Journal Title

      Reproductive Sciences

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26462501
  • [Journal Article] Maternal Smoking History Enhances the Expression of Placental Growth Factor in Invasive Trophoblasts at Early Gestation Despite Cessation of Smoking2015

    • Author(s)
      Kawashima A, Koide K, Hasegawa J, Arakaki T, Takenaka S, Maruyama D, Matsuoka R, Sekizawa A.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 7 Pages: e0134181-e0134181

    • DOI

      10.1371/journal.pone.0134181

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462501
  • [Journal Article] Vitamin C Induces the Reduction of Oxidative Stress and Paradoxically Stimulates the Apoptotic Gene Expression in Extravillous Trophoblasts Derived From First-Trimester Tissue2015

    • Author(s)
      Kawashima A, Sekizawa A, Koide K, Hasegawa J, Satoh K, Arakaki T, Takenaka S, Matsuoka R
    • Journal Title

      Reproductive Sciences

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26462501
  • [Journal Article] Prediction of Fetal Growth Restriction by Analyzing the Messenger RNAs of Angiogenic Factor in the Plasma of Pregnant Women2015

    • Author(s)
      Takenaka S, Ventura W, Sterrantino AF, Kawashima A, Koide K, Hori K, Farina A, Sekizawa A.
    • Journal Title

      Reprod Sci.

      Volume: 22 Issue: 6 Pages: 743-749

    • DOI

      10.1177/1933719114557895

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462501
  • [Journal Article] Vitamin C Induces the Reduction of Oxidative Stress and Paradoxically Stimulates the Apoptotic Gene Expression in Extravillous Trophoblasts Derived From First-Trimester Tissue2015

    • Author(s)
      Kawashima A, Sekizawa A, Koide K, Hasegawa J, Satoh K, Arakaki T, Takenaka S, Matsuoka R.
    • Journal Title

      Reprod Sci.

      Volume: 22 Issue: 7 Pages: 783-790

    • DOI

      10.1177/1933719114561561

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462501
  • [Journal Article] Effects of maternal smoking on the placental expression of genes related to angiogenesis and apoptosis during the first trimester2014

    • Author(s)
      Kawashima A, Koide K, Ventura W, Hori K, Takenaka S, Maruyama D, Matsuoka R, Ichizuka K, Sekizawa A
    • Journal Title

      PloS One

      Volume: 9 Issue: 8 Pages: e106140-e106140

    • DOI

      10.1371/journal.pone.0106140

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462501
  • [Journal Article] Cell-free mRNA concentrations of PAI-1 and tPA are increased in the plasma of pregnant women with pre-eclampsia2007

    • Author(s)
      Yuditiya Purwosunu, Akihiko Sekizawa, Keiko Koide, Antonio Farina, Noroyono Wibowo, Gulardi Hanifa Wiknjosastro, Shiho Okazaki, Hiroshi Chiba, Takashi Okai
    • Journal Title

      Clinical Chemistry (In press)

    • Data Source
      KAKENHI-PROJECT-17791137
  • [Journal Article] Fragmentation of cell-free fetal DNA in plasma and urine of pregnant women.2005

    • Author(s)
      Koide K, Sekizawa A, Iwasaki M, Matsuoka R, Honma S, Farina A, Saito H, Okai T
    • Journal Title

      Prenatal Diagnosis 25(7)

      Pages: 604-607

    • Data Source
      KAKENHI-PROJECT-17791137
  • [Journal Article] 【メタボリックシンドロームと周産期管理】プログラミングに果たす胎盤の役割

    • Author(s)
      小出馨子, 関沢明彦, 竹中慎, 鈴木稚子, 岡井崇
    • Journal Title

      周産期医学

      Volume: 42巻,7号 Pages: 855-859

    • Data Source
      KAKENHI-PROJECT-24791723
  • [Presentation] 絨毛におけるDNA メチル化異常とpreeclampsia の発症に関する検討2013

    • Author(s)
      小出馨子, 堀恭子, 竹中慎, 丸山大介, 松岡隆, 市塚清健, 関沢明彦
    • Organizer
      第34回妊娠高血圧学会学術集会
    • Place of Presentation
      富山
    • Year and Date
      2013-10-04
    • Data Source
      KAKENHI-PROJECT-24791723
  • [Presentation] ヒト初期絨毛遺伝子の変化に着目した妊娠高血圧症候群発症の予知と予防2013

    • Author(s)
      小出馨子
    • Organizer
      第65会日本産科婦人科学会学術講演会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24791723
  • [Presentation] Placental DNA methylation pattern in preeclampsia2013

    • Author(s)
      Keiko Koide, Kyoko Hori, Satoshi Miyagami, Shin Takenaka, Akihiro Kawashima, Hiroshi Chiba, Akihiko Sekizawa
    • Organizer
      2013 International Federation of Placenta Associations Meeting
    • Place of Presentation
      カナダ
    • Data Source
      KAKENHI-PROJECT-24791723
  • [Presentation] Placental DNA methylation pattern in preeclampsia2013

    • Author(s)
      Keiko Koide, Kyoko Hori, Satoshi Miyagami, Shin Takenaka, Akihiro Kawashima, Hiroshi Chiba, Akihiko Sekizawa
    • Organizer
      International Society For the Study of Hypertesion in Pregnancy World Congress
    • Place of Presentation
      カナダ(ウィスラー)
    • Year and Date
      2013-09-12
    • Data Source
      KAKENHI-PROJECT-24791723
  • [Presentation] シンポジウム2(周産期)妊娠高血圧症候群の基礎と臨床 -予防・治療の新戦略に向けて-ヒト初期絨毛遺伝子の変化に着目した妊娠高血圧症候群発症の予知と予防2013

    • Author(s)
      小出馨子
    • Organizer
      第65回日本産科婦人科学会学術講演会
    • Place of Presentation
      北海道
    • Year and Date
      2013-05-11
    • Data Source
      KAKENHI-PROJECT-24791723
  • [Presentation] 妊娠高血圧症候群と胎盤のDNA methylationに関する研究2012

    • Author(s)
      小出馨子、関沢明彦、宮上哲、四元淳子、仲村将光、大石親護、岡井崇
    • Organizer
      第64回日本産科婦人科学会学術講演会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24791723
  • [Presentation] 崇妊娠高血圧症候群と胎盤のDNA methylationに関する研究2012

    • Author(s)
      小出馨子, 関沢明彦, 宮上哲, 四元淳子, 仲村将光, 大石親護,岡井
    • Organizer
      第64回日本産科婦人科学会学術講演会
    • Place of Presentation
      神戸
    • Year and Date
      2012-04-13
    • Data Source
      KAKENHI-PROJECT-24791723
  • [Presentation] 絨毛におけるDNAメチル化異常とpreeclampsiaの発症に関する検討

    • Author(s)
      小出 馨子、堀 恭子、竹中 慎、丸山 大介、松岡 隆、市塚 清健、関沢 明彦
    • Organizer
      第34回妊娠高血圧学会学術集会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-24791723
  • [Presentation] Placental DNA methylation pattern in preeclampsia

    • Author(s)
      Keiko Koide、Kyoko Hori、Satoshi Miyagami、Shin Takenaka、Akihiro Kawashima、Hiroshi Chiba、Akihiko Sekizawa
    • Organizer
      International Society For the Study of Hypertesion in Pregnancy World Congress
    • Place of Presentation
      ウィスラー(カナダ)
    • Data Source
      KAKENHI-PROJECT-24791723
  • [Presentation] シンポジウム2(周産期)妊娠高血圧症候群の基礎と臨床 -予防・治療の新戦略に向けて- ヒト初期絨毛遺伝子の変化に着目した妊娠高血圧症候群発症の予知と予防

    • Author(s)
      小出 馨子
    • Organizer
      第65回日本産科婦人科学会学術講演会
    • Place of Presentation
      北海道
    • Data Source
      KAKENHI-PROJECT-24791723
  • 1.  SEKIZAWA Akihiko (10245839)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 14 results
  • 2.  TAKENAKA Shin (60515211)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 12 results
  • 3.  Koide Yoko (40407466)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  四元 淳子 (30553648)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  大槻 克文 (90276527)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  川嶋 章弘 (10783376)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  YAMAMOTO Matsuo (50332896)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  OKAMATSU Yoshimasa (50286845)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  Kondo Tetsurou (30365754)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  岡田 裕美子 (70622059)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  河本 貴之 (80817594)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  OSAMURA Anna
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KOHASHI Kyoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TOMOYASU Masako
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  OBA Tomohiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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