HISHIKAWA Hiroyuki 西川裕之

… Alternative Names

西川裕之ニシカワヒロユキ

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Researcher Number	90387077
Affiliation (Current)	2025: 聖マリアンナ医科大学, 医学研究科, 研究技術員
Affiliation (based on the past Project Information) *help	2016 – 2023: 聖マリアンナ医科大学, 医学研究科, 研究技術員 2013 – 2015: 聖マリアンナ医科大学, 医学(系)研究科(研究院), 研究技術員 2012: 聖マリアンナ医科大学, 医学(系)研究科(研究院), その他 2010 – 2011: St.Marianna University School of Medicine, 医学(系)研究科(研究院), 研究技術員 2009: St.Marianna University School of Medicine, 医学研究科, 研究技術員 2007 – 2008: St.Marianna University School of Medicine, Inst. Adv. Med. Sci., Research Associate 2006: 聖マリアンナ医科大学, 医学部, 研究補助員
Review Section/Research Field	Principal Investigator General surgery / Basic Section 50010:Tumor biology-related Except Principal Investigator Plant pathology / Obstetrics and gynecology
Keywords	Principal Investigator 脱ユビキチン化 / DNA修復 / 癌抑制遺伝子 / 遺伝子 / 乳癌 / ユビキチン化 / DSB応答タンパク質 / ガン抑制遺伝子 / 癌 / 癌遺伝子 … More Except Principal Investigator … More ゲノム結合蛋白質 / 翻訳開始因子 / ポティウイルス / シロイヌナズナ / 子宮頸部扁平上皮癌 / 扁平上皮癌 / 子宮頸癌 / レクチンマイクロアレイ / genome-linked protein / translation initiation factor / Potyvirus / Arabidopsis thaliana / ボティウイルス / ゲノム結合タンパク質 / 増殖 / 感染 Less

Functional analysis of the tumor suppressor gene BAP1 and DSB response.Principal Investigator
- Principal Investigator
  
  Nishikawa Hiroyuki
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  St. Marianna University School of Medicine
Functional analysis of tumor suppressor gene BAP1, NPM1 complexPrincipal Investigator
- Principal Investigator
  
  Nishikawa Hiroyuki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  St. Marianna University School of Medicine
Glycan profiling using formalin-fixed, paraffin-embedded tissues: Hippeastrum hybrid lectin is a sensitive biomarker for squamous cell carcinoma of the cervix
- Principal Investigator
  
  Tozawa-Ono Akiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  St. Marianna University School of Medicine
Functional analysis of BRCA1/BAP1 complexPrincipal Investigator
- Principal Investigator
  
  NISHIKAWA Hiroyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  St. Marianna University School of Medicine
Interaction between Potyvirus viral protein linked to the genome and host cell protein
- Principal Investigator
  
  MIYOSHI Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plant pathology
- Research Institution
  St.Marianna University School of Medicine
A functional analysis of stabilizing factor BAP1 of cancer-restraining gene BRCA1Principal Investigator
- Principal Investigator
  
  NISHIKAWA Hiroyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  St.Marianna University School of Medicine
癌抑制遺伝子BAP1の作用機構の解明Principal Investigator
- Principal Investigator
  
  西川裕之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  St.Marianna University School of Medicine
Studies on roles of potyviral protein on plant viral disease
- Principal Investigator
  
  MIYOSHI Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plant pathology
- Research Institution
  St.Marianna University School of Medicine

All 2016 2015 2012 2011 2010 2009 2006

All Journal Article Presentation

[Journal Article] Functional Link between BRCA1 and BAP1 through Histone H2A, Heterochromatin and DNA Damage Response.2016
- Author(s)
  Fukuda T, Tsuruga T, Kuroda T, Nishikawa H, Ohta T.
- Journal Title
  
  Curr Cancer Drug Targets.
  
  Volume: 16(2) Issue: 2 Pages: 101-9
- DOI
  10.2174/1568009615666151030102427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461962, KAKENHI-PLANNED-24112005, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26290042
[Journal Article] Ubiquitin acetylation inhibits polyubiquitin chain elongation.2015
- Author(s)
  Ohtake F, Saeki Y, Sakamoto K, Ohtake K, Nishikawa H, Tsuchiya H, Ohta T, Tanaka K, Kanno J.
- Journal Title
  
  EMBO Reports
  
  Volume: 16(2) Pages: 192-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461962
[Journal Article] Liganded ERα Stimulates the E3 Ubiquitin Ligase Activity of UBE3C to Facilitate Cell Proliferation.2015
- Author(s)
  Okada M, Ohtake F, Nishikawa H, Wu W, Saeki Y, Takana K, Ohta T.
- Journal Title
  
  Mol Endocrinol.
  
  Volume: 29(11) Pages: 1646-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461962
[Journal Article] Interaction of BARD1 and HP1 Is Required for BRCA1 Retention at Sites of DNA Damage.2015
- Author(s)
  Wu W, Nishikawa H, Fukuda T, Vittal V, Asano M, Miyoshi Y, Klevit RE, Ohta T.
- Journal Title
  
  Cancer Research
  
  Volume: 75(7) Pages: 1311-1321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461962
[Journal Article] A DNA-Damage Selective Role for BRCA1 E3 Ligase in Claspin Ubiquitylation, CHK1 Activation, and DNA Repair2012
- Author(s)
  Sato K, Sundaramoorthy E, Rajendra E, Hattori H, Jeyasekharan AD, Ayoub N, Schiess R, Aebersold R, Nishikawa H, Sedukhina AS, Wada H, Ohta T, Venkitaraman AR.
- Journal Title
  
  Curr Biol
  
  Volume: 22 Pages: 1659-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791504
[Journal Article] DNA相同組換え修復と乳癌2012
- Author(s)
  太田智彦、西川裕之
- Journal Title
  
  メディカルサイエンスダイジェスト
  
  Volume: Vol38(1) Pages: 637-640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791504
[Journal Article] HERC2 Interacts with Claspin and regulates DNA origin firing and replication fork progression2011
- Author(s)
  Izawa N, Wu W, Sato K, Nishikawa H, Kato A, Boku N, Itoh F, Ohta T.
- Journal Title
  
  Cancer Res
  
  Volume: 71 Pages: 5621-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791504
[Journal Article] HERC2 is an E3 ligase that targets BRCA1 for degradation.2010
- Author(s)
  Wu W, Sato K, Koike A, Nishikawa H, Koizumi H, Venkitaraman AR, Ohta T.
- Journal Title
  
  Cancer Res. 70(15)
  
  Pages: 6384-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790939
[Journal Article] Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates.2010
- Author(s)
  Koike A, Nishikawa H, Wu W, Okada Y, Venkitaraman AR, Ohta T.
- Journal Title
  
  Cancer Res. 70(17)
  
  Pages: 6746-6756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790939
[Journal Article] BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity.2009
- Author(s)
  Nishikawa H, Wu W, Koike A, Kojima R, Gomi H, Fukuda M, Ohta T.
- Journal Title
  
  Cancer Res. 69(1)
  
  Pages: 111-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790939
[Journal Article] Overexpression of heat shock protein 27 in squamous cell carcinoma of the uterine cervix : a proteomic analysis using archival formalin-fixed, paraffin-embedded tissues.2009
- Author(s)
  Ono A, Kumai T, Koizumi H, Nishikawa H, Kobayashi S, Tadokoro M.
- Journal Title
  
  Hum Pathol. 40(1)
  
  Pages: 41-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790939
[Journal Article] BRCA1-Associated Proteinl Interferes with BRCAIBARD1 RING Heterodimer Activity2009
- Author(s)
  Hiroyuki Nishikawa
- Journal Title
  
  Cancer Research 69(1)
  
  Pages: 111-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790939
[Journal Article] Novel recognition sequence of coxsackievirus 2A proteinase2006
- Author(s)
  Shinji Muto, Hiroshi Miyoshi, Hiroyuki Nishikawa, Hideki Nakashima
- Journal Title
  
  Biochemical and Biophysical Research Communications Vol.348
  
  Pages: 1436-1442
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580045
[Presentation] Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates2011
- Author(s)
  Ayaka Koike, Hiroyuki Nishikawa, Wenwen Wu, Yukinori Okada, Ashok R Venkitaraman, Tomohiko Ohta
- Organizer
  EMBO Workshop・The Interface between the Ubiquitin Family and the DNA Damage Response
- Place of Presentation
  Rovinj, Croatia
- Data Source
  KAKENHI-PROJECT-23791504

1. MIYOSHI Hiroshi (80322519)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. NATSUAKI Tomohide (10134264)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TOMOO Koji (70257898)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Tozawa-Ono Akiko (90569865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KOIZUMI Hirotaka (10215155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KUMAI Toshio (40139671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HISHIKAWA Hiroyuki 西川 裕之

西川 裕之 ニシカワ ヒロユキ

Research Projects

Research Products

Co-Researchers

Functional analysis of the tumor suppressor gene BAP1 and DSB response.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of tumor suppressor gene BAP1, NPM1 complexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Glycan profiling using formalin-fixed, paraffin-embedded tissues: Hippeastrum hybrid lectin is a sensitive biomarker for squamous cell carcinoma of the cervix

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of BRCA1/BAP1 complexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Interaction between Potyvirus viral protein linked to the genome and host cell protein

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A functional analysis of stabilizing factor BAP1 of cancer-restraining gene BRCA1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

癌抑制遺伝子BAP1の作用機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on roles of potyviral protein on plant viral disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Functional Link between BRCA1 and BAP1 through Histone H2A, Heterochromatin and DNA Damage Response.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ubiquitin acetylation inhibits polyubiquitin chain elongation.2015

Author(s)

Journal Title

Data Source

[Journal Article] Liganded ERα Stimulates the E3 Ubiquitin Ligase Activity of UBE3C to Facilitate Cell Proliferation.2015

Author(s)

Journal Title

Data Source

[Journal Article] Interaction of BARD1 and HP1 Is Required for BRCA1 Retention at Sites of DNA Damage.2015

Author(s)

Journal Title

Data Source

[Journal Article] A DNA-Damage Selective Role for BRCA1 E3 Ligase in Claspin Ubiquitylation, CHK1 Activation, and DNA Repair2012

Author(s)

Journal Title

Data Source

[Journal Article] DNA相同組換え修復と乳癌2012

Author(s)

Journal Title

Data Source

[Journal Article] HERC2 Interacts with Claspin and regulates DNA origin firing and replication fork progression2011

Author(s)

HISHIKAWA Hiroyuki 西川裕之

西川裕之ニシカワヒロユキ