HIRASE Hajime 平瀬肇

Researcher Number	90392084
Other IDs	https://orcid.org/0000-0003-3806-6905
Affiliation (based on the past Project Information) *help	2018 – 2019: 国立研究開発法人理化学研究所, 脳神経科学研究センター, チームリーダー 2015 – 2017: 国立研究開発法人理化学研究所, 脳科学総合研究センター, チームリーダー 2014: 独立行政法人理化学研究所, 脳科学総合研究センタ-, チームリーダー 2014: 理化学研究所, 脳科学総合研究センター, 神経グリア回路研究チームリーダー 2011 – 2012: 独立行政法人理化学研究所, 神経グリア回路研究チーム, チームリーダー … More 2008 – 2010: 独立行政法人理化学研究所, 平瀬研究ユニット, ユニットリーダー 2007: The Institute of Physical and Chemical Research, 平瀬研究ユニット, ユニットリーダー 2005 – 2006: 独立行政法人理化学研究所, 平瀬研究ユニット, ユニットリーダー Less
Review Section/Research Field	Principal Investigator Biological Sciences / Biological Sciences / Brain biometrics / Basic / Social brain science / Neuroscience in general Except Principal Investigator Neuroscience in general / Neuroscience in general / Basic / Social brain science / Neurosurgery / Fusional basic brain science / Biological Sciences
Keywords	Principal Investigator アストロサイト / グリア / 神経細胞 / 大脳皮質 / イメージング / 海馬 / 神経科学 / ニューロピル / シナプス伝達 / カルシウム … More / 可塑性 / 細胞外記録 / 神経修飾物質 / アストログリア / 大脳新皮質 / 脳 / ニューロン・グリア / GCaMP / 脳・神経 / ニューロングリア相互作用 / グリア細胞 / 脳波 / 学習 / 記憶 / マウス / イン・ビボ / アセチルコリン / メゾスコピック / シナプス / 脳左右差 / 分子・細胞神経科学 / カイニン酸 / in vivo記録 / 細胞内記録 / 二光子イメージング / 神経活動 / 発火活動 / 多点同時記録 / シータ波 / 麻酔 / 場所細胞 / 錐体細胞 … More Except Principal Investigator カルシウム / アストロサイト / in vivo / マイネルト基底核 / 大脳皮質 / グリア / AAV9 / 可塑性 / オプトジェネティクス / シナプス可塑性 / マウス / グリア細胞 / カルシウム計測 / イン・ビボ / 2光子顕微鏡 / アセチルコリン / イメージング / 長期増強 / カルシウムシグナル / 免疫組織化学 / ミクログリア / tDCS / 二光子顕微鏡 / 脳血流調節 / 脳血管障害学 / ２光子顕微鏡 / 脳血流障害 / 微小循環 / 神経刺激 / 脳循環予備能 / 一酸化炭素 / 脳虚血 / 脳微小循環 / シナプス / 二光子 / バレル / 慢性計測 / ウイルス / 二光子イメージング / 光刺激 / ２光子励起顕微鏡 / ヒゲ / 脳血流 / 2光子レーザー顕微鏡 / 小脳縦縞構造 / チャネルロドプシン / 2光子励起レーザー顕微鏡 / アデノウイルス / 2光子励起顕微鏡 / マウス視覚野 / 縦縞構造 / マウス小脳皮質 / チャンネルロドウプシン2 / 皮質可塑性 / ラット / 光子顕微鏡 / 覚醒 / G-CaMP / ケイジドグルタミン酸 / ニューロン / 海馬 Less

神経修飾物質による皮質アストロサイトの中長期的な活動観測と機能的意義の解明Principal Investigator
- Principal Investigator
  
  平瀬肇
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Institute of Physical and Chemical Research
Cortical circuit plasticity supported by gliaPrincipal Investigator
- Principal Investigator
  
  Hirase Hajime
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Basic / Social brain science
- Research Institution
  Institute of Physical and Chemical Research
Role of carbon monoxide and astrocyte on cerebral microcirculation
- Principal Investigator
  
  Ishikawa Mami
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Institute of Physical and Chemical Research
Extraction of neurite signals from neuropil calcium signalingPrincipal Investigator
- Principal Investigator
  
  Hirsae Hajime
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Brain biometrics
- Research Institution
  Institute of Physical and Chemical Research
chronic measurement of glial dynamics for response to plasticity induction in vivo
- Principal Investigator
  
  Mishima Tsuneko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Basic / Social brain science
- Research Institution
  Institute of Physical and Chemical Research
生体内で起こる皮質回路シナプス可塑性におけるアストロサイトの役割Principal Investigator
- Principal Investigator
  
  平瀬肇
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Institute of Physical and Chemical Research
Astricyte dynamics in synaptic plascitity in vivo
- Principal Investigator
  
  TSUNEKO Mishima
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Fusional basic brain science
- Research Institution
  The Institute of Physical and Chemical Research
皮質回路シナプス可塑性に伴う生体脳神経グリア回路の変化Principal Investigator
- Principal Investigator
  
  平瀬肇
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Investigation of astrocytic involvement in the cortical plasiticity in vivo
- Principal Investigator
  
  TAKATA Norio
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Keio University
  The Institute of Physical and Chemical Research
Cerebellar microstructures and their electrophysiological and functional properties
- Principal Investigator
  
  OZEKI Hirofumi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  The Institute of Physical and Chemical Research
哺乳類脳機能の左右差の意義解明のために、左右半球を連絡する原因分子を同定するPrincipal Investigator
- Principal Investigator
  
  平瀬肇
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neuroscience in general
- Research Institution
  The Institute of Physical and Chemical Research
Investigation of cortical microcircuit upon meynert nucleus-induced cortical plasticity
- Principal Investigator
  
  TAKATA Norio
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  The Institute of Physical and Chemical Research
Investigation on the effects of Basal Forebrain Nuclei on the cortical micro circuit in relation with sleep and awake regulation
- Principal Investigator
  
  TAKATA Norio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  The Institute of Physical and Chemical Research
皮質アストログリア細胞の生体内(イン・ビボ)での動態計測Principal Investigator
- Principal Investigator
  
  平瀬肇
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
皮質内嗅野-海馬間のインターラクションPrincipal Investigator
- Principal Investigator
  
  平瀬肇
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
ケージドグルタミン酸を用いた多点同時刺激による海馬ニューロンの長期増強の解析
- Principal Investigator
  
  中井淳一
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research

[Book] Optical imaging of cortical circuit dynamics2013
- Author(s)
  Norio Takata, Yoshiaki Shinohara, Masamichi Ohkura, Tsuneko Mishima, Junichi Nakai, Hajime Hirase
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23700399
[Journal Article] Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance2020
- Author(s)
  Oe Yuki、Wang Xiaowen、Patriarchi Tommaso、Konno Ayumu、Ozawa Katsuya、Yahagi Kazuko、Hirai Hirokazu、Tian Lin、McHugh Thomas J.、Hirase Hajime
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 471-471
- DOI
  10.1038/s41467-020-14378-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06899, KAKENHI-PUBLICLY-18H05150, KAKENHI-PUBLICLY-19H05233, KAKENHI-PROJECT-16H01888, KAKENHI-PROJECT-18H02521
[Journal Article] Transcranial Direct Current Stimulation (tDCS) Induces Adrenergic Receptor-Dependent Microglial Morphological Changes in Mice2019
- Author(s)
  Mishima Tsuneko、Nagai Terumi、Yahagi Kazuko、Akther Sonam、Oe Yuki、Monai Hiromu、Kohsaka Shinichi、Hirase Hajime
- Journal Title
  
  eneuro
  
  Volume: 6 Issue: 5 Pages: 0214-0214
- DOI
  10.1523/eneuro.0204-19.2019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05150, KAKENHI-PROJECT-16H01888, KAKENHI-PROJECT-18K14859
[Journal Article] Regional Distribution of Glycogen in the Mouse Brain Visualized by Immunohistochemistry2019
- Author(s)
  Oe Yuki、Akther Sonam、Hirase Hajime
- Journal Title
  
  Adv Neurobiology
  
  Volume: 23 Pages: 147-168
- DOI
  10.1007/978-3-030-27480-1_5
- ISBN
  9783030274795, 9783030274801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H01888
[Journal Article] Pioglitazone reversed the fructose-programmed astrocytic glycolysis and oxidative phosphorylation of female rat offspring2019
- Author(s)
  Wu Chih-Wei、Hung Chun-Ying、Hirase Hajime、Tain You-Lin、Lee Wei-Chia、Chan Julie Y. H.、Fu Mu-Hui、Chen Lee-Wei、Liu Wen-Chung、Liang Chih-Kuang、Ho Ying-Hao、Kung Yu Chih、Leu Steve、Wu Kay L. H.
- Journal Title
  
  American Journal of Physiology-Endocrinology and Metabolism
  
  Volume: 316 Issue: 4 Pages: E622-E634
- DOI
  10.1152/ajpendo.00408.2018
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H05150, KAKENHI-PROJECT-16H01888
[Journal Article] Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke2019
- Author(s)
  Monai Hiromu、Wang Xiaowen、Yahagi Kazuko、Lou Nanhong、Mestre Humberto、Xu Qiwu、Abe Yoichiro、Yasui Masato、Iwai Youichi、Nedergaard Maiken、Hirase Hajime
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 116 Issue: 22 Pages: 11010-11019
- DOI
  10.1073/pnas.1817347116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05150, KAKENHI-PROJECT-16H01888, KAKENHI-PROJECT-18H02606, KAKENHI-PROJECT-18K14859
[Journal Article] Glycogen distribution in mouse hippocampus2019
- Author(s)
  Hirase Hajime、Akther Sonam、Wang Xiaowen、Oe Yuki
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 印刷中 Issue: 8 Pages: 923-932
- DOI
  10.1002/jnr.24386
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H05150, KAKENHI-PROJECT-16H01888
[Journal Article] Aquaporin-4-dependent glymphatic solute transport in the rodent brain2018
- Author(s)
  H. Mestre*, LM. Hablitz*, ALB. Xavier*, W. Feng*, W. Zou*, T. Pu*, H. Monai*, G. Murlidharan*, RM. Castellanos Rivera*, MJ. Simon*, MM. Pike*, V. Pla*, T. Du*, BT. Kress*, X. Wang, BA. Plog, AS. Thrane, I. Lundgaard, Y. Abe, M. Yasui, JH. Thomas, M. Xiao, H. Hirase, A. Asokan, JJ. Iliff, M. Nedergaard
- Journal Title
  
  eLife
  
  Volume: 7
- DOI
  10.7554/elife.40070
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14859, KAKENHI-PUBLICLY-18H05150, KAKENHI-PROJECT-18H02606, KAKENHI-PROJECT-16H01888, KAKENHI-PROJECT-17K19637, KAKENHI-PROJECT-16H05134
[Journal Article] Astrocytes as a target of transcranial direct current stimulation (tDCS) to treat depression2018
- Author(s)
  Monai Hiromu、Hirase Hajime
- Journal Title
  
  Neuroscience Research
  
  Volume: 126 Pages: 15-21
- DOI
  10.1016/j.neures.2017.08.012
- NAID
  120006501608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H01888, KAKENHI-PROJECT-16K13116
[Journal Article] A spherical aberration-free microscopy system for live brain imaging2018
- Author(s)
  Ue Yoshihiro、Monai Hiromu、Higuchi Kaori、Nishiwaki Daisuke、Tajima Tetsuya、Okazaki Kenya、Hama Hiroshi、Hirase Hajime、Miyawaki Atsushi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 500 Issue: 2 Pages: 236-241
- DOI
  10.1016/j.bbrc.2018.04.049
- NAID
  40021394427
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H01888, KAKENHI-PROJECT-16K13116, KAKENHI-PROJECT-18K14859, KAKENHI-PLANNED-15H05948
[Journal Article] グリア活性化による脳可塑性の向上─経頭蓋直流電気刺激（tDCS）の作用機序として2018
- Author(s)
  平瀬　肇、三嶋　恒子、毛内　　拡
- Journal Title
  
  Dementia Japan
  
  Volume: 32 Pages: 17-23
- Data Source
  KAKENHI-PROJECT-16K13116
[Journal Article] Enhancement of neural plasticity by glial activation : a possible mechanism of transcranial direct current stimulation2017
- Author(s)
  Hajime Hirase, Tuneko Mishima, Hiromu Monai
- Journal Title
  
  Dementia Japan
  
  Volume: 32 Pages: 17-23
- NAID
  40021483012
- Data Source
  KAKENHI-PROJECT-15K01841
[Journal Article] Rearing-environment-dependent hippocampal local field potential differences in wild-type and inositol trisphosphate receptor type 2 knockout mice2017
- Author(s)
  Tanaka Mika、Wang Xiaowen、Mikoshiba Katsuhiko、Hirase Hajime、Shinohara Yoshiaki
- Journal Title
  
  The Journal of Physiology
  
  Volume: 595 Issue: 20 Pages: 6557-6568
- DOI
  10.1113/jp274573
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-16H01888, KAKENHI-PROJECT-17H02221
[Journal Article] Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain2016
- Author(s)
  H Monai, M Ohkura, M Tanaka, Y Oe, A Konno, H Hirai, K Mikoshiba, S Itohara, J Nakai, Y Iwai & H Hirase
- Journal Title
  
  Nature communications
  
  Volume: 7 Issue: 1 Pages: 11100-11100
- DOI
  10.1038/ncomms11100
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14326, KAKENHI-PROJECT-15K18330, KAKENHI-PUBLICLY-15H01275, KAKENHI-PUBLICLY-26115504, KAKENHI-PUBLICLY-26117520, KAKENHI-PROJECT-15H05723, KAKENHI-PROJECT-26640002, KAKENHI-PROJECT-26282217, KAKENHI-PROJECT-25221002
[Journal Article] Glycogen distribution in the microwave-fixed mouse brain reveals heterogeneous astrocytic patterns2016
- Author(s)
  Oe Y, Baba O, Ashida H, Nakamura KC, Hirase H
- Journal Title
  
  Glia
  
  Volume: 64 Issue: 9 Pages: 1532-1545
- DOI
  10.1002/glia.23020
- NAID
  120007001408
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H01888, KAKENHI-PROJECT-16K13116
[Journal Article] Astrocytic calcium activation in a mouse model of tDCS - extended discussion2016
- Author(s)
  Monai H, Hirase H
- Journal Title
  
  Neurogenesis
  
  Volume: - Issue: 1 Pages: e1240055-e1240055
- DOI
  10.1080/23262133.2016.1240055
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H01888, KAKENHI-PROJECT-16K13116
[Journal Article] Involvement of astrocytes in neurovascular communication2016
- Author(s)
  Nuriya M, Hirase, H.
- Journal Title
  
  Progress in Brain Research
  
  Volume: in press Pages: 41-62
- DOI
  10.1016/bs.pbr.2016.02.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26117520, KAKENHI-PROJECT-26650052
[Journal Article] Adaptive changes of extracellular amino acid concentrations in mouse dorsal striatum by 4-AP-induced cortical seizures2015
- Author(s)
  Terumi Nagai, Norio Takata, Yoshiaki Shinohara, Hajime Hirase
- Journal Title
  
  Neuroscience
  
  Volume: 295 Pages: 229-236
- DOI
  10.1016/j.neuroscience.2015.03.043
- NAID
  120006386964
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25115726, KAKENHI-PROJECT-25430011, KAKENHI-PROJECT-26282222, KAKENHI-PROJECT-15KT0111, KAKENHI-PUBLICLY-26117520
[Journal Article] Imaging of astrocytic activity in living rodents.2014
- Author(s)
  Takata N, Shinohara Y, Ohkura M, Mishima T, Nakai J, *Hirase H
- Journal Title
  
  Neuromethods
  
  Volume: 85 Pages: 191-207
- DOI
  10.1007/978-1-62703-785-3_12
- ISBN
  9781627037846, 9781627037853
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24111509, KAKENHI-PROJECT-24500475, KAKENHI-PUBLICLY-25115726, KAKENHI-PUBLICLY-25116504, KAKENHI-PROJECT-25430011
[Journal Article] Volume transmission signaling via astrocytes.2014
- Author(s)
  Hirase H, Iwai Y, Takata N, Shinohara Y, Mishima T
- Journal Title
  
  Philos Trans R Soc Lond B Biol Sci.
  
  Volume: in press
- NAID
  120006386963
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500475
[Journal Article] Volume transmission signalling via astrocytes.2014
- Author(s)
  Hirase H, Iwai Y, Takata N, AShinohara Y Mishima T
- Journal Title
  
  Philos Trans R Soc Lond B Biol Sci.
  
  Volume: 369 Issue: 1654 Pages: 20130604-20130604
- DOI
  10.1098/rstb.2013.0604
- NAID
  120006386963
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500475, KAKENHI-PUBLICLY-26117520, KAKENHI-PROJECT-26282222
[Journal Article] Transformation of cortical and hippocampal neural circuit by environmental enrichment.2014
- Author(s)
  Hirase, H, Shinohara Y.
- Journal Title
  
  Neuroscience
  
  Volume: 280 Pages: 282-298
- DOI
  10.1016/j.neuroscience.2014.09.031
- NAID
  120006386962
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26117520, KAKENHI-PROJECT-26282222
[Journal Article] Cerebral blood flow modulation by basal forebrain or whisker stimulation can occur independent of large cytosolic Ca2+ signaling in astrocytes.2013
- Author(s)
  Takata N, Nagai T, Ozawa K, Oe Y, Mikoshiba K, Hirase H
- Journal Title
  
  PLoS ONE
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700399
[Journal Article] Cerebral blood flow modulation by basal forebrain or whisker stimulation can occur independent of large cytosolic Ca2+ signaling in astrocytes2013
- Author(s)
  Norio TAKATA, Terumi Nagai, Katsuya Ozawa, Yuki Oe, Katsuhiko Mikoshiba, Hajime Hirase
- Journal Title
  
  PLoS ONE
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700399
[Journal Article] 脳波オシレーション：病態の解析およびバイオマーカーとしての可能性2012
- Author(s)
  平瀬　肇
- Journal Title
  
  実験医学
  
  Volume: 30 Pages: 2092-2096
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23115522
[Journal Article] Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo2011
- Author(s)
  Takata N, Mishima T, Hisatsune C, NagaiT, Ebisui E, Mikoshiba K, Hirase H
- Journal Title
  
  J Neurosci
  
  Volume: 31(49) Pages: 18155-18165
- NAID
  120006386959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23700399
[Journal Article] Remodeling of monoplanar purkinje cell dendrites during cerebellar circuit formation.2011
- Author(s)
  Megumi Kaneko, Kazuhiko Yamaguchi, Mototsugu Eiraku, Motohiko Sato, Norio Takata, Yoshimoto Kiyohara, Masayoshi Mishina, Hajime Hirase, Tsutomu Hashikawa, Mineko Kengaku.
- Journal Title
  
  PLoS ONE (in press)
- NAID
  120003163707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700374
[Journal Article] A simple head-mountable LED device for chronic stimulation of opto-genetic molecules in freely moving mice2011
- Author(s)
  Iwai Y, Honda S, Ozeki H, Hashimoto M, Hirase H
- Journal Title
  
  Neuroscience Research
  
  Volume: 70 Pages: 124-127
- NAID
  120006386955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700357
[Journal Article] Remodeling of monoplanar Purkinje cell dendrites during cerebellar circuit formation2011
- Author(s)
  Kaneko, M., Yamaguchi, K., Eiraku, M., Sato, M., Takata, N., Kiyohara, Y., Mishina, M., Hirase, H., Hashikawa, T. and Kengaku, M
- Journal Title
  
  PLoS ONE
  
  Volume: 6 Issue: 5 Pages: e20108-e20108
- DOI
  10.1371/journal.pone.0020108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249012, KAKENHI-PLANNED-22123008, KAKENHI-PROJECT-23500472, KAKENHI-PROJECT-23700399
[Journal Article] Astrocyte calcium signaling transforms cholinergic modulation to cortical plastcity in vivo2011
- Author(s)
  Takata N
- Journal Title
  
  J Neurosci
  
  Volume: 31(49) Issue: 49 Pages: 18155-65
- DOI
  10.1523/jneurosci.5289-11.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220007, KAKENHI-PUBLICLY-23115522, KAKENHI-PROJECT-23700399
[Journal Article] Cortical layer 1 and layer 2/3 astrocytes exhibit distinct calcium dynamics in vivo2008
- Author(s)
  Takata Norio, Hirase Hajime
- Journal Title
  
  PLoS ONE 3(6)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19700306
[Journal Article] イン・ビボにおけるアストロサイトの動態計測2007
- Author(s)
  平瀬肇, 高田則雄
- Journal Title
  
  BRAIN and NERVE 59(7)
  
  Pages: 773-781
- Data Source
  KAKENHI-PROJECT-19700306
[Journal Article] イン・ビボにおけるアストロサイトの動態計測2007
- Author(s)
  平瀬肇
- Journal Title
  
  Brain Nerve 59
  
  Pages: 773-781
- Data Source
  KAKENHI-PROJECT-18053026
[Journal Article] イン・ビボにおけるアストロサイトの動態計測2007
- Author(s)
  平瀬肇、高田則雄
- Journal Title
  
  Brain and Nerve 59
  
  Pages: 773-781
- Data Source
  KAKENHI-PROJECT-19700306
[Presentation] マウス大脳皮質アストロサイトCa2+およびcAMPの動態2019
- Author(s)
  大江祐樹（平瀬に代わり）
- Organizer
  第9回都医学研シンポジウム：グリア細胞機能の新展開から脳機能のさらなる理解
- Invited
- Data Source
  KAKENHI-PROJECT-16H01888
[Presentation] Macroscopic imaging of cortical spreading depression and recovery2019
- Author(s)
  平瀬肇
- Organizer
  International Conference on Neurological Disorders and Therapeutics (ICNDT) 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01888
[Presentation] Heterogeneity of astrocytes in glycogen distribution and calcium dynamics2019
- Author(s)
  平瀬肇
- Organizer
  第42回日本神経科学年会Neuro2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01888
[Presentation] Astrocytic GPCR Activation in Behaving and Stroke Mice2019
- Author(s)
  平瀬　肇
- Organizer
  Gordon Conference on Glial Biology: Functional Interactions Among Glia and Neurons
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05150
[Presentation] Heterogeneity of astrocytes in glycogen distribution and calcium dynamics2019
- Author(s)
  平瀬　肇
- Organizer
  第42回日本神経科学年会Neuro2019
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05150
[Presentation] Astrocytic GPCR Activation in Behaving and Stroke Mice2019
- Author(s)
  平瀬　肇
- Organizer
  Gordon Conference: "Glial Biology: Functional Interactions Among Glia and Neurons"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01888
[Presentation] Transcranial direct current stimulation triggers cortical metaplasticity via glial calcium elevation2018
- Author(s)
  Hirase H
- Organizer
  The first international symposium for frontend brain science of the University of Yamanashi
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01888
[Presentation] 経頭蓋直流電気刺激 (tDCS)によるマイクログリア細胞体の変化2018
- Author(s)
  三嶋恒子, 永井てるみ, 矢作和子, 毛内拡, 大江祐樹, 平瀬肇
- Organizer
  日本神経科学大会（神戸国際会議場）
- Data Source
  KAKENHI-PROJECT-15K01841
[Presentation] Brain glycogen distribution by glycogen immunohistochemistry in the mouse2018
- Author(s)
  Hirase H
- Organizer
  13th International Conference on Brain Energy Metabolism
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01888
[Presentation] Adrenergic receptor antagonism provides neuroprotection and facilitates recovery from cortical spreading depression/depolarization2018
- Author(s)
  平瀬　肇
- Organizer
  第２３回グリア研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H01888
[Presentation] Adrenergic receptor antagonism provides neuroprotection and facilitates rfecovery from cortical spreading depression/depolarization2018
- Author(s)
  平瀬　肇
- Organizer
  第23回グリア研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H05150
[Presentation] Imaging of neural activity during transcranial DC stimulation2017
- Author(s)
  Hirase H
- Organizer
  Two-photon Imaging Course, Chongqing
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13116
[Presentation] Transcranial direct current stimulation triggers cortical metaplasticity via glial calcium elevation2017
- Author(s)
  Hirase H
- Organizer
  20th International Symposium on Calcium Binding Proteins and Calcium Function in Health and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01888
[Presentation] Transcranial direct current stimulation alters microglial morphology in mice2017
- Author(s)
  Tsuneko Mishima, Yuki Oe, Hiromu Monai, Hajime Hirase
- Organizer
  Neuromodulation（New York）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01841
[Presentation] Transcranial direct current stimulation triggers cortical metaplasticity via glial calcium elevation2017
- Author(s)
  Hirase H
- Organizer
  International Symposium on Calcium Binding Proteins and Calcium Function in Health and Disease (CaBP20)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13116
[Presentation] 経頭蓋直流電気刺激 (tDCS)によるマイクログリア形態変化の解析2017
- Author(s)
  三嶋恒子, 永井てるみ, 矢作和子, 毛内拡, 大江祐樹, 平瀬肇
- Organizer
  日本神経科学大会(幕張メッセ)
- Data Source
  KAKENHI-PROJECT-15K01841
[Presentation] Transcranial Direct Current Stimulation Alters Microglial Morphology in Mice2017
- Author(s)
  Tsuneko Mishima, Yuki Oe, Hiromu Monai, Hajime Hirase
- Organizer
  neuromodulation
- Place of Presentation
  City college of New York、NY
- Year and Date
  2017-01-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01841
[Presentation] Role of astrocytic calcium elevation in transcranial direct current stimulation in mice2017
- Author(s)
  Hajime Hirase
- Organizer
  International Astrocyte School
- Place of Presentation
  ベルティノーロ大学,イタリア
- Year and Date
  2017-03-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01888
[Presentation] tDCS M etaplasticity and Astrocytic C alcium2017
- Author(s)
  Hajime Hirase
- Organizer
  NYC Neuromodulation
- Place of Presentation
  City College of New York, 米国
- Year and Date
  2017-01-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01888
[Presentation] アストロサイトGq GPCRの光遺伝学的活性化による神経活動の制御2017
- Author(s)
  Iwai Y, Ozawa K, Yahagi K, Sato S, Hirase H
- Organizer
  第40回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01888
[Presentation] Modulation of hippocampal local field potential patterns by rearing condition in inositol trisphosphate receptor type 2 knockout mice.2017
- Author(s)
  Wang X, Tanaka M, Shinohara Y, Mikoshiba K, Hirase H
- Organizer
  第40回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H01888
[Presentation] Cortical plasticity induced via volume transmitter-activated glia2016
- Author(s)
  Hirase H
- Organizer
  1st IBRO/APRC Chandigarh Neuroscience Symposium
- Place of Presentation
  Chandigarh, インド
- Year and Date
  2016-02-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26117520
[Presentation] Cerebral blood flow modulation can occur independently of large cytosolic Ca2+ signaling in astrocytes2015
- Author(s)
  Hirase H
- Organizer
  27th International Symposium on Cerebral Blood Flow, Metabolism and Function & 12th International Conference on Quantification of Brain Function with PET (BRAIN 2015)
- Place of Presentation
  Vancouver, カナダ
- Year and Date
  2015-06-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26117520
[Presentation] Cortical plasticity induced via volume transmitter-activated glia2015
- Author(s)
  Hirase H
- Organizer
  6th FAONS Congress and Chinese Neuroscience Society Conference
- Place of Presentation
  Wuzhen, 中国
- Year and Date
  2015-09-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26117520
[Presentation] 前脳基底部刺激および感覚刺激はアストロサイトCa2+シグナルとは独立に脳血流変化を起こす.2013
- Author(s)
  高田則雄、永井てるみ、小澤克也、御子柴克彦、平瀬肇
- Organizer
  第36回日本神経科学会
- Place of Presentation
  京都
- Year and Date
  2013-06-21
- Data Source
  KAKENHI-PROJECT-23700399
[Presentation] Cholinergic modulation of in vivo barrel cortical plasticity via astrocytes2012
- Author(s)
  平瀬　肇
- Organizer
  First International Symposium on In Vivo Microscopy
- Place of Presentation
  Helsinki, フィンランド
- Year and Date
  2012-05-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-23115522
[Presentation] Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo2012
- Author(s)
  平瀬　肇
- Organizer
  SFB 894 Calcium Signaling
- Place of Presentation
  Homburg, ドイツ
- Year and Date
  2012-09-07
- Invited
- Data Source
  KAKENHI-PUBLICLY-23115522
[Presentation] マウスのバレル皮質における神経可塑性の特性解析2011
- Author(s)
  三嶋恒子、高田則雄、江口恵、山口瞬、平瀬肇
- Organizer
  第33回日本神経科学会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23700399
[Presentation] アストロサイトのカルシウム活動を介してコリン性調節は大脳皮質可塑性を誘導する.2011
- Author(s)
  高田則雄、三嶋恒子、久恒智博、永井てるみ、戎井悦子、御子柴克彦、平瀬肇
- Organizer
  第33回日本神経科学会
- Place of Presentation
  横浜
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-23700399
[Presentation] アストロサイトが局所電場電位(LFP)に与える影響2011
- Author(s)
  平瀬肇
- Organizer
  第54回日本神経化学会
- Place of Presentation
  加賀
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PUBLICLY-23115522
[Presentation] アストロサイトのカルシウム活動を介してコリン性調節は大脳皮質可塑性を誘導する2011
- Author(s)
  高田則雄、三嶋恒子、久恒智博、永井てるみ、戎井悦子、御子柴克彦、平瀬肇
- Organizer
  第33回日本神経科学会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23700399
[Presentation] Astrocytic modulation of local field potential in vivo2011
- Author(s)
  平瀬肇
- Organizer
  第14回韓国脳神経科学大会
- Place of Presentation
  Seoul(ソウル),韓国
- Year and Date
  2011-09-20
- Data Source
  KAKENHI-PUBLICLY-23115522
[Presentation] The first evidence of astrocytic contribution to a sensory induced synaptic plasticity in the somatosensory cortex2010
- Author(s)
  Norio TAKATA, Tsuneko MISHIMA, Chihiro HISATSUNE, Etsuko EBISUI, Katsuhiko MIKOSHIBA, Hajime HIRASE.
- Organizer
  in vivo
- Place of Presentation
  シェラトン都ホテル東京
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-21700374
[Presentation] The first evidence of astrocytic contribution to a sensory induced synaptic plasticity in the somatosensory cortex2010
- Author(s)
  Norio TAKATA, Tsuneko MISHIMA, Chihiro HISATSUNE, Etsuko EBISUI Katsuhiko MIKOSHIBA, Hajime HIRASE.
- Organizer
  in vivo,内藤コンファレンス
- Place of Presentation
  湘南国際村センター
- Year and Date
  2010-10-06
- Data Source
  KAKENHI-PROJECT-21700374
[Presentation] Astrocytic contribution of a sensory induced synaptic plasticity in the somatosensory cortex2010
- Author(s)
  Norio TAKATA, Tsuneko MISHIMA, Chihiro HISATSUNE, Etsuko EBISUI, Katsuhiko MIKOSHIBA, Hajime HIRASE.
- Place of Presentation
  San Diego, USA.
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21700374
[Presentation] A strocytic Modulation of local field potential and synaptic plasticity2010
- Author(s)
  Hirase, Hajime
- Organizer
  第29回内藤コンファレンス「グリアワールドから見た脳」
- Place of Presentation
  神奈川県三浦郡
- Year and Date
  2010-10-06
- Data Source
  KAKENHI-PROJECT-21650081
[Presentation] 前脳基底部コリン作動性神経核は大脳皮質アストロサイトを活性化する2009
- Author(s)
  高田則雄、平瀬肇
- Organizer
  日本神経科学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-21700374
[Presentation] 前脳基底部コリン作動性神経核は大脳皮質アストロサイトを活性化する2009
- Author(s)
  高田則雄、平瀬肇
- Organizer
  第32回日本神経科学会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-21700374
[Presentation] 海馬・皮質アストロサイトからのin vivo細胞内記録法2008
- Author(s)
  平瀬肇
- Organizer
  海馬と高次脳機能学会(第16回)
- Place of Presentation
  奈良
- Year and Date
  2008-11-24
- Data Source
  KAKENHI-PROJECT-18053026
[Presentation] in vivoにおけるアストロサイトの自発的カルシウム活動は大脳皮質の第1層と第2/3層とで異なる2007
- Author(s)
  高田則雄, 平瀬肇
- Organizer
  日本神経科学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-09-12
- Data Source
  KAKENHI-PROJECT-19700306
[Presentation] Spontaneous calcium activities of astrocytes in vivo differ between cortical layer 1 and layer 2/32007
- Author(s)
  Takata Norio, Hirase Hajime
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-19700306
[Presentation] Spontaneous calcium activities of astrocytes in vivo differ between cortical layer 1 and layer 2/3 (in vivoにおけるアストロサイトの自発的カルシウム活動は大脳皮質の第1層と第2/3層とで異なる)2007
- Author(s)
  高田則雄、平瀬肇
- Organizer
  第30回日本神経科学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-09-02
- Data Source
  KAKENHI-PROJECT-19700306
[Presentation] Spontaneous calcium activities of astrocytes in vivo differ between cortical layer 1 and layer 2/32007
- Author(s)
  高田則雄、平瀬肇
- Organizer
  第36回北米神経科学会
- Place of Presentation
  San Diego, USA
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-19700306
[Presentation] 前脳基底部刺激および感覚刺激はアストロサイトCa2+シグナルとは独立に脳血流変化を起こす
- Author(s)
  高田則雄、永井てるみ、小澤克也、御子柴克彦、平瀬肇
- Organizer
  第３６回日本神経科学会
- Place of Presentation
  京都・国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23700399

1. TAKATA Norio (50415212)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
2. TSUNEKO Mishima (90415307)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. YAHAGI Kazuko

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 酒谷誠一 (40391958)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OZEKI Hirofumi (80553833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. HASHIMOTO Mitsuhiro (90311357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Ishikawa Mami (60212859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 中井淳一 (80237198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 小島比呂志 (50281671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 塚田稔 (80074392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 篠原良章 (10425423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 眞鍋理一郎 (30280837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 今野歩 (40509048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. OHKURA Masamichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 岩井陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 毛内拡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 御子柴克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 三品昌美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIRASE Hajime 平瀬 肇

Research Projects

Research Products

Co-Researchers

神経修飾物質による皮質アストロサイトの中長期的な活動観測と機能的意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Cortical circuit plasticity supported by gliaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Extraction of neurite signals from neuropil calcium signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

生体内で起こる皮質回路シナプス可塑性におけるアストロサイトの役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

皮質回路シナプス可塑性に伴う生体脳神経グリア回路の変化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

哺乳類脳機能の左右差の意義解明のために、左右半球を連絡する原因分子を同定するPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

皮質アストログリア細胞の生体内(イン・ビボ)での動態計測Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HIRASE Hajime 平瀬肇