Nakaoka Yoshikazu 中岡良和

… Alternative Names

NAKAOKA Yoshikazu 中岡良和

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Researcher Number	90393214
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立循環器病研究センター, 研究所, 部長
Affiliation (based on the past Project Information) *help	2015 – 2024: 国立研究開発法人国立循環器病研究センター, 研究所, 部長 2017: 国立研究開発法人国立循環器病研究センター, その他部局等, 研究員 2015: 国立研究開発法人国立循環器病研究センター, その他部局等, その他 2011 – 2014: 大阪大学, 医学(系)研究科(研究院), 助教 2009 – 2012: Osaka University, 医学系研究科, 助教 … More 2011: 大阪大学, 大学院・医学系研究科, 助教 2007 – 2008: Osaka University, 医学系研究科, 特任助教(常勤) 2005 – 2006: 国立循環器病センター(研究所), 循環器形態部, 室員 Less
Review Section/Research Field	Principal Investigator Cardiovascular medicine / Circulatory organs internal medicine / Basic Section 53020:Cardiology-related Except Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine / Basic Section 59010:Rehabilitation science-related / Basic Section 55030:Cardiovascular surgery-related / General physiology / Circulatory organs internal medicine / General pharmacology
Keywords	Principal Investigator 炎症 / 肺動脈性肺高血圧症 / サイトカイン / 肺高血圧症 / IL-21 / interleukin-21 / interleukin-6 / neuregulin-1 / angiopoietin-1 / 心不全 … More / IL-6 / インターロイキン６ / Th17細胞 / 静脈分化 / 冠静脈 / 冠血管 / Neuregulin-1 / インターロイキン21 / インターロイキン6 / レグネース１ / 自己免疫 / リン酸化プロテオミクス / 遺伝子発現解析 / リン酸化プロテオーム解析 / ChIPseq解析 / リン酸化プロテオーム / アリルハイドロカーボン受容体 / 叢状病変 / 血管保護 / エンドセリン受容体拮抗薬 / 血管リモデリング / インターロイキン２１ / 炎症性サイトカイン / 肺動脈性肺高血圧症（PAH) / トランスジェニックマウス / 高安動脈炎 / インターロイキン６受容体抗体 / interleukin-6受容体抗体 / M2マクロファージ / 血管成熟化 / 動脈 / 静脈 / APJ / COUP-TFII / 心筋梗塞 / 血管新生 / 冠動脈 / アンジオポイエチン１ / 血管形成 / 内皮細胞 / 静脈洞 / アイソフォーム / サルコメア / ドッキングタンパク質 / Gab1 / ErbB / 心外膜 / 心内膜内皮 / 心筋-内皮細胞間相互作用 / Tie2 / 静動洞 / EphB4 / パラクラインシグナル / 内皮 / 心筋 / 心内膜線維弾性症 / Gabファミリー蛋白質 / 心内膜弾性繊維症 / Gab ファミリー蛋白質 / 心筋-内皮相互作用 / Angiopoietin-1 / 心内膜弾性線維症 / MAPキナーゼ / 酸化ストレス / Gabファミリー … More Except Principal Investigator 肺高血圧症 / 肺動脈性肺高血圧症 / バイオマーカー / 炎症 / 循環器・高血圧 / サイトカイン / 心不全 / 腸内細菌叢 / 摂食嚥下障害 / 脳卒中 / サルコペニア / 脊髄障害 / shaggy aorta / インターロイキンー６ / 芳香族炭化水素受容体 / 転写因子 / IL-6阻害薬 / 腸内細菌 / 高安動脈炎 / 大型血管炎 / 右心不全 / ヘルパーT細胞 / Interleukin-6 / 血管リモデリング / 肺血管リモデリング / 炎症性サイトカイン / interleukin-6 / 芳香族環状炭化水素受容体 / 組織特異的遺伝子欠損マウス / アリルハイドロカーボン受容体 / 心疾患 / 妊娠高血圧症候群 / 妊娠・出産 / 周産期心筋症 / 間歇的低酸素 / 肺交感神経 / マクロファージ / 肺高血圧 / 生理学 / 免疫学 / TrkB / 高血圧 / 血管新生阻害薬 / 蛋白尿 / 高血圧症 / 分子標的薬 / 心毒性 / 腫瘍循環器 / KLF4 / トランスジェニックマウス / KLF2 / Gab1 / 内皮 / 血管炎症 / 動脈硬化 / 心血管・血液 Less

AIによるステントグラフト内挿術後の脊髄障害発生予測モデル構築とバイオマーカー探索
- Principal Investigator
  
  清家愛幹
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  National Cardiovascular Center Research Institute
肺動脈性肺高血圧症における芳香族炭化水素受容体とIL-6シグナルのクロストークの解明
- Principal Investigator
  
  岡澤慎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
Elucidating the molecular pathogenesis of CTD-associated PAHPrincipal Investigator
- Principal Investigator
  
  中岡良和
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
Construction of an evaluation system for feeding and swallowing disorders and sarcopenia after stroke and search for key molecules in the brain-gut-muscle linkage
- Principal Investigator
  
  猪原匡史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  National Cardiovascular Center Research Institute
The Pathogenesis of pulmonary arterial hypertension via aryl hydrocarbon receptorPrincipal Investigator
- Principal Investigator
  
  Nakaoka Yoshikazu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
Investigation of the pathogenesis of pulmonary arterial hypertension using tissue-specific Ahr knockout mice
- Principal Investigator
  
  Okazawa Makoto
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
高安動脈炎に関連する肺高血圧症に対するIL-6阻害薬の有効性と治療指標の探索
- Principal Investigator
  
  上田仁
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
Fundamental research for the development of a new strategy for the treatment of severe pulmonary hypertension by IL-6 blockade
- Principal Investigator
  
  Inagaki Tadakatsu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
Investigation of the pathogenesis of pulmonary hypertension through inflammatory signaling by TrkB in bronchial epithelial cells
- Principal Investigator
  
  Makoto Okazawa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  National Cardiovascular Center Research Institute
Role of pulmonary sympathetic nerves in the regulation of the pulmonary circulation by beta-receptors on pulmonary macrophages during chronic intermittent hypoxia
- Principal Investigator
  
  SHIRAI Mikiyasu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  National Cardiovascular Center Research Institute
Elucidation of the molecular pathogenesis of pulmonary hypertension via inflammatory cytokinesPrincipal Investigator
- Principal Investigator
  
  NAKAOKA YOSHIKAZU
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  National Cardiovascular Center Research Institute
Molecular mechanism of Vasculitis and Pulmonary arterial hypertension via inflammatory cytokinesPrincipal Investigator
- Principal Investigator
  
  Nakaoka Yoshikazu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular medicine
- Research Institution
  National Cardiovascular Center Research Institute
Biomarker research of peripartum cardiomyopathy with hypertensive disorders in pregnancy
- Principal Investigator
  
  Kamiya Chizuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  National Cardiovascular Center Research Institute
Evaluation of cardiotoxicity and elucidation of cardiotoxic molecular mechanisms in cancer patients receiving angiogenesis inhibitors
- Principal Investigator
  
  Shioyama Wataru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
Angiopoietin-1-mediated vascular development and maturation in the developing heartPrincipal Investigator
- Principal Investigator
  
  NAKAOKA YOSHIKAZU
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  National Cardiovascular Center Research Institute
  Osaka University
The novel therapeutic strategy for pulmonary hypertension targeting inflammation amplification loop mediated by IL-6Principal Investigator
- Principal Investigator
  
  NAKAOKA YOSHIKAZU
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
The role of sarcomere-specific isoform of docking protein Gab1in heart failurePrincipal Investigator
- Principal Investigator
  
  NAKAOKA Yoshikazu
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Myocardial inflammation of heart failure as a novel therapeutic target
- Principal Investigator
  
  FUJIO Yasushi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University
The molecular mechanism of atherosclerosis through endothelial dysfunction
- Principal Investigator
  
  KURODA TADASHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
  Osaka University
The signaling network between endothelium and myocardium responsible for myocardial protectionPrincipal Investigator
- Principal Investigator
  
  NAKAOKA Yoshikazu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
The role of paracrine signal networks between myocardium and endothelium in the prevention of heart failurePrincipal Investigator
- Principal Investigator
  
  NAKAOKA Yoshikazu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
心血管系でのGabファミリー蛋白質の機能解析Principal Investigator
- Principal Investigator
  
  中岡良和
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Cardiovascular Center Research Institute

[Book] Cutting Edge of Molecular Cardiology 新しい臨床を開拓するための分子循環器病学2019
- Author(s)
  中岡良和（小室一成編集）
- Total Pages
  7
- Publisher
  南山堂
- ISBN
  9784525249410
- Data Source
  KAKENHI-PROJECT-16H05298
[Book] 免疫・炎症病態×治療研究Update　 Physician Scientistが拓く世界2019
- Author(s)
  中岡良和（熊ノ郷淳編集）
- Total Pages
  8
- Publisher
  南山堂
- ISBN
  9784525167813
- Data Source
  KAKENHI-PROJECT-16H05298
[Book] 臨床脈管学（日本脈管学会編集）2017
- Author(s)
  中岡良和
- Total Pages
  5
- Publisher
  日本医学出版
- ISBN
- Data Source
  KAKENHI-PROJECT-16H05298
[Book] Annual Review 2016循環器2016
- Author(s)
  中岡良和
- Total Pages
  8
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25293183
[Book] Annual Review 2016循環器2016
- Author(s)
  中岡良和
- Total Pages
  8
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K15309
[Book] Annual Review ２０１６循環器2016
- Author(s)
  中岡良和
- Total Pages
  8
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K15309
[Book] 循環器病研究の進歩2016
- Author(s)
  中岡良和
- Total Pages
  7
- Publisher
  協和企画
- Data Source
  KAKENHI-PROJECT-15K15309
[Book] 循環器病研究の進歩　2016年第３７巻第１号2016
- Author(s)
  中岡良和
- Total Pages
  7
- Publisher
  協和企画
- Data Source
  KAKENHI-PROJECT-16H05298
[Book] Ａｎｎｕａｌ　Ｒｅｖｉｅｗ　2016 循環器2016
- Author(s)
  中岡良和
- Total Pages
  8
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-16H05298
[Book] 血管新生研究の最先端　（8章２）Angiopoietin/Tie受容体）2013
- Author(s)
  中岡良和
- Total Pages
  331
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-24659391
[Book] 血管新生研究の最先端2013
- Author(s)
  中岡良和
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-24659391
[Book] 血管生物医学事典(分担執筆:3項目合計9ページ)2011
- Author(s)
  中岡良和、小室一成
- Total Pages
  489
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-21590930
[Book] 血管生物医学事典2011
- Author(s)
  小室一成・中岡良和, 他
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-21590930
[Book] 血管生物医学事典(日本血管生物医学会編集、分担執筆)2011
- Author(s)
  小室一成・中岡良和. 他
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23591101
[Book] サイトカインシグナルによる心不全の制御機構2008
- Author(s)
  瀧原圭子、中岡良和
- Total Pages
  5
- Publisher
  心臟日本心臟財団
- Data Source
  KAKENHI-PROJECT-19590844
[Book] 心血管系の情報伝達の概観と心血管系に特徴的なメカノシグナル(分子メカニズムから解き明する疾患のサイエンス)(実験医学増刊)2006
- Author(s)
  中岡良和
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-17790518
[Book] 核医学以外の分子イメージングの現在と将来2005
- Author(s)
  中岡良和
- Total Pages
  4
- Publisher
  Heart Vierw(ハートビュー)メジカルビュー社
- Data Source
  KAKENHI-PROJECT-17790518
[Journal Article] IL-6/gp130 signaling in CD4+ T cells drives the pathogenesis of pulmonary hypertension.2024
- Author(s)
  Ishibashi T, Inagaki T, Okazawa M, Yamagishi A, Ohta-Ogo K, Asano R, Masaki T, Kotani Y, Ding X, Chikaishi-Kirino T, Maedera N, Shirai M, Hatakeyama K, Kubota Y, Kishimoto T, Nakaoka Y.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 121 Issue: 16
- DOI
  10.1073/pnas.2315123121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08144, KAKENHI-PROJECT-21K08070, KAKENHI-PROJECT-23K27605
[Journal Article] Organ Damage and Quality of Life in Takayasu Arteritis　― Evidence From a National Registry Analysis ―2024
- Author(s)
  Yoshifuji Hajime、Nakaoka Yoshikazu、Uchida Haruhito A.、Sugihara Takahiko、Watanabe Yoshiko、Funakoshi Sohei、Isobe Mitsuaki、Harigai Masayoshi、Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis (JPVAS)
- Journal Title
  
  Circ J
  
  Volume: 88 Issue: 3 Pages: 285-294
- DOI
  10.1253/circj.CJ-23-0656
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2024-02-22
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27605
[Journal Article] Demographic Traits, Clinical Status, and Comorbidities of Patients With Thromboangiitis Obliterans in Japan2024
- Author(s)
  Watanabe Yoshiko、Shimizu Yuuki、Hashimoto Takuya、Iwahashi Toru、Shigematsu Kunihiro、Nakaoka Yoshikazu、Harigai Masayoshi、Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis (JPVAS)
- Journal Title
  
  Circ J
  
  Volume: 88 Issue: 3 Pages: 319-328
- DOI
  10.1253/circj.CJ-23-0211
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2024-02-22
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27605
[Journal Article] Current Immunosuppressive Treatment for Takayasu Arteritis2024
- Author(s)
  Arita Yoh、Ishibashi Tomohiko、Nakaoka Yoshikazu
- Journal Title
  
  Circ J
  
  Volume: 88 Issue: 10 Pages: 1605-1609
- DOI
  10.1253/circj.CJ-23-0780
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2024-09-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08070, KAKENHI-PROJECT-23K27605
[Journal Article] A multicentre, large-scale, observational study of?tocilizumab in?patients with giant cell arteritis in?Japan2023
- Author(s)
  Harigai Masayoshi、Miyamae Takako、Hashimoto Hideyuki、Umetsu Kosei、Yamashita Katsuhisa、Nakaoka Yoshikazu
- Journal Title
  
  Modern Rheumatology
  
  Volume: - Issue: 4 Pages: 775-783
- DOI
  10.1093/mr/road074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K27605
[Journal Article] Establishing clinical remission criteria for?giant cell arteritis: Results of?a Delphi exercise carried out by an expert panel of?the Japan Research Committee of?the Ministry of?Health, Labour, and?Welfare for?Intractable?Vasculitis2023
- Author(s)
  Sugihara Takahiko、Yoshifuji Hajime、Uchida Haruhito A、Maejima Yasuhiro、Watanabe Yoshiko、Tanemoto Kazuo、Umezawa Natsuka、Manabe Yusuke、Ishizaki Jun、Shirai Tsuyoshi、Nagafuchi Hiroko、Hasegawa Hitoshi、Niiro Hiroaki、Ishii Tomonori、Nakaoka Yoshikazu、Harigai Masayoshi
- Journal Title
  
  Modern Rheumatology
  
  Volume: 34 Issue: 3 Pages: 568-575
- DOI
  10.1093/mr/road046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08469, KAKENHI-PROJECT-23K27605
[Journal Article] Evaluation of right coronary vascular dysfunction in severe pulmonary hypertensive rats using synchrotron radiation microangiography2021
- Author(s)
  Inagaki Tadakatsu、Pearson James T.、Tsuchimochi Hirotsugu、Schwenke Daryl O.、Saito Shigeyoshi、Higuchi Takahiro、Masaki Takeshi、Umetani Keiji、Shirai Mikiyasu、Nakaoka Yoshikazu
- Journal Title
  
  American Journal of Physiology-Heart and Circulatory Physiology
  
  Volume: 320 Issue: 3 Pages: H1021-H1036
- DOI
  10.1152/ajpheart.00327.2020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08506
[Journal Article] Aryl hydrocarbon receptor is essential for the pathogenesis of pulmonary arterial hypertension2021
- Author(s)
  Masaki T, Okazawa M, Asano R, Inagaki T, Ishibashi T, Yamagishi A, Umeki-Mizushima S, Nishimura M, Manabe Y, Ishibashi-Ueda H, Shirai M, Tsuchimochi H, Pearson JT, Kumanogoh A, Sakata Y, Ogo T, Kishimoto T, Nakaoka Y
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 118 Issue: 11
- DOI
  10.1073/pnas.2023899118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17622, KAKENHI-PROJECT-20K17137, KAKENHI-PROJECT-19K08506
[Journal Article] Pristane/Hypoxia (PriHx) Mouse as a Novel Model of Pulmonary Hypertension Reflecting Inflammation and Fibrosis2020
- Author(s)
  Mori Hiroyoshi、Ishibashi Tomohiko、Inagaki Tadakatsu、Okazawa Makoto、Masaki Takeshi、Asano Ryotaro、Manabe Yusuke、Ohta-Ogo Keiko、Narazaki Masashi、Ishibashi-Ueda Hatsue、Kumanogoh Atsushi、Nakaoka Yoshikazu
- Journal Title
  
  Circ J
  
  Volume: 84 Issue: 7 Pages: 1163-1172
- DOI
  10.1253/circj.CJ-19-1102
- NAID
  130007864283
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2020-06-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08506, KAKENHI-PROJECT-20K17137, KAKENHI-PROJECT-17K10002, KAKENHI-PROJECT-19K17622
[Journal Article] Beta Cell-Derived Angiopoietin-1 Regulates Insulin Secretion and Glucose Homeostasis by Stabilizing Islet Microenvironment.2019
- Author(s)
  1.Park HS, Kim HZ, Park JS, Lee J, Lee SP, Kim H, Ahn CW, Nakaoka Y, Koh GY, Kang S.
- Journal Title
  
  Diabetes
  
  Volume: 68(4) Issue: 4 Pages: 774-786
- DOI
  10.2337/db18-0864
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05126, KAKENHI-PROJECT-16H05298
[Journal Article] 心筋―内皮細胞間クロストークによる心臓の発生・恒常性維持の制御機構－Neuregulin-1/ErbBシグナルを中心に.2019
- Author(s)
  中岡良和
- Journal Title
  
  実験医学
  
  Volume: 37(5) Pages: 751-758
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] 高安動脈炎と巨細胞性動脈炎2019
- Author(s)
  中岡良和
- Journal Title
  
  日本臨牀
  
  Volume: 77(3) Pages: 522-530
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] Efficacy and safety of tocilizumab in patients with refractory Takayasu arteritis: results from a randomised, double-blind, placebo-controlled, phase 3 trial in Japan (the TAKT study).2018
- Author(s)
  2.Nakaoka Y, Isobe M, Takei S, Tanaka Y, Ishii T, Yokota S, Nomura A, Yoshida S, Nishimoto N.
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: 77 Issue: 3 Pages: 348-354
- DOI
  10.1136/annrheumdis-2017-211878
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] Response to: 'Efficacy and safety of tocilizumab in patients with refractory Takayasu arteritis' by Lee and Song.2018
- Author(s)
  Nakaoka Y.
- Journal Title
  
  Ann Rheum Dis.
  
  Volume: in press Issue: 1 Pages: e10-e10
- DOI
  10.1136/annrheumdis-2017-212871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] 大型血管炎の治療ガイドライン（高安動脈炎・巨細胞性動脈炎）．2018
- Author(s)
  中岡良和
- Journal Title
  
  炎症と免疫
  
  Volume: 26(1) Pages: 25-32
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] 心不全の分子機序、炎症、サイトカイン.2018
- Author(s)
  中岡良和
- Journal Title
  
  日本臨牀
  
  Volume: 76(Suppl 9) Pages: 162-168
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.2018
- Author(s)
  Terao C, Yoshifuji H, Matsumura T, Naruse TK, Ishii T, Nakaoka Y, Kirino Y, Matsuo K, Origuchi T, Shimizu M, Maejima Y, Amiya E, Tamura N, Kawaguchi T, Takahashi M, Setoh K, Ohmura K, Watanabe R, Horita T, Atsumi T, Matsukura M, Miyata T, et al.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 115 Issue: 51 Pages: 13045-13050
- DOI
  10.1073/pnas.1808850115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09975, KAKENHI-PROJECT-16H05298, KAKENHI-PROJECT-18H02926, KAKENHI-PROJECT-16H06277
[Journal Article] 肺高血圧症と炎症.2018
- Author(s)
  中岡良和
- Journal Title
  
  別冊BIO Clinica.　慢性炎症と疾患「心臓と血管の慢性炎症」
  
  Volume: 7（１） Pages: 49-53
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] 高安動脈炎の治療（TAKT試験結果を含めて）2018
- Author(s)
  中岡良和
- Journal Title
  
  日本臨牀　　76(Suppl 6),112-119, 2018
  
  Volume: 76(Suppl 6) Pages: 112-119
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] Myocardial Angiopoietin-1 Controls Atrial Chamber Morphogenesis by Spatiotemporal Degradation of Cardiac Jelly2018
- Author(s)
  Kim Kyun Hoo、Nakaoka Yoshikazu、Augustin Hellmut G.、Koh Gou Young
- Journal Title
  
  Cell Reports
  
  Volume: 23 Issue: 8 Pages: 2455-2466
- DOI
  10.1016/j.celrep.2018.04.080
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] Fibrosis Through Activation of PKA Signaling in Hypertrophired Heart.2017
- Author(s)
  Wang Q,Oka T,Yamagami K,Lee JK,Akazawa H,Naito AT,Yasui T,Ishizu T,Nakaoka Y,Sakata Y,Komuro I.
- Journal Title
  
  International Heart Journal
  
  Volume: 58 Pages: 107-114
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15309
[Journal Article] An EP4 Receptor Agonist Inhibits Cardiac Fibrosis Through Activation of PKA Signaling in Hypertrophied Heart2017
- Author(s)
  Wang Q,Oka T,Yamagami K,Lee JK,Akazawa H,Naito AT,Yasui T,Ishizu T,Nakaoka Y,Sakata Y,Komuro I.
- Journal Title
  
  Int. Heart J.
  
  Volume: 58 Issue: 1 Pages: 107-114
- DOI
  10.1536/ihj.16-200
- NAID
  130005330538
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] 高安動脈炎.2017
- Author(s)
  中岡良和
- Journal Title
  
  日本医師会雑誌. 生涯教育シリーズ(92) 脳血管障害診療のエッセンス．
  
  Volume: S146（１）
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] Widespread Coronary Dysfunction in the Absence of HDL Receptor SR-B1 in an Ischemic Cardiomyopathy Mouse Model.2017
- Author(s)
  Pearson JT, Yoshimoto M, Chen YC, Sultani R, Edgley AJ, Nakaoka H, Nishida M, Umetani K, Waddingham MT, Jin HL, Zhang Y, Kelly DJ, Schwenke DO, Inagaki T, Tsuchimochi H, Komuro I, Yamashita S, Shirai M.
- Journal Title
  
  Sci Rep
  
  Volume: Dec 22;7(1) Issue: 1 Pages: 18108-18108
- DOI
  10.1038/s41598-017-18485-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16033, KAKENHI-INTERNATIONAL-15K21716, KAKENHI-PROJECT-16H05126, KAKENHI-PROJECT-17H02100, KAKENHI-PROJECT-16K15452
[Journal Article] Gab1 adaptor protein acts as a gatekeeper to balance hepatocyte death and proliferation during acetaminophen-induced liver injury in mice.2016
- Author(s)
  Furuta K, Yoshida Y, Ogura S, Kurahashi T, Kizu T, Maeda S, Egawa M, Chatani N, Nishida K, Nakaoka Y, Kiso S, Kamada Y, Takehara T.
- Journal Title
  
  Hepatology
  
  Volume: 63 Issue: 4 Pages: 1340-1355
- DOI
  10.1002/hep.28410
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15309, KAKENHI-PROJECT-25293183, KAKENHI-PROJECT-15H04810, KAKENHI-PROJECT-16H05298, KAKENHI-PROJECT-26461001, KAKENHI-PROJECT-15K08997, KAKENHI-PROJECT-16K15428, KAKENHI-PROJECT-16K19341
[Journal Article] 大型血管炎に対する抗Interleukin-6受容体抗体療法2016
- Author(s)
  中岡良和
- Journal Title
  
  最新医学
  
  Volume: 71 Pages: 2334-2343
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] 肺高血圧症におけるサイトカインネットワーク．2016
- Author(s)
  中岡良和
- Journal Title
  
  分子呼吸器病
  
  Volume: 20 Pages: 73-76
- Data Source
  KAKENHI-PROJECT-25293183
[Journal Article] 肺高血圧症におけるサイトカインネットワーク．分子呼吸器病2016
- Author(s)
  中岡良和
- Journal Title
  
  分子呼吸器病
  
  Volume: 20 Pages: 73-76
- Data Source
  KAKENHI-PROJECT-15K15309
[Journal Article] Ｉｎｔｅｒｌｅｕｋｉｎ－６による肺高血圧症の病態形成機構2016
- Author(s)
  中岡良和
- Journal Title
  
  医学のあゆみ
  
  Volume: 257 Pages: 248-249
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] IL-6抗体医薬による大型血管炎の治療2016
- Author(s)
  中岡良和
- Journal Title
  
  循環器内科
  
  Volume: 80 Pages: 296-303
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] ＥｒｂＢ／ＨＥＲシグナルの分子標的薬による心毒性2016
- Author(s)
  中岡良和
- Journal Title
  
  ＣＡＲＤＩＡＣ　ＰＲＡＣＴＩＣＥ
  
  Volume: 27 Pages: 91-98
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] 炎症性シグナルによる肺高血圧症の病態制御と治療2016
- Author(s)
  中岡良和
- Journal Title
  
  血管医学
  
  Volume: 17 Pages: 249-255
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] Molecular Characterization of Striated Muscle-specific Gab1Isoform as aCritical Signal Transducer for Neuregulin-1/ErbB Signaling in Cardiomyocytes.2016
- Author(s)
  Yasui T,Masaki T,Arita Y,Ishibashi T,Inagaki T,Okazawa M,Oka T,Shioyama W,Yamauchi-Takihara K,Komuro I,Sakata Y,Nakaoka Y.
- Journal Title
  
  PlosOne
  
  Volume: 11 Issue: 11 Pages: e0166710-e0166710
- DOI
  10.1371/journal.pone.0166710
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05298, KAKENHI-PROJECT-15K15309, KAKENHI-PROJECT-15K01712
[Journal Article] 高安動脈炎・耳鼻咽喉科・頭頸部外科2016
- Author(s)
  中岡良和
- Journal Title
  
  耳鼻咽喉科処方マニュアル
  
  Volume: 88 Pages: 187-189
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] 高安動脈炎に対するIL-6阻害療法2016
- Author(s)
  中岡良和
- Journal Title
  
  医学のあゆみ
  
  Volume: 257 Pages: 319-321
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] Amelioration of sepsis by TIE2 activation-induced vascular protection.2016
- Author(s)
  Han S,Lee SJ,Kim KE,Lee HS,Oh N,Park I,Ko E,Oh SJ,Kim HC,Kim SKim SH,Kim C,Nakaoka Y,He Y,Augustin HG,Hu J,Song PH,Kim YI,Kim P,Kim I,Koh GY.
- Journal Title
  
  Science Translation Medicine
  
  Volume: 8 Issue: 335 Pages: 335-355
- DOI
  10.1126/scitranslmed.aad9260
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05298, KAKENHI-PROJECT-15K15309
[Journal Article] 大型血管炎に対する薬物療法2016
- Author(s)
  中岡良和
- Journal Title
  
  医学のあゆみ
  
  Volume: 259 Pages: 1336-1342
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] 冠動脈と冠静脈の形成機序の違い2016
- Author(s)
  中岡良和,有田陽
- Journal Title
  
  日本臨床
  
  Volume: 74 Pages: 67-73
- Data Source
  KAKENHI-PROJECT-16H05298
[Journal Article] 高安動脈炎と抗IL-6受容体療法．2015
- Author(s)
  中岡良和
- Journal Title
  
  感染　炎症　免疫
  
  Volume: 45 Pages: 262-265
- Data Source
  KAKENHI-PROJECT-25293183
[Journal Article] 高安動脈炎と抗IL-6受容体療法2015
- Author(s)
  中岡良和
- Journal Title
  
  感染　炎症　免疫
  
  Volume: 45 Pages: 262-265
- Data Source
  KAKENHI-PROJECT-15K15309
[Journal Article] Loss of Gab1 adaptor protein in hepatocytes aggravates experimental liver fibrosis in mice.2015
- Author(s)
  Kizu T, Yoshida Y, Furuta K, Ogura S, Egawa M, Chatani N, Hamano M, Takemura T, Ezaki H, Kamada Y, Nishida K, Nakaoka Y, Kiso S, Takehara T.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 308 Issue: 7 Pages: 613-624
- DOI
  10.1152/ajpgi.00289.2014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590972, KAKENHI-PROJECT-24590975, KAKENHI-PROJECT-25670386, KAKENHI-PROJECT-26461001, KAKENHI-PROJECT-25293183, KAKENHI-PROJECT-15H04810
[Journal Article] Gab1 Is Modulated by Chronic Hypoxia in Children with Cyanotic Congenital Heart Defect and Its Overexpression Reduces Apoptosis in Rat Neonatal Cardiomyocytes.2015
- Author(s)
  Cherif M., Caputo M, Nakaoka Y, Angelini G, Ghorbel M.
- Journal Title
  
  BioMed Research International.
  
  Volume: 101155 Pages: 718492-718492
- DOI
  10.1155/2015/718492
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15309, KAKENHI-PROJECT-25293183
[Journal Article] 高安動脈炎2015
- Author(s)
  中岡良和
- Journal Title
  
  循環器内科
  
  Volume: 78 Pages: 366-373
- Data Source
  KAKENHI-PROJECT-15K15309
[Journal Article] Loss of Gab1 adaptor protein in hepatocytes aggravates experimental liver fibrosis in mice.2015
- Author(s)
  Kizu T, Yoshida Y, Furuta K, Ogura S, Egawa M, Chatani N, Hamano M, Takemura T, Ezaki H, Kamada Y, Nishida K, Nakaoka Y, Kiso S, Takehara T.
- Journal Title
  
  American journal of physiology.Gastrointestinal and liver physiology.
  
  Volume: 308
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15309
[Journal Article] IL-6による肺高血圧症の病態形成の分子機構．2015
- Author(s)
  中岡良和
- Journal Title
  
  Pulmonary Hypertension Update
  
  Volume: 1 Pages: 62-67
- Data Source
  KAKENHI-PROJECT-25293183
[Journal Article] IL-6による肺高血圧症の病態形成の分子機構2015
- Author(s)
  中岡良和
- Journal Title
  
  Pulmonary Hypertension Update
  
  Volume: 1 Pages: 62-67
- Data Source
  KAKENHI-PROJECT-15K15309
[Journal Article] Cytokine storm after cessation of tocilizumab in a patient with refractory Takayasu arteritis.2015
- Author(s)
  Arita Y, Nakaoka Y, Otsuki M, Higuchi K, Hashimoto-Kataoka T, Yasui T, Masaki T, Ohtani T, Kishimoto T, Yamauchi-Takihara K, Komuro I, Sakata Y.
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 187 Pages: 319-321
- DOI
  10.1016/j.ijcard.2015.03.399
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670386, KAKENHI-PROJECT-15K01712, KAKENHI-PROJECT-15K15309, KAKENHI-PROJECT-25293183
[Journal Article] Takayasu arteritis and ulcerative colitis -high concurrence ratio and genetic overlap.2015
- Author(s)
  Terao C, Matsumura T, Yoshifuji H, Kirino Y, Maejima Y, Kochi Y, Ogimoto A, Yamamoto M, Takahashi H, Nakayamada S, Saito K, Wada Y, Narita I, Kawaguchi Y, Yamanaka H, Ohmura K, Atsumi T, Tanemoto K, Miyata T, Kuwana M, Komuro I, Tabara Y, Ueda A, Isobe M, Mimori T, Matsuda F.
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: - Issue: 8 Pages: 2226-2232
- DOI
  10.1002/art.39157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670399, KAKENHI-PROJECT-26713036, KAKENHI-PROJECT-15K15309, KAKENHI-PROJECT-24591436, KAKENHI-PROJECT-26461072, KAKENHI-PROJECT-25293141, KAKENHI-PROJECT-25293183
[Journal Article] Interleukin-6/interleukin-21 signaling axis is critical in the pathogenesis of pulmonary arterial hypertension2015
- Author(s)
  Hashimoto-Kataoka T, Hosen N, Sonobe T, Arita Y, Yasui T, Masaki T, Minami M, Inagaki T, Miyagawa S, Sawa Y, Murakami M, Kumanogoh A, Yamauchi-Takihara K, Okumura M, Kishimoto T, Komuro I, Shirai M, Sakata Y, and Nakaoka Y
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: Early Edition Issue: 20 Pages: 1-10
- DOI
  10.1073/pnas.1424774112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860184, KAKENHI-PROJECT-15K01712, KAKENHI-PROJECT-15K15309, KAKENHI-PROJECT-26670413, KAKENHI-PROJECT-25293183
[Journal Article] 高安動脈炎．2015
- Author(s)
  中岡良和
- Journal Title
  
  循環器内科
  
  Volume: 78 Pages: 366-373
- Data Source
  KAKENHI-PROJECT-25293183
[Journal Article] 野本論文に対するEditorial Comment-難治性高安動脈炎に対する抗ＩＬ-6レセプター抗体Tocilizumabの有効性について2014
- Author(s)
  中岡良和
- Journal Title
  
  心臓
  
  Volume: 46 Pages: 1592-1593
- NAID
  130005113470
- Data Source
  KAKENHI-PROJECT-25670386
[Journal Article] Neureguiln-1/ErbBシグナルの心血管系における生理機能2014
- Author(s)
  中岡良和
- Journal Title
  
  医学のあゆみ
  
  Volume: 250 Pages: 200-206
- Data Source
  KAKENHI-PROJECT-25293183
[Journal Article] Neureguiln-1/ErbBシグナルの心血管系における生理機能2014
- Author(s)
  中岡良和
- Journal Title
  
  医学のあゆみ
  
  Volume: 250 Pages: 200-206
- Data Source
  KAKENHI-PROJECT-25670386
[Journal Article] Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity.2014
- Author(s)
  Park DY, Lee J, Park I, Choi D, Lee S, Song S, Hwang Y, Hong KY, Nakaoka Y, Makinen T, Kim P, Alitalo K, Hong YK, Koh GY.
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 24 Issue: 9 Pages: 3960-74
- DOI
  10.1172/jci75392
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293183, KAKENHI-PROJECT-25670386
[Journal Article] Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart2014
- Author(s)
  Arita Y, Nakaoka Y, Matsunaga T, Kidoya H, Yamamizu K, Arima Y, Kataoka-Hashimoto T, Ikeoka K, Yasui T, Masaki T, Yamamoto K, Higuchi K, Park JS, Shirai M, Nishiyama K, Yamagishi H, Otsu K, Kurihara H, Minami T, Yamauchi-Takihara K, Koh GY, Mochizuki N, Takakura N, Sakata Y, Yamashita JK, Komuro I
- Journal Title
  
  Nat Commun
  
  Volume: 5 Issue: 1 Pages: 4452-4452
- DOI
  10.1038/ncomms5552
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22112005, KAKENHI-PROJECT-24300330, KAKENHI-PUBLICLY-25111705, KAKENHI-PUBLICLY-25122710, KAKENHI-PROJECT-25293183, KAKENHI-PROJECT-25293238, KAKENHI-PROJECT-25670386, KAKENHI-PROJECT-26290035, KAKENHI-PROJECT-26640069, KAKENHI-PROJECT-26670394, KAKENHI-PROJECT-26670396, KAKENHI-PROJECT-24249047
[Journal Article] 大型血管炎の標準治療2014
- Author(s)
  中岡良和
- Journal Title
  
  Modern Physician～臨床医のための血管炎の知識up-to-date
  
  Volume: 34 Pages: 1034-1039
- Data Source
  KAKENHI-PROJECT-25293183
[Journal Article] 大型血管炎の標準治療2014
- Author(s)
  中岡良和
- Journal Title
  
  Modern Physician～臨床医のための血管炎の知識up-to-date
  
  Volume: 34 Pages: 1034-1039
- Data Source
  KAKENHI-PROJECT-25670386
[Journal Article] 野本論文に対するEditorial Comment-難治性高安動脈炎に対する抗IL-6レセプター抗体Tocilizumabの有効性について2014
- Author(s)
  中岡良和
- Journal Title
  
  心臓
  
  Volume: 46 Pages: 1592-1593
- NAID
  130005113470
- Data Source
  KAKENHI-PROJECT-25293183
[Journal Article] 高安動脈炎の診断と治療2013
- Author(s)
  中岡良和
- Journal Title
  
  医学のあゆみ(血管炎の診断と治療)
  
  Volume: 246 (1) Pages: 5-11
- Data Source
  KAKENHI-PROJECT-23591101
[Journal Article] Angiopoietin-1 Suppresses Choroidal Neovascularization and Vascular Leakage.2013
- Author(s)
  Lee J, Park DY, Park DY, Park I, Chang W, Nakaoka Y, Komuro I, Yoo OJ, Koh GY.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: in press Issue: 4 Pages: 2191-2199
- DOI
  10.1167/iovs.14-13897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591101, KAKENHI-PROJECT-25293183, KAKENHI-PROJECT-25670386
[Journal Article] 高安動脈炎の診断と治療 -生物学的製剤による治療の現状に焦点を当てて2013
- Author(s)
  中岡良和
- Journal Title
  
  医学のあゆみ
  
  Volume: 246 Pages: 5-11
- Data Source
  KAKENHI-PROJECT-25670386
[Journal Article] 高安動脈炎の診断と治療 -生物学的製剤による治療の現状に焦点を当てて2013
- Author(s)
  中岡良和
- Journal Title
  
  医学のあゆみ
  
  Volume: 246 Pages: 5-11
- Data Source
  KAKENHI-PROJECT-23591101
[Journal Article] 大型血管炎―高安病を中心に2013
- Author(s)
  中岡良和
- Journal Title
  
  臨床検査
  
  Volume: 57 Pages: 298-305
- Data Source
  KAKENHI-PROJECT-24659391
[Journal Article] Tocilizumab for the treatment of patients with refractory takayasu arteritis.2013
- Author(s)
  Nakaoka Y, Higuchi K, Arita Y, Otsuki M, Yamamoto K, Hashimoto-Kataoka T, Yasui T, Ikeoka K, Ohtani T, Sakata Y, Shima Y, Kumanogoh A, Yamauchi-Takihara K, Tanaka T, Kishimoto T, Komuro I.
- Journal Title
  
  International Heart Journal
  
  Volume: 54 Pages: 405-411
- NAID
  130003383361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293183
[Journal Article] 血管リモデリング2013
- Author(s)
  中岡良和、小室一成
- Journal Title
  
  日本医師会雑誌(特別号・高血圧診療のすべて)
  
  Volume: 142(Suppl 1)
- Data Source
  KAKENHI-PROJECT-23591101
[Journal Article] 影山論文に対するEditorial Comment - 冠動脈・大動脈疾患を合併する巨細胞性動脈炎では厳密な慢性炎症のコントロールに留意する必要がある2013
- Author(s)
  中岡良和
- Journal Title
  
  心臓
  
  Volume: 45 Pages: 1293-1294
- NAID
  130004716912
- Data Source
  KAKENHI-PROJECT-25670386
[Journal Article] 影山論文に対するEditorial Comment - 冠動脈・大動脈疾患を合併する巨細胞性動脈炎では厳密な慢性炎症のコントロールに留意する必要がある2013
- Author(s)
  中岡良和
- Journal Title
  
  心臓
  
  Volume: 45 Pages: 1293-1294
- NAID
  130004716912
- Data Source
  KAKENHI-PROJECT-23591101
[Journal Article] 大型血管炎-高安病を中心に2013
- Author(s)
  中岡良和
- Journal Title
  
  臨床検査
  
  Volume: 57 Pages: 298-305
- Data Source
  KAKENHI-PROJECT-24659391
[Journal Article] Tocilizumab for the Treatment of the Patients with Refractory Takayasu Arteritis2013
- Author(s)
  Nakaoka Yoshikazu, Higuchi Kaori, Arita Yoh, Otsuki Michio, Yamamoto Kaori, Hashimoto-Kataoka Takahiro, Yasui Taku, Ikeoka Kuniyasu, Ohtani Tomohito, Sakata Yasushi, Shima Yoshihito, Kumanogoh Atsushi, Yamauchi-Takihara Keiko, Tanaka Toshio, Kishimoto Tadamitsu, Komuro Issei
- Journal Title
  
  International Heart Journal
  
  Volume: 54 Pages: 405-411
- NAID
  130003383361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591101
[Journal Article] Interleukin-6 シグナル制御による肺動脈性肺高血圧症の治療の可能性2013
- Author(s)
  中岡良和
- Journal Title
  
  日本循環器学会専門医誌　循環器専門医
  
  Volume: 21 Pages: 271-276
- Data Source
  KAKENHI-PROJECT-23591101
[Journal Article] Interleukin-6 シグナル制御による肺動脈性肺高血圧症の治療の可能性2013
- Author(s)
  中岡良和
- Journal Title
  
  日本循環器学会専門医誌　循環器専門医
  
  Volume: 21 Pages: 271-276
- Data Source
  KAKENHI-PROJECT-25670386
[Journal Article] Interleukin-6 シグナル制御による肺動脈性肺高血圧症の治療の可能性2013
- Author(s)
  中岡良和
- Journal Title
  
  日本循環器学会専門医誌　循環器専門医
  
  Volume: 21 Pages: 271-276
- Data Source
  KAKENHI-PROJECT-25293183
[Journal Article] Tocilizumab for the Treatment of the Patients with Refractory Takayasu Arteritis2013
- Author(s)
  Nakaoka Y, Higuchi K, Arita Y, Otsuki M, Yamamoto K, Hashimoto-Kataoka T, Yasui T, Ikeoka K, Ohtani T, Sakata Y, Shima Y, Kumanogoh A, Yamauchi-Takihara K, Tanaka T, Kishimoto T, Komuro I
- Journal Title
  
  Int Heart J
  
  Volume: 54 Pages: 405-411
- NAID
  130003383361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591101
[Journal Article] 高安動脈炎の治療2013
- Author(s)
  中岡良和、瀧原圭子、小室一成
- Journal Title
  
  日本臨床(増刊号・血管炎)
  
  Volume: 71(Suppl 1) Pages: 173-178
- Data Source
  KAKENHI-PROJECT-23591101
[Journal Article] Gab docking proteins in cardiovascular disease, cancer, and inflammation2013
- Author(s)
  Nakaoka Y.
- Journal Title
  
  International Journal of Inflammation 2012 Article ID 141068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659391
[Journal Article] 高安動脈炎の診断と治療 -生物学的製剤による治療の現状に焦点を当てて2013
- Author(s)
  中岡良和
- Journal Title
  
  医学のあゆみ
  
  Volume: 246 Pages: 5-11
- Data Source
  KAKENHI-PROJECT-25293183
[Journal Article] Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway.2013
- Author(s)
  Rodriguez-Araujo G, Nakagami H, Hayashi H, Mori M, Shiuchi T, Minokoshi Y, Nakaoka Y, Takami Y, Komuro I, Morishita R, Kaneda Y
- Journal Title
  
  Cell Mol Life Sci
  
  Volume: 70 Issue: 6 Pages: 1123-1133
- DOI
  10.1007/s00018-012-1198-8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22126005, KAKENHI-PROJECT-23591101, KAKENHI-PROJECT-24659391, KAKENHI-PROJECT-24790756, KAKENHI-PUBLICLY-23126519
[Journal Article] 影山論文に対するEditorial Comment - 冠動脈・大動脈疾患を合併する巨細胞性動脈炎では厳密な慢性炎症のコントロールに留意する必要がある2013
- Author(s)
  中岡良和
- Journal Title
  
  心臓
  
  Volume: 45 Pages: 1293-1294
- NAID
  130004716912
- Data Source
  KAKENHI-PROJECT-25293183
[Journal Article] Gab docking proteins in cardiovascular disease, cancer, and inflammation2013
- Author(s)
  Nakaoka Y, Komuro I
- Journal Title
  
  Int J Inflam
  
  Volume: 2013 Pages: 141068-141068
- DOI
  10.1155/2013/141068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591101, KAKENHI-PROJECT-24659391
[Journal Article] Tocilizumab for the treatment of patients with refractory takayasu arteritis.2013
- Author(s)
  Nakaoka Y, Higuchi K, Arita Y, Otsuki M, Yamamoto K, Hashimoto-Kataoka T, Yasui T, Ikeoka K, Ohtani T, Sakata Y, Shima Y, Kumanogoh A, Yamauchi-Takihara K, Tanaka T, Kishimoto T, Komuro I.
- Journal Title
  
  Int Heart J.
  
  Volume: 54 Pages: 405-411
- NAID
  130003383361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670386
[Journal Article] Angiopoietin-1 guides directional angiogenesis through integrin αvβ5 signaling for recovery of ischemic retinopathy.2013
- Author(s)
  Lee J, Kim KE, Choi DK, Jang JY, Jung JJ, Kiyonari H, Shioi G, Chang W, Suda T, Mochizuki N, Nakaoka Y, Komuro I, Yoo OJ, Koh GY.
- Journal Title
  
  Sci Transl Med.
  
  Volume: 5 Issue: 203
- DOI
  10.1126/scitranslmed.3006666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591101, KAKENHI-PROJECT-25293183, KAKENHI-PROJECT-25670386
[Journal Article] Endothelial Gab1 Deletion Accelerates Angiotensin II-dependent Vascular Inflammation and Atherosclerosis in Apolipoprotein E Knockout Mice2012
- Author(s)
  Higuchi K, Nakaoka Y, Shioyama W, Arita Y, Hashimoto T, Yasui T, Ikeoka K, Kuroda T, Nishida K, Fujio, Y Yamauchi-Takihara K, Shirai M, Mochizuki N, Komuro I.
- Journal Title
  
  Circulatino Journal
  
  Volume: in press
- NAID
  10030505176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591101
[Journal Article] 血管体性幹細胞2012
- Author(s)
  中岡良和
- Journal Title
  
  BioClinica
  
  Volume: 27 Pages: 844-848
- Data Source
  KAKENHI-PROJECT-24659391
[Journal Article] 高安動脈炎の治療2012
- Author(s)
  中岡良和
- Journal Title
  
  日本臨床(増刊号血管炎)
  
  Volume: 71 Supple 1 Pages: 173-178
- Data Source
  KAKENHI-PROJECT-24659391
[Journal Article] Endothelial Gab1 deletion accelerates angiotensin II-dependent vascular inflammation and atherosclerosis in apolipoprotein E knockout mice2012
- Author(s)
  Higuchi, K., Nakaoka, Y., Shioyama, W., Arita, Y., Hashimoto, T., Yasui, T., Ikeoka, K., Kuroda, T., Minami, T., Nishida, K., Fujio, Y., Yamauchi-Takihara, K., Shirai, M., Mochizuki, N., Komuro, I
- Journal Title
  
  Circ. J
  
  Volume: 76 Pages: 2031-2040
- NAID
  10030505176
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Endothelial Gab1 Deletion Accelerates Angiotensin II-Dependent Vascular Inflammation and Atherosclerosis in Apolipoprotein E Knockout Mice2012
- Author(s)
  Higuchi K
- Journal Title
  
  Circ J
  
  Volume: 76 Issue: 8 Pages: 2031-2040
- DOI
  10.1253/circj.CJ-11-1507
- NAID
  10030505176
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590576, KAKENHI-PROJECT-23591101, KAKENHI-PROJECT-24659391
[Journal Article] 高安動脈炎の治療2012
- Author(s)
  中岡良和
- Journal Title
  
  日本臨床　（増刊号　血管炎）
  
  Volume: 71 Supple 1 Pages: 173-178
- Data Source
  KAKENHI-PROJECT-24659391
[Journal Article] トラスツズマブの心毒性から明らかにされたNeuregulin-1/ErbBシグナルの重要性2012
- Author(s)
  中岡良和
- Journal Title
  
  心臓
  
  Volume: 44 Pages: 698-699
- Data Source
  KAKENHI-PROJECT-24659391
[Journal Article] Sildenafil and steroid thera py effectively improved POEMS syndrom e-associated pulmonary arterial hypertensi on2011
- Author(s)
  Shimomura Y, Hara M, Mizote I, Nakaoka Y, Tanaka H, Asano Y, Sakata Y, Komuro I
- Journal Title
  
  International Journal of Hematology
  
  Volume: 92 Pages: 774-776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] Gab1 is essential for postnatal angiogenesis via hepatocyte growth factor/c-Met signaling2011
- Author(s)
  Shioyama W, Nakaoka Y, Higuchi K, Minami T, Taniyama Y, Nishida K, Kidoya H, Sonobe T, Naito H, Arita Y, Hashimoto T, Kuroda T, Fujio Y, Shirai M, Takakura N, Morishita R, Yamauchi-Takihara K, Kodama T, Hirano T, Mochizuki N, Komuro I
- Journal Title
  
  Circ Res
  
  Volume: 108 Issue: 6 Pages: 664-675
- DOI
  10.1161/circresaha.110.232223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591101, KAKENHI-PROJECT-23650213
[Journal Article] 冠動脈疾患研究の・治療の進歩と今後の課題2011
- Author(s)
  中岡良和、小室一成
- Journal Title
  
  日本臨床
  
  Volume: 69(Suppl 7) Pages: 20-24
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] Docking protein Gab1 is an essential component of postnatal angiogenesis after ischemia via HGF/c-Met signaling2011
- Author(s)
  Shioyama, W., Nakaoka, Y., Higuchi, K., Minami, T., Taniyama, Y., Nishida, K., Kidoya, H., Naito, H., Arita, Y., Hashimoto, T., Sanada, F., Fujio, Y., Shirai, M., Takakura, N., Morishita, R., Yamauchi-Takihara, K., Kodama, T., Hirano, T., Mochizuki, N., Komuro, I
- Journal Title
  
  Circ. Res
  
  Volume: 108 Pages: 664-675
- Data Source
  KAKENHI-PROJECT-23390057
[Journal Article] Gab1 is essential for postnatal angiogenesis via hepatocyte growth factor/c-Met signaling.2011
- Author(s)
  Shioyama W, Nakaoka Y, Higuchi K, Minami T, Taniyama Y, Nishida K, Kidoya H, Sonobe T, Naito H, Arita Y, Hashimoto T, Kuroda T, Fujio Y, Shirai M, Takakura N, Morishita R, Yamauchi-Takihara K, Kodama T, Hirano T, Mochizuki N, Komuro I (co-corresponding author)
- Journal Title
  
  Circulation Research
  
  Volume: 108(Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] 冠動脈疾患研究・治療の進歩と今後の課題2011
- Author(s)
  中岡良和、小室一成
- Journal Title
  
  日本臨床
  
  Volume: 69(Suppl 7) Pages: 20-24
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] Gab1 is essential for postnatal a ngiogenesis via hepatocyte growth factor/ c-Met signaling2011
- Author(s)
  Shioyama W, Nakaoka Y
- Journal Title
  
  Circ Res
  
  Volume: 108 Pages: 664-675
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] A case of non-cardiogenic acute pulmonary edem a in a patient with POEMS syndrome-ass ociated pulmonary arterial hypertension2011
- Author(s)
  Hara M, Mizote I, Nakaoka Y, Tanaka H, Asano Y, Sakata Y, Komuro I
- Journal Title
  
  A nn Hematol
  
  Volume: 90 Pages: 489-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] Pulmonary arterial hypertension associated with chronic active Epstein-Barr virus infection.2011
- Author(s)
  Hashimoto T, Sakata Y, Fukushima K, Maeda T, Arita Y, Shioyama W, Nakaoka Y, Hori Y, Morii E, Aozasa K, Kanakura Y, Yamauchi-Takihara K, Komuro I.
- Journal Title
  
  Internal Medicine
  
  Volume: 50 Pages: 119-24
- NAID
  130000413209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] 冠動脈疾患研究の・治療の進歩と今後の課題2011
- Author(s)
  中岡良和、小室一成
- Journal Title
  
  日本臨床
  
  Volume: 69(Suppl 7) Pages: 20-24
- Data Source
  KAKENHI-PROJECT-23591101
[Journal Article] SHP2 mediates gp130-dependent cardiomyocyte hypertrophy via negative regulation of skeletal alpha-actin gene.2010
- Author(s)
  Nakaoka Y, Shioyama W, Kunimoto S, Arita Y, Higuchi K, Yamamoto K, Fujio Y, Nishida K, Kuroda T, Hirota H, Yamauchi-Takihara K, Hirano T, Komuro I, Mochizuki N.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 49 Pages: 157-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] Angiopoietin-1の心血管系での役割2010
- Author(s)
  中岡良和
- Journal Title
  
  循環器内科
  
  Volume: 67(2) Pages: 178-184
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] Yamauchi-Takihara K. The efficacy of tocilizumab i n a patient with pulmonary arterial hyper tension associated with Castleman' s diseas e2010
- Author(s)
  Arita Y, Sakata Y, Sudo T, Maeda T, Ma tsuoka K, Tamai K, Higuchi K, Shioyam a W, Nakaoka Y, Kanakura Y
- Journal Title
  
  Heart Vessels
  
  Volume: 25 Pages: 444-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] A case of non-cardiogenic acute pulmonary edema in a patient with POEMS syndrome-associated pulmonary arterial hypertension2010
- Author(s)
  Hara M, Mizote I, Nakaoka Y, Tanaka H, Asano Y, Sakata Y, Komuro I
- Journal Title
  
  Annals of Hematology
  
  Volume: 90(Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] Therapeutic activation of Signal Transducer and Activator of Transcription 3 by Interleukin-11 Ameriolates Cardiac Fibrosis After Myocardial Infarction2010
- Author(s)
  Obana M, Maeda M, Takeda K, Hayama A, Mohri T, Yamashita T, Nakaoka Y, Takeda K, Matsumiya G, Azuma J, Fujio Y
- Journal Title
  
  Circulation 121
  
  Pages: 684-391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] SHP2 mediates gp130-dependent cardiomyocyte hypertrophy via negative regulation of skeletalα-actin gene2010
- Author(s)
  Nakaoka Y
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 49 Pages: 157-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] Sildenafil and steroid therapy effectively improved POEMS syndrome-associated pulmonary arterial hypertension.2010
- Author(s)
  Shimomura Y, Hara M, Mizote I, Nakaoka Y, Tanaka H, Asano Y, Sakata Y, Komuro I.
- Journal Title
  
  International Journal of Hematology
  
  Volume: 92 Pages: 774-6
- NAID
  10027674619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] SHP2 mediates gp130-dependent cardiomyocyte hypertrophy via negative regulation of skeletal alpha-actin gene2010
- Author(s)
  Nakaoka Y, Shioyama W, Arita Y, Higuchi K, Kunimoto S, Fujio Y, Nishida K, Kuroda T, Hirota H, Yamauchi-Takihara K, Komuro I, Mochizuki N.
- Journal Title
  
  Journal of Molecular and Cellular Cardiology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] Therapeutic activation of STAT3 by I nterleukin-11 ameliorates cardiac fibrosis after myocardial infaraction2010
- Author(s)
  Obana M, Maeda M, Takeda K, Hayama A, Mohri T, Yamashita T, Nakaoka Y, Takeda K, Matsumiya G, Azuma J, Fujio Y
- Journal Title
  
  Circulation
  
  Volume: 121 Pages: 684-691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] Angiopoietin-1の心血管系での役割2010
- Author(s)
  中岡良和
- Journal Title
  
  循環器内科 (in press)
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] 心腎連関と内皮機能2010
- Author(s)
  中岡良和、小室一成
- Journal Title
  
  腎と透析
  
  Volume: 69(4) Pages: 422-426
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] 心血管調節因子 : Neuregulin-1と Angiopoietin-1が形成する心臓パラクラインシグナルネットワーク2009
- Author(s)
  中岡良和
- Journal Title
  
  心臓 41
  
  Pages: 1298-1301
- NAID
  130003376832
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] A role for Gab1/SHP2 in thrombin activation of PAK1 : gene transfer of kinase-dead PAK1 inhibits injury-induced restenosis2009
- Author(s)
  Wang D, Paria BC, Zhang Q, Karpurapu M, Li Q, Gerthoffer WT, Nakaoka Y, Rao GN.
- Journal Title
  
  Circulation Research 104
  
  Pages: 1066-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] Clinical sig nificance of plasma endothelin-1 level aft er bosentan administration in pulmonary arterial hypertension2009
- Author(s)
  Hiramoto Y, Shioyama W, Higuchi K, Ar ita Y, Kuroda T, Sakata Y, Nakaoka Y, Fujio Y, Yamauchi-Takihara K
- Journal Title
  
  J Cardiol
  
  Volume: 53 Pages: 374-80
- NAID
  10025183776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] 心血管調節因子: Neuregul in-1とAngiopoietin-1が形成するパラクラインシグナルネットワーク2009
- Author(s)
  中岡良和
- Journal Title
  
  心血管調節因子: Neuregul in-1とAngiopoietin-1が形成するパラクラインシグナルネットワーク
  
  Volume: 41 Pages: 1298-1301
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] R ao GN. A role for Gab1/ SHP2 in thromb in activation of PAK1 : gene transfer of k inase-dead PAK1 inhibits injury-induced r estenosis2009
- Author(s)
  Wang D, Paria BC, Zhang Q, Karpurapu M, Li Q, Gerthoffer WT, Nakaoka Y
- Journal Title
  
  Circ Res
  
  Volume: 104 Pages: 1066-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590930
[Journal Article] Interaction of Scaffolding Adaptor Protein Gab1 with Tyrosine Phosphatase SHP2 Negatively Regulates IGF-I-dependent Myogenic Differentiation via the ERK1/2 Signaling Pathway2008
- Author(s)
  Koyama T. ^*, Nakaoka Y. ^*#, et al. (^*equal contribution; #corresponding author)
- Journal Title
  
  Journal of Biological Chemistry 283
  
  Pages: 24234-24244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590844
[Journal Article] サイトカインシグナルによる心不全の制御機構2008
- Author(s)
  瀧原圭子、中岡良和
- Journal Title
  
  心臓 40
  
  Pages: 181-186
- Data Source
  KAKENHI-PROJECT-19590844
[Journal Article] Interaction of Scaffolding Adaptor Protein Gab1 with Tyrosine Phosphatase SHP2 Negatively Regulates IGF-I-dependent Myogenic Differentiation via the ERK1/2 Signaling Pathway2008
- Author(s)
  Koyama T¶, Nakaoka Y¶*, Fujio Y, Hirota H, Nishida K, Sugiyama S, Okamoto K, Yamauchi-Takihara K, Yoshimura M, Mochizuki S, Hori M, Hirano T, Mochizuki N.
- Journal Title
  
  J. Biol. Chem(*corresponding author, ¶co-firstauthor) 283
  
  Pages: 24234-24244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590844
[Journal Article] Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling2007
- Author(s)
  Nakaoka Y., et. al.
- Journal Title
  
  Journal of Clinical Investigation 117
  
  Pages: 1771-1781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590844
[Journal Article] Gab family proteins are essential for postnatal maintenance of cardiac function through transmitting neuregulin-1/ErbB signaling2007
- Author(s)
  Nakaoka Y*, Nishida K, Narimatsu M, Kamiya A, Minami T, Sawa H, Okawa K, Fujio Y, Koyama T, Maeda M, Sone M, Yamasaki S, Arai Y, Koh GY, Kodama T, Hirota H, Otsu K, Hirano T, and Mochizuki N*.
- Journal Title
  
  J. Clin. Invest(*co-correspondingauthor) 117
  
  Pages: 1771-1781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590844
[Patent] 肺高血圧症治療薬およびそのスクリーニング法2014
- Inventor(s)
  中岡良和、片岡崇弘
- Industrial Property Rights Holder
  中岡良和、片岡崇弘
- Industrial Property Rights Type
  特許
- Filing Date
  2014-09-08
- Data Source
  KAKENHI-PROJECT-25293183
[Patent] 肺高血圧治療薬およびそのスクリーニング法2014
- Inventor(s)
  中岡良和、片岡崇弘
- Industrial Property Rights Holder
  中岡良和、片岡崇弘
- Industrial Property Rights Type
  特許
- Filing Date
  2014-09-08
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] Gut Dysbiosis with Oral-derived Bacteria Campylobacter as a Potential Predictor for Aortic Aneurysm Formation and Progression in Takayasu Arteritis.2024
- Author(s)
  Yoshikazu Nakaoka
- Organizer
  第88回日本循環器学会学術集会（Plenary symposium）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27605
[Presentation] 高安動脈炎の薬物治療の最新情報2023
- Author(s)
  中岡　良和
- Organizer
  第31回日本心血管インターベンション治療学会学術集会(CVIT2023)
- Invited
- Data Source
  KAKENHI-PROJECT-23K27605
[Presentation] 高安動脈炎の診断と治療の最新情報（教育講演）2023
- Author(s)
  中岡　良和
- Organizer
  第51回日本血管外科学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27605
[Presentation] Evaluation of the disease activity and therapeutic management of Takayasu arteritis2023
- Author(s)
  Yoshikazu Nakaoka
- Organizer
  第67回日本リウマチ学会総会・学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27605
[Presentation] 腸内細菌叢の変容と心血管病との関連性（教育講演）2023
- Author(s)
  中岡　良和
- Organizer
  第71回日本心臓病学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27605
[Presentation] 肺高血圧症におけるIL-6の重要性：遺伝子改変ラットを用いた検討2021
- Author(s)
  稲垣薫克、石橋知彦、岡澤慎、正木豪、真鍋侑資、浅野遼太郎、大郷剛、中岡良和
- Organizer
  第29回日本血管生物医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08506
[Presentation] Anti-interleukin-21 aptamer treatment improves pathology in a rodent models of pulmonary hypertension.2021
- Author(s)
  Tadakatsu Inagaki, Ryotaro Asano, Marie Mitsui, Tomohiko Ishibashi, Makoto Okazawa, Takeshi Ogo, Yoshikazu Nakaoka
- Organizer
  The 5th JCS Council Forum on Basic Cardio Vascular Research
- Data Source
  KAKENHI-PROJECT-19K08506
[Presentation] Interleukin-21阻害による肺動脈性肺高血圧症の新規治療法開発2020
- Author(s)
  稲垣薫克,浅野遼太郎,石橋知彦,岡澤慎,正木豪,三井麻利江,青木一晃,大郷剛,中岡良和
- Organizer
  第5回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08506
[Presentation] Critical Roles of Interleukin-21 Signaling in the Pathogenesis of Pulmonary Arterial Hypertension2020
- Author(s)
  Tadakatsu Inagaki, Tomohiko Ishibashi, Makoto Okazawa, Takeshi Masaki, Marie Mitsui, Kazuteru Aoki, Ryotaro Asano, Takeshi Ogo, Yoshikazu Nakaoka
- Organizer
  The 21st International Vascular Biology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08506
[Presentation] gp130 Signaling in CD4 Cells Is Important for the Pathogenesis of Pulmonary Arterial Hypertension2020
- Author(s)
  Tomohiko Ishibashi, Takeshi Masaki, Tadakatsu Inagaki, Makoto Okazawa, Yoshikazu Nakaoka
- Organizer
  The 21st International Vascular Biology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08506
[Presentation] CD4陽性細胞におけるgp130シグナルは肺高血圧症の病態形成に重要である2019
- Author(s)
  石橋知彦、正木豪、稲垣薫克、森啓悦、浅野遼太郎、岡澤慎、中岡良和
- Organizer
  第27回日本血管生物医学会
- Data Source
  KAKENHI-PROJECT-19K08506
[Presentation] 炎症性サイトカインシグナル阻害によるPAHの新規治療法開発2019
- Author(s)
  稲垣薫克、大郷剛、中岡良和
- Organizer
  第4回日本肺高血圧・肺循環学会
- Data Source
  KAKENHI-PROJECT-19K08506
[Presentation] 大型血管炎（高安動脈炎・巨細胞性動脈炎）に対する生物学的製剤治療の新展開2019
- Author(s)
  中岡良和
- Organizer
  第49回日本心臓血管外科学会学術総会（岡山）特別企画04「大型血管炎治療の最前線」
- Invited
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] 炎症性サイトカインの肺高血圧症病態での役割.2019
- Author(s)
  中岡良和
- Organizer
  第92回日本薬理学会（大阪）シンポジウム23．
- Invited
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] Novel Treatment Strategy for Large Vessel Vasculitis Using Anti-Interleukin-6 Receptor Antibody.2019
- Author(s)
  Nakaoka Y.
- Organizer
  第83回日本循環器学会（横浜）シンポジウム3．Diagnosis and Management of Large Vessel Vasculitis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] Novel Treatment for Large Vessel Vasculitis Targeting Inflammatory Cytokine Signaling.2018
- Author(s)
  中岡良和
- Organizer
  第82回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] Interleukin-6 Blockade Therapy for Pulmonary Arterial Hypertension and Large Vessel Vasculitis.2018
- Author(s)
  Nakaoka Y.
- Organizer
  第2回日本循環器学会基礎研究フォーラム（奈良）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] Interleukin-6/Interleukin-21 Signaling Axis in the Pathogenesis of Pulmonary Arterial Hypertension.2018
- Author(s)
  中岡良和2018年10月11日
- Organizer
  第22回日本心不全学会（東京）シンポジウム6（PAH）
- Invited
- Data Source
  KAKENHI-PROJECT-16H05126
[Presentation] 大型血管炎に対する生物学的製剤治療.2018
- Author(s)
  中岡良和
- Organizer
  第62回日本リウマチ学会総会・学術集会　特別シンポジウム４
- Invited
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] Interleukin-6/Interleukin-21 Signaling Axis in the Pathogenesis of Pulmonary Arterial Hypertension.2018
- Author(s)
  中岡良和
- Organizer
  第22回日本心不全学会（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] 肺高血圧も来す高安動脈炎Up to date.2018
- Author(s)
  中岡良和
- Organizer
  第３回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] 大型血管炎の診療ガイドライン2017
- Author(s)
  中岡良和
- Organizer
  第61回日本リウマチ学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] Update on Large Vessel Vasculitis～Pathogenesis, Diagnosis and Treatment～2017
- Author(s)
  Yoshikazu Nakaoka
- Organizer
  The 18th International Vasculitis and ANCA Workshop (Vasculitis 2017)
- Place of Presentation
  東京大学伊藤国際ホール(メインホール）
- Year and Date
  2017-03-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] 炎症性シグナルによる肺高血圧症の病態形成機構2017
- Author(s)
  中岡良和
- Organizer
  第2回日本肺高血圧・肺循環学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] Inflammatory Cytokines in the Pathogenesis of Pulmonary Arterial Hypertension2017
- Author(s)
  Nakaoka Y.
- Organizer
  The 15th Japan-Korea Joint Symposium on Vascular Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] ステロイド治療抵抗性大型血管炎の治療2017
- Author(s)
  中岡良和
- Organizer
  第32回日本臨床リウマチ学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] 高安動脈炎と巨細胞性動脈炎の病態と治療2017
- Author(s)
  中岡良和
- Organizer
  第22回日本血管病理研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] 炎症性サイトカインのInterleukin-6を標的としたPAH治療の可能性2017
- Author(s)
  中岡良和、大郷剛.
- Organizer
  第2回日本肺高血圧・肺循環学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] Long-Term Efficacy and Safety of Tocilizumab in Patients with Refractory Takayasu Arteritis Treated Continuously Over 52 Weeks: Results from Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial and Open-Label Extension in Japan.2017
- Author(s)
  Nakaoka Y, Isobe M, Takei S, Tanaka Y, Ishii T, Yokota S, Nishimoto N.
- Organizer
  American College of Rheumatology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] Ｃｒｉｔｉｃａｌ　ｒｏｌｅｓ　ｏｆ　ｉｎｔｅｒｌｅｕｋｉｎ－６／ｉｎｔｅｒｌｅｕｋｉｎ－２１－ｓｉｇｎａｌｉｎｇ　ａｘｉｓ　ｉｎ　ｔｈｅ　ｐａｔｈｏｇｅｎｅｓｉｓ　ｏｆ　ｐｕｌｍｏｎａｒｙ　ａｒｔｅｒｉａｌ　ｈｙｐｅｒｔｅｎｓｉｏｎ．2016
- Author(s)
  中岡良和
- Organizer
  第39回日本分子生物学会年会シンポジウム
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] 2016 Oral presentation;Efficacy and Safety of Tocilizumab in patients with refractory Takayasu Arteritis:Results from randomized double-blind placebo-controlled trial in Japan.2016
- Author(s)
  Nakaoka Y.
- Organizer
  American College of Rheumatology (ACR)
- Place of Presentation
  ワシントンDC　（米国）
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] 炎症性サイトカインによる肺高血圧症の病態形成機構2016
- Author(s)
  中岡良和
- Organizer
  第2回Ｊ－ＩＳＰ（日本薬物療法学会）学術集会
- Place of Presentation
  阿波観光ホテル
- Year and Date
  2016-06-26
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] A novel cardiomyocyte-specific isoform of docking protein Gab1 plays a critical role in neuregulin-1/ErbB signaling2016
- Author(s)
  安居琢,,山本かおり,有田陽,片岡崇弘,正木豪,小室一成,坂田泰史,中岡良和
- Organizer
  日本循環器学会
- Place of Presentation
  "せんだい青葉山交流広場　特設会場
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] 炎症性シグナルに焦点を当てた肺高血圧の病態形成機構.2016
- Author(s)
  中岡良和
- Organizer
  第1回日本肺高血圧・肺循環器学会総会・学術集会シンポジウム
- Place of Presentation
  京王プラザホテル
- Year and Date
  2016-10-02
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] 大型血管炎の診療ガイドライン2016
- Author(s)
  中岡良和
- Organizer
  第60回日本リウマチ学会総会・学術集会シンポジウム
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-04-21
- Invited
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] Ｉｎｔｅｒｌｅｕｋｉｎ－６／ｉｎｔｅｒｌｅｕｋｉｎ－２１－ｓｉｇｎａｌｉｎｇａｘｉｓ　ｐｌａｙｓ　ａ　ｃｒｉｔｉｃａｌ　ｒｏｌｅ　ｉｎ　ｔｈｅ　pathogenesis of pulmonary arterial hypertension.2016
- Author(s)
  中岡良和
- Organizer
  第24回日本血管生物医学会総会シンポジウム
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2016-12-10
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] 炎症性サイトカインによる肺高血圧症の病態形成機構2016
- Author(s)
  中岡良和
- Organizer
  第2回Ｊ－ＩＳＣＰ(日本薬物療法学会）学術集会.
- Place of Presentation
  阿波観光ホテル
- Year and Date
  2016-06-26
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] A novel cardiomyocyte-specific isoform of docking protein Gab1 plays a critical role in neuregulin-1/ErbB signaling2016
- Author(s)
  安居琢,,山本かおり,有田陽,片岡崇弘,正木豪,小室一成,坂田泰史,中岡良和
- Organizer
  日本循環器学会
- Place of Presentation
  "せんだい青葉山交流広場　特設会場
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] 2016 Oral presentation;Efficacy and Safety of Tocilizumab in patients with refractory Takayasu Arteritis:Results from randomized double-blind placebo-controlled trial in Japan.2016
- Author(s)
  Nakaoka Y
- Organizer
  American College of Rheumatology (ACR)
- Place of Presentation
  ワシントンＤＣ
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] Ｃｒｉｔｉｃａｌ　ｒｏｌｅｓ　ｏｆ　ｉｎｔｅｒｌｅｕｋｉｎ－６／ｉｎｔｅｒｌｅｕｋｉｎ－２１－ｓｉｇｎａｌｉｎｇ　ａｘｉｓ　ｉｎ　ｔｈｅ　ｐａｔｈｏｇｅｎｅｓｉｓ　ｏｆ　ｐｕｌｍｏｎａｒｙ　ａｒｔｅｒｉａｌ　ｈｙｐｅｒｔｅｎｓｉｏｎ．2016
- Author(s)
  中岡　良和
- Organizer
  第39回日本分子生物学会年会シンポジウム
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] Ｉｎｔｅｒｌｅｕｋｉｎ－６／ｉｎｔｅｒｌｅｕｋｉｎ－２１－ｓｉｇｎａｌｉｎｇａｘｉｓ　ｐｌａｙｓ　ａ　ｃｒｉｔｉｃａｌ　ｒｏｌｅ　ｉｎ　ｔｈｅ　pathogenesis of pulmonary arterial hypertension.2016
- Author(s)
  中岡良和
- Organizer
  第24回日本血管生物医学会総会シンポジウム
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2016-12-10
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] 炎症性シグナルに焦点を当てた肺高血圧の病態形成機構2016
- Author(s)
  中岡良和
- Organizer
  第1回日本肺高血圧・肺循環器学会総会・学術集会シンポジウム
- Place of Presentation
  京王プラザホテル
- Year and Date
  2016-10-02
- Invited
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] 大型血管炎の診療ガイドライン2016
- Author(s)
  中岡良和
- Organizer
  第60回リウマチ学会総会・学術集会シンポジｙム
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-04-21
- Invited
- Data Source
  KAKENHI-PROJECT-16H05298
[Presentation] A novel cardiomyocyte-specific isoform of docking protein Gab1 plays a critical role in neuregulin-1/ErbB signaling2015
- Author(s)
  安居琢,山本かおり,有田陽,片岡崇弘,正木豪,小室一成,坂田泰史,中岡良和
- Organizer
  MCCⅡ
- Place of Presentation
  ヒルトン福岡シーホーク
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] 難治性高安動脈炎に対する抗interleukin-6受容体抗体トシリズマブによる治療の試み2015
- Author(s)
  正木　豪,中岡良和,有田陽,片岡崇弘,安居琢,大谷朋仁,瀧原圭子,坂田泰史
- Organizer
  第一回J-JSCP学術集会　国際心血管薬物療法学会日本部会
- Place of Presentation
  ハイアットリージェンシー京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] A novel cardiomyocyte-specific isoform of docking protein Gab1 plays a critical role in neuregulin-1/ErbB signaling2015
- Author(s)
  安居琢,有田陽,瀧原圭子,小室一成,坂田泰史,中岡良和
- Organizer
  ISHR日本部会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] The Role of Angiopoietin-1 in Coronary Venogenesis in the Developing Heart2015
- Author(s)
  中岡良和
- Organizer
  日本循環器学会　会長特別企画シンポ・心臓の発生と再生
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] The Role of Angiopoietin-1 in Coronary Venogenesis in the Developing Heart2015
- Author(s)
  中岡良和
- Organizer
  日本循環器学会　会長特別企画シンポ・心臓の発生と再生
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] Angiopoietin-1 derived from myocardium is essential for coronary vein formation in the developing heart2015
- Author(s)
  中岡良和
- Organizer
  日本血管生物医学会春季特別シンポジウム
- Place of Presentation
  大阪大学微生物病研究所谷口記念講堂
- Year and Date
  2015-05-13
- Invited
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] 炎症制御で血管病を治療する2015
- Author(s)
  中岡良和
- Organizer
  日本NO学会アフタヌーンセミナー
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2015-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] 炎症制御で血管病を治療する2015
- Author(s)
  中岡良和
- Organizer
  日本NO学会アフタヌーンセミナー
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2015-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] A novel cardiomyocyte-specific isoform of docking protein Gab1 plays a critical role in neuregulin-1/ErbB signaling2015
- Author(s)
  安居琢,有田陽,瀧原圭子,小室一成,坂田泰史,中岡良和
- Organizer
  ISHR日本部会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] Interleukin-6/interleukin-21 signaling axis in the pathogenesis of pulmonary arterial hypertension2015
- Author(s)
  中岡良和
- Organizer
  第21回日本遺伝子治療学会学術集会（血管生物医学会合同シンポジウム・血管生物学のフロンティア）
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-07-25
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] 難治性高安動脈炎に対する抗interleukin-6受容体抗体トシリズマブによる治療の試み2015
- Author(s)
  正木豪,中岡良和,有田陽,片岡崇弘,安居琢,大谷朋仁,瀧原圭子,坂田泰史
- Organizer
  第１回Ｊ－ＩＳＣＰ学術集会　国際心血管薬物療法学会日本部会
- Place of Presentation
  ハイアットリージェンシー京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] Angiopoietin-1 derived from myocardium is essential for coronary vein formation in the developing heart2015
- Author(s)
  中岡良和
- Organizer
  日本血管生物医学会春季特別シンポジウム
- Place of Presentation
  大阪大学微生物病研究所谷口記念講堂
- Year and Date
  2015-05-13
- Invited
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] A novel cardiomyocyte-specific isoform of docking protein Gab1 plays a critical role in neuregulin-1/ErbB signaling2015
- Author(s)
  安居琢,山本かおり,有田陽,片岡崇弘,正木豪,小室一成,坂田泰史,中岡良和
- Organizer
  MCCⅡ
- Place of Presentation
  ヒルトン福岡シーホーク
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] Interleukin-6/interleukin-21 signaling axis in the pathogenesis of pulmonary arterial hypertension2015
- Author(s)
  中岡良和
- Organizer
  第21回日本遺伝子治療学会学術集会（血管生物医学会合同シンポジウム・血管生物学のフロンティア）
- Place of Presentation
  大阪国際会議場
- Year and Date
  2015-07-25
- Data Source
  KAKENHI-PROJECT-15K15309
[Presentation] 難治性高安動脈炎に対するトシリズマブの安全性と有効性の検討2014
- Author(s)
  中岡良和
- Organizer
  第111回　日本内科学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2014-04-09
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] The role of angiopoietin-1 in coronary vessel formation in the developing heart2014
- Author(s)
  Yoshikazu Nakaoka
- Organizer
  第18回国際血管生物学会（IVBM2014)
- Place of Presentation
  京都みやこめっせ
- Year and Date
  2014-04-14
- Invited
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] The role of angiopoietin-1 in coronary vessel formation in the developing heart2014
- Author(s)
  Yoshikazu Nakaoka
- Organizer
  第18回国際血管生物学会（ＩＶＢＭ2014）
- Place of Presentation
  京都みやこめっせ
- Year and Date
  2014-04-14
- Invited
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] 難治性高安動脈炎に対するトシリズマブによるinterleukin-6阻害療法による治療の試み2014
- Author(s)
  中岡良和
- Organizer
  日本心臓病学会
- Place of Presentation
  仙台国際センター
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] 難治性高安動脈炎に対するトシリズマブの安全性と有効性の検討2014
- Author(s)
  中岡良和
- Organizer
  第111回　日本内科学会総会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2014-04-09
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] 難治性高安動脈炎に対するトシリズマブによるinterleukin-6阻害療法による治療の試み2014
- Author(s)
  中岡良和
- Organizer
  日本心臓病学会
- Place of Presentation
  仙台国際センター
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] Tocilizumab Ameliorates Vascular Inflammation and Clinical Symptoms in the Patients with Takayasu Arteritis Refractory to Glucocorticoids2013
- Author(s)
  Nakaoka Y
- Organizer
  American College of Cardiology (ACC) 2013
- Place of Presentation
  米国カリフォルニア州サンフランシスコ
- Data Source
  KAKENHI-PROJECT-24659391
[Presentation] Angiopoietin-1 secreted from myocardium is essential for the formation of coronary veins in the developing heart2013
- Author(s)
  Arita Y, Nakaoka Y, Matsunaga T, Kidoya H, Yamamizu K, Arima Y, Higuchi K, Hashimoto T, Ikeoka K, Yasui T, Nishiyama K, Kurihara H, Yamauchi-Takihara K, Yamagishi H, Takakura N, Mochizuki N, Koh GY, Komuro I
- Organizer
  第30回国際心臓研究学会(ISHR)日本部会総会
- Place of Presentation
  La Valencia Hotel(アメリカ合衆国・サンディエゴ)
- Year and Date
  2013-06-29
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] アンギオポイエチン1は静脈洞の未分化血管内皮細胞を遊走・分化させ冠静脈形成に必須の因子である2013
- Author(s)
  有田陽、中岡良和、松永太一、木戸屋浩康、橋本崇弘、池岡邦泰、高倉伸幸、望月直樹、山下潤、小室一成
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  千里阪急ホテル(大阪府豊中市)
- Year and Date
  2013-09-27
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] 低酸素誘発性肺高血圧モデルでIL-6/Th17細胞シグナルは肺血管リモデリングに必須である2013
- Author(s)
  片岡　崇弘、中岡良和、曽野部崇、保仙　直毅、稲垣　薫克、樋口香織、有田陽、安居琢、池岡邦泰、正木　豪、瀧原圭子、白井幹康、小室一成
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  千里阪急ホテル(大阪府豊中市)
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] Blockade of Interleukin-6 (IL-6) signaling by Anti-IL-6 Receptor Monoclonal Antibody might be a Promising Therapeutic Strategy for Pulmonary Arterial Hypertension2013
- Author(s)
  Nakaoka Y
- Organizer
  第77回日本循環器学会
- Place of Presentation
  横浜、パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24659391
[Presentation] Blockade of interleukin-6 signaling prevents hypoxia induced pulmonary hypertension in mice2013
- Author(s)
  Takahiro Hashimoto-Kataoka, Yoshikazu Nakaoka, Takashi Sonobe, Kaori Higuchi, Yoh Arita, Taku Yasui, Kuniyasu Ikeoka, Takeshi Masaki, Keiko Yamauchi-Takihara, Mikiyasu Shirai, Issei Komuro
- Organizer
  American Heart Association Scientific Sessions 2013
- Place of Presentation
  Dallas Convention Center (Dallas, TX, USA)
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] Blockade of interleukin-6(IL-6) Signaling by Anti-IL-6 Monoclonal Antibody might be a Promising Therapeutic Strategy for Pulmonary Arterial Hypertension2013
- Author(s)
  Nakaoka Y
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2013-03-16
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] Blockade of interleukin-6 signaling prevents hypoxia induced pulmonary hypertension in mice2013
- Author(s)
  Hashimoto-Kataoka T, Nakaoka Y, Sonobe T, Higuchi K, Arita Y, Yasui T, Ikeoka K, Masaki T, Yamauchi-Takihara K, Shirai M, Komuro I
- Organizer
  American Heart Association Scientific Sessions 2013
- Place of Presentation
  Dallas Convention Center (アメリカ合衆国・ダラス)
- Year and Date
  2013-11-17
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] 血管平滑筋細胞由来のアンジオポエチン1は下肢虚血血管新生時の動脈化に重要である2013
- Author(s)
  池岡邦泰、中岡良和、曽野部崇、白井幹康、樋口香織、有田陽、片岡崇弘、安居琢、正木豪、瀧原圭子、小室一成
- Organizer
  第4回Molecular Cardiovascular ConferenceII
- Place of Presentation
  キロロリゾートホテルピアノ(北海道余市郡赤井川村)
- Year and Date
  2013-09-06
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] Blockade of Interleukin-6 (IL-6) signaling by Anti-IL-6 Receptor Monoclonal Antibody might be aPromising Therapeutic Strategy for Pulmonary Arterial Hypertension2013
- Author(s)
  Nakaoka Y
- Organizer
  第77回日本循環器学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24659391
[Presentation] 低酸素誘発性肺高血圧モデルでIL-6/Th17細胞シグナルは肺血管リモデリングに必須である2013
- Author(s)
  片岡崇弘、中岡良和、曽野部崇、保仙直毅、稲垣薫克、樋口香織、有田陽、安居琢、池岡邦泰、正木豪、瀧原圭子、白井幹康、小室一成
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  千里阪急ホテル(大阪府豊中市)
- Year and Date
  2013-09-27
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] 血管平滑筋細胞由来のアンジオポエチン1は下肢虚血血管新生時の動脈化に重要である2013
- Author(s)
  池岡邦泰、中岡良和、曽野部崇、白井幹康、樋口香織、有田陽、片岡崇弘、安居琢、正木豪、瀧原圭子、小室一成
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  千里阪急ホテル(大阪府豊中市)
- Year and Date
  2013-09-27
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] 血管形成研究の最前線「冠静脈形成の分子機構」2013
- Author(s)
  中岡良和、有田陽、松永太一、山下潤、小室一成
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  千里阪急ホテル(大阪府豊中市)
- Year and Date
  2013-09-26
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] Tocilizumab Ameliorates Vascular Inflammation and Clinical Symptoms in the Patients with TakayasuArteritis Refractory to Glucocorticoids2013
- Author(s)
  Nakaoka Y
- Organizer
  American College of Cardiology (ACC) 2013
- Place of Presentation
  米国カリフォルニア州サンフランシスコ
- Data Source
  KAKENHI-PROJECT-24659391
[Presentation] Tocilizumab Ameliorates Vascular Inflammation and Clinical Symptoms in Patients With Takayasu Arteritis Refractotry to Glucocorticoids2013
- Author(s)
  Yoshikazu Nakaoka, Kaori Higuchi, Yoh Arita, Takahiro Kataoka, Taku Yasui, Kuniyasu Ikeoka, Tomohito Ohtani, Yasushi Sakata, Keiko Yamauchi-Takihara, Issei Komuro
- Organizer
  ACC.13
- Place of Presentation
  モスコンセンター(アメリカ合衆国・サンフランシスコ)
- Year and Date
  2013-03-09
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] 低酸素誘発性肺高血圧モデルでIL-6/Th17細胞シグナルは肺血管リモデリングに必須である2013
- Author(s)
  片岡　崇弘、中岡良和、曽野部崇、保仙　直毅、稲垣　薫克、樋口香織、有田陽、安居琢、池岡邦泰、正木　豪、瀧原圭子、白井幹康、小室一成
- Organizer
  第4回Molecular Cardiovascular ConferenceII
- Place of Presentation
  キロロリゾートホテルピアノ(北海道余市郡赤井川村)
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] Tocilizumab Ameliorates Vascular Inflammation and Clinical Symptoms in the Patients with Takayasu Arteritis Refractory to Glucocorticoids2013
- Author(s)
  Nakaoka Y, Arita Y, Higuchi K, Hashimoto-Kataoka T, Yasui T, Sakata Y, Yamauchi-Takihara K, Kishimoto T, Komuro I
- Organizer
  第30回国際心臓研究学会(ISHR)日本部会総会
- Place of Presentation
  La Valencia Hotel(アメリカ合衆国・サンディエゴ)
- Year and Date
  2013-06-29
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] Endothelial Gab1 deletion accelerates angiotensin II-dependent vascular inflammation and2012
- Author(s)
  Nakaoka Y
- Organizer
  17th International Vascular Biology Meeting 2012
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] ENdothelial Gab1 deletion accelerates angiotensin II-dependent vascular inflammation and atherosclerosis in apolipoprotein E knockout mice2012
- Author(s)
  Nakaoka Y
- Organizer
  17th International Vascular Biology Meeting 2012
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-24659391
[Presentation] ENdothelial Gab1 deletion accelerates angiotensin II-dependent vascular inflammation andatherosclerosis in apolipoprotein E knockout mice2012
- Author(s)
  Nakaoka Y
- Organizer
  17th International Vascular Biology Meeting 2012
- Place of Presentation
  Wiesbaden, Germany
- Data Source
  KAKENHI-PROJECT-24659391
[Presentation] Endothelial Gab1Deletion Accelerates Angiotensin II-Dependent Vascular Inflammation and Atherosclerosis inApoE Knockout Mice2011
- Author(s)
  Nakaoka Y, Higuchi K, Shioyama W, Arita Y, Hashimoto T, Yasui T, Ikeoka K, Kuroda T, Nishida K, Fujio, Y Yamauchi-Takihara K, Shirai M, Mochizuki N, Komuro I.
- Organizer
  第28回　International Society of Heart Research 日本部会総会
- Place of Presentation
  学術総合センター、東京都
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] Gab1 Negatively regulates Angiotensin II-accelerated Atherosclerosis in Apolipoprotein E Deficient Mice2011
- Author(s)
  Nakaoka Y, Higuchi K, Shioyama W, Taniyama Y, Arita Y, Hashimoto T, Fujio Y, Yamauchi-Takihara K, Morishita R, Hirano T, Komuro I
- Organizer
  第75回日本循環器学会学術集会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2011-08-04
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] The Role of Gab Familyl Docking Proteins in the Pathophysiology of the Cardiovascular Diseases2011
- Author(s)
  Yoshikazu Nakaoka
- Organizer
  The 12th US-Japan-Asia Dialogue on Cardiovascular Diseases and Young Investigator Competition (Pfizer)
- Place of Presentation
  高輪プリンスホテル(東京都)(Keynote Lecture)(招待講演)
- Year and Date
  2011-07-31
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] 心筋から分泌されるアンジオポイエチン1は冠静脈の形成に必須である2011
- Author(s)
  有田陽、中岡良和、白井学、有馬勇一郎、樋口香織、橋本崇弘、池岡邦泰、安居琢、瀧原圭子、西山功一、山岸敬幸、栗原裕基、小室一成
- Organizer
  第2回MCC II
- Place of Presentation
  ホテルピアノ(北海道余市郡赤井川村)
- Year and Date
  2011-09-04
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] Endothelial Gab1Deletion Accelerates Angiotensin II-Dependent Vascular Inflammation and Atherosclerosis in ApoE Knockout Mice2011
- Author(s)
  Yoshikazu Nakaoka, Kaori Higuchi, Wataru Shimoyama, Yoh Arita, Takahiro Hashimoto, Tadashi Kuroda, Yasushi Fujio, Keiko Takihara, Issei Komuro
- Organizer
  第28回ISHR日本部会総会
- Place of Presentation
  学術総合センター(東京都)(ポスター発表)
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] The Role of Gab Familyl Docking Proteins in the Pathophysiology of the Cardiovascular Diseases2011
- Author(s)
  Nakaoka Y
- Organizer
  The 12th US-Japan-Asia Dialogue on Cardiovascular Diseases and Young Investigator Competition (Pfizer)
- Place of Presentation
  高輪プリンスホテル(東京都)
- Year and Date
  2011-07-31
- Invited
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] The Role of Gab Familyl Docking Proteins in the Pathophysiology of the Cardiovascular Diseases2011
- Author(s)
  Nakaoka Y
- Organizer
  The 12th US-Japan-Asia Dialogue on Cardiovascular Diseases and Young Investigator Competition(Pfizer)
- Place of Presentation
  高輪プリンスホテル(東京都)
- Year and Date
  2011-07-31
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] Gab1 is an essential component for postnatal angiogenesis after ischemia via HGF/c-Met signaling2011
- Author(s)
  Nakaoka Y.
- Organizer
  The 9th Japan-Korea Joint Symposium on Vascular Biology(招待講演)
- Place of Presentation
  Busan,Korea
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] The Role of Gab Familyl Docking Proteins in the Pathophysiology of the Cardiovascular Diseases (Keynote lecture)2011
- Author(s)
  Nakaoka Y.
- Organizer
  The 12th US-Japan-Asia Dialogue on Cardiovascular Diseases and Young Investigator Competition(招待講演)
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] 心筋から分泌されるアンジオポイエチン1は冠静脈の形成に必須である2011
- Author(s)
  有田陽、中岡良和、白井学、有馬勇一郎、樋口香織、橋本崇弘、池岡邦泰、安居琢、瀧原圭子、西山功一、山岸敬幸、栗原裕基、小室一成
- Organizer
  第2回MCC II
- Place of Presentation
  ホテルピアノ(北海道余市郡赤井川村)
- Year and Date
  2011-09-04
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] Gab1 Negatively regulates Angiotensin II-accelerated Atherosclerosis in Apolipoprotein E Deficient Mice2011
- Author(s)
  Nakaoka Y, Higuchi K, Shioyama W, Taniyama Y, Arita Y, Hashimoto T, Fujio Y, Yamauchi-Takihara K, Morishita R, Hirano T, Komuro I
- Organizer
  第75回日本循環器学会学術集会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2011-08-04
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] Blockade of interleukin-6 Signaling Prevents Hypoxia-induced Pulmonary Arterial Hypertension in Mice2011
- Author(s)
  Takahiro Hashimoto, Yoshikazu Nakaoka, Takashi Sonobe, Yoh Arita, Kuniyasu Ikeoka, Mikiyasu Shirai, Issei Komuro
- Organizer
  第19回日本血管生物医学会学術集会
- Place of Presentation
  東京ステーションコンファレンス(東京都)(ポスター発表)
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] Gab1 is Critically involved in HGF-dependent Postnatal Angiogenesis after ischemia2011
- Author(s)
  Shioyama W, Nakaoka Y, Higuchi K, Minami T, Nishida K, Taniyama Y, Kidoya H, Arita Y, Hashimoto T, Fujio Y, Shirai M, Takakura N, Morishita R, Yamauchi-Takihara K, Kodama T, Hirano T, Mochizuki N, Komuro I
- Organizer
  日本循環器学会
- Place of Presentation
  京都国際会館(京都府)
- Year and Date
  2011-03-15
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] Blockade of interleukin-6 Signaling Prevents Hypoxia-induced Pulmonary Arterial Hypertension in Mice2011
- Author(s)
  Hashimoto T, Nakaoka Y, Sonobe T, Arita Y, Ikeoka K, Shirai M, Komuro I
- Organizer
  第19回日本血管生物医学会学術集会
- Place of Presentation
  東京ステーションコンファレンス(東京都)
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] Gab1 is an essential component for postnatal angiogenesis after ischemia via HGF/ c-Met signaling2011
- Author(s)
  Nakaoka Y
- Organizer
  The 9th Japan-Korea Joint Symposium on Vascular Biology 2011
- Place of Presentation
  釜山ウェスティンホテル(韓国・釜山)
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] Gab1 Negatively regulates Angiotensin II-accelerated Atherosclerosis in Apolipoprotein E Deficient Mice（FRS）2011
- Author(s)
  Nakaoka Y, Higuchi K, Shioyama W, Arita Y, Hashimoto T, Yasui T, Ikeoka K, Kuroda T, Nishida K, Fujio, Y Yamauchi-Takihara K, Shirai M, Mochizuki N, Komuro I.
- Organizer
  第75回　日本循環器学会学術集会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] Gab1 Negatively regulates Angiotensin II-accelerated Atherosclerosis in Apolipoprotein E Deficient Mice2011
- Author(s)
  Yoshikazu Nakaoka, Kaori Higuchi, Wataru Shioyama, Yoshiaki Taniyama, Yoh Arita, Takahiro Hashimoto, Yasushi Fujio, Keiko Yamauchi-Takihara, Ryuichi Morishita, Toshio Hirano, Issei Komuro
- Organizer
  第75回日本循環器学会学術集会
- Place of Presentation
  パシフィコ横浜(横浜市)(Featured Research Session)
- Year and Date
  2011-08-04
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] 心筋から分泌されるアンジオポイエチン1は冠静脈の形成に必須である2011
- Author(s)
  有田陽、中岡良和、白井学、有馬勇一郎、樋口香織、橋本崇弘、池岡邦泰、安居琢、瀧原圭子、西山功一、山岸敬幸、栗原裕基、小室一成
- Organizer
  第2回Molecular Cardiovascular Conerence II
- Place of Presentation
  ホテルピアノ(北海道余市郡赤井川村)(口頭発表)
- Year and Date
  2011-09-04
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] Gab1 is an essential component for postnatal angiogenesis after ischemia via HGF/c-Met signaling2011
- Author(s)
  Nakaoka Y
- Organizer
  The 9th Japan-Korea Joint Symposium on Vascular Biology 2011
- Place of Presentation
  釜山ウェスティンホテル(韓国・釜山)
- Year and Date
  2011-08-26
- Invited
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] Gab1 is an essential component for postnatal angiogenesis after ischemia via HGF/c-Met signaling2011
- Author(s)
  Yoshikazu Nakaoka
- Organizer
  The 9th Japan-Korea Joint Symposium on Vascular Biology 2011
- Place of Presentation
  釜山ウェスティンホテル(韓国・釜山)(招待講演Young Faculty Symposium on Vascular Biology)
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] SHP2 mediates gp130-dependent cardiomyocyte hypertrophy via negative regulation of skeletal alpha-actin gene2010
- Author(s)
  Yoshikazu Nakaoka
- Organizer
  Basic Cardiovascular Sciences 2010 American Heart Association Scientific Sessions
- Place of Presentation
  Rancho Mirage, CA, USA
- Year and Date
  2010-07-20
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] Gab1 Negatively regulates Angiotensin II-accelerated Atherosclerosis in Apolipoprotein E Deficient Mice2010
- Author(s)
  Higuchi K, Nakaoka Y, Shioyama W, TaniyamaY, Arita Y, Hashimoto T, Fujio Y, Yamauchi-Takihara K, Morishita R, Hirano T, Komuro I
- Organizer
  2010 American Heart Association Scientific Sessions
- Place of Presentation
  米国・シカゴ
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] SHP2 mediates gp130-dependent cardiomyocyte hypertrophy via negative regulation of skeletal alpha-actin gene2010
- Author(s)
  Nakaoka Y
- Organizer
  Basic Cardiovascular Sciences 2010 American Heart Association Scientific Sessions
- Place of Presentation
  米国・カリフォルニア州、Rancho Mirage
- Year and Date
  2010-07-20
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] Scaffolding Docking Protein Gab1 Has an Essential Role for HGF-dependent Endothelial Signaling and Angiogenesis after Hindlimb Ischemia2009
- Author(s)
  Nakaoka Y. Shioyama W., Higuchi K, Minami T, Nishida K, Taniyama Y, Kidoya H, Arita Y, Hashimoto T, Fujio Y, Shirai M, Takakura N, Morishita R, Yamauchi-Takihara K, Kodama T, Hirano T, Mochizuki N, Komuro I
- Organizer
  Basic Cardiovascular Sciences Conference 2009 : Molecular Mechanisms of Cardiovascular Disease
- Place of Presentation
  The Ritz-Carlton in Lake Las Vegas,米国ネバダ州ラスベガス)
- Year and Date
  2009-07-22
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] Protein Gab1 is Essential for HGF-dependent Endothelial Signaling and Angiogenesis after Hindlimb Ischemia2009
- Author(s)
  Shioyama W, Higuchi K, Hiramoto Y, Arita Y, Kuroda T, Fujio Y, Sanada F, Taniyama Y, Morishita R, Yamauchi-Takihara K, Hirano T, Hori M, Mochizuki N, and Nakaoka Y. Docking
- Organizer
  第73回日本循環器学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590844
[Presentation] Interaction of Docking Protein Gab1 with Tyrosine Phosphatase SHP2 Regulates Hepatocyte Growth Factor-dependent ERK5 Activation and Upregulation of Kruppel-like Factor 2 in the Vascular Endothelium2009
- Author(s)
  Shioyama W., Nakaoka Y., et al.
- Organizer
  American Heart Association, Scientific Sessions 2009
- Place of Presentation
  Orange County Convention Center, Orlando, FL, USA
- Year and Date
  2009-11-18
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] Interaction of Docking Protein Gab1 with Tyrosine Phosphatase SHP2 Regulates Hepatocyte Growth Factor-dependent ERK5 Activation and Upregulation of Kruppel-like Factor 2 in the Vascular Endothelium2009
- Author(s)
  Shioyama W., Nakaoka Y. Higuchi K, Minami T, Nishida K, Taniyama Y, Kidoya H, Arita Y, Hashimoto T, Fujio Y, Shirai M, Takakura N, Morishita R, Yamauchi-Takihara K, Kodama T, Hirano T, Mochizuki N, Komuro I
- Organizer
  American Heart Association, Scientific Sessions 2009
- Place of Presentation
  Orange County ConventionCenter(米国・フロリダ州オーランド)
- Year and Date
  2009-11-18
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] The Novel Downstream Target of Neuregulin-1-ErbB Signaling Pathway for Maintenance of Cardiac Function~Implication for New Treatment of Heart Failure~Symposium 82009
- Author(s)
  Nakaoka Y.
- Organizer
  第73回日本循環器学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590844
[Presentation] Scaffolding Docking Protein Gab1 Has an Essential Role for HGF-depen dent Endothelial Signaling and Angiogenesis after Hindlimb Ischemia2009
- Author(s)
  Nakaoka Y., et al.
- Organizer
  Basic Cardiovascular Sciences Conference 2009 : Molecular Mechanisms of Cardiovascular Disease
- Place of Presentation
  The Ritz-Carlton in Lake Las Vegas, NV, USA
- Year and Date
  2009-07-22
- Data Source
  KAKENHI-PROJECT-21590930
[Presentation] The Novel Downstream Target of Neuregulin-1/ErbB Signaling Pathway For Maintenance of Cardiac Function2009
- Author(s)
  Nakaoka Y.
- Organizer
  第73回日本循環器学会 (シンポジウム8)
- Place of Presentation
  大阪国際会議場、大阪、日本
- Year and Date
  2009-03-21
- Data Source
  KAKENHI-PROJECT-19590844
[Presentation] SHP2 Negatively Regulates Skeletal alpha-actin Gene Expression Downstream of LIF-dependent2008
- Author(s)
  Shioyama W, Nakaoka Y, Fujio Y, Yamauchi-Takihara K, Mochizuki N.
- Organizer
  Hypertrophic Signaling in Cardiomyocytes ISHR Japanese Section
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590844
[Presentation] Interaction of Scaffolding Adaptor Protein Gab1 with Tyrosine Phosphatase SHP2 Negatively Regulates IGF-I-dependent Myogenic Differentiation via ERK1/2 Signaling 0Pathway2008
- Author(s)
  Nakaoka Y, Koyama T, Okamoto K,Shioyama W, Fujio Y, Hirano T, Mochizuki N.
- Organizer
  Basic Cardiovascular Sciences Conference 2008 Heart Failure : Molecular Mechanisms and Therapeutic Targets
- Place of Presentation
  Keystone
- Data Source
  KAKENHI-PROJECT-19590844
[Presentation] Scaffolding Docking Protein Gab1 is Essential for HGF-dependent Endothelial Signaling and Angiogenesis after Hindlimb Ischemia2008
- Author(s)
  Shioyama W, Higuchi K, Okamoto K, Arita Y, Sanada F, Taniyama Y, Morishita R, Kuroda T, Fujio Y, Yamauchi-Takihara K, Mochizuki N, Nakaoka Y.
- Organizer
  American Heart Association Scientific Sessions 2008
- Place of Presentation
  New Ohleans
- Data Source
  KAKENHI-PROJECT-19590844
[Presentation] Interaction of Scaffolding Adaptor Protein Gab1 with Tyrosine Phosphatase SHP2 Negatively Regulates IGF-I-dependent Myogenic Differentiation via ERK1/2 Signaling Pathway2008
- Author(s)
  Nakaoka Y., et al.
- Organizer
  Basic Cardiovascular Sciences Conference 2008
- Place of Presentation
  キーストン、コロラド州、米国
- Year and Date
  2008-07-29
- Data Source
  KAKENHI-PROJECT-19590844
[Presentation] ドッキング蛋白質Gab1 は下肢虚血ストレス後の血管新生に必須である2008
- Author(s)
  中岡良和、樋口香織、塩山渉、岡本紀太郎、有田陽、黒田忠、眞田文博、谷山義明、森下竜一、藤尾慈、瀧原圭子、平野俊夫、望月直樹
- Organizer
  第12回Molecular Cardiovascular Conference
- Place of Presentation
  北海道余市郡赤井川村
- Year and Date
  2008-09-05
- Data Source
  KAKENHI-PROJECT-19590844
[Presentation] Essential role of Gab2 for Angiopoietin-1/Tie2-dependent Signaling and Cytoprotection in the Endothelial Cells2008
- Author(s)
  Okamoto K, Shioyama W, Higuchi K, Kuroda T, Fujio Y, Yamauchi-Takihara K, Hori M, Koh GY, Mochizuki N, Nakaoka Y.
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590844
[Presentation] Gab Family Scaffolding Adaptors are Essential for Cardiac Maintenance via Transmitting Endothelial-Myocardial Crosstalk2008
- Author(s)
  Nakaoka Y, and Mochizuki N.
- Organizer
  Keystone Symposia Molecular Mechanism of Angiogenesis in Development and Disease
- Place of Presentation
  Vancouver
- Data Source
  KAKENHI-PROJECT-19590844
[Presentation] Gab Family Scaffolding Adaptors Are Essential for Cardiac Maintenance via Transmitting Endothelial-Myocardial Crosstalk2008
- Author(s)
  Nakaoka Y., et. al.
- Organizer
  Keystone Symposia Molecular Mechanisms of Angiogenesis in Development and Disease
- Place of Presentation
  Fairmont Hotel,バンクーバー、BC、カナダ
- Year and Date
  2008-01-18
- Data Source
  KAKENHI-PROJECT-19590844
[Presentation] Gab Family Scaffolding Adaptor Proteins are Essential for Postnatal Maintenance of Cardiac Function via Neuregulin-1/ErbB Signaling2007
- Author(s)
  Nakaoka Y, Minami T, Sawa H, Fujio Y, Koyama T, Hirota H, Yamauchi-Takihara K, Otsu K, Hirano T, and Mochizuki N.
- Organizer
  American Heart Association Scientific Sessions 2007
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-19590844
[Presentation] Gab Family Scaffolding Adaptor Proteins are Essential for Postnatal Maintenance of Cardiac Fuction via Neuregulin-1/ErbB Signaling2007
- Author(s)
  Nakaoka Y., et. al.
- Organizer
  American Heart Association, Scientific Sessions 2007
- Place of Presentation
  オーランド、フロリダ、米国
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-19590844
[Presentation] 抗Interleukin-6(IL-6)受容体抗体によるIL-6阻害療法は低酸素誘発性肺高血圧の病態形成を抑制する
- Author(s)
  中岡良和、橋本崇弘、曽野部崇、瀧原圭子、白井幹康、小室一成
- Organizer
  第2回日本肺循環学会学術集会
- Place of Presentation
  東京ステーションコンファレンス(東京都千代田区)
- Invited
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] 血管形成研究の最前線「冠静脈形成の分子機構
- Author(s)
  中岡良和、有田陽、松永太一、山下潤、小室一成
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  千里阪急ホテル(大阪府豊中市)
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] Tocilizumab Ameliorates Vascular Inflammation and Clinical Symptoms in the Patients with Takayasu Arteritis Refractory to Glucocorticoids
- Author(s)
  Yoshikazu Nakaoka, Yoh Arita, Kaori Higuchi, Takahiro Hashimoto-Kataoka, Taku Yasui, Yasushi Sakata, Keiko Yamauchi-Takihara, Tadamitsu Kishimoto, Issei Komuro
- Organizer
  第30回国際心臓研究学会（ISHR）日本部会総会
- Place of Presentation
  La Valencia Hotel, San Diego, USA
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] 抗Interleukin-6(IL-6)受容体抗体によるIL-6阻害療法は低酸素誘発性肺高血圧の病態形成を抑制する
- Author(s)
  中岡良和、橋本崇弘、曽野部崇、瀧原圭子、白井幹康、小室一成
- Organizer
  第2回日本肺循環学会学術集会
- Place of Presentation
  東京ステーションコンファレンス(東京都千代田区)
- Invited
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] Angiopoietin-1 is essential for coronary venogenesis in the developing heart
- Author(s)
  中岡　良和
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Invited
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] Tocilizumab Ameliorates Vascular Inflammation and Clinical Symptoms in the Patients with Takayasu Arteritis Refractory to Glucocorticoids
- Author(s)
  Yoshikazu Nakaoka, Kaori Higuchi, Yoh Arita, Taku Yasui, Kuniyasu Ikeoka, Takeshi　Masaki,Tomohito Ohtani, Keiko Yamauchi-Takihara, Yasushi Sakata, Issei Komuro
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム(東京都千代田区)
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] Interleukin-6 promotes hypoxia-induced pulmonary arterial hypertension through Th17 response and alternative activation of macrophages
- Author(s)
  Yoshikazu Nakaoka
- Organizer
  8th International Kloster Seeon Meeting
- Place of Presentation
  Kloster Seeon(ドイツ・バイエルン州）
- Year and Date
  2014-09-20 – 2014-09-23
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] 冠静脈形成の分子機構
- Author(s)
  中岡良和、有田陽、松永太一、山下潤、小室一成
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  千里阪急ホテル(大阪府豊中市)
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] Interleukin-6 promotes hypoxia-induced pulmonary arterial hypertension through Th17 response and alternative activation of macrophages
- Author(s)
  Yoshikazu Nakaoka
- Organizer
  8th International Kloster Seeon Meeting
- Place of Presentation
  Kloster Seeon(ドイツ・バイエルン州）
- Year and Date
  2014-09-20 – 2014-09-23
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] Tocilizumab Ameliorates Vascular Inflammation and Clinical Symptoms in the Patients with Takayasu Arteritis Refractory to Glucocorticoids
- Author(s)
  Yoshikazu Nakaoka, Yoh Arita, Kaori Higuchi, Takahiro Hashimoto-Kataoka, Taku Yasui, Yasushi Sakata, Keiko Yamauchi-Takihara, Tadamitsu Kishimoto, Issei Komuro
- Organizer
  第30回国際心臓研究学会（ISHR）日本部会総会
- Place of Presentation
  La Valencia Hotel, San Diego, USA
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] 心筋由来のAngiopoietin-1は静脈洞内皮細胞の遊走と静脈分化の促進を通して冠静脈
- Author(s)
  中岡良和、有田陽、小室一成
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市)
- Invited
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] 心臓における冠血管発生
- Author(s)
  中岡　良和
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Invited
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] 心臓における冠血管発生
- Author(s)
  中岡　良和
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Invited
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] 心筋由来のAngiopoietin-1は静脈洞内皮細胞の遊走と静脈分化の促進を通して冠静脈
- Author(s)
  中岡良和、有田陽、小室一成
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市)
- Invited
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] Angiopoietin-1 is essential for coronary venogenesis in the developing heart
- Author(s)
  中岡　良和
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Invited
- Data Source
  KAKENHI-PROJECT-23591101
[Presentation] Tocilizumab Ameliorates Vascular Inflammation and Clinical Symptoms in the Patients with Takayasu Arteritis Refractory to Glucocorticoids
- Author(s)
  Yoshikazu Nakaoka, Kaori Higuchi, Yoh Arita, Taku Yasui, Kuniyasu Ikeoka, Takeshi　Masaki,Tomohito Ohtani, Keiko Yamauchi-Takihara, Yasushi Sakata, Issei Komuro
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム(東京都千代田区)
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] 血管形成研究の最前線「冠静脈形成の分子機構
- Author(s)
  中岡良和、有田陽、松永太一、山下潤、小室一成
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  千里阪急ホテル(大阪府豊中市)
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] 血管平滑筋細胞由来のアンジオポエチン１は下肢虚血血管新生時の動脈化に重要である
- Author(s)
  池岡邦泰、中岡良和、曽野部崇、白井幹康、樋口香織、有田陽、片岡崇弘、安居琢、正木豪、瀧原圭子、小室一成
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  千里阪急ホテル(大阪府豊中市)
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] 血管平滑筋細胞由来のアンジオポエチン１は下肢虚血血管新生時の動脈化に重要である
- Author(s)
  池岡邦泰、中岡良和、曽野部崇、白井幹康、樋口香織、有田陽、片岡崇弘、安居琢、正木豪、瀧原圭子、小室一成
- Organizer
  第4回Molecular Cardiovascular ConferenceII
- Place of Presentation
  キロロリゾートホテルピアノ(北海道余市郡赤井川村)
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] 抗Interleukin-6(IL-6)受容体抗体によるIL-6阻害療法は低酸素誘発性肺高血圧の病態形成を抑制する
- Author(s)
  中岡良和、橋本崇弘、曽野部崇、瀧原圭子、白井幹康、小室一成
- Organizer
  第2回日本肺循環学会学術集会
- Place of Presentation
  東京ステーションコンファレンス(東京都千代田区)
- Invited
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] アンギオポイエチン1は静脈洞の未分化血管内皮細胞を遊走・分化させ冠静脈形成に必須の因子である
- Author(s)
  有田陽、中岡良和、松永太一、木戸屋浩康、橋本崇弘、池岡邦泰、高倉伸幸、望月直樹、山下潤、小室一成
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  千里阪急ホテル(大阪府豊中市)
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] Angiopoietin-1 is essential for coronary venogenesis in the developing heart
- Author(s)
  中岡　良和
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Invited
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] Angiopoietin-1 Derived from Vascular Smooth Muscle Cells is Essential for Arteriogenesis after Hindlimb Ischemia
- Author(s)
  Kuniyasu Ikeoka, Yoshikazu Nakaoka, Takashi Sonobe, Kaori Higuchi, Yoh Arita, Takahiro　Hashimoto-Kataoka, Taku Yasui, Takeshi Masaki, Stephan Offermans, Keiko Yamauchi-Takihara, Mikiyasu Shirai, Issei Komuro
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム(東京都千代田区)
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] Angiopoietin-1 secreted from myocardium is essential for the formation of coronary veins in the developing heart
- Author(s)
  Yoh Arita, Yoshikazu Nakaoka, Taichi Matsunaga, Hiroyasu Kidoya, Kohei Yamamizu, Yuichiro Arima, Kaori Higuchi, Takahiro Hashimoto, Kuniyasu Ikeoka, Taku Yasui, Koichi Nishiyama, Hiroki Kurihara, Keiko Yamauchi-Takihara, Hiroyuki Yamagishi, Nobuyuki Takakura, Naoki Mochizuki, Gou Young
- Organizer
  第30回国際心臓研究学会(ISHR)日本部会総会
- Place of Presentation
  La Valencia Hotel, San Diego, USA
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] Blockade of interleukin-6 signaling might be a promising therapeutic option for pulmonary arterial hypertension via regulating Th17 cell differentiation
- Author(s)
  Takahiro Hashimoto-Kataoka, Yoshikazu Nakaoka, Takashi Sonobe, Naoki Hosen, Yoh Arita, Taku Yasui, Kuniyasu Ikeoka, Takeshi Masaki, Tadakatsu Inagaki, Keiko Yamauchi-Takihara, Mikiyasu Shirai, Issei Komuro
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム(東京都千代田区)
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] Tocilizumab Ameliorates Vascular Inflammation and Clinical Symptoms in the Patients with Takayasu Arteritis Refractory to Glucocorticoids
- Author(s)
  Yoshikazu Nakaoka, Yoh Arita, Kaori Higuchi, Takahiro Hashimoto-Kataoka, Taku Yasui, Yasushi Sakata, Keiko Yamauchi-Takihara, Tadamitsu Kishimoto, Issei Komuro
- Organizer
  第30回国際心臓研究学会（ISHR）日本部会総会
- Place of Presentation
  La Valencia Hotel, San Diego, USA
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] 心筋由来のAngiopoietin-1は静脈洞内皮細胞の遊走と静脈分化の促進を通して冠静脈
- Author(s)
  中岡良和、有田陽、小室一成
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市)
- Invited
- Data Source
  KAKENHI-PROJECT-25670386
[Presentation] 心臓における冠血管発生
- Author(s)
  中岡　良和
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Invited
- Data Source
  KAKENHI-PROJECT-25293183
[Presentation] Tocilizumab Ameliorates Vascular Inflammation and Clinical Symptoms in the Patients with Takayasu Arteritis Refractory to Glucocorticoids
- Author(s)
  Yoshikazu Nakaoka, Kaori Higuchi, Yoh Arita, Taku Yasui, Kuniyasu Ikeoka, Takeshi　Masaki,Tomohito Ohtani, Keiko Yamauchi-Takihara, Yasushi Sakata, Issei Komuro
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム(東京都千代田区)
- Data Source
  KAKENHI-PROJECT-23591101

1. SHIRAI Mikiyasu (70162758)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. Makoto Okazawa (40414130)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KOMURO Issei (30260483)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
4. MOCHIZUKI Naoki (30311426)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. KURODA TADASHI (60403078)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. FUJIO Yasushi (20359839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. NAKAYAMA Hiroyuki (40581062)

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40. Ueno Naoko

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41. Eguchi Kazuo

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Nakaoka Yoshikazu 中岡 良和

NAKAOKA Yoshikazu 中岡 良和

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Elucidating the molecular pathogenesis of CTD-associated PAHPrincipal Investigator

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The Pathogenesis of pulmonary arterial hypertension via aryl hydrocarbon receptorPrincipal Investigator

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Elucidation of the molecular pathogenesis of pulmonary hypertension via inflammatory cytokinesPrincipal Investigator

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Molecular mechanism of Vasculitis and Pulmonary arterial hypertension via inflammatory cytokinesPrincipal Investigator

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Angiopoietin-1-mediated vascular development and maturation in the developing heartPrincipal Investigator

Nakaoka Yoshikazu 中岡良和

NAKAOKA Yoshikazu 中岡良和

[Book] 免疫・炎症病態×治療研究Update　 Physician Scientistが拓く世界2019