Nishimoto Arata 西本新

… Alternative Names

Researcher Number	90396325
Other IDs
External Links
Affiliation (Current)	2019: 山口大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2017: 山口大学, 大学院医学系研究科, 助教 2016: 山口大学, 医学(系)研究科(研究院), 助教 2014 – 2015: 山口大学, 医学部附属病院, 助教 2012 – 2013: 山口大学, 医学(系)研究科(研究院), 助教 2007 – 2011: 北海道大学, 大学院・医学研究科, 助教 2005: 北海道大学, 遺伝子病制御研究所, 非常勤研究員
Review Section/Research Field	Principal Investigator General pharmacology / Digestive surgery Except Principal Investigator General pharmacology / Respiratory surgery / Biological Sciences / Digestive surgery
Keywords	Principal Investigator 酵母ツーハイブリッド法 / エンドセリン受容体 / Jab1 / 蛋白質分解 / ユビキチン化 / エンドサイトーシス / ヒト大腸癌細胞 / JAB1 / STAT3 / 蛋白質間相互作用 / STAT3標的DNA結合能 / STAT3 DNA結合能 / HIF-1 … More Except Principal Investigator … More

Mechanisms of enhanced tumor growth during compensatory lung growth after major lung resection
- Principal Investigator
  
  UEDA Kazuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Yamaguchi University
c-MYC, HIF-1による大腸癌の抗癌剤抵抗性獲得機構の解明
- Principal Investigator
  
  榎忠彦
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
Mechanism identification and Developing a novel method for therapy against lung cancer invasion via cancer-associated fibroblasts in pulmonary emphysema
- Principal Investigator
  
  HAYASHI Masataro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Yamaguchi University
Elucidation of the role of Jab1 in malignant progression of colon cancerPrincipal Investigator
- Principal Investigator
  
  NISHIMOTO Arata
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Yamaguchi University
Study of the regulatory mechanism of ETAR and ETBR level by receptor binding protein and the relevance between clinical significance and endothelin receptor level.
- Principal Investigator
  
  MIWA Soichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Hokkaido University
Elucidation for pathophysiological significance of Jab1 as an inducer of endothelin type A receptor degradation in cardiovascular diseasesPrincipal Investigator
- Principal Investigator
  
  NISHIMOTO Arata
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Hokkaido University
Search for novel signal molecules which are directly activated by endothelin receptor
- Principal Investigator
  
  MIWA Soichi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Hokkaido University
miRNAによって引き起されるHOX遺伝子ネットワークの癌特異的破綻
- Principal Investigator
  
  浜田淳一
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University

All 2016 2015 2014 2013 2012 2010 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Enhanced tumor growth in the remaining lung after major lung resection2016
- Author(s)
  Fumiho Sano, Kazuhiro Ueda, Junichi Murakami, Masataro Hayashi, Arata Nishimoto, Kimikazu Hamano
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 202 Pages: 1-7
- DOI
  10.1016/j.jss.2015.12.012
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10259
[Journal Article] Pulmonary emphysema and tumor microenvironment in primary lung cancer2016
- Author(s)
  Murakami J, Ueda K, Sano F, Hayashi M, Nishimoto A, Hamano K
- Journal Title
  
  Journal of surgical research
  
  Volume: 200 Pages: 690-697
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462177
[Journal Article] The c-MYC-ABCB5 axis plays a pivotal role in 5-fluorouracil resistance in human colon cancer cells.2015
- Author(s)
  Kugimiya Naruji, Nishimoto Arata, Hosoyama Tohru, Ueno Koji, Enoki Tadahiko, Li Tao-Sheng, Hamano Kimikazu
- Journal Title
  
  Journal of Cellular and Molecular Medicine
  
  Volume: 19 Pages: 1569-1581
- DOI
  10.1111/jcmm.12531
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462017, KAKENHI-PROJECT-15H02654
[Journal Article] Hypoxic preconditioning reinforces cellular functions of autologous peripheral blood-derived cells in rabbit hindlimb ischemia model2014
- Author(s)
  Kudo T, Hosoyama T, Samura M, Katsura S, Nishimoto A, Kugimiya N, Fujii Y, Li TS, Hamano K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 444(3) Pages: 370-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791425
[Journal Article] HIF-1α activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells2014
- Author(s)
  Nishimoto A, Kugimiya N, Hosoyama T, Enoki T, Li TS, Hamano K
- Journal Title
  
  Int J Oncol
  
  Volume: 44(6) Pages: 2077-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791425
[Journal Article] HIF-1α activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells.2014
- Author(s)
  Nishimoto A, Kugimiya N, Hosoyama T, Enoki T, Li TS, Hamano K
- Journal Title
  
  Int. J. Oncol.
  
  Volume: 44 Pages: 2077-2084
- DOI
  10.3892/ijo.2014.2367
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24791425, KAKENHI-PROJECT-26462017
[Journal Article] Significant role of bone marrow-derived cells in compensatory regenerative lung growth2013
- Author(s)
  Suga A, Ueda K, Takemoto Y, Nishimoto A, Hosoyama T, Li TS, Hamano K
- Journal Title
  
  J Surg Res
  
  Volume: 183(1) Pages: 84-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791425
[Journal Article] JAB1 regulates unphosphorylated STAT3 DNA-binding activity through protein-protein interaction in human colon cancer cells2013
- Author(s)
  Nishimoto A, Kugimiya N, Hosoyama T, Enoki T, Li TS, Hamano K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 438(3) Pages: 513-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791425
[Journal Article] JAB1 regulates unphosphorylated STAT3 DNA-binding activity through protein-protein interaction in human colon cancer cells2013
- Author(s)
  Nishimoto A, Kugimiya N, Hosoyama T, Enoki T, Li TS, Hamano K
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 438 Pages: 513-518
- DOI
  10.1016/j.bbrc.2013.07.105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791425
[Journal Article] Heat shock factor 1 contributes to ischemia-induced angiogenesis by regulating the mobilization and recruitment of bone marrow stem/progenitor cells2012
- Author(s)
  Kubo M, Li TS, Kurazumi H, Takemoto Y, Ohshima M, Yamamoto Y, Nishimoto A, Mikamo A, Fujimoto M, Nakai A, Hamano K
- Journal Title
  
  PLoS One
  
  Volume: 7(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791425
[Journal Article] Jab1 regulates levels of endothelin type A and B receptors by promoting ubiquitination and degradation.2010
- Author(s)
  Nishimoto A., Lu L., Hayashi M., Nishiya T., Horinouchi T. and Miwa S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 391 Pages: 1616-1622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article] Endothelin type Breceptor-induced sustained Ca2+ influx involves G(q/11)/phospholipase C-independent, p38 mitogen-activated protein kinase-dependent activation of Na+/H+ exchanger.2010
- Author(s)
  Higa T., Horinouchi T., Aoyagi H., Asano H., Nishiya T., Nishimoto A., Muramatsu I. and Miwa S.
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 113 Pages: 276-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article] Jab1 regulates levels of endothelin type A and B receptors by promoting ubiquitination and degradation2010
- Author(s)
  Nishimoto A., et al
- Journal Title
  
  Biochem Biophys Res Commun 391(4)
  
  Pages: 1616-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790237
[Journal Article] Jab1 regulates levels of endothelin type A and B receptors by promoting ubiquitination and degradation.2010
- Author(s)
  Nishimoto A, et al
- Journal Title
  
  Biochem Biophys Res Commun 391(4)
  
  Pages: 1616-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article] Jab1 regulates levels of endothelin type A and B receptors by promoting ubiquitination and degradation.2010
- Author(s)
  Nishimoto A, Lu L, Hayashi M, Nishiya T, Horinouchi T, Miwa S.
- Journal Title
  
  Biochem Biophys Res Commun. 391(4)
  
  Pages: 1616-1622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790237
[Journal Article] Endothelin type B receptor-induced sustained Ca2+ influx involves G(q/11)/phospholipase C-independent, p38 mitogen-activated protein kinase-dependent activation of Na+/H+ exchanger.2010
- Author(s)
  Higa T, Horinouchi T, Aoyagi H, Asano H, Nishiya T, Nishimoto A, Muramatsu I, Miwa S.
- Journal Title
  
  J Pharmacol Sci. 113(3)
  
  Pages: 276-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790237
[Journal Article] Differential coupling of human endothelin type A receptor to G(q/11) and G(12) proteins : the functional significance of receptor expression level in generating multiple receptor signaling.2009
- Author(s)
  Horinouchi T., Asano H., Higa T., Nishimoto A., Nishiya T., Muramatsu I. and Miwa S.
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 111 Pages: 338-351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390068
[Journal Article] Miwa S、Functional role of Na+/H+ exchanger in Ca2+ influx mediated via human endothelin type A receptor stably expressed in Chinese hamster ovary cells2008
- Author(s)
  Horinouchi T, Miyake Y, Nishiya T, Nishimoto A, Morishima S, Muramatsu I
- Journal Title
  
  J Pharmacol Sci 107(4)
  
  Pages: 456-459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] OCTN2VT, a splice variant of OCTN2, does not transport carnitine because of the retention in the endoplasmic reticulum caused by insertion of 24 amino acids in the first extracellular loop of OCTN22007
- Author(s)
  Maekawa S, Mori D, Nishiya T, Takikawa O, Horinouchi T, Nishimoto A, Kajita E, Miwa S
- Journal Title
  
  Biochim Biophys Acta (Mol Cell Res) 1773(6)
  
  Pages: 1000-1006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] Characterization of noradrenaline-induced increases in intracellular Ca^<2+> levels in Chinese hamster ovary cells stablyexpressing human α1A-adrenoceptor2007
- Author(s)
  Horinouchi T, Miyake Y, Nishiya T, Nishimoto A, Yorozu S, Jinno A, Kajita E, Miwa S
- Journal Title
  
  J Pharmacol Sci 105(1)
  
  Pages: 103-111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] Endothelin-1 decreases [Ca^<2+>]i via Na^+/Ca^<2+> exchanger in CHO cells stably expressing endothelin ETA receptor2007
- Author(s)
  Horinouchi T, Nishimoto A, Nishiya T, Lu L, Kajita E, Miwa S
- Journal Title
  
  Eur J Pharmacol 566(1-3)
  
  Pages: 28-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] 循環系調節因子としてのエンドセリンにより活性化される細胞内カルシウムシグナルとその調節系2007
- Author(s)
  三輪聡一、堀之内孝広、西本新、西屋禎
- Journal Title
  
  適応医学 11(2)
  
  Pages: 34-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Journal Article] Distinct roles of TIR and non-TIR regions in the subcellular localization and signaling properties of MyD882007
- Author(s)
  Nishiya T, Kajita E, Horinouchi T, Nishimoto A, Miwa S
- Journal Title
  
  FEBS Lett 581(17)
  
  Pages: 3223-3229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] JAB1 は蛋白質間相互作用を介してSTAT3 及びHIF-1α の標的DNAへの結合を安定化し抗アポトーシス活性を増強させる2013
- Author(s)
  西本新, 釘宮成二, 村上順一, 上田和弘, 濱野公一
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2013-10-05
- Data Source
  KAKENHI-PROJECT-24791425
[Presentation] Jab1 plays an important role in drug resistance by stabilizing STAT3 and HIF-1 DNA-binding2013
- Author(s)
  Arata Nishimoto
- Organizer
  9th AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Maui (HAWAII, USA)
- Data Source
  KAKENHI-PROJECT-24791425
[Presentation] Jab1 plays an important role in drug resistance by stabilizing STAT3 and HIF-1 DNA-binding2013
- Author(s)
  Arata Nishimoto, Naruji Kugimiya, Tohru Hosoyama, Tadahiko Enoki, Tao-Sheng Li, Kimikazu Hamano
- Organizer
  9th AACR-Japanese Cancer Association Joint Conference
- Place of Presentation
  Maui (Hawaii, USA)
- Data Source
  KAKENHI-PROJECT-24791425
[Presentation] JAB1は蛋白質間相互作用を介してSTAT3及び HIF-1αの標的DNAへの結合を安定化し抗アポトーシス活性を増強させる2013
- Author(s)
  西本　新、釘宮成二、村上順一、上田和弘、濱野公一
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜（パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-24791425
[Presentation] Jab1 はSTAT3 の標的DNA 配列に対する結合能を蛋白質間相互作用を介して正に制御する2012
- Author(s)
  西本新, 村上順一, 上田和弘
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌(ロイトン札幌)
- Data Source
  KAKENHI-PROJECT-24791425
[Presentation] Jab 1 positively regulates STAT3 DNA-binding activity through protein-protein interaction（Jab 1はSTAT3の標的DNA配列に対する結合能を蛋白質間相互作用を介して正に制御する）2012
- Author(s)
  西本　新
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌（札幌）
- Data Source
  KAKENHI-PROJECT-24791425
[Presentation] Regulation of endothelin receptor levels by receptor binding protein, Jab12010
- Author(s)
  西本新、Lu lingyun、林美里、西屋禎、堀之内孝広、三輪聡一
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪市)
- Data Source
  KAKENHI-PROJECT-21790237
[Presentation] Regulation of endothelin receptor levels by receptor binding protein, Jab12010
- Author(s)
  Nishimoto A.
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪府)
- Data Source
  KAKENHI-PROJECT-21390068
[Presentation] 受容体結合蛋白質によるエンドセリン受容体の発現レベル調節2009
- Author(s)
  西本新
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] Jab1, an ETAR-interacting protein, regulates ETAR level by promoting its degradation2009
- Author(s)
  西本新
- Organizer
  第26回国際心臓研究学会日本部会
- Place of Presentation
  北海道大学学術交流会館(札幌市)
- Data Source
  KAKENHI-PROJECT-21790237
[Presentation] 受容体結合蛋白質Jab1によるエンドセリン受容体の発現レベル調節機構2009
- Author(s)
  西本新、Lu lingyun、林美里、西屋禎、堀之内孝広、三輪聡一
- Organizer
  第60回日本薬理学会北部会
- Place of Presentation
  富山国際会議場(富山市)
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-21790237
[Presentation] Regulation of cell surface endothelin type A receptor level by a novel receptor-interacting protein, Jab12009
- Author(s)
  西本新
- Organizer
  第36回国際生理学会世界大会
- Place of Presentation
  京都国際会議場(京都市)
- Data Source
  KAKENHI-PROJECT-21790237
[Presentation] Jab1, a ETAR-interacting protein, regulates ETAR level by promoting its degradation2009
- Author(s)
  Nishimoto A.
- Organizer
  第26回国際心臓研究学会日本部会
- Place of Presentation
  北海道大学学術交流会館(北海道)
- Data Source
  KAKENHI-PROJECT-21390068
[Presentation] Regulation of cell surface endothelin type A receptor level by anovel receptor-interacting protein, Jabl2009
- Author(s)
  西本新
- Organizer
  第36回国際生理学会世界大会
- Place of Presentation
  京都国際会議場(京都府)
- Data Source
  KAKENHI-PROJECT-21390068
[Presentation] Regulation of cell surface endothelin type A receptor level by a novel receptor-interacting protein, Jab1.2009
- Author(s)
  西本新、Lu lingyun、林美里、西屋禎、堀之内孝広、三輪聡一
- Organizer
  第36回国際生理学会世界大会
- Place of Presentation
  京都国際会議場(京都市)
- Data Source
  KAKENHI-PROJECT-21790237
[Presentation] 受容体結合蛋白質Jab1によるエンドセリン受容体の発現レベル調節機構2009
- Author(s)
  西本新
- Organizer
  第60回日本薬理学会北部会
- Place of Presentation
  富山国際会議場(富山県)
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-21390068
[Presentation] Jab1, an ET_AR-interacting protein, regulates ET_AR level by promoting its degradation2009
- Author(s)
  Nishimoto A
- Organizer
  第26回国際心臓研究学会日本部会
- Place of Presentation
  北海道大学学術交流会館(北海道)
- Data Source
  KAKENHI-PROJECT-21390068
[Presentation] 受容体結合蛋白質Jab1によるエンドセリン受容体の発現レベル調節機構2009
- Author(s)
  西本新、Lu lingyun、林美里、西屋禎、堀之内孝広、三輪聡一
- Organizer
  第19回日本循環薬理学会
- Place of Presentation
  京都大学百周年時計台記念館(京都市)
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-21790237
[Presentation] Jab1, an ETAR-interacting protein, regulates ETAR level by promoting its degradation2009
- Author(s)
  西本新、Lu lingyun、林美里、西屋禎、堀之内孝広、三輪聡一
- Organizer
  第26回国際心臓研究学会日本部会
- Place of Presentation
  北海道大学学術交流会館(札幌市)
- Data Source
  KAKENHI-PROJECT-21790237
[Presentation] 受容体結合蛋白質Jab1によるエンドセリン受容体の発現レベル調節機構2009
- Author(s)
  西本新
- Organizer
  第19回日本循環薬理学会
- Place of Presentation
  京都大学百周年時計台記念館(京都府)
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-21390068
[Presentation] エンドセリンA型受容体結合蛋白質によるエンドセリンA型受容体蛋白質の分解制御機構の解明2008
- Author(s)
  西本新
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] 新規エンドセリンA型受容体(ET_AR)結合蛋白質Jab1によるET_ARレベルの調節2008
- Author(s)
  西本新
- Organizer
  第18回日本循環薬理学会
- Place of Presentation
  京成ホテルミラマーレ
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] エンドセリンA型受容体(ET_AR)結合蛋白質Jab1によるET_AR蛋白質分解制御機構の解明2008
- Author(s)
  西本新
- Organizer
  第59回日本薬理学会北部会
- Place of Presentation
  仙台市
- Year and Date
  2008-09-27
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] エンドセリンA型受容体結合蛋白質によるエンドセリンA型受容体蛋白質の分解制御機構の解明2008
- Author(s)
  西本新
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] 新規エンドセリンA型受容体(ETA_R)結合蛋白質Jab1によるET_ARレベルの調節2008
- Author(s)
  西本新
- Organizer
  第18回日本循環薬理学会
- Place of Presentation
  千葉
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] 新規エンドセリンA型受容体結合蛋白質jab1は、その受容体発現レベルとシグナル伝達を制御する2007
- Author(s)
  西本新
- Organizer
  第80回日本薬理学会年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] 新規エンドセリンA型受容体結合蛋白質Jab1は,その受容体発現レベルとシグナル伝達を制御する2007
- Author(s)
  西本新
- Organizer
  第11回日本適応医学会学術集会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2007-06-09
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] エンドセリンA型受容体(ET_AR)の蛋白質分解における新規結合蛋白質Jab1の役割2007
- Author(s)
  西本新
- Organizer
  第17回日本循環薬理学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] エンドセリンA型受容体(ETAR)の蛋白質分解における新規結合蛋白質Jab1の役割2007
- Author(s)
  西本新
- Organizer
  第58回日本薬理学会北部会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] エンドセリンA型受容体(ETAR)の蛋白質分解における新規結合蛋白質Jab1の役割2007
- Author(s)
  西本新
- Organizer
  第17回日本循環薬理学会
- Place of Presentation
  大阪大学(吹田市)
- Year and Date
  2007-11-30
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] 新規エンドセリンA型受容体結合蛋白質Jab1は,その受容体発現レベルとシグナル伝達を制御する、2007
- Author(s)
  西本新
- Organizer
  第11回日本適応医学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] エンドセリンA型受容体(ET_AR)の蛋白質分解における新規結合蛋白質Jab1の役割2007
- Author(s)
  西本新
- Organizer
  第58回日本薬理学会北部会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] 新規エンドセリン受容体会合蛋白質であるJab1のエンドセリン誘導性ERKリン酸化への関与2006
- Author(s)
  西本新
- Organizer
  第34回薬物活性シンポジウム
- Place of Presentation
  高崎
- Data Source
  KAKENHI-PROJECT-18390072
[Presentation] グルコース飢餓環境下でのヒト大腸癌細胞においてHIF-1αの活性化は、細胞生存力の亢進をもたらす
- Author(s)
  西本　新
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26462017

1. MIWA Soichi (40157706)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. NISHIYA Tadashi (80399831)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. HORINOUCHI Takahiro (20307771)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. UEDA Kazuhiro (90420520)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. TERADA Koji (70342722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HAYASHI Masataro (00554057)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 浜田淳一 (50192703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 多田光宏 (10241316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 榎忠彦 (80311819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 岡一斉 (40711271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 原田栄二郎 (90467803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 李桃生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishimoto Arata 西本 新

NISHIMOTO Arata 西本 新

西本 新 ニシモト アラタ

Research Projects

Research Products

Co-Researchers

Mechanisms of enhanced tumor growth during compensatory lung growth after major lung resection

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c-MYC, HIF-1による大腸癌の抗癌剤抵抗性獲得機構の解明

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Mechanism identification and Developing a novel method for therapy against lung cancer invasion via cancer-associated fibroblasts in pulmonary emphysema

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Elucidation of the role of Jab1 in malignant progression of colon cancerPrincipal Investigator

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Study of the regulatory mechanism of ETAR and ETBR level by receptor binding protein and the relevance between clinical significance and endothelin receptor level.

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Elucidation for pathophysiological significance of Jab1 as an inducer of endothelin type A receptor degradation in cardiovascular diseasesPrincipal Investigator

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Search for novel signal molecules which are directly activated by endothelin receptor

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miRNAによって引き起されるHOX遺伝子ネットワークの癌特異的破綻

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[Journal Article] Enhanced tumor growth in the remaining lung after major lung resection2016

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[Journal Article] Pulmonary emphysema and tumor microenvironment in primary lung cancer2016

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[Journal Article] The c-MYC-ABCB5 axis plays a pivotal role in 5-fluorouracil resistance in human colon cancer cells.2015

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[Journal Article] Hypoxic preconditioning reinforces cellular functions of autologous peripheral blood-derived cells in rabbit hindlimb ischemia model2014

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[Journal Article] HIF-1α activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells2014

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[Journal Article] HIF-1α activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells.2014

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Nishimoto Arata 西本新

NISHIMOTO Arata 西本新

西本新ニシモトアラタ