ADACHI MASATAKA 安達政隆

… Alternative Names

Adachi Masataka 安達政隆

ADACHI Masataka 安達政隆

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Researcher Number	90398206
Other IDs
Affiliation (Current)	2025: 熊本大学, 病院, 准教授
Affiliation (based on the past Project Information) *help	2025: 熊本大学, 病院, 准教授 2021 – 2023: 熊本大学, 病院, 准教授 2019 – 2020: 熊本大学, 病院, 講師 2012 – 2017: 熊本大学, 医学部附属病院, 助教 2007 – 2010: Kumamoto University, 医学部附属病院, 助教 2006: 熊本大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related
Keywords	Principal Investigator セリンプロテアーゼ / セリンプロテアーゼ阻害薬 / 臨床 / 薬学 / 生体分子 / 循環器・高血圧 / バゾプレッシン / 水チャネル / 水利尿 / 尿中バイオマーカー … More / 尿中トロンビン / 水・電解質代謝学 / 水・電解質学 / 水・電解質 / 高血圧学 / 上皮型ナトリウムチャネル / 高血圧 Less

RNA修飾を介したループス腎炎発症ならびに重症化に関する分子機序の解明Principal Investigator
- Principal Investigator
  
  安達政隆
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kumamoto University
セリンプロテアーゼによる尿濃縮メカニズムの解明Principal Investigator
- Principal Investigator
  
  安達政隆
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kumamoto University
Verification of the utility of urinary thrombin levels as a novel urinary biomarker for differential diagnosis of renal diseasesPrincipal Investigator
- Principal Investigator
  
  Adachi Masataka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kumamoto University
Elucidation of the physiological role of serine protease hepsin in the kidney.Principal Investigator
- Principal Investigator
  
  ADACHI MASATAKA
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kumamoto University
Elucidation of the molecular mechanism for the development of salt sensitive hypertension by serine proteases.Principal Investigator
- Principal Investigator
  
  ADACHI Masataka
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kumamoto University
Involvement of serine proteases in aldosterone-induced renal injury.Principal Investigator
- Principal Investigator
  
  ADACHI Masataka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kumamoto University
プロテアーゼネクシン1によるプロスタシンの阻害、降圧利尿薬開発への応用Principal Investigator
- Principal Investigator
  
  安達政隆
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kumamoto University

All 2023 2022 2017 2015 2012 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] The serine protease inhibitor camostat mesilate attenuates the progression of chronic kidney disease through its antioxidant effects.2015
- Author(s)
  Ueda, M., Uchimura, K., Narita, Y., Miyasato, Y., Mizumoto, T., Morinaga, J., Hayata, M., Kakizoe, Y., Adachi, M., Miyoshi, T., Shiraishi, N., Kadowaki, D., Sakai, Y., Mukoyama, M., and Kitamura, K.
- Journal Title
  
  Nephron
  
  Volume: 129 Pages: 223-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591231
[Journal Article] In vivo contribution of serine proteases to the proteolytic activation of γENaC in aldosterone-infused rats2012
- Author(s)
  Uchimura, K., Kakizoe, Y., Onoue, T., Hayata, M., Morinaga, J., Yamazoe, R., Ueda, M., Mizumoto, T., Adachi, M., Miyoshi, T., Shiraishi, N., Sakai, Y., Tomita, K., and Kitamura, K.
- Journal Title
  
  Am. J. Physiol. (Renal Physiol.)
  
  Volume: 303 Issue: 7 Pages: F939-F943
- DOI
  10.1152/ajprenal.00705.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591206, KAKENHI-PROJECT-24591207, KAKENHI-PROJECT-24591231
[Journal Article] Regulation of adrenal aldosterone production by serine protease prostasin2010
- Author(s)
  Ko T, Adachi M, et al.
- Journal Title
  
  Journal of Biomedicine and Biotechnology 2010
  
  Pages: 30-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590977
[Journal Article] Regulation of adrenal aldosterone production by serine protease prostasin.2010
- Author(s)
  Ko, T., Kakizoe, Y., Wakida, N., Hayata, M., Uchimura, K., Shiraishi, N., Miyoshi, T., Adachi, M., Aritomi, S., Konda, T., Tomita, K., Kitamura, K.
- Journal Title
  
  J Biomed Biotechnol. 2010
  
  Pages: 793843-793843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590977
[Journal Article] Aberrant ENaC activation in Dahl salt-sensitive rats.2009
- Author(s)
  Kakizoe, Y., Kitamura, K., Ko, T., Wakida, N., Maekawa, A., Miyoshi, T., Shiraishi, N., Adachi, M., Zhang, Z., Masilamani, S., Tomita, K.
- Journal Title
  
  J Hypertens. 27
  
  Pages: 1679-1689
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590977
[Journal Article] Aberrant ENaC activation in Dahl salt-sensitive rats2009
- Author(s)
  Kakizoe Y, Adachi M, et al.
- Journal Title
  
  Journal of Hypertension 27
  
  Pages: 1679-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590977
[Journal Article] Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension.2008
- Author(s)
  Maekawa, A., Kakizoe, Y., Miyoshi, T., Wakida, N., Ko, T., Shiraishi, N., Adachi, M., Tomita, K., Kitamura, K.
- Journal Title
  
  J hypertens. 26
  
  Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590977
[Journal Article] Camostat mesilate inhibits prostasin activity and reduces blood pres sure and renal injury in salt-sensitive hypertension.2008
- Author(s)
  Maekawa A, Adachi M, et al.
- Journal Title
  
  Journal of Hypertension 27
  
  Pages: 181-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590977
[Presentation] セリンプロテアーゼ阻害薬による水利尿効果の検討2023
- Author(s)
  柿添豊、中川輝政、岩田康伸、鄧欽元、宮里賢和、泉裕一郎、桒原孝成、安達政隆、向山政志
- Organizer
  第66回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08358
[Presentation] セリンプロテアーゼ阻害薬による尿エクソソーム中AQP2減少を伴う水利尿効果2022
- Author(s)
  柿添豊　中川輝政　岩田康伸　トウキンゲン　宮里賢和　泉裕一郎　桒原孝成　安達政隆　向山政志
- Organizer
  第26回日本心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08358
[Presentation] Serine protease inhibition exerts aquaretic effects and decreases urinary exosomal AQP2 levels2022
- Author(s)
  Yutaka Kakizoe, Yasunobu Iwata, Terumasa Nakagawa, Qinyuan Deng, Masataka Adachi, Yoshikazu Miyasato, Miyuki Nakagawa, Yu Nagayoshi, Kayo Nishiguchi, Yuki Narita, Yuichiro Izumi, Takashige Kuwabara, and Masashi Mukoyama
- Organizer
  第29回国際高血圧学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08358
[Presentation] 食塩感受性高血圧における糸球体障害を誘導するセリンプロテアーゼについての検討2017
- Author(s)
  岩田康伸, 中川輝政, 柿添豊, 泉裕一郎, 桑原孝成, 安達政隆, 北村健一郎, 向山政志
- Organizer
  日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-15K09291
[Presentation] 腎尿細管機能制御プロスタシンによるアルドステロン制御2012
- Author(s)
  安達政隆、こう健博、冨田公夫、北村健一郎
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜　会議場
- Data Source
  KAKENHI-PROJECT-24591231
[Presentation] アルドステロンによる腎障害に対するメシル酸カモスタットの効果2010
- Author(s)
  柿添豊、北村健一郎、内村幸平、森永潤、安達政隆, 他
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-20590977
[Presentation] プロスタシンによるアルドステロン産生誘導2008
- Author(s)
  健博、北村健一郎、脇田直樹、柿添豊、安達政隆, 他
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-06-01
- Data Source
  KAKENHI-PROJECT-20590977
[Presentation] プロスタシンによるアルドステロン産生誘導2008
- Author(s)
  〓健博, 安達政隆, 他
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590977
[Presentation] プロスタシンのNOによるENaC阻害における役割2007
- Author(s)
  安達政隆, 他
- Organizer
  第50回日本腎臓学会学術総会
- Place of Presentation
  アクトシティ浜松
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-18790569

1. 向山政志 (40270558)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
2. 北村健一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ADACHI MASATAKA 安達 政隆

Adachi Masataka 安達 政隆

ADACHI Masataka 安達 政隆

Research Projects

Research Products

Co-Researchers

RNA修飾を介したループス腎炎発症ならびに重症化に関する分子機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

セリンプロテアーゼによる尿濃縮メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Verification of the utility of urinary thrombin levels as a novel urinary biomarker for differential diagnosis of renal diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the physiological role of serine protease hepsin in the kidney.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the molecular mechanism for the development of salt sensitive hypertension by serine proteases.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of serine proteases in aldosterone-induced renal injury.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

プロテアーゼネクシン1によるプロスタシンの阻害、降圧利尿薬開発への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The serine protease inhibitor camostat mesilate attenuates the progression of chronic kidney disease through its antioxidant effects.2015

Author(s)

Journal Title

Data Source

[Journal Article] In vivo contribution of serine proteases to the proteolytic activation of γENaC in aldosterone-infused rats2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of adrenal aldosterone production by serine protease prostasin2010

Author(s)

Journal Title

Data Source

[Journal Article] Regulation of adrenal aldosterone production by serine protease prostasin.2010

Author(s)

Journal Title

Data Source

[Journal Article] Aberrant ENaC activation in Dahl salt-sensitive rats.2009

Author(s)

Journal Title

Data Source

[Journal Article] Aberrant ENaC activation in Dahl salt-sensitive rats2009

Author(s)

Journal Title

Data Source

[Journal Article] Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension.2008

Author(s)

Journal Title

Data Source

[Journal Article] Camostat mesilate inhibits prostasin activity and reduces blood pres sure and renal injury in salt-sensitive hypertension.2008

Author(s)

Journal Title

ADACHI MASATAKA 安達政隆

Adachi Masataka 安達政隆

ADACHI Masataka 安達政隆

[Presentation] 腎尿細管機能制御プロスタシンによるアルドステロン制御2012